{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T04:08:32Z","timestamp":1744258112859,"version":"3.40.4"},"reference-count":130,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2016,8,12]],"date-time":"2016-08-12T00:00:00Z","timestamp":1470960000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2016,8,12]],"date-time":"2016-08-12T00:00:00Z","timestamp":1470960000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100003042","name":"Else Kr\u00f6ner-Fresenius-Stiftung","doi-asserted-by":"publisher","award":["2013_A203"],"award-info":[{"award-number":["2013_A203"]}],"id":[{"id":"10.13039\/501100003042","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Microbiol Immunol"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1007\/s00430-016-0472-z","type":"journal-article","created":{"date-parts":[[2016,8,12]],"date-time":"2016-08-12T15:42:47Z","timestamp":1471016567000},"page":"537-547","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Prospects of a vaccine for the prevention of congenital cytomegalovirus disease"],"prefix":"10.1007","volume":"205","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8388-2288","authenticated-orcid":false,"given":"Bodo","family":"Plachter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,8,12]]},"reference":[{"key":"472_CR1","doi-asserted-by":"publisher","first-page":"2111","DOI":"10.1056\/NEJMoa1006561","volume":"364","author":"SB Boppana","year":"2011","unstructured":"Boppana SB, Ross SA, Shimamura M, Palmer AL, Ahmed A, Michaels MG, Sanchez PJ, Bernstein DI, Tolan RW Jr, Novak Z, Chowdhury N, Britt WJ, Fowler KB (2011) Saliva polymerase-chain-reaction assay for cytomegalovirus screening in newborns. New Engl J Med 364:2111\u20132118","journal-title":"New Engl J Med"},{"key":"472_CR2","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1086\/600882","volume":"49","author":"MM Mussi-Pinhata","year":"2009","unstructured":"Mussi-Pinhata MM, Yamamoto AY, Moura Brito RM, de Lima Isaac M, de Carvalhoe Oliveira PF, Boppana S, Britt WJ (2009) Birth prevalence and natural history of congenital cytomegalovirus infection in a highly seroimmune population. Clin Infect Dis 49:522\u2013528","journal-title":"Clin Infect Dis"},{"key":"472_CR3","first-page":"26","volume-title":"Cytomegaloviruses From molecular pathogenesis to intervention","author":"MJ Cannon","year":"2013","unstructured":"Cannon MJ, Grosse SD, Fowler KB (2013) The epidemiology and public health impact of congenital cytomegalovirus infection. In: Reddehase MJ (ed) Cytomegaloviruses From molecular pathogenesis to intervention. Caister Academic Press, Norfolk, pp 26\u201348"},{"key":"472_CR4","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1542\/peds.66.5.758","volume":"66","author":"RF Pass","year":"1980","unstructured":"Pass RF, Stagno S, Myers GJ, Alford CA (1980) Outcome of symptomatic congenital cytomegalovirus infection: results of long-term longitudinal follow-up. Pediatrics 66:758\u2013762","journal-title":"Pediatrics"},{"key":"472_CR5","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1097\/00006454-199202000-00007","volume":"11","author":"SB Boppana","year":"1992","unstructured":"Boppana SB, Pass RF, Britt WJ, Stagno S, Alford CA (1992) Symptomatic congenital cytomegalovirus infection: neonatal morbidity and mortality. Pediatr Infect Dis J 11:93\u201399","journal-title":"Pediatr Infect Dis J"},{"key":"472_CR6","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1016\/j.jpeds.2013.12.007","volume":"164","author":"AM Dreher","year":"2014","unstructured":"Dreher AM, Arora N, Fowler KB, Novak Z, Britt WJ, Boppana SB, Ross SA (2014) Spectrum of disease and outcome in children with symptomatic congenital cytomegalovirus infection. J Pediatr 164:855\u2013859","journal-title":"J Pediatr"},{"issue":"Suppl 4","key":"472_CR7","doi-asserted-by":"publisher","first-page":"S178","DOI":"10.1093\/cid\/cit629","volume":"57","author":"SB Boppana","year":"2013","unstructured":"Boppana SB, Ross SA, Fowler KB (2013) Congenital cytomegalovirus infection: clinical outcome. Clin Infect Dis 57(Suppl 4):S178\u2013S181","journal-title":"Clin Infect Dis"},{"key":"472_CR8","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1007\/s00430-015-0399-9","volume":"204","author":"W Britt","year":"2015","unstructured":"Britt W (2015) Controversies in the natural history of congenital human cytomegalovirus infection: the paradox of infection and disease in offspring of women with immunity prior to pregnancy. Med Microbiol Immunol 204:263\u2013271","journal-title":"Med Microbiol Immunol"},{"key":"472_CR9","first-page":"1","volume-title":"Cytomegaloviruses From molecular pathogenesis to intervention","author":"SB Boppana","year":"2013","unstructured":"Boppana SB, Britt WJ (2013) Synopsis of clinical aspects of human cytomegalovirus disease. In: Reddehase MJ (ed) Cytomegaloviruses From molecular pathogenesis to intervention. Caister Academic Press, Norfolk, pp 1\u201325"},{"key":"472_CR10","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1186\/1471-2458-5-70","volume":"5","author":"MJ Cannon","year":"2005","unstructured":"Cannon MJ, Davis KF (2005) Washing our hands of the congenital cytomegalovirus disease epidemic. BMC Public Health 5:70","journal-title":"BMC Public Health"},{"key":"472_CR11","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1086\/421999","volume":"39","author":"AM Arvin","year":"2004","unstructured":"Arvin AM, Fast P, Myers M, Plotkin S, Rabinovich R (2004) Vaccine development to prevent cytomegalovirus disease: report from the National Vaccine Advisory Committee. Clin Infect Dis 39:233\u2013239","journal-title":"Clin Infect Dis"},{"key":"472_CR12","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.vaccine.2013.09.042","volume":"32","author":"PR Krause","year":"2013","unstructured":"Krause PR, Bialek SR, Boppana SB, Griffiths PD, Laughlin CA, Ljungman P, Mocarski ES, Pass RF, Read JS, Schleiss MR, Plotkin SA (2013) Priorities for CMV vaccine development. Vaccine 32:4\u201310","journal-title":"Vaccine"},{"key":"472_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0140-6736(74)92997-3","volume":"1","author":"SD Elek","year":"1974","unstructured":"Elek SD, Stern H (1974) Development of a vaccine against mental retardation caused by cytomegalovirus infection in utero. Lancet 1:1\u20135","journal-title":"Lancet"},{"key":"472_CR14","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1128\/iai.12.3.521-527.1975","volume":"12","author":"SA Plotkin","year":"1975","unstructured":"Plotkin SA, Furukawa T, Zygraich N, Huygelen C (1975) Candidate cytomegalovirus strain for human vaccination. Infect Immun 12:521\u2013527","journal-title":"Infect Immun"},{"key":"472_CR15","first-page":"424","volume-title":"Cytomegaloviruses: From molecular pathogenesis to intervention","author":"SA Plotkin","year":"2013","unstructured":"Plotkin SA, Plachter B (2013) Cytomegalovirus Vaccine: On the Way to the Future? In: Reddehase MJ (ed) Cytomegaloviruses: From molecular pathogenesis to intervention. Caister Academic Press, Norfolk, pp 