{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T14:00:41Z","timestamp":1790517641851,"version":"4.1.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2022,9,14]],"date-time":"2022-09-14T00:00:00Z","timestamp":1663113600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,9,14]],"date-time":"2022-09-14T00:00:00Z","timestamp":1663113600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"DOI":"10.1007\/s00431-022-04607-4","type":"journal-article","created":{"date-parts":[[2022,9,14]],"date-time":"2022-09-14T00:02:44Z","timestamp":1663113764000},"page":"3977-3983","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Association between respiratory rate oxygenation index and need for positive pressure ventilation in children on high flow nasal cannula for bronchiolitis"],"prefix":"10.1007","volume":"181","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6946-9857","authenticated-orcid":false,"given":"Nirupama","family":"Kannikeswaran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Whittaker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usha","family":"Sethuraman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,9,14]]},"reference":[{"key":"4607_CR1","unstructured":"Ralston SL, Lieberthal AS, Meissner HC et al (2014) American academy of pediatrics. Clinical practice guideline: the diagnosis, management, and prevention of bronchiolitis. Pediatrics\u00a0134(5):e1474\u2013e1502"},{"issue":"6","key":"4607_CR2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2020-039115","volume":"147","author":"JH Pelletier","year":"2021","unstructured":"Pelletier JH, Au AK, Fuhrman D et al (2021) Trends in bronchiolitis ICU admissions and ventilation practices: 2010\u20132019. Pediatrics 147(6):e2020039115","journal-title":"Pediatrics"},{"issue":"6","key":"4607_CR3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2019-2614","volume":"144","author":"M Fujiogi","year":"2019","unstructured":"Fujiogi M, Goto T, Yasunaga H et al (2019) Trends in bronchiolitis hospitalizations in the United States\u202f: 2010\u20132016. Pediatrics 144(6):e20192614","journal-title":"Pediatrics"},{"key":"4607_CR4","doi-asserted-by":"crossref","unstructured":"D\u2019Alessandro M, Vanniyasingam T, Patel A et al (2020) Factors associated with treatment failure of high-flow nasal cannula among children with bronchiolitis: a single- center retrospective study. Paediatr Child Health 26(5):e229\u2013e235","DOI":"10.1093\/pch\/pxaa087"},{"key":"4607_CR5","doi-asserted-by":"publisher","first-page":"e492","DOI":"10.1542\/peds.2012-0444","volume":"130","author":"JM Mansbach","year":"2012","unstructured":"Mansbach JM, Piedra PA, Stevenson MD et al (2012) Prospective multicenter study of children with bronchiolitis requiring mechanical ventilation. Pediatrics 130:e492-500","journal-title":"Pediatrics"},{"key":"4607_CR6","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1542\/hpeds.2017-0034","volume":"7","author":"NM Dadlez","year":"2017","unstructured":"Dadlez NM, Esteban-Cruciani N, Khan A et al (2017) Risk factors for respiratory decompensation among healthy infants with bronchiolitis. Hosp Pediatr 7:530\u2013535","journal-title":"Hosp Pediatr"},{"key":"4607_CR7","doi-asserted-by":"crossref","unstructured":"Abboud P, Roth PJ, Skiles Cl et al (2012) Predictors of failure in infants with viral bronchiolitis treated with high-flow, high-humidity nasal cannula therapy. Pediatr Crit Care Med\u00a013(6):e343\u2013e349","DOI":"10.1097\/PCC.0b013e31825b546f"},{"issue":"12","key":"4607_CR8","doi-asserted-by":"publisher","first-page":"2500","DOI":"10.1016\/j.ajem.2019.12.017","volume":"38","author":"A Suessman","year":"2020","unstructured":"Suessman A, Gray LL, Cavenaugh S et al (2020) Clinical factors associated with intubation in the high flow nasal cannula era. Am J Emerg Med 38(12):2500\u20132505","journal-title":"Am J Emerg Med"},{"key":"4607_CR9","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/j.jcrc.2016.05.022","volume":"35","author":"O Roca","year":"2016","unstructured":"Roca O, Messika J, Caralt B et al (2016) Predicting success of high-flow nasal cannula in pneumonia patients with hypoxemic respiratory failure: The utility of the ROX index. J Crit Care 35:200\u2013205","journal-title":"J Crit Care"},{"issue":"11","key":"4607_CR10","doi-asserted-by":"publisher","first-page":"1368","DOI":"10.1164\/rccm.201803-0589OC","volume":"199","author":"O Roca","year":"2019","unstructured":"Roca