{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:10:21Z","timestamp":1740107421010,"version":"3.37.3"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2020,3,5]],"date-time":"2020-03-05T00:00:00Z","timestamp":1583366400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,3,5]],"date-time":"2020-03-05T00:00:00Z","timestamp":1583366400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1007\/s00431-020-03607-6","type":"journal-article","created":{"date-parts":[[2020,3,5]],"date-time":"2020-03-05T21:02:33Z","timestamp":1583442153000},"page":"1353-1360","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Cancer treatment in disabled children"],"prefix":"10.1007","volume":"179","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1875-9563","authenticated-orcid":false,"given":"Cristina","family":"Meazza","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Schiavello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veronica","family":"Biassoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Podda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Barteselli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Barretta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanna","family":"Gattuso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Terenziani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Ferrari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filippo","family":"Spreafico","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Luksch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michela","family":"Casanova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Chiaravalli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Puma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Bergamaschi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maura","family":"Massimino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,3,5]]},"reference":[{"issue":"10","key":"3607_CR1","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1158\/1055-9965.1552.13.10","volume":"13","author":"J Ross","year":"2004","unstructured":"Ross J, Olshan A (2004) Pediatric Cancer in the United States: th Children's oncology group epidemiology research program. Cancer Epidemiol Biomark Prev 13(10):1552\u20131554","journal-title":"Cancer Epidemiol Biomark Prev"},{"key":"3607_CR2","doi-asserted-by":"publisher","first-page":"1939","DOI":"10.1002\/cncr.20985","volume":"103","author":"MM Agha","year":"2005","unstructured":"Agha MM, Williams JI, Marrett L, To T, Zipursky A, Dodds L (2005) Congenital abnormalities and childhood cancer: a cohort record-linkage study. Cancer 103:1939\u20131948. https:\/\/doi.org\/10.1002\/cncr.20985","journal-title":"Cancer"},{"issue":"5","key":"3607_CR3","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1002\/pbc.21682","volume":"51","author":"J Rankin","year":"2008","unstructured":"Rankin J, Silf KA, Pearce MS, Parker L, Platt MW (2008) Congenital anomaly and childhood cancer: a population-based, record linkage study. Pediatr Blood Cancer 51(5):608\u2013612. https:\/\/doi.org\/10.1002\/pbc.21682","journal-title":"Pediatr Blood Cancer"},{"issue":"1","key":"3607_CR4","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1001\/jama.2007.66","volume":"299","author":"JHM Merks","year":"2008","unstructured":"Merks JHM, \u00d6zgen HM, Koster J, Zwinderman AH, Caron HN, Hennekam RCM (2008) Prevalence and patterns of morphological abnormalities in patients with childhood cancer. JAMA - J Am Med Assoc 299(1):61\u201369. https:\/\/doi.org\/10.1001\/jama.2007.66","journal-title":"JAMA - J Am Med Assoc"},{"key":"3607_CR5","doi-asserted-by":"publisher","unstructured":"Pisani CP, Buzzoni C, Crocetti E et al (2012) AIRTUM working group \u2013 AIEOP working group I tumori Dei bambini e degli adolescenti Cancer in children and adolescents AIRTUM working group and AIEOP working