{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T07:53:40Z","timestamp":1789890820496,"version":"4.0.1"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2015,4,24]],"date-time":"2015-04-24T00:00:00Z","timestamp":1429833600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1007\/s00431-015-2540-6","type":"journal-article","created":{"date-parts":[[2015,4,23]],"date-time":"2015-04-23T01:19:07Z","timestamp":1429751947000},"page":"1387-1392","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Inherited metabolic disorders presenting as acute liver failure in newborns and young children: King\u2019s College Hospital experience"],"prefix":"10.1007","volume":"174","author":[{"given":"Robert","family":"Hegarty","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nedim","family":"Hadzic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Gissen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil","family":"Dhawan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,4,24]]},"reference":[{"key":"2540_CR1","doi-asserted-by":"crossref","first-page":"127","DOI":"10.4318\/tjg.2012.0319","volume":"23","author":"Z Bari\u015f","year":"2012","unstructured":"Bari\u015f Z, Saltik Tem\u0131zel IN, Uslu N, Usta Y, Dem\u0131r H, G\u00fcrakan F, Ozen H, Y\u00fcce A (2012) Acute liver failure in children: 20-year experience. Turk J Gastroenterol 23:127\u2013134","journal-title":"Turk J Gastroenterol"},{"key":"2540_CR2","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1055\/s-2007-1007248","volume":"16","author":"BR Bhaduri","year":"1996","unstructured":"Bhaduri BR, Mieli-Vergani G (1996) Fulminant hepatic failure: pediatric aspects. Semin Liver Dis 16:349\u2013355","journal-title":"Semin Liver Dis"},{"key":"2540_CR3","doi-asserted-by":"crossref","first-page":"S84","DOI":"10.1016\/j.ymgme.2010.02.012","volume":"1","author":"PM Campeau","year":"2010","unstructured":"Campeau PM, Pivalizza PJ, Miller G, McBride K, Karpen S, Goss J, Lee BH (2010) Early orthotopic liver transplantation in urea cycle defects: follow up of a developmental outcome study. Mol Genet Metab 1:S84\u2013S87","journal-title":"Mol Genet Metab"},{"key":"2540_CR4","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1111\/j.1399-3046.2004.00292.x","volume":"8","author":"A Dhawan","year":"2004","unstructured":"Dhawan A, Cheesman P, Mieli-Vergani G (2004) Approaches to acute liver failure in children. Pediatr Transplant 8:584\u2013588","journal-title":"Pediatr Transplant"},{"key":"2540_CR5","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.earlhumdev.2005.10.003","volume":"81","author":"A Dhawan","year":"2005","unstructured":"Dhawan A, Mieli-Vergani G (2005) Acute liver failure in neonates. Early Hum Dev 81:1005\u20131010","journal-title":"Early Hum Dev"},{"key":"2540_CR6","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1067\/mpd.2001.119989","volume":"139","author":"P Durand","year":"2001","unstructured":"Durand P, Debray D, Mandel R, Baujard C, Branchereau S, Gauthier F, Jacquemin E, Devictor D (2001) Acute liver failure in infancy: a 14-year experience of a pediatric liver transplantation center. J Pediatr 139:871\u2013876","journal-title":"J Pediatr"},{"key":"2540_CR7","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1086\/519219","volume":"81","author":"M He","year":"2007","unstructured":"He M, Rutledge SL, Kelly DR, Palmer CA, Murdoch G, Majumder N, Nicholls RD, Pei Z, Watkins PA, Vockley J (2007) A new genetic disorder in mitochondrial fatty acid beta-oxidation: ACAD9 deficiency. Am J Hum Genet 81:87\u2013103","journal-title":"Am J Hum Genet"},{"key":"2540_CR8","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1007\/s10545-012-9477-y","volume":"35","author":"P Jumbo-Lucioni","year":"2012","unstructured":"Jumbo-Lucioni P et al (2012) Diversity of approaches to classic galactosemia around the world: a comparison of diagnosis, intervention, and outcomes. J Inherit Metab Dis 35:1037\u20131049","journal-title":"J Inherit Metab Dis"},{"key":"2540_CR9","first-page":"62","volume":"56S2","author":"PJ McKiernan","year":"2013","unstructured":"McKiernan PJ, Ball S, Santra S, Gupte G, Sharif K, Hickman K, McFarland R, Fratter C, Poulton