{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T09:38:52Z","timestamp":1791020332025,"version":"4.1.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1-2","license":[{"start":{"date-parts":[[2004,3,2]],"date-time":"2004-03-02T00:00:00Z","timestamp":1078185600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2004,3,2]],"date-time":"2004-03-02T00:00:00Z","timestamp":1078185600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Microbiol Immunol"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1007\/s00430-003-0202-1","type":"journal-article","created":{"date-parts":[[2004,7,22]],"date-time":"2004-07-22T13:55:08Z","timestamp":1090504508000},"page":"7-12","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":73,"title":["Quantitative real time PCR detection of Varicella-zoster virus DNA in cerebrospinal fluid in patients with neurological disease"],"prefix":"10.1007","volume":"194","author":[{"given":"Stephan W.","family":"Aberle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith H.","family":"Aberle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Steininger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Puchhammer-St\u00f6ckl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2004,3,2]]},"reference":[{"key":"202_CR1","doi-asserted-by":"crossref","unstructured":"Aberle SW, Puchhammer-St\u00f6ckl E (2002) Diagnosis of herpesvirus infections of the central nervous system. J Clin Virol 25 [Suppl 1]:S79-S85","DOI":"10.1016\/S1386-6532(02)00037-9"},{"key":"202_CR2","unstructured":"Arvin AM (2001) Varicella-Zoster Virus. In: Knipe DM, HowleyPM (eds), Fields virology. Lippincott Williams & Wilkins, Philadelphia, pp 2731\u20132767"},{"key":"202_CR3","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0733-8619(18)30998-8","volume":"4","author":"Barnes","year":"1986","unstructured":"Barnes DW, Whitley RJ (1986) CNS diseases associated with varicella zoster virus and herpes simplex virus infection. Pathogenesis and current therapy. Neurol Clin 4:265\u2013283","journal-title":"Neurol Clin"},{"key":"202_CR4","first-page":"41","volume":"100","author":"T Bergstrom","year":"1996","unstructured":"Bergstrom T (1996) Polymerase chain reaction for diagnosis of varicella zoster virus central nervous system infections without skin manifestations. Scand J Infect Dis [Suppl] 100:41\u201345","journal-title":"Scand J Infect Dis [Suppl]"},{"key":"202_CR5","first-page":"1019","volume":"97","author":"Bessho","year":"1994","unstructured":"Bessho K, Ogino S (1994). Detection of varicella-zoster virus DNA by polymerase chain reaction in patients with Hunt syndrome and clinical progression. Nippon Jibiinkoka Gakkai Kaiho 97:1019\u20131027","journal-title":"Nippon Jibiinkoka Gakkai Kaiho"},{"key":"202_CR6","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1086\/513754","volume":"25","author":"Cinque","year":"1997","unstructured":"Cinque P, Bossolasco S, Vago L, Fornaia C, Lipari S, Racca S, Lazzarin A, Linde A (1997) Varicella-zoster virus (VZV) DNA in cerebrospinal fluid of patients infected with human immunodeficiency virus: VZV disease of the central nervous system or subclinical reactivation of VZV infection? Clin Infect Dis 25:634\u2013639","journal-title":"Clin Infect Dis"},{"key":"202_CR7","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1128\/JCM.36.8.2229-2234.1998","volume":"36","author":"Domingues,","year":"1998","unstructured":"Domingues, RB, Lakeman FD, Mayo MS, Whitley RJ (1998) Application of competitive PCR to cerebrospinal fluid samples from patients with herpes simplex encephalitis. J Clin Microbiol 36:2229\u20132234","journal-title":"J Clin Microbiol"},{"key":"202_CR8","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1159\/000150535","volume":"40","author":"Echevarria","year":"1997","unstructured":"Echevarria JM, Casas I, Martinez-Martin P (1997) Infections of the nervous system caused by varicella-zoster virus: a review. Intervirology 40:72\u201384","journal-title":"Intervirology"},{"key":"202_CR9","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1002\/jmv.1890430403","volume":"43","author":"Echevarria","year":"1994","unstructured":"Echevarria JM, Casas I, Tenorio A, de Ory F, Martinez-Martin P (1994) Detection of varicella-zoster virus-specific DNA sequences in cerebrospinal fluid from patients with acute aseptic meningitis and no cutaneous lesions. J Med Virol 43:331\u2013335","journal-title":"J Med Virol"},{"key":"202_CR10","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1093\/infdis\/166.5.1157","volume":"166","author":"Furuta","year":"1992","unstructured":"Furuta Y, Takasu T, Fukuda S, Sato-Matsumura KC, Inuyama Y, Hondo R, Nagashima K (1992) Detection of varicella-zoster virus DNA in human geniculate ganglia by polymerase chain reaction. J Infect Dis 166:1157\u20131159","journal-title":"J Infect Dis"},{"key":"202_CR11","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1002\/ana.410350505","volume":"35","author":"Gilden","year":"1994","unstructured":"Gilden DH, Wright RR, Schneck SA, Gwaltney JM Jr, Mahalingam R (1994) Zoster sine herpete, a clinical variant. Ann Neurol 35:530\u2013533","journal-title":"Ann Neurol"},{"key":"202_CR12","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1056\/NEJM200003023420906","volume":"342","author":"Gilden","year":"2000","unstructured":"Gilden DH, Kleinschmidt-DeMasters BK, LaGuardia JJ, Mahalingam R, Cohrs RJ (2000) Neurologic complications of the reactivation of varicella-zoster virus. N Engl J Med 342:635\u2013645","journal-title":"N Engl J Med"},{"key":"202_CR13","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1212\/WNL.51.5.1405","volume":"51","author":"Haanpaa","year":"1998","unstructured":"Haanpaa M, Dastidar P, Weinberg A, Levin M, Miettinen A, Lapinlampi A, Laippala