{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T14:21:57Z","timestamp":1793283717835,"version":"4.5.0"},"reference-count":89,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2022,12,6]],"date-time":"2022-12-06T00:00:00Z","timestamp":1670284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,12,6]],"date-time":"2022-12-06T00:00:00Z","timestamp":1670284800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"DOI":"10.1007\/s00431-022-04743-x","type":"journal-article","created":{"date-parts":[[2022,12,6]],"date-time":"2022-12-06T11:50:52Z","timestamp":1670327452000},"page":"501-511","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Osteoporosis in children and adolescents: how to treat and monitor?"],"prefix":"10.1007","volume":"182","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0874-4648","authenticated-orcid":false,"given":"Silvia","family":"Ciancia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"H\u00f6gler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph J. B.","family":"Sakkers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha M.","family":"Appelman-Dijkstra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annemieke M.","family":"Boot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theo C. J.","family":"Sas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith S.","family":"Renes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,12,6]]},"reference":[{"key":"4743_CR1","doi-asserted-by":"publisher","first-page":"2549","DOI":"10.1007\/s00431-022-04455-2","volume":"181","author":"S Ciancia","year":"2022","unstructured":"Ciancia S, van Rijn RR, Hogler W, Appelman-Dijkstra NM, Boot AM, Sas TCJ, Renes JS (2022) Osteoporosis in children and adolescents: when to suspect and how to diagnose it. Eur J Pediatr 181:2549\u20132561. https:\/\/doi.org\/10.1007\/s00431-022-04455-2","journal-title":"Eur J Pediatr"},{"key":"4743_CR2","doi-asserted-by":"publisher","unstructured":"El-Gazzar A, Hogler W (2021) Mechanisms of bone fragility: from osteogenesis imperfecta to secondary osteoporosis Int J Mol Sci 22.\u00a0https:\/\/doi.org\/10.3390\/ijms22020625","DOI":"10.3390\/ijms22020625"},{"key":"4743_CR3","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1007\/s11914-014-0225-0","volume":"12","author":"A Biggin","year":"2014","unstructured":"Biggin A, Munns CF (2014) Osteogenesis imperfecta: diagnosis and treatment. Curr Osteoporos Rep 12:279\u2013288. https:\/\/doi.org\/10.1007\/s11914-014-0225-0","journal-title":"Curr Osteoporos Rep"},{"key":"4743_CR4","doi-asserted-by":"publisher","unstructured":"Hurley T, Zareen Z, Stewart P, McDonnell C, McDonald D, Molloy E (2021) Bisphosphonate use in children with cerebral palsy. Cochrane Database Syst Rev 7:CD012756. https:\/\/doi.org\/10.1002\/14651858.CD012756.pub2","DOI":"10.1002\/14651858.CD012756.pub2"},{"key":"4743_CR5","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1016\/j.ecl.2020.07.002","volume":"49","author":"DR Weber","year":"2020","unstructured":"Weber DR (2020) Bone health in childhood chronic disease. Endocrinol Metab Clin North Am 49:637\u2013650. https:\/\/doi.org\/10.1016\/j.ecl.2020.07.002","journal-title":"Endocrinol Metab Clin North Am"},{"key":"4743_CR6","doi-asserted-by":"publisher","unstructured":"Bell JM, Shields MD, Watters J, Hamilton A, Beringer T, Elliott M, Quinlivan R, Tirupathi S, Blackwood B (2017) Interventions to prevent and treat corticosteroid-induced osteoporosis and prevent osteoporotic fractures in Duchenne muscular dystrophy. Cochrane Database Syst Rev 1:CD010899. https:\/\/doi.org\/10.1002\/14651858.CD010899.pub2","DOI":"10.1002\/14651858.CD010899.pub2"},{"key":"4743_CR7","doi-asserted-by":"publisher","first-page":"R185","DOI":"10.1530\/EJE-14-0865","volume":"173","author":"V Saraff","year":"2015","unstructured":"Saraff V, Hogler W (2015) Osteoporosis in children: diagnosis and management. Eur J Endocrinol 173:R185-197. https:\/\/doi.org\/10.1530\/EJE-14-0865","journal-title":"Eur J Endocrinol"},{"key":"4743_CR8","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1016\/j.bone.2017.02.003","volume":"97","author":"LF Gonzalez Ballesteros","year":"2017","unstructured":"Gonzalez Ballesteros LF, Ma NS, Gordon RJ, Ward L, Backeljauw P, Wasserman H, Weber DR, DiMeglio LA, Gagne J, Stein R, Cody D, Simmons K, Zimakas P, Topor LS, Agrawal S, Calabria A, Tebben P, Faircloth R, Imel EA, Casey L, Carpenter TO (2017) Unexpected widespread hypophosphatemia and bone disease associated with elemental formula use in infants and children. Bone 97:287\u2013292. https:\/\/doi.org\/10.1016\/j.bone.2017.02.003","journal-title":"Bone"},{"key":"4743_CR9","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1542\/peds.2007-1894","volume":"122","author":"Misra M, Pacaud D, Petryk A, Collett-Solberg PF, Kappy M, Drug, Therapeutics Committee of the Lawson Wilkins Pediatric Endocrine S","year":"2008","unstructured":"Misra M, Pacaud D, Petryk A, Collett-Solberg PF, Kappy M, Drug, Therapeutics Committee of the Lawson Wilkins Pediatric Endocrine S (2008) Vitamin D deficiency in children and its management: review of current knowledge and recommendations. Pediatrics 122:398\u2013417. https:\/\/doi.org\/10.1542\/peds.2007-1894","journal-title":"Pediatrics"},{"key":"4743_CR10","doi-asserted-by":"publisher","first-page":"2161","DOI":"10.1002\/jbmr.2254","volume":"29","author":"VP Tan","year":"2014","unstructured":"Tan VP, Macdonald HM, Kim S, Nettlefold L, Gabel L, Ashe MC, McKay HA (2014) Influence of physical activity on bone strength in children and adolescents: a systematic review and narrative synthesis. Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research 29:2161\u20132181. https:\/\/doi.org\/10.1002\/jbmr.2254","journal-title":"Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research"},{"key":"4743_CR11","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1210\/jc.2015-2175","volume":"101","author":"CF Munns","year":"2016","unstructured":"Munns CF, Shaw N, Kiely M, Specker BL, Thacher TD, Ozono K, Michigami T et al (2016) Global consensus recommendations on prevention and management of nutritional rickets. J Clin Endocrinol Metab 101:394\u2013415. https:\/\/doi.org\/10.1210\/jc.2015-2175","journal-title":"J Clin Endocrinol Metab"},{"key":"4743_CR12","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1097\/MPG.0b013e31823e9412","volume":"54","author":"W H\u00f6gler","year":"2012","unstructured":"H\u00f6gler W, Baumann U, Kelly D (2012) Endocrine and bone metabolic complications in chronic liver disease and after liver transplantation in children. J Pediatr Gastroenterol Nutr 54:313\u2013321. https:\/\/doi.org\/10.1097\/MPG.0b013e31823e9412","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"4743_CR13","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1016\/j.ecl.2017.07.005","volume":"46","author":"IR Reid","year":"2017","unstructured":"Reid IR (2017) Vitamin D effect on bone mineral density and fractures. Endocrinol Metab Clin North Am 46:935\u2013945. https:\/\/doi.org\/10.1016\/j.ecl.2017.07.005","journal-title":"Endocrinol Metab Clin North Am"},{"key":"4743_CR14","doi-asserted-by":"publisher","first-page":"1258","DOI":"10.1007\/s00198-006-0114-1","volume":"17","author":"RM Daly","year":"2006","unstructured":"Daly RM, Bass SL (2006) Lifetime sport and leisure activity participation is associated with greater bone size, quality and strength in older men. Osteoporos Int 17:1258\u20131267. https:\/\/doi.org\/10.1007\/s00198-006-0114-1","journal-title":"Osteoporos Int"},{"key":"4743_CR15","doi-asserted-by":"publisher","first-page":"120","DOI":"10.5152\/tftrd.2015.81905","volume":"61","author":"Y Sayar","year":"2015","unstructured":"Sayar Y, Arikan FI, Tasar MA, Dallar Y (2015) Effect of sportive activity on bone mineral density during adolescence. T\u00fcrk Fiz Tip Rehab Derg 61:120\u2013124. https:\/\/doi.org\/10.5152\/tftrd.2015.81905","journal-title":"T\u00fcrk Fiz Tip Rehab Derg"},{"key":"4743_CR16","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1111\/apa.13052","volume":"104","author":"G Dubnov-Raz","year":"2015","unstructured":"Dubnov-Raz G, Azar M, Reuveny R, Katz U, Weintraub M, Constantini NW (2015) Changes in fitness are associated with changes in body composition and bone health in children after cancer. Acta Paediatr 104:1055\u20131061. https:\/\/doi.org\/10.1111\/apa.13052","journal-title":"Acta Paediatr"},{"key":"4743_CR17","doi-asserted-by":"publisher","first-page":"e670","DOI":"10.1542\/peds.2009-0292","volume":"125","author":"JP Hough","year":"2010","unstructured":"Hough JP, Boyd RN, Keating JL (2010) Systematic review of interventions for low bone mineral density in children with cerebral palsy. Pediatrics 125:e670-678. https:\/\/doi.org\/10.1542\/peds.2009-0292","journal-title":"Pediatrics"},{"key":"4743_CR18","first-page":"445","volume":"14","author":"H Hoyer-Kuhn","year":"2014","unstructured":"Hoyer-Kuhn H, Semler O, Stark C, Struebing N, Goebel O, Schoenau E (2014) A specialized rehabilitation approach improves mobility in children with osteogenesis imperfecta. J Musculoskelet Neuronal Interact 14:445\u2013453","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"4743_CR19","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1177\/0269215507080763","volume":"22","author":"O Semler","year":"2008","unstructured":"Semler O, Fricke O, Vezyroglou K, Stark C, Stabrey A, Schoenau E (2008) Results of a prospective pilot trial on mobility after whole body vibration in children and adolescents with osteogenesis imperfecta. Clin Rehabil 22:387\u2013394. https:\/\/doi.org\/10.1177\/0269215507080763","journal-title":"Clin Rehabil"},{"key":"4743_CR20","doi-asserted-by":"publisher","first-page":"2734","DOI":"10.1210\/jc.2017-00275","volume":"102","author":"W Hogler","year":"2017","unstructured":"Hogler W, Scott J, Bishop N, Arundel P, Nightingale P, Mughal MZ, Padidela R, Shaw N, Crabtree N (2017) The effect of whole body vibration training on bone and muscle function in children with osteogenesis imperfecta. J Clin Endocrinol Metab 102:2734\u20132743. https:\/\/doi.org\/10.1210\/jc.2017-00275","journal-title":"J Clin Endocrinol Metab"},{"key":"4743_CR21","doi-asserted-by":"publisher","first-page":"S341","DOI":"10.1002\/central\/CN-01064425\/full?contentLanguage=en","volume":"28","author":"ML Bianchi","year":"2013","unstructured":"Bianchi ML, Vai S, Morandi L, Baranello