{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T17:50:18Z","timestamp":1792259418485,"version":"4.4.0"},"reference-count":66,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2011,12,18]],"date-time":"2011-12-18T00:00:00Z","timestamp":1324166400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2011,12,18]],"date-time":"2011-12-18T00:00:00Z","timestamp":1324166400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Microbiol Immunol"],"published-print":{"date-parts":[[2012,5]]},"DOI":"10.1007\/s00430-011-0221-2","type":"journal-article","created":{"date-parts":[[2011,12,17]],"date-time":"2011-12-17T05:41:54Z","timestamp":1324100514000},"page":"189-200","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":150,"title":["Seroprevalence study in forestry workers from eastern Germany using novel genotype 3- and rat hepatitis E virus-specific immunoglobulin G ELISAs"],"prefix":"10.1007","volume":"201","author":[{"given":"Paul","family":"Dremsek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen J.","family":"Wenzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reimar","family":"Johne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Ziller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Hofmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin H.","family":"Groschup","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Werdermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Mohn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Dorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manfred","family":"Motz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Mertens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Jilg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rainer G.","family":"Ulrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,12,18]]},"reference":[{"issue":"Suppl 1","key":"221_CR1","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1111\/j.1440-1746.2010.06540.x","volume":"26","author":"R Aggarwal","year":"2011","unstructured":"Aggarwal R (2011) Hepatitis E: historical, contemporary and future perspectives. J Gastroenterol Hepatol 26(Suppl 1):72\u201382","journal-title":"J Gastroenterol Hepatol"},{"issue":"2","key":"221_CR2","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1017\/S0950268809990847","volume":"138","author":"HC Lewis","year":"2010","unstructured":"Lewis HC, Wichmann O, Duizer E (2010) Transmission routes and risk factors for autochthonous hepatitis E virus infection in Europe: a systematic review. Epidemiol Infect 138(2):145\u2013166","journal-title":"Epidemiol Infect"},{"issue":"6","key":"221_CR3","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1051\/vetres\/2010018","volume":"41","author":"N Pavio","year":"2010","unstructured":"Pavio N, Meng XJ, Renou C (2010) Zoonotic hepatitis E: animal reservoirs and emerging risks. Vet Res 41(6):46","journal-title":"Vet Res"},{"issue":"11","key":"221_CR4","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1016\/S1473-3099(08)70255-X","volume":"8","author":"HR Dalton","year":"2008","unstructured":"Dalton HR, Bendall R, Ijaz S, Banks M (2008) Hepatitis E: an emerging infection in developed countries. Lancet Infect Dis 8(11):698\u2013709","journal-title":"Lancet Infect Dis"},{"issue":"3","key":"221_CR5","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1016\/j.jhep.2007.12.008","volume":"48","author":"RH Purcell","year":"2008","unstructured":"Purcell RH, Emerson SU (2008) Hepatitis E: an emerging awareness of an old disease. J Hepatol 48(3):494\u2013503","journal-title":"J Hepatol"},{"key":"221_CR6","first-page":"851","volume-title":"Virus taxonomy. VIIIth report of the ICTV","author":"S Emerson","year":"2004","unstructured":"Emerson S, Anderson D, Arankalle A, Meng X, Purdy M, Schlauder G (2004) Hepevirus. In: Fauquet CM, Mayo MA, Maniloff J, Desselberger U, Ball LA (eds) Virus taxonomy. VIIIth report of the ICTV. Elsevier\/Academic Press, London, pp 851\u2013855"},{"key":"221_CR7","unstructured":"International Committee on Taxonomy of Viruses (2009) http:\/\/www.ictvonline.org\/virusTaxonomy.asp?version=2009"},{"issue":"43","key":"221_CR8","doi-asserted-by":"publisher","first-page":"33,175","DOI":"10.1074\/jbc.M110.106336","volume":"285","author":"L Xing","year":"2010","unstructured":"Xing L, Li TC, Mayazaki N, Simon MN, Wall JS, Moore M, Wang CY, Takeda N, Wakita T, Miyamura T, Cheng RH (2010) Structure of hepatitis E virion-sized particle reveals an RNA-dependent viral assembly pathway. J Biol Chem 285(43):33,175\u201333183","journal-title":"J Biol Chem"},{"key":"221_CR9","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1186\/1743-422X-6-58","volume":"6","author":"A Schielke","year":"2009","unstructured":"Schielke A, Sachs K, Lierz M, Appel B, Jansen A, Johne R (2009) Detection of hepatitis E virus in wild boars of rural and urban regions in Germany and whole genome characterization of an endemic strain. Virol J 6:58","journal-title":"Virol J"},{"issue":"1","key":"221_CR10","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.virusres.2011.02.011","volume":"161","author":"I Ahmad","year":"2011","unstructured":"Ahmad I, Holla RP, Jameel S (2011) Molecular virology of hepatitis E virus. Virus Res 161(1):47\u201358","journal-title":"Virus Res"},{"issue":"1","key":"221_CR11","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.virusres.2011.06.006","volume":"161","author":"Y Khudyakov","year":"2011","unstructured":"Khudyakov Y, Kamili S (2011) Serological diagnostics of hepatitis E virus infection. Virus Res 161(1):84\u201392","journal-title":"Virus Res"},{"issue":"1","key":"221_CR12","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1002\/rmv.482","volume":"16","author":"L Lu","year":"2006","unstructured":"Lu L, Li C, Hagedorn CH (2006) Phylogenetic analysis of global hepatitis E virus sequences: genetic diversity, subtypes and zoonosis. Rev Med Virol 16(1):5\u201336","journal-title":"Rev Med Virol"},{"issue":"3\u20134","key":"221_CR13","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/j.vetmic.2009.03.017","volume":"140","author":"XJ Meng","year":"2010","unstructured":"Meng XJ (2010) Hepatitis E virus: animal reservoirs and zoonotic risk. Vet Microbiol 140(3\u20134):256\u2013265","journal-title":"Vet Microbiol"},{"issue":"9381","key":"221_CR14","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1016\/S0140-6736(03)14025-1","volume":"362","author":"S Tei","year":"2003","unstructured":"Tei S, Kitajima N, Takahashi K, Mishiro S (2003) Zoonotic transmission of hepatitis E virus from deer to human beings. Lancet 362(9381):371\u2013373","journal-title":"Lancet"},{"issue":"1","key":"221_CR15","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1002\/jmv.20147","volume":"74","author":"S Tei","year":"2004","unstructured":"Tei S, Kitajima N, Ohara S, Inoue Y, Miki M, Yamatani T, Yamabe H, Mishiro S, Kinoshita Y (2004) Consumption of uncooked deer meat as a risk factor for hepatitis E virus infection: an age- and sex-matched case-control study. J Med Virol 74(1):67\u201370","journal-title":"J Med Virol"},{"issue":"1","key":"221_CR16","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.virusres.2011.01.016","volume":"161","author":"XJ Meng","year":"2011","unstructured":"Meng XJ (2011) From barnyard to food table: the omnipresence of hepatitis E virus and risk for zoonotic infection and food safety. Virus Res 161(1):23\u201330","journal-title":"Virus