{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T07:01:08Z","timestamp":1780124468677,"version":"3.54.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr"],"DOI":"10.1007\/s00431-026-07001-6","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T03:21:35Z","timestamp":1777346495000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Systemic hypertension in very preterm infants: a population-based study"],"prefix":"10.1007","volume":"185","author":[{"given":"Aseel","family":"Sa\u2019deh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth Ellen","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Vincer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip D.","family":"Acott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej","family":"Kajetanowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walid","family":"El-Naggar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,28]]},"reference":[{"issue":"5","key":"7001_CR1","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1007\/s00467-018-3977-4","volume":"34","author":"M Starr","year":"2019","unstructured":"Starr M, Flynn J (2019) Neonatal hypertension: cases, causes, and clinical approach. Pediatr Nephrol 34(5):787\u2013799","journal-title":"Pediatr Nephrol"},{"issue":"3","key":"7001_CR2","doi-asserted-by":"publisher","first-page":"186","DOI":"10.2174\/1573402112666161129155224","volume":"12","author":"A Pillai","year":"2016","unstructured":"Pillai A, Sharma D, Kadam P (2016) Hypertension in the neonatal period: an update. Curr Hypertens Rev 12(3):186\u2013195","journal-title":"Curr Hypertens Rev"},{"issue":"5","key":"7001_CR3","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2020.101138","volume":"25","author":"J Flynn","year":"2020","unstructured":"Flynn J (2020) The hypertensive neonate. Semin Fetal Neonatal Med 25(5):101138","journal-title":"Semin Fetal Neonatal Med"},{"key":"7001_CR4","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1007\/s004670050771","volume":"14","author":"J Flynn","year":"2000","unstructured":"Flynn J (2000) Neonatal hypertension: diagnosis and management. Pediatr Nephrol 14:332\u2013341","journal-title":"Pediatr Nephrol"},{"issue":"1","key":"7001_CR5","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1136\/archdischild-2020-318871","volume":"107","author":"Y Singh","year":"2022","unstructured":"Singh Y, McGeoch L, Job S (2022) Fifteen-minute consultation: neonatal hypertension. Arch Dis Child Educ Pract Ed 107(1):2\u20138","journal-title":"Arch Dis Child Educ Pract Ed"},{"key":"7001_CR6","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1007\/s00467-018-3996-1","volume":"34","author":"M Harer","year":"2019","unstructured":"Harer M, Kent A (2019) Neonatal hypertension: an educational review. Pediatr Nephrol 34:1009\u20131018","journal-title":"Pediatr Nephrol"},{"issue":"6","key":"7001_CR7","first-page":"e357","volume":"18","author":"K Mistry","year":"2017","unstructured":"Mistry K, Gupta C (2017) Neonatal hypertension. Neo reviews 18(6):e357\u2013e37","journal-title":"Neo reviews"},{"key":"7001_CR8","unstructured":"Zubrow AB, Hulman S, Kushner H, Falkner B (1995) Determinants of BP in infants admitted to neonatal intensive care units: a prospective multicenter study. Philadelphia Blood Pressure Study Group. J Perinatol 15(6):470\u20139"},{"key":"7001_CR9","doi-asserted-by":"publisher","first-page":"2081","DOI":"10.1007\/s00467-007-0603-2","volume":"22","author":"WA Seliem","year":"2007","unstructured":"Seliem WA, Falk MC, Shadbolt B et al (2007) Antenatal and postnatal risk factors for neonatal hypertension and infant follow-up. Pediatr Nephrol 22:2081\u2013208","journal-title":"Pediatr Nephrol"},{"key":"7001_CR10","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1093\/ajh\/5.2.51","volume":"5","author":"HP Singh","year":"1992","unstructured":"Singh HP, Hurley RM, Myers TF (1992) Neonatal hypertension: incidence and risk factors. Am J Hypertens 5:51\u201355","journal-title":"Am J Hypertens"},{"key":"7001_CR11","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1111\/j.1479-828X.2009.01018.x","volume":"49","author":"AL Kent","year":"2009","unstructured":"Kent AL, Shadbolt B, Hu E et al (2009) Do maternal- or pregnancy-associated disease states affect blood pressure in the early neonatal period? Aust N Z J Obstet Gynaecol 49:364\u201370","journal-title":"Aust N Z J Obstet Gynaecol"},{"issue":"6","key":"7001_CR12","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1016\/j.jash.2011.08.001","volume":"5","author":"D Blowey","year":"2011","unstructured":"Blowey D, Duda P, Stokes P et al (2011) Incidence and treatment of hypertension in the neonatal intensive