{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:10:56Z","timestamp":1792782656554,"version":"4.5.0"},"reference-count":64,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2024,3,16]],"date-time":"2024-03-16T00:00:00Z","timestamp":1710547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,3,16]],"date-time":"2024-03-16T00:00:00Z","timestamp":1710547200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"This study was (partially) supported by the Italian Ministry of Health (Ricerca Corrente)."}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"DOI":"10.1007\/s00431-024-05467-w","type":"journal-article","created":{"date-parts":[[2024,3,16]],"date-time":"2024-03-16T02:02:11Z","timestamp":1710554531000},"page":"2625-2636","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Ototoxic and nephrotoxic drugs in neonatal intensive care units: results of a Spanish and Italian survey"],"prefix":"10.1007","volume":"183","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7916-4571","authenticated-orcid":false,"given":"Cristina","family":"Arribas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6650-7881","authenticated-orcid":false,"given":"Nunzia","family":"Decembrino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9175-9394","authenticated-orcid":false,"given":"Genny","family":"Raffaeli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2650-0084","authenticated-orcid":false,"given":"Ilaria","family":"Amodeo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3378-5038","authenticated-orcid":false,"given":"Juan Luis","family":"Gonz\u00e1lez-Caballero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6436-9507","authenticated-orcid":false,"given":"M\u00f3nica","family":"Riaza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Ortiz-Movilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4831-3570","authenticated-orcid":false,"given":"Luca","family":"Massenzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3305-7014","authenticated-orcid":false,"given":"Camilla","family":"Gizzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriella","family":"Araimo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donatella","family":"Cattarelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2634-1498","authenticated-orcid":false,"given":"Salvatore","family":"Aversa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2155-8535","authenticated-orcid":false,"given":"Stefano","family":"Martinelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simonetta","family":"Frezza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Orfeo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6477-0299","authenticated-orcid":false,"given":"Fabio","family":"Mosca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4921-1437","authenticated-orcid":false,"given":"Giacomo","family":"Cavallaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8835-0667","authenticated-orcid":false,"given":"Felipe","family":"Garrido","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"On behalf of the Segurneo Committee of the Spanish Neonatal Society (SENeo), the Neonatal Pharmacotherapy Study Group, the Neonatal Nephrology Study Group, the Sense Organ Study Group of the Italian Society of Neonatology (SIN)","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,16]]},"reference":[{"key":"5467_CR1","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1007\/s00431-019-03556-9","volume":"179","author":"L Schrier","year":"2020","unstructured":"Schrier L, Hadjipanayis A, Stiris T, Ross-Russell RI, Valiulis A, Turner MA, Zhao W, De Cock P, de Wildt SN, Allegaert K, van den Anker J (2020) Off-label use of medicines in neonates, infants, children, and adolescents: a joint policy statement by the European Academy of Paediatrics and the European society for Developmental Perinatal and Pediatric Pharmacology. Eur J