{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:52:18Z","timestamp":1791071538723,"version":"4.1.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T00:00:00Z","timestamp":1790985600000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cancer Res Clin Oncol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Recipients of allogeneic haematopoietic stem cell transplantation (alloHSCT) are at increased risk of COVID-19 and lower vaccine immunogenicity. This study assessed vaccine immunogenicity and safety in these patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed the serological response after the 2nd\u00a0and 3rd SARS-CoV-2 vaccination as well as potential factors influencing this response. Data were obtained from internal hospital records. In addition, a questionnaire was used to evaluate the vaccination status, vaccination side effects and the course of expired COVID-19 disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 114 patients (median age 62, range 27 \u2013 70) were enrolled between July and September 2022, with 55 females (48.2%). One year later a follow up was conducted. Most patients (89.4%) were vaccinated at least twice, 66.7% received three vaccinations, and 10.5% refused the vaccination. The mRNA vaccines were predominantly used. Most patients responded and reached SARS-CoV-2 spike IgG titers after the 2nd\u00a0(81.8%) or 3rd\u00a0(96.1%) vaccination. Patients vaccinated within 24\u00a0months of alloHSCT had significantly lower anti-spike IgG levels than those vaccinated later (\n                      <jats:italic>p<\/jats:italic>\n                      =0.017). Common side effects included arm pain (34%), swelling (14%), and limb pain (17%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Vaccination was feasible and well-tolerated in alloHSCT recipients. Timing of vaccination influenced immune response, with a stronger response after the 3rd dose compared to the initial series.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00432-026-06632-4","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T16:55:46Z","timestamp":1790873746000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Longer-term response to SARS-CoV-2 vaccination after allogeneic blood stem cell transplantation"],"prefix":"10.1007","volume":"152","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2160-1452","authenticated-orcid":false,"given":"Carl C.","family":"Crodel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Gork","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wibke","family":"G\u00f6pel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Linke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konrad","family":"Sinn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny","family":"Miethke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Hochhaus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inken","family":"Hilgendorf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,1]]},"reference":[{"issue":"12","key":"6632_CR1","doi-asserted-by":"publisher","first-page":"9687","DOI":"10.1007\/s00520-022-07376-w","volume":"30","author":"N Albiol","year":"2022","unstructured":"Albiol N, Aso O, G\u00f3mez-P\u00e9rez L, Triquell M, Roch N, L\u00e1zaro E, Esquirol A, Gonz\u00e1lez I, L\u00f3pez-Contreras J, Sierra J, Martino R, Garc\u00eda-Cadenas I (2022) Mrna-1273 Sars-Cov-2 vaccine safety and Covid-19 risk perception in recently transplanted allogeneic hematopoietic stem cell transplant recipients. Support Care Cancer 30(12):9687\u20139690. https:\/\/doi.org\/10.1007\/s00520-022-07376-w","journal-title":"Support Care Cancer"},{"issue":"11","key":"6632_CR2","doi-asserted-by":"publisher","first-page":"938.e1","DOI":"10.1016\/j.jtct.2021.07.008","volume":"27","author":"H Ali","year":"2021","unstructured":"Ali H, Ngo D, Aribi A, Arslan S, Dadwal S, Marcucci G, Nakamura R, Forman SJ, Chen J, Al Malki MM (2021) Safety and tolerability of Sars-Cov2 emergency-use authorized vaccines for allogeneic hematopoietic stem cell transplant recipients. Transplant Cell Ther 27(11):938.e1-938.e6. https:\/\/doi.org\/10.1016\/j.jtct.2021.07.008","journal-title":"Transplant