care unit. J Am Soc Hypertens 5(6):478\u201383","journal-title":"J Am Soc Hypertens"},{"issue":"1","key":"7001_CR13","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/s00467-010-1755-z","volume":"27","author":"JM Dionne","year":"2012","unstructured":"Dionne JM, Abitbol CL, Flynn JT (2012) Hypertension in infancy: diagnosis, management and outcome. Pediatr Nephrol 27(1):17\u201332","journal-title":"Pediatr Nephrol"},{"issue":"28","key":"7001_CR14","first-page":"1","volume":"18","author":"M Bertagnolli","year":"2016","unstructured":"Bertagnolli M, Luu TM, Lewadnowski AJ et al (2016) Preterm birth and hypertension: is there a link? Curr Hypertens Rep 18(28):1\u20138","journal-title":"Curr Hypertens Rep"},{"key":"7001_CR15","volume-title":"Fetal and infant origins of adult disease","author":"DJ Barker","year":"1992","unstructured":"Barker DJ (1992) Fetal and infant origins of adult disease. wiley-Blackwell, Hoboken New Jersey"},{"key":"7001_CR16","volume-title":"Mothers, babies and diseases later in life","author":"D Barker","year":"1998","unstructured":"Barker D (1998) Mothers, babies and diseases later in life. BMJ publishing group, London United Kingdom"},{"issue":"10","key":"7001_CR17","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1177\/0009922811409918","volume":"50","author":"T Vasylyeva","year":"2011","unstructured":"Vasylyeva T, Chennasamudram S, Okogbo M (2011) Can we predict hypertension among preterm children? Clin Pediatr 50(10):936\u2013942","journal-title":"Clin Pediatr"},{"key":"7001_CR18","volume-title":"Scientific information retrieval: user\u2019s manual","author":"BS Robinson","year":"1980","unstructured":"Robinson BS, Anderson GD, Cohen E (1980) Scientific information retrieval: user\u2019s manual, Second edition. SIR Inc, Evanston, IL","edition":"Second edition"},{"issue":"4","key":"7001_CR19","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1542\/peds.82.4.527","volume":"82","author":"AT Shennan","year":"1988","unstructured":"Shennan AT, Dunn MS, Ohlsson A et al (1988) Abnormal pulmonary outcomes in premature infants: prediction from oxygen requirement in the neonatal period. Pediatrics 82(4):527\u2013532","journal-title":"Pediatrics"},{"issue":"7","key":"7001_CR20","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1001\/archopht.123.7.991","volume":"123","author":"International Committee for the Classification of Retinopathy of Prematurity","year":"2005","unstructured":"International Committee for the Classification of Retinopathy of Prematurity (2005) The international classification of retinopathy of prematurity revisited. Arch Ophthalmol 123(7):991\u2013999","journal-title":"Arch Ophthalmol"},{"issue":"4","key":"7001_CR21","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1016\/S0022-3476(78)80282-0","volume":"92","author":"LA Papile","year":"1978","unstructured":"Papile LA, Burstein J, Burstein R et al (1978) Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. J Pediatr 92(4):529\u2013534","journal-title":"J Pediatr"},{"key":"7001_CR22","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197801000-00001","author":"MJ Bell","year":"1978","unstructured":"Bell MJ, Ternberg JL, Feigin RD et al (1978) Neonatal necrotizing enterocolitis. Ann Surg. https:\/\/doi.org\/10.1097\/00000658-197801000-00001","journal-title":"Ann Surg"},{"key":"7001_CR23","doi-asserted-by":"crossref","unstructured":"Bayley N (2006) Manual for Bayley scale of infant and toddler development. San Antonio, Texas: Pearson Cinical. https:\/\/www.pearsonclinical.com\/childhood\/products\/100000123\/bayleyscales-of-infant-and-toddler-development-third-editionbayle","DOI":"10.1037\/t14978-000"},{"issue":"1","key":"7001_CR24","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1016\/S0022-3476(05)81587-2","volume":"123","author":"AH Hoon Jr","year":"1993","unstructured":"Hoon AH Jr, Pulsifer MB, Gopalan R et al (1993) Clinical adaptive test\/clinical linguistic auditory milestone scale in early cognitive assessment. J Pediatr 123(1):S1-8","journal-title":"J Pediatr"},{"key":"7001_CR25","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1016\/j.jpeds.2011.09.047","volume":"160","author":"T Moore","year":"2012","unstructured":"Moore T, Johnson S, Haider S et al (2012) Relationship between test scores using the second and third version of the Bayley scales in extremely preterm infants. J Pediatr 160:553\u2013558","journal-title":"J Pediatr"},{"key":"7001_CR26","doi-asserted-by":"publisher","first-page":"943","DOI":"10.1038\/s41372-022-01577-1","volume":"43","author":"G Altit","year":"2023","unstructured":"Altit G, Cayouette F, Dorval V et al (2023) Systemic hypertension in