{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T13:57:50Z","timestamp":1778335070749,"version":"3.51.4"},"reference-count":72,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T00:00:00Z","timestamp":1772668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T00:00:00Z","timestamp":1772668800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"crossref","award":["R01MH107549"],"award-info":[{"award-number":["R01MH107549"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R01HD116691"],"award-info":[{"award-number":["R01HD116691"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Brain Struct Funct"],"DOI":"10.1007\/s00429-026-03091-y","type":"journal-article","created":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T11:00:54Z","timestamp":1772708454000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Diffusion tensor imaging of cerebellar peduncles and association tracts in a case of primary complete callosal agenesis"],"prefix":"10.1007","volume":"231","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-9323-2401","authenticated-orcid":false,"given":"Jordi D.","family":"Martinez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5998-8445","authenticated-orcid":false,"given":"Eric","family":"Mooshagian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8042-8343","authenticated-orcid":false,"given":"Haley","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3332-4231","authenticated-orcid":false,"given":"Katherine H.","family":"Karlsgodt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2278-8962","authenticated-orcid":false,"given":"Lucina Q.","family":"Uddin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7129-3793","authenticated-orcid":false,"given":"Jason S.","family":"Nomi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,5]]},"reference":[{"issue":"1\u20132","key":"3091_CR1","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/0006-8993(92)90178-c","volume":"598","author":"F Aboitiz","year":"1992","unstructured":"Aboitiz F, Scheibel AB, Fisher RS, Zaidel E (1992) Fiber composition of the human corpus callosum. Brain Res 598(1\u20132):143\u2013153. https:\/\/doi.org\/10.1016\/0006-8993(92)90178-c","journal-title":"Brain Res"},{"issue":"2","key":"3091_CR2","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1007\/s12311-016-0815-8","volume":"16","author":"M Adamaszek","year":"2017","unstructured":"Adamaszek M, D\u2019Agata F, Ferrucci R, Habas C, Keulen S, Kirkby KC, Leggio M, Mari\u00ebn P, Molinari M, Moulton E, Orsi L, Van Overwalle F, Papadelis C, Priori A, Sacchetti B, Schutter DJ, Styliadis C, Verhoeven J (2017) Consensus paper: cerebellum and emotion. Cerebellum (Lond England) 16(2):552\u2013576. https:\/\/doi.org\/10.1007\/s12311-016-0815-8","journal-title":"Cerebellum (Lond England)"},{"issue":"22","key":"3091_CR3","doi-asserted-by":"publisher","first-page":"7418","DOI":"10.1523\/JNEUROSCI.4687-11.2012","volume":"32","author":"JR Alger","year":"2012","unstructured":"Alger JR (2012) The diffusion tensor imaging toolbox. J Neurosci 32(22):7418\u20137428. https:\/\/doi.org\/10.1523\/JNEUROSCI.4687-11.2012","journal-title":"J Neurosci"},{"issue":"2","key":"3091_CR4","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1016\/S1053-8119(03)00336-7","volume":"20","author":"JLR Andersson","year":"2003","unstructured":"Andersson JLR, Skare S, Ashburner J (2003) How to correct susceptibility distortions in spin-echo echo-planar images: application to diffusion tensor imaging. NeuroImage 20(2):870\u2013888. https:\/\/doi.org\/10.1016\/S1053-8119(03)00336-7","journal-title":"NeuroImage"},{"issue":"3","key":"3091_CR5","doi-asserted-by":"publisher","first-page":"242","DOI":"10.2399\/ana.16.044","volume":"10","author":"AG Aydin","year":"2016","unstructured":"Aydin AG, Adig\u00fczel E, Aksoy A, Acar K (2016) Partial corpus callosum agenesis and colpocephaly: a case report*. Anatomy 10(3):242\u2013245","journal-title":"Anatomy"},{"issue":"4","key":"3091_CR6","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1007\/s10578-007-0065-6","volume":"38","author":"DH Badaruddin","year":"2007","unstructured":"Badaruddin DH, Andrews GL, B\u00f6lte S, Schilmoeller KJ, Schilmoeller G, Paul LK, Brown WS (2007) Social and behavioral problems of children with agenesis of the corpus callosum. Child Psychiatry