Res"},{"issue":"8","key":"221_CR17","doi-asserted-by":"publisher","first-page":"1345","DOI":"10.1007\/s00705-011-0988-x","volume":"156","author":"Y Sato","year":"2011","unstructured":"Sato Y, Sato H, Naka K, Furuya S, Tsukiji H, Kitagawa K, Sonoda Y, Usui T, Sakamoto H, Yoshino S, Shimizu Y, Takahashi M, Nagashima S, Jirintai, Nishizawa T, Okamoto H (2011) A nationwide survey of hepatitis E virus (HEV) infection in wild boars in Japan: identification of boar HEV strains of genotypes 3 and 4 and unrecognized genotypes. Arch Virol 156(8):1345\u20131358","journal-title":"Arch Virol"},{"issue":"Pt 4","key":"221_CR18","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1099\/vir.0.029470-0","volume":"92","author":"M Takahashi","year":"2011","unstructured":"Takahashi M, Nishizawa T, Sato H, Sato Y, Jirintai, Nagashima S, Okamoto H (2011) Analysis of the full-length genome of a hepatitis E virus isolate obtained from a wild boar in Japan that is classifiable into a novel genotype. J Gen Virol 92(Pt 4):902\u2013908","journal-title":"J Gen Virol"},{"issue":"8","key":"221_CR19","doi-asserted-by":"publisher","first-page":"1371","DOI":"10.1002\/jmv.21536","volume":"81","author":"C Zhao","year":"2009","unstructured":"Zhao C, Ma Z, Harrison TJ, Feng R, Zhang C, Qiao Z, Fan J, Ma H, Li M, Song A, Wang Y (2009) A novel genotype of hepatitis E virus prevalent among farmed rabbits in China. J Med Virol 81(8):1371\u20131379","journal-title":"J Med Virol"},{"issue":"Pt 3","key":"221_CR20","doi-asserted-by":"publisher","first-page":"750","DOI":"10.1099\/vir.0.016584-0","volume":"91","author":"R Johne","year":"2010","unstructured":"Johne R, Plenge-B\u00f6nig A, Hess M, Ulrich RG, Reetz J, Schielke A (2010) Detection of a novel hepatitis E-like virus in faeces of wild rats using a nested broad-spectrum RT-PCR. J Gen Virol 91(Pt 3):750\u2013758","journal-title":"J Gen Virol"},{"issue":"1\u20132","key":"221_CR21","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/S0378-1135(99)00067-X","volume":"68","author":"CJ Payne","year":"1999","unstructured":"Payne CJ, Ellis TM, Plant SL, Gregory AR, Wilcox GE (1999) Sequence data suggests big liver and spleen disease virus (BLSV) is genetically related to hepatitis E virus. Vet Microbiol 68(1\u20132):119\u2013125","journal-title":"Vet Microbiol"},{"issue":"Pt 10","key":"221_CR22","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1099\/0022-1317-82-10-2449","volume":"82","author":"G Haqshenas","year":"2001","unstructured":"Haqshenas G, Shivaprasad HL, Woolcock PR, Read DH, Meng XJ (2001) Genetic identification and characterization of a novel virus related to human hepatitis E virus from chickens with hepatitis-splenomegaly syndrome in the United States. J Gen Virol 82(Pt 10):2449\u20132462","journal-title":"J Gen Virol"},{"issue":"1\u20132","key":"221_CR23","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.vetmic.2010.03.014","volume":"145","author":"A Marek","year":"2010","unstructured":"Marek A, Bilic I, Prokofieva I, Hess M (2010) Phylogenetic analysis of avian hepatitis E virus samples from European and Australian chicken flocks supports the existence of a different genus within the Hepeviridae comprising at least three different genotypes. Vet Microbiol 145(1\u20132):54\u201361","journal-title":"Vet Microbiol"},{"issue":"9","key":"221_CR24","doi-asserted-by":"publisher","first-page":"1452","DOI":"10.3201\/eid1609.100444","volume":"16","author":"R Johne","year":"2010","unstructured":"Johne R, Heckel G, Plenge-B\u00f6nig A, Kindler E, Maresch C, Reetz J, Schielke A, Ulrich RG (2010) Novel hepatitis E virus genotype in Norway rats, Germany. Emerg Infect Dis 16(9):1452\u20131455","journal-title":"Emerg Infect