{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T07:01:03Z","timestamp":1780124463260,"version":"3.54.0"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T00:00:00Z","timestamp":1775433600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T00:00:00Z","timestamp":1775433600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"ZonMW"},{"name":"Dutch Coeliac Society"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>A novel evaluation of the acceptability of screening and mass screening for celiac disease (CD) in young children at the Preventive Youth Health Care Centres (YHCCs) in the Netherlands. Children aged 1\u20134\u00a0years attending the YHCC Kennemerland region were screened for CD-related symptoms. Symptomatic children were offered a point-of-care (POC) test for CD antibodies. Parents of both symptomatic and asymptomatic children received tailored questionnaires assessing opinions on case finding and mass screening and about distress and anxiety. Parents of POC-positive children received follow-up questionnaires during diagnosis. Questionnaires were completed for 1070 asymptomatic children, 1095 symptomatic participants, and 653 symptomatic non-participants. Sixty-one children tested POC-positive; 39 follow-up questionnaires were returned. Reported distress and anxiety were mild, mainly after a positive POC result. Among parents who refused testing, 32% (80\/248) cited practical obstacles. Of those who accepted, 88% would participate again in the future. Overall, 87% considered mass screening a good idea, but only 68% (2125\/3111) would allow participation of their asymptomatic child.<\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusion<\/jats:italic>\n                    : Active case finding and mass screening for CD is well accepted in the Dutch population, with limited distress for parents and children. Reducing practical barriers is essential for successful implementation.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:table-wrap>\n                      <jats:table>\n                        <jats:tbody>\n                          <jats:tr>\n                            <jats:td colspan=\"3\">\n                              <jats:bold>What is Known:<\/jats:bold>\n                              \u2022\n                              <jats:italic>Celiac disease (CD) is difficult to diagnose promptly, and undetected CD is associated with short- and long-term complications<\/jats:italic>\n                              .\u2022\n                              <jats:italic>Strategies for secondary prevention of CD include active case finding and mass screening, but the acceptability of these strategies is not well known<\/jats:italic>\n                              .\n                            <\/jats:td>\n                          <\/jats:tr>\n                          <jats:tr>\n                            <jats:td colspan=\"3\">\n                              <jats:bold>What is New:<\/jats:bold>\n                              \u2022\n                              <jats:italic>Active case finding for CD via a questionnaire and, when indicated, a subsequent POC test in children aged 0\u20134\u00a0years, is generally well accepted by parents and health care providers<\/jats:italic>\n                              .\u2022\n                              <jats:italic>Parents who refused participation mentioned the absence of significant symptoms and practical barriers as the main reasons<\/jats:italic>\n                              .\n                            <\/jats:td>\n                          <\/jats:tr>\n                        <\/jats:tbody>\n                      <\/jats:table>\n                    <\/jats:table-wrap>\n                  <\/jats:p>","DOI":"10.1007\/s00431-026-06809-6","type":"journal-article","created":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T05:15:17Z","timestamp":1775452517000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Acceptability of screening for celiac disease at Youth Health Care Centers in The Netherlands"],"prefix":"10.1007","volume":"185","author":[{"given":"Willemien","family":"de Vries","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"van Geloven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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Ethical approval was obtained from the Medical Ethics Committee of Leiden-Den Haag-Delft (METC-LDD; P17.240).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent for participation in the study was obtained by all participants, in conformity with Dutch legislation.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The funder had no role in the design or conduct of this study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Role of funder"}}],"article-number":"237"}}