Hum Dev 38(4):287\u2013302. https:\/\/doi.org\/10.1007\/s10578-007-0065-6","journal-title":"Child Psychiatry Hum Dev"},{"issue":"1","key":"3091_CR7","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.nrl.2013.11.001","volume":"31","author":"EL Bartolom\u00e9","year":"2016","unstructured":"Bartolom\u00e9 EL, Cottura JC, Frescia B, R., Dom\u00ednguez RO (2016) Colpocefalia y agenesia parcial de cuerpo calloso asintom\u00e1ticos. Neurolog\u00eda 31(1):68\u201370. https:\/\/doi.org\/10.1016\/j.nrl.2013.11.001","journal-title":"Neurolog\u00eda"},{"issue":"1","key":"3091_CR8","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.neurobiolaging.2010.02.004","volume":"33","author":"B Bosch","year":"2012","unstructured":"Bosch B, Arenaza-Urquijo EM, Rami L, Sala-Llonch R, Junqu\u00e9 C, Sol\u00e9-Padull\u00e9s C, Pe\u00f1a-G\u00f3mez C, Bargall\u00f3 N, Molinuevo JL, Bartr\u00e9s-Faz D (2012) Multiple DTI index analysis in normal aging, amnestic MCI and AD. Relationship with neuropsychological performance. Neurobiol Aging 33(1):61\u201374. https:\/\/doi.org\/10.1016\/j.neurobiolaging.2010.02.004","journal-title":"Neurobiol Aging"},{"issue":"11","key":"3091_CR9","doi-asserted-by":"publisher","first-page":"14862","DOI":"10.18632\/aging.203183","volume":"13","author":"M Bouhrara","year":"2021","unstructured":"Bouhrara M, Cortina LE, Khattar N, Rejimon AC, Ajamu S, Cezayirli DS, Spencer RG (2021) Maturation and degeneration of the human brainstem across the adult lifespan. Aging 13(11):14862\u201314891. https:\/\/doi.org\/10.18632\/aging.203183","journal-title":"Aging"},{"issue":"2","key":"3091_CR70","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1080\/135468000395781","volume":"5","author":"WS Brown","year":"2000","unstructured":"Brown WS, Paul LK (2000) Cognitive and psychosocial deficits in agenesis of the corpus callosum with normal intelligence. Cogn Neuropsychiatry 5(2):135\u2013157. https:\/\/doi.org\/10.1080\/135468000395781","journal-title":"Cogn Neuropsychiatry"},{"issue":"3","key":"3091_CR10","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1017\/S135561771800111X","volume":"25","author":"WS Brown","year":"2019","unstructured":"Brown WS, Paul LK (2019) The neuropsychological syndrome of agenesis of the corpus callosum. J Int Neuropsychological Society: JINS 25(3):324\u2013330. https:\/\/doi.org\/10.1017\/S135561771800111X","journal-title":"J Int Neuropsychological Society: JINS"},{"issue":"1","key":"3091_CR11","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1046\/j.1440-1754.2001.00634.x","volume":"37","author":"JB Carlin","year":"2001","unstructured":"Carlin JB, Doyle LW (2001) Statistics for clinicians: 4: basic concepts of statistical reasoning: hypothesis tests and the t-test. J Paediatr Child Health 37(1):72\u201377. https:\/\/doi.org\/10.1046\/j.1440-1754.2001.00634.x","journal-title":"J Paediatr Child Health"},{"key":"3091_CR12","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.neuroimage.2016.11.068","volume":"147","author":"EH Chang","year":"2017","unstructured":"Chang EH, Argyelan M, Aggarwal M, Chandon T-SS, Karlsgodt KH, Mori S, Malhotra AK (2017) The role of myelination in measures of white matter integrity: Combination of diffusion tensor imaging and two-photon microscopy of CLARITY intact brains. NeuroImage 147:253\u2013261. https:\/\/doi.org\/10.1016\/j.neuroimage.2016.11.068","journal-title":"NeuroImage"},{"key":"3091_CR13","doi-asserted-by":"publisher","first-page":"120312","DOI":"10.1016\/j.neuroimage.2023.120312","volume":"280","author":"G Chau Loo Kung","year":"2023","unstructured":"Chau Loo Kung G, Knowles JK, Batra A, Ni L, Rosenberg J, McNab JA (2023) Quantitative MRI reveals widespread, network-specific myelination change during generalized epilepsy progression. NeuroImage 280:120312. https:\/\/doi.org\/10.1016\/j.neuroimage.2023.120312","journal-title":"NeuroImage"},{"issue":"1","key":"3091_CR14","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/j.jneumeth.2011.09.021","volume":"203","author":"H Cheng","year":"2011","unstructured":"Cheng H, Wang Y, Sheng J, Sporns O, Kronenberger WG, Mathews VP, Hummer TA, Saykin AJ (2011) Optimization of seed density in DTI tractography for structural networks. J Neurosci Methods 203(1):264\u2013272. https:\/\/doi.org\/10.1016\/j.jneumeth.2011.09.021","journal-title":"J