{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T12:39:33Z","timestamp":1769171973946,"version":"3.49.0"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,11,20]],"date-time":"2022-11-20T00:00:00Z","timestamp":1668902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,11,20]],"date-time":"2022-11-20T00:00:00Z","timestamp":1668902400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"the Shanghai Sailing Program","award":["No. 22YF1435900"],"award-info":[{"award-number":["No. 22YF1435900"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cancer Res Clin Oncol"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1007\/s00432-022-04482-4","type":"journal-article","created":{"date-parts":[[2022,11,20]],"date-time":"2022-11-20T17:02:21Z","timestamp":1668963741000},"page":"231-245","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Identification of molecular subtypes based on chromatin regulator and tumor microenvironment infiltration characterization in papillary renal cell carcinoma"],"prefix":"10.1007","volume":"149","author":[{"given":"Qilin","family":"Tang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deshen","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaoliang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,11,20]]},"reference":[{"key":"4482_CR1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23158141","author":"RK Alseksek","year":"2022","unstructured":"Alseksek RK, Ramadan WS, Saleh E, El-Awady R (2022) The role of HDACs in the response of cancer cells to cellular stress and the potential for therapeutic intervention. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms23158141","journal-title":"Int J Mol Sci"},{"issue":"7","key":"4482_CR2","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1016\/j.trecan.2020.02.003","volume":"6","author":"J Cao","year":"2020","unstructured":"Cao J, Yan Q (2020) Cancer Epigenetics, tumor immunity, and immunotherapy. Trends Cancer 6(7):580\u2013592. https:\/\/doi.org\/10.1016\/j.trecan.2020.02.003","journal-title":"Trends Cancer"},{"issue":"11","key":"4482_CR3","doi-asserted-by":"publisher","first-page":"661.e667","DOI":"10.1016\/j.urolonc.2017.06.060","volume":"35","author":"T Chandrasekar","year":"2017","unstructured":"Chandrasekar T, Klaassen Z, Goldberg H, Kulkarni GS, Hamilton RJ, Fleshner NE (2017) Metastatic renal cell carcinoma: patterns and predictors of metastases-A contemporary population-based series. Urol Oncol 35(11):661.e667-661.e614. https:\/\/doi.org\/10.1016\/j.urolonc.2017.06.060","journal-title":"Urol Oncol"},{"key":"4482_CR4","doi-asserted-by":"publisher","first-page":"2815187","DOI":"10.1155\/2022\/2815187","volume":"2022","author":"J Chen","year":"2022","unstructured":"Chen J, Cao L, Ma J, Yue C, Zhu D, An R, Wang X, Guo Y, Gu B (2022) HDAC8 promotes liver metastasis of colorectal cancer via inhibition of IRF1 and upregulation of SUCNR1. Oxid Med Cell Longev 2022:2815187. https:\/\/doi.org\/10.1155\/2022\/2815187","journal-title":"Oxid Med Cell Longev"},{"key":"4482_CR5","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22115578","author":"CR Clapier","year":"2021","unstructured":"Clapier CR (2021) Sophisticated conversations between chromatin and chromatin remodelers, and dissonances in cancer. