{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T18:56:20Z","timestamp":1770749780900,"version":"3.50.0"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2022,10,15]],"date-time":"2022-10-15T00:00:00Z","timestamp":1665792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,10,15]],"date-time":"2022-10-15T00:00:00Z","timestamp":1665792000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cancer Res Clin Oncol"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1007\/s00432-022-04405-3","type":"journal-article","created":{"date-parts":[[2022,10,15]],"date-time":"2022-10-15T09:02:48Z","timestamp":1665824568000},"page":"4805-4816","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Characteristics, treatment, and outcome of diverticulitis after immune checkpoint inhibitor treatment in patients with malignancies"],"prefix":"10.1007","volume":"149","author":[{"given":"Austin R.","family":"Thomas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mostafa","family":"Eyada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miho","family":"Kono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishnavathana","family":"Varatharajalu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guofan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kavea","family":"Panneerselvam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malek","family":"Shatila","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Altan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John A.","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao Chi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Ali","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gottumukkala S.","family":"Raju","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anusha S.","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinghong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,10,15]]},"reference":[{"issue":"30","key":"4405_CR1","doi-asserted-by":"crossref","first-page":"2738","DOI":"10.1200\/JCO.19.00320","volume":"37","author":"H Abu-Sbeih","year":"2019","unstructured":"Abu-Sbeih H, Ali F, Naqash A, Owen D, Patel S, Otterson G et al (2019a) Resumption of immune checkpoint inhibitor therapy after immune-mediated colitis. J Clin Oncol 37(30):2738\u20132745","journal-title":"J Clin Oncol"},{"issue":"4","key":"4405_CR2","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1007\/s00262-019-02303-1","volume":"68","author":"H Abu-Sbeih","year":"2019","unstructured":"Abu-Sbeih H, Ali F, Qiao W, Lu Y, Patel S, Diab A et al (2019b) Immune checkpoint inhibitor-induced colitis as a predictor of survival in metastatic melanoma. Cancer Immunol Immunother 68(4):553\u2013561","journal-title":"Cancer Immunol Immunother"},{"issue":"10 Online","key":"4405_CR3","doi-asserted-by":"crossref","first-page":"e278","DOI":"10.1111\/j.1463-1318.2009.02122.x","volume":"12","author":"S Alonso","year":"2010","unstructured":"Alonso S, Pera M, Par\u00e9s D, Pascual M, Gil M, Courtier R et al (2010) Outpatient treatment of patients with uncomplicated acute diverticulitis. Colorectal Dis 12(10 Online):e278-282","journal-title":"Colorectal Dis"},{"issue":"6","key":"4405_CR4","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/j.amjsurg.2003.08.019","volume":"186","author":"A Bahadursingh","year":"2003","unstructured":"Bahadursingh A, Virgo K, Kaminski D, Longo W (2003) Spectrum of disease and outcome of complicated diverticular disease. Am J Surg 186(6):696\u2013701","journal-title":"Am J Surg"},{"issue":"2","key":"4405_CR5","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s00261-015-0560-3","volume":"41","author":"A Barina","year":"2016","unstructured":"Barina A, Bashir M, Howard B, Hanks B, Salama A, Jaffe T (2016) Isolated recto-sigmoid colitis: a new imaging pattern of ipilimumab-associated