{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T13:00:31Z","timestamp":1774530031789,"version":"3.50.1"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2017,3,16]],"date-time":"2017-03-16T00:00:00Z","timestamp":1489622400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"European Society of Pediatric Nephrology"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1007\/s00431-017-2891-2","type":"journal-article","created":{"date-parts":[[2017,3,16]],"date-time":"2017-03-16T17:45:05Z","timestamp":1489686305000},"page":"647-654","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Variability of diagnostic criteria and treatment of idiopathic nephrotic syndrome across European countries"],"prefix":"10.1007","volume":"176","author":[{"name":"On behalf of the ESPN Working Group on Idiopathic Nephrotic Syndrome","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5158-2915","authenticated-orcid":false,"given":"Georges","family":"Desch\u00eanes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Vivarelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Licia","family":"Peruzzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,3,16]]},"reference":[{"key":"2891_CR1","first-page":"203","volume":"45","author":"A Bagga","year":"2008","unstructured":"Bagga A, Ali U, Banerjee S, Kanitkar M, Phadke KD, Senguttuvan P, Sethi S, Shah M (2008) Management of steroid sensitive nephrotic syndrome: revised guidelines. Indian Pediatr 45:203\u2013214","journal-title":"Indian Pediatr"},{"key":"2891_CR2","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.nephro.2005.06.003","volume":"1","author":"E Berard","year":"2005","unstructured":"Berard E, Broyer M, Dehennault M, Dumas R, Eckart P, Fischbach M, Loirat C, Martinat L (2005) Corticosensitive nephrotic syndrome (or nephrosis) in children. Therapeutic guideline proposed by the Pediatric Society of Nephrology. Nephrol Ther 1:150\u2013156. doi: 10.1016\/j.nephro.2005.06.003","journal-title":"Nephrol. Ther"},{"key":"2891_CR3","first-page":"380","volume":"1","author":"J Brodehl","year":"1988","unstructured":"Brodehl J, Ehrich JHH (1988) Short versus standard prednisone therapy for initial treatment of idiopathic nephrotic syndrome in children. Arbeitsgemeinschaft fur Padiatrische Nephrologie. Lancet 1:380\u2013383","journal-title":"Lancet"},{"key":"2891_CR4","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1007\/s00467-013-2534-4","volume":"29","author":"G Cara-Fuentes","year":"2014","unstructured":"Cara-Fuentes G, Kairalla JA, Ishimoto T, Rivard C, Johnson RJ, Garin EH (2014) Rituximab in idiopathic nephrotic syndrome: does it make sense? Pediatr Nephrol 29:1313\u20131319. doi: 10.1007\/s00467-013-2534-4","journal-title":"Pediatr Nephrol"},{"key":"2891_CR5","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/BF01956754","volume":"152","author":"JH Ehrich","year":"1993","unstructured":"Ehrich JH, Brodehl J (1993) Long versus standard prednisone therapy for initial treatment of idiopathic nephrotic syndrome in children. Arbeitsgemeinschaft fur Padiatrische Nephrologie. Eur J Pediatr 152:357\u2013361","journal-title":"Eur J Pediatr"},{"key":"2891_CR6","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1007\/s00467-011-1851-8","volume":"26","author":"L Bakkali El","year":"2011","unstructured":"El Bakkali L, Rodrigues Pereira R, Kuik DJ, Ket JC, van Wijk JA (2011) Nephrotic syndrome in the Netherlands: a population-based cohort study and a review of the literature. Pediatr Nephrol 26:1241\u20131246. doi: 10.1007\/s00467-011-1851-8","journal-title":"Pediatr