{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:37:16Z","timestamp":1759333036191},"reference-count":64,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2011,1,30]],"date-time":"2011-01-30T00:00:00Z","timestamp":1296345600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Microbiol Immunol"],"published-print":{"date-parts":[[2011,8]]},"DOI":"10.1007\/s00430-011-0184-3","type":"journal-article","created":{"date-parts":[[2011,1,29]],"date-time":"2011-01-29T07:09:45Z","timestamp":1296284985000},"page":"143-154","source":"Crossref","is-referenced-by-count":11,"title":["Analysis of Chlamydia pneumoniae infection in mononuclear cells by reverse transcription-PCR targeted to chlamydial gene transcripts"],"prefix":"10.1007","volume":"200","author":[{"given":"Laura","family":"Mannonen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eveliina","family":"Markkula","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirja","family":"Puolakkainen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,1,30]]},"reference":[{"key":"184_CR1","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1111\/j.1365-2958.2010.07241.x","volume":"77","author":"S Haider","year":"2010","unstructured":"Haider S, Wagner M, Schmid MC, Sixt BS, Christian JG, H\u00e4cker G, Pichler P, Mechtler K, M\u00fcller A, Baranyi C, Toenshoff ER, Montanaro J, Horn M (2010) Raman microspectroscopy reveals long-term extracellular activity of chlamydiae. Mol Microbiol 77:687\u2013700","journal-title":"Mol Microbiol"},{"issue":"Suppl 1","key":"184_CR2","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/0163-4453(92)91913-V","volume":"25","author":"P Saikku","year":"1992","unstructured":"Saikku P (1992) The epidemiology and significance of Chlamydia pneumoniae. J Infect 25(Suppl 1):27\u201334","journal-title":"J Infect"},{"key":"184_CR3","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/nrmicro796","volume":"2","author":"LA Campbell","year":"2004","unstructured":"Campbell LA, Kuo CC (2004) Chlamydia pneumoniae\u2014an infectious risk factor for atherosclerosis? Nat Rev Microbiol 2:23\u201332","journal-title":"Nat Rev Microbiol"},{"key":"184_CR4","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1001\/jama.266.2.225","volume":"266","author":"DL Hahn","year":"1991","unstructured":"Hahn DL, Dodge RW, Golubjatnikov R (1991) Association of Chlamydia pneumoniae (strain TWAR) infection with wheezing, asthmatic bronchitis, and adult-onset asthma. JAMA 266:225\u2013230","journal-title":"JAMA"},{"key":"184_CR5","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/S0140-6736(88)90741-6","volume":"2","author":"P Saikku","year":"1988","unstructured":"Saikku P, Leinonen M, Mattila K, Ekman MR, Nieminen MS, M\u00e4kel\u00e4 PH, Huttunen JK, Valtonen V (1988) Serological evidence of an association of a novel Chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction. Lancet 2:983\u2013986","journal-title":"Lancet"},{"key":"184_CR6","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1615\/CritRevImmunol.v29.i4.10","volume":"29","author":"KW Beagley","year":"2009","unstructured":"Beagley KW, Huston WM, Hansbro PM, Timms P (2009) Chlamydial infection of immune cells: altered function and implications for disease. Crit Rev Immunol 29:275\u2013305","journal-title":"Crit Rev Immunol"},{"key":"184_CR7","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1086\/517452","volume":"178","author":"J Boman","year":"1998","unstructured":"Boman J, S\u00f6derberg S, Forsberg J, Birgander LS, Allard A, Persson K, Jidell E, Kumlin U, Juto P, Waldenstr\u00f6m A, Wadell G (1998) High prevalence of Chlamydia pneumoniae DNA in peripheral blood mononuclear cells in patients with cardiovascular disease and in middle-aged blood donors. J Infect Dis 178:274\u2013277","journal-title":"J Infect Dis"},{"issue":"Suppl","key":"184_CR8","doi-asserted-by":"crossref","first-page":"S449","DOI":"10.1086\/315610","volume":"3","author":"M Maass","year":"2000","unstructured":"Maass