Cell Ther"},{"issue":"2","key":"6632_CR3","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1097\/TP.0b013e3181772a75","volume":"86","author":"G Avetisyan","year":"2008","unstructured":"Avetisyan G, Aschan J, Hassan M, Ljungman P (2008) Evaluation of immune responses to seasonal influenza vaccination in healthy volunteers and in patients after stem cell transplantation. Transplantation 86(2):257\u2013263. https:\/\/doi.org\/10.1097\/TP.0b013e3181772a75","journal-title":"Transplantation"},{"issue":"3","key":"6632_CR4","doi-asserted-by":"publisher","DOI":"10.1111\/tid.13828","volume":"24","author":"A Beerlage","year":"2022","unstructured":"Beerlage A, Leuzinger K, Valore L, Mathew R, Junker T, Drexler B, Passweg JR, Hirsch HH, Halter J (2022) Antibody response to Mrna Sars-Cov-2 vaccination in 182 patients after allogeneic hematopoietic cell transplantation. Transpl Infect Dis 24(3):e13828. https:\/\/doi.org\/10.1111\/tid.13828","journal-title":"Transpl Infect Dis"},{"issue":"1","key":"6632_CR5","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-021-01190-3","volume":"14","author":"L Canti","year":"2021","unstructured":"Canti L, Humblet-Baron S, Desombere I, Neumann J, Pannus P, Heyndrickx L, Henry A, Servais S, Willems E, Ehx G, Goriely S, Seidel L, Michiels J, Willems B, Liston A, Ari\u00ebn KK, Beguin Y, Goossens ME, Marchant A, Baron F (2021) Predictors of neutralizing antibody response to Bnt162b2 vaccination in allogeneic hematopoietic stem cell transplant recipients. J Hematol Oncol 14(1):174. https:\/\/doi.org\/10.1186\/s13045-021-01190-3","journal-title":"J Hematol Oncol"},{"issue":"5","key":"6632_CR6","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1002\/hon.3006","volume":"40","author":"P Chevallier","year":"2022","unstructured":"Chevallier P, Jullien M, Peterlin P, Garnier A, Le Bourgeois A, Coste-Burel M, B\u00e9n\u00e9 MC, Guillaume T (2022) Effectiveness of a third dose of Bnt162b2 anti-Sars-Cov-2 Mrna vaccine over a 6-month follow-up period in allogenic hematopoietic stem cells recipients. Hematol Oncol 40(5):1097\u20131099. https:\/\/doi.org\/10.1002\/hon.3006","journal-title":"Hematol Oncol"},{"issue":"11","key":"6632_CR7","doi-asserted-by":"publisher","first-page":"2025","DOI":"10.1038\/s41591-021-01527-y","volume":"27","author":"A Choi","year":"2021","unstructured":"Choi A, Koch M, Wu K, Chu L, Ma L, Hill A, Nunna N, Huang W, Oestreicher J, Colpitts T, Bennett H, Legault H, Paila Y, Nestorova B, Ding B, Montefiori D, Pajon R, Miller JM, Leav B, Carfi A, McPhee R, Edwards DK (2021) Safety and immunogenicity of Sars-Cov-2 variant Mrna vaccine boosters in healthy adults: an interim analysis. Nat Med 27(11):2025\u20132031. https:\/\/doi.org\/10.1038\/s41591-021-01527-y","journal-title":"Nat Med"},{"issue":"1","key":"6632_CR8","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1097\/01.tp.0000225762.54757.f7","volume":"82","author":"C Cordonnier","year":"2006","unstructured":"Cordonnier C, Maury S, Ribaud P, Kuentz M, Bassompierre F, Gluckman E, Chevret S (2006) A grading system based on severity of infection to predict mortality in allogeneic stem cell transplant recipients. Transplantation 82(1):86\u201392. https:\/\/doi.org\/10.1097\/01.tp.0000225762.54757.f7","journal-title":"Transplantation"},{"key":"6632_CR9","doi-asserted-by":"publisher","DOI":"10.1038\/s41409-021-01561-x","author":"LE Daudt","year":"2022","unstructured":"Daudt LE, Corso MCM, Kerbauy MN, de Assis LHDS, Rechenmacher C, Colturato I, Machado CM (2022) Covid-19 in Hsct recipients: A collaborative study of the brazilian society of marrow transplantation (Sbtmo). Bone Marrow. https:\/\/doi.org\/10.1038\/s41409-021-01561-x","journal-title":"Bone Marrow"},{"issue":"5","key":"6632_CR39","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/j.vaccine.2013.11.073","volume":"32","author":"N Le Dh\u00e9din","year":"2014","unstructured":"Dh\u00e9din N, Krivine A, Le Corre N, Mallet A, Lioure B, Bay JO, Rubio MT, Agape P, Thi\u00e9baut A, Le Goff J, Autran B, Ribaud P (2014) Comparable humoral response after two doses of