424\u2013449"},{"key":"472_CR16","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1007\/s00430-015-0388-z","volume":"204","author":"S Plotkin","year":"2015","unstructured":"Plotkin S (2015) The history of vaccination against cytomegalovirus. Med Microbiol Immunol 204:247\u2013254","journal-title":"Med Microbiol Immunol"},{"key":"472_CR17","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1586\/erv.13.46","volume":"12","author":"V Dasari","year":"2013","unstructured":"Dasari V, Smith C, Khanna R (2013) Recent advances in designing an effective vaccine to prevent cytomegalovirus-associated clinical diseases. Expert Rev Vaccines 12:661\u2013676","journal-title":"Expert Rev Vaccines"},{"key":"472_CR18","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1038\/cmi.2014.120","volume":"12","author":"AL McCormick","year":"2015","unstructured":"McCormick AL, Mocarski ES (2015) The immunological underpinnings of vaccinations to prevent cytomegalovirus disease. Cell Mol Immunol 12:170\u2013179","journal-title":"Cell Mol Immunol"},{"key":"472_CR19","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1586\/14760584.4.3.381","volume":"4","author":"MR Schleiss","year":"2005","unstructured":"Schleiss MR, Heineman TC (2005) Progress toward an elusive goal: current status of cytomegalovirus vaccines. Expert Rev Vaccines 4:381\u2013406","journal-title":"Expert Rev Vaccines"},{"key":"472_CR20","doi-asserted-by":"publisher","first-page":"2525","DOI":"10.1016\/j.vaccine.2014.03.057","volume":"32","author":"TM Fu","year":"2014","unstructured":"Fu TM, An Z, Wang D (2014) Progress on pursuit of human cytomegalovirus vaccines for prevention of congenital infection and disease. Vaccine 32:2525\u20132533","journal-title":"Vaccine"},{"key":"472_CR21","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/rmv.535","volume":"17","author":"A Kenneson","year":"2007","unstructured":"Kenneson A, Cannon MJ (2007) Review and meta-analysis of the epidemiology of congenital cytomegalovirus (CMV) infection. Rev Med Virol 17:253\u2013276","journal-title":"Rev Med Virol"},{"key":"472_CR22","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1016\/j.jcv.2011.07.005","volume":"52","author":"G Enders","year":"2011","unstructured":"Enders G, Daiminger A, Bader U, Exler S, Enders M (2011) Intrauterine transmission and clinical outcome of 248 pregnancies with primary cytomegalovirus infection in relation to gestational age. J Clin Virol 52:244\u2013246","journal-title":"J Clin Virol"},{"key":"472_CR23","doi-asserted-by":"publisher","first-page":"1904","DOI":"10.1001\/jama.1986.03380140074025","volume":"256","author":"S Stagno","year":"1986","unstructured":"Stagno S, Pass RF, Cloud G, Britt WJ, Henderson RE, Walton PD, Veren DA, Page F, Alford CA (1986) Primary cytomegalovirus infection in pregnancy. Incidence, transmission to fetus, and clinical outcome. JAMA 256:1904\u20131908","journal-title":"JAMA"},{"key":"472_CR24","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.1093\/cid\/cit018","volume":"56","author":"CL Townsend","year":"2013","unstructured":"Townsend CL, Forsgren M, Ahlfors K, Ivarsson SA, Tookey PA, Peckham CS (2013) Long-term outcomes of congenital cytomegalovirus infection in Sweden and the United Kingdom. Clin Infect Dis 56:1232\u20131239","journal-title":"Clin Infect Dis"},{"key":"472_CR25","doi-asserted-by":"publisher","first-page":"1227","DOI":"10.1542\/peds.107.5.1227","volume":"107","author":"K Ahlfors","year":"2001","unstructured":"Ahlfors K, Ivarsson SA, Harris S (2001) Secondary maternal cytomegalovirus infection\u2014a significant cause of congenital disease. Pediatrics 107:1227\u20131228","journal-title":"Pediatrics"},{"key":"472_CR26","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/j.jpeds.2005.09.003","volume":"148","author":"SA Ross","year":"2006","unstructured":"Ross SA, Fowler KB, Ashrith G, Stagno S, Britt WJ, Pass RF, Boppana SB (2006) Hearing loss in children with congenital cytomegalovirus infection born to mothers with preexisting immunity. J Pediatr 148:332\u2013336","journal-title":"J Pediatr"},{"key":"472_CR27","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/j.ajog.2009.11.018","volume":"202","author":"AY Yamamoto","year":"2010","unstructured":"Yamamoto AY, Mussi-Pinhata MM, Boppana SB, Novak Z, Wagatsuma VM, Oliveira PF, Duarte G, Britt WJ (2010) Human cytomegalovirus reinfection is associated with intrauterine transmission in a highly cytomegalovirus-immune maternal population. Am J Obstet Gynecol 202:297\u2013298","journal-title":"Am J Obstet Gynecol"},{"key":"472_CR28","doi-asserted-by":"publisher","first-page":"129","DOI":"10.3109\/00365548409087131","volume":"16","author":"K Ahlfors","year":"1984","unstructured":"Ahlfors K, Ivarsson SA, Harris S, Svanberg L, Holmqvist R, Lernmark B, Theander G (1984) Congenital cytomegalovirus infection and disease in Sweden and the relative importance of primary and secondary maternal infections. Preliminary findings from a prospective study. Scand J Infect Dis 16:129\u2013137","journal-title":"Scand J Infect Dis"},{"key":"472_CR29","doi-asserted-by":"publisher","first-page":"1366","DOI":"10.1056\/NEJM200105033441804","volume":"344","author":"SB Boppana","year":"2001","unstructured":"Boppana SB, Rivera LB, Fowler KB, Mach M, Britt WJ (2001) Intrauterine transmission of cytomegalovirus to infants of women with preconceptional immunity. New Engl J Med 344:1366\u20131371","journal-title":"New Engl J Med"},{"key":"472_CR30","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1097\/INF.0b013e3181723d55","volume":"27","author":"L Dar","year":"2008","unstructured":"Dar L, Pati SK, Patro AR, Deorari AK, Rai S, Kant S, Broor S, Fowler KB, Britt WJ, Boppana SB (2008) Congenital cytomegalovirus infection in a highly seropositive semi-urban population in India. Pediatr Infect Dis J 27:841\u2013843","journal-title":"Pediatr Infect Dis J"},{"key":"472_CR31","doi-asserted-by":"publisher","first-page":"e492","DOI":"10.1371\/journal.pone.0000492","volume":"2","author":"MA van der Sande","year":"2007","unstructured":"van der Sande MA, Kaye S, Miles DJ, Waight P, Jeffries DJ, Ojuola OO, Palmero M, Pinder M, Ismaili J, Flanagan KL, Aveika AA, Zaman A, Rowland-Jones S, McConkey SJ, Whittle HC, Marchant A (2007) Risk factors for and clinical outcome of congenital cytomegalovirus infection in a peri-urban West-African birth cohort. PLoS One 2:e492","journal-title":"PLoS One"},{"key":"472_CR32","doi-asserted-by":"publisher","first-page":"e11","DOI":"10.1093\/cid\/ciq085","volume":"52","author":"C Wang","year":"2011","unstructured":"Wang C, Zhang X, Bialek S, Cannon MJ (2011) Attribution of congenital cytomegalovirus infection to primary versus non-primary maternal infection. Clin Infect Dis 52:e11\u2013e13","journal-title":"Clin Infect Dis"},{"key":"472_CR33","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1002\/rmv.659","volume":"20","author":"TB Hyde","year":"2010","unstructured":"Hyde TB, Schmid DS, Cannon MJ (2010) Cytomegalovirus seroconversion rates and risk factors: implications for congenital CMV. Rev Med Virol 20:311\u2013326","journal-title":"Rev Med