M, Jahn J, Gieffers J, Dalhoff K, Katus HA, Solbach W (2000) Detection of Chlamydia pneumoniae within peripheral blood monocytes of patients with unstable angina or myocardial infarction. J Infect Dis 3(Suppl):S449\u2013S451","journal-title":"J Infect Dis"},{"issue":"5","key":"184_CR9","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1086\/596710","volume":"48","author":"SK West","year":"2009","unstructured":"West SK, Kohlhepp SJ, Jin R, Gleaves CA, Stamm W, Gilbert DN (2009) Detection of circulating Chlamydophila pneumoniae in patients with coronary artery disease and healthy control subjects. Clin Infect Dis 48(5):560\u2013567","journal-title":"Clin Infect Dis"},{"key":"184_CR10","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1161\/01.ATV.20.6.1417","volume":"20","author":"SE Epstein","year":"2000","unstructured":"Epstein SE, Zhu J, Burnett MS, Zhou YF, Vercellotti G, Hajjar D (2000) Infection and atherosclerosis: potential roles of pathogen burden and molecular mimicry. Arterioscler Thromb Vasc Biol 20:1417\u20131420","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"184_CR11","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1161\/hc3401.093153","volume":"104","author":"HA Lehr","year":"2001","unstructured":"Lehr HA, Sagban TA, Ihling C, Z\u00e4hringer U, Hungerer KD, Blumrich M, Reifenberg K, Bhakdi S (2001) Immunopathogenesis of atherosclerosis: endotoxin accelerates atherosclerosis in rabbits on hypercholesterolemic diet. Circulation 104:914\u2013920","journal-title":"Circulation"},{"key":"184_CR12","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1160\/TH03-12-0733","volume":"91","author":"S Bhakdi","year":"2004","unstructured":"Bhakdi S, Lackner KJ, Han SR, Torzewski M, Husmann M (2004) Beyond cholesterol: the enigma of atherosclerosis revisited. Thromb Haemost 91:639\u2013645","journal-title":"Thromb Haemost"},{"key":"184_CR13","doi-asserted-by":"crossref","first-page":"5423","DOI":"10.1128\/IAI.69.9.5423-5429.2001","volume":"69","author":"GI Byrne","year":"2001","unstructured":"Byrne GI, Ouellette SP, Wang Z, Rao JP, Lu L, Beatty WL, Hudson AP (2001) Chlamydia pneumoniae expresses genes required for DNA replication but not cytokinesis during persistent infection of HEp-2 cells. Infect Immun 69:5423\u20135429","journal-title":"Infect Immun"},{"key":"184_CR14","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.micpath.2003.09.001","volume":"36","author":"L Mannonen","year":"2004","unstructured":"Mannonen L, Kamping E, Penttil\u00e4 T, Puolakkainen M (2004) IFN-\u03b3 induced persistent Chlamydia pneumoniae infection in HL and Mono Mac 6 cells: characterization by real-time quantitative PCR and culture. Microb Pathog 36:41\u201350","journal-title":"Microb Pathog"},{"key":"184_CR15","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s00428-008-0629-2","volume":"453","author":"YV Bobryshev","year":"2008","unstructured":"Bobryshev YV, Killingsworth MC, Tran D, Lord R (2008) Amalgamation of Chlamydia pneumoniae inclusions with lipid droplets in foam cells in human atherosclerotic plaque. Virchows Arch 453:69\u201377","journal-title":"Virchows Arch"},{"key":"184_CR16","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1046\/j.1462-5822.2001.00125.x","volume":"3","author":"HM Al-Younes","year":"2001","unstructured":"Al-Younes HM, Rudel T, Brinkmann V, Szczepek AJ, Meyer TF (2001) Low iron availability modulates the course of Chlamydia pneumoniae infection. Cell Microbiol 3:427\u2013437","journal-title":"Cell Microbiol"},{"key":"184_CR17","doi-asserted-by":"crossref","first-page":"3998","DOI":"10.1073\/pnas.90.9.3998","volume":"90","author":"WL Beatty","year":"1993","unstructured":"Beatty WL, Byrne GI, Morrison RP (1993) Morphologic and antigenic characterization of interferon \u03b3-mediated persistent Chlamydia trachomatis infection in vitro. Proc Natl Acad Sci USA 90:3998\u20134002","journal-title":"Proc Natl Acad Sci