Nephrol"},{"key":"2891_CR7","doi-asserted-by":"publisher","first-page":"1970","DOI":"10.1093\/ndt\/gfr572","volume":"27","author":"J Gellermann","year":"2012","unstructured":"Gellermann J, Ehrich JH, Querfeld U (2012) Sequential maintenance therapy with cyclosporin A and mycophenolate mofetil for sustained remission of childhood steroid-resistant nephrotic syndrome. Nephrol Dial Transplant Off Pub Eur Dial Trans Assoc - Eur Renal Assoc 27:1970\u20131978. doi: 10.1093\/ndt\/gfr572","journal-title":"Nephrol. Dial. Transplant. Off Pub Eur Dial Trans Assoc - Eur Renal Assoc"},{"key":"2891_CR8","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1542\/peds.2008-1559","volume":"124","author":"DS Gipson","year":"2009","unstructured":"Gipson DS, Massengill SF, Yao L, Nagaraj S, Smoyer WE, Mahan JD, Wigfall D, Miles P, Powell L, Lin JJ, Trachtman H, Greenbaum LA (2009) Management of childhood onset nephrotic syndrome. Pediatrics 124:747\u2013757. doi: 10.1542\/peds.2008-1559","journal-title":"Pediatrics"},{"key":"2891_CR9","doi-asserted-by":"publisher","unstructured":"Hahn D, Hodson EM, Willis NS, Craig JC (2015) nephrotic syndrome in children. Cochrane Database Syst Rev (1):CD001533. doi: 10.1002\/14651858.CD001533.pub5","DOI":"10.1002\/14651858.CD001533.pub5"},{"key":"2891_CR10","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1007\/s00467-012-2393-4","volume":"28","author":"Y Hamasaki","year":"2013","unstructured":"Hamasaki Y, Yoshikawa N, Nakazato H, Sasaki S, Iijima K, Nakanishi K, Matsuyama T, Ishikura K, Ito S, Kaneko T, Honda M (2013) Prospective 5-year follow-up of cyclosporine treatment in children with steroid-resistant nephrosis. Pediatr Nephrol 28:765\u2013771. doi: 10.1007\/s00467-012-2393-4","journal-title":"Pediatr Nephrol"},{"key":"2891_CR11","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/S0272-6386(03)00346-9","volume":"41","author":"M Hiraoka","year":"2003","unstructured":"Hiraoka M, Tsukahara H, Matsubara K, Tsurusawa M, Takeda N, Haruki S, Hayashi S, Ohta K, Momoi T, Ohshima Y, Suganuma N, Mayumi M (2003) A randomized study of two long-course prednisolone regimens for nephrotic syndrome in children. Am J Kidney Dis 41:1155\u20131162","journal-title":"Am J Kidney Dis"},{"key":"2891_CR12","doi-asserted-by":"publisher","unstructured":"Hodson EM, Willis NS, Craig JC (2007) Corticosteroid therapy for nephrotic syndrome in children. Cochrane Database Syst Rev. doi: 10.1002\/14651858.CD001533.pub4","DOI":"10.1002\/14651858.CD001533.pub4"},{"key":"2891_CR13","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1016\/S0140-6736(14)60541-9","volume":"384","author":"K Iijima","year":"2014","unstructured":"Iijima K, Sako M, Nozu K, Mori R, Tuchida N, Kamei K, Miura K, Aya K, Nakanishi K, Ohtomo Y, Takahashi S, Tanaka R, Kaito H, Nakamura H, Ishikura K, Ito S, Ohashi Y (2014) Rituximab for childhood-onset, complicated, frequently relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome: a multicentre, double-blind, randomised, placebo-controlled trial. Lancet 384:1273\u20131281. doi: 10.1016\/S0140-6736(14)60541-9","journal-title":"Lancet"},{"key":"2891_CR14","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1038\/kisup.2012.13","volume":"2","author":"KDIGO","year":"2012","unstructured":"KDIGO (2012) KDIGO clinical practice guideline for glomerulonephritis. Kidney Int Suppl 2:143\u2013153. doi: 10.1038\/kisup.2012.13","journal-title":"Kidney Int. Suppl"},{"key":"2891_CR15","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1007\/s00467-012-2310-x","volume":"28","author":"RM