preterm infants and neurodevelopmental outcomes. J Perinatol 43:943\u2013945","journal-title":"J Perinatol"},{"key":"7001_CR27","volume":"3","author":"D Roberts","year":"2017","unstructured":"Roberts D, Brown J, Medley N et al (2017) Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev 3:CD004454","journal-title":"Cochrane Database Syst Rev"},{"key":"7001_CR28","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1016\/S0022-3476(84)80501-6","volume":"104","author":"SH Abman","year":"1984","unstructured":"Abman SH, Warady BA, Lum G et al (1984) Systemic hypertension in infants with bronchopulmonary dysplasia. J Pediatr 104:928\u2013931","journal-title":"J Pediatr"},{"key":"7001_CR29","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1055\/s-2007-994716","volume":"10","author":"AH Anderson","year":"1993","unstructured":"Anderson AH, Warady BA, Daily DK et al (1993) Systemic hypertension in infants with severe bronchopulmonary dysplasia: associated clinical factors. Am J Perinatol 10:190\u2013193","journal-title":"Am J Perinatol"},{"key":"7001_CR30","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1055\/s-2007-993889","volume":"15","author":"A Alagappan","year":"1998","unstructured":"Alagappan A, Malloy MH (1998) Systemic hypertension in very low-birth weight infants with bronchopulmonary dysplasia: incidence and risk factors. Am J Perinatol 15:3\u20138","journal-title":"Am J Perinatol"},{"key":"7001_CR31","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1046\/j.1440-1754.1999.355392.x","volume":"35","author":"NY Boo","year":"1999","unstructured":"Boo NY, Wong NC, Zulkifli SS et al (1999) Risk factors associated with umbilical vascular catheter-associated thrombosis in newborn infants. J Paediatr Child Health 35:460\u2013465","journal-title":"J Paediatr Child Health"},{"issue":"8","key":"7001_CR32","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1038\/sj.jp.7211558","volume":"26","author":"ER-J Teng","year":"2006","unstructured":"Teng ER-J, Wu T-J, Sharma R, Garrison RD, Hudak ML (2006) Neonatal hypotension in premature infants born to preeclamptic mothers. J Perinatol 26(8):471\u20135","journal-title":"J Perinatol"},{"key":"7001_CR33","doi-asserted-by":"crossref","unstructured":"Schell-Feith EA, Kist-van Holthe JE, Conneman N, van Zwieten PH, Holscher HC, Zonderland HM, Brand R, van der Heijden BJ (2000) Etiology of nephrocalcinosis in preterm neonates: association of nutritional intake and urinary parameters. Kidney Int 58(5):2102\u201310","DOI":"10.1111\/j.1523-1755.2000.00383.x"},{"issue":"3","key":"7001_CR34","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1542\/peds.2006-2639","volume":"119","author":"JE Kist-van Holthe","year":"2007","unstructured":"Kist-van Holthe JE, van Zwieten PH, Schell-Feith EA et al (2007) Is nephrocalcinosis in preterm neonates harmful for long-term blood pressure and renal function? Pediatrics 119(3):468\u201375","journal-title":"Pediatrics"},{"issue":"11","key":"7001_CR35","doi-asserted-by":"publisher","first-page":"1102","DOI":"10.1007\/s00467-003-1235-9","volume":"18","author":"EA Schell-Feith","year":"2003","unstructured":"Schell-Feith EA, Kist-van Holthe JE, van Zwieten PH et al (2003) Preterm neonates with nephrocalcinosis: natural course and renal function. Pediatr Nephrol 18(11):1102\u20138","journal-title":"Pediatr Nephrol"}],"container-title":["European Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-026-07001-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00431-026-07001-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00431-026-07001-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T06:02:12Z","timestamp":1780120932000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00431-026-07001-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,28]]},"references-count":35,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,5]]}},"alternative-id":["7001"],"URL":"https:\/\/doi.org\/10.1007\/s00431-026-07001-6","relation":{},"ISSN":["1432-1076"],"issn-type":[{"value":"1432-1076","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,28]]},"assertion":[{"value":"9 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 April 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 April 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 April 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was performed in line with the principles of the Declaration of Helsinki. The study was approved by the local Research Ethics Board of the IWK Health Centre (Project # 1023165).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate and consent to publish"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"310"}}