group. https:\/\/doi.org\/10.2337\/dc12-s011","DOI":"10.2337\/dc12-s011"},{"key":"3607_CR6","doi-asserted-by":"publisher","unstructured":"(2001) Healthy ageing - adults with intellectual disabilities: summative report. J Appl Res Intellect Disabil. https:\/\/doi.org\/10.1046\/j.1468-3148.2001.00071.x","DOI":"10.1046\/j.1468-3148.2001.00071.x"},{"issue":"2","key":"3607_CR7","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1111\/j.1469-8749.1997.tb07395.x","volume":"39","author":"N Roeleveld","year":"1997","unstructured":"Roeleveld N, Zielhuis GA (1997) The prevalence of mental retardation: a critical review of recent literature. Dev Med Child Neurol 39(2):125\u2013132. https:\/\/doi.org\/10.1111\/j.1469-8749.1997.tb07395.x","journal-title":"Dev Med Child Neurol"},{"issue":"3","key":"3607_CR8","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1093\/oxfordjournals.aje.a009448","volume":"147","author":"MS Durkin","year":"1998","unstructured":"Durkin MS, Hasan ZM, Hasan KZ (1998) Prevalence and correlates of mental retardation among children in Karachi, Pakistan. Am J Epidemiol 147(3):281\u2013288. https:\/\/doi.org\/10.1093\/oxfordjournals.aje.a009448","journal-title":"Am J Epidemiol"},{"issue":"10","key":"3607_CR9","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1007\/s10552-004-1256-0","volume":"15","author":"SG Sullivan","year":"2004","unstructured":"Sullivan SG, Hussain R, Threlfall T, Bittles AH (2004) The incidence of cancer in people with intellectual disabilities. Cancer Causes Control 15(10):1021\u20131025. https:\/\/doi.org\/10.1007\/s10552-004-1256-0","journal-title":"Cancer Causes Control"},{"issue":"Pt4","key":"3607_CR10","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1046\/j.1365-2788.2001.00322.x","volume":"45","author":"K Patja","year":"2001","unstructured":"Patja K, Eero P, Iivanainen M (2001) Cancer incidence among people with intellectual disability. J Intellect Disabil Res 45(Pt4):300\u2013307. https:\/\/doi.org\/10.1046\/j.1365-2788.2001.00322.x","journal-title":"J Intellect Disabil Res"},{"issue":"3","key":"3607_CR11","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1002\/(SICI)1096-8628(19980707)78:3<207::AID-AJMG1>3.0.CO;2-M","volume":"78","author":"D Satg\u00e9","year":"1998","unstructured":"Satg\u00e9 D, Sommelet D, Geneix A, Nishi M, Malet P, Vekemans M (1998) A tumor profile in down syndrome. Am J Med Genet 78(3):207\u2013216","journal-title":"Am J Med Genet"},{"issue":"6","key":"3607_CR12","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1001\/archinte.163.6.705","volume":"163","author":"DA Hill","year":"2003","unstructured":"Hill DA, Gridley G, Cnattingius S et al (2003) Mortality and cancer incidence among individuals with down syndrome. Arch Intern Med 163(6):705\u2013711. https:\/\/doi.org\/10.1001\/archinte.163.6.705","journal-title":"Arch Intern Med"},{"issue":"9199","key":"3607_CR13","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/S0140-6736(99)05264-2","volume":"355","author":"H Hasle","year":"2000","unstructured":"Hasle H, Haunstrup Clemmensen I, Mikkelsen M (2000) Risks of leukaemia and solid tumours in individuals with Down\u2019s syndrome. Lancet 355(9199):165\u2013169. https:\/\/doi.org\/10.1016\/S0140-6736(99)05264-2","journal-title":"Lancet"},{"issue":"9","key":"3607_CR14","doi-asserted-by":"publisher","first-page":"1633","DOI":"10.1093\/hmg\/3.9.1633","volume":"3","author":"K Pritchard-jones","year":"1994","unstructured":"Pritchard-jones K, Renshaw J, King-underwood L (1994) The Wilms tumour (WT1) gene is mutated in a secondary leukaemia in a WAGR patient. Hum Mol Genet 3(9):1633\u20131637. https:\/\/doi.org\/10.1093\/hmg\/3.9.1633","journal-title":"Hum Mol Genet"},{"issue":"10","key":"3607_CR15","doi-asserted-by":"publisher","first-page":"2208","DOI":"10.1002\/(SICI)1097-0142(19981115)83:10<2208::AID-CNCR21>3.0.CO;2-K","volume":"83","author":"T