Neurosci Methods"},{"issue":"5","key":"3091_CR15","first-page":"803","volume":"23","author":"NB Chepuri","year":"2002","unstructured":"Chepuri NB, Yen Y-F, Burdette JH, Li H, Moody DM, Maldjian JA (2002) Diffusion anisotropy in the corpus callosum. AJNR: Am J Neuroradiol 23(5):803\u2013808","journal-title":"AJNR: Am J Neuroradiol"},{"issue":"1","key":"3091_CR16","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/0093-934X(80)90116-9","volume":"11","author":"C Chiarello","year":"1980","unstructured":"Chiarello C (1980) A house divided? Cognitive functioning with callosal agenesis. Brain Lang 11(1):128\u2013158. https:\/\/doi.org\/10.1016\/0093-934X(80)90116-9","journal-title":"Brain Lang"},{"issue":"7","key":"3091_CR17","doi-asserted-by":"publisher","first-page":"980","DOI":"10.1016\/j.jpsychires.2011.01.006","volume":"45","author":"KA Clark","year":"2011","unstructured":"Clark KA, Nuechterlein KH, Asarnow RF, Hamilton LS, Phillips OR, Hageman NS, Woods RP, Alger JR, Toga AW, Narr KL (2011) Mean diffusivity and fractional anisotropy as indicators of disease and genetic liability to schizophrenia. J Psychiatr Res 45(7):980\u2013988. https:\/\/doi.org\/10.1016\/j.jpsychires.2011.01.006","journal-title":"J Psychiatr Res"},{"issue":"3","key":"3091_CR18","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1152\/jappl.1998.85.3.775","volume":"85","author":"D Curran-Everett","year":"1998","unstructured":"Curran-Everett D, Taylor S, Kafadar K (1998) Fundamental concepts in statistics: elucidation and illustration. J Appl Physiol (Bethesda Md : 1985) 85(3):775\u2013786. https:\/\/doi.org\/10.1152\/jappl.1998.85.3.775","journal-title":"J Appl Physiol (Bethesda Md : 1985)"},{"issue":"3","key":"3091_CR19","doi-asserted-by":"publisher","first-page":"e20160445","DOI":"10.1542\/peds.2016-0445","volume":"138","author":"F D\u2019Antonio","year":"2016","unstructured":"D\u2019Antonio F, Pagani G, Familiari A, Khalil A, Sagies T-L, Malinger G, Leibovitz Z, Garel C, Moutard ML, Pilu G, Bhide A, Acharya G, Leombroni M, Manzoli L, Papageorghiou A, Prefumo F (2016) Outcomes associated with isolated agenesis of the corpus callosum: a meta-analysis. Pediatrics 138(3):e20160445. https:\/\/doi.org\/10.1542\/peds.2016-0445","journal-title":"Pediatrics"},{"issue":"4","key":"3091_CR20","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1016\/0028-3932(76)90074-9","volume":"14","author":"M Dennis","year":"1976","unstructured":"Dennis M (1976) Impaired sensory and motor differentiation with corpus callosum agenesis: a lack of callosal inhibition during ontogeny? Neuropsychologia 14(4):455\u2013469. https:\/\/doi.org\/10.1016\/0028-3932(76)90074-9","journal-title":"Neuropsychologia"},{"key":"3091_CR21","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1038\/s41598-020-79540-3","volume":"11","author":"AV Dvorak","year":"2021","unstructured":"Dvorak AV, Swift-LaPointe T, Vavasour IM, Lee LE, Abel S, Russell-Schulz B, Graf C, Wurl A, Liu H, Laule C, Li DKB, Traboulsee A, Tam R, Boyd LA, MacKay AL, Kolind SH (2021) An atlas for human brain myelin content throughout the adult life span. Sci Rep 11:269. https:\/\/doi.org\/10.1038\/s41598-020-79540-3","journal-title":"Sci Rep"},{"key":"3091_CR22","doi-asserted-by":"publisher","unstructured":"Figley CR, Uddin MN, Wong K, Kornelsen J, Puig J, Figley TD (2022) Potential pitfalls of using fractional anisotropy, axial diffusivity, and radial diffusivity as biomarkers of cerebral white matter microstructure. Front Neurosci https:\/\/www.frontiersin.org\/articles\/https:\/\/doi.org\/10.3389\/fnins.2021.799576","DOI":"10.3389\/fnins.2021.799576"},{"issue":"19","key":"3091_CR23","doi-asserted-by":"publisher","first-page":"2495","DOI":"10.1002\/ajmg.a.32418","volume":"146A","author":"HC Glass","year":"2008","unstructured":"Glass HC, Shaw GM, Ma C, Sherr EH (2008) Agenesis of the corpus callosum in California 1983\u2009\u2013\u20092003: a population-based study. Am J Med Genet: A 146A(19):2495\u20132500. https:\/\/doi.org\/10.1002\/ajmg.a.32418","journal-title":"Am J Med Genet: A"},{"issue":"5","key":"3091_CR24","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.2214\/AJR.05.0146","volume":"187","author":"SW Hetts","year":"2006","unstructured":"Hetts SW, Sherr EH, Chao S, Gobuty S, Barkovich AJ (2006) Anomalies of the corpus callosum: an MR analysis of the phenotypic spectrum of associated malformations. AJR Am J Roentgenol 187(5):1343\u20131348. https:\/\/doi.org\/10.2214\/AJR.05.0146","journal-title":"AJR Am J Roentgenol"},{"key":"3091_CR25","doi-asserted-by":"publisher","unstructured":"Hofman J, Hutny M, Sztuba K, Paprocka J, Hofman J, Hutny M, Sztuba K, Paprocka J (2020) Corpus callosum agenesis: an insight into the etiology and spectrum of symptoms. Brain Sci https:\/\/doi.org\/10.3390\/brainsci10090625","DOI":"10.3390\/brainsci10090625"},{"issue":"2","key":"3091_CR26","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1002\/(SICI)1096-9861","volume":"387","author":"PR Huttenlocher","year":"1997","unstructured":"Huttenlocher PR, Dabholkar AS (1997) Regional differences in synaptogenesis in human cerebral cortex. J Comp Neurol 387(2):167\u2013178. https:\/\/doi.org\/10.1002\/(SICI)1096-9861::AID-CNE1>3.0.CO;2-Z","journal-title":"J Comp Neurol"},{"issue":"4496","key":"3091_CR27","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1126\/science.7221566","volume":"212","author":"GM Innocenti","year":"1981","unstructured":"Innocenti GM (1981) Growth and reshaping of axons in the establishment of visual callosal connections. Science 212(4496):824\u2013827. https:\/\/doi.org\/10.1126\/science.7221566","journal-title":"Science"},{"issue":"1","key":"3091_CR28","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.ejpn.2016.07.007","volume":"21","author":"FY Ismail","year":"2017","unstructured":"Ismail FY, Fatemi A, Johnston MV (2017) Cerebral plasticity: windows of opportunity in the developing brain. Eur J Pediatr Neurol 21(1):23\u201348. https:\/\/doi.org\/10.1016\/j.ejpn.2016.07.007","journal-title":"Eur J Pediatr Neurol"},{"issue":"11","key":"3091_CR29","doi-asserted-by":"publisher","first-page":"2747","DOI":"10.1002\/hbm.22099","volume":"34","author":"B Jeurissen","year":"2013","unstructured":"Jeurissen B, Leemans A, Tournier J-D, Jones DK, Sijbers J (2013) Investigating the prevalence of complex fiber configurations in white matter tissue with diffusion magnetic resonance imaging. Hum Brain Mapp 34(11):2747\u20132766. https:\/\/doi.org\/10.1002\/hbm.22099","journal-title":"Hum Brain Mapp"},{"issue":"June","key":"3091_CR30","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/j.neuroimage.2012.06.081","volume":"73","author":"DK Jones","year":"2013","unstructured":"Jones DK, Thomas R, Kn\u00f6sche, Turner R (2013) White matter integrity, fiber count, and other fallacies: The Do\u2019s and Don\u2019ts of diffusion MRI. NeuroImage 73(June):239\u2013254. https:\/\/doi.org\/10.1016\/j.neuroimage.2012.06.081","journal-title":"NeuroImage"},{"issue":"3","key":"3091_CR31","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.bpsc.2015.12.001","volume":"1","author":"KH Karlsgodt","year":"2016","unstructured":"Karlsgodt KH (2016) Diffusion imaging of white matter in schizophrenia: progress and future directions. Biol Psychiatry Cogn Neurosci Neuroimaging 1(3):209\u2013217. https:\/\/doi.org\/10.1016\/j.bpsc.2015.12.001","journal-title":"Biol Psychiatry: Cogn Neurosci Neuroimaging"},{"key":"3091_CR32","doi-asserted-by":"publisher","first-page":"41","DOI":"10.3389\/fnana.2015.00041","volume":"9","author":"Z Keser","year":"2015","unstructured":"Keser Z, Hasan KM, Mwangi BI, Kamali A, Ucisik-Keser FE, Riascos RF, Yozbatiran N, Francisco GE, Narayana PA (2015) Diffusion tensor imaging of the human cerebellar pathways and their interplay with cerebral macrostructure. Front Neuroanat 9:41. https:\/\/doi.org\/10.3389\/fnana.2015.00041","journal-title":"Front Neuroanat"},{"issue":"5","key":"3091_CR71","doi-asserted-by":"publisher","first-page":"391","DOI":"10.3348\/kjr.2008.9.5.391","volume":"9","author":"EY Kim","year":"2008","unstructured":"Kim EY, Park HJ, Kim DH, Lee SK, Kim J (2008) Measuring fractional anisotropy of the corpus callosum using diffusion tensor imaging: mid-sagittal versus axial imaging planes. Korean J Radiol 9(5):391\u2013395. https:\/\/doi.org\/10.3348\/kjr.2008.9.5.391","journal-title":"Korean J Radiol"},{"issue":"11","key":"3091_CR33","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1097\/RLI.0000000000000394","volume":"52","author":"M Kronlage","year":"2017","unstructured":"Kronlage M, Pitarokoili K, Schwarz