Dis"},{"issue":"1\u20132","key":"221_CR25","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/j.virusres.2011.03.019","volume":"158","author":"W Batts","year":"2011","unstructured":"Batts W, Yun S, Hedrick R, Winton J (2011) A novel member of the family Hepeviridae from cutthroat trout (Oncorhynchus clarkii). Virus Res 158(1\u20132):116\u2013123","journal-title":"Virus Res"},{"issue":"1","key":"221_CR26","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1046\/j.1440-1746.2000.02006.x","volume":"15","author":"R Aggarwal","year":"2000","unstructured":"Aggarwal R, Krawczynski K (2000) Hepatitis E: an overview and recent advances in clinical and laboratory research. J Gastroenterol Hepatol 15(1):9\u201320","journal-title":"J Gastroenterol Hepatol"},{"issue":"3","key":"221_CR27","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/s15010-006-4132-x","volume":"34","author":"JC Preiss","year":"2006","unstructured":"Preiss JC, Plentz A, Engelmann E, Schneider T, Jilg W, Zeitz M, Duchmann R (2006) Autochthonous hepatitis E virus infection in Germany with sequence similarities to other European isolates. Infection 34(3):173\u2013175","journal-title":"Infection"},{"issue":"1","key":"221_CR28","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.jcv.2009.10.011","volume":"47","author":"S Brost","year":"2010","unstructured":"Brost S, Wenzel JJ, Ganten TM, Filser M, Flechtenmacher C, Boehm S, Astani A, Jilg W, Zeier M, Schnitzler P (2010) Sporadic cases of acute autochthonous hepatitis E virus infection in Southwest Germany. J Clin Virol 47(1):89\u201392","journal-title":"J Clin Virol"},{"issue":"1","key":"221_CR29","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1055\/s-0029-1245767","volume":"49","author":"R Veitt","year":"2011","unstructured":"Veitt R, Reichardt M, Wenzel J, Jilg W (2011) Autochthonous hepatitis E-virus infection as cause of acute hepatitis in Germany\u2014a case report. Z Gastroenterol 49(1):42\u201346","journal-title":"Z Gastroenterol"},{"issue":"12","key":"221_CR30","doi-asserted-by":"publisher","first-page":"1732","DOI":"10.1086\/593211","volume":"198","author":"O Wichmann","year":"2008","unstructured":"Wichmann O, Schimanski S, Koch J, Kohler M, Rothe C, Plentz A, Jilg W, Stark K (2008) Phylogenetic and case-control study on hepatitis E virus infection in Germany. J Infect Dis 198(12):1732\u20131741","journal-title":"J Infect Dis"},{"issue":"5","key":"221_CR31","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1136\/gut.2008.165571","volume":"58","author":"P le Coutre","year":"2009","unstructured":"le Coutre P, Meisel H, Hofmann J, R\u00f6cken C, Vuong GL, Neuburger S, Hemmati PG, D\u00f6rken B, Arnold R (2009) Reactivation of hepatitis E infection in a patient with acute lymphoblastic leukaemia after allogeneic stem cell transplantation. Gut 58(5):699\u2013702","journal-title":"Gut"},{"issue":"1","key":"221_CR32","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1002\/lt.21958","volume":"16","author":"S Pischke","year":"2010","unstructured":"Pischke S, Suneetha PV, Baechlein C, Barg-Hock H, Heim A, Kamar N, Schlue J, Strassburg CP, Lehner F, Raupach R, Bremer B, Magerstedt P, Cornberg M, Seehusen F, Baumgaertner W, Klempnauer J, Izopet J, Manns MP, Grummer B, Wedemeyer H (2010) Hepatitis E virus infection as a cause of graft hepatitis in liver transplant recipients. Liver Transpl 16(1):74\u201382","journal-title":"Liver Transpl"},{"key":"221_CR33","doi-asserted-by":"crossref","unstructured":"Schlosser B, Stein A, Neuhaus R, Pahl S, Ramez B, Kr\u00fcger DH, Berg T, Hofmann J (2011) Liver transplant from a donor with occult HEV infection induced chronic hepatitis and cirrhosis in the recipient. J Hepatol (in