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms22115578","journal-title":"Int J Mol Sci"},{"issue":"1","key":"4482_CR6","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1016\/j.critrevonc.2015.05.008","volume":"96","author":"G Courthod","year":"2015","unstructured":"Courthod G, Tucci M, Di Maio M, Scagliotti GV (2015) Papillary renal cell carcinoma: a review of the current therapeutic landscape. Crit Rev Oncol Hematol 96(1):100\u2013112. https:\/\/doi.org\/10.1016\/j.critrevonc.2015.05.008","journal-title":"Crit Rev Oncol Hematol"},{"issue":"10","key":"4482_CR7","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/j.urolonc.2018.10.027","volume":"38","author":"C D'Avella","year":"2020","unstructured":"D\u2019Avella C, Abbosh P, Pal SK, Geynisman DM (2020) Mutations in renal cell carcinoma. Urol Oncol 38(10):763\u2013773. https:\/\/doi.org\/10.1016\/j.urolonc.2018.10.027","journal-title":"Urol Oncol"},{"issue":"10","key":"4482_CR8","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1038\/s41585-018-0052-7","volume":"15","author":"AA de Cubas","year":"2018","unstructured":"de Cubas AA, Rathmell WK (2018) Epigenetic modifiers: activities in renal cell carcinoma. Nat Rev Urol 15(10):599\u2013614. https:\/\/doi.org\/10.1038\/s41585-018-0052-7","journal-title":"Nat Rev Urol"},{"key":"4482_CR9","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.ejca.2020.02.019","volume":"136","author":"M de Vries-Brilland","year":"2020","unstructured":"de Vries-Brilland M, Gross-Goupil M, Seegers V, Boughalem E, Beuselinck B, Thibault C, Chevreau C, Ladoire S, Barth\u00e9l\u00e9my P, Negrier S, Borchiellini D, Huillard O, Geoffrois L, Gravis G, Saldana C, Thiery-Vuillemin A, Escudier B, Ravaud A, Albiges L (2020) Are immune checkpoint inhibitors a valid option for papillary renal cell carcinoma? A multicentre retrospective study. Eur J Cancer 136:76\u201383. https:\/\/doi.org\/10.1016\/j.ejca.2020.02.019","journal-title":"Eur J Cancer"},{"issue":"6","key":"4482_CR10","first-page":"537","volume":"10","author":"B Delahunt","year":"1997","unstructured":"Delahunt B, Eble JN (1997) Papillary renal cell carcinoma: a clinicopathologic and immunohistochemical study of 105 tumors. Mod Pathol 10(6):537\u2013544","journal-title":"Mod Pathol"},{"key":"4482_CR11","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1186\/s12014-016-9132-y","volume":"13","author":"JF Fahrmann","year":"2016","unstructured":"Fahrmann JF, Grapov D, Phinney BS, Stroble C, DeFelice BC, Rom W, Gandara DR, Zhang Y, Fiehn O, Pass H, Miyamoto S (2016) Proteomic profiling of lung adenocarcinoma indicates heightened DNA repair, antioxidant mechanisms and identifies LASP1 as a potential negative predictor of survival. Clin Proteomics 13:31. https:\/\/doi.org\/10.1186\/s12014-016-9132-y","journal-title":"Clin Proteomics"},{"issue":"9","key":"4482_CR12","doi-asserted-by":"publisher","first-page":"e107468","DOI":"10.1371\/journal.pone.0107468","volume":"9","author":"P Geeleher","year":"2014","unstructured":"Geeleher P, Cox N, Huang RS (2014) pRRophetic: an R package for prediction of clinical chemotherapeutic response from tumor gene expression levels. PLoS ONE 9(9):e107468. https:\/\/doi.org\/10.1371\/journal.pone.0107468","journal-title":"PLoS ONE"},{"key":"4482_CR13","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1038\/s41525-018-0054-7","volume":"3","author":"KB Givechian","year":"2018","unstructured":"Givechian KB, Wnuk K, Garner C, Benz S, Garban H, Rabizadeh S, Niazi K, Soon-Shiong P (2018) Identification of an immune gene expression signature associated with favorable clinical features in Treg-enriched patient tumor samples. NPJ Genom Med 3:14. https:\/\/doi.org\/10.1038\/s41525-018-0054-7","journal-title":"NPJ Genom Med"},{"key":"4482_CR14","doi-asserted-by":"publisher","first-page":"314620","DOI":"10.1155\/2015\/314620","volume":"2015","author":"L Gu\u00e9ry","year":"2015","unstructured":"Gu\u00e9ry L, Hugues S (2015) Th17 Cell Plasticity and functions in cancer immunity. Biomed Res Int 2015:314620. https:\/\/doi.org\/10.1155\/2015\/314620","journal-title":"Biomed Res Int"},{"key":"4482_CR15","doi-asserted-by":"publisher","first-page":"690796","DOI":"10.3389\/fcell.2021.690796","volume":"9","author":"Y