{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T15:22:59Z","timestamp":1773156179589,"version":"3.50.1"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2008,2,27]],"date-time":"2008-02-27T00:00:00Z","timestamp":1204070400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1007\/s00431-008-0679-0","type":"journal-article","created":{"date-parts":[[2008,2,26]],"date-time":"2008-02-26T13:20:10Z","timestamp":1204032010000},"page":"1455-1458","source":"Crossref","is-referenced-by-count":29,"title":["Central precocious puberty and growth hormone deficiency in a boy with Prader-Willi syndrome"],"prefix":"10.1007","volume":"167","author":[{"given":"Antonino","family":"Crin\u00f2","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Girolamo","family":"Di Giorgio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riccardo","family":"Schiaffini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Fierabracci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina","family":"Spera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Maggioni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guido Castelli","family":"Gattinara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,2,27]]},"reference":[{"key":"679_CR1","first-page":"1085","volume":"58","author":"American Society of Human Genetics\/American College of Medical Genetics Test and Technology Transfer Committee","year":"1996","unstructured":"American Society of Human Genetics\/American College of Medical Genetics Test and Technology Transfer Committee (1996) Diagnostic testing for Prader-Willi and Angelman syndromes: report of the ASHG\/ACMG test and technology transfer committee. Am J Hum Genet 58:1085\u20131088","journal-title":"Am J Hum Genet"},{"key":"679_CR2","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1093\/humrep\/12.4.746","volume":"12","author":"RA Anderson","year":"1997","unstructured":"Anderson RA, Wallace EM, Groome NP, Bellis AJ, Wu FCW (1997) Physiological relationships between inhibin B, follicle stimulating hormone secretion and spermatogenesis in normal men and response to gonadotropin suppression by exogenous testosterone. Hum Reprod 12:746\u2013751","journal-title":"Hum Reprod"},{"issue":"6","key":"679_CR3","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1210\/edrv.22.6.0447","volume":"22","author":"P Burman","year":"2001","unstructured":"Burman P, Ritzen EM, Lindgren AC (2001) Endocrine dysfunction in Prader-Willi syndrome: a review with special reference to GH. Endocr Rev 22(6):787\u2013799","journal-title":"Endocr Rev"},{"key":"679_CR4","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1007\/BF03343684","volume":"23","author":"A Corrias","year":"2000","unstructured":"Corrias A, Bellone J, Beccaria L, Bosio L, Trifiro G, Livieri C, Ragusa L, Salvatoni A, Andreo M, Ciampalini P, Tonini G, Crino A; Genetic obesity study group of Italian society of paediatric endocrinology and diabetology (SIEDP) (2000) GH\/IGF-I axis in Prader-Willi syndrome: evaluation of IGF-I levels and of the somatotroph responsiveness to various provocative stimuli. J Endocrinol Invest 23:84\u201389","journal-title":"J Endocrinol Invest"},{"issue":"5","key":"679_CR5","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s00431-002-1132-4","volume":"162","author":"A Crin\u00f2","year":"2003","unstructured":"Crin\u00f2 A, Schiaffini R, Ciampalini P, Spera S, Beccaria L, Benzi F, Bosio L, Corrias A, Gargantini L, Salvatoni A, Tonini G, Trifiro G, Livieri C; Genetic obesity study group of Italian society of paediatric endocrinology and diabetology (SIEDP) (2003) Hypogonadism and pubertal development in Prader-Willi syndrome. Eur J Pediatr 162(5):327\u2013333","journal-title":"Eur J Pediatr"},{"key":"679_CR6","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1210\/jc.2005-0902","volume":"91","author":"U Eiholzer","year":"2006","unstructured":"Eiholzer U, l\u2019Allemand D, Rousson V, Schlumpf, Gasser T, Girard J, Gr\u00fcters A, Simoni (2006) Hypothalamic and gonadal components of hypogonadism in boys with Prader-Labhart-Willi Syndrome. J Clin Endocrinol Metab 91:892\u2013898","journal-title":"J Clin Endocrinol Metab"},{"key":"679_CR7","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.tem.2003.11.003","volume":"15","author":"A Goldstone","year":"2004","unstructured":"Goldstone A (2004) Prader-Willi syndrome: advanced in genetics, pathophysiology and treatment. Trends Endocrinol Metab 15:12\u201320","journal-title":"Trends Endocrinol Metab"},{"issue":"1","key":"679_CR8","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1385\/EP:11:1:69","volume":"11","author":"S Grosso","year":"2000","unstructured":"Grosso S, Anichini C, Berardi R, Balestri P, Pucci L, Morgese G (2000) Central precocious puberty and abnormal chromosomal patterns. Endocr Pathol 11(1):69\u201375","journal-title":"Endocr Pathol"},{"key":"679_CR9","unstructured":"Grugni G, Morabito F, Crin\u00f2 A (2003) Gonadal function and its disorders in simple obesity and in Prader-Willy syndrome In: Eiholzer U, Allemand Dl\u2019, Zipf WB (eds) Prader Willy syndrome as a model for obesity. International Symposium, Zurich, 2002. Karger, Basel, pp 140\u2013155"},{"key":"679_CR10","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1542\/peds.91.2.398","volume":"91","author":"VA Holm","year":"1993","unstructured":"Holm VA, Cassidy SB, Butler MG, Hanchett JH, Greenswag LR, Whitman BY, Greenberg F (1993) Prader-Willi syndrome: consensus diagnostic criteria. Pediatrics 91:398\u2013402","journal-title":"Pediatrics"},{"key":"679_CR11","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1111\/j.1651-2227.1978.tb16258.x","volume":"67","author":"R Kauli","year":"1978","unstructured":"Kauli R, Prager-Lewin R, Laron Z (1978) Pubertal development in the Prader-Labhart-Willi syndrome. Acta Paediatr Scand 67:763\u2013767","journal-title":"Acta Paediatr Scand"},{"issue":"1","key":"679_CR12","first-page":"71S","volume":"10","author":"PDK Lee","year":"2000","unstructured":"Lee PDK, Allen DB, Angulo MA, Cappa M, Carrel AL, Castro-Magana M, Chiumello G, Davies PSW, Eiholzer U, Grugni G, Hauffa BP, Hintz RL, Lammer C, Mogul HR, Myers SE, Partsch C-J, Pescovitz OH, Ritzen EM, Rosenfeld RG, Sipila I, Wilson DM (2000) Consensus statement\u2014Prader-Willi syndrome: growth hormone (GH)\/insulin-like growth factor axis deficiency and GH treatment. Endocrinologist 10(suppl 1\u20134):71S\u201374S","journal-title":"Endocrinologist"},{"issue":"11","key":"679_CR13","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1111\/j.1651-2227.1999.tb01037.x","volume":"88","author":"K Linnemann","year":"1999","unstructured":"Linnemann K, Schroder C, Mix M, Kruger G, Fusch C (1999) Prader-Labhart-Willi syndrome with central precocious puberty and empty sella syndrome. Acta Paediatr 88(11):1295\u20131297","journal-title":"Acta Paediatr"},{"key":"679_CR14","doi-asserted-by":"crossref","unstructured":"Miller JL, Goldstone AP, Couch JA, Shuster J, He G, Driscoll DJ, Liu Y, Schmalfuss IM (2007) Pituitary abnormalities in Prader-Willi syndrome and early onset morbid obesity. Am J Med Genet A. DOI 10.1002\/ajmg.a.31677","DOI":"10.1002\/ajmg.a.31677"},{"issue":"2","key":"679_CR15","first-page":"P3","volume":"62","author":"A Rudzka-Kocjan","year":"2004","unstructured":"Rudzka-Kocjan A, Ginalska-Malinowska M, Lecka A, Gajewska M (2004) A central precocious puberty (CPP) in a boy with Prader-Willi syndrome (PWS). Horm Res 62(suppl 2):P3\u2013P183 (abstract)","journal-title":"Horm Res"},{"key":"679_CR16","first-page":"279","volume":"53","author":"M Tauber","year":"2000","unstructured":"Tauber M, Barbeau C, Jouret B, Pienkowski C, Malzac P, Moncla A, Rochiccioli P (2000) Auxological and endocrine evolution of 28 children with Prader-Willi syndrome: effect of GH therapy in 14 children. Horm Res 53:279\u2013287","journal-title":"Horm Res"},{"issue":"4","key":"679_CR17","first-page":"373","volume":"39","author":"M Vanelli","year":"1984","unstructured":"Vanelli M, Bernasconi S, Caronna N, Virdis R, Terzi C, Giovannelli G (1984) Precocious puberty in a male with Prader-Labhart-Willi syndrome. Helv Paediatr Acta 39(4):373\u2013377","journal-title":"Helv Paediatr Acta"},{"issue":"2","key":"679_CR18","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1055\/s-2008-1034445","volume":"193","author":"JN Walterspiel","year":"1981","unstructured":"Walterspiel JN, Wolff J, Heinze E (1981) Prader-Labhart-Willi syndrome with precocious puberty. Klin Padiatr 193(2):120\u2013121","journal-title":"Klin Padiatr"},{"key":"679_CR19","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1136\/jmg.38.11.792","volume":"38","author":"JE Whittington","year":"2001","unstructured":"Whittington JE, Holland AJ, Webb T, Butler J, Clarke D, Boer H (2001) Population prevalence and estimated birth incidence and mortality rate for people with Prader-Willi syndrome in one UK health region. J Med Genet 38:792\u2013798","journal-title":"J Med Genet"}],"container-title":["European Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-008-0679-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00431-008-0679-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-008-0679-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T17:31:38Z","timestamp":1684258298000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00431-008-0679-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2,27]]},"references-count":19,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["679"],"URL":"https:\/\/doi.org\/10.1007\/s00431-008-0679-0","relation":{},"ISSN":["0340-6199","1432-1076"],"issn-type":[{"value":"0340-6199","type":"print"},{"value":"1432-1076","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,2,27]]}}}