{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T06:52:14Z","timestamp":1787899934195,"version":"build-2784847793"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2015,1,10]],"date-time":"2015-01-10T00:00:00Z","timestamp":1420848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2015,1,10]],"date-time":"2015-01-10T00:00:00Z","timestamp":1420848000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.1007\/s00431-014-2483-3","type":"journal-article","created":{"date-parts":[[2015,1,9]],"date-time":"2015-01-09T02:27:29Z","timestamp":1420770449000},"page":"919-924","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["Characteristics and outcomes of human parechovirus infection in infants (2008\u20132012)"],"prefix":"10.1007","volume":"174","author":[{"given":"Stefania","family":"Vergnano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seilesh","family":"Kadambari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrina","family":"Whalley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esse N","family":"Menson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria","family":"Martinez-Alier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehrengise","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emile","family":"Sanchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul T","family":"Heath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hermione","family":"Lyall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,1,10]]},"reference":[{"issue":"2","key":"2483_CR1","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1086\/498905","volume":"42","author":"KS Benschop","year":"2006","unstructured":"Benschop KS, Schinkel J, Minnaar RP, Pajkrt D, Spanjerberg L, Kraakman HC, Berkhout B, Zaaijer HL, Beld MG, Wolthers KC (2006) Human parechovirus infections in Dutch children and the association between serotype and disease severity. Clin Infect Dis 42(2):204\u2013210","journal-title":"Clin Infect Dis"},{"issue":"12","key":"2483_CR2","doi-asserted-by":"publisher","first-page":"3965","DOI":"10.1128\/JCM.01379-08","volume":"46","author":"K Benschop","year":"2008","unstructured":"Benschop K, Thomas X, Serpenti C, Molenkamp R, Wolthers K (2008) High prevalence of human parechovirus (HPeV) genotypes in the Amsterdam region and identification of specific HPeV variants by direct genotyping of stool samples. J Clin Microbiol 46(12):3965\u20133970","journal-title":"J Clin Microbiol"},{"issue":"2","key":"2483_CR3","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.diagmicrobio.2010.05.016","volume":"68","author":"K Benschop","year":"2010","unstructured":"Benschop K, Minnaar R, Koen G, van Eijk H, Dijkman K, Westerhuis B, Molenkamp R, Wolthers K (2010) Detection of human enterovirus and human parechovirus (HPeV) genotypes from clinical stool samples: polymerase chain reaction and direct molecular typing, culture characteristics, and serotyping. Diagn Microbiol Infect Dis 68(2):166\u2013173","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"1","key":"2483_CR4","doi-asserted-by":"publisher","first-page":"103","DOI":"10.3201\/eid1101.040606","volume":"11","author":"G Boivin","year":"2005","unstructured":"Boivin G, Abed Y, Boucher FD (2005) Human parechovirus 3 and neonatal infections. Emerg Infect Dis 11(1):103\u2013105","journal-title":"Emerg Infect Dis"},{"issue":"2","key":"2483_CR5","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1016\/j.jcv.2013.07.017","volume":"58","author":"SC de Crom","year":"2013","unstructured":"de Crom SC, Obihara CC, de Moor RA, Veldkamp EJ, van Furth AM, Rossen JW (2013) Prospective comparison of the detection rates of human enterovirus and parechovirus RT-qPCR and viral culture in different pediatric specimens. J Clin Virol 58(2):449\u2013454","journal-title":"J Clin Virol"},{"issue":"1","key":"2483_CR6","doi-asserted-by":"publisher","first-page":"83","DOI":"10.3201\/eid2001.130569","volume":"20","author":"TK Fischer","year":"2014","unstructured":"Fischer TK, Midgley S, Dalgaard C, Nielsen AY (2014) Human parechovirus infection, Denmark. Emerg Infect Dis 20(1):83\u201387","journal-title":"Emerg Infect Dis"},{"issue":"12","key":"2483_CR7","doi-asserted-by":"publisher","first-page":"1753","DOI":"10.1086\/599094","volume":"199","author":"H Harvala","year":"2009","unstructured":"Harvala H, Robertson I, Chieochansin T, McWilliam Leitch EC, Templeton K, Simmonds P (2009) Specific association of human parechovirus type 3 with sepsis and fever in young infants, as identified by direct typing of cerebrospinal fluid samples. J Infect Dis 199(12):1753\u20131760","journal-title":"J Infect Dis"},{"issue":"1","key":"2483_CR8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jcv.2009.03.009","volume":"45","author":"H Harvala","year":"2009","unstructured":"Harvala H, Simmonds P (2009) Human parechoviruses: biology, epidemiology and clinical significance. J Clin Virol 45(1):1\u20139","journal-title":"J Clin Virol"},{"issue":"5","key":"2483_CR9","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1002\/jmv.22023","volume":"83","author":"H Harvala","year":"2011","unstructured":"Harvala H, McLeish N, Kondracka J, McIntyre CL, McWilliam Leitch EC, Templeton K, Simmonds P (2011) Comparison of human parechovirus and enterovirus detection frequencies in cerebrospinal fluid samples collected over a 5-year period in Edinburgh: HPeV type 3 identified as the most common picornavirus type. J Med Virol 83(5):889\u2013896","journal-title":"J Med Virol"},{"issue":"15","key":"2483_CR10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2807\/1560-7917.ES2014.19.15.20772","volume":"19","author":"H Harvala","year":"2014","unstructured":"Harvala