{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:03:22Z","timestamp":1740107002228,"version":"3.37.3"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T00:00:00Z","timestamp":1598572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T00:00:00Z","timestamp":1598572800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81873917"],"award-info":[{"award-number":["81873917"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cancer Res Clin Oncol"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1007\/s00432-020-03350-3","type":"journal-article","created":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T13:03:14Z","timestamp":1598619794000},"page":"3385-3388","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Elevated carcinoembryonic antigen in patients with COVID-19 pneumonia"],"prefix":"10.1007","volume":"146","author":[{"given":"Chongtu","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianwen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiacheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Songjiang","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7795-7041","authenticated-orcid":false,"given":"Bin","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,8,28]]},"reference":[{"issue":"8","key":"3350_CR1","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1111\/j.1440-1843.2012.02231.x","volume":"17","author":"A Fahim","year":"2012","unstructured":"Fahim A, Crooks MG, Wilmot R, Campbell AP, Morice AH, Hart SP (2012) Serum carcinoembryonic antigen correlates with severity of idiopathic pulmonary fibrosis. Respirology 17(8):1247\u20131252","journal-title":"Respirology"},{"issue":"3","key":"3350_CR2","doi-asserted-by":"publisher","first-page":"407","DOI":"10.7326\/0003-4819-94-3-407","volume":"94","author":"DM Goldenberg","year":"1981","unstructured":"Goldenberg DM, Neville AM, Carter AC, Go VLW, Hol-Yoke ED, Isselbacher KJ, Schwartz M (1981) Carcinoembryonic antigen: its role as a marker in the management of cancer. A National Institutes of Health Consensus Development Conference. Ann Internal Med 94(3):407\u2013409","journal-title":"Ann Internal Med"},{"key":"3350_CR3","doi-asserted-by":"publisher","first-page":"1708","DOI":"10.1056\/NEJMoa2002032","volume":"18","author":"WJ Guan","year":"2020","unstructured":"Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, Liu L, Shan H, Lei CL, Hui DSC et al (2020) Clinical characteristics of Coronavirus disease 2019 in China. N Engl J Med 18:1708\u20131720","journal-title":"N Engl J Med"},{"key":"3350_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.02.052","author":"M Hoffmann","year":"2020","unstructured":"Hoffmann M, Kleine-Weber H, Schroeder S, Kruger N, Herrler T, Erichsen S, Schiergens TS, Herrler G, Wu NH, Nitsche A et al (2020) SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell. https:\/\/doi.org\/10.1016\/j.cell.2020.02.052","journal-title":"Cell"},{"key":"3350_CR5","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1136\/gutjnl-2020-320926","volume":"6","author":"X Jin","year":"2020","unstructured":"Jin X, Lian JS, Hu JH, Gao J, Zheng L, Zhang YM, Hao SR, Jia HY, Cai H, Zhang XL et al (2020) Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms. Gut 6:1002\u20131009","journal-title":"Gut"},{"key":"3350_CR6","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1136\/gutjnl-2020-321013","volume":"69","author":"L Lin","year":"2020","unstructured":"Lin L, Jiang X, Zhang Z, Huang S, Zhang Z, Fang Z, Gu Z, Gao L, Shi H, Mai L et al (2020) Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection. Gut 69:997\u20131001","journal-title":"Gut"},{"issue":"11","key":"3350_CR7","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1136\/gut.14.11.880","volume":"14","author":"AH Rule","year":"1973","unstructured":"Rule AH, Goleski-Reilly C, Sachar DB, Vandevoorde J, Janowitz HD (1973) Circulating carcinoembryonic antigen (CEA): relationship to clinical status of patients with inflammatory bowel disease. Gut 14(11):880\u2013884","journal-title":"Gut"},{"key":"3350_CR8","doi-asserted-by":"publisher","first-page":"1831","DOI":"10.1053\/j.gastro.2020.02.055","volume":"6","author":"F Xiao","year":"2020","unstructured":"Xiao F, Tang M, Zheng X, Liu Y, Li X, Shan H (2020) Evidence for gastrointestinal infection of SARS-CoV-2. Gastroenterology 6:1831\u20131833","journal-title":"Gastroenterology"}],"container-title":["Journal of Cancer Research and Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00432-020-03350-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00432-020-03350-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00432-020-03350-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T23:53:06Z","timestamp":1630108386000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00432-020-03350-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,28]]},"references-count":8,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["3350"],"URL":"https:\/\/doi.org\/10.1007\/s00432-020-03350-3","relation":{},"ISSN":["0171-5216","1432-1335"],"issn-type":[{"type":"print","value":"0171-5216"},{"type":"electronic","value":"1432-1335"}],"subject":[],"published":{"date-parts":[[2020,8,28]]},"assertion":[{"value":"20 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 August 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All authors declare no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study protocol was complied with the principles of the Declaration of Helsinki and was approved by the institutional review board of the Union Hospital, Tongji Medical college, Huazhong University of Science and Technology and Wuhan Jinyintan Hospital.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The institutional ethics committee of Wuhan Union Hospital and Wuhan Jinyintan Hospital agree to waive the consent to participate.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}