Virol"},{"key":"472_CR34","doi-asserted-by":"publisher","first-page":"3472","DOI":"10.1182\/blood-2007-06-095414","volume":"110","author":"K Klenovsek","year":"2007","unstructured":"Klenovsek K, Weisel F, Schneider A, Appelt U, Jonjic S, Messerle M, Bradel-Tretheway B, Winkler TH, Mach M (2007) Protection from CMV infection in immunodeficient hosts by adoptive transfer of memory B cells. Blood 110:3472\u20133479","journal-title":"Blood"},{"key":"472_CR35","doi-asserted-by":"publisher","first-page":"12172","DOI":"10.1128\/JVI.01214-08","volume":"82","author":"D Cekinovic","year":"2008","unstructured":"Cekinovic D, Golemac M, Pugel EP, Tomac J, Cicin-Sain L, Slavuljica I, Bradford R, Misch S, Winkler TH, Mach M, Britt WJ, Jonjic S (2008) Passive immunization reduces murine cytomegalovirus-induced brain pathology in newborn mice. J Virol 82:12172\u201312180","journal-title":"J Virol"},{"key":"472_CR36","doi-asserted-by":"publisher","first-page":"1298","DOI":"10.2353\/ajpath.2010.091210","volume":"177","author":"E Maidji","year":"2010","unstructured":"Maidji E, Nigro G, Tabata T, McDonagh S, Nozawa N, Shiboski S, Muci S, Anceschi MM, Aziz N, Adler SP, Pereira L (2010) Antibody treatment promotes compensation for human cytomegalovirus-induced pathogenesis and a hypoxia-like condition in placentas with congenital infection. Am J Pathol 177:1298\u20131310","journal-title":"Am J Pathol"},{"key":"472_CR37","doi-asserted-by":"publisher","first-page":"1558","DOI":"10.1128\/AAC.04295-14","volume":"59","author":"LM Kauvar","year":"2015","unstructured":"Kauvar LM, Liu K, Park M, DeChene N, Stephenson R, Tenorio E, Ellsworth SL, Tabata T, Petitt M, Tsuge M, Fang-Hoover J, Adler SP, Cui X, McVoy MA, Pereira L (2015) A high-affinity native human antibody neutralizes human cytomegalovirus infection of diverse cell types. Antimicrob Agents Chemother 59:1558\u20131568","journal-title":"Antimicrob Agents Chemother"},{"key":"472_CR38","doi-asserted-by":"publisher","first-page":"1350","DOI":"10.1056\/NEJMoa043337","volume":"353","author":"G Nigro","year":"2005","unstructured":"Nigro G, Adler SP, La TR, Best AM (2005) Passive immunization during pregnancy for congenital cytomegalovirus infection. New Engl J Med 353:1350\u20131362","journal-title":"New Engl J Med"},{"key":"472_CR39","doi-asserted-by":"publisher","first-page":"1316","DOI":"10.1056\/NEJMoa1310214","volume":"370","author":"MG Revello","year":"2014","unstructured":"Revello MG, Lazzarotto T, Guerra B, Spinillo A, Ferrazzi E, Kustermann A, Guaschino S, Vergani P, Todros T, Frusca T, Arossa A, Furione M, Rognoni V, Rizzo N, Gabrielli L, Klersy C, Gerna G (2014) A randomized trial of hyperimmune globulin to prevent congenital cytomegalovirus. New Engl J Med 370:1316\u20131326","journal-title":"New Engl J Med"},{"key":"472_CR40","doi-asserted-by":"publisher","first-page":"4961","DOI":"10.1128\/AAC.00382-16","volume":"60","author":"HD Patel","year":"2016","unstructured":"Patel HD, Nikitin P, Gesner T, Lin JJ, Barkan DT, Ciferri C, Carfi A, Akbarnejad YT, Skewes-Cox P, Wiedmann B, Jarousse N, Zhong W, Feire A, Hebner CM (2016) In vitro characterization of human cytomegalovirus-targeting therapeutic monoclonal antibodies LJP538 and LJP539. Antimicrob Agents Chemother 60:4961\u20134971","journal-title":"Antimicrob Agents Chemother"},{"key":"472_CR41","doi-asserted-by":"publisher","first-page":"2881","DOI":"10.1128\/AAC.02698-15","volume":"60","author":"K Dole","year":"2016","unstructured":"Dole K, Segal FP, Feire A, Magnusson B, Rondon JC, Vemula J, Yu J, Pang Y, Pertel P (2016) A first-in-human study to assess the safety and pharmacokinetics of monoclonal antibodies against human cytomegalovirus in healthy volunteers. Antimicrob Agents Chemother 60:2881\u20132887","journal-title":"Antimicrob Agents Chemother"},{"key":"472_CR42","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1007\/s00430-013-0321-2","volume":"203","author":"K Frenzel","year":"2014","unstructured":"Frenzel K, Lehmann J, Kr\u00fcger DH, Martin-Parras L, Uharek L, Hofmann J (2014) Combination of immunoglobulins and natural killer cells in the context of CMV and EBV infection. Med Microbiol Immunol 203:115\u2013123","journal-title":"Med Microbiol Immunol"},{"key":"472_CR43","first-page":"215","volume-title":"Cytomegaloviruses From molecular pathogenesis to intervention","author":"M Mach","year":"2013","unstructured":"Mach M, Wiegers AK, Spindler N, Winkler TH (2013) Protective humoral immunity. In: Reddehase MJ (ed) Cytomegaloviruses From molecular pathogenesis to intervention. Caister Academic Press, Norfolk, pp 215\u2013231"},{"key":"472_CR44","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1128\/jvi.64.3.1079-1085.1990","volume":"64","author":"WJ Britt","year":"1990","unstructured":"Britt WJ, Vugler L, Butfiloski EJ, Stephens EB (1990) Cell surface expression of human cytomegalovirus (HCMV) gp55-116 (gB): use of HCMV-recombinant vaccinia virus-infected cells in analysis of the human neutralizing antibody response. J Virol 64:1079\u20131085","journal-title":"J Virol"},{"key":"472_CR45","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1093\/infdis\/165.2.381","volume":"165","author":"GS Marshall","year":"1992","unstructured":"Marshall GS, Rabalais GP, Stout GG, Waldeyer SL (1992) Antibodies to recombinant-derived glycoprotein B after natural human cytomegalovirus infection correlate with neutralizing activity. J Infect Dis 165:381\u2013384","journal-title":"J Infect Dis"},{"key":"472_CR46","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1093\/infdis\/175.3.533","volume":"175","author":"K Schoppel","year":"1997","unstructured":"Schoppel K, Kropff B, Schmidt C, Vornhagen R, Mach M (1997) The humoral immune response against human cytomegalovirus is characterized by a delayed synthesis of glycoprotein-specific antibodies. J Infect Dis 175:533\u2013544","journal-title":"J Infect Dis"},{"key":"472_CR47","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1002\/jmv.2096","volume":"65","author":"M Rothe","year":"2001","unstructured":"Rothe M, Pepperl-Klindworth S, Lang D, Vornhagen R, Hinderer W, Weise K, Sonneborn HH, Plachter B (2001) An antigen fragment encompassing the AD2 domains of glycoprotein B from two different strains is sufficient for differentiation of primary vs. recurrent human cytomegalovirus infection by ELISA. J Med Virol 65:719\u2013729","journal-title":"J Med Virol"},{"key":"472_CR48","doi-asserted-by":"publisher","first-page":"1642","DOI":"10.1093\/infdis\/jiv769","volume":"213","author":"N Dauby","year":"2016","unstructured":"Dauby N, Sartori D, Kummert C, Lecomte S, Haelterman E, Delforge ML, Donner C, Mach M, Marchant A (2016) Limited effector memory B-Cell response to envelope glycoprotein B during primary human cytomegalovirus infection. J Infect Dis 213:1642\u20131650","journal-title":"J Infect Dis"},{"key":"472_CR49","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1128\/MMBR.00018-16","volume":"80","author":"TJ Gardner","year":"2016","unstructured":"Gardner TJ, Tortorella D (2016) Virion glycoprotein-mediated immune evasion by human cytomegalovirus: a sticky virus makes a