Guo","year":"2021","unstructured":"Guo Y, Liu B, Liu Y, Sun W, Gao W, Mao S, Chen L (2021) Oncogenic chromatin modifier KAT2A activates MCT1 to drive the glycolytic process and tumor progression in renal cell carcinoma. Front Cell Dev Biol 9:690796. https:\/\/doi.org\/10.3389\/fcell.2021.690796","journal-title":"Front Cell Dev Biol"},{"issue":"18","key":"4482_CR16","doi-asserted-by":"publisher","first-page":"4557","DOI":"10.1158\/0008-5472.CAN-18-3962","volume":"79","author":"DC Hinshaw","year":"2019","unstructured":"Hinshaw DC, Shevde LA (2019) The tumor microenvironment innately modulates cancer progression. Cancer Res 79(18):4557\u20134566. https:\/\/doi.org\/10.1158\/0008-5472.CAN-18-3962","journal-title":"Cancer Res"},{"issue":"7","key":"4482_CR17","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1038\/s41571-018-0004-4","volume":"15","author":"A Koch","year":"2018","unstructured":"Koch A, Joosten SC, Feng Z, de Ruijter TC, Draht MX, Melotte V, Smits KM, Veeck J, Herman JG, Van Neste L, Van Criekinge W, De Meyer T, van Engeland M (2018) Analysis of DNA methylation in cancer: location revisited. Nat Rev Clin Oncol 15(7):459\u2013466. https:\/\/doi.org\/10.1038\/s41571-018-0004-4","journal-title":"Nat Rev Clin Oncol"},{"issue":"39","key":"4482_CR18","doi-asserted-by":"publisher","first-page":"5484","DOI":"10.1038\/onc.2017.156","volume":"36","author":"TF Kuo","year":"2017","unstructured":"Kuo TF, Chen TY, Jiang ST, Chen KW, Chiang YM, Hsu YJ, Liu YJ, Chen HM, Yokoyama KK, Tsai KC, Yeh HH, Chen YR, Yang MT, Yang CY, Yang WC (2017) Protein disulfide isomerase a4 acts as a novel regulator of cancer growth through the procaspase pathway. Oncogene 36(39):5484\u20135496. https:\/\/doi.org\/10.1038\/onc.2017.156","journal-title":"Oncogene"},{"issue":"4","key":"4482_CR19","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1016\/j.cell.2018.01.029","volume":"172","author":"SA Lambert","year":"2018","unstructured":"Lambert SA, Jolma A, Campitelli LF, Das PK, Yin Y, Albu M, Chen X, Taipale J, Hughes TR, Weirauch MT (2018) The human transcription factors. Cell 172(4):650\u2013665. https:\/\/doi.org\/10.1016\/j.cell.2018.01.029","journal-title":"Cell"},{"issue":"2","key":"4482_CR20","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1056\/NEJMoa1505917","volume":"374","author":"WM Linehan","year":"2016","unstructured":"Linehan WM, Spellman PT, Ricketts CJ, Creighton CJ, Fei SS, Davis C, Wheeler DA, Murray BA, Schmidt L, Vocke CD, Peto M, Al Mamun AA, Shinbrot E, Sethi A, Brooks S, Rathmell WK, Brooks AN, Hoadley KA, Robertson AG, Brooks D, Bowlby R, Sadeghi S, Shen H, Weisenberger DJ, Bootwalla M, Baylin SB, Laird PW, Cherniack AD, Saksena G, Haake S, Li J, Liang H, Lu Y, Mills GB, Akbani R, Leiserson MD, Raphael BJ, Anur P, Bottaro D, Albiges L, Barnabas N, Choueiri TK, Czerniak B, Godwin AK, Hakimi AA, Ho TH, Hsieh J, Ittmann M, Kim WY, Krishnan B, Merino MJ, Mills Shaw KR, Reuter VE, Reznik E, Shelley CS, Shuch B, Signoretti S, Srinivasan R, Tamboli P, Thomas G, Tickoo S, Burnett K, Crain D, Gardner J, Lau K, Mallery D, Morris S, Paulauskis JD, Penny RJ, Shelton C, Shelton WT, Sherman M, Thompson E, Yena P, Avedon MT, Bowen J, Gastier-Foster JM, Gerken M, Leraas KM, Lichtenberg TM, Ramirez NC, Santos T, Wise L, Zmuda E, Demchok JA, Felau I, Hutter CM, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Zhang J, Ayala B, Baboud J, Chudamani S, Liu J, Lolla L, Naresh R, Pihl T, Sun Q, Wan Y, Wu Y, Ally A, Balasundaram M, Balu S, Beroukhim R, Bodenheimer T, Buhay C, Butterfield YS, Carlsen R, Carter SL, Chao H, Chuah E, Clarke A, Covington KR, Dahdouli M, Dewal N, Dhalla N, Doddapaneni HV, Drummond JA, Gabriel SB, Gibbs