Pediatr 179:839\u2013847","journal-title":"Eur J Pediatr"},{"key":"5467_CR2","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1056\/NEJMra035092","volume":"349","author":"GL Kearns","year":"2003","unstructured":"Kearns GL, Abdel-Rahman SM, Alander SW, Blowey DL, Leeder JS, Kauffman RE (2003) Developmental pharmacology\u2013drug disposition, action, and therapy in infants and children. N Engl J Med 349:1157\u20131167","journal-title":"N Engl J Med"},{"key":"5467_CR3","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1179\/acb.2008.003","volume":"63","author":"K Allegaert","year":"2008","unstructured":"Allegaert K, Verbesselt R, Naulaers G, Van den Anker J, Rayyan M, Debeer A, de Hoon J (2008) Developmental pharmacology: neonates are not just small adults\u2026. Acta Clin Belg 63:16\u201324","journal-title":"Acta Clin Belg"},{"key":"5467_CR4","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1111\/pan.12176","volume":"24","author":"K Allegaert","year":"2014","unstructured":"Allegaert K, Van De Velde M, van den Anker J (2014) Neonatal clinical pharmacology. Pediatr Anesthesia 24:30\u201338","journal-title":"Pediatr Anesthesia"},{"key":"5467_CR5","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1159\/000360648","volume":"105","author":"K Allegaert","year":"2014","unstructured":"Allegaert K, van den Anker JN (2014) Clinical pharmacology in neonates: small size, huge variability. Neonatology 105:344\u2013349","journal-title":"Neonatology"},{"key":"5467_CR6","doi-asserted-by":"publisher","first-page":"101327","DOI":"10.1016\/j.siny.2022.101327","volume":"27","author":"K Allegaert","year":"2022","unstructured":"Allegaert K, van den Anker JN (2022) From immature pharmacotherapy towards pharmacotherapy of the immature. Semin Fetal Neonatal Med. Elsevier 27:101327","journal-title":"Semin Fetal Neonatal Med. Elsevier"},{"issue":"Suppl 10","key":"5467_CR7","first-page":"S10","volume":"58","author":"J van den Anker","year":"2018","unstructured":"van den Anker J, Reed MD, Allegaert K, Kearns GL (2018) Developmental Changes in Pharmacokinetics and Pharmacodynamics. J Clin Pharmacol 58(Suppl 10):S10\u2013S25","journal-title":"J Clin Pharmacol"},{"key":"5467_CR8","doi-asserted-by":"publisher","first-page":"14","DOI":"10.3390\/jpm7040014","volume":"7","author":"I Aka","year":"2017","unstructured":"Aka I, Bernal CJ, Carroll R, Maxwell-Horn A, Oshikoya KA, Van Driest SL (2017) Clinical pharmacogenetics of cytochrome P450-associated drugs in children. J Personalized Med 7:14","journal-title":"J Personalized Med"},{"key":"5467_CR9","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.3390\/antibiotics10101182","volume":"10","author":"M Gijsen","year":"2021","unstructured":"Gijsen M, Vlasselaers D, Spriet I, Allegaert K (2021) Pharmacokinetics of Antibiotics in Pediatric Intensive Care: Fostering Variability to Attain Precision Medicine. Antibiotics (Basel) 10:1182","journal-title":"Antibiotics (Basel)"},{"key":"5467_CR10","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1001\/jamapediatrics.2022.0187","volume":"176","author":"JH McDermott","year":"2022","unstructured":"McDermott JH, Mahaveer A, James RA, Booth N, Turner M, Harvey KE, Miele G et al (2022) Rapid Point-of-Care Genotyping to Avoid Aminoglycoside-Induced Ototoxicity in Neonatal Intensive Care. JAMA Pediatr 176:486\u2013492","journal-title":"JAMA Pediatr"},{"key":"5467_CR11","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1002\/cpt.603","volume":"101","author":"C Lanvers-Kaminsky","year":"2017","unstructured":"Lanvers-Kaminsky C, Aa Z-D, Parfitt R, Ciarimboli G (2017) Drug-induced ototoxicity: Mechanisms, Pharmacogenetics, and protective strategies. Clin Pharmacol Ther 101:491\u2013500","journal-title":"Clin Pharmacol Ther"},{"key":"5467_CR12","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1002\/cpt.2910","volume":"114","author":"R