{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:55:50Z","timestamp":1787504150426,"version":"build-2736575974"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2021,3,5]],"date-time":"2021-03-05T00:00:00Z","timestamp":1614902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,3,5]],"date-time":"2021-03-05T00:00:00Z","timestamp":1614902400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Clinical Research Institute HUCH"},{"DOI":"10.13039\/501100005744","name":"Lastentautien Tutkimuss\u00e4\u00e4ti\u00f6","doi-asserted-by":"crossref","award":["200156"],"award-info":[{"award-number":["200156"]}],"id":[{"id":"10.13039\/501100005744","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004756","name":"Emil Aaltosen S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","award":["200190 K"],"award-info":[{"award-number":["200190 K"]}],"id":[{"id":"10.13039\/501100004756","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Congenital abdominal wall defects, namely, gastroschisis and omphalocele, are rare congenital malformations with significant morbidity. The long-term burden of these anomalies to families and health care providers has not previously been assessed. We aimed to determine the need for hospital admissions and the requirement for surgery after initial admission at birth. For our analyses, we identified all infants with either gastroschisis (\n                    <jats:italic>n<\/jats:italic>\n                    =178) or omphalocele (\n                    <jats:italic>n<\/jats:italic>\n                    =150) born between Jan 1, 1998, and Dec 31, 2014, in the Register of Congenital Malformations. The data on all hospital admissions and operations performed were acquired from the Finnish Hospital Discharge Register between Jan 1, 1998, and Dec 31, 2015, and compared to data on the whole Finnish pediatric population (0.9\u2009million) live born 1993\u22122008. Patients with gastroschisis and particularly those with omphalocele required hospital admissions 1.8 to 5.7 times more than the general pediatric population (\n                    <jats:italic>p<\/jats:italic>\n                    &lt;0.0001). Surgical interventions were more common among omphalocele than gastroschisis patients (\n                    <jats:italic>p<\/jats:italic>\n                    =0.013). At the mean follow-up of 8.9 (range 1.0\u201318.0) years, 29% (51\/178) of gastroschisis and 30% (45\/150) of omphalocele patients required further abdominal surgery after discharge from the neonatal admission.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusion<\/jats:italic>\n                    : Patients with gastroschisis and especially those with omphalocele, are significantly more likely than the general pediatric population to require hospital care. Nevertheless, almost half of the patients can be treated without further surgery, and redo abdominal surgery is only required in a third of these children.\n                    <jats:table-wrap>\n                      <jats:table>\n                        <jats:tbody>\n                          <jats:tr>\n                            <jats:td colspan=\"2\">\n                              <jats:bold>What is Known:<\/jats:bold>\n                              \u2022\n                              <jats:italic>Gastroschisis and omphalocele are congenital malformations with significant morbidity<\/jats:italic>\n                              \u2022\n                              <jats:italic>There are no reports on the long-term need for hospital admissions and surgery in these children<\/jats:italic>\n                              <jats:bold>What is New:<\/jats:bold>\n                              \u2022\n                              <jats:italic>Patients with abdominal wall defects are significantly more likely than the general pediatric population to require hospital care<\/jats:italic>\n                              \u2022\n                              <jats:italic>Almost half of the patients can be treated without further surgery, and abdominal redo operations are only required in a third of these children<\/jats:italic>\n                            <\/jats:td>\n                          <\/jats:tr>\n                        <\/jats:tbody>\n                      <\/jats:table>\n                    <\/jats:table-wrap>\n                  <\/jats:p>","DOI":"10.1007\/s00431-021-04005-2","type":"journal-article","created":{"date-parts":[[2021,3,5]],"date-time":"2021-03-05T00:02:24Z","timestamp":1614902544000},"page":"2193-2198","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Long-term hospital admissions and surgical treatment of children with congenital abdominal wall defects: a population-based study"],"prefix":"10.1007","volume":"180","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9114-2204","authenticated-orcid":false,"given":"Arimatias","family":"Raitio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Syv\u00e4nen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asta","family":"Tauriainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Hyv\u00e4rinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulla","family":"Sankilampi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mika","family":"Gissler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilkka","family":"Helenius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,5]]},"reference":[{"key":"4005_CR1","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1055\/s-0039-3401797","volume":"30","author":"A Raitio","year":"2020","unstructured":"Raitio A, Lahtinen A, Syv\u00e4nen J, Kemppainen T, L\u00f6yttyniemi E, Gissler M, Hyv\u00e4rinen A, Helenius I (2020) Gastroschisis in Finland 1993 to 2014-increasing prevalence, high rates of abortion, and survival: a population-based study. Eur J Pediatr Surg 30:536\u2013540. https:\/\/doi.org\/10.1055\/s-0039-3401797","journal-title":"Eur J Pediatr Surg"},{"key":"4005_CR2","doi-asserted-by":"publisher","unstructured":"Raitio A, Tauriainen A, Syv\u00e4nen J, Kemppainen T, L\u00f6yttyniemi E, Sankilampi U, Vanamo K, Gissler M, Hyv\u00e4rinen A, Helenius I (2020) Omphalocele in Finland from 1993 to 2014: trends, prevalence, mortality, and associated malformations-a population-based study. Eur J Pediatr Surg 2020. https:\/\/doi.org\/10.1055\/s-0040-1703012","DOI":"10.1055\/s-0040-1703012"},{"key":"4005_CR3","doi-asserted-by":"publisher","first-page":"2399","DOI":"10.1016\/j.jpedsurg.2018.08.035","volume":"53","author":"JE Anderson","year":"2018","unstructured":"Anderson JE, Galganski LA, Cheng Y, Stark RA, Saadai P, Stephenson JT, Hirose S (2018) Epidemiology of gastroschisis: a population-based study in California from 1995 to 2012. J Pediatr Surg 53:2399\u20132403","journal-title":"J Pediatr Surg"},{"key":"4005_CR4","doi-asserted-by":"publisher","unstructured":"De Bie F, Swaminathan V, Johnson G, Monos S, Adzick NS, Laje P (2020) Long-term core outcomes of patients with simple gastroschisis. J Pediatr Surg. https:\/\/doi.org\/10.1016\/j.jpedsurg.2020.09.008","DOI":"10.1016\/j.jpedsurg.2020.09.008"},{"key":"4005_CR5","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1016\/s0022-3468(86)80360-8","volume":"21","author":"S Yazbeck","year":"1986","unstructured":"Yazbeck S, Ndoye M, Khan AH (1986) Omphalocele: a 25-year experience. J Pediatr Surg 21:761\u2013763. https:\/\/doi.org\/10.1016\/s0022-3468(86)80360-8","journal-title":"J Pediatr