RA, Guin R, Hale W, Hawes A, Hayes DN, Holt RA, Hoyle AP, Jefferys SR, Jones SJ, Jones CD, Kalra D, Kovar C, Lewis L, Li J, Ma Y, Marra MA, Mayo M, Meng S, Meyerson M, Mieczkowski PA, Moore RA, Morton D, Mose LE, Mungall AJ, Muzny D, Parker JS, Perou CM, Roach J, Schein JE, Schumacher SE, Shi Y, Simons JV, Sipahimalani P, Skelly T, Soloway MG, Sougnez C, Tam A, Tan D, Thiessen N, Veluvolu U, Wang M, Wilkerson MD, Wong T, Wu J, Xi L, Zhou J, Bedford J, Chen F, Fu Y, Gerstein M, Haussler D, Kasaian K, Lai P, Ling S, Radenbaugh A, Van Den Berg D, Weinstein JN, Zhu J, Albert M, Alexopoulou I, Andersen JJ, Auman JT, Bartlett J, Bastacky S, Bergsten J, Blute ML, Boice L, Bollag RJ, Boyd J, Castle E, Chen YB, Cheville JC, Curley E, Davies B, DeVolk A, Dhir R, Dike L, Eckman J, Engel J, Harr J, Hrebinko R, Huang M, Huelsenbeck-Dill L, Iacocca M, Jacobs B, Lobis M, Maranchie JK, McMeekin S, Myers J, Nelson J, Parfitt J, Parwani A, Petrelli N, Rabeno B, Roy S, Salner AL, Slaton J, Stanton M, Thompson RH, Thorne L, Tucker K, Weinberger PM, Winemiller C, Zach LA, Zuna R (2016) Comprehensive molecular characterization of papillary renal-cell carcinoma. N Engl J Med 374(2):135\u2013145. https:\/\/doi.org\/10.1056\/NEJMoa1505917","journal-title":"N Engl J Med"},{"issue":"7","key":"4482_CR21","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1038\/s41419-020-2713-8","volume":"11","author":"Y Liu","year":"2020","unstructured":"Liu Y, Cheng G, Huang Z, Bao L, Liu J, Wang C, Xiong Z, Zhou L, Xu T, Liu D, Yang H, Chen K, Zhang X (2020) Long noncoding RNA SNHG12 promotes tumour progression and sunitinib resistance by upregulating CDCA3 in renal cell carcinoma. Cell Death Dis 11(7):515. https:\/\/doi.org\/10.1038\/s41419-020-2713-8","journal-title":"Cell Death Dis"},{"issue":"19","key":"4482_CR22","doi-asserted-by":"publisher","first-page":"10019","DOI":"10.1093\/nar\/gky679","volume":"46","author":"J Lu","year":"2018","unstructured":"Lu J, Xu J, Li J, Pan T, Bai J, Wang L, Jin X, Lin X, Zhang Y, Li Y, Sahni N, Li X (2018) FACER: comprehensive molecular and functional characterization of epigenetic chromatin regulators. Nucleic Acids Res 46(19):10019\u201310033. https:\/\/doi.org\/10.1093\/nar\/gky679","journal-title":"Nucleic Acids Res"},{"issue":"7","key":"4482_CR23","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1158\/2326-6066.Cir-17-0475","volume":"6","author":"RR McKay","year":"2018","unstructured":"McKay RR, Boss\u00e9 D, Xie W, Wankowicz SAM, Flaifel A, Brandao R, Lalani AA, Martini DJ, Wei XX, Braun DA, Van Allen E, Castellano D, De Velasco G, Wells JC, Heng DY, Fay AP, Schutz FA, Hsu J, Pal SK, Lee JL, Hsieh JJ, Harshman LC, Signoretti S, Motzer RJ, Feldman D, Choueiri TK (2018) The clinical activity of PD-1\/PD-L1 inhibitors in metastatic non-clear cell renal cell carcinoma. Cancer Immunol Res 6(7):758\u2013765. https:\/\/doi.org\/10.1158\/2326-6066.Cir-17-0475","journal-title":"Cancer Immunol Res"},{"issue":"6","key":"4482_CR24","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.urolonc.2021.04.013","volume":"39","author":"N Mendhiratta","year":"2021","unstructured":"Mendhiratta N, Muraki P, Sisk AE Jr, Shuch B (2021) Papillary renal cell carcinoma: review. Urol Oncol 39(6):327\u2013337. https:\/\/doi.org\/10.1016\/j.urolonc.2021.04.013","journal-title":"Urol Oncol"},{"issue":"5","key":"4482_CR25","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1038\/nmeth.3337","volume":"12","author":"AM Newman","year":"2015","unstructured":"Newman AM, Liu CL, Green MR, Gentles AJ, Feng W, Xu Y, Hoang CD, Diehn M, Alizadeh AA (2015) Robust enumeration of cell subsets from tissue expression profiles. Nat Methods 12(5):453\u2013457. https:\/\/doi.org\/10.1038\/nmeth.3337","journal-title":"Nat