{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T04:01:48Z","timestamp":1790654508701,"version":"4.1.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T00:00:00Z","timestamp":1590537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T00:00:00Z","timestamp":1590537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1007\/s00431-020-03682-9","type":"journal-article","created":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T05:02:47Z","timestamp":1590555767000},"page":"1287-1293","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":75,"title":["Minimally invasive surfactant therapy versus InSurE in preterm neonates of 28 to 34 weeks with respiratory distress syndrome on non-invasive positive pressure ventilation\u2014a randomized controlled trial"],"prefix":"10.1007","volume":"179","author":[{"given":"Bhupendra Kumar","family":"Gupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anindya Kumar","family":"Saha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suchandra","family":"Mukherjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bijan","family":"Saha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,5,27]]},"reference":[{"key":"3682_CR1","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1159\/000480066","volume":"113","author":"PA Dargaville","year":"2016","unstructured":"Dargaville PA, Ali SKM, Jackson HD, Williams C, De Paoli AG (2016) Impact of minimally invasive surfactant therapy in preterm infants at 29\u201332 weeks gestation. Neonatology 113:7\u201314","journal-title":"Neonatology"},{"issue":"16","key":"3682_CR2","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1056\/NEJM199410203311603","volume":"331","author":"H Verder","year":"1994","unstructured":"Verder H, Robertson B, Greisen G et al (1994) Surfactant therapy and nasal continuous positive pressure for newborn with respiratory distress syndrome. N Engl J Med 331(16):1051\u20131055","journal-title":"N Engl J Med"},{"issue":"4","key":"3682_CR3","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1111\/j.1460-9592.2006.02126.x","volume":"17","author":"A Kribs","year":"2007","unstructured":"Kribs A, Pillekamp F, Hunseler C, Vierzig A, Roth B (2007) Early administration of surfactant in spontaneous breathing with nCPAP: feasibility and outcome in extremely premature infants (postmenstrual age \u2264 27 weeks). Paediatr Anaesth 17(4):364\u2013369","journal-title":"Paediatr Anaesth"},{"key":"3682_CR4","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1056\/NEJMoa072788","volume":"358","author":"CJ Morley","year":"2008","unstructured":"Morley CJ, Davis PG, Doyle LW, Brion LP, Hascoet JM, Carlin JB (2008) Nasal CPAP or intubation at birth for very preterm infants. N Engl J Med 358:700\u2013708","journal-title":"N Engl J Med"},{"key":"3682_CR5","doi-asserted-by":"publisher","first-page":"1970","DOI":"10.1056\/NEJMoa0911783","volume":"362","author":"NN Finer","year":"2010","unstructured":"Finer NN, Carlo WA, Walsh MC et al (2010) Early CPAP versus surfactant in extremely preterm infants. N Engl J Med 362:1970\u20131979","journal-title":"N Engl J Med"},{"key":"3682_CR6","doi-asserted-by":"publisher","first-page":"e1069","DOI":"10.1542\/peds.2010-3848","volume":"128","author":"MS Dunn","year":"2011","unstructured":"Dunn MS, Kaempf J, de Klerk A et al (2011) Randomised trial comparing 3 approaches to the initial respiratory management of preterm neonates. Pediatrics 128:e1069\u2013e1076","journal-title":"Pediatrics"},{"issue":"11","key":"3682_CR7","first-page":"177","volume":"116","author":"J Behnke","year":"2019","unstructured":"Behnke J, Lemyre B, Czernik C, Zimmer KP, Ehrhardt H, Waitz M (2019) Non-invasive ventilation in neonatology. DeutschesArztebla International 116(11):177\u2013183","journal-title":"DeutschesArztebla International"},{"key":"3682_CR8","first-page":"CD003212","volume":"2","author":"B Lemyre","year":"2016","unstructured":"Lemyre B, Laughon M, Bose C, Davis PG (2016) Early nasal intermittent positive pressure ventilation (NIPPV) versus early nasal continuous positive pressure(nCPAP) for preterm infants. Cochrane Database Syst Rev 2:CD003212","journal-title":"Cochrane Database Syst Rev"},{"key":"3682_CR9","first-page":"1412","volume":"98","author":"MSS Kishore","year":"2009","unstructured":"Kishore MSS, Dutta S, Praveen K (2009) Early nasal intermittent positive pressure ventilation versus nasal continuous positive airway pressure for respiratory distress syndrome. Actapaediatrica 98:1412\u20131415","journal-title":"Actapaediatrica"},{"key":"3682_CR10","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1002\/ppul.22883","volume":"49","author":"Y Shi","year":"2013","unstructured":"Shi Y, Tang S, Zhao J, Shen J (2013) A prospective ,randomised, controlled study of NIPPV versus nCPAP in preterm and term infants with respiratory distress syndrome. Pediatr Pulmonol 