colitis. Abdom Radiol (NY) 41(2):207\u2013214","journal-title":"Abdom Radiol (NY)"},{"key":"4405_CR6","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1186\/s12916-015-0455-8","volume":"13","author":"A Bertrand","year":"2015","unstructured":"Bertrand A, Kostine M, Barnetche T, Truchetet M, Schaeverbeke T (2015) Immune related adverse events associated with anti-CTLA-4 antibodies: systematic review and meta-analysis. BMC Med 13:211","journal-title":"BMC Med"},{"issue":"9","key":"4405_CR7","doi-asserted-by":"crossref","first-page":"4334","DOI":"10.1128\/IAI.00553-07","volume":"75","author":"E Beswick","year":"2007","unstructured":"Beswick E, Pinchuk I, Das S, Powell D, Reyes V (2007) Expression of the programmed death ligand 1, B7\u2013H1, on gastric epithelial cells after Helicobacter pylori exposure promotes development of CD4+ CD25+ FoxP3+ regulatory T cells. Infect Immun 75(9):4334\u20134341","journal-title":"Infect Immun"},{"key":"4405_CR8","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.3389\/fimmu.2018.01125","volume":"9","author":"E Beswick","year":"2018","unstructured":"Beswick E, Grim C, Singh A, Aguirre J, Tafoya M, Qiu S et al (2018) Expression of programmed death-ligand 1 by human colonic CD90+ stromal cells differs between ulcerative colitis and crohn\u2019s disease and determines their capacity to suppress Th1 cells. Front Immunol 9:1125","journal-title":"Front Immunol"},{"issue":"2","key":"4405_CR9","first-page":"84","volume":"31","author":"SK B\u00f6hm","year":"2015","unstructured":"B\u00f6hm SK (2015) Risk factors for diverticulosis, diverticulitis, diverticular perforation, and bleeding: a plea for more subtle history taking. Viszeralmedizin 31(2):84\u201394","journal-title":"Viszeralmedizin"},{"issue":"4","key":"4405_CR10","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1002\/bjs.8688","volume":"99","author":"A Chabok","year":"2012","unstructured":"Chabok A, P\u00e5hlman L, Hjern F, Haapaniemi S, Smedh K (2012) Randomized clinical trial of antibiotics in acute uncomplicated diverticulitis. Br J Surg 99(4):532\u2013539","journal-title":"Br J Surg"},{"issue":"2","key":"4405_CR11","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1093\/ibd\/izy240","volume":"25","author":"K Choi","year":"2019","unstructured":"Choi K, Abu-Sbeih H, Samdani R, Gonzalez G, Raju G, Richards D et al (2019) Can immune checkpoint inhibitors induce microscopic colitis or a brand new entity? Inflamm Bowel Dis 25(2):385\u2013393","journal-title":"Inflamm Bowel Dis"},{"issue":"1","key":"4405_CR12","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1002\/bjs.10309","volume":"104","author":"L Daniels","year":"2017","unstructured":"Daniels L, \u00dcnl\u00fc \u00c7, de Korte N, van Dieren S, Stockmann H, Vrounraets B et al (2017) Randomized clinical trial of observational versus antibiotic treatment for a first episode of CT-proven uncomplicated acute diverticulitis. Br J Surg 104(1):52\u201361","journal-title":"Br J Surg"},{"issue":"6","key":"4405_CR13","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1007\/DCR.0b013e3181cdb243","volume":"53","author":"D Etzioni","year":"2010","unstructured":"Etzioni D, Chiu V, Cannom R, Burchette R, Haigh P, Abbas M (2010) Outpatient treatment of acute diverticulitis: rates and predictors of failure. Dis Colon Rectum 53(6):861\u2013865","journal-title":"Dis Colon Rectum"},{"issue":"3","key":"4405_CR14","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1046\/j.1463-1318.2002.00349.x","volume":"4","author":"J Evans","year":"2002","unstructured":"Evans J, Cooper J, Roediger W (2002) Diverticular colitis - therapeutic and aetiological considerations. Colorectal Dis 4(3):208\u2013212","journal-title":"Colorectal Dis"},{"issue":"9","key":"4405_CR15","doi-asserted-by":"crossref","first-page":"2726","DOI":"10.1007\/s00464-019-06882-z","volume":"33","author":"N