press)","DOI":"10.1016\/j.jhep.2011.06.021"},{"issue":"3\u20134","key":"221_CR34","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1016\/j.vetmic.2007.10.030","volume":"128","author":"S Kaci","year":"2008","unstructured":"Kaci S, N\u00f6ckler K, Johne R (2008) Detection of hepatitis E virus in archived German wild boar serum samples. Vet Microbiol 128(3\u20134):380\u2013385","journal-title":"Vet Microbiol"},{"issue":"3\u20134","key":"221_CR35","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1016\/j.vetmic.2009.06.032","volume":"139","author":"C Adlhoch","year":"2009","unstructured":"Adlhoch C, Wolf A, Meisel H, Kaiser M, Ellerbrok H, Pauli G (2009) High HEV presence in four different wild boar populations in East and West Germany. Vet Microbiol 139(3\u20134):270\u2013278","journal-title":"Vet Microbiol"},{"issue":"1","key":"221_CR36","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.jcv.2011.06.006","volume":"52","author":"JJ Wenzel","year":"2011","unstructured":"Wenzel JJ, Preiss J, Schemmerer M, Huber B, Plentz A, Jilg W (2011) Detection of hepatitis E virus (HEV) from porcine livers in Southeastern Germany and high sequence homology to human HEV isolates. J Clin Virol 52(1):50\u201354","journal-title":"J Clin Virol"},{"issue":"4","key":"221_CR37","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1007\/s00430-011-0203-4","volume":"200","author":"M Mertens","year":"2011","unstructured":"Mertens M, Hofmann J, Petraityte-Burneikiene R, Ziller M, Sasnauskas K, Friedrich R, Niederstrasser O, Kr\u00fcger DH, Groschup MH, Petri E, Werdermann S, Ulrich RG (2011) Seroprevalence study in forestry workers of a non-endemic region in eastern Germany reveals infections by Tula and Dobrava-Belgrade hantaviruses. Med Microbiol Immunol 200(4):263\u2013268","journal-title":"Med Microbiol Immunol"},{"issue":"2","key":"221_CR38","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/s00430-009-0106-9","volume":"198","author":"M Mertens","year":"2009","unstructured":"Mertens M, W\u00f6lfel R, Ullrich K, Yoshimatsu K, Blumhardt J, R\u00f6mer I, Esser J, Schmidt-Chanasit J, Groschup MH, Dobler G, Essbauer SS, Ulrich RG (2009) Seroepidemiological study in a Puumala virus outbreak area in South-East Germany. Med Microbiol Immunol 198(2):83\u201391","journal-title":"Med Microbiol Immunol"},{"key":"221_CR39","volume-title":"R: a language and environment for statistical computing","author":"R Development Core Team","year":"2011","unstructured":"R Development Core Team (2011) R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna"},{"issue":"Suppl 3","key":"221_CR40","doi-asserted-by":"publisher","first-page":"S360","DOI":"10.1046\/j.1440-1746.17.s3.28.x","volume":"17","author":"A Obriadina","year":"2002","unstructured":"Obriadina A, Meng JH, Ulanova T, Trinta K, Burkov A, Fields HA, Khudyakov YE (2002) A new enzyme immunoassay for the detection of antibody to hepatitis E virus. J Gastroenterol Hepatol 17(Suppl 3):S360\u2013S364","journal-title":"J Gastroenterol Hepatol"},{"issue":"5","key":"221_CR41","first-page":"593","volume":"12","author":"HY Chen","year":"2005","unstructured":"Chen HY, Lu Y, Howard T, Anderson D, Fong PY, Hu WP, Chia CP, Guan M (2005) Comparison of a new immunochromatographic test to enzyme-linked immunosorbent assay for rapid detection of immunoglobulin M antibodies to hepatitis E virus in human sera. Clin Diagn Lab Immunol 12(5):593\u2013598","journal-title":"Clin Diagn Lab Immunol"},{"issue":"8","key":"221_CR42","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1128\/CVI.00186-07","volume":"15","author":"WP Hu","year":"2008","unstructured":"Hu WP, Lu Y, Precioso NA, Chen HY, Howard T, Anderson D, Guan M (2008) Double-antigen enzyme-linked immunosorbent assay for detection of hepatitis E virus-specific antibodies in human or