Methods"},{"issue":"6","key":"4482_CR26","doi-asserted-by":"publisher","first-page":"259.e251","DOI":"10.1016\/j.urolonc.2016.01.005","volume":"34","author":"DP Nguyen","year":"2016","unstructured":"Nguyen DP, Vertosick EA, Corradi RB, Vilaseca A, Benfante NE, Touijer KA, Sjoberg DD, Russo P (2016) Histological subtype of renal cell carcinoma significantly affects survival in the era of partial nephrectomy. Urol Oncol 34(6):259.e251\u2013258. https:\/\/doi.org\/10.1016\/j.urolonc.2016.01.005","journal-title":"Urol Oncol"},{"issue":"6","key":"4482_CR27","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1038\/onc.2011.266","volume":"31","author":"X Niu","year":"2012","unstructured":"Niu X, Zhang T, Liao L, Zhou L, Lindner DJ, Zhou M, Rini B, Yan Q, Yang H (2012) The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C. Oncogene 31(6):776\u2013786. https:\/\/doi.org\/10.1038\/onc.2011.266","journal-title":"Oncogene"},{"issue":"4","key":"4482_CR28","doi-asserted-by":"publisher","first-page":"842","DOI":"10.1038\/s41423-020-00565-9","volume":"18","author":"ST Paijens","year":"2021","unstructured":"Paijens ST, Vledder A, de Bruyn M, Nijman HW (2021) Tumor-infiltrating lymphocytes in the immunotherapy era. Cell Mol Immunol 18(4):842\u2013859. https:\/\/doi.org\/10.1038\/s41423-020-00565-9","journal-title":"Cell Mol Immunol"},{"issue":"4","key":"4482_CR29","doi-asserted-by":"publisher","first-page":"1793","DOI":"10.1016\/j.jtcvs.2017.12.107","volume":"155","author":"SY Park","year":"2018","unstructured":"Park SY (2018) Nomogram: an analogue tool to deliver digital knowledge. J Thorac Cardiovasc Surg 155(4):1793. https:\/\/doi.org\/10.1016\/j.jtcvs.2017.12.107","journal-title":"J Thorac Cardiovasc Surg"},{"key":"4482_CR30","doi-asserted-by":"publisher","first-page":"784","DOI":"10.3389\/fimmu.2020.00784","volume":"11","author":"F Petitprez","year":"2020","unstructured":"Petitprez F, Meylan M, de Reyni\u00e8s A, Saut\u00e8s-Fridman C, Fridman WH (2020) The tumor microenvironment in the response to immune checkpoint blockade therapies. Front Immunol 11:784. https:\/\/doi.org\/10.3389\/fimmu.2020.00784","journal-title":"Front Immunol"},{"issue":"11","key":"4482_CR31","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1038\/nrg3554","volume":"14","author":"C Plass","year":"2013","unstructured":"Plass C, Pfister SM, Lindroth AM, Bogatyrova O, Claus R, Lichter P (2013) Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer. Nat Rev Genet 14(11):765\u2013780. https:\/\/doi.org\/10.1038\/nrg3554","journal-title":"Nat Rev Genet"},{"issue":"1","key":"4482_CR32","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.celrep.2018.03.075","volume":"23","author":"CJ Ricketts","year":"2018","unstructured":"Ricketts CJ, De Cubas AA, Fan H, Smith CC, Lang M, Reznik E, Bowlby R, Gibb EA, Akbani R, Beroukhim R, Bottaro DP, Choueiri TK, Gibbs RA, Godwin AK, Haake S, Hakimi AA, Henske EP, Hsieh JJ, Ho TH, Kanchi RS, Krishnan B, Kwiatkowski DJ, Lui W, Merino MJ, Mills GB, Myers J, Nickerson ML, Reuter VE, Schmidt LS, Shelley CS, Shen H, Shuch B, Signoretti S, Srinivasan R, Tamboli P, Thomas G, Vincent BG, Vocke CD, Wheeler DA, Yang L, Kim WY, Robertson AG, Spellman PT, Rathmell WK, Linehan WM (2018) The cancer genome atlas comprehensive molecular characterization of renal cell carcinoma. Cell Rep 23(1):313-326.e315. https:\/\/doi.org\/10.1016\/j.celrep.2018.03.075","journal-title":"Cell Rep"},{"issue":"7","key":"4482_CR33","doi-asserted-by":"publisher","first-page":"e47","DOI":"10.1093\/nar\/gkv007","volume":"43","author":"ME Ritchie","year":"2015","unstructured":"Ritchie ME, Phipson B, Wu D, Hu Y, Law CW, Shi W, Smyth GK (2015) limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res 