{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T16:50:50Z","timestamp":1767891050789,"version":"3.49.0"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T00:00:00Z","timestamp":1668384000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T00:00:00Z","timestamp":1668384000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"DOI":"10.1007\/s00431-022-04700-8","type":"journal-article","created":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T08:08:48Z","timestamp":1668413328000},"page":"403-409","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Health-related quality of life 6\u00a0months after pediatric intensive care unit admission for bronchiolitis: a prospective single-center cohort study"],"prefix":"10.1007","volume":"182","author":[{"given":"Tessel","family":"van Dijk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milou V.","family":"van Benthum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nienke M.","family":"Maas-van Schaaijk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3443-0952","authenticated-orcid":false,"given":"Annelies","family":"van Zwol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,11,14]]},"reference":[{"issue":"7","key":"4700_CR1","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1007\/s00134-015-3780-7","volume":"41","author":"F Aspesberro","year":"2015","unstructured":"Aspesberro F, Mangione-Smith R, Zimmerman JJ (2015) Health-related quality of life following pediatric critical illness. Intensive Care Med 41(7):1235\u20131246. https:\/\/doi.org\/10.1007\/s00134-015-3780-7","journal-title":"Intensive Care Med"},{"issue":"11","key":"4700_CR2","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1007\/s00431-007-0573-1","volume":"166","author":"H Knoester","year":"2007","unstructured":"Knoester H, Grootenhuis MA, Bos AP (2007) Outcome of paediatric intensive care survivors. Eur J Pediatr 166(11):1119\u20131128. https:\/\/doi.org\/10.1007\/s00431-007-0573-1","journal-title":"Eur J Pediatr"},{"issue":"9","key":"4700_CR3","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1097\/00003246-199009000-00011","volume":"18","author":"W Butt","year":"1990","unstructured":"Butt W, Shann F, Tibballs J, Williams J, Cuddihy L, Blewett L, Farley M (1990) Long-term outcome of children after intensive care. Crit Care Med 18(9):961\u2013965. https:\/\/doi.org\/10.1097\/00003246-199009000-00011","journal-title":"Crit Care Med"},{"key":"4700_CR4","unstructured":"Visser I, PICE Working Group (2011) Pediatric intensive care evaluation annual report. Rotterdam: PICE foundation"},{"issue":"4","key":"4700_CR5","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1097\/pcc.0000000000001476","volume":"19","author":"JC Manning","year":"2018","unstructured":"Manning JC, Pinto NP, Rennick JE, Colville G, Curley MAQ (2018) Conceptualizing post intensive care syndrome in children-the PICS-p framework. Pediatr Crit Care Med 19(4):298\u2013300. https:\/\/doi.org\/10.1097\/pcc.0000000000001476","journal-title":"Pediatr Crit Care Med"},{"issue":"2","key":"4700_CR6","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1097\/CCM.0b013e318232da75","volume":"40","author":"DM Needham","year":"2012","unstructured":"Needham DM, Davidson J, Cohen H, Hopkins RO, Weinert C, Wunsch H, Zawistowski C, Bemis-Dougherty A, Berney SC, Bienvenu OJ et al (2012) Improving long-term outcomes after discharge from intensive care unit: report from a stakeholders\u2019 conference. Crit Care Med 40(2):502\u2013509. https:\/\/doi.org\/10.1097\/CCM.0b013e318232da75","journal-title":"Crit Care Med"},{"key":"4700_CR7","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.jpeds.2017.12.084","volume":"198","author":"RS Watson","year":"2018","unstructured":"Watson RS, Choong K, Colville G, Crow S, Dervan LA, Hopkins RO, Knoester H, Pollack MM, Rennick J, Curley MAQ (2018) Life after critical illness in children-toward an understanding of pediatric post-intensive care syndrome. J Pediatr 198:16\u201324. https:\/\/doi.org\/10.1016\/j.jpeds.2017.12.084","journal-title":"J Pediatr"},{"issue":"1","key":"4700_CR8","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1186\/s13054-020-03059-2","volume":"24","author":"J Hordijk","year":"2020","unstructured":"Hordijk J, Verbruggen S, Vanhorebeek I, G\u00fciza F, Wouters P, Van den Berghe G, Joosten K, Dulfer K (2020) Health-related quality of life of children