49:673\u2013678","journal-title":"Pediatr Pulmonol"},{"key":"3682_CR11","doi-asserted-by":"publisher","first-page":"F122","DOI":"10.1136\/archdischild-2011-301314","volume":"98","author":"PA Dargaville","year":"2013","unstructured":"Dargaville PA, Aiyappan A, De Paoli AG, Kuschel CA et al (2013) Minimally invasive surfactant therapy in preterm infants on continuous positive airway pressure. Arch Dis Child Fetal Neonatal 98:F122\u2013F126","journal-title":"Arch Dis Child Fetal Neonatal"},{"issue":"8","key":"3682_CR12","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1007\/s00431-009-0983-3","volume":"168","author":"A Sehgal","year":"2009","unstructured":"Sehgal A, McNamara PJ (2009) Does echocardiography facilitate determination of hemodynamically significance attributable to the ductus arteriosus ? Eur J Pediatr 168(8):907\u2013914","journal-title":"Eur J Pediatr"},{"key":"3682_CR13","doi-asserted-by":"crossref","unstructured":"Papile LA, Burstein J,Brustein R, Koffler H. (1978) Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500gm.pediatrics 92:529-34","DOI":"10.1016\/S0022-3476(78)80282-0"},{"key":"3682_CR14","doi-asserted-by":"crossref","unstructured":"Jobe AH, Bancalari E (2001) Bronchopulmonary dysplasia: NICHD\/NHLBI\/ORD workshop summary. Am J Respir Crit Care Med.163:1723-9","DOI":"10.1164\/ajrccm.163.7.2011060"},{"key":"3682_CR15","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1056\/NEJMoa1214533","volume":"369","author":"H Kripalani","year":"2013","unstructured":"Kripalani H, Miller D, Lemyre B, Yoder BA, Chiu A, Roberts RS (2013) A trial comparing noninvasive ventilation strategies in preterm infants. N Engl J Med 369:611\u2013620","journal-title":"N Engl J Med"},{"issue":"2","key":"3682_CR16","doi-asserted-by":"publisher","first-page":"e502","DOI":"10.1542\/peds.2012-0603","volume":"131","author":"HG Kanmaz","year":"2013","unstructured":"Kanmaz HG, Erdeve O, Canpolat FE, Mutlu B, Dilmen U (2013) Surfactant administration via thin catheter during spontaneous breathing: randomised controlled trial. Pediatrics 131(2):e502\u2013e509","journal-title":"Pediatrics"},{"key":"3682_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/2333794X17696683","volume":"4","author":"CSM Lau","year":"2017","unstructured":"Lau CSM, Chamberlain RS, Sun S (2017) Less invasive surfactant administration reduces the need for mechanical ventilation in preterm infants: a meta-analysis. Global Pediatric Health 4:1\u20139","journal-title":"Global Pediatric Health"},{"key":"3682_CR18","doi-asserted-by":"publisher","first-page":"F17","DOI":"10.1136\/archdischild-2015-310299","volume":"102","author":"JC Aldana-Aguirre","year":"2017","unstructured":"Aldana-Aguirre JC, Pinto M, Featherstone RM, Kumar M (2017) Less invasive surfactant administration versus intubation for surfactant delivery in preterm infants with respiratory distress syndrome : a systematic review and meta analysis. Arch Dis Child Fetal Neonatal Ed 102:F17\u2013F23","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"3682_CR19","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1378\/chest.121.4.1149","volume":"121","author":"M Antonelli","year":"2002","unstructured":"Antonelli M, Conti G, Rocco M, Arcangeli A, Cavaliere F, Proietti R, Meduri GU (2002) Noninvasive positive-pressure ventilation vs conventional oxygen supplementation in hypoxemic patients undergoing diagnostic bronchoscopy. Chest 121:1149\u20131154","journal-title":"Chest"},{"key":"3682_CR20","doi-asserted-by":"publisher","first-page":"f323","DOI":"10.1136\/archdischild-2015-308204","volume":"101","author":"MY Oncel","year":"2016","unstructured":"Oncel MY, Arayici S, Uras N, Alyamac-Dizdar E, Sari FN, Karahan S, Canpolat FE, Oguz SS, Dilmen U (2016) Nasal continuous positive airway pressure versus nasal intermittent positive-pressure ventilation within the minimally invasive surfactant therapy approach inpreterm infants: a randomised controlled trial. Arch Dis Child Fetal Neonatal Ed 101:f323\u2013f328","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"3","key":"3682_CR21","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1038\/s41372-017-0009-3","volume":"38","author":"G Jourdain","year":"2018","unstructured":"Jourdain G, De Tersant M, Dell'Orto V, Conti G, De Luca D (2018) Continuous positive airway pressure delivery during less invasive surfactant administration: a physiologic study. J Perinatol 38(3):271\u2013277","journal-title":"J Perinatol"},{"key":"3682_CR22","doi-asserted-by":"publisher","first-page":"1627","DOI":"10.1016\/S0140-6736(11)60986-0","volume":"378","author":"W G\u00f6pel","year":"2011","unstructured":"G\u00f6pel W, Kribs A, Ziegler A, Laux R, Hoehn T, Wieg C, Siegel J, Avenarius S, von der Wense A, Vochem M, Groneck P, Weller U, M\u00f6ller J, H\u00e4rtel C, Haller S, Roth B, Herting E, German Neonatal Network (2011) Avoidance