Francis","year":"2019","unstructured":"Francis N, Sylla P, Abou-Khalil M, Arolfo S, Berler D, Curtis N (2019) EAES and SAGES 2018 consensus conference on acute diverticulitis management: evidence-based recommendations for clinical practice. Surg Endosc 33(9):2726\u20132741","journal-title":"Surg Endosc"},{"issue":"3","key":"4405_CR16","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/DCR.0b013e3182028576","volume":"54","author":"J Hall","year":"2011","unstructured":"Hall J, Roberts P, Ricciardi R, Read T, Scheirey C, Wald C et al (2011) Long-term follow-up after an initial episode of diverticulitis: what are the predictors of recurrence? Dis Colon Rectum 54(3):283\u2013288","journal-title":"Dis Colon Rectum"},{"issue":"28","key":"4405_CR17","doi-asserted-by":"crossref","first-page":"3193","DOI":"10.1200\/JCO.2015.60.8448","volume":"33","author":"T Horvat","year":"2015","unstructured":"Horvat T, Adel N, Thu-Oanh D, Momtaz P, Postow M, Callahan M et al (2015) Immune-related adverse events, need for systemic immunosuppression, and effects on survival and time to treatment failure in patients with melanoma treated with ipilimumab at memorial sloan kettering cancer center. J Clin Oncol 33(28):3193\u20133198","journal-title":"J Clin Oncol"},{"key":"4405_CR18","doi-asserted-by":"crossref","first-page":"5437135","DOI":"10.1155\/2018\/5437135","volume":"2018","author":"A Iannone","year":"2018","unstructured":"Iannone A, Ruospo M, Wong G, Barone M, Principi M, Di Leo A et al (2018) Mesalazine for people with diverticular disease: a systematic review of randomized controlled trials. Can J Gastroenterol Hepatol 2018:5437135","journal-title":"Can J Gastroenterol Hepatol"},{"issue":"7536","key":"4405_CR19","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1136\/bmj.332.7536.271","volume":"332","author":"S Janes","year":"2006","unstructured":"Janes S, Meagher A, Frizelle F (2006) Management of diverticulitis. BMJ 332(7536):271\u2013275","journal-title":"BMJ"},{"issue":"5","key":"4405_CR20","doi-asserted-by":"crossref","first-page":"W468","DOI":"10.2214\/AJR.12.9751","volume":"200","author":"K Kim","year":"2013","unstructured":"Kim K, Ramaiya N, Krajewski K, Shinagare A, Howard S, Jagannathan J et al (2013) Ipilimumab-associated colitis: CT findings. AJR Am J Roentgenol 200(5):W468\u2013W474","journal-title":"AJR Am J Roentgenol"},{"issue":"1","key":"4405_CR21","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1007\/s00384-004-0615-3","volume":"20","author":"I Koutroubakis","year":"2005","unstructured":"Koutroubakis I, Antoniou P, Tzardi M, Kouroumalis E (2005) The spectrum of segmental colitis associated with diverticulosis. Int J Colorectal Dis 20(1):28\u201332","journal-title":"Int J Colorectal Dis"},{"issue":"4","key":"4405_CR22","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1055\/s-0037-1607467","volume":"31","author":"R Kucejko","year":"2018","unstructured":"Kucejko R, Poggio J (2018) Considerations and changes in the evaluation, management, and outcomes in the management of diverticular disease: the diagnosis, pathology, and treatment of diverticular colitis. Clin Colon Rectal Surg 31(4):221\u2013225","journal-title":"Clin Colon Rectal Surg"},{"issue":"12","key":"4405_CR23","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1038\/ajg.2017.398","volume":"112","author":"P Liu","year":"2017","unstructured":"Liu P, Cao Y, Keeley B, Tam I, Wu K, Strate L et al (2017) Adherence to a healthy lifestyle is associated with a lower risk of diverticulitis among men. Am J Gastroenterol 112(12):1868\u20131876","journal-title":"Am J Gastroenterol"},{"issue":"9","key":"4405_CR24","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/S1470-2045(17)30428-X","volume":"18","author":"G