{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:26:46Z","timestamp":1761708406842},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2009,8,25]],"date-time":"2009-08-25T00:00:00Z","timestamp":1251158400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"published-print":{"date-parts":[[2010,4]]},"DOI":"10.1007\/s00431-009-1051-8","type":"journal-article","created":{"date-parts":[[2009,8,24]],"date-time":"2009-08-24T01:38:42Z","timestamp":1251077922000},"page":"501-504","source":"Crossref","is-referenced-by-count":5,"title":["Virilizing adrenocortical carcinoma in a child with Turner syndrome and somatic TP53 gene mutation"],"prefix":"10.1007","volume":"169","author":[{"given":"Jung-Hee","family":"Ko","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyo Sung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong","family":"Hong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Soon","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,8,25]]},"reference":[{"key":"1051_CR1","doi-asserted-by":"crossref","first-page":"14440","DOI":"10.1073\/pnas.96.25.14440","volume":"96","author":"L Carrel","year":"1999","unstructured":"Carrel L, Cottle AA, Goglin KC et al (1999) A first-generation X-inactivation profile of the human X chromosome. Proc Natl Acad Sci USA 96:14440\u201314444","journal-title":"Proc Natl Acad Sci USA"},{"key":"1051_CR2","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/S0022-5347(05)66150-2","volume":"166","author":"FL Chang","year":"2001","unstructured":"Chang FL, Lai MD (2001) Various forms of mutant p53 confer sensitivity to cisplatin and doxorubicin in bladder cancer cells. J Urol 166:304\u2013310","journal-title":"J Urol"},{"key":"1051_CR3","first-page":"120","volume":"23","author":"M Elsheikh","year":"2002","unstructured":"Elsheikh M, Dunger DB, Conway GS et al (2002) Turner's syndrome in adulthood. Endocr Rev 23:120\u2013140","journal-title":"Endocr Rev"},{"key":"1051_CR4","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1136\/jmg.2004.030551","volume":"43","author":"BC Figueiredo","year":"2006","unstructured":"Figueiredo BC, Sandrini R, Zambetti GP et al (2006) Penetrance of adrenocortical tumours associated with the germline TP53 R337H mutation. J Med Genet 43:91\u201396","journal-title":"J Med Genet"},{"key":"1051_CR5","volume-title":"Radiographic atlas of skeletal development of the hand and wrist","author":"WW Greulich","year":"1959","unstructured":"Greulich WW, Pyle SI (1959) Radiographic atlas of skeletal development of the hand and wrist, 2nd edn. Stanford University Press, Stanford","edition":"2"},{"key":"1051_CR6","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.jpedsurg.2007.12.022","volume":"43","author":"AM Hanna","year":"2008","unstructured":"Hanna AM, Pham TH, Askegard-Giesmann JR et al (2008) Outcome of adrenocortical tumors in children. J Pediatr Surg 43:843\u2013849","journal-title":"J Pediatr Surg"},{"key":"1051_CR7","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1017\/S0003480097006507","volume":"61","author":"P Jacobs","year":"1997","unstructured":"Jacobs P, Dalton P, James R et al (1997) Turner syndrome: a cytogenetic and molecular study. Ann Hum Genet 61:471\u2013483","journal-title":"Ann Hum Genet"},{"key":"1051_CR8","doi-asserted-by":"crossref","first-page":"15056","DOI":"10.1073\/pnas.0607286103","volume":"103","author":"AC Joerger","year":"2006","unstructured":"Joerger AC, Ang HC, Fersht AR (2006) Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci USA 103:15056\u201315061","journal-title":"Proc Natl Acad Sci USA"},{"key":"1051_CR9","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/S1043-2760(02)00602-1","volume":"13","author":"CE Keegan","year":"2002","unstructured":"Keegan CE, Hammer GD (2002) Recent insights into organogenesis of the adrenal cortex. Trends Endocrinol Metab 13:200\u2013208","journal-title":"Trends Endocrinol Metab"},{"key":"1051_CR10","first-page":"1491","volume":"75","author":"G Lashansky","year":"1992","unstructured":"Lashansky G, Saenger P, Dimartino-Nardi J et al (1992) Normative data for the steroidogenic response of mineralocorticoids and their precursors to adrenocorticotropin in a healthy pediatric population. J Clin Endocrinol Metab 75:1491\u20131496","journal-title":"J Clin Endocrinol Metab"},{"key":"1051_CR11","first-page":"1317","volume":"82","author":"AC Latronico","year":"1997","unstructured":"Latronico AC, Chrousos GP (1997) Extensive personal experience: adrenocortical tumors. J Clin Endocrinol Metab 82:1317\u20131324","journal-title":"J Clin Endocrinol Metab"},{"key":"1051_CR12","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.leukres.2007.06.004","volume":"32","author":"KN Manola","year":"2008","unstructured":"Manola KN, Sambani C, Karakasis D et al (2008) Leukemias associated with Turner syndrome: report of three cases and review of the literature. Leuk Res 32:481\u2013486","journal-title":"Leuk Res"},{"key":"1051_CR13","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1200\/JCO.2004.08.085","volume":"22","author":"E Michalkiewicz","year":"2004","unstructured":"Michalkiewicz E, Sandrini R, Figueiredo B et al (2004) Clinical and outcome characteristics of children with adrenocortical tumors: a report from the International Pediatric Adrenocortical Tumor Registry. J Clin Oncol 22:838\u2013845","journal-title":"J Clin