{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T18:23:03Z","timestamp":1749406983263,"version":"3.37.3"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2019,3,11]],"date-time":"2019-03-11T00:00:00Z","timestamp":1552262400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Microbiol Immunol"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1007\/s00430-019-00590-0","type":"journal-article","created":{"date-parts":[[2019,3,11]],"date-time":"2019-03-11T13:56:56Z","timestamp":1552312616000},"page":"693-702","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Discrimination between recent and non-recent HIV infections using routine diagnostic serological assays"],"prefix":"10.1007","volume":"208","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5270-7372","authenticated-orcid":false,"given":"Jaythoon","family":"Hassan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne","family":"Moran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivia","family":"Mason","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeff","family":"Connell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cillian","family":"De Gascun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,3,11]]},"reference":[{"issue":"10","key":"590_CR1","doi-asserted-by":"publisher","first-page":"5508","DOI":"10.3390\/v7102887","volume":"7","author":"S Moyo","year":"2015","unstructured":"Moyo S, Wilkinson E, Novitsky V et al (2015) Identifying recent HIV infections: from serological assays to genomics. Viruses 7(10):5508\u20135524. \n                    https:\/\/doi.org\/10.3390\/v7102887","journal-title":"Viruses"},{"issue":"12","key":"590_CR2","doi-asserted-by":"publisher","first-page":"e343","DOI":"10.1371\/journal.pmed.0040343","volume":"4","author":"J Sch\u00fcpbach","year":"2007","unstructured":"Sch\u00fcpbach J, Gebhardt MD, Tomasik Z et al (2007) Assessment of recent HIV-1 infection by a line immunoassay for HIV-1\/2 confirmation. PLoS Med 4(12):e343","journal-title":"PLoS Med"},{"issue":"8","key":"590_CR3","doi-asserted-by":"publisher","first-page":"e71662","DOI":"10.1371\/journal.pone.0071662","volume":"8","author":"J Sch\u00fcpbach","year":"2013","unstructured":"Sch\u00fcpbach J, Gebhardt MD, Scherrer AU et al (2013) Simple estimation of incident HIV infection rates in notification cohorts based on window periods of algorithms for evaluation of line-immunoassay result patterns. PLoS One 8(8):e71662. \n                    https:\/\/doi.org\/10.1371\/journal.pone.0071662","journal-title":"PLoS One"},{"key":"590_CR4","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1186\/1471-2334-11-254","volume":"11","author":"J Schupbach","year":"2011","unstructured":"Schupbach J, Bisset LR, Regenass S et al (2011) High specificity of line-immunoassay based algorithms for recent HIV-1 infection independent of viral subtype and stage of disease. BMC Infect Dis 11:254","journal-title":"BMC Infect Dis"},{"key":"590_CR5","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1186\/1471-2334-12-88","volume":"12","author":"J Schupbach","year":"2012","unstructured":"Schupbach J, Bisset LR, Gebhardt MD et al (2012) Diagnostic performance of line-immunoassay based algorithms for incident HIV-1 infection. BMC Infect Dis 12:88","journal-title":"BMC Infect Dis"},{"issue":"7","key":"590_CR6","doi-asserted-by":"publisher","first-page":"e0131828","DOI":"10.1371\/journal.pone.0131828","volume":"10","author":"J Sch\u00fcpbach","year":"2015","unstructured":"Sch\u00fcpbach J, Niederhauser C, Yerly S et al (2015) Decreasing proportion of recent infections among newly diagnosed HIV-1 cases in Switzerland, 2008 to 2013 based on line-immunoassay-based algorithms. PLoS One 10(7):e0131828. \n                    https:\/\/doi.org\/10.1371\/journal.pone.0131828","journal-title":"PLoS One"},{"key":"590_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1089\/aid.2009.0133","volume":"26","author":"X Wei","year":"2010","unstructured":"Wei X, Liu X, Dobbs T, Kuehl et al (2010) Development of two avidity-based assays to detect recent HIV type 1 seroconversion using a multisubtype gp41 recombinant protein. AIDS Res Hum Retrovirus 26:1\u201311","journal-title":"AIDS Res Hum Retrovirus"},{"key":"590_CR8","doi-asserted-by":"publisher","first-page":"e33328","DOI":"10.1371\/journal.pone.0033328","volume":"7","author":"YT Duong","year":"2012","unstructured":"Duong YT, Qiu M, De AK et al (2012) Detection of recent HIV-1 infection using a new limiting-antigen avidity assay: potential for HIV-1 incidence estimates and avidity maturation studies. PLoS One 7:e33328","journal-title":"PLoS One"},{"key":"590_CR9","unstructured":"Parekh B, Duong Y, Mavengere Y et al (2012) Performance of new LAg-Avidity EIA to measure HIV-1 incidence in a cross-sectional population: Swaziland HIV Incidence Measurement Survey (SHIMS). In: XIX international AIDS conference. Washington DC. July 22\u201327, Abstract #LBPE27"},{"key":"590_CR10","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1093\/aje\/153.10.925","volume":"153","author":"S Schwarcz","year":"2001","unstructured":"Schwarcz S, Kellogg T, McFarland W et al (2001) Differences in the temporal trends of HIV seroincidence and seroprevalence among sexually transmitted disease clinic patients, 1989\u20131998: application of the serological testing algorithm for recent HIV seroconversion. Am J Epidemiol 153:925\u2013934","journal-title":"Am J