{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T08:43:40Z","timestamp":1776933820781,"version":"3.51.2"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T00:00:00Z","timestamp":1773532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T00:00:00Z","timestamp":1773532800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"DOI":"10.1007\/s00431-026-06860-3","type":"journal-article","created":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T05:32:36Z","timestamp":1773552756000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Relationship of chemerin with nutritional status and appetitive traits in early childhood: a cross-sectional study"],"prefix":"10.1007","volume":"185","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8422-6637","authenticated-orcid":false,"given":"Aylin","family":"Y\u00fcksel \u00dclker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6592-9652","authenticated-orcid":false,"given":"\u0130lker Tolga","family":"\u00d6zgen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8972-6494","authenticated-orcid":false,"given":"Ya\u015far","family":"Cesur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,15]]},"reference":[{"issue":"5","key":"6860_CR1","doi-asserted-by":"publisher","DOI":"10.3390\/children8050388","volume":"8","author":"K Sdravou","year":"2021","unstructured":"Sdravou K, Fotoulaki M, Emmanouilidou-Fotoulaki E, Andreoulakis E, Makris G, Sotiriadou F, Printza A (2021) Feeding problems in typically developing young children, a population-based study. Children 8(5):388. https:\/\/doi.org\/10.3390\/children8050388","journal-title":"Children"},{"issue":"1","key":"6860_CR2","doi-asserted-by":"publisher","first-page":"11","DOI":"10.4274\/jpr.58077","volume":"2","author":"N Kaymaz","year":"2015","unstructured":"Kaymaz N, Bulur N, Yildirim S, Cevizci S, Topaloglu N, Tekin M, Binnetoglu FA, Ozmert E (2015) Appetite related undernutrition in school children: is it a false perception of parents. J Pediatr Res 2(1):11\u201316","journal-title":"J Pediatr Res"},{"key":"6860_CR3","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2025.1484827","volume":"12","author":"X Sun","year":"2025","unstructured":"Sun X, Liu B, Yuan Y, Rong Y, Pang R, Li Q (2025) Neural and hormonal mechanisms of appetite regulation during eating. Front Nutr 12:1484827. https:\/\/doi.org\/10.3389\/fnut.2025.1484827","journal-title":"Front Nutr"},{"issue":"7","key":"6860_CR4","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1515\/hsz-2021-0409","volume":"403","author":"TF Fischer","year":"2022","unstructured":"Fischer TF, Beck-Sickinger AG (2022) Chemerin\u2013exploring a versatile adipokine. Biol Chem 403(7):625\u2013642. https:\/\/doi.org\/10.1515\/hsz-2021-0409","journal-title":"Biol Chem"},{"issue":"1","key":"6860_CR5","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1124\/pr.116.013177","volume":"70","author":"AJ Kennedy","year":"2018","unstructured":"Kennedy AJ, Davenport AP (2018) International union of basic and clinical pharmacology CIII: chemerin receptors CMKLR1 (Chemerin1) and GPR1 (Chemerin2) nomenclature, pharmacology, and function. Pharmacol Rev 70(1):174\u2013196. https:\/\/doi.org\/10.1124\/pr.116.013177","journal-title":"Pharmacol Rev"},{"key":"6860_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygcen.2021.113721","volume":"304","author":"A Estienne","year":"2021","unstructured":"Estienne A, Ram\u00e9 C, Ganier P, Chahnamian M, Barbe A, Grandhaye J, Dubois JP, Batailler M, Migaud M, Lecompte F, Adriaensen H (2021) Chemerin impairs food intake and body weight in chicken: focus on hypothalamic neuropeptides gene expression and AMPK signaling pathway. Gen Comp Endocrinol 304:113721. https:\/\/doi.org\/10.1016\/j.ygcen.2021.113721","journal-title":"Gen Comp