Oncol"},{"key":"1051_CR14","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0165-4608(85)90241-9","volume":"16","author":"H Ochi","year":"1985","unstructured":"Ochi H, Takeuchi J, Sandberg AA (1985) Multiple cancers in a Turner's syndrome with 45,X\/46,XXp-\/46,XX\/47,XXX karyotype. Cancer Genet Cytogenet 16:335\u2013339","journal-title":"Cancer Genet Cytogenet"},{"key":"1051_CR15","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1038\/sj.onc.1210302","volume":"26","author":"A Petitjean","year":"2007","unstructured":"Petitjean A, Achatz MI, Borresen-Dale AL et al (2007) TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes. Oncogene 26:2157\u20132165","journal-title":"Oncogene"},{"key":"1051_CR16","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1136\/jmg.35.4.328","volume":"35","author":"EK Pivnick","year":"1998","unstructured":"Pivnick EK, Furman WL, Velagaleti GV et al (1998) Simultaneous adrenocortical carcinoma and ganglioneuroblastoma in a child with Turner syndrome and germline p53 mutation. J Med Genet 35:328\u2013332","journal-title":"J Med Genet"},{"key":"1051_CR17","doi-asserted-by":"crossref","first-page":"9330","DOI":"10.1073\/pnas.161479898","volume":"98","author":"RC Ribeiro","year":"2001","unstructured":"Ribeiro RC, Sandrini F, Figueiredo B et al (2001) An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma. Proc Natl Acad Sci USA 98:9330\u20139335","journal-title":"Proc Natl Acad Sci USA"},{"key":"1051_CR18","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/j.ejca.2004.01.031","volume":"40","author":"RC Ribeiro","year":"2004","unstructured":"Ribeiro RC, Figueiredo B (2004) Childhood adrenocortical tumours. Eur J Cancer 40:1117\u20131126","journal-title":"Eur J Cancer"},{"key":"1051_CR19","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/pbc.20318","volume":"45","author":"C Rodriguez-Galindo","year":"2005","unstructured":"Rodriguez-Galindo C, Figueiredo BC, Zambetti GP et al (2005) Biology, clinical characteristics, and management of adrenocortical tumors in children. Pediatr Blood Cancer 45:265\u2013273","journal-title":"Pediatr Blood Cancer"},{"key":"1051_CR20","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1136\/jmg.2008.059568","volume":"45","author":"A Russell-Swetek","year":"2008","unstructured":"Russell-Swetek A, West AN, Mintern JE et al (2008) Identification of a novel TP53 germline mutation E285V in a rare case of paediatric adrenocortical carcinoma and choroid plexus carcinoma. J Med Genet 45:603\u2013606","journal-title":"J Med Genet"},{"key":"1051_CR21","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S1470-2045(08)70033-0","volume":"9","author":"MJ Schoemaker","year":"2008","unstructured":"Schoemaker MJ, Swerdlow AJ, Higgins CD et al (2008) Cancer incidence in women with Turner syndrome in Great Britain: a national cohort study. Lancet Oncol 9:239\u2013246","journal-title":"Lancet Oncol"},{"key":"1051_CR22","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1136\/adc.51.3.170","volume":"51","author":"JM Tanner","year":"1976","unstructured":"Tanner JM, Whitehouse RH (1976) Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty. Arch Dis Child 51:170\u2013179","journal-title":"Arch Dis Child"},{"key":"1051_CR23","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1093\/jnci\/86.22.1707","volume":"86","author":"J Wagner","year":"1994","unstructured":"Wagner J, Portwine C, Rabin K et al (1994) High frequency of germline p53 mutations in childhood adrenocortical cancer. J Natl Cancer Inst 86:1707\u20131710","journal-title":"J Natl Cancer Inst"},{"key":"1051_CR24","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1002\/(SICI)1097-0142(20000215)88:4<711::AID-CNCR1>3.0.CO;2-W","volume":"88","author":"BL Wajchenberg","year":"2000","unstructured":"Wajchenberg BL, Albergaria Pereira MA, Medonca BB et al (2000) Adrenocortical carcinoma: clinical and laboratory observations. Cancer 88:711\u2013736","journal-title":"Cancer"},{"key":"1051_CR25","doi-asserted-by":"crossref","first-page":"8438","DOI":"10.1073\/pnas.96.15.8438","volume":"96","author":"KB Wong","year":"1999","unstructured":"Wong KB, DeDecker BS, Freund SM et al (1999) Hot-spot mutants of p53 core domain evince characteristic local structural changes. Proc Natl Acad Sci USA 96:8438\u20138442","journal-title":"Proc Natl Acad Sci USA"},{"key":"1051_CR26","doi-asserted-by":"crossref","first-page":"447","DOI":"10.2169\/internalmedicine.48.1157","volume":"48","author":"M Yamazaki","year":"2009","unstructured":"Yamazaki M, Sato A, Nishio S et al (2009) Acromegaly accompanied by Turner syndrome with 47,XXX\/45,X\/46,XX mosaicism. Intern Med 48:447\u2013453","journal-title":"Intern Med"}],"container-title":["European Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-009-1051-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00431-009-1051-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-009-1051-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T22:26:08Z","timestamp":1559082368000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00431-009-1051-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8,25]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,4]]}},"alternative-id":["1051"],"URL":"https:\/\/doi.org\/10.1007\/s00431-009-1051-8","relation":{},"ISSN":["0340-6199","1432-1076"],"issn-type":[{"value":"0340-6199","type":"print"},{"value":"1432-1076","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,8,25]]}}}