slick getaway. Microbiol Mol Biol Rev 80:663\u2013677","journal-title":"Microbiol Mol Biol Rev"},{"key":"472_CR50","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.1016\/S0140-6736(11)60136-0","volume":"377","author":"PD Griffiths","year":"2011","unstructured":"Griffiths PD, Stanton A, McCarrell E, Smith C, Osman M, Harber M, Davenport A, Jones G, Wheeler DC, O\u2019Beirne J, Thorburn D, Patch D, Atkinson CE, Pichon S, Sweny P, Lanzman M, Woodford E, Rothwell E, Old N, Kinyanjui R, Haque T, Atabani S, Luck S, Prideaux S, Milne RS, Emery VC, Burroughs AK (2011) Cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in transplant recipients: a phase 2 randomised placebo-controlled trial. Lancet 377:1256\u20131263","journal-title":"Lancet"},{"key":"472_CR51","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.1056\/NEJMoa0804749","volume":"360","author":"RF Pass","year":"2009","unstructured":"Pass RF, Zhang C, Evans A, Simpson T, Andrews W, Huang ML, Corey L, Hill J, Davis E, Flanigan C, Cloud G (2009) Vaccine prevention of maternal cytomegalovirus infection. New Engl J Med 360:1191\u20131199","journal-title":"New Engl J Med"},{"key":"472_CR52","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.vaccine.2015.11.056","volume":"34","author":"DI Bernstein","year":"2016","unstructured":"Bernstein DI, Munoz FM, Callahan ST, Rupp R, Wootton SH, Edwards KM, Turley CB, Stanberry LR, Patel SM, Mcneal MM, Pichon S, Amegashie C, Bellamy AR (2016) Safety and efficacy of a cytomegalovirus glycoprotein B (gB) vaccine in adolescent girls: a randomized clinical trial. Vaccine 34:313\u2013319","journal-title":"Vaccine"},{"key":"472_CR53","doi-asserted-by":"publisher","first-page":"e1002172","DOI":"10.1371\/journal.ppat.1002172","volume":"7","author":"S P\u00f6tzsch","year":"2011","unstructured":"P\u00f6tzsch S, Spindler N, Wiegers AK, Fisch T, Rucker P, Sticht H, Grieb N, Baroti T, Weisel F, Stamminger T, Martin-Parras L, Mach M, Winkler TH (2011) B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies. PLoS Pathog 7:e1002172","journal-title":"PLoS Pathog"},{"key":"472_CR54","doi-asserted-by":"publisher","first-page":"e1004377","DOI":"10.1371\/journal.ppat.1004377","volume":"10","author":"N Spindler","year":"2014","unstructured":"Spindler N, Diestel U, Stump JD, Wiegers AK, Winkler TH, Sticht H, Mach M, Muller YA (2014) Structural basis for the recognition of human cytomegalovirus glycoprotein B by a neutralizing human antibody. PLoS Pathog 10:e1004377","journal-title":"PLoS Pathog"},{"key":"472_CR55","doi-asserted-by":"publisher","first-page":"5760","DOI":"10.1016\/j.vaccine.2008.07.092","volume":"26","author":"X Cui","year":"2008","unstructured":"Cui X, Meza BP, Adler SP, McVoy MA (2008) Cytomegalovirus vaccines fail to induce epithelial entry neutralizing antibodies comparable to natural infection. Vaccine 26:5760\u20135766","journal-title":"Vaccine"},{"key":"472_CR56","doi-asserted-by":"publisher","first-page":"10330","DOI":"10.1128\/JVI.79.16.10330-10338.2005","volume":"79","author":"D Wang","year":"2005","unstructured":"Wang D, Shenk T (2005) Human cytomegalovirus UL131 open reading frame is required for epithelial cell tropism. J Virol 79:10330\u201310338","journal-title":"J Virol"},{"key":"472_CR57","doi-asserted-by":"publisher","first-page":"18153","DOI":"10.1073\/pnas.0509201102","volume":"102","author":"D Wang","year":"2005","unstructured":"Wang D, Shenk T (2005) Human cytomegalovirus virion protein complex required for epithelial and endothelial cell tropism. Proc Natl Acad Sci USA 102:18153\u201318158","journal-title":"Proc Natl Acad Sci USA"},{"key":"472_CR58","doi-asserted-by":"publisher","first-page":"10023","DOI":"10.1128\/JVI.78.18.10023-10033.2004","volume":"78","author":"G Hahn","year":"2004","unstructured":"Hahn G, Revello MG, Patrone M, Percivalle E, Campanini G, Sarasini A, Wagner M, Gallina A, Milanesi G, Koszinowski U, Baldanti F, Gerna G (2004) Human cytomegalovirus UL131-128 genes are indispensable for virus growth in endothelial cells and virus transfer to leukocytes. J Virol 78:10023\u201310033","journal-title":"J Virol"},{"key":"472_CR59","first-page":"297","volume-title":"Cytomegaloviruses From molecular pathogenesis to intervention","author":"B Adler","year":"2013","unstructured":"Adler B, Sinzger C (2013) Cytomegalovirus Interstrain Variance in Cell Type Tropism. In: Reddehase MJ (ed) Cytomegaloviruses From molecular pathogenesis to intervention. Caister Academic Press, Norfolk, pp 297\u2013329"},{"key":"472_CR60","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1097\/00006454-199803000-00006","volume":"17","author":"SP Adler","year":"1998","unstructured":"Adler SP, Hempfling SH, Starr SE, Plotkin SA, Riddell S (1998) Safety and immunogenicity of the Towne strain cytomegalovirus vaccine. Pediatr Infect Dis J 17:200\u2013206","journal-title":"Pediatr Infect Dis J"},{"key":"472_CR61","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1093\/infdis\/174.2.387","volume":"174","author":"JB Wang","year":"1996","unstructured":"Wang JB, Adler SP, Hempfling S, Burke RL, Duliege AM, Starr SE, Plotkin SA (1996) Mucosal antibodies to human cytomegalovirus glycoprotein B occur following both natural infection and immunization with human cytomegalovirus vaccines. J Infect Dis 174:387\u2013392","journal-title":"J Infect Dis"},{"key":"472_CR62","doi-asserted-by":"publisher","first-page":"7444","DOI":"10.1128\/JVI.00467-12","volume":"86","author":"AE Fouts","year":"2012","unstructured":"Fouts AE, Chan P, Stephan JP, Vandlen R, Feierbach B (2012) Antibodies against the gH\/gL\/UL128\/UL130\/UL131 complex comprise the majority of the anti-cytomegalovirus (anti-CMV) neutralizing antibody response in CMV hyperimmune globulin. J Virol 86:7444\u20137447","journal-title":"J Virol"},{"key":"472_CR63","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1128\/JVI.01809-09","volume":"84","author":"A Macagno","year":"2010","unstructured":"Macagno A, Bernasconi NL, Vanzetta F, Dander E, Sarasini A, Revello MG, Gerna G, Sallusto F, Lanzavecchia A (2010) Isolation of human monoclonal antibodies that potently neutralize human cytomegalovirus infection by targeting different epitopes on the gH\/gL\/UL128-131A complex. J Virol 84:1005\u20131013","journal-title":"J Virol"},{"key":"472_CR64","doi-asserted-by":"publisher","first-page":"e59863","DOI":"10.1371\/journal.pone.0059863","volume":"8","author":"D Lilleri","year":"2013","unstructured":"Lilleri D, Kabanova A, Revello MG, Percivalle E, Sarasini A, Genini E, Sallusto F, Lanzavecchia A, Corti D, Gerna G (2013) Fetal human cytomegalovirus transmission correlates with delayed maternal antibodies to gH\/gL\/pUL128-130-131 complex during primary infection. PLoS One 8:e59863","journal-title":"PLoS One"},{"key":"472_CR65","doi-asserted-by":"publisher","first-page":"11884","DOI":"10.1128\/JVI.01701-15","volume":"89","author":"F Chiuppesi","year":"2015","unstructured":"Chiuppesi F, Wussow F, Johnson E, Bian C, Zhuo M, Rajakumar A, Barry PA, Britt WJ, Chakraborty R, Diamond DJ (2015) Vaccine-derived neutralizing antibodies to the human