Al-Saleem","year":"1998","unstructured":"Al-Saleem T, Wessner LL, Scheithauer BW et al (1998) Malignant tumors of the kidney, brain, and soft tissues in children and young adults with the tuberous sclerosis complex. Cancer 83(10):2208\u20132216. https:\/\/doi.org\/10.1002\/(SICI)1097-0142(19981115)83:10<2208::AID-CNCR21>3.0.CO;2-K","journal-title":"Cancer"},{"issue":"9368","key":"3607_CR16","doi-asserted-by":"publisher","first-page":"1552","DOI":"10.1016\/S0140-6736(03)13166-2","volume":"361","author":"RM Reynolds","year":"2003","unstructured":"Reynolds RM, Browning GGP, Nawroz I, Campbell IW (2003) Von Recklinghausen\u2019s neurofibromatosis: Neurofibromatosis type 1. Lancet 361(9368):1552\u20131554","journal-title":"Lancet"},{"key":"3607_CR17","doi-asserted-by":"publisher","first-page":"1392","DOI":"10.1038\/bjc.2015.75","volume":"112","author":"CP Kratz","year":"2015","unstructured":"Kratz CP, Franke L, Peters H, Kohlschmidt N, Kazmierczak B, Finckh U et al (2015) Cancer spectrum and frequency among childrten with Noonan, Costello and cardio-facio-cutaneous syndromes. Br J Cancer 112:1392\u20131397","journal-title":"Br J Cancer"},{"key":"3607_CR18","first-page":"195.201","volume":"170A","author":"GD McWilliams","year":"2016","unstructured":"McWilliams GD, SantaKruz K, Hart B, Clericuzio C (2016) Occurance of DNET and other brain tumors in Noonan syndrome warrant caution growth hormone therapy. Am J Med Genet Part A 170A:195.201","journal-title":"Am J Med Genet Part A"},{"key":"3607_CR19","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1038\/ejhg.2011.37","volume":"19","author":"MC Jongmans","year":"2011","unstructured":"Jongmans MC, van der Burget I, Hoogerbrugge PM, Noordan K, Yntema HG, Nillesen WM et al (2011) Cancer risk in patinets with Noonan syndrome carrying a PTPN11 mutation. Eur J Hum Genet 19:870\u2013874","journal-title":"Eur J Hum Genet"},{"key":"3607_CR20","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1002\/ajmg.c.30300","volume":"157C","author":"CP Kraz","year":"2011","unstructured":"Kraz CP, Rapisuwon S, Reed H, Hasle H, Rosenberg PS (2011) Cancer in Noonan, Costello, cardiofaciocutaneous and LEOPARD syndromes. Am J Med Genet C Semin Med Genet 157C:83\u201389","journal-title":"Am J Med Genet C Semin Med Genet"},{"key":"3607_CR21","doi-asserted-by":"publisher","unstructured":"Villani A, Greer MC, Kalish JM, Nakagawara A, Nathanson KL, Pajtler KW, Pfister SM, Walsh MF, Wasserman JD, Zelley K, Kratz CP (2017) Recommendations for Cancer surveillance in individuals with RASopathies and other rare genetic conditions with increased Cancer risk. Clin Cancer Res 23(12):e83\u2013e90. https:\/\/doi.org\/10.1158\/1078-0432.CCR-17-0631","DOI":"10.1158\/1078-0432.CCR-17-0631"}],"container-title":["European Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-020-03607-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00431-020-03607-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-020-03607-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T19:13:29Z","timestamp":1666034009000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00431-020-03607-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,5]]},"references-count":21,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["3607"],"URL":"https:\/\/doi.org\/10.1007\/s00431-020-03607-6","relation":{},"ISSN":["0340-6199","1432-1076"],"issn-type":[{"type":"print","value":"0340-6199"},{"type":"electronic","value":"1432-1076"}],"subject":[],"published":{"date-parts":[[2020,3,5]]},"assertion":[{"value":"16 January 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 February 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 February 2020","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 March 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical statements"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}