G, Pasanisi B, Rubin C (2013) Effects of low-magnitude high-frequency vibration on bone density, bone resorption and muscular strength in ambulant children affected by duchenne muscular dystrophy. J Bone Miner Res 28:S341. https:\/\/doi.org\/10.1002\/central\/CN-01064425\/full?contentLanguage=en","journal-title":"J Bone Miner Res"},{"key":"4743_CR22","first-page":"13","volume":"13","author":"AC S\u00f6derpalm","year":"2013","unstructured":"S\u00f6derpalm AC, Kroksmark AK, Magnusson P, Karlsson J, Tulinius M, Swolin-Eide D (2013) Whole body vibration therapy in patients with Duchenne muscular dystrophy \u2212 A prospective observational study. J Musculoskelet Neuronal Interact 13:13\u201318","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"4743_CR23","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1002\/mus.25431","volume":"55","author":"A Petryk","year":"2017","unstructured":"Petryk A, Polgreen LE, Grames M, Lowe DA, Hodges JS, Karachunski P (2017) Feasibility and tolerability of whole-body, low-intensity vibration and its effects on muscle function and bone in patients with dystrophinopathies: a pilot study. Muscle Nerve 55:875\u2013883. https:\/\/doi.org\/10.1002\/mus.25431","journal-title":"Muscle Nerve"},{"key":"4743_CR24","first-page":"77","volume":"10","author":"J Ruck","year":"2010","unstructured":"Ruck J, Chabot G, Rauch F (2010) Vibration treatment in cerebral palsy: a randomized controlled pilot study. J Musculoskelet Neuronal Interact 10:77\u201383","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"4743_CR25","first-page":"137","volume":"15","author":"M Saquetto","year":"2015","unstructured":"Saquetto M, Carvalho V, Silva C, Concei\u00e7\u00e3o C, Gomes-Neto M (2015) The effects of whole body vibration on mobility and balance in children with cerebral palsy: a systematic review with meta-analysis. J Musculoskelet Neuronal Interact 15:137\u2013144","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"4743_CR26","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1177\/0031512521991095","volume":"128","author":"F Tekin","year":"2021","unstructured":"Tekin F, Kavlak E (2021) Short and long-term effects of whole-body vibration on spasticity and motor performance in children with hemiparetic cerebral palsy. Percept Mot Skills 128:1107\u20131129. https:\/\/doi.org\/10.1177\/0031512521991095","journal-title":"Percept Mot Skills"},{"key":"4743_CR27","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1589\/jpts.28.7","volume":"28","author":"T Tupimai","year":"2016","unstructured":"Tupimai T, Peungsuwan P, Prasertnoo J, Yamauchi J (2016) Effect of combining passive muscle stretching and whole body vibration on spasticity and physical performance of children and adolescents with cerebral palsy. J Phys Ther Sci 28:7\u201313. https:\/\/doi.org\/10.1589\/jpts.28.7","journal-title":"J Phys Ther Sci"},{"key":"4743_CR28","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1007\/s11914-020-00608-0","volume":"18","author":"D Swolin-Eide","year":"2020","unstructured":"Swolin-Eide D, Magnusson P (2020) Does whole-body vibration treatment make children\u2019s bones stronger? Curr Osteoporos Rep 18:471\u2013479. https:\/\/doi.org\/10.1007\/s11914-020-00608-0","journal-title":"Curr Osteoporos Rep"},{"key":"4743_CR29","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s12969-020-0411-9","volume":"18","author":"R Galindo-Zavala","year":"2020","unstructured":"Galindo-Zavala R, Bou-Torrent R, Magallares-Lopez B, Mir-Perello C, Palmou-Fontana N, Sevilla-Perez B, Medrano-San Ildefonso M, Gonzalez-Fernandez MI, Roman-Pascual A, Alcaniz-Rodriguez P, Nieto-Gonzalez JC, Lopez-Corbeto M, Grana-Gil J (2020) Expert panel consensus recommendations for diagnosis and treatment of secondary osteoporosis in children. Pediatr Rheumatol Online J 18:20. https:\/\/doi.org\/10.1186\/s12969-020-0411-9","journal-title":"Pediatr Rheumatol Online J"},{"key":"4743_CR30","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1159\/000508290","volume":"93","author":"SL Lee","year":"2020","unstructured":"Lee SL, Lim A, Munns C, Simm PJ, Zacharin M (2020) Effect of testosterone treatment for delayed puberty in Duchenne muscular dystrophy. Horm Res Paediatr 93:108\u2013118. https:\/\/doi.org\/10.1159\/000508290","journal-title":"Horm Res Paediatr"},{"key":"4743_CR31","doi-asserted-by":"publisher","first-page":"180","DOI":"10.3389\/fendo.2019.00180","volume":"10","author":"T Michigami","year":"2019","unstructured":"Michigami T, Ozono K (2019) Roles of phosphate in skeleton. Front Endocrinol (Lausanne) 10:180. https:\/\/doi.org\/10.3389\/fendo.2019.00180","journal-title":"Front Endocrinol (Lausanne)"},{"key":"4743_CR32","doi-asserted-by":"publisher","unstructured":"Iolascon G, Moretti A (2022) The rationale for using neridronate in musculoskeletal disorders: from metabolic bone diseases to musculoskeletal pain. Int J Mol Sci 23 https:\/\/doi.org\/10.3390\/ijms23136921","DOI":"10.3390\/ijms23136921"},{"key":"4743_CR33","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.1056\/NEJMc062792","volume":"356","author":"SE Papapoulos","year":"2007","unstructured":"Papapoulos SE, Cremers SC (2007) Prolonged bisphosphonate release after