Rigobello","year":"2023","unstructured":"Rigobello R, Shaw J, Ilg D, Zimmerman R, Edelmann L, Kornreich R, Scott SA, Cody N (2023) Clinical Pharmacogenomic MT-RNR1 Screening for Aminoglycoside-Induced Ototoxicity and the Post-Test Counseling Conundrum. Clin Pharmacol Ther 114:262\u2013265","journal-title":"Clin Pharmacol Ther"},{"key":"5467_CR13","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1002\/cpt.2309","volume":"111","author":"JH McDermott","year":"2022","unstructured":"McDermott JH, Wolf J, Hoshitsuki K, Huddart R, Caudle KE, Whirl-Carrillo M, Steyger PS, Smith RJH, Cody N, Rodriguez-Antona C, Klein TE, Newman WG (2022) Clinical Pharmacogenetics Implementation Consortium Guideline for the Use of Aminoglycosides Based on MT-RNR1 Genotype. Clin Pharmacol Ther 111:366\u2013372","journal-title":"Clin Pharmacol Ther"},{"key":"5467_CR14","doi-asserted-by":"publisher","first-page":"375","DOI":"10.2174\/1871526519666190617154137","volume":"19","author":"W Leowattana","year":"2019","unstructured":"Leowattana W (2019) Antiviral drugs and acute kidney injury (AKI). Infect Disord Drug Targets 19:375\u2013382","journal-title":"Infect Disord Drug Targets"},{"key":"5467_CR15","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.1016\/j.jpeds.2012.11.069","volume":"162","author":"JM Misurac","year":"2013","unstructured":"Misurac JM, Knoderer CA, Leiser JD, Nailescu C, Wilson AC, Andreoli SP (2013) Nonsteroidal anti-inflammatory drugs are an important cause of acute kidney injury in children. J Pediatr 162:1153-1159. e1151","journal-title":"J Pediatr"},{"key":"5467_CR16","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.pedneo.2022.06.018","volume":"64","author":"JY Ting","year":"2023","unstructured":"Ting JY, McDougal K, De Mello A, Kwan E, Mammen C (2023) Acute kidney injury among preterm infants receiving nonsteroidal anti-inflammatory drugs: A pilot study. Pediatr Neonatol 64:313\u2013318","journal-title":"Pediatr Neonatol"},{"key":"5467_CR17","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1159\/000526267","volume":"147","author":"Z Yousif","year":"2023","unstructured":"Yousif Z, Awdishu L (2023) Drug-induced acute kidney injury risk prediction models. Nephron 147:44\u201347","journal-title":"Nephron"},{"key":"5467_CR18","doi-asserted-by":"publisher","first-page":"e1324","DOI":"10.1542\/peds.2013-0008","volume":"131","author":"C Muse","year":"2013","unstructured":"Joint Committee on Infant Hearing of the American Academy of P, Muse C, Harrison J, Yoshinaga-Itano C, Grimes A, Brookhouser PE, Epstein S, Buchman C, Mehl A, Vohr B, Moeller MP, Martin P, Benedict BS, Scoggins B, Crace J, King M, Sette A, Martin B (2013) Supplement to the JCIH 2007 position statement: principles and guidelines for early intervention after confirmation that a child is deaf or hard of hearing. Pediatrics 131:e1324-1349","journal-title":"Pediatrics"},{"key":"5467_CR19","doi-asserted-by":"publisher","first-page":"898","DOI":"10.1542\/peds.2007-2333","volume":"120","author":"American Academy of Pediatrics JCoIH","year":"2007","unstructured":"American Academy of Pediatrics JCoIH (2007) Year 2007 position statement: Principles and guidelines for early hearing detection and intervention programs. Pediatrics 120:898\u2013921","journal-title":"Pediatrics"},{"key":"5467_CR20","first-page":"2291","volume":"75","author":"J Marissen","year":"2020","unstructured":"Marissen J, Fortmann I, Humberg A, Rausch TK, Simon A, Stein A, Schaible T, Eichhorn J, Wintgens J, Roll C, Heitmann F, Herting E, Gopel W, Hartel C (2020) Vancomycin-induced ototoxicity in very-low-birthweight infants. J Antimicrob Chemother 75:2291\u20132298","journal-title":"J Antimicrob Chemother"},{"key":"5467_CR21","doi-asserted-by":"publisher","first-page":"2856","DOI":"10.1128\/AAC.02139-13","volume":"58","author":"M