Epidemiol"},{"key":"590_CR11","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1097\/00002030-200201040-00014","volume":"16","author":"DM Machado","year":"2002","unstructured":"Machado DM, Delwart EL, Diza RS et al (2002) Use of the sensitive\/less-sensitive (detuned) EIA strategy for targeting genetic analysis of HIV-1 recently infected blood donors. AIDS 16:113\u2013119","journal-title":"AIDS"},{"issue":"2","key":"590_CR12","doi-asserted-by":"publisher","first-page":"e0114947","DOI":"10.1371\/journal.pone.0114947","volume":"10","author":"YT Duong","year":"2015","unstructured":"Duong YT, Kassanjee R, Welte A et al (2015) Recalibration of the limiting antigen avidity EIA to determine mean duration of recent infection in divergent HIV-1 subtypes. PLoS One 10(2):e0114947. \n                    https:\/\/doi.org\/10.1371\/journal.pone.0114947","journal-title":"PLoS One"},{"key":"590_CR13","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1136\/bmj.300.6719.223","volume":"300","author":"DG Seymour","year":"1990","unstructured":"Seymour DG, Green M, Vaz FG (1990) Making better decisions: construction of clinical scoring systems by the Spiegelhalter\u2013Knill\u2013Jones approach. BMJ 300:223\u2013226","journal-title":"BMJ"},{"key":"590_CR14","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.jclinepi.2007.02.012","volume":"1","author":"SF Chan","year":"2008","unstructured":"Chan SF, Deeks JJ, Macaskill P, Irwig L (2008) Three methods to construct predictive models using logistic regression and likelihood ratios to facilitate adjustment for pretest probability give similar results. J Clin Epidemiol 1:52\u201363","journal-title":"J Clin Epidemiol"},{"key":"590_CR15","doi-asserted-by":"publisher","first-page":"2610","DOI":"10.1128\/JCM.02115-10","volume":"49","author":"B Suligoi","year":"2011","unstructured":"Suligoi B, Rodella A, Raimondo M et al (2011) Avidity index for anti-HIV antibodies: comparison between third- and fourth-generation automated immunoassays. J Clin Micro 49:2610\u20132613","journal-title":"J Clin Micro"},{"issue":"40","key":"590_CR16","doi-asserted-by":"publisher","first-page":"30036","DOI":"10.2807\/1560-7917.ES.2015.20.40.30036","volume":"20","author":"C Glese","year":"2015","unstructured":"Glese C, Igoe D, Gibbons Z, Hurley C, Stokes S, McNamara S, Ennis O, O\u2019Donnell K, Keenan E, De Gascun C, Lyons F, Ward M, Danis K, Glynn R, Waters A, Fitzgerald M, On behalf of the outbreak control team (2015). Injection of new psychoactive substance snow blow associated with recently acquired HIV infections among homeless people who inject drugs in Dublin, Ireland. Eurosurveillance 20(40):30036","journal-title":"Eurosurveillance"},{"key":"590_CR17","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1093\/infdis\/jix225","volume":"216","author":"SM Keating","year":"2017","unstructured":"Keating SM, Pilcher CD, Jain V et al (2017) HIV antibody level as a marker of HIV persistence and low level viral replication. J Infect Dis 216:72\u201381","journal-title":"J Infect Dis"},{"issue":"4","key":"590_CR18","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1089\/aid.2016.0105","volume":"33","author":"SK Wendel","year":"2017","unstructured":"Wendel SK, Longosz AF, Eshleman SH et al (2017) Short communication: the impact of viral suppression and viral breakthrough on limited-antigen avidity assay results in individuals with clade B HIV infection. AIDS Res Hum Retrovirus 33(4):325\u2013327. \n                    https:\/\/doi.org\/10.1089\/AID.2016.0105","journal-title":"AIDS Res Hum Retrovirus"},{"issue":"5","key":"590_CR19","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.1086\/315088","volume":"180","author":"A Manns","year":"1999","unstructured":"Manns A, Miley WJ, Wilks RJ et al (1999) Quantitative proviral DNA and antibody levels in the natural history of HTLV-I infection. J Infect Dis 180(5):1487\u20131493","journal-title":"J Infect Dis"},{"issue":"5","key":"590_CR20","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1097\/QAI.0000000000001537","volume":"76","author":"E Grebe","year":"2017","unstructured":"Grebe E, Welte A, Hall J et al (2017) Infection staging and incidence surveillance applications of high dynamic range diagnostic immune-assay platforms. J Acquir Immune Defic Syndromes 76(5):547\u2013555","journal-title":"J Acquir Immune Defic Syndromes"}],"container-title":["Medical Microbiology and Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00430-019-00590-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00430-019-00590-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00430-019-00590-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,10]],"date-time":"2020-03-10T00:12:42Z","timestamp":1583799162000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00430-019-00590-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,11]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["590"],"URL":"https:\/\/doi.org\/10.1007\/s00430-019-00590-0","relation":{},"ISSN":["0300-8584","1432-1831"],"issn-type":[{"type":"print","value":"0300-8584"},{"type":"electronic","value":"1432-1831"}],"subject":[],"published":{"date-parts":[[2019,3,11]]},"assertion":[{"value":"3 October 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 March 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 March 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"For this type of study, formal consent is not required.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}