treatment in children. N Engl J Med 356:1075\u20131076. https:\/\/doi.org\/10.1056\/NEJMc062792","journal-title":"N Engl J Med"},{"key":"4743_CR34","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1111\/jpc.13768","volume":"54","author":"Simm PJ, Biggin A, Zacharin MR, Rodda CP, Tham E, Siafarikas A, Jefferies C, Hofman PL, Jensen DE, Woodhead H, Brown J, Wheeler BJ, Brookes D, Lafferty A, Munns CF, Group ABMW","year":"2018","unstructured":"Simm PJ, Biggin A, Zacharin MR, Rodda CP, Tham E, Siafarikas A, Jefferies C, Hofman PL, Jensen DE, Woodhead H, Brown J, Wheeler BJ, Brookes D, Lafferty A, Munns CF, Group ABMW (2018) Consensus guidelines on the use of bisphosphonate therapy in children and adolescents. J Paediatr Child Health 54:223\u2013233. https:\/\/doi.org\/10.1111\/jpc.13768","journal-title":"J Paediatr Child Health"},{"key":"4743_CR35","doi-asserted-by":"publisher","first-page":"1424","DOI":"10.1016\/s0140-6736(13)61091-0","volume":"382","author":"N Bishop","year":"2013","unstructured":"Bishop N, Adami S, Ahmed SF, Ant\u00f3n J, Arundel P, Burren CP, Devogelaer JP, Hangartner T, Hossz\u00fa E, Lane JM, Lorenc R, M\u00e4kitie O, Munns CF, Paredes A, Pavlov H, Plotkin H, Raggio CL, Reyes ML, Schoenau E, Semler O, Sillence DO, Steiner RD (2013) Risedronate in children with osteogenesis imperfecta: a randomised, double-blind, placebo-controlled trial. Lancet 382:1424\u20131432. https:\/\/doi.org\/10.1016\/s0140-6736(13)61091-0","journal-title":"Lancet"},{"key":"4743_CR36","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1016\/j.jpeds.2004.06.066","volume":"145","author":"W H\u00f6gler","year":"2004","unstructured":"H\u00f6gler W, Yap F, Little D, Ambler G, McQuade M, Cowell CT (2004) Short-term safety assessment in the use of intravenous zoledronic acid in children. J Pediatr 145:701\u2013704. https:\/\/doi.org\/10.1016\/j.jpeds.2004.06.066","journal-title":"J Pediatr"},{"key":"4743_CR37","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.bone.2004.03.008","volume":"35","author":"CF Munns","year":"2004","unstructured":"Munns CF, Rauch F, Mier RJ, Glorieux FH (2004) Respiratory distress with pamidronate treatment in infants with severe osteogenesis imperfecta. Bone 35:231\u2013234. https:\/\/doi.org\/10.1016\/j.bone.2004.03.008","journal-title":"Bone"},{"key":"4743_CR38","doi-asserted-by":"publisher","unstructured":"Ward L, Tricco AC, Phuong P, Cranney A, Barrowman N, Gaboury I, Rauch F, Tugwell P, Moher D (2007) Bisphosphonate therapy for children and adolescents with secondary osteoporosis. Cochrane Database Syst Rev:CD005324. https:\/\/doi.org\/10.1002\/14651858.CD005324.pub2","DOI":"10.1002\/14651858.CD005324.pub2"},{"key":"4743_CR39","doi-asserted-by":"publisher","first-page":"1779","DOI":"10.1359\/jbmr.040814","volume":"19","author":"CF Munns","year":"2004","unstructured":"Munns CF, Rauch F, Zeitlin L, Fassier F, Glorieux FH (2004) Delayed osteotomy but not fracture healing in pediatric osteogenesis imperfecta patients receiving pamidronate. Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research 19:1779\u20131786. https:\/\/doi.org\/10.1359\/jbmr.040814","journal-title":"Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research"},{"key":"4743_CR40","doi-asserted-by":"publisher","first-page":"1362","DOI":"10.1002\/jbmr.2486","volume":"30","author":"EA Anam","year":"2015","unstructured":"Anam EA, Rauch F, Glorieux FH, Fassier F, Hamdy R (2015) Osteotomy healing in children with osteogenesis imperfecta receiving bisphosphonate treatment. Journal of bone and mineral research\u202f: the official journal of the American Society for Bone and Mineral Research 30:1362\u20131368. https:\/\/doi.org\/10.1002\/jbmr.2486","journal-title":"Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research"},{"key":"4743_CR41","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1016\/j.bone.2006.04.004","volume":"39","author":"C Land","year":"2006","unstructured":"Land C, Rauch F, Munns CF, Sahebjam S, Glorieux FH (2006) Vertebral morphometry in children and adolescents with osteogenesis imperfecta: effect of intravenous pamidronate treatment. Bone 39:901\u2013906. https:\/\/doi.org\/10.1016\/j.bone.2006.04.004","journal-title":"Bone"},{"key":"4743_CR42","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1016\/j.jpeds.2005.10.041","volume":"148","author":"C Land","year":"2006","unstructured":"Land C, Rauch F, Montpetit K, Ruck-Gibis J, Glorieux FH (2006) Effect of intravenous pamidronate therapy on functional abilities and level of ambulation in children with osteogenesis imperfecta. J Pediatr 148:456\u2013460. https:\/\/doi.org\/10.1016\/j.jpeds.2005.10.041","journal-title":"J Pediatr"},{"key":"4743_CR43","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1210\/jc.2005-2413","volume":"91","author":"F Rauch","year":"2006","unstructured":"Rauch F, Munns C, Land C, Glorieux FH (2006) Pamidronate in children and adolescents with osteogenesis imperfecta: effect of treatment discontinuation. J Clin Endocrinol Metab 91:1268\u20131274. https:\/\/doi.org\/10.1210\/jc.2005-2413","journal-title":"J Clin Endocrinol Metab"},{"key":"4743_CR44","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1210\/jc.2005-2036","volume":"91","author":"F