H, Calvert J, Van Nguyen D, Clasper L, Gadsby N, Molyneaux P, Templeton K, McWilliams Leitch C, Simmonds P (2014) Comparison of diagnostic clinical samples and environmental sampling for enterovirus and parechovirus surveillance in Scotland, 2010 to 2012. Eur Surveill 19(15):1\u20139","journal-title":"Eur Surveill"},{"issue":"10","key":"2483_CR11","doi-asserted-by":"publisher","first-page":"2683","DOI":"10.1128\/JCM.00086-10","volume":"48","author":"M Ito","year":"2010","unstructured":"Ito M, Yamashita T, Tsuzuki H, Kabashima Y, Hasegawa A, Nagaya S, Kawaguchi M, Kobayashi S, Fujiura A, Sakae K, Minagawa H (2010) Detection of human parechoviruses from clinical stool samples in Aichi, Japan. J Clin Microbiol 48(10):2683\u20132688","journal-title":"J Clin Microbiol"},{"key":"2483_CR12","doi-asserted-by":"crossref","unstructured":"Kadambari S, Bukasa A, Okike IO, Pebody R, Brown D, Gallimore C, Xerry J, Sharland M, Ladhani SN (2014) Enterovirus infections in England and Wales, 2000\u20132011: the impact of increased molecular diagnostics. Clin Microbiol Infect [Epub ahead of print]","DOI":"10.1111\/1469-0691.12753"},{"issue":"4","key":"2483_CR13","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/j.jinf.2014.05.012","volume":"69","author":"S Kadambari","year":"2014","unstructured":"Kadambari S, Okike I, Ribeiro S, Ramsay ME, Heath PT, Sharland M, Ladhani SN (2014) Seven-fold increase in viral meningo-encephalitis reports in England and Wales during 2004\u20132013. J Infect 69(4):326\u2013332","journal-title":"J Infect"},{"issue":"6","key":"2483_CR14","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1111\/j.1469-0691.2009.02915.x","volume":"16","author":"L Ninove","year":"2010","unstructured":"Ninove L, Tan C, Nougairede A, Zandotti C, Richet H, Charrel R, de Lamballerie X (2010) Impact of diagnostic procedures on patient management and hospitalization cost during the 2000 and 2005 enterovirus epidemics in Marseilles, France. Clin Microbiol Infect 16(6):651\u2013656","journal-title":"Clin Microbiol Infect"},{"issue":"12","key":"2483_CR15","doi-asserted-by":"crossref","first-page":"3928","DOI":"10.1128\/JCM.37.12.3928-3933.1999","volume":"37","author":"MS Oberste","year":"1999","unstructured":"Oberste MS, Maher K, Kennett ML, Campbell JJ, Carpenter MS, Schnurr D, Pallansch MA (1999) Molecular epidemiology and genetic diversity of echovirus type 30 (E30): genotypes correlate with temporal dynamics of E30 isolation. J Clin Microbiol 37(12):3928\u20133933","journal-title":"J Clin Microbiol"},{"issue":"20","key":"2483_CR16","doi-asserted-by":"publisher","first-page":"2680","DOI":"10.1001\/jama.283.20.2680","volume":"283","author":"C Ramers","year":"2000","unstructured":"Ramers C, Billman G, Hartin M, Ho S, Sawyer MH (2000) Impact of a diagnostic cerebrospinal fluid enterovirus polymerase chain reaction test on patient management. JAMA 283(20):2680\u20132685","journal-title":"JAMA"},{"issue":"20","key":"2483_CR17","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1097\/00006454-200204000-00005","volume":"21","author":"CC Robinson","year":"2002","unstructured":"Robinson CC, Willis M, Meagher A et al (2002) Impact of rapid polymerase chain reaction results on management of pediatric patients with enteroviral meningitis. Pediatr Infect Dis J 21(20):283\u2013286","journal-title":"Pediatr Infect Dis J"},{"issue":"4","key":"2483_CR18","first-page":"2884","volume":"46","author":"CC Robinson","year":"2008","unstructured":"Robinson CC, Willis M, Meagher A, Gieseker KE, Rotbart H, Glod\u00e9 MP (2008) Prevalence of human parechovirus in the Netherlands in 2000 to 2007. J Clin Microbiol 46(4):2884\u20132889","journal-title":"J Clin Microbiol"},{"issue":"3","key":"2483_CR19","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1002\/ana.21445","volume":"64","author":"MA Verboon-Maciolek","year":"2008","unstructured":"Verboon-Maciolek MA, Groenendaal F, Hahn CD, Hellmann J, van Loon AM, Boivin G, de Vries LS (2008) Human parechovirus causes encephalitis with white matter injury in neonates. Ann Neurol 64(3):266\u2013273","journal-title":"Ann Neurol"},{"issue":"3","key":"2483_CR20","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1086\/589752","volume":"47","author":"KC Wolthers","year":"2008","unstructured":"Wolthers KC, Benschop KS, Schinkel J, Molenkamp R, Bergevoet RM, Spijkerman IJ, Kraakman HC, Pajkrt D (2008) Human parechoviruses as an important viral cause of sepsislike illness and meningitis in young children. Clin Infect Dis 47(3):358\u2013363","journal-title":"Clin Infect Dis"}],"container-title":["European Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-014-2483-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00431-014-2483-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-014-2483-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-014-2483-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T01:29:20Z","timestamp":1659058160000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00431-014-2483-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,10]]},"references-count":20,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["2483"],"URL":"https:\/\/doi.org\/10.1007\/s00431-014-2483-3","relation":{},"ISSN":["0340-6199","1432-1076"],"issn-type":[{"value":"0340-6199","type":"print"},{"value":"1432-1076","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,10]]},"assertion":[{"value":"18 October 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 December 2014","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 December 2014","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 January 2015","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}