Lombel","year":"2013","unstructured":"Lombel RM, Gipson DS, Hodson EM (2013) Treatment of steroid-sensitive nephrotic syndrome: new guidelines from KDIGO. Pediatr Nephrol 28:415\u2013426. doi: 10.1007\/s00467-012-2310-x","journal-title":"Pediatr Nephrol"},{"key":"2891_CR16","doi-asserted-by":"publisher","first-page":"2193","DOI":"10.1007\/s00467-009-1282-y","volume":"24","author":"N MacHardy","year":"2009","unstructured":"MacHardy N, Miles PV, Massengill SF, Smoyer WE, Mahan JD, Greenbaum L, Massie S, Yao L, Nagaraj S, Lin JJ, Wigfall D, Trachtman H, Hu Y, Gipson DS (2009) Management patterns of childhood-onset nephrotic syndrome. Pediatr Nephrol 24:2193\u20132201. doi: 10.1007\/s00467-009-1282-y","journal-title":"Pediatr Nephrol"},{"key":"2891_CR17","doi-asserted-by":"publisher","first-page":"1525","DOI":"10.1007\/s00467-009-1138-5","volume":"24","author":"D Mekahli","year":"2009","unstructured":"Mekahli D, Liutkus A, Ranchin B, Yu A, Bessenay L, Girardin E, Van Damme-Lombaerts R, Palcoux JB, Cachat F, Lavocat MP, Bourdat-Michel G, Nobili F, Cochat P (2009) Long-term outcome of idiopathic steroid-resistant nephrotic syndrome: a multicenter study. Pediatr Nephrol 24:1525\u20131532. doi: 10.1007\/s00467-009-1138-5","journal-title":"Pediatr Nephrol"},{"key":"2891_CR18","doi-asserted-by":"publisher","first-page":"756","DOI":"10.2215\/CJN.09010912","volume":"8","author":"K Nakanishi","year":"2013","unstructured":"Nakanishi K, Iijima K, Ishikura K, Hataya H, Nakazato H, Sasaki S, Honda M, Yoshikawa N (2013) Two-year outcome of the ISKDC regimen and frequent-relapsing risk in children with idiopathic nephrotic syndrome. Clin J Am Soc Nephrol CJASN 8:756\u2013762. doi: 10.2215\/CJN.09010912","journal-title":"Clin J Am Soc Nephrol CJASN"},{"key":"2891_CR19","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1053\/ajkd.2002.31400","volume":"39","author":"M Nakayama","year":"2002","unstructured":"Nakayama M, Katafuchi R, Yanase T, Ikeda K, Tanaka H, Fujimi S (2002) Steroid responsiveness and frequency of relapse in adult-onset minimal change nephrotic syndrome. Am J Kidney Dis 39:503\u2013512. doi: 10.1053\/ajkd.2002.31400","journal-title":"Am J Kidney Dis"},{"key":"2891_CR20","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1007\/s00467-014-2903-7","volume":"30","author":"A Pasini","year":"2015","unstructured":"Pasini A, Aceto G, Ammenti A, Ardissino G, Azzolina V, Bettinelli A, Cama E et al (2015) Best practice guidelines for idiopathic nephrotic syndrome: recommendations versus reality. Pediatr Nephrol 30:91\u2013101. doi: 10.1007\/s00467-014-2903-7","journal-title":"Pediatr Nephrol"},{"key":"2891_CR21","doi-asserted-by":"publisher","first-page":"2289","DOI":"10.1007\/s00467-013-2546-0","volume":"28","author":"S Samuel","year":"2013","unstructured":"Samuel S, Morgan CJ, Bitzan M, Mammen C, Dart AB, Manns BJ, Alexander RT, Erickson RL, Grisaru S, Wade AW, Blydt-Hansen T, Feber J, Arora S, Licht C, Zappitelli M (2013) Substantial practice variation exists in the management of childhood nephrotic syndrome. Pediatr Nephrol 28:2289\u20132298. doi: 10.1007\/s00467-013-2546-0","journal-title":"Pediatr Nephrol"},{"key":"2891_CR22","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1093\/ndt\/gfr405","volume":"27","author":"AL Sellier-Leclerc","year":"2012","unstructured":"Sellier-Leclerc AL, Baudouin V, Kwon T, Macher MA, Guerin V, Lapillonne H, Deschenes G, Ulinski T (2012) Rituximab in steroid-dependent idiopathic nephrotic syndrome in childhood\u2014follow-up after CD19 recovery. Nephrol