Rauch","year":"2006","unstructured":"Rauch F, Travers R, Glorieux FH (2006) Pamidronate in children with osteogenesis imperfecta: histomorphometric effects of long-term therapy. J Clin Endocrinol Metab 91:511\u2013516. https:\/\/doi.org\/10.1210\/jc.2005-2036","journal-title":"J Clin Endocrinol Metab"},{"key":"4743_CR45","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1016\/s0140-6736(04)16101-1","volume":"363","author":"R Sakkers","year":"2004","unstructured":"Sakkers R, Kok D, Engelbert R, van Dongen A, Jansen M, Pruijs H, Verbout A, Schweitzer D, Uiterwaal C (2004) Skeletal effects and functional outcome with olpadronate in children with osteogenesis imperfecta: a 2-year randomised placebo-controlled study. Lancet 363:1427\u20131431. https:\/\/doi.org\/10.1016\/s0140-6736(04)16101-1","journal-title":"Lancet"},{"key":"4743_CR46","doi-asserted-by":"publisher","first-page":"1293","DOI":"10.1172\/jci200215952","volume":"110","author":"F Rauch","year":"2002","unstructured":"Rauch F, Travers R, Plotkin H, Glorieux FH (2002) The effects of intravenous pamidronate on the bone tissue of children and adolescents with osteogenesis imperfecta. J Clin Investig 110:1293\u20131299. https:\/\/doi.org\/10.1172\/jci200215952","journal-title":"J Clin Investig"},{"key":"4743_CR47","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1056\/NEJM199810013391402","volume":"339","author":"FH Glorieux","year":"1998","unstructured":"Glorieux FH, Bishop NJ, Plotkin H, Chabot G, Lanoue G, Travers R (1998) Cyclic administration of pamidronate in children with severe osteogenesis imperfecta. N Engl J Med 339:947\u2013952","journal-title":"N Engl J Med"},{"key":"4743_CR48","first-page":"1846","volume":"85","author":"H Plotkin","year":"2000","unstructured":"Plotkin H, Rauch F, Bishop NJ, Montpetit K, Ruck-Gibis J, Travers R, Glorieux FH (2000) Pamidronate treatment of severe osteogenesis imperfecta in children under 3 years of age. J Clin Endocrinol Metab 85:1846\u20131850","journal-title":"J Clin Endocrinol Metab"},{"key":"4743_CR49","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.1515\/jpem-2014-0527","volume":"28","author":"MJ Kim","year":"2015","unstructured":"Kim MJ, Kim SN, Lee IS, Chung S, Lee J, Yang Y, Lee I, Koh SE (2015) Effects of bisphosphonates to treat osteoporosis in children with cerebral palsy: a meta-analysis. J Pediatr Endocrinol Metab 28:1343\u20131350. https:\/\/doi.org\/10.1515\/jpem-2014-0527","journal-title":"J Pediatr Endocrinol Metab"},{"key":"4743_CR50","doi-asserted-by":"publisher","first-page":"2703","DOI":"10.1007\/s00198-012-1911-3","volume":"23","author":"AM Sbrocchi","year":"2012","unstructured":"Sbrocchi AM, Rauch F, Jacob P, McCormick A, McMillan HJ, Matzinger MA, Ward LM (2012) The use of intravenous bisphosphonate therapy to treat vertebral fractures due to osteoporosis among boys with Duchenne muscular dystrophy. Osteoporos Int 23:2703\u20132711. https:\/\/doi.org\/10.1007\/s00198-012-1911-3","journal-title":"Osteoporos Int"},{"key":"4743_CR51","doi-asserted-by":"publisher","first-page":"e5222","DOI":"10.1210\/clinem\/dgab458","volume":"106","author":"LM Ward","year":"2021","unstructured":"Ward LM, Choudhury A, Alos N, Cabral DA, Rodd C, Sbrocchi AM, Taback S, Padidela R, Shaw NJ, Hosszu E, Kostik M, Alexeeva E, Thandrayen K, Shenouda N, Jaremko JL, Sunkara G, Sayyed S, Aftring RP, Munns CF (2021) Zoledronic acid vs placebo in pediatric glucocorticoid-induced osteoporosis: a randomized, double-blind, phase 3 trial. J Clin Endocrinol Metab 106:e5222\u2013e5235. https:\/\/doi.org\/10.1210\/clinem\/dgab458","journal-title":"J Clin Endocrinol Metab"},{"key":"4743_CR52","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1007\/s11914-017-0380-1","volume":"15","author":"AM Boyce","year":"2017","unstructured":"Boyce AM (2017) Denosumab: an emerging therapy in pediatric bone disorders. Curr Osteoporos Rep 15:283\u2013292. https:\/\/doi.org\/10.1007\/s11914-017-0380-1","journal-title":"Curr Osteoporos Rep"},{"key":"4743_CR53","unstructured":"ClinicalTrials.gov (2022) Open-label extension denosumab study in children and young adults with osteogenesis imperfecta. ClinicalTrials.gov Identifier: NCT03638128."},{"key":"4743_CR54","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1210\/jc.2013-3081","volume":"99","author":"HD Wang","year":"2014","unstructured":"Wang HD, Boyce AM, Tsai JY, Gafni RI, Farley FA, Kasa-Vubu JZ, Molinolo AA, Collins MT (2014) Effects of denosumab treatment and discontinuation on human growth plates. J Clin Endocrinol Metab 99:891\u2013897. https:\/\/doi.org\/10.1210\/jc.2013-3081","journal-title":"J Clin Endocrinol Metab"},{"key":"4743_CR55","doi-asserted-by":"publisher","unstructured":"Kobayashi E, Setsu N (2015) Osteosclerosis induced by denosumab. The Lancet 385.