USA"},{"key":"184_CR18","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1007\/BF00521290","volume":"133","author":"RB Clark","year":"1982","unstructured":"Clark RB, Schatzki PF, Dalton HP (1982) Ultrastructural analysis of the effects of erythromycin on the morphology and developmental cycle of Chlamydia trachomatis HAR-13. Arch Microbiol 133:278\u2013282","journal-title":"Arch Microbiol"},{"key":"184_CR19","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1574-6968.1993.tb05958.x","volume":"106","author":"AM Coles","year":"1993","unstructured":"Coles AM, Reynolds DJ, Harper A, Devitt A, Pearce JH (1993) Low-nutrient induction of abnormal chlamydial development: a novel component of chlamydial pathogenesis? FEMS Microbiol Lett 106:193\u2013200","journal-title":"FEMS Microbiol Lett"},{"key":"184_CR20","doi-asserted-by":"crossref","first-page":"2268","DOI":"10.1128\/AAC.43.9.2268","volume":"43","author":"A Kutlin","year":"1999","unstructured":"Kutlin A, Roblin PM, Hammerschlag MR (1999) In vitro activities of azithromycin and ofloxacin against Chlamydia pneumoniae in a continuous-infection model. Antimicrob Agents Chemother 43:2268\u20132272","journal-title":"Antimicrob Agents Chemother"},{"key":"184_CR21","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1128\/iai.30.3.874-883.1980","volume":"30","author":"JW Moulder","year":"1980","unstructured":"Moulder JW, Levy NJ, Schulman LP (1980) Persistent infection of mouse fibroblasts (L cells) with Chlamydia psittaci: evidence for a cryptic chlamydial form. Infect Immun 30:874\u2013883","journal-title":"Infect Immun"},{"key":"184_CR22","doi-asserted-by":"crossref","first-page":"4872","DOI":"10.1128\/IAI.64.11.4872-4875.1996","volume":"64","author":"M Heinemann","year":"1996","unstructured":"Heinemann M, Susa M, Simnacher U, Marre R, Essig A (1996) Growth of Chlamydia pneumoniae induces cytokine production and expression of CD14 in a human monocytic cell line. Infect Immun 64:4872\u20134875","journal-title":"Infect Immun"},{"key":"184_CR23","doi-asserted-by":"crossref","first-page":"7039","DOI":"10.1128\/IAI.69.11.7039-7045.2001","volume":"69","author":"C Wahl","year":"2001","unstructured":"Wahl C, Oswald F, Simnacher U, Weiss S, Marre R, Essig A (2001) Survival of Chlamydia pneumoniae-infected Mono Mac 6 cells is dependent on NF-\u03baB binding activity. Infect Immun 69:7039\u20137045","journal-title":"Infect Immun"},{"key":"184_CR24","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1097\/00006454-199602000-00018","volume":"15","author":"K Numazaki","year":"1996","unstructured":"Numazaki K, Chiba S (1996) Serum \u03b3-interferon in patients with pneumonia caused by Chlamydia pneumoniae. Pediatr Infect Dis J 15:174\u2013175","journal-title":"Pediatr Infect Dis J"},{"key":"184_CR25","doi-asserted-by":"crossref","first-page":"5113","DOI":"10.1128\/IAI.66.11.5113-5118.1998","volume":"66","author":"JM Penttil\u00e4","year":"1998","unstructured":"Penttil\u00e4 JM, Anttila M, Puolakkainen M, Laurila A, Varkila K, Sarvas M, M\u00e4kel\u00e4 PH, Rautonen N (1998) Local immune responses to Chlamydia pneumoniae in the lungs of BALB\/c mice during primary infection and reinfection. Infect Immun 66:5113\u20135118","journal-title":"Infect Immun"},{"key":"184_CR26","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1006\/mpat.2000.0435","volume":"30","author":"S Mathews","year":"2001","unstructured":"Mathews S, George C, Flegg C, Stenzel D, Timms P (2001) Differential expression of ompA, ompB, pyk, nlpD and Cpn0585 genes between normal and interferon-\u03b3 treated cultures of Chlamydia pneumoniae. Microb Pathog 30:337\u2013345","journal-title":"Microb Pathog"},{"key":"184_CR27","doi-asserted-by":"crossref","first-page":"e83","DOI":"10.1371\/journal.ppat.0030083","volume":"3","author":"AP M\u00e4urer","year":"2007","unstructured":"M\u00e4urer AP, Mehlitz A, Mollenkopf HJ, Meyer TF (2007) Gene expression profiles of Chlamydophila pneumoniae during the developmental