Surg"},{"key":"4005_CR6","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/s0003-3995(01)01094-2","volume":"44","author":"C Stoll","year":"2001","unstructured":"Stoll C, Alembik Y, Dott B, Roth MP (2001) Risk factors in congenital abdominal wall defects (omphalocele and gastroschisi): a study in a series of 265,858 consecutive births. Ann Genet 44:201\u2013208. https:\/\/doi.org\/10.1016\/s0003-3995(01)01094-2","journal-title":"Ann Genet"},{"key":"4005_CR7","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1016\/s0022-3468(99)90582-1","volume":"34","author":"A Koivusalo","year":"1999","unstructured":"Koivusalo A, Rintala R, Lindahl H (1999) Gastroesophageal reflux in children with a congenital abdominal wall defect. J Pediatr Surg 34:1127\u20131129. https:\/\/doi.org\/10.1016\/s0022-3468(99)90582-1","journal-title":"J Pediatr Surg"},{"key":"4005_CR8","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1002\/pd.894","volume":"24","author":"JM Biard","year":"2004","unstructured":"Biard JM, Wilson RD, Johnson MP, Hedrick HL, Schwarz U, Flake AW, Crombleholme TM, Adzick NS (2004) Prenatally diagnosed giant omphaloceles: short- and long-term outcomes. Prenat Diagn 24:434\u2013439. https:\/\/doi.org\/10.1002\/pd.894","journal-title":"Prenat Diagn"},{"key":"4005_CR9","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.siny.2011.02.003","volume":"16","author":"ER Christison-Lagay","year":"2011","unstructured":"Christison-Lagay ER, Kelleher CM, Langer JC (2011) Neonatal abdominal wall defects. Semin Fetal Neonatal Med 16:164\u2013172. https:\/\/doi.org\/10.1016\/j.siny.2011.02.003","journal-title":"Semin Fetal Neonatal Med"},{"key":"4005_CR10","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1186\/1471-2431-9-32","volume":"9","author":"L Colvin","year":"2009","unstructured":"Colvin L, Bower C (2009) A retrospective population-based study of childhood hospital admissions with record linkage to a birth defects registry. BMC Pediatr 9:32. https:\/\/doi.org\/10.1186\/1471-2431-9-32","journal-title":"BMC Pediatr"},{"key":"4005_CR11","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1136\/hrt.2006.113787","volume":"94","author":"J Billett","year":"2008","unstructured":"Billett J, Majeed A, Gatzoulis M, Cowie M (2008) Trends in hospital admissions, in-hospital case fatality and population mortality from congenital heart disease in England, 1994 to 2004. Heart 94:342\u2013348. https:\/\/doi.org\/10.1136\/hrt.2006.113787","journal-title":"Heart"},{"key":"4005_CR12","doi-asserted-by":"publisher","first-page":"e70401","DOI":"10.1371\/journal.pone.0070401","volume":"8","author":"P Fitzgerald","year":"2013","unstructured":"Fitzgerald P, Leonard H, Pikora TJ, Bourke J, Hammond G (2013) Hospital admissions in children with down syndrome: experience of a population-based cohort followed from birth. PLoS One 8:e70401. https:\/\/doi.org\/10.1371\/journal.pone.0070401","journal-title":"PLoS One"},{"key":"4005_CR13","doi-asserted-by":"publisher","first-page":"970","DOI":"10.1136\/archdischild-2013-304271","volume":"98","author":"KJ Fitzsimons","year":"2013","unstructured":"Fitzsimons KJ, Copley LP, Deacon SA, van der Meulen JH (2013) Hospital care of children with a cleft in England. Arch Dis Child 98:970\u2013974. https:\/\/doi.org\/10.1136\/archdischild-2013-304271","journal-title":"Arch Dis Child"},{"key":"4005_CR14","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1177\/1457496918812233","volume":"108","author":"J Syv\u00e4nen","year":"2019","unstructured":"Syv\u00e4nen J, Helenius I, Koskimies-Virta E, Ritvanen A, Hurme S, Nietosvaara Y (2019) Hospital admissions and surgical treatment of children with lower-limb deficiency in Finland. Scand J Surg 108:352\u2013360. https:\/\/doi.org\/10.1177\/1457496918812233","journal-title":"Scand