cytomegalovirus gH\/gL pentamer potently block primary cytotrophoblast infection. J Virol 89:11884\u201311898","journal-title":"J Virol"},{"key":"472_CR66","doi-asserted-by":"publisher","first-page":"7469","DOI":"10.1016\/j.vaccine.2012.10.053","volume":"30","author":"TM Fu","year":"2012","unstructured":"Fu TM, Wang D, Freed DC, Tang A, Li F, He X, Cole S, Dubey S, Finnefrockter AC, Ter MJ, Shiver JW, Casimiro DR (2012) Restoration of viral epithelial tropism improves immunogenicity in rabbits and rhesus macaques for a whole virion vaccine of human cytomegalovirus. Vaccine 30:7469\u20137474","journal-title":"Vaccine"},{"key":"472_CR67","doi-asserted-by":"publisher","first-page":"3796","DOI":"10.1016\/j.vaccine.2014.05.004","volume":"32","author":"Y Wen","year":"2014","unstructured":"Wen Y, Monroe J, Linton C, Archer J, Beard CW, Barnett SW, Palladino G, Mason PW, Carfi A, Lilja AE (2014) Human cytomegalovirus gH\/gL\/UL128\/UL130\/UL131A complex elicits potently neutralizing antibodies in mice. Vaccine 32:3796\u20133804","journal-title":"Vaccine"},{"key":"472_CR68","doi-asserted-by":"publisher","first-page":"e1004524","DOI":"10.1371\/journal.ppat.1004524","volume":"10","author":"F Wussow","year":"2014","unstructured":"Wussow F, Chiuppesi F, Martinez J, Campo J, Johnson E, Flechsig C, Newell M, Tran E, Ortiz J, La RC, Herrmann A, Longmate J, Chakraborty R, Barry PA, Diamond DJ (2014) Human cytomegalovirus vaccine based on the envelope gH\/gL pentamer complex. PLoS Pathog 10:e1004524","journal-title":"PLoS Pathog"},{"key":"472_CR69","doi-asserted-by":"publisher","first-page":"17965","DOI":"10.1073\/pnas.1415310111","volume":"111","author":"A Kabanova","year":"2014","unstructured":"Kabanova A, Perez L, Lilleri D, Marcandalli J, Agatic G, Becattini S, Preite S, Fuschillo D, Percivalle E, Sallusto F, Gerna G, Corti D, Lanzavecchia A (2014) Antibody-driven design of a human cytomegalovirus gHgLpUL128L subunit vaccine that selectively elicits potent neutralizing antibodies. Proc Natl Acad Sci USA 111:17965\u201317970","journal-title":"Proc Natl Acad Sci USA"},{"key":"472_CR70","doi-asserted-by":"publisher","first-page":"2505","DOI":"10.1002\/bit.25670","volume":"112","author":"I Hofmann","year":"2015","unstructured":"Hofmann I, Wen Y, Ciferri C, Schulze A, Fuhner V, Leong M, Gerber A, Gerrein R, Nandi A, Lilja AE, Carfi A, Laux H (2015) Expression of the human cytomegalovirus pentamer complex for vaccine use in a CHO system. Biotechnol Bioeng 112:2505\u20132515","journal-title":"Biotechnol Bioeng"},{"key":"472_CR71","doi-asserted-by":"publisher","first-page":"7328","DOI":"10.1016\/j.vaccine.2015.10.078","volume":"33","author":"MA McVoy","year":"2015","unstructured":"McVoy MA, Lee R, Saccoccio FM, Hartikka J, Smith LR, Mahajan R, Wang JB, Cui X, Adler SP (2015) A cytomegalovirus DNA vaccine induces antibodies that block viral entry into fibroblasts and epithelial cells. Vaccine 33:7328\u20137336","journal-title":"Vaccine"},{"key":"472_CR72","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1159\/000150510","volume":"39","author":"WJ Britt","year":"1996","unstructured":"Britt WJ, Mach M (1996) Human Cytomegalovirus Glycoproteins. Intervirology 39:401\u2013412","journal-title":"Intervirology"},{"key":"472_CR73","doi-asserted-by":"publisher","first-page":"11881","DOI":"10.1128\/JVI.74.24.11881-11892.2000","volume":"74","author":"M Mach","year":"2000","unstructured":"Mach M, Kropff B, Dal Monte P, Britt W (2000) Complex formation by human cytomegalovirus glycoproteins M (gpUL100) and N (gpUL73). J Virol 74:11881\u201311892","journal-title":"J Virol"},{"key":"472_CR74","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1007\/s00430-015-0405-2","volume":"204","author":"J Podlech","year":"2015","unstructured":"Podlech J, Reddehase MJ, Adler B, Lemmermann NA (2015) Principles for studying in vivo attenuation of virus mutants: defining the role of the cytomegalovirus gH\/gL\/gO complex as a paradigm. Med Microbiol Immunol 204:295\u2013305","journal-title":"Med Microbiol Immunol"},{"key":"472_CR75","doi-asserted-by":"publisher","first-page":"e1004640","DOI":"10.1371\/journal.ppat.1004640","volume":"11","author":"NA Lemmermann","year":"2015","unstructured":"Lemmermann NA, Krmpotic A, Podlech J, Brizic I, Prager A, Adler H, Karbach A, Wu Y, Jonjic S, Reddehase MJ, Adler B (2015) Non-redundant and redundant roles of cytomegalovirus gH\/gL complexes in host organ entry and intra-tissue spread. PLoS Pathog 11:e1004640","journal-title":"PLoS Pathog"},{"key":"472_CR76","doi-asserted-by":"publisher","unstructured":"Corrales-Aguilar, E, Trilling, M, Reinhard, H, Falcone, V, Zimmermann, A, Adams, O, Santibanez, S, Hengel, H (2016) Highly individual patterns of virus-immune IgG effector responses in humans. Med Microbiol Immunol. doi:10.1007\/s00430-016-0457-y","DOI":"10.1007\/s00430-016-0457-y"},{"key":"472_CR77","doi-asserted-by":"publisher","first-page":"11323","DOI":"10.1128\/JVI.01925-13","volume":"87","author":"MK Eberhardt","year":"2013","unstructured":"Eberhardt MK, Deshpande A, Chang WL, Barthold SW, Walter MR, Barry PA (2013) Vaccination against a virus-encoded cytokine significantly restricts viral challenge. J Virol 87:11323\u201311331","journal-title":"J Virol"},{"key":"472_CR78","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1007\/s00430-015-0406-1","volume":"204","author":"PA Barry","year":"2015","unstructured":"Barry PA (2015) Exploiting viral natural history for vaccine development. Med Microbiol Immunol 204:255\u2013262","journal-title":"Med Microbiol Immunol"},{"key":"472_CR79","doi-asserted-by":"crossref","first-page":"3102","DOI":"10.1128\/jvi.61.10.3102-3108.1987","volume":"61","author":"MJ Reddehase","year":"1987","unstructured":"Reddehase MJ, Mutter W, M\u00fcnch K, B\u00fchring HJ, Koszinowski UH (1987) CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity. J Virol 61:3102\u20133108","journal-title":"J Virol"},{"key":"472_CR80","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1126\/science.1352912","volume":"257","author":"SR Riddell","year":"1992","unstructured":"Riddell SR, Watanabe KS, Goodrich JM, Li CR, Agha ME, Greenberg PD (1992) Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones. Science 257:238\u2013241","journal-title":"Science"},{"key":"472_CR81","doi-asserted-by":"publisher","first-page":"1038","DOI":"10.1056\/NEJM199510193331603","volume":"333","author":"EA Walter","year":"1995","unstructured":"Walter EA, Greenberg PD, Gilbert MJ, Finch RJ, Watanabe KS, Thomas ED, Riddell SR (1995) Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor. New Engl J Med 333:1038\u20131044","journal-title":"New Engl J Med"},{"key":"472_CR82","doi-asserted-by":"publisher","first-page":"10436","DOI":"10.1128\/JVI.01248-06","volume":"80","author":"CO Simon","year":"2006","unstructured":"Simon CO, Holtappels R, Tervo HM, B\u00f6hm V, D\u00e4ubner T, Oehrlein-Karpi SA, K\u00fchnapfel B, Renzaho A, Strand D, Podlech J, Reddehase MJ, Grzimek NKA (2006) CD8 T cells control cytomegalovirus latency by epitope-specific sensing of transcriptional reactivation. J Virol 