\u00a0https:\/\/doi.org\/10.1016\/s0140-6736(14)61338-6","DOI":"10.1016\/s0140-6736(14)61338-6"},{"key":"4743_CR56","doi-asserted-by":"publisher","first-page":"3954","DOI":"10.1210\/jc.2014-3072","volume":"99","author":"H Hoyer-Kuhn","year":"2014","unstructured":"Hoyer-Kuhn H, Semler O, Schoenau E (2014) Effect of denosumab on the growing skeleton in osteogenesis imperfecta. J Clin Endocrinol Metab 99:3954\u20133955. https:\/\/doi.org\/10.1210\/jc.2014-3072","journal-title":"J Clin Endocrinol Metab"},{"key":"4743_CR57","first-page":"24","volume":"16","author":"H Hoyer-Kuhn","year":"2016","unstructured":"Hoyer-Kuhn H, Franklin J, Allo G, Kron M, Netzer C, Eysel P, Hero B, Schoenau E, Semler O (2016) Safety and efficacy of denosumab in children with osteogenesis imperfecta - a first prospective trial. J Musculoskelet Neuronal Interact 16:24\u201332","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"4743_CR58","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13023-014-0145-1","volume":"9","author":"H Hoyer-Kuhn","year":"2014","unstructured":"Hoyer-Kuhn H, Netzer C, Koerber F, Schoenau E, Semler O (2014) Two years\u2019 experience with denosumab for children with Osteogenesis imperfecta type VI. Orphanet J Rare Dis 9:1\u20138. https:\/\/doi.org\/10.1186\/s13023-014-0145-1","journal-title":"Orphanet J Rare Dis"},{"key":"4743_CR59","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1210\/jc.2017-02025","volume":"103","author":"S Uday","year":"2018","unstructured":"Uday S, Gaston CL, Rogers L, Parry M, Joffe J, Pearson J, Sutton D, Grimer R, H\u00f6gler W (2018) Osteonecrosis of the jaw and rebound hypercalcemia in young people treated with denosumab for giant cell tumor of bone. J Clin Endocrinol Metab 103:596\u2013603. https:\/\/doi.org\/10.1210\/jc.2017-02025","journal-title":"J Clin Endocrinol Metab"},{"key":"4743_CR60","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1111\/scd.12588","volume":"41","author":"B Mariz","year":"2021","unstructured":"Mariz B, Migliorati CA, Alves FA, Penteado FM, Carvalho NPF, Santos-Silva AR, Rocha AC (2021) Successful denosumab treatment for central giant cell granuloma in a 9-year-old child. Spec Care Dentist 41:519\u2013525. https:\/\/doi.org\/10.1111\/scd.12588","journal-title":"Spec Care Dentist"},{"key":"4743_CR61","doi-asserted-by":"publisher","DOI":"10.1016\/j.bonr.2021.101148","volume":"15","author":"K Horiuchi","year":"2021","unstructured":"Horiuchi K, Kobayashi E, Mizuno T, Susa M, Chiba K (2021) Hypercalcemia following discontinuation of denosumab therapy: a systematic review. Bone Rep 15:101148. https:\/\/doi.org\/10.1016\/j.bonr.2021.101148","journal-title":"Bone Rep"},{"key":"4743_CR62","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1007\/s00774-015-0677-z","volume":"34","author":"N Setsu","year":"2016","unstructured":"Setsu N, Kobayashi E, Asano N, Yasui N, Kawamoto H, Kawai A, Horiuchi K (2016) Severe hypercalcemia following denosumab treatment in a juvenile patient. J Bone Miner Metab 34:118\u2013122. https:\/\/doi.org\/10.1007\/s00774-015-0677-z","journal-title":"J Bone Miner Metab"},{"key":"4743_CR63","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1002\/pbc.25393","volume":"62","author":"N Gossai","year":"2015","unstructured":"Gossai N, Hilgers MV, Polgreen LE, Greengard EG (2015) Critical hypercalcemia following discontinuation of denosumab therapy for metastatic giant cell tumor of bone. Pediatr Blood Cancer 62:1078\u20131080. https:\/\/doi.org\/10.1002\/pbc.25393","journal-title":"Pediatr Blood Cancer"},{"key":"4743_CR64","doi-asserted-by":"publisher","first-page":"8854441","DOI":"10.1155\/2020\/8854441","volume":"2020","author":"M Harcus","year":"2020","unstructured":"Harcus M, Aldridge S, Abudu A, Jeys L, Senniappan S, Morgan H, Pizer B (2020) The efficacy of denosumab in the management of a tibial paediatric aneurysmal bone cyst compromised by rebound hypercalcaemia. Case Rep Pediatr 2020:8854441. https:\/\/doi.org\/10.1155\/2020\/8854441","journal-title":"Case Rep Pediatr"},{"key":"4743_CR65","doi-asserted-by":"publisher","unstructured":"Kurucu N, Akyuz C, Ergen FB, Yalcin B, Kosemehmetoglu K, Ayvaz M, Varan A, Aydin B, Kutluk T (2018) Denosumab treatment in aneurysmal bone cyst: evaluation of nine cases. Pediatr Blood Cancer 65.\u00a0https:\/\/doi.org\/10.1002\/pbc.26926","DOI":"10.1002\/pbc.26926"},{"key":"4743_CR66","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1186\/s12891-019-2855-y","volume":"20","author":"HR D\u00fcrr","year":"2019","unstructured":"D\u00fcrr HR, Grahneis F, Baur-Melnyk A, Kn\u00f6sel T, Birkenmaier C, Jansson V, Klein A (2019) Aneurysmal bone cyst: results of an off label treatment with Denosumab. BMC Musculoskelet Disord 20:456. https:\/\/doi.org\/10.1186\/s12891-019-2855-y","journal-title":"BMC Musculoskelet Disord"},{"key":"4743_CR67","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1007\/s10354-020-00810-w","volume":"171","author":"R Kocijan","year":"2021","unstructured":"Kocijan R, Haschka J, Feurstein J, Zwerina J (2021) New therapeutic options for bone diseases. Wien Med Wochenschr 171:120\u2013125. https:\/\/doi.org\/10.1007\/s10354-020-00810-w","journal-title":"Wien Med Wochenschr"},{"key":"4743_CR68","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.1056\/NEJMoa1607948","volume":"375","author":"F Cosman","year":"2016","unstructured":"Cosman F, Crittenden DB, Adachi JD, Binkley N, Czerwinski E, Ferrari S, Hofbauer LC, Lau E, Lewiecki EM, Miyauchi A, Zerbini CA, Milmont CE, Chen L, Maddox J, Meisner PD, Libanati C, Grauer A (2016) Romosozumab