Endocrinol"},{"key":"6860_CR7","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2021.119897","volume":"284","author":"DM Samy","year":"2021","unstructured":"Samy DM, Mostafa DK, Abdelmonsif DA, Ismail CA, Hassaan PS (2021) Crosstalk of hypothalamic chemerin, histamine, and AMPK in diet- and olanzapine-induced obesity in rats. Life Sci 284:119897. https:\/\/doi.org\/10.1016\/j.lfs.2021.119897","journal-title":"Life Sci"},{"issue":"6","key":"6860_CR8","doi-asserted-by":"publisher","DOI":"10.1002\/edm2.70012","volume":"7","author":"AR Akbarzadeh","year":"2024","unstructured":"Akbarzadeh AR, Borzouei S, Khazaei S, Jazaeri M (2024) Evaluation of the relationship between salivary adipokine levels with appetite and anthropometric indices in patients with type 2 diabetes. Endocrinol Diabetes Metab 7(6):e70012. https:\/\/doi.org\/10.1002\/edm2.70012","journal-title":"Endocrinol Diabetes Metab"},{"issue":"10","key":"6860_CR9","doi-asserted-by":"publisher","first-page":"1760","DOI":"10.21037\/tp-24-264","volume":"13","author":"J Zhang","year":"2024","unstructured":"Zhang J, Gu C, Deng M, Yang L, Yang W (2024) Circulating chemerin and interleukin-6 in children with obesity: possible metabolic risk predictors. Transl Pediatr 13(10):1760. https:\/\/doi.org\/10.21037\/tp-24-264","journal-title":"Transl Pediatr"},{"key":"6860_CR10","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1143755","volume":"14","author":"M Krajewska","year":"2023","unstructured":"Krajewska M, Witkowska-S\u0119dek E, Rumi\u0144ska M, Kucharska AM, Stelmaszczyk-Emmel A, Sobol M, Majcher A, Pyr\u017cak B (2023) The link between vitamin D, chemerin and metabolic profile in overweight and obese children - preliminary results. Front Endocrinol (Lausanne) 14:1143755. https:\/\/doi.org\/10.3389\/fendo.2023.1143755","journal-title":"Front Endocrinol (Lausanne)"},{"key":"6860_CR11","doi-asserted-by":"publisher","DOI":"10.1177\/1179556519853780","volume":"13","author":"HJ Ba","year":"2019","unstructured":"Ba HJ, Xu LL, Qin YZ, Chen HS (2019) Serum chemerin levels correlate with determinants of metabolic syndrome in obese children and adolescents. Clin Med Insights Pediatr 13:1179556519853780. https:\/\/doi.org\/10.1177\/1179556519853780","journal-title":"Clin Med Insights Pediatr"},{"issue":"7","key":"6860_CR12","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1111\/1469-7610.00792","volume":"42","author":"J Wardle","year":"2001","unstructured":"Wardle J, Guthrie CA, Sanderson S, Rapoport L (2001) Development of the children\u2019s eating behaviour questionnaire. J Child Psychol Psychiatry 42(7):963\u2013970. https:\/\/doi.org\/10.1111\/1469-7610.00792","journal-title":"J Child Psychol Psychiatry"},{"issue":"4","key":"6860_CR13","first-page":"287","volume":"12","author":"R Y\u0131lmaz","year":"2011","unstructured":"Y\u0131lmaz R, Esmeray H, Erkorkmaz \u00dc (2011) Adaptation study of the Turkish children\u2019s eating behavior questionnaire. Anatol J Psychiatry 12(4):287\u2013294","journal-title":"Anatol J Psychiatry"},{"issue":"4","key":"6860_CR14","doi-asserted-by":"publisher","first-page":"280","DOI":"10.4274\/jcrpe.2183","volume":"7","author":"O Neyzi","year":"2015","unstructured":"Neyzi O, Bundak R, G\u00f6k\u00e7ay G, G\u00fcn\u00f6z H, Furman A, Darendeliler F, Ba\u015f F (2015) Reference values for weight, height, head circumference, and body mass index in Turkish children. J Clin Res Pediatr Endocrinol 7(4):280. https:\/\/doi.org\/10.4274\/jcrpe.2183","journal-title":"J Clin Res Pediatr Endocrinol"},{"key":"6860_CR15","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2023.1247630","volume":"10","author":"MM Ko","year":"2023","unstructured":"Ko MM, Lee SH, Chang GT, Lee B (2023) Reliability and validity of a Korean version of the children\u2019s eating behavior questionnaire in anorexia context. Front Nutr 