Long","year":"2017","unstructured":"Long G, Atkinson V, Cebon J, Jameson M, Fitzharris B, McNeil C et al (2017) Standard-dose pembrolizumab in combination with reduced-dose ipilimumab for patients with advanced melanoma (KEYNOTE-029): an open-label, phase 1b trial. Lancet Oncol 18(9):1202\u20131210","journal-title":"Lancet Oncol"},{"issue":"1","key":"4405_CR25","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1053\/j.gastro.2018.03.057","volume":"155","author":"W Ma","year":"2018","unstructured":"Ma W, Jovani M, Liu P, Nguyen L, Cao Y, Tam I et al (2018) Association between obesity and weight change and risk of diverticulitis in women. Gastroenterology 155(1):58\u201366","journal-title":"Gastroenterology"},{"issue":"3","key":"4405_CR26","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1159\/000236903","volume":"27","author":"J M\u00e4kel\u00e4","year":"2010","unstructured":"M\u00e4kel\u00e4 J, Kiviniemi H, Laitinen S (2010) Spectrum of disease and outcome among patients with acute diverticulitis. Dig Surg 27(3):190\u2013196","journal-title":"Dig Surg"},{"issue":"5","key":"4405_CR27","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1111\/pcmr.12383","volume":"28","author":"D Minor","year":"2015","unstructured":"Minor D, Puzanov I, Callahan M, Hug B, Hoos A (2015) Severe gastrointestinal toxicity with administration of trametinib in combination with dabrafenib and ipilimumab. Pigment Cell Melanoma Res 28(5):611\u2013612","journal-title":"Pigment Cell Melanoma Res"},{"issue":"3","key":"4405_CR28","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1001\/jama.2013.282025","volume":"311","author":"A Morris","year":"2014","unstructured":"Morris A, Regenbogen S, Hardiman K, Hendren S (2014) Sigmoid diverticulitis: a systematic review. JAMA 311(3):287\u2013297","journal-title":"JAMA"},{"issue":"4","key":"4405_CR29","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s10151-012-0847-0","volume":"16","author":"P Moya","year":"2012","unstructured":"Moya P, Arryo A, P\u00e9rez-Legaz J, Serrano P, Candela F, Soriano-Irigaray L et al (2012) Applicability, safety and efficiency of outpatient treatment in uncomplicated diverticulitis. Tech Coloproctol 16(4):301\u2013307","journal-title":"Tech Coloproctol"},{"issue":"8","key":"4405_CR30","doi-asserted-by":"crossref","first-page":"896","DOI":"10.6004\/jnccn.2020.7675","volume":"19","author":"K Panneerselvam","year":"2021","unstructured":"Panneerselvam K, Amin R, Wei D, Tan D, Lum P, Zhang H et al (2021) Clinicopathologic features, treatment response, and outcomes of immune checkpoint inhibitor-related esophagitis. J Natl Compr Canc Netw 19(8):896\u2013904","journal-title":"J Natl Compr Canc Netw"},{"issue":"9","key":"4405_CR31","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1038\/s41423-019-0256-7","volume":"16","author":"C Ponce de Le\u00f3n","year":"2019","unstructured":"Ponce de Le\u00f3n C, L\u00f3pez-Casado M, Lorite P, Palomeque T, Torres M (2019) Dysregulation of the PD-1\/PD-L1 pathway contributes to the pathogenesis of celiac disease. Cell Mol Immunol 16(9):777\u2013779","journal-title":"Cell Mol Immunol"},{"issue":"4","key":"4405_CR32","doi-asserted-by":"crossref","first-page":"2102","DOI":"10.4049\/jimmunol.0802769","volume":"182","author":"E Reynoso","year":"2009","unstructured":"Reynoso E, Elpek K, Francisco L, Bronson R, Bellemare-Pelletier A, Sharpe A et al (2009) Intestinal tolerance is converted to autoimmune enteritis upon PD-1 ligand blockade. J Immunol 182(4):2102\u20132112","journal-title":"J Immunol"},{"issue":"26","key":"4405_CR33","doi-asserted-by":"crossref","first-page":"2521","DOI":"10.1056\/NEJMoa1503093","volume":"372","author":"C Robert","year":"2015","unstructured":"Robert C, Schachter J, Long G, Arance A, Grob J, Mortier L et al (2015) Pembrolizumab