Cohen-Wolkowiez","year":"2014","unstructured":"Cohen-Wolkowiez M, Watt KM, Zhou C, Bloom BT, Poindexter B, Castro L, Gao J, Capparelli EV, Benjamin DK Jr, Smith PB (2014) Developmental pharmacokinetics of piperacillin and tazobactam using plasma and dried blood spots from infants. Antimicrob Agents Chemother 58:2856\u20132865","journal-title":"Antimicrob Agents Chemother"},{"key":"5467_CR22","doi-asserted-by":"publisher","first-page":"19","DOI":"10.3390\/pharmacy10010019","volume":"10","author":"A Veldman","year":"2022","unstructured":"Veldman A, Richter E, Hacker C, Fischer D (2022) The Use of Off-Label Medications in Newborn Infants Despite an Approved Alternative Being Available-Results of a National Survey. Pharmacy (Basel) 10:19","journal-title":"Pharmacy (Basel)"},{"key":"5467_CR23","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.clp.2011.12.002","volume":"39","author":"PG Johnston","year":"2012","unstructured":"Johnston PG, Gillam-Krakauer M, Fuller MP, Reese J (2012) Evidence-based use of indomethacin and ibuprofen in the neonatal intensive care unit. Clin Perinatol 39:111\u2013136","journal-title":"Clin Perinatol"},{"key":"5467_CR24","first-page":"4099","volume":"4","author":"GM Pacifici","year":"2016","unstructured":"Pacifici GM (2016) The effects and pharmacokinetics of acyclovir in neonates. Int J Pediatr 4:4099\u20134115","journal-title":"Int J Pediatr"},{"key":"5467_CR25","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1542\/peds.108.2.230","volume":"108","author":"DW Kimberlin","year":"2001","unstructured":"Kimberlin DW, Lin C-Y, Jacobs RF, Powell DA, Corey L, Gruber WC, Rathore M, Bradley JS, Diaz PS, Kumar M (2001) Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections. Pediatrics 108:230\u2013238","journal-title":"Pediatrics"},{"key":"5467_CR26","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.clp.2011.12.008","volume":"39","author":"D Testoni","year":"2012","unstructured":"Testoni D, Smith PB, Benjamin DK Jr (2012) The use of antifungal therapy in neonatal intensive care. Clin Perinatol 39:83\u201398","journal-title":"Clin Perinatol"},{"key":"5467_CR27","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1515\/JPM.2008.064","volume":"36","author":"MH Gantenbein","year":"2008","unstructured":"Gantenbein MH, Bauersfeld U, Baenziger O, Frey B, Neuhaus T, Sennhauser F, Bernet V (2008) Side effects of angiotensin converting enzyme inhibitor (captopril) in newborns and young infants. J Perinat Med 36:448\u2013452","journal-title":"J Perinat Med"},{"key":"5467_CR28","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1007\/s00246-016-1496-2","volume":"38","author":"LC Ku","year":"2017","unstructured":"Ku LC, Zimmerman K, Benjamin DK, Clark RH, Hornik CP, Smith PB, Best Pharmaceuticals for Children Act - Pediatric Trials Network Steering C (2017) Safety of Enalapril in Infants Admitted to the Neonatal Intensive Care Unit. Pediatr Cardiol 38:155\u2013161","journal-title":"Pediatr Cardiol"},{"key":"5467_CR29","doi-asserted-by":"publisher","first-page":"2687","DOI":"10.1007\/s00467-021-04921-3","volume":"36","author":"JP Guignard","year":"2021","unstructured":"Guignard JP, Iacobelli S (2021) Use of diuretics in the neonatal period. Pediatr Nephrol 36:2687\u20132695","journal-title":"Pediatr Nephrol"},{"key":"5467_CR30","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.clp.2011.12.007","volume":"39","author":"JL Segar","year":"2012","unstructured":"Segar JL (2012) Neonatal diuretic therapy: furosemide, thiazides, and spironolactone. Clin Perinatol 39:209\u2013220","journal-title":"Clin Perinatol"},{"key":"5467_CR31","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1016\/j.jpeds.2014.04.058","volume":"165","author":"S Menon","year":"2014","unstructured":"Menon S, Kirkendall ES, Nguyen H, Goldstein SL (2014) Acute kidney injury associated with high