10:1247630. https:\/\/doi.org\/10.3389\/fnut.2023.1247630","journal-title":"Front Nutr"},{"issue":"3","key":"6860_CR16","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10030591","volume":"10","author":"K Zdanowicz","year":"2022","unstructured":"Zdanowicz K, Bobrus-Chociej A, Lebensztejn DM (2022) Chemerin as potential biomarker in pediatric diseases: a PRISMA-compliant study. Biomedicines 10(3):591. https:\/\/doi.org\/10.3390\/biomedicines10030591","journal-title":"Biomedicines"},{"issue":"10","key":"6860_CR17","doi-asserted-by":"publisher","first-page":"1743","DOI":"10.1038\/s41366-018-0157-3","volume":"42","author":"P Niklowitz","year":"2018","unstructured":"Niklowitz P, Rothermel J, Lass N, Barth A, Reinehr T (2018) Link between chemerin, central obesity, and parameters of the metabolic syndrome: findings from a longitudinal study in obese children participating in a lifestyle intervention. Int J Obes 42(10):1743\u20131752. https:\/\/doi.org\/10.1038\/s41366-018-0157-3","journal-title":"Int J Obes"},{"issue":"5","key":"6860_CR18","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1080\/13813455.2021.1912103","volume":"129","author":"I Jialal","year":"2023","unstructured":"Jialal I (2023) Chemerin levels in metabolic syndrome: a promising biomarker. Arch Physiol Biochem 129(5):1009\u20131011. https:\/\/doi.org\/10.1080\/13813455.2021.1912103","journal-title":"Arch Physiol Biochem"},{"key":"6860_CR19","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.1076951","volume":"13","author":"Y Gao","year":"2023","unstructured":"Gao Y, Xin C, Fan H, Sun X, Wang H (2023) Circulating apelin and chemerin levels in patients with polycystic ovary syndrome: a meta-analysis. Front Endocrinol 13:1076951. https:\/\/doi.org\/10.3389\/fendo.2022.1076951","journal-title":"Front Endocrinol"},{"key":"6860_CR20","unstructured":"O\u015bwi\u0119cimska J, Ziora K, Suwa\u0142a A, \u015awi\u0119tochowska E, Gorczyca P, Ziora-Jakutowicz K, Machura E, Szczepa\u0144ska M, Ostrowska Z, Ziora D, Szalecki M (2014) Chemerin serum levels in girls with anorexia nervosa. Neuroendocrinol Lett 35(6):490\u2013496"},{"issue":"1","key":"6860_CR21","doi-asserted-by":"publisher","first-page":"26","DOI":"10.5603\/EP.a2021.0103","volume":"73","author":"Z Ostrowska","year":"2022","unstructured":"Ostrowska Z, Morawiecka-Pietrzak M, Pluskiewicz W, \u015awi\u0119tochowska E, Strzelczyk J, Go\u0142\u0105bek K, Ga\u017adzicka J, Ziora K (2022) The relationship between chemerin, bone metabolism, the RANKL\/RANK\/OPG system, and bone mineral density in girls with anorexia nervosa. Endokrynol Pol 73(1):26\u201334. https:\/\/doi.org\/10.5603\/EP.a2021.0103","journal-title":"Endokrynol Pol"},{"issue":"1","key":"6860_CR22","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines12010033","volume":"12","author":"A Schmid","year":"2023","unstructured":"Schmid A, Roderfeld M, Karrasch T, Roeb E, Sch\u00e4ffler A (2023) Serum chemerin is decreased by Roux-en-Y gastric bypass and low calorie-formula diet in obese individuals. Biomedicines 12(1):33. https:\/\/doi.org\/10.3390\/biomedicines12010033","journal-title":"Biomedicines"},{"issue":"04","key":"6860_CR23","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1055\/a-1129-6785","volume":"52","author":"M Askarpour","year":"2020","unstructured":"Askarpour M, Alizadeh S, Hadi A, Symonds ME, Miraghajani M, Sheikhi A, Ghaedi E (2020) Effect of bariatric surgery on the circulating level of adiponectin, chemerin, plasminogen activator inhibitor- 1, leptin, resistin, and visfatin: a systematic review and meta-analysis. Horm Metab Res 52(04):207\u2013215. https:\/\/doi.org\/10.1055\/a-1129-6785","journal-title":"Horm Metab Res"},{"key":"6860_CR24","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2021.111369","volume":"535","author":"P Fang","year":"2021","unstructured":"Fang P, Han