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Protocadherin 10 plays a critical role in the central nervous system including in cell adhesion, formation and maintenance of neural circuits and synapses, regulation of actin assembly, cognitive function and tumor suppression. Additionally, Pcdh10 can serve as a non-invasive diagnostic and prognostic indicator for various cancers.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This paper collects and reviews relevant literature in Pubmed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This review describes the latest research understanding the role of Pcdh10 in neurological disease and human cancer, highlighting the importance of scrutinizing its properties for the development of targeted therapies and identifying a need for further research to explore Pcdh10 functions in other pathways, cell types and human pathologies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00432-023-04743-w","type":"journal-article","created":{"date-parts":[[2023,4,14]],"date-time":"2023-04-14T11:02:11Z","timestamp":1681470131000},"page":"8153-8164","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["The role of Pcdh10 in neurological disease and cancer"],"prefix":"10.1007","volume":"149","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9357-8375","authenticated-orcid":false,"given":"Yilan","family":"Zhen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Macarena","family":"Pavez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0751-6929","authenticated-orcid":false,"given":"Xinying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,4,14]]},"reference":[{"issue":"3","key":"4743_CR1","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1016\/s0306-4522(02)00944-2","volume":"117","author":"E Aoki","year":"2003","unstructured":"Aoki E, Kimura R, Suzuki ST, Hirano S (2003) Distribution of OL-protocadherin protein in correlation with specific neural compartments and local circuits in the postnatal mouse brain. 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