swine sera. Clin Vaccine Immunol 15(8):1151\u20131157","journal-title":"Clin Vaccine Immunol"},{"issue":"11","key":"221_CR43","doi-asserted-by":"crossref","first-page":"7067","DOI":"10.1128\/jvi.68.11.7067-7074.1994","volume":"68","author":"YE Khudyakov","year":"1994","unstructured":"Khudyakov YE, Favorov MO, Khudyakova NS, Cong ME, Holloway BP, Padhye N, Lambert SB, Jue DL, Fields HA (1994) Artificial mosaic protein containing antigenic epitopes of hepatitis E virus. J Virol 68(11):7067\u20137074","journal-title":"J Virol"},{"issue":"17","key":"221_CR44","doi-asserted-by":"publisher","first-page":"8011","DOI":"10.1128\/JVI.74.17.8011-8017.2000","volume":"74","author":"MA Riddell","year":"2000","unstructured":"Riddell MA, Li F, Anderson DA (2000) Identification of immunodominant and conformational epitopes in the capsid protein of hepatitis E virus by using monoclonal antibodies. J Virol 74(17):8011\u20138017","journal-title":"J Virol"},{"issue":"31","key":"221_CR45","doi-asserted-by":"publisher","first-page":"12,986","DOI":"10.1073\/pnas.0903699106","volume":"106","author":"T Yamashita","year":"2009","unstructured":"Yamashita T, Mori Y, Miyazaki N, Cheng RH, Yoshimura M, Unno H, Shima R, Moriishi K, Tsukihara T, Li TC, Takeda N, Miyamura T, Matsuura Y (2009) Biological and immunological characteristics of hepatitis E virus-like particles based on the crystal structure. Proc Natl Acad Sci USA 106(31):12,986\u201312991","journal-title":"Proc Natl Acad Sci USA"},{"issue":"4","key":"221_CR46","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1002\/(SICI)1096-9071(200004)60:4<379::AID-JMV3>3.0.CO;2-X","volume":"60","author":"F Li","year":"2000","unstructured":"Li F, Riddell MA, Seow HF, Takeda N, Miyamura T, Anderson DA (2000) Recombinant subunit ORF2.1 antigen and induction of antibody against immunodominant epitopes in the hepatitis E virus capsid protein. J Med Virol 60(4):379\u2013386","journal-title":"J Med Virol"},{"issue":"9","key":"221_CR47","doi-asserted-by":"crossref","first-page":"2863","DOI":"10.1128\/JCM.37.9.2863-2871.1999","volume":"37","author":"YE Khudyakov","year":"1999","unstructured":"Khudyakov YE, Lopareva EN, Jue DL, Crews TK, Thyagarajan SP, Fields HA (1999) Antigenic domains of the open reading frame 2-encoded protein of hepatitis E virus. J Clin Microbiol 37(9):2863\u20132871","journal-title":"J Clin Microbiol"},{"issue":"20","key":"221_CR48","doi-asserted-by":"publisher","first-page":"2578","DOI":"10.1016\/j.vaccine.2003.12.017","volume":"22","author":"YH Zhou","year":"2004","unstructured":"Zhou YH, Purcell RH, Emerson SU (2004) An ELISA for putative neutralizing antibodies to hepatitis E virus detects antibodies to genotypes 1, 2, 3, and 4. Vaccine 22(20):2578\u20132585","journal-title":"Vaccine"},{"issue":"6","key":"221_CR49","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1111\/j.1365-2893.2006.00801.x","volume":"14","author":"VA Arankalle","year":"2007","unstructured":"Arankalle VA, Lole KS, Deshmukh TM, Chobe LP, Gandhe SS (2007) Evaluation of human (genotype 1) and swine (genotype 4)-ORF2-based ELISAs for anti-HEV IgM and IgG detection in an endemic country and search for type 4 human HEV infections. J Viral Hepat 14(6):435\u2013445","journal-title":"J Viral Hepat"},{"issue":"10","key":"221_CR50","doi-asserted-by":"publisher","first-page":"3276","DOI":"10.1128\/JCM.00750-09","volume":"47","author":"J de Oya","year":"2009","unstructured":"de Oya J, Galindo I, Giron\u00e9s O, Duizer E, Escribano JM, Saiz JC (2009) Serological immunoassay for detection of hepatitis E virus on the basis of genotype 3 open reading frame 2 recombinant proteins produced in Trichoplusia in larvae. J Clin Microbiol 47(10):3276\u20133282","journal-title":"J