L, Yu M, Han S, Wang M, Huang Y, Guo W, Wei Q, Shang W, Min W (2021) Development of metabolic dysfunction in mice lacking chemerin. Mol Cell Endocrinol 535:111369. https:\/\/doi.org\/10.1016\/j.mce.2021.111369","journal-title":"Mol Cell Endocrinol"},{"key":"6860_CR25","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.regpep.2012.12.001","volume":"181","author":"E Stelmanska","year":"2013","unstructured":"Stelmanska E, Sledzinski T, Turyn J, Presler M, Korczynska J, Swierczynski J (2013) Chemerin gene expression is regulated by food restriction and food restriction\u2013refeeding in rat adipose tissue but not in liver. Regul Pept 181:22\u201329. https:\/\/doi.org\/10.1016\/j.regpep.2012.12.001","journal-title":"Regul Pept"},{"issue":"4","key":"6860_CR26","doi-asserted-by":"publisher","first-page":"445","DOI":"10.18388\/abp.2019_2858","volume":"66","author":"K Sznurkowska","year":"2019","unstructured":"Sznurkowska K, Ka\u017amierska K, \u015aledzi\u0144ski T, Zagierski M, Liberek A, Szlagatys-Sidorkiewicz A (2019) Serum chemerin level, cytokine profile and nutritional status in children with cystic fibrosis. Acta Biochim Pol 66(4):445\u20139. https:\/\/doi.org\/10.18388\/abp.2019_2858","journal-title":"Acta Biochim Pol"},{"issue":"4","key":"6860_CR27","doi-asserted-by":"publisher","first-page":"E556","DOI":"10.1210\/jc.2011-2937","volume":"97","author":"K Landgraf","year":"2012","unstructured":"Landgraf K, Friebe D, Ullrich T, Kratzsch J, Dittrich K, Herberth G, Adams V, Kiess W, Erbs S, K\u00f6rner A (2012) Chemerin as a mediator between obesity and vascular inflammation in children. J Clin Endocrinol Metab 97(4):E556\u2013E564. https:\/\/doi.org\/10.1210\/jc.2011-2937","journal-title":"J Clin Endocrinol Metab"},{"issue":"20","key":"6860_CR28","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17207575","volume":"17","author":"G Rowicka","year":"2020","unstructured":"Rowicka G, Dyl\u0105g H, Che\u0142chowska M, Weker H, Ambroszkiewicz J (2020) Serum calprotectin and chemerin concentrations as markers of low-grade inflammation in prepubertal children with obesity. Int J Environ Res Public Health 17(20):7575. https:\/\/doi.org\/10.3390\/ijerph17207575","journal-title":"Int J Environ Res Public Health"},{"issue":"12","key":"6860_CR29","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0113915","volume":"9","author":"Y Li","year":"2014","unstructured":"Li Y, Shi B, Li S (2014) Association between serum chemerin concentrations and clinical indices in obesity or metabolic syndrome: a meta-analysis. PLoS One 9(12):e113915. https:\/\/doi.org\/10.1371\/journal.pone.0113915","journal-title":"PLoS One"},{"issue":"6","key":"6860_CR30","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8060775","volume":"8","author":"U Keller","year":"2019","unstructured":"Keller U (2019) Nutritional laboratory markers in malnutrition. J Clin Med 8(6):775. https:\/\/doi.org\/10.3390\/jcm8060775","journal-title":"J Clin Med"},{"issue":"8","key":"6860_CR31","first-page":"1575","volume":"65","author":"FK Beck","year":"2002","unstructured":"Beck FK, Rosenthal TC (2002) Prealbumin: a marker for nutritional evaluation. Am Fam Physician 65(8):1575\u20131578","journal-title":"Am Fam Physician"},{"issue":"7","key":"6860_CR32","doi-asserted-by":"publisher","first-page":"1656","DOI":"10.1161\/ATVBAHA.118.311219","volume":"38","author":"S Zylla","year":"2018","unstructured":"Zylla S, D\u00f6rr M, V\u00f6lzke H, Schminke U, Felix SB, Nauck M, Friedrich N (2018) Association of circulating chemerin with subclinical parameters of atherosclerosis: results of a population-based study. Arterioscler Thromb Vasc Biol 38(7):1656\u20131664. https:\/\/doi.org\/10.1161\/ATVBAHA.118.311219","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"1","key":"6860_CR33","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-016-0353-x","volume":"15","author":"VE