D, Godel T, Heiland S, Yoon M-S, Bendszus M, B\u00e4umer P (2017) Diffusion tensor imaging in chronic inflammatory demyelinating polyneuropathy: diagnostic accuracy and correlation with electrophysiology. Invest Radiol 52(11):701\u2013707. https:\/\/doi.org\/10.1097\/RLI.0000000000000394","journal-title":"Invest Radiol"},{"issue":"5","key":"3091_CR34","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/S0387-7604(89)80059-2","volume":"11","author":"J Landman","year":"1989","unstructured":"Landman J, Weitz R, Dulitzki F, Shuper A, Sirota L, Aloni D, Bar-Ziv J, Gadoth N (1989) Radiological colpocephaly: a congenital malformation or the result of intrauterine and perinatal brain damage. Brain Develop 11(5):313\u2013316. https:\/\/doi.org\/10.1016\/S0387-7604(89)80059-2","journal-title":"Brain Develop"},{"issue":"6","key":"3091_CR35","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1007\/s12311-015-0652-1","volume":"14","author":"Y Leitner","year":"2015","unstructured":"Leitner Y, Travis KE, Ben-Shachar M, Yeom KW, Feldman HM (2015) Tract profiles of the cerebellar white matter pathways in children and adolescents. Cerebellum 14(6):613\u2013623. https:\/\/doi.org\/10.1007\/s12311-015-0652-1","journal-title":"Cerebellum"},{"issue":"5","key":"3091_CR36","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.1007\/s00330-014-3541-y","volume":"25","author":"A Meoded","year":"2015","unstructured":"Meoded A, Katipally R, Bosemani T, Huisman TAGM, Poretti A (2015) Structural connectivity analysis reveals abnormal brain connections in agenesis of the corpus callosum in children. Eur Radiol 25(5):1471\u20131478. https:\/\/doi.org\/10.1007\/s00330-014-3541-y","journal-title":"Eur Radiol"},{"issue":"5","key":"3091_CR37","doi-asserted-by":"publisher","first-page":"1406","DOI":"10.3171\/2015.4.JNS142741","volume":"124","author":"A Meola","year":"2016","unstructured":"Meola A, Comert A, Yeh F-C, Sivakanthan S, Fernandez-Miranda JC (2016) The nondecussating pathway of the dentatorubrothalamic tract in humans: Human connectome-based tractographic study and microdissection validation. J Neurosurg 124(5):1406\u20131412. https:\/\/doi.org\/10.3171\/2015.4.JNS142741","journal-title":"J Neurosurg"},{"key":"3091_CR38","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.neuroimage.2016.07.044","volume":"141","author":"KL Mills","year":"2016","unstructured":"Mills KL, Goddings A-L, Herting MM, Meuwese R, Blakemore S-J, Crone EA, Dahl RE, G\u00fcro\u011flu B, Raznahan A, Sowell ER, Tamnes CK (2016) Structural brain development between childhood and adulthood: convergence across four longitudinal samples. NeuroImage 141:273\u2013281. https:\/\/doi.org\/10.1016\/j.neuroimage.2016.07.044","journal-title":"NeuroImage"},{"key":"3091_CR39","doi-asserted-by":"publisher","first-page":"110484","DOI":"10.1016\/j.ijscr.2024.110484","volume":"124","author":"S Mirzaei","year":"2024","unstructured":"Mirzaei S, Motaghed Z, Zarei H (2024) Colpocephaly and corpus callosum dysgenesis in an adult: a rare case report. Int J Surg Case Rep 124:110484. https:\/\/doi.org\/10.1016\/j.ijscr.2024.110484","journal-title":"Int J Surg Case Rep"},{"issue":"12","key":"3091_CR40","doi-asserted-by":"publisher","first-page":"438","DOI":"10.4329\/wjr.v7.i12.438","volume":"7","author":"H Morales","year":"2015","unstructured":"Morales H, Tomsick T (2015) Middle cerebellar peduncles: magnetic resonance imaging and pathophysiologic correlate. World J Radiol 7(12):438\u2013447. https:\/\/doi.org\/10.4329\/wjr.v7.i12.438","journal-title":"World J Radiol"},{"issue":"4","key":"3091_CR41","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1016\/j.neuron.2017.07.009","volume":"95","author":"CW Mount","year":"2017","unstructured":"Mount CW, Monje M (2017) Wrapped to adapt: experience-dependent myelination. Neuron 95(4):743\u2013756. https:\/\/doi.org\/10.1016\/j.neuron.2017.07.009","journal-title":"Neuron"},{"issue":"5","key":"3091_CR42","doi-asserted-by":"publisher","first-page":"1897","DOI":"10.1007\/s00429-019-01864-2","volume":"224","author":"JS Nomi","year":"2019","unstructured":"Nomi JS, Marshall E, Zaidel E, Biswal B, Castellanos FX, Dick AS, Uddin LQ, Mooshagian E (2019) Diffusion weighted imaging evidence of extra-callosal pathways for interhemispheric communication after complete commissurotomy. Brain Struct Function 224(5):1897\u20131909. https:\/\/doi.org\/10.1007\/s00429-019-01864-2","journal-title":"Brain Struct Function"},{"key":"3091_CR43","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/j.neuroimage.2012.12.031","volume":"70","author":"JP Owen","year":"2013","unstructured":"Owen JP, Li Y-O, Ziv E, Strominger Z, Gold J, Bukhpun P, Wakahiro M, Friedman EJ, Sherr EH, Mukherjee P (2013) The structural connectome of the human brain in agenesis of the corpus callosum. NeuroImage 70:340\u2013355. https:\/\/doi.org\/10.1016\/j.neuroimage.2012.12.031","journal-title":"NeuroImage"},{"issue":"1","key":"3091_CR44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S1090-7807(02)00178-7","volume":"161","author":"S Pajevic","year":"2003","unstructured":"Pajevic S, Basser PJ (2003) Parametric and non-parametric statistical analysis of DT-MRI data. J Magn Reson 161(1):1\u201314. https:\/\/doi.org\/10.1016\/S1090-7807(02)00178-7","journal-title":"J Magn Reson"},{"key":"3091_CR45","doi-asserted-by":"publisher","unstructured":"Palesi F, De Rinaldis A, Castellazzi G, Calamante F, Muhlert N, Chard D, Tournier JD, Magenes G, D\u2019Angelo E, Wheeler-Kingshott G (2017) Contralateral cortico-ponto-cerebellar pathways reconstruction in humans in vivo: Implications for reciprocal cerebro-cerebellar structural connectivity in motor and non-motor areas. Sci Rep https:\/\/doi.org\/10.1038\/s41598-017-13079-8","DOI":"10.1038\/s41598-017-13079-8"},{"key":"3091_CR48","doi-asserted-by":"publisher","unstructured":"P\u00e2nzaru M-C, Popa S, Lupu A, Gavrilovici C, Lupu VV, Gorduza EV (2022) Genetic heterogeneity in corpus callosum agenesis. Front Genet https:\/\/doi.org\/10.3389\/fgene.2022.958570","DOI":"10.3389\/fgene.2022.958570"},{"issue":"3","key":"3091_CR46","doi-asserted-by":"publisher","first-page":"2190","DOI":"10.1016\/j.neuroimage.2009.10.071","volume":"49","author":"O Pasternak","year":"2010","unstructured":"Pasternak O, Sochen N, Basser PJ (2010) The effect of metric selection on the analysis of diffusion tensor MRI data. NeuroImage 49(3):2190\u20132204. https:\/\/doi.org\/10.1016\/j.neuroimage.2009.10.071","journal-title":"NeuroImage"},{"issue":"4","key":"3091_CR47","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1038\/nrn2107","volume":"8","author":"LK Paul","year":"2007","unstructured":"Paul LK, Brown WS, Adolphs R, Tyszka JM, Richards LJ, Mukherjee P, Sherr EH (2007) Agenesis of the corpus callosum: genetic, developmental and functional aspects of connectivity. Nat Rev Neurosci 8(4):287\u2013299. https:\/\/doi.org\/10.1038\/nrn2107","journal-title":"Nat Rev Neurosci"},{"key":"3091_CR72","unstructured":"Posit team (2025) RStudio: Integrated Development Environment for R. Posit Software, PBC, Boston, MA. URL http:\/\/www.posit.co\/"},{"issue":"1","key":"3091_CR49","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1002\/cne.901320103","volume":"132","author":"P Rakic","year":"1968","unstructured":"Rakic P, Yakovlev PI (1968) Development of the corpus callosum and cavum septi in man. J Comp Neurol 132(1):45\u201372. https:\/\/doi.org\/10.1002\/cne.901320103","journal-title":"J Comp Neurol"},{"issue":"1","key":"3091_CR50","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1177\/08830738251345652","volume":"41","author":"R Rashid","year":"2025","unstructured":"Rashid R, Bach A, Gebb J, Soni S, Patel V, Saha K, Miller K, Schindewolf E, Cristancho AG, Agarwal S (2025) Agenesis of corpus callosum: a clinical study of complete versus partial agenesis in a 20-Year retrospective cohort. J Child Neurol 41(1):34\u201342. https:\/\/doi.org\/10.1177\/08830738251345652","journal-title":"J Child Neurol"},{"issue":"6","key":"3091_CR51","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1007\/s00234-010-0696-3","volume":"52","author":"C Raybaud","year":"2010","unstructured":"Raybaud C (2010) The corpus callosum, the other great forebrain commissures, and the septum pellucidum: anatomy, development, and malformation. Neuroradiology 52(6):447\u2013477. https:\/\/doi.org\/10.1007\/s00234-010-0696-3","journal-title":"Neuroradiology"},{"issue":"3","key":"3091_CR52","doi-asserted-by":"publisher","first-page":"1243","DOI":"10.1007\/s00429-016-1274-1","volume":"222","author":"KL Ruddy","year":"2017","unstructured":"Ruddy KL, Leemans A, Carson