of mechanical ventilation by surfactant treatment of spontaneously breathing preterm infants (AMV): an open-label, randomised, controlled trial. Lancet 378:1627\u20131634","journal-title":"Lancet"},{"issue":"4","key":"3682_CR23","first-page":"e 60724","volume":"8","author":"Z Mosayebi","year":"2017","unstructured":"Mosayebi Z, Kadivar M, Derakhsh NT, Nariman S, Marashi SM, Farsi Z (2017) A randomized trial comparing surfactant administration using InSurE technique and the minimally invasive surfactant therapy in preterm infants (28 to 34 Weeks of Gestation) with Respiratory Distress Syndrome. J Compr Ped 8(4):e 60724","journal-title":"J Compr Ped"},{"key":"3682_CR24","doi-asserted-by":"publisher","first-page":"e229","DOI":"10.1111\/apa.12611","volume":"103","author":"M Aguar","year":"2014","unstructured":"Aguar M, Cernada M, Brugada M, Gimeno A, Gutierrez A, Vento M (2014) Minimally invasive surfactant therapy with a gastric tube is as effective as the intubation, surfactant, and extubation technique in preterm babies. Acta Paediatr 103:e229\u2013e233","journal-title":"Acta Paediatr"},{"key":"3682_CR25","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/S2352-4642(19)30405-5","volume":"4","author":"D De Luca","year":"2020","unstructured":"De Luca D, Aguilera SS, Centorrino R, Fortas F, Yousef N, Carnielli VP (2020) Less invasive surfactant administration: a word of caution. Lancet Child Adolesc Health 4:331\u2013340. https:\/\/doi.org\/10.1016\/S2352-4642(19)30405-5","journal-title":"Lancet Child Adolesc Health"},{"issue":"2","key":"3682_CR26","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1038\/pr.2014.66","volume":"76","author":"HJ Niemarkt","year":"2014","unstructured":"Niemarkt HJ, Kuypers E, Jellema R, Ophelders D, H\u00fctten M, Nikiforou M, Kribs A, Kramer BW (2014) Effects of less-invasive surfactant administration on oxygenation, pulmonary surfactant distribution, and lung compliance in spontaneously breathing preterm lambs. Pediatr Res 76(2):166\u2013170","journal-title":"Pediatr Res"},{"issue":"8","key":"3682_CR27","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1002\/ppul.24358","volume":"54","author":"R Centorrino","year":"2019","unstructured":"Centorrino R, Dell'Orto V, Gitto E, Conti G, De Luca D (2019) Mechanics of nasal mask-delivered HFOV in neonates: a physiologic study. Pediatr Pulmonol 54(8):1304\u20131310","journal-title":"Pediatr Pulmonol"},{"issue":"3","key":"3682_CR28","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1007\/s00134-010-2091-2","volume":"37","author":"PE Cogo","year":"2011","unstructured":"Cogo PE, Facco M, Simonato M, De Luca D, De Terlizi F, Rizzotti U, Verlato G, Bellagamba MP, Carnielli VP (2011) Pharmacokinetics and clinical predictors of surfactant redosing in respiratory distress syndrome. Intensive Care Med 37(3):510\u2013517","journal-title":"Intensive Care Med"},{"key":"3682_CR29","first-page":"109","volume":"10","author":"DJ Davis","year":"2005","unstructured":"Davis DJ, Barrington KJ (2005) Recommendations for neonatal surfactant therapy. Paediatr Child Health 10:109\u2013116","journal-title":"Paediatr Child Health"},{"key":"3682_CR30","doi-asserted-by":"crossref","unstructured":"Figueras-Aloy J, Quero J, Carbonell-Estrany X, et al.(2001) Early administration of the second dose of surfactant (beractant) in the treatment of severe hyaline membrane disease. Acta Paediatr 0.90:296-301.","DOI":"10.1111\/j.1651-2227.2001.tb00308.x"}],"container-title":["European Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-020-03682-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00431-020-03682-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-020-03682-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T05:44:33Z","timestamp":1744177473000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00431-020-03682-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,27]]},"references-count":30,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["3682"],"URL":"https:\/\/doi.org\/10.1007\/s00431-020-03682-9","relation":{},"ISSN":["0340-6199","1432-1076"],"issn-type":[{"value":"0340-6199","type":"print"},{"value":"1432-1076","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,27]]},"assertion":[{"value":"24 March 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 May 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 May 2020","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 May 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The ethical approval for the study was taken from the Institutional Ethics Committee, Institute of Post Graduate Medical Education and Research,, Kolkata, India(Inst\/IEC\/2018\/393, dated 28.04.2019).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from the legal guardian of all included participants.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent to participate"}}]}}