Clin Microbiol"},{"key":"221_CR51","first-page":"856","volume-title":"Mikrobiologische Diagnostik","author":"H Meisel","year":"2009","unstructured":"Meisel H (2009) Hepatitis-E-Virus. In: Neumeister B, Braun R, Kimmig P (eds) Mikrobiologische Diagnostik. Georg Thieme Verlag, Stuttgart, pp 856\u2013861"},{"key":"221_CR52","doi-asserted-by":"crossref","unstructured":"Krumbholz A, Mohn U, Lange J, Motz M, Wenzel JJ, Jilg W, Walther M, Straube E, Wutzler P, Zell R (2011) Prevalence of hepatitis E virus-specific antibodies in humans with occupational exposure to pigs. Med Microbiol Immunol (in press)","DOI":"10.1007\/s00430-011-0210-5"},{"issue":"8","key":"221_CR53","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.1086\/591970","volume":"47","author":"PB Christensen","year":"2008","unstructured":"Christensen PB, Engle RE, Hjort C, Homburg KM, Vach W, Georgsen J, Purcell RH (2008) Time trend of the prevalence of hepatitis E antibodies among farmers and blood donors: a potential zoonosis in Denmark. Clin Infect Dis 47(8):1026\u20131031","journal-title":"Clin Infect Dis"},{"issue":"8","key":"221_CR54","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1097\/MEG.0b013e3282f5195a","volume":"20","author":"HR Dalton","year":"2008","unstructured":"Dalton HR, Stableforth W, Thurairajah P, Hazeldine S, Remnarace R, Usama W, Farrington L, Hamad N, Sieberhagen C, Ellis V, Mitchell J, Hussaini SH, Banks M, Ijaz S, Bendall RP (2008) Autochthonous hepatitis E in Southwest England: natural history, complications and seasonal variation, and hepatitis E virus IgG seroprevalence in blood donors, the elderly and patients with chronic liver disease. Eur J Gastroenterol Hepatol 20(8):784\u2013790","journal-title":"Eur J Gastroenterol Hepatol"},{"issue":"8848","key":"221_CR55","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1016\/0140-6736(93)90599-C","volume":"341","author":"HL Zaaijer","year":"1993","unstructured":"Zaaijer HL, Kok M, Lelie PN, Timmerman RJ, Chau K, van der Pal HJ (1993) Hepatitis E in The Netherlands: imported and endemic. Lancet 341(8848):826","journal-title":"Lancet"},{"issue":"3","key":"221_CR56","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1002\/jmv.1890420321","volume":"42","author":"AR Zanetti","year":"1994","unstructured":"Zanetti AR, Dawson GJ (1994) Hepatitis type E in Italy: a seroepidemiological survey. Study group of hepatitis E. J Med Virol 42(3):318\u2013320","journal-title":"J Med Virol"},{"issue":"8924","key":"221_CR57","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1016\/S0140-6736(94)92235-7","volume":"344","author":"D Lavanchy","year":"1994","unstructured":"Lavanchy D, Morel B, Frei PC (1994) Seroprevalence of hepatitis E virus in Switzerland. Lancet 344(8924):747\u2013748","journal-title":"Lancet"},{"issue":"4","key":"221_CR58","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1046\/j.1423-0410.1998.7540267.x","volume":"75","author":"ML Mateos","year":"1998","unstructured":"Mateos ML, Camarero C, Lasa E, Teruel JL, Mir N, Baquero F (1998) Hepatitis E virus: relevance in blood donors and other risk groups. Vox Sang 75(4):267\u2013269","journal-title":"Vox Sang"},{"issue":"9","key":"221_CR59","doi-asserted-by":"publisher","first-page":"1302","DOI":"10.1086\/656598","volume":"202","author":"A Eick","year":"2010","unstructured":"Eick A, Ticehurst J, Tobler S, Nevin R, Lindler L, Hu Z, MacIntosh V, Jarman R, Gibbons R, Myint K, Gaydos J (2010) Hepatitis E seroprevalence and seroconversion among US military service members deployed to Afghanistan. J Infect Dis 202(9):1302\u20131308","journal-title":"J Infect Dis"},{"issue":"2","key":"221_CR60","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1002\/jmv.21678","volume":"82","author":"M