nephrotoxic medication exposure leads to chronic kidney disease after 6 months. J Pediatr 165:522-527 e522","journal-title":"J Pediatr"},{"key":"5467_CR32","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1016\/j.ccc.2015.06.005","volume":"31","author":"SL Kane-Gill","year":"2015","unstructured":"Kane-Gill SL, Goldstein SL (2015) Drug-Induced Acute Kidney Injury: A Focus on Risk Assessment for Prevention. Crit Care Clin 31:675\u2013684","journal-title":"Crit Care Clin"},{"key":"5467_CR33","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1097\/MCC.0000000000000453","volume":"23","author":"L Awdishu","year":"2017","unstructured":"Awdishu L (2017) Drug-induced kidney disease in the ICU: mechanisms, susceptibility, diagnosis and management strategies. Curr Opin Crit Care 23:484\u2013490","journal-title":"Curr Opin Crit Care"},{"key":"5467_CR34","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1159\/000531916","volume":"147","author":"N Amatullah","year":"2023","unstructured":"Amatullah N, Stottlemyer BA, Zerfas I, Stevens C, Ozrazgat-Baslanti T, Bihorac A, Kane-Gill SL (2023) Challenges in Pharmacovigilance: Variability in the Criteria for Determining Drug-Associated Acute Kidney Injury in Retrospective, Observational Studies. Nephron. 147:725\u2013732","journal-title":"Nephron."},{"key":"5467_CR35","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1542\/peds.2010-1275","volume":"126","author":"JS Gerber","year":"2010","unstructured":"Gerber JS, Newland JG, Coffin SE, Hall M, Thurm C, Prasad PA, Feudtner C, Zaoutis TE (2010) Variability in antibiotic use at children\u2019s hospitals. Pediatrics 126:1067\u20131073","journal-title":"Pediatrics"},{"key":"5467_CR36","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1136\/archdischild-2014-306873","volume":"100","author":"S Leroux","year":"2015","unstructured":"Leroux S, Zhao W, B\u00e9tr\u00e9mieux P, Pladys P, Saliba E, Jacqz-Aigrain E, on behalf of the French Society of Neonatology (2015) Therapeutic guidelines for prescribing antibiotics in neonates should be evidence-based: a French national survey. Arch Dis Child 100:394\u2013398","journal-title":"Arch Dis Child"},{"key":"5467_CR37","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1055\/s-0033-1361933","volume":"31","author":"EM Hsieh","year":"2014","unstructured":"Hsieh EM, Hornik CP, Clark RH, Laughon MM, Benjamin DK Jr, Smith PB, Best Pharmaceuticals for Children Act-Pediatric Trials N (2014) Medication use in the neonatal intensive care unit. Am J Perinatol 31:811\u2013821","journal-title":"Am J Perinatol"},{"key":"5467_CR38","doi-asserted-by":"publisher","first-page":"e20476","DOI":"10.1371\/journal.pone.0020476","volume":"6","author":"R Boulkedid","year":"2011","unstructured":"Boulkedid R, Abdoul H, Loustau M, Sibony O, Alberti C (2011) Using and reporting the Delphi method for selecting healthcare quality indicators: a systematic review. PLoS ONE 6:e20476","journal-title":"PLoS ONE"},{"key":"5467_CR39","doi-asserted-by":"publisher","first-page":"1491","DOI":"10.1097\/ACM.0000000000001812","volume":"92","author":"S Humphrey-Murto","year":"2017","unstructured":"Humphrey-Murto S, Varpio L, Wood TJ, Gonsalves C, Ufholz LA, Mascioli K, Wang C, Foth T (2017) The Use of the Delphi and Other Consensus Group Methods in Medical Education Research: A Review. Acad Med 92:1491\u20131498","journal-title":"Acad Med"},{"key":"5467_CR40","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/s12874-016-0165-8","volume":"16","author":"BH Eubank","year":"2016","unstructured":"Eubank BH, Mohtadi NG, Lafave MR, Wiley JP, Bois AJ, Boorman RS, Sheps DM (2016) Using the modified Delphi method to establish clinical consensus for the diagnosis and treatment of patients with rotator cuff pathology. BMC Med Res Methodol 16:56","journal-title":"BMC Med Res