80:10436\u201310456","journal-title":"J Virol"},{"key":"472_CR83","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1007\/s00430-012-0258-x","volume":"201","author":"S Ebert","year":"2012","unstructured":"Ebert S, Podlech J, Gillert-Marien D, Gergely KM, Buttner JK, Fink A, Freitag K, Thomas D, Reddehase MJ, Holtappels R (2012) Parameters determining the efficacy of adoptive CD8 T-cell therapy of cytomegalovirus infection. Med Microbiol Immunol 201:527\u2013539","journal-title":"Med Microbiol Immunol"},{"key":"472_CR84","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1007\/s00430-012-0268-8","volume":"201","author":"S Ebert","year":"2012","unstructured":"Ebert S, Lemmermann NA, Thomas D, Renzaho A, Reddehase MJ, Holtappels R (2012) Immune control in the absence of immunodominant epitopes: implications for immunotherapy of cytomegalovirus infection with antiviral CD8 T cells. Med Microbiol Immunol 201:541\u2013550","journal-title":"Med Microbiol Immunol"},{"key":"472_CR85","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2016.00294","author":"MJ Reddehase","year":"2016","unstructured":"Reddehase MJ (2016) Mutual interference between cytomegalovirus and reconstitution of protective immunity after hematopoietic cell transplantation. Front Immunol. doi:10.3389\/fimmu.2016.00294","journal-title":"Front Immunol"},{"key":"472_CR86","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1182\/blood.V78.5.1373.1373","volume":"78","author":"P Reusser","year":"1991","unstructured":"Reusser P, Riddell SR, Meyers JD, Greenberg PD (1991) Cytotoxic T-lymphocyte response to cytomegalovirus after human allogeneic bone marrow transplantation: pattern of recovery and correlation with cytomegalovirus infection and disease. Blood 78:1373\u20131380","journal-title":"Blood"},{"key":"472_CR87","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1007\/s00430-015-0415-0","volume":"204","author":"JG Sissons","year":"2015","unstructured":"Sissons JG, Wills MR (2015) How understanding immunology contributes to managing CMV disease in immunosuppressed patients: now and in future. Med Microbiol Immunol 204:307\u2013316","journal-title":"Med Microbiol Immunol"},{"key":"472_CR88","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1586\/erv.09.58","volume":"8","author":"W Herr","year":"2009","unstructured":"Herr W, Plachter B (2009) Cytomegalovirus and varicella-zoster virus vaccines in hematopoietic stem cell transplantation. Expert Rev Vaccines 8:999\u20131021","journal-title":"Expert Rev Vaccines"},{"key":"472_CR89","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1586\/eci.12.25","volume":"8","author":"RR Watkins","year":"2012","unstructured":"Watkins RR, Lemonovich TL, Razonable RR (2012) Immune response to CMV in solid organ transplant recipients: current concepts and future directions. Expert Rev Clin Immunol 8:383\u2013393","journal-title":"Expert Rev Clin Immunol"},{"key":"472_CR90","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1002\/jmv.1890410205","volume":"41","author":"S Fernando","year":"1993","unstructured":"Fernando S, Pearce JM, Booth JC (1993) Lymphocyte responses and virus excretion as risk factors for intrauterine infection with cytomegalovirus. J Med Virol 41:108\u2013113","journal-title":"J Med Virol"},{"key":"472_CR91","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1136\/bmj.292.6522.718","volume":"292","author":"H Stern","year":"1986","unstructured":"Stern H, Hannington G, Booth J, Moncrieff D (1986) An early marker of fetal infection after primary cytomegalovirus infection in pregnancy. Br Med J Clin Res 292:718\u2013720","journal-title":"Br Med J Clin Res"},{"key":"472_CR92","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1086\/498872","volume":"193","author":"MG Revello","year":"2006","unstructured":"Revello MG, Lilleri D, Zavattoni M, Furione M, Genini E, Comolli G, Gerna G (2006) Lymphoproliferative response in primary human cytomegalovirus (HCMV) infection is delayed in HCMV transmitter mothers. J Infect Dis 193:269\u2013276","journal-title":"J Infect Dis"},{"key":"472_CR93","doi-asserted-by":"publisher","first-page":"1062","DOI":"10.1086\/512245","volume":"195","author":"D Lilleri","year":"2007","unstructured":"Lilleri D, Fornara C, Furione M, Zavattoni M, Revello MG, Gerna G (2007) Development of human cytomegalovirus-specific T cell immunity during primary infection of pregnant women and its correlation with virus transmission to the fetus. J Infect Dis 195:1062\u20131070","journal-title":"J Infect Dis"},{"key":"472_CR94","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.1007\/s10875-011-9577-8","volume":"31","author":"C Fornara","year":"2011","unstructured":"Fornara C, Lilleri D, Revello MG, Furione M, Zavattoni M, Lenta E, Gerna G (2011) Kinetics of effector functions and phenotype of virus-specific and gammadelta T lymphocytes in primary human cytomegalovirus infection during pregnancy. J Clin Immunol 31:1054\u20131064","journal-title":"J Clin Immunol"},{"key":"472_CR95","doi-asserted-by":"publisher","first-page":"1238","DOI":"10.1002\/jmv.24449","volume":"88","author":"C Fornara","year":"2016","unstructured":"Fornara C, Furione M, Arossa A, Gerna G, Lilleri D (2016) Comparative magnitude and kinetics of human cytomegalovirus-specific CD4(+) and CD8(+) T-cell responses in pregnant women with primary versus remote infection and in transmitting versus non-transmitting mothers: its utility for dating primary infection in pregnancy. J Med Virol 88:1238\u20131246","journal-title":"J Med Virol"},{"key":"472_CR96","doi-asserted-by":"publisher","first-page":"2665","DOI":"10.4049\/jimmunol.1101165","volume":"189","author":"P Antoine","year":"2012","unstructured":"Antoine P, Olislagers V, Huygens A, Lecomte S, Liesnard C, Donner C, Marchant A (2012) Functional exhaustion of CD4+ T lymphocytes during primary cytomegalovirus infection. J Immunol 189:2665\u20132672","journal-title":"J Immunol"},{"key":"472_CR97","doi-asserted-by":"publisher","first-page":"5134","DOI":"10.1128\/JVI.03674-14","volume":"89","author":"T Tabata","year":"2015","unstructured":"Tabata T, Petitt M, Zydek M, Fang-Hoover J, Larocque N, Tsuge M, Gormley M, Kauvar LM, Pereira L (2015) Human cytomegalovirus infection interferes with the maintenance and differentiation of trophoblast progenitor cells of the human placenta. J Virol 89:5134\u20135147","journal-title":"J Virol"},{"key":"472_CR98","doi-asserted-by":"publisher","first-page":"13645","DOI":"10.1073\/pnas.1511526112","volume":"112","author":"KM Bialas","year":"2015","unstructured":"Bialas KM, Tanaka T, Tran D, Varner V, Cisneros DLR, Chiuppesi F, Wussow F, Kattenhorn L, Macri S, Kunz EL, Estroff JA, Kirchherr J, Yue Y, Fan Q, Lauck M, O\u2019Connor DH, Hall AH, Xavier A, Diamond DJ, Barry PA, Kaur A, Permar SR (2015) Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission. Proc Natl Acad Sci USA 112:13645\u201313650","journal-title":"Proc Natl Acad Sci USA"},{"key":"472_CR99","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.tim.2016.01.007","volume":"24","author":"MR Schleiss","year":"2016","unstructured":"Schleiss MR (2016) Preventing