cycle and iron depletion-mediated persistence. PLoS Pathog 3:e83","journal-title":"PLoS Pathog"},{"key":"184_CR28","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1111\/j.1365-2958.2006.05465.x","volume":"62","author":"SP Ouellette","year":"2006","unstructured":"Ouellette SP, Hatch TP, AbdelRahman YM, Rose LA, Belland RJ, Byrne GI (2006) Global transcriptional upregulation in the absence of increased translation in Chlamydia during IFN\u03b3-mediated host cell tryptophan starvation. Mol Microbiol 62:1387\u20131401","journal-title":"Mol Microbiol"},{"key":"184_CR29","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.micinf.2005.05.018","volume":"8","author":"A Polkinghorne","year":"2005","unstructured":"Polkinghorne A, Hogan RJ, Vaughan L, Summersgill JT, Timms P (2005) Differential expression of chlamydial signal transduction genes in normal and interferon \u03b3-induced persistent Chlamydophila pneumoniae infections. Microbes Infect 8:61\u201372","journal-title":"Microbes Infect"},{"key":"184_CR30","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.1128\/IAI.71.5.2555-2562.2003","volume":"71","author":"A Slepenkin","year":"2003","unstructured":"Slepenkin A, Motin V, de la Maza LM, Peterson EM (2003) Temporal expression of type III secretion genes of Chlamydia pneumoniae. Infect Immun 71:2555\u20132562","journal-title":"Infect Immun"},{"key":"184_CR31","first-page":"27","volume":"42","author":"P Timms","year":"2009","unstructured":"Timms P, Good D, Wan C, Theodoropoulos C, Mukhopadhyay S, Summersgill J, Mathews S (2009) Differential transcriptional responses between the interferon-gamma-induction and iron-limitation models of persistence for Chlamydia pneumoniae. J Microbiol Immunol Infect 42:27\u201337","journal-title":"J Microbiol Immunol Infect"},{"key":"184_CR32","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1128\/IAI.67.3.1445-1449.1999","volume":"67","author":"S Airenne","year":"1999","unstructured":"Airenne S, Surcel HM, Alak\u00e4rpp\u00e4 H, Laitinen K, Paavonen J, Saikku P, Laurila A (1999) Chlamydia pneumoniae infection in human monocytes. Infect Immun 67:1445\u20131449","journal-title":"Infect Immun"},{"key":"184_CR33","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1161\/01.CIR.103.3.351","volume":"103","author":"J Gieffers","year":"2001","unstructured":"Gieffers J, F\u00fcllgraf H, Jahn J, Klinger M, Dalhoff K, Katus HA, Solbach W, Maass M (2001) Chlamydia pneumoniae infection in circulating human monocytes is refractory to antibiotic treatment. Circulation 103:351\u2013356","journal-title":"Circulation"},{"key":"184_CR34","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1086\/368168","volume":"187","author":"S Haranaga","year":"2003","unstructured":"Haranaga S, Yamaguchi H, Ikejima H, Friedman H, Yamamoto Y (2003) Chlamydia pneumoniae infection of alveolar macrophages: a model. J Infect Dis 187:1107\u20131115","journal-title":"J Infect Dis"},{"key":"184_CR35","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1111\/j.1574-6968.2008.01446.x","volume":"29","author":"A Klos","year":"2009","unstructured":"Klos A, Thalmann J, Peters J, G\u00e9rard HC, Hudson AP (2009) The transcript profile of persistent Chlamydophila (Chlamydia) pneumoniae in vitro depends on the means by which persistence is induced. FEMS Microbiol Lett 29:120\u2013126","journal-title":"FEMS Microbiol Lett"},{"key":"184_CR36","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1046\/j.1365-2958.1997.4701834.x","volume":"25","author":"RC Hsia","year":"1997","unstructured":"Hsia RC, Pannekoek Y, Ingerowski E, Bavoil PM (1997) Type III secretion genes identify a putative virulence locus of Chlamydia. Mol Microbiol 25:351\u2013359","journal-title":"Mol Microbiol"},{"key":"184_CR37","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1126\/science.282.5389.754","volume":"282","author":"RS Stephens","year":"1998","unstructured":"Stephens RS, Kalman S, Lammel C, Fan J, Marathe