Varga","year":"2016","unstructured":"Varga VE, L\u0151rincz H, Zs\u00edros N, F\u00fcl\u00f6p P, Seres I, Paragh G, Balla J, Harangi M (2016) Impact of selective LDL apheresis on serum chemerin levels in patients with hypercholesterolemia. Lipids Health Dis 15(1):182. https:\/\/doi.org\/10.1186\/s12944-016-0353-x","journal-title":"Lipids Health Dis"},{"issue":"4","key":"6860_CR34","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines12040924","volume":"12","author":"L Zhao","year":"2024","unstructured":"Zhao L, Zhou J, Abbasi F, Fathzadeh M, Knowles JW, Leung LL, Morser J (2024) Chemerin in participants with or without insulin resistance and diabetes. Biomedicines 12(4):924. https:\/\/doi.org\/10.3390\/biomedicines12040924","journal-title":"Biomedicines"},{"key":"6860_CR35","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2021.111504","volume":"541","author":"A L\u00e9niz","year":"2022","unstructured":"L\u00e9niz A, Gonz\u00e1lez M, Besn\u00e9 I, Carr-Ugarte H, G\u00f3mez-Garc\u00eda I, Portillo MP (2022) Role of chemerin in the control of glucose homeostasis. Mol Cell Endocrinol 541:111504. https:\/\/doi.org\/10.1016\/j.mce.2021.111504","journal-title":"Mol Cell Endocrinol"},{"key":"6860_CR36","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/786708","volume":"1","author":"J He","year":"2015","unstructured":"He J, Li JC, Xie H, Xu ZH, Sun YW, Shan Q (2015) Serum chemerin levels in relation to osteoporosis and bone mineral density: a case-control study. Dis Markers 1:786708. https:\/\/doi.org\/10.1155\/2015\/786708","journal-title":"Dis Markers"},{"key":"6860_CR37","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2021.101322","volume":"53","author":"L Han","year":"2021","unstructured":"Han L, Zhang Y, Wan S, Wei Q, Shang W, Huang G, Fang P, Min W (2021) Loss of chemerin triggers bone remodeling in vivo and in vitro. Mol Metab 53:101322. https:\/\/doi.org\/10.1016\/j.molmet.2021.101322","journal-title":"Mol Metab"},{"issue":"2","key":"6860_CR38","doi-asserted-by":"publisher","first-page":"384","DOI":"10.12669\/pjms.37.2.3907","volume":"37","author":"S Tariq","year":"2021","unstructured":"Tariq S, Tariq S, Shahzad M (2021) Association of serum chemerin with calcium, alkaline phosphatase and bone mineral density in postmenopausal females. Pak J Med Sci 37(2):384\u2013388. https:\/\/doi.org\/10.12669\/pjms.37.2.3907","journal-title":"Pak J Med Sci"}],"container-title":["European Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-026-06860-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00431-026-06860-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-026-06860-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T07:54:47Z","timestamp":1776930887000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00431-026-06860-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,15]]},"references-count":38,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,4]]}},"alternative-id":["6860"],"URL":"https:\/\/doi.org\/10.1007\/s00431-026-06860-3","relation":{},"ISSN":["1432-1076"],"issn-type":[{"value":"1432-1076","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,15]]},"assertion":[{"value":"26 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 March 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 March 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 March 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was conducted in accordance with the principles of the Declaration of Helsinki and was approved by the Bezmialem Vakif University Ethics Committee (approval no. 71306642\u2013050.01.04).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Written informed consent was obtained from the parents.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"183"}}