treatment in postmenopausal women with osteoporosis. N Engl J Med 375:1532\u20131543. https:\/\/doi.org\/10.1056\/NEJMoa1607948","journal-title":"N Engl J Med"},{"key":"4743_CR69","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1056\/NEJMoa1708322","volume":"377","author":"KG Saag","year":"2017","unstructured":"Saag KG, Petersen J, Brandi ML, Karaplis AC, Lorentzon M, Thomas T, Maddox J, Fan M, Meisner PD, Grauer A (2017) Romosozumab or alendronate for fracture prevention in women with osteoporosis. N Engl J Med 377:1417\u20131427. https:\/\/doi.org\/10.1056\/NEJMoa1708322","journal-title":"N Engl J Med"},{"key":"4743_CR70","unstructured":"ClinicalTrials.gov Identifier: NCT04545554 (2020) Study to evaluate romosozumab in children and adolescents with osteogenesis imperfecta."},{"key":"4743_CR71","unstructured":"ClinicalTrials.gov Identifier: NCT05125809 (2021) Study to assess the efficacy and safety of setrusumab in participants with osteogenesis imperfecta."},{"key":"4743_CR72","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1007\/s11914-021-00665-z","volume":"19","author":"FR Fassier","year":"2021","unstructured":"Fassier FR (2021) Osteogenesis imperfecta-who needs rodding surgery? Curr Osteoporos Rep 19:264\u2013270. https:\/\/doi.org\/10.1007\/s11914-021-00665-z","journal-title":"Curr Osteoporos Rep"},{"key":"4743_CR73","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1097\/BPO.0000000000000724","volume":"38","author":"E Ashby","year":"2016","unstructured":"Ashby E, Montpetit K, Hamdy RC, Fassier F (2016) Functional outcome of forearm rodding in children with osteogenesis imperfecta. J Pediatr Orthop 38:54\u201359. https:\/\/doi.org\/10.1097\/BPO.0000000000000724","journal-title":"J Pediatr Orthop"},{"key":"4743_CR74","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1080\/17453674.2021.1941628","volume":"92","author":"RJ Sakkers","year":"2021","unstructured":"Sakkers RJ, Montpetit K, Tsimicalis A, Wirth T, Verhoef M, Hamdy R, Ouellet JA, Castelein RM, Damas C, Janus GJ, Nijhuis WH, Panzeri L, Paveri S, Mekking D, Thorstad K, Kruse RW (2021) A roadmap to surgery in osteogenesis imperfecta: results of an international collaboration of patient organizations and interdisciplinary care teams. Acta Orthop 92:608\u2013614. https:\/\/doi.org\/10.1080\/17453674.2021.1941628","journal-title":"Acta Orthop"},{"key":"4743_CR75","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/j.jocd.2014.01.004","volume":"17","author":"Bishop N, Arundel P, Clark E, Dimitri P, Farr J, Jones G, Makitie O, Munns CF, Shaw N, International Society of Clinical D","year":"2014","unstructured":"Bishop N, Arundel P, Clark E, Dimitri P, Farr J, Jones G, Makitie O, Munns CF, Shaw N, International Society of Clinical D (2014) Fracture prediction and the definition of osteoporosis in children and adolescents: the ISCD 2013 Pediatric Official Positions. J Clin Densitom 17:275\u2013280. https:\/\/doi.org\/10.1016\/j.jocd.2014.01.004","journal-title":"J Clin Densitom"},{"key":"4743_CR76","doi-asserted-by":"publisher","unstructured":"Ward LM, Weber DR, Munns CF, Hogler W, Zemel BS (2020) A contemporary view of the definition and diagnosis of osteoporosis in children and adolescents. J Clin Endocrinol Metab 105:e2088\u2013e2097.\u00a0https:\/\/doi.org\/10.1210\/clinem\/dgz294","DOI":"10.1210\/clinem\/dgz294"},{"key":"4743_CR77","doi-asserted-by":"publisher","first-page":"3427","DOI":"10.1007\/s00198-016-3723-3","volume":"27","author":"P Trejo","year":"2016","unstructured":"Trejo P, Rauch F (2016) Osteogenesis imperfecta in children and adolescents-new developments in diagnosis and treatment. Osteoporos Int 27:3427\u20133437. https:\/\/doi.org\/10.1007\/s00198-016-3723-3","journal-title":"Osteoporos Int"},{"key":"4743_CR78","doi-asserted-by":"publisher","unstructured":"Dwan K, Phillipi CA, Steiner RD, Basel D (2016) Bisphosphonate therapy for osteogenesis imperfecta. Cochrane Database Syst Rev 10:CD005088. https:\/\/doi.org\/10.1002\/14651858.CD005088.pub4","DOI":"10.1002\/14651858.CD005088.pub4"},{"key":"4743_CR79","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1007\/s00774-013-0438-9","volume":"31","author":"GI Baroncelli","year":"2013","unstructured":"Baroncelli GI, Vierucci F, Bertelloni S, Erba P, Zampollo E, Giuca MR (2013) Pamidronate treatment stimulates the onset of recovery phase reducing fracture rate and skeletal deformities in patients with idiopathic juvenile osteoporosis: comparison with untreated patients. J Bone Miner Metab 31:533\u2013543. https:\/\/doi.org\/10.1007\/s00774-013-0438-9","journal-title":"J Bone Miner Metab"},{"key":"4743_CR80","doi-asserted-by":"publisher","first-page":"1435","DOI":"10.1002\/jbmr.3447","volume":"33","author":"LM Ward","year":"2018","unstructured":"Ward LM, Ma J, Lang B, Ho J, Alos N, Matzinger MA, Shenouda N et al (2018) Bone morbidity and recovery in children with acute lymphoblastic leukemia: results of a six-year prospective cohort study. J Bone Miner Res 33:1435\u20131443. https:\/\/doi.org\/10.1002\/jbmr.3447","journal-title":"J Bone Miner Res"},{"key":"4743_CR81","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/s1474-4422(18)30025-5","volume":"17","author":"DJ Birnkrant","year":"2018","unstructured":"Birnkrant DJ, Bushby K, Bann CM, Alman BA, Apkon SD, Blackwell A, Case LE, Cripe L, Hadjiyannakis S, Olson AK, Sheehan DW, Bolen J, Weber DR, Ward LM (2018) Diagnosis and management of Duchenne muscular dystrophy, part 2: respiratory, cardiac, bone health, and orthopaedic management. The Lancet Neurology 17:347\u2013361. https:\/\/doi.org\/10.1016\/s1474-4422(18)30025-5","journal-title":"The Lancet Neurology"},{"key":"4743_CR82","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/s1474-4422(18)30024-3","volume":"17","author":"DJ Birnkrant","year":"2018","unstructured":"Birnkrant DJ, Bushby K, Bann CM, Apkon SD, Blackwell A, Brumbaugh D, Case LE, Clemens PR, Hadjiyannakis S, Pandya S, Street N, Tomezsko J, Wagner KR, Ward LM, Weber DR (2018) Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and neuromuscular, rehabilitation, endocrine, and gastrointestinal and nutritional management. The Lancet Neurology 17:251\u2013267. https:\/\/doi.org\/10.1016\/s1474-4422(18)30024-3","journal-title":"The Lancet Neurology"},{"key":"4743_CR83","doi-asserted-by":"publisher","unstructured":"Bhardwaj A, Swe KM, Sinha NK, Osunkwo I (2016) Treatment for osteoporosis in people with \u00df-thalassaemia. Cochrane Database Syst Rev 3:Cd010429. https:\/\/doi.org\/10.1002\/14651858.CD010429.pub2","DOI":"10.1002\/14651858.CD010429.pub2"},{"key":"4743_CR84","doi-asserted-by":"publisher","first-page":"576","DOI":"10.3389\/fendo.2020.00576","volume":"11","author":"LM Ward","year":"2020","unstructured":"Ward LM (2020) Glucocorticoid-induced osteoporosis: why kids are different. Front Endocrinol (Lausanne) 11:576. https:\/\/doi.org\/10.3389\/fendo.2020.00576","journal-title":"Front Endocrinol (Lausanne)"},{"key":"4743_CR85","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.nmd.2018.09.005","volume":"29","author":"S Joseph","year":"2019","unstructured":"Joseph S, Wang C, Di Marco M, Horrocks I, Abu-Arafeh I, Baxter A, Cordeiro N, McLellan L, McWilliam K, Naismith K, Stephen E, Ahmed SF, Wong SC (2019) Fractures and bone health monitoring in boys with Duchenne muscular dystrophy managed within the Scottish Muscle Network. Neuromuscul Disord 29:59\u201366. https:\/\/doi.org\/10.1016\/j.nmd.2018.09.005","journal-title":"Neuromuscul Disord"},{"key":"4743_CR86","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1111\/cen.12053","volume":"78","author":"H Gleeson","year":"2013","unstructured":"Gleeson H, Davis J, Jones J, O\u2019Shea E, Clayton PE (2013) The challenge of delivering endocrine care and successful transition to adult services in adolescents with congenital adrenal hyperplasia: experience in a single centre over 18 years. Clin Endocrinol (Oxf) 78:23\u201328. https:\/\/doi.org\/10.1111\/cen.12053","journal-title":"Clin Endocrinol (Oxf)"},{"key":"4743_CR87","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1159\/000343818","volume":"78","author":"A Godbout","year":"2012","unstructured":"Godbout A, Tejedor I, Malivoir S, Polak M, Touraine P (2012) Transition from pediatric to adult healthcare: assessment of specific needs of patients with chronic endocrine conditions. Horm Res Paediatr 78:247\u2013255. https:\/\/doi.org\/10.1159\/000343818","journal-title":"Horm Res Paediatr"},{"key":"4743_CR88","doi-asserted-by":"publisher","unstructured":"Campbell F, Biggs K, Aldiss SK, O'Neill PM, Clowes M, McDonagh J, While A, Gibson F (2016) Transition of care for adolescents from paediatric services to adult health services. Cochrane Database Syst Rev 4:CD009794. https:\/\/doi.org\/10.1002\/14651858.CD009794.pub2","DOI":"10.1002\/14651858.CD009794.pub2"},{"key":"4743_CR89","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1016\/1054-139x(93)90143-d","volume":"14","author":"RW Blum","year":"1993","unstructured":"Blum RW, Garell D, Hodgman CH, Jorissen TW, Okinow NA, Orr DP, Slap GB (1993) Transition from child-centered to adult health-care systems for adolescents with chronic conditions. A position paper of the Society for Adolescent Medicine. J Adolesc Health 14:570\u2013576. https:\/\/doi.org\/10.1016\/1054-139x(93)90143-d","journal-title":"J Adolesc Health"}],"container-title":["European Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-022-04743-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00431-022-04743-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-022-04743-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,4]],"date-time":"2023-02-04T03:33:26Z","timestamp":1675481606000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00431-022-04743-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,6]]},"references-count":89,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,2]]}},"alternative-id":["4743"],"URL":"https:\/\/doi.org\/10.1007\/s00431-022-04743-x","relation":{},"ISSN":["1432-1076"],"issn-type":[{"value":"1432-1076","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,6]]},"assertion":[{"value":"9 November 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 November 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 November 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 December 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}