R, Aravind L, Mitchell W, Olinger L, Tatusov RL, Zhao Q, Koonin EV, Davis RW (1998) Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis. Science 282:754\u2013759","journal-title":"Science"},{"key":"184_CR38","doi-asserted-by":"crossref","first-page":"10166","DOI":"10.1073\/pnas.0402829101","volume":"101","author":"DR Clifton","year":"2004","unstructured":"Clifton DR, Fields KA, Grieshaber SS, Dooley CA, Fischer ER, Mead DJ, Carabeo RA, Hackstadt T (2004) A chlamydial type III translocated protein is tyrosine-phosphorylated at the site of entry and associated with recruitment of actin. Proc Natl Acad Sci USA 101:10166\u201310171","journal-title":"Proc Natl Acad Sci USA"},{"key":"184_CR39","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s00430-003-0206-x","volume":"193","author":"R Lugert","year":"2004","unstructured":"Lugert R, Kuhns M, Polch T, Gross U (2004) Expression and localization of type III secretion-related proteins of Chlamydia pneumoniae. Med Microbiol Immunol 193:163\u2013171","journal-title":"Med Microbiol Immunol"},{"key":"184_CR40","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s00430-008-0097-y","volume":"197","author":"N M\u00fcller","year":"2008","unstructured":"M\u00fcller N, Sattelmacher F, Lugert R, Gross U (2008) Characterization and intracellular localization of putative Chlamydia pneumoniae effector proteins. Med Microbiol Immunol 197:387\u2013396","journal-title":"Med Microbiol Immunol"},{"key":"184_CR41","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1111\/j.1365-2958.2005.04647.x","volume":"56","author":"A Subtil","year":"2005","unstructured":"Subtil A, Delevoye C, Bala\u00f1\u00e1 ME, Tastevin L, Perrinet S, Dautry-Varsat A (2005) A directed screen for chlamydial proteins secreted by a type III mechanism identifies a translocated protein and numerous other new candidates. Mol Microbiol 56:1636\u20131647","journal-title":"Mol Microbiol"},{"key":"184_CR42","doi-asserted-by":"crossref","first-page":"3478","DOI":"10.1128\/IAI.00023-07","volume":"75","author":"A Slepenkin","year":"2007","unstructured":"Slepenkin A, Enquist PA, H\u00e4gglund U, de la Maza LM, Elofsson M, Peterson EM (2007) Reversal of the antichlamydial activity of putative type III secretion inhibitors by iron. Infect Immun 75:3478\u20133489","journal-title":"Infect Immun"},{"key":"184_CR43","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1128\/JCM.28.5.938-940.1990","volume":"28","author":"LD Cles","year":"1990","unstructured":"Cles LD, Stamm WE (1990) Use of HL cells for improved isolation and passage of Chlamydia pneumoniae. J Clin Microbiol 28:938\u2013940","journal-title":"J Clin Microbiol"},{"key":"184_CR44","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1093\/clinids\/17.3.420","volume":"17","author":"MR Ekman","year":"1993","unstructured":"Ekman MR, Grayston JT, Visakorpi R, Kleemola M, Kuo CC, Saikku P (1993) An epidemic of infections due to Chlamydia pneumoniae in military conscripts. Clin Infect Dis 17:420\u2013425","journal-title":"Clin Infect Dis"},{"key":"184_CR45","doi-asserted-by":"crossref","first-page":"2801","DOI":"10.1128\/IAI.63.7.2801-2803.1995","volume":"63","author":"JT Summersgill","year":"1995","unstructured":"Summersgill JT, Sahney NN, Gaydos CA, Quinn TC, Ramirez JA (1995) Inhibition of Chlamydia pneumoniae growth in HEp-2 cells pretreated with gamma interferon and tumor necrosis factor alpha. Infect Immun 63:2801\u20132803","journal-title":"Infect Immun"},{"key":"184_CR46","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1086\/510314","volume":"195","author":"L Mannonen","year":"2007","unstructured":"Mannonen L, Nikula T, Haveri A, Reinikainen A, Vuola JM, Lahesmaa R, Puolakkainen M (2007) Up-regulation of host cell genes during interferon-\u03b3-induced persistent Chlamydia pneumoniae infection in HL cells. J Infect Dis 195:212\u2013219","journal-title":"J Infect Dis"},{"key":"184_CR47","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1128\/CDLI.10.3.367-375.2003","volume":"10","author":"U