and their parents 2 years after critical illness: pre-planned follow-up of the PEPaNIC international, randomized, controlled trial. Crit Care 24(1):347. https:\/\/doi.org\/10.1186\/s13054-020-03059-2","journal-title":"Crit Care"},{"issue":"1","key":"4700_CR9","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1007\/s11136-019-02347-x","volume":"29","author":"J Hordijk","year":"2020","unstructured":"Hordijk J, Verbruggen S, Vanhorebeek I, Van den Berghe G, Utens E, Joosten K, Dulfer K (2020) Health-related quality of life of children and their parents 6 months after children\u2019s critical illness. Qual Life Res 29(1):179\u2013189. https:\/\/doi.org\/10.1007\/s11136-019-02347-x","journal-title":"Qual Life Res"},{"issue":"11","key":"4700_CR10","doi-asserted-by":"publisher","first-page":"e513","DOI":"10.1097\/pcc.0000000000000956","volume":"17","author":"NJ Vet","year":"2016","unstructured":"Vet NJ, de Wildt SN, Verlaat CW, Mooij MG, Tibboel D, de Hoog M, Buysse CM (2016) Short-term health-related quality of life of critically ill children following daily sedation interruption. Pediatr Crit Care Med 17(11):e513\u2013e520. https:\/\/doi.org\/10.1097\/pcc.0000000000000956","journal-title":"Pediatr Crit Care Med"},{"issue":"2","key":"4700_CR11","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/s2213-2600(19)30445-x","volume":"8","author":"RA Bem","year":"2020","unstructured":"Bem RA, Bont LJ, van Woensel JBM (2020) Life-threatening bronchiolitis in children: eight decades of critical care. Lancet Respiratory Med 8(2):142\u2013144. https:\/\/doi.org\/10.1016\/s2213-2600(19)30445-x","journal-title":"Lancet Respiratory Medicine"},{"issue":"12","key":"4700_CR12","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.1097\/pcc.0000000000001337","volume":"18","author":"SL Shein","year":"2017","unstructured":"Shein SL, Slain KN, Clayton JA, McKee B, Rotta AT, Wilson-Costello D (2017) Neurologic and functional morbidity in critically ill children with bronchiolitis. Pediatr Crit Care Med 18(12):1106\u20131113. https:\/\/doi.org\/10.1097\/pcc.0000000000001337","journal-title":"Pediatr Crit Care Med"},{"issue":"1","key":"4700_CR13","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1056\/NEJMra1413456","volume":"374","author":"HC Meissner","year":"2016","unstructured":"Meissner HC (2016) Viral bronchiolitis in children. N Engl J Med 374(1):62\u201372. https:\/\/doi.org\/10.1056\/NEJMra1413456","journal-title":"N Engl J Med"},{"issue":"5","key":"4700_CR14","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1002\/ppul.21389","volume":"46","author":"T Principi","year":"2011","unstructured":"Principi T, Fraser DD, Morrison GC, Farsi SA, Carrelas JF, Maurice EA, Kornecki A (2011) Complications of mechanical ventilation in the pediatric population. Pediatr Pulmonol 46(5):452\u2013457. https:\/\/doi.org\/10.1002\/ppul.21389","journal-title":"Pediatr Pulmonol"},{"issue":"5","key":"4700_CR15","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1097\/00003246-199605000-00004","volume":"24","author":"MM Pollack","year":"1996","unstructured":"Pollack MM, Patel KM, Ruttimann UE (1996) PRISM III: an updated pediatric risk of mortality score. Crit Care Med 24(5):743\u2013752. https:\/\/doi.org\/10.1097\/00003246-199605000-00004","journal-title":"Crit Care Med"},{"issue":"2","key":"4700_CR16","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1007\/s00134-002-1601-2","volume":"29","author":"A Slater","year":"2003","unstructured":"Slater A, Shann F, Pearson G (2003) PIM2: a revised version of the paediatric index of mortality. Intensive Care Med 29(2):278\u2013285. https:\/\/doi.org\/10.1007\/s00134-002-1601-2","journal-title":"Intensive Care Med"},{"issue":"4","key":"4700_CR17","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1136\/adc.2003.048645","volume":"90","author":"EM Bunge","year":"2005","unstructured":"Bunge EM, Essink-Bot ML, Kobussen MP, van Suijlekom-Smit LW, Moll HA, Raat H (2005) Reliability and validity of health status measurement by the TAPQOL. Arch Dis Child 90(4):351\u2013358. https:\/\/doi.org\/10.1136\/adc.2003.048645","journal-title":"Arch Dis Child"},{"issue":"8","key":"4700_CR18","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1023\/a:1008981603178","volume":"9","author":"M Fekkes","year":"2000","unstructured":"Fekkes M, Theunissen NC, Brugman E, Veen S, Verrips EG, Koopman HM, Vogels