Methodol"},{"key":"5467_CR41","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.anpedi.2023.02.009","volume":"98","author":"A Perez-Munuzuri","year":"2023","unstructured":"Perez-Munuzuri A, Boix H, Sanchez-Redondo MD, Cernada M, Espinosa-Fernandez MG, Gonzalez-Pacheco N, Martin-Ancel A, Couce ML, Luna MS, en representacion del Comite de Estandares y Junta Directiva y Comite Asesor de la Sociedad Espanola de N (2023) Care levels in neonatal units in Spain: an updated vision for a new reality. An Pediatr (Engl Ed) 98:301\u2013307","journal-title":"An Pediatr (Engl Ed)"},{"key":"5467_CR42","first-page":"46","volume-title":"Standard Organizzativi per l\u2019Assistenza Perinatale","author":"D Baronciani","year":"2021","unstructured":"Baronciani D, Bell\u00f9 R, Franchi M, Gargano G, Jorizzo G, Viora E, Zanini R, Agostiniani R, Bertel\u00e8 P, Bracchi F, Buccella I, Costamagna G, Rin Da, della Mora R, Dasso N, Del Vecchio A, Gennarelli F, Masella C, Portanova A, Simonetto C, Rinaldo D, Romeo N, Vicario M, Zucconi G, (2021) Obiettivi di Sistema, Modello OrganizzativoGenerale e Standard organizzativi per la Rete diAssistenza alla Madre e al Neonato. In: Zanini R (ed) Standard Organizzativi per l\u2019Assistenza Perinatale, 1st edn. IdeaCpa Editore, Roma, pp 46\u2013102","edition":"1"},{"key":"5467_CR43","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jcomdis.2016.07.003","volume":"63","author":"A Wium","year":"2016","unstructured":"Wium A, Gerber B (2016) Ototoxicity management: An investigation into doctors\u2019 knowledge and practices, and the roles of audiologists in a tertiary hospital. S Afr J Commun Disord 63:e1\u2013e15","journal-title":"S Afr J Commun Disord"},{"key":"5467_CR44","doi-asserted-by":"publisher","first-page":"1353","DOI":"10.3390\/ph16101353","volume":"16","author":"S Rivetti","year":"2023","unstructured":"Rivetti S, Romano A, Mastrangelo S, Attina G, Maurizi P, Ruggiero A (2023) Aminoglycosides-Related Ototoxicity: Mechanisms, Risk Factors, and Prevention in Pediatric Patients. Pharmaceuticals (Basel) 16:1353","journal-title":"Pharmaceuticals (Basel)"},{"key":"5467_CR45","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1186\/s12887-015-0479-4","volume":"15","author":"B Vos","year":"2015","unstructured":"Vos B, Senterre C, Lagasse R, SurdiScreen G, Leveque A (2015) Newborn hearing screening programme in Belgium: a consensus recommendation on risk factors. BMC Pediatr 15:160","journal-title":"BMC Pediatr"},{"key":"5467_CR46","doi-asserted-by":"publisher","first-page":"87","DOI":"10.3233\/NPM-181744","volume":"11","author":"F Cianfrone","year":"2018","unstructured":"Cianfrone F, Mammarella F, Ralli M, Evetovic V, Pianura CM, Bellocchi G (2018) Universal newborn hearing screening using A-TEOAE and A-ABR: The experience of a large public hospital. J Neonatal Perinatal Med 11:87\u201392","journal-title":"J Neonatal Perinatal Med"},{"key":"5467_CR47","doi-asserted-by":"publisher","first-page":"1046","DOI":"10.3390\/antibiotics10091046","volume":"10","author":"Garrido F, Allegaert K, Arribas C, Villamor E, Raffaeli G, Paniagua M, Cavallaro G, On Behalf Of European Antibiotics Study Group E","year":"2021","unstructured":"Garrido F, Allegaert K, Arribas C, Villamor E, Raffaeli G, Paniagua M, Cavallaro G, On Behalf Of European Antibiotics Study Group E (2021) Variations in Antibiotic Use and Sepsis Management in Neonatal Intensive Care Units: A European Survey. Antibiotics (Basel) 10:1046","journal-title":"Antibiotics (Basel)"},{"key":"5467_CR48","doi-asserted-by":"publisher","first-page":"e000643","DOI":"10.1136\/bmjpo-2020-000643","volume":"4","author":"B McMullan","year":"2020","unstructured":"McMullan B, Cooper C, Spotswood N, James R, Jones C, Konecny P, Blyth C, Karen T (2020) Antibiotic prescribing in neonatal sepsis: an Australian nationwide survey. BMJ Paediatr Open 4:e000643","journal-title":"BMJ Paediatr Open"},{"key":"5467_CR49","doi-asserted-by":"publisher","first-page":"2647","DOI":"10.1093\/jac\/dkr351","volume":"66","author":"S Kadambari","year":"2011","unstructured":"Kadambari S, Heath PT, Sharland M, Lewis S, Nichols A, Turner MA (2011) Variation in gentamicin and vancomycin dosage and monitoring in UK neonatal units. J Antimicrob Chemother 66:2647\u20132650","journal-title":"J Antimicrob Chemother"},{"key":"5467_CR50","doi-asserted-by":"publisher","first-page":"S29","DOI":"10.1080\/14992027.2018.1460495","volume":"57","author":"D Maru","year":"2018","unstructured":"Maru D, Malky G-A (2018) Current practice of ototoxicity management across the United Kingdom (UK). Int J Audiol 57:S29\u2013S41","journal-title":"Int J Audiol"},{"key":"5467_CR51","doi-asserted-by":"publisher","first-page":"1422","DOI":"10.3390\/antibiotics10111422","volume":"10","author":"S Martin-Mons","year":"2021","unstructured":"Martin-Mons S, Gouyon B, Lorrain S, Abasse S, Alexandre C, Binson G, Brat R, Caeymaex L, Couringa Y, Desbruyeres C, Meglio MD, Escourrou G, Flamein F, Flechelles O, Girard O, Kermorvant-Duchemin E, Lapillonne A, Lafon C, Di Maio M, Gouyon JB (2021) Prescription of Aminoglycosides in 23 French Neonatal Intensive Care Units. Antibiotics (Basel) 10:1422","journal-title":"Antibiotics (Basel)"},{"key":"5467_CR52","unstructured":"Usami S, Nishio S (2018) Nonsyndromic hearing loss and deafness, mitochondrial. In: Adam MP, Feldman J, Mirzaa GM, et al. (eds) GeneReviews\u00ae. Seattle (WA): University of Washington, Seattle, pp 1993-2024. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK1422\/"},{"key":"5467_CR53","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1038\/jp.2012.105","volume":"33","author":"E Zimmerman","year":"2013","unstructured":"Zimmerman E, Lahav A (2013) Ototoxicity in preterm infants: effects of genetics, aminoglycosides, and loud environmental noise. J Perinatol 33:3\u20138","journal-title":"J Perinatol"},{"key":"5467_CR54","first-page":"601","volume":"15","author":"G Cianfrone","year":"2011","unstructured":"Cianfrone G, Pentangelo D, Cianfrone F, Mazzei F, Turchetta R, Orlando MP, Altissimi G (2011) Pharmacological drugs inducing ototoxicity, vestibular symptoms and tinnitus: a reasoned and updated guide. Eur Rev Med Pharmacol Sci 15:601\u2013636","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"5467_CR55","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.heares.2011.05.008","volume":"281","author":"J Xie","year":"2011","unstructured":"Xie J, Talaska AE, Schacht J (2011) New developments in aminoglycoside therapy and ototoxicity. Hear Res 281:28\u201337","journal-title":"Hear Res"},{"key":"5467_CR56","doi-asserted-by":"publisher","first-page":"233","DOI":"10.2165\/11596620-000000000-00000","volume":"14","author":"GM Pacifici","year":"2012","unstructured":"Pacifici GM (2012) Clinical pharmacology of the loop diuretics furosemide and bumetanide in neonates and infants. Paediatr Drugs 14:233\u2013246","journal-title":"Paediatr Drugs"},{"key":"5467_CR57","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1186\/s13052-020-00851-2","volume":"46","author":"VA Manfredini","year":"2020","unstructured":"Manfredini VA, Cerini C, Clavenna A, Dotta A, Caccamo ML, Staffler A, Massenzi L, Rezzonico RM (2020) Furosemide use in Italian neonatal intensive care units: a national survey. Ital J Pediatr 46:86","journal-title":"Ital J Pediatr"},{"key":"5467_CR58","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1136\/archdischild-2013-305309","volume":"101","author":"S Pauwels","year":"2016","unstructured":"Pauwels S, Allegaert K (2016) Therapeutic drug monitoring in neonates. Arch Dis Child 101:377\u2013381","journal-title":"Arch Dis Child"},{"key":"5467_CR59","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1111\/ijpp.12284","volume":"25","author":"N