P, Nurmikko T (1998) CSF and MRI findings in patients with acute herpes zoster. Neurology 51:1405\u20131411","journal-title":"Neurology"},{"key":"202_CR14","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1097\/00005792-198303000-00002","volume":"62","author":"Jemsek","year":"1983","unstructured":"Jemsek J, Greenberg SB, Taber L, Harvey D, Gershon A, Couch RB (1983) Herpes zoster-associated encephalitis: clinicopathologic report of 12 cases and review of the literature. Medicine 62:81\u201397","journal-title":"Medicine"},{"key":"202_CR15","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1136\/jnnp.46.6.582-a","volume":"46","author":"Karp","year":"1983","unstructured":"Karp SJ (1983) Meningitis and disseminated cutaneous zoster complicating herpes zoster infection. J Neurol Neurosurg Psychiatry 46:582\u2013583","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"202_CR16","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1111\/j.1750-3639.2001.tb00413.x","volume":"11","author":"Kleinschmidt-DeMasters","year":"2001","unstructured":"Kleinschmidt-DeMasters BK, Gilden DH (2001) The expanding spectrum of herpesvirus infections of the nervous system. Brain Pathol 11:440\u2013451","journal-title":"Brain Pathol"},{"key":"202_CR17","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/S1386-6532(02)00020-3","volume":"25","author":"Koskiniemi","year":"2002","unstructured":"Koskiniemi M, Piiparinen H, Rantalaiho T, Eranko P, Farkkila M, Raiha K, Salonen EM, Ukkonen P, Vaheri A (2002) Acute central nervous system complications in varicella zoster virus infections. J Clin Virol 25:293\u2013301","journal-title":"J Clin Virol"},{"key":"202_CR18","first-page":"4","volume":"5","author":"Martinez-Martin","year":"1990","unstructured":"Martinez-Martin P, Herreros A, Tellez A, Echevarria JM (1990) Meningitis of viral or possible viral etiology in adults: study of 325 cases. Neurologia 5:4\u201310","journal-title":"Neurologia"},{"key":"202_CR19","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1001\/archneur.1969.00480180015001","volume":"21","author":"McCormick","year":"1969","unstructured":"McCormick WF, Rodnitzky RL, Schochet SS Jr, McKee AP (1969) Varicella-Zoster encephalomyelitis. A morphologic and virologic study. Arch Neurol 21:559\u2013570","journal-title":"Arch Neurol"},{"key":"202_CR20","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1080\/00313020120105705","volume":"34","author":"McKelvie","year":"2002","unstructured":"McKelvie PA, Collins S, Thyagarajan D, Trost N, Sheorey H, Byrne E (2002) Meningoencephalomyelitis with vasculitis due to varicella zoster virus: a case report and review of the literature. Pathology 34:88\u201393","journal-title":"Pathology"},{"key":"202_CR21","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1080\/00016489850154829","volume":"118","author":"Murakami","year":"1998","unstructured":"Murakami S, Nakashiro Y, Mizobuchi M, Hato N, Honda N, Gyo K (1998) Varicella-zoster virus distribution in Ramsay Hunt syndrome revealed by polymerase chain reaction. Acta Otolaryngol 118:145\u2013149","journal-title":"Acta Otolaryngol"},{"key":"202_CR22","doi-asserted-by":"crossref","first-page":"583","DOI":"10.3109\/00365548809035658","volume":"20","author":"Peterslund","year":"1988","unstructured":"Peterslund NA (1988) Herpes zoster associated encephalitis: clinical findings and acyclovir treatment. Scand J Infect Dis 20:583\u2013592","journal-title":"Scand J Infect Dis"},{"key":"202_CR23","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1515\/jpme.1994.22.1.65","volume":"22","author":"Puchhammer-St\u00f6ckl","year":"1994","unstructured":"Puchhammer-St\u00f6ckl E, Kunz C, Wagner G, Enders G (1994) Detection of varicella zoster virus (VZV) DNA in fetal tissue by polymerase chain reaction. J Perinat Med 22:65\u201369","journal-title":"J Perinat Med"},{"key":"202_CR24","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1128\/jcm.29.7.1513-1516.1991","volume":"29","author":"Puchhammer-St\u00f6ckl","year":"1991","unstructured":"Puchhammer-St\u00f6ckl E, Popow-Kraupp T, Heinz FX, Mandl CW, Kunz C (1991) Detection of varicella-zoster virus DNA by polymerase chain reaction in the cerebrospinal fluid of patients suffering from neurological complications associated with chicken pox or herpes zoster. J Clin Microbiol 29:1513\u20131516","journal-title":"J Clin Microbiol"},{"key":"202_CR25","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1128\/JCM.37.5.1352-1355.1999","volume":"37","author":"Read","year":"1999","unstructured":"Read SJ, Kurtz JB (1999) Laboratory diagnosis of common viral infections of the central nervous system by using a single multiplex PCR screening assay. J Clin Microbiol 37:1352\u20131355","journal-title":"J Clin Microbiol"}],"container-title":["Medical Microbiology and Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00430-003-0202-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00430-003-0202-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00430-003-0202-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00430-003-0202-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T00:58:00Z","timestamp":1659056280000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00430-003-0202-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3,2]]},"references-count":25,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["202"],"URL":"https:\/\/doi.org\/10.1007\/s00430-003-0202-1","relation":{},"ISSN":["0300-8584","1432-1831"],"issn-type":[{"value":"0300-8584","type":"print"},{"value":"1432-1831","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,3,2]]},"assertion":[{"value":"17 July 2003","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 March 2004","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}