RG (2017) Transcallosal connectivity of the human cortical motor network. Brain Struct Function 222(3):1243\u20131252. https:\/\/doi.org\/10.1007\/s00429-016-1274-1","journal-title":"Brain Struct Function"},{"key":"3091_CR53","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1007\/s00429-022-02600-z","volume":"228","author":"S Sandrone","year":"2023","unstructured":"Sandrone S, Aiello M, Cavaliere C et al (2023) Mapping myelin in white matter with T1-weighted\/T2-weighted maps: discrepancy with histology and other myelin MRI measures. Brain Struct Funct 228:525\u2013535. https:\/\/doi.org\/10.1007\/s00429-022-02600-z","journal-title":"Brain Struct Funct"},{"key":"3091_CR54","doi-asserted-by":"publisher","unstructured":"Schilling K, Gao Y, Janve V, Stepniewska I, Landman BA, Anderson AW (2017) Can increased spatial resolution solve the crossing fiber problem for diffusion MRI? NMR Biomed https:\/\/doi.org\/10.1002\/nbm.3787","DOI":"10.1002\/nbm.3787"},{"key":"3091_CR55","unstructured":"Shenoy SS, Lui F (2023) Neuroanatomy, ventricular system. In: StatPearls. StatPearls Publishing. http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK532932\/"},{"issue":"2","key":"3091_CR56","doi-asserted-by":"publisher","first-page":"1227","DOI":"10.1093\/cercor\/bhaa289","volume":"31","author":"V Siffredi","year":"2021","unstructured":"Siffredi V, Preti MG, Kebets V, Obertino S, Leventer RJ, McIlroy A, Wood AG, Anderson V, Spencer-Smith MM, Van De Ville D (2021a) Structural neuroplastic responses preserve functional connectivity and neurobehavioural outcomes in children born without corpus callosum. Cereb Cortex 31(2):1227\u20131239. https:\/\/doi.org\/10.1093\/cercor\/bhaa289","journal-title":"Cereb Cortex"},{"key":"3091_CR57","doi-asserted-by":"publisher","first-page":"118471","DOI":"10.1016\/j.neuroimage.2021.118471","volume":"243","author":"V Siffredi","year":"2021","unstructured":"Siffredi V, Farouj Y, Tarun A, Anderson V, Wood AG, McIlroy A, Leventer RJ, Spencer-Smith MM, Ville DVD (2021b) Large-scale functional network dynamics in human callosal agenesis: increased subcortical involvement and preserved laterality. NeuroImage 243:118471. https:\/\/doi.org\/10.1016\/j.neuroimage.2021.118471","journal-title":"NeuroImage"},{"key":"3091_CR58","doi-asserted-by":"publisher","first-page":"31","DOI":"10.3389\/fnins.2013.00031","volume":"7","author":"JM Soares","year":"2013","unstructured":"Soares JM, Marques P, Alves V, Sousa N (2013) A hitchhiker\u2019s guide to diffusion tensor imaging. Front NeuroSci 7:31. https:\/\/doi.org\/10.3389\/fnins.2013.00031","journal-title":"Front NeuroSci"},{"issue":"5","key":"3091_CR59","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.tics.2017.02.005","volume":"21","author":"AA Sokolov","year":"2017","unstructured":"Sokolov AA, Miall RC, Ivry RB (2017) The cerebellum: adaptive prediction for movement and cognition. Trends Cogn Sci 21(5):313\u2013332. https:\/\/doi.org\/10.1016\/j.tics.2017.02.005","journal-title":"Trends Cogn Sci"},{"issue":"1","key":"3091_CR60","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.neuroimage.2005.01.028","volume":"26","author":"S-K Song","year":"2005","unstructured":"Song S-K, Yoshino J, Le TQ, Lin S-J, Sun S-W, Cross AH, Armstrong RC (2005) Demyelination increases radial diffusivity in corpus callosum of mouse brain. NeuroImage 26(1):132\u2013140. https:\/\/doi.org\/10.1016\/j.neuroimage.2005.01.028","journal-title":"NeuroImage"},{"key":"3091_CR61","doi-asserted-by":"publisher","first-page":"611451","DOI":"10.3389\/fnins.2021.611451","volume":"15","author":"N Soni","year":"2021","unstructured":"Soni N, Medeiros R, Alateeq K, To XV, Nasrallah FA (2021) Diffusion tensor imaging detects acute pathology-specific changes in the P301L tauopathy mouse model following traumatic brain injury. Front Neuro Sci 15:611451. https:\/\/doi.org\/10.3389\/fnins.2021.611451","journal-title":"Front Neuro Sci"},{"issue":"3","key":"3091_CR62","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1093\/cercor\/bhj178","volume":"17","author":"F Tovar-Moll","year":"2007","unstructured":"Tovar-Moll F, Moll J, de Oliveira-Souza R, Bramati I, Andreiuolo PA, Lent R (2007) Neuroplasticity in human callosal dysgenesis: a diffusion tensor imaging study. Cereb Cortex 