Airaksinen","year":"2003","unstructured":"Airaksinen U, Penttil\u00e4 T, Wahlstr\u00f6m E, Vuola JM, Puolakkainen M, Sarvas M (2003) Production of Chlamydia pneumoniae proteins in Bacillus subtilis and their use in characterizing immune responses in the experimental infection model. Clin Diagn Lab Immunol 10:367\u2013375","journal-title":"Clin Diagn Lab Immunol"},{"key":"184_CR48","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1128\/JB.01034-06","volume":"189","author":"PS Hefty","year":"2007","unstructured":"Hefty PS, Stephens RS (2007) Chlamydial type III secretion system is encoded on ten operons preceded by sigma 70-like promoter elements. J Bacteriol 189:198\u2013206","journal-title":"J Bacteriol"},{"key":"184_CR49","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1128\/IAI.72.4.1843-1855.2004","volume":"72","author":"RJ Hogan","year":"2004","unstructured":"Hogan RJ, Mathews SA, Mukhopadhyay S, Summersgill JT, Timms P (2004) Chlamydial persistence: beyond the biphasic paradigm. Infect Immun 72:1843\u20131855","journal-title":"Infect Immun"},{"key":"184_CR50","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1046\/j.1462-5822.2000.00029.x","volume":"2","author":"JP Bannantine","year":"2000","unstructured":"Bannantine JP, Griffiths RS, Viratyosin W, Brown WJ, Rockey DD (2000) A secondary structure motif predictive of protein localization to the chlamydial inclusion membrane. Cell Microbiol 2:35\u201347","journal-title":"Cell Microbiol"},{"key":"184_CR51","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/S0966-842X(97)01061-5","volume":"5","author":"T Hackstadt","year":"1997","unstructured":"Hackstadt T, Fischer ER, Scidmore MA, Rockey DD, Heinzen RA (1997) Origins and functions of the chlamydial inclusion. Trends Microbiol 5:288\u2013293","journal-title":"Trends Microbiol"},{"key":"184_CR52","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1046\/j.1462-5822.1999.00012.x","volume":"1","author":"T Hackstadt","year":"1999","unstructured":"Hackstadt T, Scidmore-Carlson MA, Shaw EI, Fischer ER (1999) The Chlamydia trachomatis IncA protein is required for homotypic vesicle fusion. Cell Microbiol 1:119\u2013130","journal-title":"Cell Microbiol"},{"key":"184_CR53","doi-asserted-by":"crossref","first-page":"e7375","DOI":"10.1371\/journal.pone.0007375","volume":"4","author":"F Paumet","year":"2009","unstructured":"Paumet F, Wesolowski J, Garcia-Diaz A, Delevoye C, Aulner N, Shuman HA, Subtil A, Rothman JE (2009) Intracellular bacteria encode inhibitory SNARE-like proteins. PLoS ONE 4:e7375","journal-title":"PLoS ONE"},{"key":"184_CR54","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1046\/j.1462-5822.2000.00059.x","volume":"2","author":"PB Wyrick","year":"2000","unstructured":"Wyrick PB (2000) Intracellular survival by Chlamydia. Cell Microbiol 2:275\u2013282","journal-title":"Cell Microbiol"},{"key":"184_CR55","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1099\/13500872-141-10-2489","volume":"141","author":"MW Watson","year":"1995","unstructured":"Watson MW, Clarke IN, Everson JS, Lambden PR (1995) The CrP operon of Chlamydia psittaci and Chlamydia pneumoniae. Microbiology 141:2489\u20132497","journal-title":"Microbiology"},{"key":"184_CR56","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1046\/j.1462-5822.2003.00278.x","volume":"5","author":"D Heuer","year":"2003","unstructured":"Heuer D, Brinkmann V, Meyer TF, Szczepek AJ (2003) Expression and translocation of chlamydial protease during acute and persistent infection of the epithelial HEp-2 cells with Chlamydophila (Chlamydia) pneumoniae. Cell Microbiol 5:315\u2013322","journal-title":"Cell Microbiol"},{"key":"184_CR57","doi-asserted-by":"crossref","first-page":"3863","DOI":"10.1128\/IAI.72.7.3863-3868.2004","volume":"72","author":"F Dong","year":"2004","unstructured":"Dong F, Su H, Huang Y, Zhong Y, Zhong G (2004) Cleavage of host keratin 8 