J Surg"},{"key":"4005_CR15","doi-asserted-by":"publisher","first-page":"1682","DOI":"10.1016\/j.jpedsurg.2013.01.021","volume":"48","author":"M van Manen","year":"2013","unstructured":"van Manen M, Hendson L, Wiley M, Evans M, Taghaddos S, Dinu I (2013) Early childhood outcomes of infants born with gastroschisis. J Pediatr Surg 48:1682\u20131687. https:\/\/doi.org\/10.1016\/j.jpedsurg.2013.01.021","journal-title":"J Pediatr Surg"},{"key":"4005_CR16","doi-asserted-by":"publisher","first-page":"1466","DOI":"10.1016\/j.jpedsurg.2014.03.008","volume":"49","author":"EL Harris","year":"2014","unstructured":"Harris EL, Minutillo C, Hart S, Warner TM, Ravikumara M, Nathan EA, Dickinson JE (2014) The long term physical consequences of gastroschisis. J Pediatr Surg 49:1466\u20131470. https:\/\/doi.org\/10.1016\/j.jpedsurg.2014.03.008","journal-title":"J Pediatr Surg"},{"key":"4005_CR17","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1016\/j.jpedsurg.2016.08.022","volume":"52","author":"K Risby","year":"2017","unstructured":"Risby K, Husby S, Qvist N, Jakobsen MS (2017) High mortality among children with gastroschisis after the neonatal period: a long-term follow-up study. J Pediatr Surg 52:431\u2013436. https:\/\/doi.org\/10.1016\/j.jpedsurg.2016.08.022","journal-title":"J Pediatr Surg"},{"key":"4005_CR18","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.earlhumdev.2016.10.002","volume":"103","author":"CC Lap","year":"2016","unstructured":"Lap CC, Brizot ML, Pistorius LR, Kramer WL, Teeuwen IB, Eijkemans MJ, Brouwers HA, Pajkrt E, van Kaam AH, van Scheltema PN, Eggink AJ, van Heijst AF, Haak MC, van Weissenbruch MM, Sleeboom C, Willekes C, van der Hoeven MA, van Heurn EL, Bilardo CM, Dijk PH, van Baren R, Francisco RP, Tannuri AC, Visser GH, Manten GT (2016) Outcome of isolated gastroschisis; an international study, systematic review and meta-analysis. Early Hum Dev 103:209\u2013218. https:\/\/doi.org\/10.1016\/j.earlhumdev.2016.10.002","journal-title":"Early Hum Dev"},{"key":"4005_CR19","unstructured":"EUROCAT European Surveillance of Congenital Anomalies. www.eurocat-network.eu. Accessed 7 Jan 2021"},{"key":"4005_CR20","doi-asserted-by":"publisher","first-page":"1834","DOI":"10.1002\/ajmg.a.31381","volume":"140A","author":"N Pakkasj\u00e4rvi","year":"2006","unstructured":"Pakkasj\u00e4rvi N, Ritvanen A, Herva R, Peltonen L, Kestil\u00e4 M, Ignatius J (2006) Lethal congenital contracture syndrome (LCCS) and other lethal arthrogryposes in Finland--an epidemiological study. Am J Med Genet A 140A:1834\u20131839. https:\/\/doi.org\/10.1002\/ajmg.a.31381","journal-title":"Am J Med Genet A"},{"key":"4005_CR21","doi-asserted-by":"publisher","first-page":"1670","DOI":"10.1002\/ajmg.a.33493","volume":"152A","author":"E Leoncini","year":"2010","unstructured":"Leoncini E, Botto LD, Cocchi G, Anneren G, Bower C, Halliday J, Amar E et al (2010) How valid are the rates of Down syndrome internationally? Findings from the International Clearinghouse for Birth Defects Surveillance and Research. Am J Med Genet A 152A:1670\u20131680. https:\/\/doi.org\/10.1002\/ajmg.a.33493","journal-title":"Am J Med Genet A"},{"key":"4005_CR22","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1177\/140349489502300113","volume":"23","author":"M Gissler","year":"1995","unstructured":"Gissler M, Teperi J, Hemminki E, Merilainen J (1995) Data quality after restructuring a national medical registry. Scand J Soc Med 23:75\u201380. https:\/\/doi.org\/10.1177\/140349489502300113","journal-title":"Scand J Soc Med"},{"issue":"Suppl 1","key":"4005_CR23","doi-asserted-by":"publisher","first-page":"S51","DOI":"10.1002\/bdra.20775","volume":"91","author":"R