43(7):e47. https:\/\/doi.org\/10.1093\/nar\/gkv007","journal-title":"Nucleic Acids Res"},{"issue":"11","key":"4482_CR34","doi-asserted-by":"publisher","first-page":"2617","DOI":"10.1002\/cncr.22340","volume":"107","author":"EA Ronnen","year":"2006","unstructured":"Ronnen EA, Kondagunta GV, Ishill N, Spodek L, Russo P, Reuter V, Bacik J, Motzer RJ (2006) Treatment outcome for metastatic papillary renal cell carcinoma patients. Cancer 107(11):2617\u20132621. https:\/\/doi.org\/10.1002\/cncr.22340","journal-title":"Cancer"},{"issue":"1\u20132","key":"4482_CR35","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.cell.2014.12.033","volume":"160","author":"MS Rooney","year":"2015","unstructured":"Rooney MS, Shukla SA, Wu CJ, Getz G, Hacohen N (2015) Molecular and genetic properties of tumors associated with local immune cytolytic activity. Cell 160(1\u20132):48\u201361. https:\/\/doi.org\/10.1016\/j.cell.2014.12.033","journal-title":"Cell"},{"key":"4482_CR36","doi-asserted-by":"publisher","first-page":"632581","DOI":"10.3389\/fimmu.2021.632581","volume":"12","author":"S Schreiber","year":"2021","unstructured":"Schreiber S, Hammers CM, Kaasch AJ, Schraven B, Dudeck A, Kahlfuss S (2021) Metabolic interdependency of Th2 cell-mediated type 2 immunity and the tumor microenvironment. Front Immunol 12:632581. https:\/\/doi.org\/10.3389\/fimmu.2021.632581","journal-title":"Front Immunol"},{"issue":"5","key":"4482_CR37","doi-asserted-by":"publisher","first-page":"2132","DOI":"10.1016\/j.juro.2009.07.019","volume":"182","author":"PE Teloken","year":"2009","unstructured":"Teloken PE, Thompson RH, Tickoo SK, Cronin A, Savage C, Reuter VE, Russo P (2009) Prognostic impact of histological subtype on surgically treated localized renal cell carcinoma. J Urol 182(5):2132\u20132136. https:\/\/doi.org\/10.1016\/j.juro.2009.07.019","journal-title":"J Urol"},{"key":"4482_CR38","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13071653","author":"X Terra","year":"2021","unstructured":"Terra X, Ceperuelo-Mallafr\u00e9 V, Merma C, Benaiges E, Bosch R, Castillo P, Flores JC, Le\u00f3n X, Valduvieco I, Bast\u00e9 N, C\u00e1mara M, Lejeune M, Gum\u00e0 J, Vendrell J, Vilaseca I, Fern\u00e1ndez-Veledo S, Avil\u00e9s-Jurado FX (2021) Succinate pathway in head and neck squamous cell carcinoma: potential as a diagnostic and prognostic marker. Cancers (basel). https:\/\/doi.org\/10.3390\/cancers13071653","journal-title":"Cancers (basel)"},{"issue":"2","key":"4482_CR39","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1038\/s41556-018-0258-1","volume":"21","author":"AM Valencia","year":"2019","unstructured":"Valencia AM, Kadoch C (2019) Chromatin regulatory mechanisms and therapeutic opportunities in cancer. Nat Cell Biol 21(2):152\u2013161. https:\/\/doi.org\/10.1038\/s41556-018-0258-1","journal-title":"Nat Cell Biol"},{"key":"4482_CR40","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt1151","author":"Q Wang","year":"2014","unstructured":"Wang Q, Huang J, Sun H, Liu J, Wang J, Wang Q, Qin Q, Mei S, Zhao C, Yang X, Liu XS, Zhang Y (2014) CR Cistrome: a ChIP-Seq database for chromatin regulators and histone modification linkages in human and mouse. Nucleic Acids Res. https:\/\/doi.org\/10.1093\/nar\/gkt1151","journal-title":"Nucleic Acids Res"},{"issue":"12","key":"4482_CR41","doi-asserted-by":"publisher","first-page":"1572","DOI":"10.1093\/bioinformatics\/btq170","volume":"26","author":"MD Wilkerson","year":"2010","unstructured":"Wilkerson MD, Hayes DN (2010) ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking. Bioinformatics 26(12):1572\u20131573. https:\/\/doi.org\/10.1093\/bioinformatics\/btq170","journal-title":"Bioinformatics"},{"key":"4482_CR42","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1146\/annurev.biochem.67.1.545","volume":"67","author":"JL