17(3):531\u2013541. https:\/\/doi.org\/10.1093\/cercor\/bhj178","journal-title":"Cereb Cortex"},{"issue":"21","key":"3091_CR63","doi-asserted-by":"publisher","first-page":"7843","DOI":"10.1073\/pnas.1400806111","volume":"111","author":"F Tovar-Moll","year":"2014","unstructured":"Tovar-Moll F, Monteiro M, Andrade J, Bramati IE, Vianna-Barbosa R, Marins T, Rodrigues E, Dantas N, Behrens TEJ, de Oliveira-Souza R, Moll J, Lent R (2014) Structural and functional brain rewiring clarifies preserved interhemispheric transfer in humans born without the corpus callosum. Proc Natl Acad Sci USA 111(21):7843\u20137848. https:\/\/doi.org\/10.1073\/pnas.1400806111","journal-title":"Proc Natl Acad Sci USA"},{"issue":"6","key":"3091_CR64","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1002\/ana.24641","volume":"79","author":"T-W Tu","year":"2016","unstructured":"Tu T-W, Williams RA, Lescher JD, Jikaria N, Turtzo LC, Frank JA (2016) Radiological-pathological correlation of diffusion tensor and magnetization transfer imaging in a closed head traumatic brain injury model. Ann Neurol 79(6):907\u2013920. https:\/\/doi.org\/10.1002\/ana.24641","journal-title":"Ann Neurol"},{"issue":"6","key":"3091_CR65","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1080\/87565641.2017.1334783","volume":"42","author":"C Vias","year":"2017","unstructured":"Vias C, Dick AS (2017) Cerebellar contributions to language in typical and atypical development: a review. Dev Neuropsychol 42(6):404\u2013421. https:\/\/doi.org\/10.1080\/87565641.2017.1334783","journal-title":"Dev Neuropsychol"},{"key":"3091_CR66","doi-asserted-by":"publisher","first-page":"92","DOI":"10.3389\/fneur.2018.00092","volume":"9","author":"PJ Winklewski","year":"2018","unstructured":"Winklewski PJ, Sabisz A, Naumczyk P, Jodzio K, Szurowska E, Szarmach A (2018) Understanding the physiopathology behind axial and radial diffusivity changes\u2014what do we know? Front Neurol 9:92. https:\/\/doi.org\/10.3389\/fneur.2018.00092","journal-title":"Front Neurol"},{"issue":"11","key":"3091_CR67","doi-asserted-by":"publisher","first-page":"e80713","DOI":"10.1371\/journal.pone.0080713","volume":"8","author":"F-C Yeh","year":"2013","unstructured":"Yeh F-C, Verstynen TD, Wang Y, Fern\u00e1ndez-Miranda JC, Tseng W-YI (2013) Deterministic diffusion fiber tracking improved by quantitative anisotropy. PLoS ONE 8(11):e80713. https:\/\/doi.org\/10.1371\/journal.pone.0080713","journal-title":"PLoS ONE"},{"issue":"1","key":"3091_CR68","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1007\/s13311-018-0663-y","volume":"16","author":"F-C Yeh","year":"2019","unstructured":"Yeh F-C, Panesar S, Barrios J, Fernandes D, Abhinav K, Meola A, Fernandez-Miranda JC (2019) Automatic removal of false connections in diffusion mri tractography using Topology-Informed Pruning (TIP). Neurotherapeutics: J Am Soc Experimental Neurother 16(1):52\u201358. https:\/\/doi.org\/10.1007\/s13311-018-0663-y","journal-title":"Neurotherapeutics: J Am Soc Experimental Neurother"},{"key":"3091_CR69","doi-asserted-by":"publisher","first-page":"102425","DOI":"10.1016\/j.nicl.2020.102425","volume":"28","author":"J Yuan","year":"2020","unstructured":"Yuan J, Song X, Kuan E, Wang S, Zuo L, Ongur D, Hu W, Du F (2020) The structural basis for interhemispheric functional connectivity: evidence from individuals with agenesis of the corpus callosum. NeuroImage: Clin 28:102425. https:\/\/doi.org\/10.1016\/j.nicl.2020.102425","journal-title":"NeuroImage: Clin"}],"container-title":["Brain Structure and Function"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00429-026-03091-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00429-026-03091-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00429-026-03091-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T08:01:10Z","timestamp":1778054470000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00429-026-03091-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,5]]},"references-count":72,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,4]]}},"alternative-id":["3091"],"URL":"https:\/\/doi.org\/10.1007\/s00429-026-03091-y","relation":{},"ISSN":["1863-2661"],"issn-type":[{"value":"1863-2661","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,5]]},"assertion":[{"value":"31 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"36"}}