adjuvanted influenza A\/H1N1pdm2009 vaccine or natural infection in allogeneic stem cell transplant recipients. Vaccine 32(5):585\u2013591. https:\/\/doi.org\/10.1016\/j.vaccine.2013.11.073","journal-title":"Vaccine"},{"issue":"17","key":"6632_CR10","doi-asserted-by":"publisher","first-page":"1627","DOI":"10.1056\/NEJMc2113468","volume":"385","author":"AR Falsey","year":"2022","unstructured":"Falsey AR, Frenck RW, Walsh EE, Kitchin N, Absalon J, Gurtman A, Lockhart S, Bailey R, Swanson KA, Xu X, Koury K, Kalina W, Cooper D, Zou J, Xie X, Xia H, T\u00fcreci \u00d6, Lagkadinou E, Tompkins KR, Shi PY, Jansen KU, \u015eahin U, Dormitzer PR, Gruber WC (2022) Sars-Cov-2 neutralization with Bnt162b2 vaccine dose 3. N Engl J Med 385(17):1627\u20131629. https:\/\/doi.org\/10.1056\/NEJMc2113468","journal-title":"N Engl J Med"},{"issue":"1","key":"6632_CR11","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1186\/s40164-022-00299-6","volume":"11","author":"C Ge","year":"2022","unstructured":"Ge C, Du K, Luo M, Shen K, Zhou Y, Guo K, Chen X (2022) Serologic Response and Safety of Covid-19 Vaccination in Hsct or Car T-Cell Recipients: A Systematic Review and Meta-Analysis. Exp Hematol Oncol 11(1):46. https:\/\/doi.org\/10.1186\/s40164-022-00299-6","journal-title":"Exp Hematol Oncol"},{"issue":"2","key":"6632_CR12","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.medj.2022.01.001","volume":"3","author":"K Healy","year":"2022","unstructured":"Healy K, Pin E, Chen P, S\u00f6derdahl G, Nowak P, Mielke S, Hansson L, Bergman P, Smith CIE, Ljungman P, Valentini D, Blennow O, \u00d6sterborg A, Gabarrini G, Al-Manei K, Alkharaan H, Sobkowiak MJ, Yousef J, Mravinacova S, Cuapio A, Xu X, Akber M, Lor\u00e9 K, Hellstr\u00f6m C, Muschiol S, Bogdanovic G, Buggert M, Ljunggren HG, Hober S, Nilsson P, Aleman S, S\u00e4llberg Chen M (2022) Salivary IgG to Sars-Cov-2 indicates seroconversion and correlates to serum neutralization in mRNA-vaccinated immunocompromised individuals. Med 3(2):137-153.e3. https:\/\/doi.org\/10.1016\/j.medj.2022.01.001","journal-title":"Med"},{"key":"6632_CR14","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1174289","volume":"14","author":"ML H\u00fctter-Kr\u00f6nke","year":"2023","unstructured":"H\u00fctter-Kr\u00f6nke ML, Neagoie A, Blau IW, Wais V, Vuong L, Gantner A, Ahn J, Penack O, Schnell J, Nogai KA, Ebersp\u00e4cher B, Saadati M, Benner A, Bullinger L, D\u00f6hner H, Bunjes D, Sala E (2023) Risk factors and characteristics influencing humoral response to Covid-19 vaccination in patients after allogeneic stem cell transplantation. Front Immunol 14:1174289. https:\/\/doi.org\/10.3389\/fimmu.2023.1174289","journal-title":"Front Immunol"},{"issue":"4","key":"6632_CR13","doi-asserted-by":"publisher","first-page":"214.e1","DOI":"10.1016\/j.jtct.2022.01.019","volume":"28","author":"A Huang","year":"2022","unstructured":"Huang A, Cicin-Sain C, Pasin C, Epp S, Audig\u00e9 A, M\u00fcller NJ, Nilsson J, Bankova A, Wolfensberger N, Vilinovszki O, Nair G, Hockl P, Schanz U, Kouyos RD, Hasse B, Zinkernagel AS, Trkola A, Manz MG, Abela IA, M\u00fcller AMS (2022) Antibody response to Sars-Cov-2 vaccination in patients following allogeneic hematopoietic cell transplantation. Transplant Cell Ther 28(4):214.e1-214.e11. https:\/\/doi.org\/10.1016\/j.jtct.2022.01.019","journal-title":"Transplant Cell Ther"},{"issue":"5","key":"6632_CR15","doi-asserted-by":"publisher","first-page":"279.e1","DOI":"10.1016\/j.jtct.2022.02.018","volume":"28","author":"M Jullien","year":"2022","unstructured":"Jullien M, Le Bourgeois A, Coste-Burel M, Peterlin P, Garnier A, Rimbert M, Imbert BM, Le Gouill S, Moreau P, Mahe B, Dubruille V, Blin N, Lok A, Touzeau C, Gastinne T, Tessoulin B, Vantyghem S, B\u00e9n\u00e9 MC, Guillaume T, Chevallier P (2022) B cell aplasia is the most powerful predictive marker for poor humoral response after BNT162b2 mRNA Sars-Cov-2 vaccination in recipients of allogeneic hematopoietic stem cell transplantation. Transplant Cell Ther 28(5):279.e1-279.e4. https:\/\/doi.org\/10.1016\/j.jtct.2022.02.018","journal-title":"Transplant Cell