{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T16:05:14Z","timestamp":1784563514037,"version":"3.55.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2020,11,4]],"date-time":"2020-11-04T00:00:00Z","timestamp":1604448000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,11,4]],"date-time":"2020-11-04T00:00:00Z","timestamp":1604448000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cancer Res Clin Oncol"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>We performed breast-conserving surgery (BCS) using periareolar incisions for cancers located far from the nipple\u2013areolar complex (NAC) and examined if BCS via a periareolar incision maximized cosmesis and maintained oncologic safety. One of the most important goals of BCS is to improve cosmesis after surgery and quality of life, but the skin incision can affect cosmesis based on the tumor location.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Fifty-five patients with breast cancers located far from the NAC underwent BCS via periareolar incisions between January 2017 and April 2018. If a sentinel lymph node biopsy was required, another skin incision was created in the axilla using the conventional technique. Medical records of patients were reviewed retrospectively.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The mean patient age was 48.1\u2009\u00b1\u200910.6\u00a0years. The mean tumor size was 1.8\u2009\u00b1\u20091.0\u00a0cm (range 0.2\u20134.5\u00a0cm) on preoperative magnetic resonance imaging (MRI); the mean distance from the NAC to the tumor was 5.9\u2009\u00b1\u20091.9\u00a0cm (range 4.0\u201312.3\u00a0cm). Patients with cancers in the subareolar area were excluded even though the distance from the nipple was\u2009&gt;\u20094\u00a0cm on MRI. Negative microscopic margins were obtained in all patients. There was no surgical complication such as seroma, bleeding, or infection. Re-operation was not needed. All patients received whole breast radiation therapy. After surgery and radiation therapy, periareolar incision scars were nearly invisible.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>For cancers located far from the NAC, BCS via periareolar incisions is feasible and leads to superior cosmesis in selective patients. Moreover, BCS seems oncologically safe, although long-term outcomes need to be evaluated.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00432-020-03385-6","type":"journal-article","created":{"date-parts":[[2020,11,4]],"date-time":"2020-11-04T12:45:54Z","timestamp":1604493954000},"page":"893-900","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Feasibility and safety of breast-conserving surgery via a periareolar incision for cancers located far from the nipple\u2013areolar complex: a retrospective study"],"prefix":"10.1007","volume":"147","author":[{"given":"Joohyun","family":"Woo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihae","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Se Hyun","family":"Paek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2863-9346","authenticated-orcid":false,"given":"Woosung","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,11,4]]},"reference":[{"issue":"1","key":"3385_CR1","doi-asserted-by":"publisher","first-page":"e0191056","DOI":"10.1371\/journal.pone.0191056","volume":"13","author":"S Bromberg","year":"2018","unstructured":"Bromberg S, Moraes P, Ades F (2018) Prime incision: a minimally invasive approach to breast cancer surgical treatment\u2014a 2 cohort retrospective comparison with conventional breast conserving surgery. 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