O, Caralt B, Messika J et al (2019) An index combining respiratory rate and oxygenation to predict outcome of nasal high-flow therapy. Am J Respir Crit Care Med 199(11):1368\u20131376","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"4607_CR11","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1007\/s00431-020-03847-6","volume":"180","author":"D Yildizdas","year":"2021","unstructured":"Yildizdas D, Yontem A, Iplik G et al (2021) Predicting nasal high-flow therapy failure by pediatric respiratory rate-oxygenation index and pediatric respiratory rate-oxygenation index variation in children. Eur J Pediatr 180(4):1099\u20131106","journal-title":"Eur J Pediatr"},{"key":"4607_CR12","doi-asserted-by":"publisher","DOI":"10.1002\/9781118548387","volume-title":"Applied logistic regression","author":"DWJ Hosmer","year":"2013","unstructured":"Hosmer DWJ, Lemeshow S, Sturdivant RX (2013) Applied logistic regression, 3rd edn. John Wiley & Sons, Hoboken, NJ","edition":"3"},{"key":"4607_CR13","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1016\/j.jcrc.2021.08.012","volume":"66","author":"J Prakash","year":"2021","unstructured":"Prakash J, Bhattacharya PK, Yadav AK et al (2021) ROX index as a good predictor of high flow nasal cannula failure in COVID-19 patients with acute hypoxemic respiratory failure: A systematic review and meta-analysis. J Crit Care 66:102\u2013108","journal-title":"J Crit Care"},{"issue":"10","key":"4607_CR14","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.3109\/02770903.2013.834504","volume":"50","author":"DM Duarte-Dorado","year":"2013","unstructured":"Duarte-Dorado DM, Madero-Orestegui DS, Rodriguez-Martinez CE et al (2013) Validation of a scale to assess the severity of bronchiolitis in a population of hospitalized infants. J Asthma 50(10):1056\u20131061","journal-title":"J Asthma"},{"issue":"1","key":"4607_CR15","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1164\/ajrccm\/145.1.106","volume":"145","author":"EE Wang","year":"1992","unstructured":"Wang EE, Milner RA, Navas L et al (1992) Observer agreement for respiratory signs and oximetry in infants hospitalized with lower respiratory infections. Am Rev Respir Dis 145(1):106\u2013109","journal-title":"Am Rev Respir Dis"},{"issue":"6","key":"4607_CR16","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1542\/peds.79.6.939","volume":"79","author":"DI Lowell","year":"1987","unstructured":"Lowell DI, Lister G, Von Koss H et al (1987) Wheezing in infants: the response to epinephrine. Pediatrics 79(6):939\u2013945","journal-title":"Pediatrics"},{"key":"4607_CR17","doi-asserted-by":"crossref","unstructured":"Mount MC, Ji X, Kattan MW et al (2022) Derivation and validation of the critical bronchiolitis score for the PICU. Pediatr Crit Care Med 1;23(1):e45\u2013e54","DOI":"10.1097\/PCC.0000000000002808"},{"issue":"3","key":"4607_CR18","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2017-4253","volume":"142","author":"G Friere","year":"2018","unstructured":"Friere G, Kuppermann N, Zemek R et al (2018) Predicting escalated care in infants with bronchiolitis. Pediatrics 142(3):e20174253","journal-title":"Pediatrics"}],"container-title":["European Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-022-04607-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00431-022-04607-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-022-04607-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T20:04:37Z","timestamp":1744142677000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00431-022-04607-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,14]]},"references-count":18,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2022,11]]}},"alternative-id":["4607"],"URL":"https:\/\/doi.org\/10.1007\/s00431-022-04607-4","relation":{},"ISSN":["1432-1076"],"issn-type":[{"value":"1432-1076","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,14]]},"assertion":[{"value":"3 June 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 August 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 September 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 September 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by our Institutional Review Board (011718MP4E).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"All parent provided written informed consent for participation in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"N\/A","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}