versus ipilimumab in advanced melanoma. N Engl J Med 372(26):2521\u20132532","journal-title":"N Engl J Med"},{"issue":"8","key":"4405_CR34","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1002\/bjs.11191","volume":"106","author":"S Rottier","year":"2019","unstructured":"Rottier S, Dijk S, Geloven A, Schreurs W, Draaisma W, Enst W et al (2019) Meta-analysis of the role of colonoscopy after an episode of left-sided acute diverticulitis. Br J Surg 106(8):988\u2013997","journal-title":"Br J Surg"},{"issue":"3","key":"4405_CR35","doi-asserted-by":"crossref","first-page":"203","DOI":"10.9738\/CC64.1","volume":"97","author":"J Rueda","year":"2012","unstructured":"Rueda J, Jimenez A, Caro A, Feliu F, Escuder J, Gris F et al (2012) Home treatment of uncomplicated acute diverticulitis. Int Surg 97(3):203\u2013209","journal-title":"Int Surg"},{"issue":"7","key":"4405_CR36","first-page":"1229","volume":"72","author":"H Salzman","year":"2005","unstructured":"Salzman H, Lillie D (2005) Diverticular disease: diagnosis and treatment. Am Fam Physician 72(7):1229\u20131234","journal-title":"Am Fam Physician"},{"issue":"5","key":"4405_CR37","first-page":"1764","volume":"12","author":"T Shan","year":"2019","unstructured":"Shan T, Chen S, Wu T, Yang Y, Li S, Chen X (2019) PD-L1 expression in colon cancer and its relationship with clinical prognosis. Int J Clin Exp Pathol 12(5):1764\u20131769","journal-title":"Int J Clin Exp Pathol"},{"issue":"2","key":"4405_CR38","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1097\/SLA.0000000000000294","volume":"259","author":"P Sharma","year":"2014","unstructured":"Sharma P, Eglinton T, Hider P, Frizelle F (2014) Systematic review and meta-analysis of the role of routine colonic evaluation after radiologically confirmed acute diverticulitis. Ann Surg 259(2):263\u2013272","journal-title":"Ann Surg"},{"issue":"7","key":"4405_CR39","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.1053\/j.gastro.2015.10.001","volume":"149","author":"L Strate","year":"2015","unstructured":"Strate L, Peery A, Neumann I (2015) American gastroenterological association institute technical review on the management of acute diverticulitis. Gastroenterology 149(7):1950\u20131976","journal-title":"Gastroenterology"},{"issue":"5","key":"4405_CR40","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1080\/00365521.2019.1594356","volume":"54","author":"T Tang","year":"2019","unstructured":"Tang T, Abu-Sbeih H, Luo W, Lum P, Qiao W et al (2019) Upper gastrointestinal symptoms and associated endoscopic and histological features in patients receiving immune checkpoint inhibitors. Scand J Gastroenterol 54(5):538\u2013545","journal-title":"Scand J Gastroenterol"},{"issue":"7","key":"4405_CR41","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1097\/MEG.0000000000001713","volume":"32","author":"A Tursi","year":"2020","unstructured":"Tursi A (2020) Immune checkpoint inhibitors-induced acute diverticulitis. Eur J Gastroenterol Hepatol 32(7):893\u2013895","journal-title":"Eur J Gastroenterol Hepatol"},{"issue":"5","key":"4405_CR42","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1111\/j.1463-1318.2009.01969.x","volume":"12","author":"A Tursi","year":"2010","unstructured":"Tursi A, Elsei W, Brandimarte G, Giorgetti G, Lecca P, Cesare L et al (2010) The endoscopic spectrum of segmental colitis associated with diverticulosis. Colorectal Dis 12(5):464\u2013470","journal-title":"Colorectal Dis"},{"key":"4405_CR43","doi-asserted-by":"crossref","first-page":"730","DOI":"10.3389\/fphar.2017.00730","volume":"8","author":"P Wang","year":"2017","unstructured":"Wang P, Chen Y, Song S, Wang T, Ji W, Li S et al (2017) Immune-related adverse events associated with anti-PD-1\/PD-L1 treatment for malignancies: a meta-analysis. Front Pharmacol 