by a Chlamydia-secreted protease. Infect Immun 72:3863\u20133868","journal-title":"Infect Immun"},{"key":"184_CR58","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.chom.2008.05.018","volume":"4","author":"Y Kumar","year":"2008","unstructured":"Kumar Y, Valdivia RH (2008) Actin and intermediate filaments stabilize the Chlamydia trachomatis vacuole by forming dynamic structural scaffolds. Cell Host Microbe 4:159\u2013169","journal-title":"Cell Host Microbe"},{"key":"184_CR59","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0882-4010(02)00187-0","volume":"34","author":"RJ Hogan","year":"2003","unstructured":"Hogan RJ, Mathews SA, Kutlin A, Hammerschlag MR, Timms P (2003) Differential expression of genes encoding membrane proteins between acute and continuous Chlamydia pneumoniae infections. Microb Pathog 34:11\u201316","journal-title":"Microb Pathog"},{"key":"184_CR60","doi-asserted-by":"crossref","first-page":"3179","DOI":"10.1128\/JB.185.10.3179-3189.2003","volume":"185","author":"TL Nicholson","year":"2003","unstructured":"Nicholson TL, Olinger L, Chong K, Schoolnik G, Stephens RS (2003) Global stage-specific gene regulation during the developmental cycle of Chlamydia trachomatis. J Bacteriol 185:3179\u20133189","journal-title":"J Bacteriol"},{"key":"184_CR61","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s004300050082","volume":"187","author":"HC G\u00e9rard","year":"1998","unstructured":"G\u00e9rard HC, K\u00f6hler L, Branigan PJ, Zeidler H, Schumacher HR, Hudson AP (1998) Viability and gene expression in Chlamydia trachomatis during persistent infection of cultured human monocytes. Med Microbiol Immunol 187:115\u2013120","journal-title":"Med Microbiol Immunol"},{"key":"184_CR62","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1006\/mpat.1996.0103","volume":"22","author":"L Koehler","year":"1997","unstructured":"Koehler L, Nettelnbreker E, Hudson AP, Ott N, G\u00e9rard HC, Branigan PJ, Schumacher HR, Drommer W, Zeidler H (1997) Ultrastructural and molecular analyses of the persistence of Chlamydia trachomatis (serovar K) in human monocytes. Microb Pathog 22:133\u2013142","journal-title":"Microb Pathog"},{"key":"184_CR63","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1099\/00222615-38-4-278","volume":"38","author":"E Schmitz","year":"1993","unstructured":"Schmitz E, Nettelnbreker E, Zeidler H, Hammer M, Manor E, Wollenhaupt J (1993) Intracellular persistence of chlamydial major outer-membrane protein, lipopolysaccharide and ribosomal RNA after non-productive infection of human monocytes with Chlamydia trachomatis serovar K. J Med Microbiol 38:278\u2013285","journal-title":"J Med Microbiol"},{"key":"184_CR64","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.febslet.2007.01.013","volume":"581","author":"L Bailey","year":"2007","unstructured":"Bailey L, Gylfe A, Sundin C, Muschiol S, Elofsson M, Nordstr\u00f6m P, Henriques-Normark B, Lugert R, Waldenstr\u00f6m A, Wolf-Watz H, Bergstr\u00f6m S (2007) Small molecule inhibitors of type III secretion in Yersinia block the Chlamydia pneumoniae infection cycle. FEBS Lett 581:587\u2013595","journal-title":"FEBS Lett"}],"container-title":["Medical Microbiology and Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00430-011-0184-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00430-011-0184-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00430-011-0184-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T07:25:54Z","timestamp":1637220354000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00430-011-0184-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1,30]]},"references-count":64,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,8]]}},"alternative-id":["184"],"URL":"https:\/\/doi.org\/10.1007\/s00430-011-0184-3","relation":{},"ISSN":["0300-8584","1432-1831"],"issn-type":[{"value":"0300-8584","type":"print"},{"value":"1432-1831","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1,30]]}}}