T, Wit JM, Verloove-Vanhorick SP (2000) Development and psychometric evaluation of the TAPQOL: a health-related quality of life instrument for 1\u20135-year-old children. Qual Life Res 9(8):961\u2013972. https:\/\/doi.org\/10.1023\/a:1008981603178","journal-title":"Qual Life Res"},{"issue":"7","key":"4700_CR19","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1017\/s0012162201000846","volume":"43","author":"NC Theunissen","year":"2001","unstructured":"Theunissen NC, Veen S, Fekkes M, Koopman HM, Zwinderman KA, Brugman E, Wit JM (2001) Quality of life in preschool children born preterm. Dev Med Child Neurol 43(7):460\u2013465. https:\/\/doi.org\/10.1017\/s0012162201000846","journal-title":"Dev Med Child Neurol"},{"key":"4700_CR20","unstructured":"Fekkes M, Bruil J, Vogels T (2003) TAPQOL-manual Leiden. TNO Prevention and Health"},{"key":"4700_CR21","volume-title":"Statistical power analysis for the bevaioral sciences","author":"J Cohen","year":"1988","unstructured":"Cohen J (1988) Statistical power analysis for the bevaioral sciences. Academy Press, New York"},{"key":"4700_CR22","unstructured":"Kunst AE, Dalstra JAA, Bos V, Machenbach JP (2005) Ontwikkeling en toepassing van indicatoren van sociaal-economische status binnen het Gezondheidsstatistisch Bestand. In U. M. C. R. Afdeling Maatschappelijke Gezondheidszorg (Ed.): Centraal Bureau voor de Statisiek"},{"key":"4700_CR23","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/1477-7525-6-21","volume":"6","author":"H Knoester","year":"2008","unstructured":"Knoester H, Bronner MB, Bos AP, Grootenhuis MA (2008) Quality of life in children three and nine months after discharge from a paediatric intensive care unit: a prospective cohort study. Health Qual Life Outcomes 6:21. https:\/\/doi.org\/10.1186\/1477-7525-6-21","journal-title":"Health Qual Life Outcomes"},{"issue":"7","key":"4700_CR24","doi-asserted-by":"publisher","first-page":"659","DOI":"10.2165\/00019053-200523070-00003","volume":"23","author":"M De Civita","year":"2005","unstructured":"De Civita M, Regier D, Alamgir AH, Anis AH, Fitzgerald MJ, Marra CA (2005) Evaluating health-related quality-of-life studies in paediatric populations: some conceptual, methodological and developmental considerations and recent applications. Pharmacoeconomics 23(7):659\u2013685. https:\/\/doi.org\/10.2165\/00019053-200523070-00003","journal-title":"Pharmacoeconomics"},{"issue":"1","key":"4700_CR25","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1186\/s12955-017-0654-4","volume":"15","author":"SA Schepers","year":"2017","unstructured":"Schepers SA, van Oers HA, Maurice-Stam H, Huisman J, Verhaak CM, Grootenhuis MA, Haverman L (2017) Health related quality of life in Dutch infants, toddlers, and young children. Health Qual Life Outcomes 15(1):81. https:\/\/doi.org\/10.1186\/s12955-017-0654-4","journal-title":"Health Qual Life Outcomes"},{"issue":"21\u201322","key":"4700_CR26","first-page":"312","volume":"137","author":"J Ambuehl","year":"2007","unstructured":"Ambuehl J, Karrer A, Meer A, Riedel T, Schibler A (2007) Quality of life of survivors of paediatric intensive care. Swiss Med Wkly 137(21\u201322):312\u2013316","journal-title":"Swiss Med Wkly"},{"issue":"3","key":"4700_CR27","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1136\/adc.73.3.196","volume":"73","author":"RJ Gemke","year":"1995","unstructured":"Gemke RJ, Bonsel GJ, van Vught AJ (1995) Long-term survival and state of health after paediatric intensive care. Arch Dis Child 73(3):196\u2013201. https:\/\/doi.org\/10.1136\/adc.73.3.196","journal-title":"Arch Dis Child"},{"issue":"5","key":"4700_CR28","doi-asserted-by":"publisher","first-page":"2101","DOI":"10.1542\/peds.2006-1455","volume":"118","author":"S Jones","year":"2006","unstructured":"Jones S, Rantell K, Stevens K, Colwell B, Ratcliffe JR, Holland P, Rowan K, Parry GJ (2006) Outcome at 6 months after admission for pediatric intensive care: a report of a national study of pediatric intensive care units in the United kingdom. Pediatrics 118(5):2101\u20132108. https:\/\/doi.org\/10.1542\/peds.2006-1455","journal-title":"Pediatrics"},{"issue":"5","key":"4700_CR29","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1007\/s00134-003-1690-6","volume":"29","author":"A Taylor","year":"2003","unstructured":"Taylor A, Butt W, Ciardulli M (2003) The functional outcome and quality of life of