Congenital Cytomegalovirus Infection: protection to a \u2018T\u2019. Trends Microbiol 24:170\u2013172","journal-title":"Trends Microbiol"},{"key":"472_CR100","first-page":"463","volume-title":"Cytomegaloviruses from molecular pathogenesis to intervention","author":"K Fr\u00fch","year":"2013","unstructured":"Fr\u00fch K, Malouli D, Oxford KL, Barry PA (2013) Non-human-primate models of cytomegalovirus infection, prevention, and therapy. In: Reddehase MJ (ed) Cytomegaloviruses From molecular pathogenesis to intervention. Caister Academic Press, Norfolk, pp 463\u2013496"},{"key":"472_CR101","doi-asserted-by":"publisher","unstructured":"McVoy, MA, Wang, JB, Dittmer, DP, Bierle, C, Swanson, EC, Fernandez-Alarcon, C, Hernandez-Alvarado, N, Zabeli, JC, Schleiss, MR (2016) Repair of a mutation disrupting the guinea pig cytomegalovirus pentameric complex acquired during fibroblast passage restores pathogenesis in immune suppressed guinea pigs and in the context of congenital infection. J Virol. doi:10.1128\/JVI.00320-16","DOI":"10.1128\/JVI.00320-16"},{"key":"472_CR102","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1007\/s00430-014-0346-1","volume":"203","author":"HW Doerr","year":"2014","unstructured":"Doerr HW, Berger A (2014) Vaccination against infectious diseases: what is promising? Med Microbiol Immunol 203:365\u2013371","journal-title":"Med Microbiol Immunol"},{"issue":"Suppl 2","key":"472_CR103","doi-asserted-by":"publisher","first-page":"B197","DOI":"10.1016\/j.vaccine.2012.10.074","volume":"31","author":"P Griffiths","year":"2013","unstructured":"Griffiths P, Plotkin S, Mocarski E, Pass R, Schleiss M, Krause P, Bialek S (2013) Desirability and feasibility of a vaccine against cytomegalovirus. Vaccine 31(Suppl 2):B197\u2013B203","journal-title":"Vaccine"},{"issue":"Suppl 4","key":"472_CR104","doi-asserted-by":"publisher","first-page":"S196","DOI":"10.1093\/cid\/cit587","volume":"57","author":"MA McVoy","year":"2013","unstructured":"McVoy MA (2013) Cytomegalovirus vaccines. Clin Infect Dis 57(Suppl 4):S196\u2013S199","journal-title":"Clin Infect Dis"},{"key":"472_CR105","doi-asserted-by":"publisher","first-page":"1032","DOI":"10.1016\/B978-1-4557-0090-5.00046-X","volume-title":"Vaccines","author":"MR Schleiss","year":"2013","unstructured":"Schleiss MR, Plotkin SA (2013) Cytomegalovirus vaccines. In: Plotkin SA, Orenstein WA, Offit PA (eds) Vaccines. Elsevier, Saunders, pp 1032\u20131041"},{"key":"472_CR106","doi-asserted-by":"publisher","first-page":"915","DOI":"10.1097\/INF.0b013e3181e0ce05","volume":"29","author":"EL Duryea","year":"2010","unstructured":"Duryea EL, Sanchez PJ, Sheffield JS, Jackson GL, Wendel GD, McElwee BS, Boney LF, Mallory MM, Owen KE, Stehel EK (2010) Maternal human immunodeficiency virus infection and congenital transmission of cytomegalovirus. Pediatr Infect Dis J 29:915\u2013918","journal-title":"Pediatr Infect Dis J"},{"key":"472_CR107","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1007\/s00430-015-0427-9","volume":"205","author":"A Reitter","year":"2016","unstructured":"Reitter A, Buxmann H, Haberl AE, Schlosser R, Kreibich M, Keppler OT, Berger A (2016) Incidence of CMV co-infection in HIV-positive women and their neonates in a tertiary referral centre: a cohort study. Med Microbiol Immunol 205:63\u201371","journal-title":"Med Microbiol Immunol"},{"key":"472_CR108","doi-asserted-by":"publisher","first-page":"1467","DOI":"10.1093\/cid\/ciu096","volume":"58","author":"S Manicklal","year":"2014","unstructured":"Manicklal S, van Niekerk AM, Kroon SM, Hutto C, Novak Z, Pati SK, Chowdhury N, Hsiao NY, Boppana SB (2014) Birth prevalence of congenital cytomegalovirus among infants of HIV-infected women on prenatal antiretroviral prophylaxis in South Africa. Clin Infect Dis 58:1467\u20131472","journal-title":"Clin Infect Dis"},{"key":"472_CR109","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1128\/jvi.70.1.78-83.1996","volume":"70","author":"TA Cha","year":"1996","unstructured":"Cha TA, Tom E, Kemble GW, Duke GM, Mocarski ES, Spaete RR (1996) Human cytomegalovirus clinical isolates carry at least 19 genes not found in laboratory strains. J Virol 70:78\u201383","journal-title":"J Virol"},{"key":"472_CR110","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1002\/jmv.1890400107","volume":"40","author":"B Weber","year":"1993","unstructured":"Weber B, Klinghardt U, Lux A, Braun W, Rabenau H, Doerr HW (1993) Detection of neutralizing antibodies against human cytomegalovirus: influence of strain variation. J Med Virol 40:28\u201334","journal-title":"J Med Virol"},{"key":"472_CR111","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1093\/infdis\/163.6.1229","volume":"163","author":"SW Chou","year":"1991","unstructured":"Chou SW, Dennison KM (1991) Analysis of interstrain variation in cytomegalovirus glycoprotein B sequences encoding neutralization-related epitopes. J Infect Dis 163:1229\u20131234","journal-title":"J Infect Dis"},{"key":"472_CR112","doi-asserted-by":"publisher","first-page":"1985","DOI":"10.1099\/0022-1317-72-8-1985","volume":"72","author":"J Darlington","year":"1991","unstructured":"Darlington J, Super M, Patel K, Grundy JE, Griffiths PD, Emery VC (1991) Use of the polymerase chain reaction to analyse sequence variation within a major neutralizing epitope of glycoprotein B (gp58) in clinical isolates of human cytomegalovirus. J Gen Virol 72:1985\u20131989","journal-title":"J Gen Virol"},{"key":"472_CR113","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1007\/s004300050055","volume":"186","author":"H Hebart","year":"1997","unstructured":"Hebart H, Greif M, Krause H, Kanz L, Jahn G, Muller CA, Einsele H (1997) Interstrain variation of immediate early DNA sequences and glycoprotein B genotypes in cytomegalovirus clinical isolates. Med Microbiol Immunol Berl 186:135\u2013138","journal-title":"Med Microbiol Immunol Berl"},{"key":"472_CR114","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1002\/rmv.438","volume":"14","author":"S Pignatelli","year":"2004","unstructured":"Pignatelli S, Dal MP, Rossini G, Landini MP (2004) Genetic polymorphisms among human cytomegalovirus (HCMV) wild-type strains. Rev Med Virol 14:383\u2013410","journal-title":"Rev Med Virol"},{"key":"472_CR115","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1007\/s00430-012-0244-3","volume":"202","author":"JU Vogel","year":"2013","unstructured":"Vogel JU, Otte J, Koch F, Gumbel H, Doerr HW, Cinatl J Jr (2013) Role of human cytomegalovirus genotype polymorphisms in AIDS patients with cytomegalovirus retinitis. Med Microbiol Immunol 202:37\u201347","journal-title":"Med Microbiol Immunol"},{"key":"472_CR116","doi-asserted-by":"publisher","first-page":"e1001344","DOI":"10.1371\/journal.ppat.1001344","volume":"7","author":"N Renzette","year":"2011","unstructured":"Renzette N, Bhattacharjee B, Jensen JD, Gibson L, Kowalik TF (2011) Extensive genome-wide variability of human cytomegalovirus in congenitally infected infants. PLoS Pathog 7:e1001344","journal-title":"PLoS Pathog"},{"key":"472_CR117","doi-asserted-by":"publisher","first-page":"E4120","DOI":"10.1073\/pnas.1501880112","volume":"112","author":"N