J, Rahman S, Taylor RW (2013) Incidence of mitochondrial disease in children presenting with acute liver failure under 2\u00a0years of age. J Pediatr Gastroenterol Nutr 56S2:62","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"2540_CR10","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.jpeds.2009.06.005","volume":"155","author":"MR Narkewicz","year":"2009","unstructured":"Narkewicz MR, Dell Olio D, Karpen SJ, Murray KF, Schwarz K, Yazigi N, Zhang S, Belle SH, Squires RH (2009) Pattern of diagnostic evaluation for the causes of pediatric acute liver failure: an opportunity for quality improvement. J Pediatr 155:801\u2013806","journal-title":"J Pediatr"},{"key":"2540_CR11","unstructured":"National Health Service Blood and Transplant (2013) Liver transplantation; selection criteria and recipient registration. [PDF] Available via http:\/\/www.odt.nhs.uk\/pdf\/liver_selection_policy.pdf [Accessed 12 September 2014]"},{"key":"2540_CR12","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1136\/adc.55.4.252","volume":"55","author":"HT Psacharopoulos","year":"1980","unstructured":"Psacharopoulos HT, Mowat AP, Davies M, Portmann B, Silk DB, Williams R (1980) Fulminant hepatic failure in childhood: an analysis of 31 cases. Arch Dis Child 55:252\u2013258","journal-title":"Arch Dis Child"},{"key":"2540_CR13","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s10545-013-9624-0","volume":"37","author":"CM R\u00fcegger","year":"2014","unstructured":"R\u00fcegger CM, Lindner M, Ballhausen D et al (2014) Cross-sectional observational study of 208 patients with non-classical urea cycle disorders. J Inherit Metab Dis 37:21\u201330","journal-title":"J Inherit Metab Dis"},{"key":"2540_CR14","doi-asserted-by":"crossref","first-page":"S50","DOI":"10.1007\/s00431-003-1352-2","volume":"162","author":"S Schweitzer-Krantz","year":"2003","unstructured":"Schweitzer-Krantz S (2003) Early diagnosis of inherited metabolic disorders towards improving outcome: the controversial issue of galactosemia. Eur J Pediatr 162:S50\u2013S53","journal-title":"Eur J Pediatr"},{"key":"2540_CR15","doi-asserted-by":"crossref","unstructured":"Shanmugam NP, Bansal S, Dhawan A (2012) Acute liver failure in children and adolescents. In: Dhawan A (ed) Concise pediatric and adolescent hepatology. Karger, Basel, Chapter 2","DOI":"10.1159\/000332064"},{"key":"2540_CR16","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1055\/s-2008-1073115","volume":"28","author":"RH Squires Jr","year":"2008","unstructured":"Squires RH Jr (2008) Acute liver failure in children. Semin Liver Dis 28:153\u2013166","journal-title":"Semin Liver Dis"},{"key":"2540_CR17","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.jpeds.2005.12.051","volume":"148","author":"RH Squires Jr","year":"2006","unstructured":"Squires RH Jr, Shneider BL, Bucuvalas J et al (2006) Acute liver failure in children: the first 348 patients in the pediatric acute liver failure study group. J Pediatr 148:652\u2013658","journal-title":"J Pediatr"},{"key":"2540_CR18","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/j.jpeds.2011.04.016","volume":"159","author":"SS Sundaram","year":"2011","unstructured":"Sundaram SS, Alonso EM, Narkewicz MR, Zhang S, Squires RH, Pediatric Acute Liver Failure Study Group (2011) Characterization and outcomes of young infants with acute liver failure. J Pediatr 159:813\u2013818","journal-title":"J Pediatr"}],"container-title":["European Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-015-2540-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00431-015-2540-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-015-2540-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T18:32:06Z","timestamp":1559068326000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00431-015-2540-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,24]]},"references-count":18,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["2540"],"URL":"https:\/\/doi.org\/10.1007\/s00431-015-2540-6","relation":{},"ISSN":["0340-6199","1432-1076"],"issn-type":[{"value":"0340-6199","type":"print"},{"value":"1432-1076","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,24]]}}}