Takahashi","year":"2010","unstructured":"Takahashi M, Tamura K, Hoshino Y, Nagashima S, Yazaki Y, Mizuo H, Iwamoto S, Okayama M, Nakamura Y, Kajii E, Okamoto H (2010) A nationwide survey of hepatitis E virus infection in the general population of Japan. J Med Virol 82(2):271\u2013281","journal-title":"J Med Virol"},{"issue":"4","key":"221_CR61","doi-asserted-by":"crossref","first-page":"384","DOI":"10.4269\/ajtmh.2002.66.384","volume":"66","author":"MR Withers","year":"2002","unstructured":"Withers MR, Correa MT, Morrow M, Stebbins ME, Seriwatana J, Webster WD, Boak MB, Vaughn DW (2002) Antibody levels to hepatitis E virus in North Carolina swine workers, non-swine workers, swine, and murids. Am J Trop Med Hyg 66(4):384\u2013388","journal-title":"Am J Trop Med Hyg"},{"issue":"7\u20138","key":"221_CR62","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1111\/j.1863-2378.2009.01254.x","volume":"57","author":"E Meader","year":"2010","unstructured":"Meader E, Thomas D, Salmon R, Sillis M (2010) Seroprevalence of hepatitis E virus in the UK farming population. Zoonoses Public Health 57(7\u20138):504\u2013509","journal-title":"Zoonoses Public Health"},{"issue":"3","key":"221_CR63","first-page":"181","volume":"19","author":"A Vulcano","year":"2007","unstructured":"Vulcano A, Angelucci M, Candelori E, Martini V, Patti AM, Mancini C, Santi AL, Calvani A, Casagni L, Lamberti A (2007) HEV prevalence in the general population and among workers at zoonotic risk in Latium Region. Ann Ig 19(3):181\u2013186","journal-title":"Ann Ig"},{"issue":"1","key":"221_CR64","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1080\/00365540500321470","volume":"38","author":"B Olsen","year":"2006","unstructured":"Olsen B, Axelsson-Olsson D, Thelin A, Weiland O (2006) Unexpected high prevalence of IgG-antibodies to hepatitis E virus in Swedish pig farmers and controls. Scand J Infect Dis 38(1):55\u201358","journal-title":"Scand J Infect Dis"},{"issue":"8","key":"221_CR65","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1017\/S0950268811000677","volume":"139","author":"BJ Wilhelm","year":"2011","unstructured":"Wilhelm BJ, Rajic A, Greig J, Waddell L, Trottier G, Houde A, Harris J, Borden LN, Price C (2011) A systematic review\/meta-analysis of primary research investigating swine, pork or pork products as a source of zoonotic hepatitis E virus. Epidemiol Infect 139(8):1127\u20131144","journal-title":"Epidemiol Infect"},{"key":"221_CR66","doi-asserted-by":"crossref","unstructured":"Reinheimer C, Allwinn R, Berger A (2011) Hepatitis E: are psychiatric patients on special risk? Med Microbiol Immunol (in press)","DOI":"10.1007\/s00430-011-0218-x"}],"container-title":["Medical Microbiology and Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00430-011-0221-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00430-011-0221-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00430-011-0221-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00430-011-0221-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T03:42:11Z","timestamp":1744170131000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00430-011-0221-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12,18]]},"references-count":66,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,5]]}},"alternative-id":["221"],"URL":"https:\/\/doi.org\/10.1007\/s00430-011-0221-2","relation":{},"ISSN":["0300-8584","1432-1831"],"issn-type":[{"value":"0300-8584","type":"print"},{"value":"1432-1831","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,12,18]]},"assertion":[{"value":"16 September 2011","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 December 2011","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}