Greenlees","year":"2011","unstructured":"Greenlees R, Neville A, Addor MC, Amar E, Arriola L, Bakker M, Barisic I, Boyd PA, Calzolari E, Doray B, Draper E, Emil Vollset S, Garne E, Gatt M, Haeusler M, Kallen K, Khoshnood B, Latos-Bielenska A, Martinez-Frias ML, Materna-Kiryluk A, Matias Dias C, McDonnell B, Mullaney C, Nelen V, O'Mahony M, Pierini A, Queisser-Luft A, Randrianaivo-Ranjato\u00e9lina H, Rankin J, Rissmann A, Ritvanen A, Salvador J, Sipek A, Tucker D, Verellen-Dumoulin C, Wellesley D, Wertelecki W (2011) Paper 6: EUROCAT member registries: organization and activities. Birth Defects Res A Clin Mol Teratol 91(Suppl 1):S51\u2013S100. https:\/\/doi.org\/10.1002\/bdra.20775","journal-title":"Birth Defects Res A Clin Mol Teratol"},{"key":"4005_CR24","doi-asserted-by":"publisher","first-page":"1280","DOI":"10.1002\/ajmg.a.32297","volume":"146A","author":"C Stoll","year":"2008","unstructured":"Stoll C, Alembik Y, Dott B, Roth MP (2008) Omphalocele and gastroschisis and associated malformations. Am J Med Genet A 146A:1280\u20131285. https:\/\/doi.org\/10.1002\/ajmg.a.32297","journal-title":"Am J Med Genet A"},{"key":"4005_CR25","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1186\/1471-2431-14-160","volume":"14","author":"K Deng","year":"2014","unstructured":"Deng K, Qiu J, Dai L, Yi L, Deng C, Mu Y, Zhu J (2014) Perinatal mortality in pregnancies with omphalocele: data from the Chinese national birth defects monitoring network, 1996-2006. BMC Pediatr 14:160. https:\/\/doi.org\/10.1186\/1471-2431-14-160","journal-title":"BMC Pediatr"},{"key":"4005_CR26","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1046\/j.1365-3016.1998.00090.x","volume":"12","author":"R Byron-Scott","year":"1998","unstructured":"Byron-Scott R, Haan E, Chan A, Bower C, Scott H, Clark K (1998) A population-based study of abdominal wall defects in South Australia and Western Australia. Paediatr Perinat Epidemiol 12:136\u2013151. https:\/\/doi.org\/10.1046\/j.1365-3016.1998.00090.x","journal-title":"Paediatr Perinat Epidemiol"},{"key":"4005_CR27","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1007\/s00383-016-3906-1","volume":"32","author":"LG Tullie","year":"2016","unstructured":"Tullie LG, Bough GM, Shalaby A, Kiely EM, Curry JI, Pierro A, De Coppi P, Cross KM (2016) Umbilical hernia following gastroschisis closure: a common event? Pediatr Surg Int 32:811\u2013814. https:\/\/doi.org\/10.1007\/s00383-016-3906-1","journal-title":"Pediatr Surg Int"},{"key":"4005_CR28","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1001\/jamasurg.2018.3216","volume":"154","author":"RG Witt","year":"2019","unstructured":"Witt RG, Zobel M, Padilla B, Lee H, MacKenzie TC, Vu L (2019) Evaluation of clinical outcomes of sutureless vs sutured closure techniques in gastroschisis repair. JAMA Surg 154:33\u201339. https:\/\/doi.org\/10.1001\/jamasurg.2018.3216","journal-title":"JAMA Surg"},{"key":"4005_CR29","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1016\/j.jpedsurg.2016.02.012","volume":"51","author":"JL Carpenter","year":"2016","unstructured":"Carpenter JL, Wiebe TL, Cass DL, Olutoye OO, Lee TC (2016) Assessing quality of life in pediatric gastroschisis patients using the Pediatric Quality of Life Inventory survey: an institutional study. J Pediatr Surg 51:726\u2013729. https:\/\/doi.org\/10.1016\/j.jpedsurg.2016.02.012","journal-title":"J Pediatr Surg"},{"key":"4005_CR30","doi-asserted-by":"publisher","unstructured":"Raitio A, Syv\u00e4nen J, Tauriainen A, Hyv\u00e4rinen A, Sankilampi U, Gissler M, Helenius I (2021) Congenital abdominal wall defects and cryptorchidism: a population-based study. Pediatr Surg Int 