8:730","journal-title":"Front Pharmacol"},{"issue":"8","key":"4405_CR44","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1093\/ibd\/izy104","volume":"24","author":"Y Wang","year":"2018","unstructured":"Wang Y, Abu-Sbeih H, Mao E, Ali N, Qiao W, Trinh V et al (2018a) Endoscopic and histologic features of immune checkpoint inhibitor-related colitis. Inflamm Bowel Dis 24(8):1695\u20131705","journal-title":"Inflamm Bowel Dis"},{"issue":"1","key":"4405_CR45","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s40425-018-0346-6","volume":"6","author":"Y Wang","year":"2018","unstructured":"Wang Y, Abu-Sbeih H, Mao E, Ali N, Ali F, Qiao W et al (2018b) Immune-checkpoint inhibitor-induced diarrhea and colitis in patients with advanced malignancies: retrospective review at MD Anderson. J Immunother Cancer 6(1):37","journal-title":"J Immunother Cancer"},{"issue":"12","key":"4405_CR46","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1038\/s41591-018-0238-9","volume":"24","author":"Y Wang","year":"2018","unstructured":"Wang Y, Wiesnoski D, Helmink B, Gopalakrishnan V, Choi K, DuPont H et al (2018c) Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis. Nat Med 24(12):1804\u20131808","journal-title":"Nat Med"},{"key":"4405_CR47","doi-asserted-by":"crossref","first-page":"830","DOI":"10.2119\/molmed.2016.00150","volume":"22","author":"Y Wu","year":"2017","unstructured":"Wu Y, Chung C, Chen Y, Monaghan S, Patel S, Huang X et al (2017) A novel role for programmed cell death receptor ligand-1 (PD-L1) in sepsis-induced intestinal dysfunction. Mol Med 22:830\u2013840","journal-title":"Mol Med"},{"issue":"6","key":"4405_CR48","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1002\/emp2.12209","volume":"1","author":"S Yeung","year":"2020","unstructured":"Yeung S, Qdaisat A, Chaftari P, Lipe D, Merlin J, Rajha E et al (2020) Diagnosis and management of immune-related adverse effects of immune checkpoint therapy in the emergency department. J Am Coll Emerg Physicians Open 1(6):1637\u20131659","journal-title":"J Am Coll Emerg Physicians Open"},{"issue":"6382","key":"4405_CR49","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1126\/science.aar6918","volume":"359","author":"L Zitvogel","year":"2018","unstructured":"Zitvogel L, Ma Y, Raoult D, Kroemer G, Gajewski T (2018) The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies. Science 359(6382):1366\u20131370","journal-title":"Science"}],"container-title":["Journal of Cancer Research and Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00432-022-04405-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00432-022-04405-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00432-022-04405-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,15]],"date-time":"2023-07-15T14:12:12Z","timestamp":1689430332000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00432-022-04405-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,15]]},"references-count":49,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["4405"],"URL":"https:\/\/doi.org\/10.1007\/s00432-022-04405-3","relation":{},"ISSN":["0171-5216","1432-1335"],"issn-type":[{"value":"0171-5216","type":"print"},{"value":"1432-1335","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,15]]},"assertion":[{"value":"3 September 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 October 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 October 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The ethics approval for this study was granted by the institutional review board at The University of Texas MD Anderson Cancer Center (PA18-0472). Patient consent was waived for this study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"This study was granted a waiver of patient consent.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}