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Half of the irradiated area was covered with CSMed<jats:sup>\u00ae<\/jats:sup>and the other half was under routine treatment. The severity of radiation dermatitis was evaluated with radiation therapy oncology group (RTOG) grade throughout the treatment and the follow-up period. The RTOG grade between the dressed and undressed area were compared to illustrate the therapeutic effect of CSMed<jats:sup>\u00ae<\/jats:sup>dressing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The results showed that CSMed<jats:sup>\u00ae<\/jats:sup>dressed area had significant lower RTOG score at 3\u20137\u00a0weeks and final record during the treatment, and 1\u20133\u00a0weeks during follow-up than undressed area.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This indicated that CSMed<jats:sup>\u00ae<\/jats:sup>can delay the onset, reduce the severity, and enhance healing of radiation dermatitis. CSMed<jats:sup>\u00ae<\/jats:sup>can be used for prophylaxis and management of radiation dermatitis.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00432-024-05624-6","type":"journal-article","created":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T13:02:29Z","timestamp":1708693349000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["CSMed\u00ae wound dressing for prophylaxis and management of radiation dermatitis in breast and head\u2013neck cancer patients: a single hospital prospective clinical trial"],"prefix":"10.1007","volume":"150","author":[{"given":"Yueh-Chun","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsien-Chun","family":"Tseng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huei-Fang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Hung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Fang","family":"Ko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin-Tsung","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsin-Lin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo-Jiun","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Hsiang","family":"Chou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,2,23]]},"reference":[{"issue":"6","key":"5624_CR1","doi-asserted-by":"publisher","first-page":"3266","DOI":"10.3390\/ijerph19063266","volume":"19","author":"E Arribas-L\u00f3pez","year":"2022","unstructured":"Arribas-L\u00f3pez E, Zand N, Ojo O, Snowden MJ, Kochhar T (2022) A systematic review of the effect of Centella asiatica on wound healing. 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