Renzette","year":"2015","unstructured":"Renzette N, Pokalyuk C, Gibson L, Bhattacharjee B, Schleiss MR, Hamprecht K, Yamamoto AY, Mussi-Pinhata MM, Britt WJ, Jensen JD, Kowalik TF (2015) Limits and patterns of cytomegalovirus genomic diversity in humans. Proc Natl Acad Sci USA 112:E4120\u2013E4128","journal-title":"Proc Natl Acad Sci USA"},{"issue":"15","key":"472_CR118","doi-asserted-by":"publisher","first-page":"7673","DOI":"10.1128\/JVI.00578-15","volume":"89","author":"S Sijmons","year":"2015","unstructured":"Sijmons S, Thys K, Mbong NM, Van DE, Dvorak J, Van LM, Li G, Tachezy R, Busson L, Aerssens J, Van RM, Maes P (2015) High-throughput analysis of human cytomegalovirus genome diversity highlights the widespread occurrence of gene-disrupting mutations and pervasive recombination. J Virol 89(15):7673\u20137695","journal-title":"J Virol"},{"key":"472_CR119","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1007\/s00430-015-0411-4","volume":"204","author":"GW Wilkinson","year":"2015","unstructured":"Wilkinson GW, Davison AJ, Tomasec P, Fielding CA, Aicheler R, Murrell I, Seirafian S, Wang EC, Weekes M, Lehner PJ, Wilkie GS, Stanton RJ (2015) Human cytomegalovirus: taking the strain. Med Microbiol Immunol 204:273\u2013284","journal-title":"Med Microbiol Immunol"},{"key":"472_CR120","doi-asserted-by":"publisher","first-page":"e1003257","DOI":"10.1371\/journal.ppat.1003257","volume":"9","author":"J Siewiera","year":"2013","unstructured":"Siewiera J, El CH, Tabiasco J, Berrebi A, Cartron G, Le BP, Jabrane-Ferrat N (2013) Human cytomegalovirus infection elicits new decidual natural killer cell effector functions. PLoS Pathog 9:e1003257","journal-title":"PLoS Pathog"},{"key":"472_CR121","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/j.virol.2015.06.023","volume":"485","author":"Y Weisblum","year":"2015","unstructured":"Weisblum Y, Panet A, Zakay-Rones Z, Vitenshtein A, Haimov-Kochman R, Goldman-Wohl D, Oiknine-Djian E, Yamin R, Meir K, Amsalem H, Imbar T, Mandelboim O, Yagel S, Wolf DG (2015) Human cytomegalovirus induces a distinct innate immune response in the maternal-fetal interface. Virology 485:289\u2013296","journal-title":"Virology"},{"key":"472_CR122","doi-asserted-by":"publisher","first-page":"e1004100","DOI":"10.1371\/journal.ppat.1004100","volume":"10","author":"S Ebert","year":"2014","unstructured":"Ebert S, Becker M, Lemmermann NA, Buttner JK, Michel A, Taube C, Podlech J, Bohm V, Freitag K, Thomas D, Holtappels R, Reddehase MJ, Stassen M (2014) Mast cells expedite control of pulmonary murine cytomegalovirus infection by enhancing the recruitment of protective CD8 T cells to the lungs. PLoS Pathog 10:e1004100","journal-title":"PLoS Pathog"},{"key":"472_CR123","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1007\/s00430-015-0386-1","volume":"204","author":"J Podlech","year":"2015","unstructured":"Podlech J, Ebert S, Becker M, Reddehase MJ, Stassen M, Lemmermann NA (2015) Mast cells: innate attractors recruiting protective CD8 T cells to sites of cytomegalovirus infection. Med Microbiol Immunol 204:327\u2013334","journal-title":"Med Microbiol Immunol"},{"key":"472_CR124","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1007\/s00430-015-0403-4","volume":"204","author":"MM Brinkmann","year":"2015","unstructured":"Brinkmann MM, Dag F, Hengel H, Messerle M, Kalinke U, Cicin-Sain L (2015) Cytomegalovirus immune evasion of myeloid lineage cells. Med Microbiol Immunol 204:367\u2013382","journal-title":"Med Microbiol Immunol"},{"key":"472_CR125","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1007\/s12026-012-8304-8","volume":"54","author":"V Noriega","year":"2012","unstructured":"Noriega V, Redmann V, Gardner T, Tortorella D (2012) Diverse immune evasion strategies by human cytomegalovirus. Immunol Res 54:140\u2013151","journal-title":"Immunol Res"},{"key":"472_CR126","doi-asserted-by":"publisher","first-page":"4857","DOI":"10.1016\/j.jmb.2013.08.023","volume":"425","author":"L Amsler","year":"2013","unstructured":"Amsler L, Verweij MC, Defilippis VR (2013) The tiers and dimensions of evasion of the type I interferon response by human cytomegalovirus. J Mol Biol 425:4857\u20134871","journal-title":"J Mol Biol"},{"key":"472_CR127","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1126\/science.aac9475","volume":"351","author":"SG Hansen","year":"2016","unstructured":"Hansen SG, Wu HL, Burwitz BJ, Hughes CM, Hammond KB, Ventura AB, Reed JS, Gilbride RM, Ainslie E, Morrow DW, Ford JC, Selseth AN, Pathak R, Malouli D, Legasse AW, Axthelm MK, Nelson JA, Gillespie GM, Walters LC, Brackenridge S, Sharpe HR, Lopez CA, Fr\u00fch K, Korber BT, McMichael AJ, Gnanakaran S, Sacha JB, Picker LJ (2016) Broadly targeted CD8(+) T cell responses restricted by major histocompatibility complex E. Science 351:714\u2013720","journal-title":"Science"},{"key":"472_CR128","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1126\/science.1185350","volume":"328","author":"SG Hansen","year":"2010","unstructured":"Hansen SG, Powers CJ, Richards R, Ventura AB, Ford JC, Siess D, Axthelm MK, Nelson JA, Jarvis MA, Picker LJ, Fr\u00fch K (2010) Evasion of CD8+ T cells is critical for superinfection by cytomegalovirus. Science 328:102\u2013106","journal-title":"Science"},{"key":"472_CR129","first-page":"74","volume-title":"Cytomegaloviruses From Molecular Pathogenesis to Intervention","author":"L Pereira","year":"2013","unstructured":"Pereira L, Tabata T, Petitt M, Hoover JF (2013) Cytomegalovirus Replication in the Developing Human Placenta. In: Reddehase MJ (ed) Cytomegaloviruses From molecular pathogenesis to intervention. Caister Academic Press, Norfolk, pp 74\u201387"},{"key":"472_CR130","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1007\/s00281-014-0449-1","volume":"36","author":"Y Weisblum","year":"2014","unstructured":"Weisblum Y, Panet A, Haimov-Kochman R, Wolf DG (2014) Models of vertical cytomegalovirus (CMV) transmission and pathogenesis. Semin Immunopathol 36:615\u2013625","journal-title":"Semin Immunopathol"}],"container-title":["Medical Microbiology and Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00430-016-0472-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00430-016-0472-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00430-016-0472-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T05:05:27Z","timestamp":1744175127000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00430-016-0472-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,12]]},"references-count":130,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["472"],"URL":"https:\/\/doi.org\/10.1007\/s00430-016-0472-z","relation":{},"ISSN":["0300-8584","1432-1831"],"issn-type":[{"type":"print","value":"0300-8584"},{"type":"electronic","value":"1432-1831"}],"subject":[],"published":{"date-parts":[[2016,8,12]]},"assertion":[{"value":"29 July 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 August 2016","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 August 2016","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}