children after admission to an intensive care unit. Intensive Care Med 29(5):795\u2013800. https:\/\/doi.org\/10.1007\/s00134-003-1690-6","journal-title":"Intensive Care Med"},{"key":"4700_CR30","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1186\/1477-7525-1-54","volume":"1","author":"J Horsman","year":"2003","unstructured":"Horsman J, Furlong W, Feeny D, Torrance G (2003) The health utilities index (HUI): concepts, measurement properties and applications. Health Qual Life Outcomes 1:54. https:\/\/doi.org\/10.1186\/1477-7525-1-54","journal-title":"Health Qual Life Outcomes"},{"issue":"5","key":"4700_CR31","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.1111\/apa.16272","volume":"111","author":"MV van Benthum","year":"2022","unstructured":"van Benthum MV, van Dijk T, Maas-van Schaaijk NM, van Zwol A (2022) Psychological problems in parents of children with bronchiolitis following paediatric intensive care unit (PICU) admission. Acta Paediatr 111(5):1054\u20131055. https:\/\/doi.org\/10.1111\/apa.16272","journal-title":"Acta Paediatr"},{"issue":"2","key":"4700_CR32","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1097\/pcc.0000000000001421","volume":"19","author":"K Choong","year":"2018","unstructured":"Choong K, Fraser D, Al-Harbi S, Borham A, Cameron J, Cameron S, Cheng J, Clark H, Doherty T, Fayed N et al (2018) Functional recovery in critically ill children, the \u201cWeeCover\u201d multicenter study. Pediatr Crit Care Med 19(2):145\u2013154. https:\/\/doi.org\/10.1097\/pcc.0000000000001421","journal-title":"Pediatr Critical Care Medicine"},{"issue":"1","key":"4700_CR33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/00130478-200201000-00001","volume":"3","author":"AL Morrison","year":"2002","unstructured":"Morrison AL, Gillis J, O\u2019Connell AJ, Schell DN, Dossetor DR, Mellis C (2002) Quality of life of survivors of pediatric intensive care. Pediatr Crit Care Med 3(1):1\u20135. https:\/\/doi.org\/10.1097\/00130478-200201000-00001","journal-title":"Pediatr Crit Care Med"},{"issue":"1","key":"4700_CR34","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1007\/s00431-012-1843-0","volume":"172","author":"B Polic","year":"2013","unstructured":"Polic B, Mestrovic J, Markic J, Mestrovic M, Capkun V, Utrobicic I, Jukica M, Radonic M (2013) Long-term quality of life of patients treated in paediatric intensive care unit. Eur J Pediatr 172(1):85\u201390. https:\/\/doi.org\/10.1007\/s00431-012-1843-0","journal-title":"Eur J Pediatr"},{"key":"4700_CR35","unstructured":"Statistical Office of the European Communities, Level of education of the mother (% of specified population) (2019) EUROSTAT: regional statistics. Accessed 14 June 2022 https:\/\/ec.europa.eu\/eurostat\/statistics-explained\/index.php?title=File:Level_of_education_of_the_mother,_2019_(%25_of_specified_population).png"},{"key":"4700_CR36","first-page":"D34","volume":"160","author":"SA de Laat","year":"2015","unstructured":"de Laat SA, Essink-Bot ML, van Wassenaer-Leemhuis AG, Vrijkotte TG (2015) Preterm birth and low socioeconomic status: more psychosocial problems at age 5\u20136? Ned Tijdschr Geneeskd 160:D34","journal-title":"Ned Tijdschr Geneeskd"}],"container-title":["European Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-022-04700-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00431-022-04700-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-022-04700-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T14:21:13Z","timestamp":1744208473000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00431-022-04700-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,14]]},"references-count":36,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,1]]}},"alternative-id":["4700"],"URL":"https:\/\/doi.org\/10.1007\/s00431-022-04700-8","relation":{},"ISSN":["1432-1076"],"issn-type":[{"value":"1432-1076","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,14]]},"assertion":[{"value":"14 July 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 October 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 November 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 November 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee of the Radboud University Medical Centre (file 202\u20136527) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from the parents.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}