Krzyzaniak","year":"2017","unstructured":"Krzyzaniak N, Bajorek B (2017) A global perspective of the roles of the pharmacist in the NICU. Int J Pharm Pract 25:107\u2013120","journal-title":"Int J Pharm Pract"},{"key":"5467_CR60","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1159\/000293517","volume":"28","author":"TT Lao","year":"1989","unstructured":"Lao TT, Loong EP, Chin RK, Lam YM (1989) Renal function in the newborn. Newborn creatinine related to birth weight, maturity and maternal creatinine. Gynecol Obstet Invest 28:70\u201372","journal-title":"Gynecol Obstet Invest"},{"key":"5467_CR61","doi-asserted-by":"publisher","first-page":"e0196721","DOI":"10.1371\/journal.pone.0196721","volume":"13","author":"H Go","year":"2018","unstructured":"Go H, Momoi N, Kashiwabara N, Haneda K, Chishiki M, Imamura T, Sato M, Goto A, Kawasaki Y, Hosoya M (2018) Neonatal and maternal serum creatinine levels during the early postnatal period in preterm and term infants. PLoS ONE 13:e0196721","journal-title":"PLoS ONE"},{"key":"5467_CR62","doi-asserted-by":"publisher","first-page":"2077","DOI":"10.1007\/s00467-019-04350-3","volume":"35","author":"HJ Murphy","year":"2020","unstructured":"Murphy HJ, Thomas B, Van Wyk B, Tierney SB, Selewski DT, Jetton JG (2020) Nephrotoxic medications and acute kidney injury risk factors in the neonatal intensive care unit: clinical challenges for neonatologists and nephrologists. Pediatr Nephrol 35:2077\u20132088","journal-title":"Pediatr Nephrol"},{"key":"5467_CR63","doi-asserted-by":"publisher","first-page":"553","DOI":"10.3389\/fped.2019.00553","volume":"7","author":"SK Sethi","year":"2019","unstructured":"Sethi SK, Agrawal G, Wazir S, Rohatgi S, Iyengar A, Chakraborty R, Jain R, Nair N, Sinha R, Chakrabarti R, Kumar D, Raina R (2019) Neonatal Acute Kidney Injury: A Survey of Perceptions and Management Strategies Amongst Pediatricians and Neonatologists. Front Pediatr 7:553","journal-title":"Front Pediatr"},{"key":"5467_CR64","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1023\/A:1015615130459","volume":"17","author":"JT Kotaniemi","year":"2001","unstructured":"Kotaniemi JT, Hassi J, Kataja M, Jonsson E, Laitinen LA, Sovijarvi AR, Lundback B (2001) Does non-responder bias have a significant effect on the results in a postal questionnaire study? Eur J Epidemiol 17:809\u2013817","journal-title":"Eur J Epidemiol"}],"container-title":["European Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-024-05467-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00431-024-05467-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-024-05467-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T03:07:03Z","timestamp":1715828823000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00431-024-05467-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,16]]},"references-count":64,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2024,6]]}},"alternative-id":["5467"],"URL":"https:\/\/doi.org\/10.1007\/s00431-024-05467-w","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-3821579\/v1","asserted-by":"object"}]},"ISSN":["1432-1076"],"issn-type":[{"value":"1432-1076","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,16]]},"assertion":[{"value":"29 December 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 January 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 January 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 March 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The study, complying with the Helsinki Declaration, was approved by the University of Navarra Ethics Committee (CEI UNAV) with code 2023.189. Participants\u2019 submission of surveys was deemed as consent to participate, aligning with the Institutional Review Board\u2019s indications.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Institutional review board statement"}}]}}