Dial, Trans Off Pub Eur Dial Trans Assoc - Eur Renal Assoc 27:1083\u20131089. doi: 10.1093\/ndt\/gfr405","journal-title":"Nephrol Dial, Trans Off Pub Eur Dial Trans Assoc - Eur Renal Assoc"},{"key":"2891_CR23","doi-asserted-by":"publisher","first-page":"1875","DOI":"10.1007\/s00467-013-2485-9","volume":"28","author":"AL Sellier-Leclerc","year":"2013","unstructured":"Sellier-Leclerc AL, Belli E, Guerin V, Dorfmuller P, Deschenes G (2013) Fulminant viral myocarditis after rituximab therapy in pediatric nephrotic syndrome. Pediatr Nephrol 28:1875\u20131879. doi: 10.1007\/s00467-013-2485-9","journal-title":"Pediatr Nephrol"},{"key":"2891_CR24","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1038\/ki.2014.240","volume":"87","author":"A Sinha","year":"2015","unstructured":"Sinha A, Saha A, Kumar M, Sharma S, Afzal K, Mehta A, Kalaivani M, Hari P, Bagga A (2015) Extending initial prednisolone treatment in a randomized control trial from 3 to 6 months did not significantly influence the course of illness in children with steroid-sensitive nephrotic syndrome. Kidney Int 87:217\u2013224. doi: 10.1038\/ki.2014.240","journal-title":"Kidney Int"},{"key":"2891_CR25","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1681\/ASN.V85769","volume":"8","author":"P Tarshish","year":"1997","unstructured":"Tarshish P, Tobin JN, Bernstein J, Edelmann CM Jr (1997) Prognostic significance of the early course of minimal change nephrotic syndrome: report of the International Study of Kidney Disease in Children. Clin J Am Soc Nephrol JASN 8:769\u2013776","journal-title":"Clin J Am Soc Nephrol JASN"},{"key":"2891_CR26","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/ki.2014.260","volume":"87","author":"N Yoshikawa","year":"2015","unstructured":"Yoshikawa N, Nakanishi K, Sako M, Oba MS, Mori R, Ota E, Ishikura K, Hataya H, Honda M, Ito S, Shima Y, Kaito H, Nozu K, Nakamura H, Igarashi T, Ohashi Y, Iijima K (2015) A multicenter randomized trial indicates initial prednisolone treatment for childhood nephrotic syndrome for two months is not inferior to six-month treatment. Kidney Int 87:225\u2013232. doi: 10.1038\/ki.2014.260","journal-title":"Kidney Int"},{"key":"2891_CR27","doi-asserted-by":"publisher","first-page":"191","DOI":"10.5935\/0101-2800.20130031","volume":"35","author":"A Zagury","year":"2013","unstructured":"Zagury A, Oliveira AL, Montalvao JA, Novaes RH, Sa VM, Moraes CA, Tavares Mde S (2013) Steroid-resistant idiopathic nephrotic syndrome in children: long-term follow-up and risk factors for end-stage renal disease. Jornal brasileiro de nefrologia: \u2032orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia 35:191\u2013199. doi: 10.5935\/0101-2800.20130031","journal-title":"Jornal brasileiro de nefrologia: \u2032orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia"}],"container-title":["European Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00431-017-2891-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-017-2891-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-017-2891-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T11:44:10Z","timestamp":1658835850000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00431-017-2891-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,16]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["2891"],"URL":"https:\/\/doi.org\/10.1007\/s00431-017-2891-2","relation":{},"ISSN":["0340-6199","1432-1076"],"issn-type":[{"value":"0340-6199","type":"print"},{"value":"1432-1076","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,16]]}}}