Workman","year":"1998","unstructured":"Workman JL, Kingston RE (1998) Alteration of nucleosome structure as a mechanism of transcriptional regulation. Annu Rev Biochem 67:545\u2013579. https:\/\/doi.org\/10.1146\/annurev.biochem.67.1.545","journal-title":"Annu Rev Biochem"},{"key":"4482_CR43","doi-asserted-by":"publisher","first-page":"4632453","DOI":"10.1155\/2022\/4632453","volume":"2022","author":"Y Xu","year":"2022","unstructured":"Xu Y, Shen M, Peng Y, Liu L, Tang L, Yang T, Pu D, Tan W, Zhang W, Liu S (2022) Cell division cycle-associated protein 3 (CDCA3) is a potential biomarker for clinical prognosis and immunotherapy in pan-cancer. Biomed Res Int 2022:4632453. https:\/\/doi.org\/10.1155\/2022\/4632453","journal-title":"Biomed Res Int"},{"issue":"3","key":"4482_CR44","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1016\/s0022-5347(17)35015-2","volume":"151","author":"B Zbar","year":"1994","unstructured":"Zbar B, Tory K, Merino M, Schmidt L, Glenn G, Choyke P, Walther MM, Lerman M, Linehan WM (1994) \u201cHereditary papillary renal cell carcinoma.\u201d J Urol 151(3):561\u2013566. https:\/\/doi.org\/10.1016\/s0022-5347(17)35015-2","journal-title":"J Urol"},{"issue":"7882","key":"4482_CR45","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1038\/s41586-021-03994-2","volume":"598","author":"SM Zhang","year":"2021","unstructured":"Zhang SM, Cai WL, Liu X, Thakral D, Luo J, Chan LH, McGeary MK, Song E, Blenman KRM, Micevic G, Jessel S, Zhang Y, Yin M, Booth CJ, Jilaveanu LB, Damsky W, Sznol M, Kluger HM, Iwasaki A, Bosenberg MW, Yan Q (2021) KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements. Nature 598(7882):682\u2013687. https:\/\/doi.org\/10.1038\/s41586-021-03994-2","journal-title":"Nature"},{"key":"4482_CR46","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1146\/annurev-immunol-030409-101212","volume":"28","author":"J Zhu","year":"2010","unstructured":"Zhu J, Yamane H, Paul WE (2010) Differentiation of effector CD4 T cell populations (*). Annu Rev Immunol 28:445\u2013489. https:\/\/doi.org\/10.1146\/annurev-immunol-030409-101212","journal-title":"Annu Rev Immunol"},{"issue":"1","key":"4482_CR47","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/s41065-021-00212-x","volume":"159","author":"K Zhu","year":"2022","unstructured":"Zhu K, Liu X, Deng W, Wang G, Fu B (2022) Identification of a chromatin regulator signature and potential candidate drugs for bladder cancer. Hereditas 159(1):13. https:\/\/doi.org\/10.1186\/s41065-021-00212-x","journal-title":"Hereditas"}],"container-title":["Journal of Cancer Research and Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00432-022-04482-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00432-022-04482-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00432-022-04482-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T07:38:44Z","timestamp":1675150724000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00432-022-04482-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,20]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["4482"],"URL":"https:\/\/doi.org\/10.1007\/s00432-022-04482-4","relation":{},"ISSN":["0171-5216","1432-1335"],"issn-type":[{"value":"0171-5216","type":"print"},{"value":"1432-1335","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,20]]},"assertion":[{"value":"20 September 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 November 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 November 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no potential conflicts of interesting.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}