2021. https:\/\/doi.org\/10.1007\/s00383-021-04863-9","DOI":"10.1007\/s00383-021-04863-9"},{"key":"4005_CR31","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1097\/00000658-199505000-00010","volume":"221","author":"WP Tunell","year":"1995","unstructured":"Tunell WP, Puffinbarger NK, Tuggle DW, Taylor DV, Mantor PC (1995) Abdominal wall defects in infants. Survival and implications for adult life. Ann Surg 221:525\u2013528; discussion 528-530. https:\/\/doi.org\/10.1097\/00000658-199505000-00010","journal-title":"Ann Surg"},{"key":"4005_CR32","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/j.jpedsurg.2007.10.027","volume":"43","author":"FC van Eijck","year":"2008","unstructured":"van Eijck FC, Wijnen RM, van Goor H (2008) The incidence and morbidity of adhesions after treatment of neonates with gastroschisis and omphalocele: a 30-year review. J Pediatr Surg 43:479\u2013483. https:\/\/doi.org\/10.1016\/j.jpedsurg.2007.10.027","journal-title":"J Pediatr Surg"},{"key":"4005_CR33","doi-asserted-by":"publisher","first-page":"1725","DOI":"10.1016\/j.jpedsurg.2016.07.006","volume":"51","author":"B Bauman","year":"2016","unstructured":"Bauman B, Stephens D, Gershone H, Bongiorno C, Osterholm E, Acton R, Hess D, Saltzman D, Segura B (2016) Management of giant omphaloceles: a systematic review of methods of staged surgical vs. nonoperative delayed closure. J Pediatr Surg 51:1725\u20131730. https:\/\/doi.org\/10.1016\/j.jpedsurg.2016.07.006","journal-title":"J Pediatr Surg"},{"key":"4005_CR34","unstructured":"THL Register of Congenital Malformations. Finnish Institute for Health and Welfare. https:\/\/thl.fi\/en\/web\/thlfi-en\/statistics\/information-on-statistics\/register-descriptions\/register-of-congenital-malformations. Accessed 2020, Nov 10."},{"key":"4005_CR35","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1177\/1403494812456637","volume":"40","author":"R Sund","year":"2012","unstructured":"Sund R (2012) Quality of the Finnish Hospital Discharge Register: a systematic review. Scand J Public Health 40:505\u2013515. https:\/\/doi.org\/10.1177\/1403494812456637","journal-title":"Scand J Public Health"},{"key":"4005_CR36","unstructured":"THL Care Register for Health Care. https:\/\/thl.fi\/en\/web\/thlfi-en\/statistics\/information-on-statistics\/register-descriptions\/care-register-for-health-care. Accessed 2020, Nov 30."}],"container-title":["European Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-021-04005-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00431-021-04005-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-021-04005-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T10:10:20Z","timestamp":1623406220000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00431-021-04005-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,5]]},"references-count":36,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["4005"],"URL":"https:\/\/doi.org\/10.1007\/s00431-021-04005-2","relation":{},"ISSN":["0340-6199","1432-1076"],"issn-type":[{"value":"0340-6199","type":"print"},{"value":"1432-1076","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,5]]},"assertion":[{"value":"21 January 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 February 2021","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 February 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 March 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors. The Institute for Health and Welfare and Institutional Review board at Turku University Hospital approved this national register-based study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors report no conflicts of interest related to the current study. IH has received funding from the Industry outside this study (Medtronic, Stryker).","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}