Ther"},{"issue":"645","key":"6632_CR16","doi-asserted-by":"publisher","first-page":"eabm2311","DOI":"10.1126\/scitranslmed.abm2311","volume":"14","author":"P de Kaplonek","year":"2022","unstructured":"Kaplonek P, Cizmeci D, Fischinger S, Collier AR, Suscovich T, Linde C, Broge T, Mann C, Amanat F, Dayal D, Rhee J, de St Aubin M, Nilles EJ, Musk ER, Menon AS, Saphire EO, Krammer F, Lauffenburger DA, Barouch DH, Alter G (2022) Mrna-1273 and Bnt162b2 Covid-19 Vaccines Elicit Antibodies with Differences in Fc-Mediated Effector Functions. Sci Transl Med 14(645):eabm2311. https:\/\/doi.org\/10.1126\/scitranslmed.abm2311","journal-title":"Sci Transl Med"},{"issue":"1","key":"6632_CR40","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.bbmt.2012.08.015","volume":"19","author":"NA Karras","year":"2013","unstructured":"Karras NA, Weeres M, Sessions W, Xu X, Defor T, Young JA, Stefanski H, Brunstein C, Cooley S, Miller JS, Blazar BR, Wagner JE, Verneris MR (2013) A randomized trial of one versus two doses of influenza vaccine after allogeneic transplantation. Biol Blood Marrow Transpl 19(1):109\u2013116. https:\/\/doi.org\/10.1016\/j.bbmt.2012.08.015","journal-title":"Biol Blood Marrow Transpl"},{"issue":"7","key":"6632_CR17","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofad349","volume":"10","author":"A Kokogho","year":"2023","unstructured":"Kokogho A, Crowell TA, Aleissa M, Lupan AM, Davey S, Park Chang JB, Baden LR, Walsh SR, Sherman AC (2023) Sars-CoV-2 vaccine-induced immune responses among hematopoietic stem cell transplant recipients. Open Forum Infect Dis 10(7):ofad349. https:\/\/doi.org\/10.1093\/ofid\/ofad349","journal-title":"Open Forum Infect Dis"},{"issue":"3","key":"6632_CR18","doi-asserted-by":"publisher","first-page":"e163","DOI":"10.1016\/S2352-3026(21)00008-9","volume":"8","author":"M Leclerc","year":"2021","unstructured":"Leclerc M, Maury S (2021) A rationale to prioritise vaccination of HSCT patients against COVID-19. Lancet Haematol 8(3):e163\u2013e164. https:\/\/doi.org\/10.1016\/S2352-3026(21)00008-9","journal-title":"Lancet Haematol"},{"key":"6632_CR19","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.965971","volume":"13","author":"Z Li","year":"2022","unstructured":"Li Z, Liu S, Li F, Li Y, Peng P, Li S, He L, Liu T (2022) Efficacy, immunogenicity and safety of Covid-19 vaccines in older adults: a systematic review and meta-analysis. Front Immunol 13:965971. https:\/\/doi.org\/10.3389\/fimmu.2022.965971","journal-title":"Front Immunol"},{"issue":"3","key":"6632_CR20","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/S1470-2045(20)30096-6","volume":"21","author":"W Liang","year":"2020","unstructured":"Liang W, Guan W, Chen R, Wang W, Li J, Xu K, Li C, Ai Q, Lu W, Liang H, Li S, He J (2020) Cancer patients in Sars-CoV-2 infection: a nationwide analysis in China. Lancet Oncol 21(3):335\u2013337. https:\/\/doi.org\/10.1016\/S1470-2045(20)30096-6","journal-title":"Lancet Oncol"},{"key":"6632_CR21","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9101075","author":"M Lindemann","year":"2021","unstructured":"Lindemann M, Klisanin V, Th\u00fcmmler L, Fisenkci N, Tsachakis-M\u00fcck N, Ditschkowski M, Schwarzkopf S, Klump H, Reinhardt HC, Horn PA, Koldehoff M (2021) Humoral and cellular vaccination responses against Sars-CoV-2 in hematopoietic stem cell transplant recipients. Vaccines (Basel). https:\/\/doi.org\/10.3390\/vaccines9101075","journal-title":"Vaccines (Basel)"},{"issue":"1","key":"6632_CR22","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1182\/hematology.2021000294","volume":"2021","author":"P Ljungman","year":"2021","unstructured":"Ljungman P (2021) Infectious complications and vaccines. Hematology Am Soc Hematol Educ Program 2021(1):587\u2013591. https:\/\/doi.org\/10.1182\/hematology.2021000294","journal-title":"Hematology Am Soc Hematol Educ Program"},{"issue":"6","key":"6632_CR23","doi-asserted-by":"publisher","DOI":"10.1016\/j.accpm.2021.100967","volume":"40","author":"P Loubet","year":"2021","unstructured":"Loubet P, Laureillard D, Martin A, Larcher R, Sotto A (2021) Why promoting a Covid-19 vaccine booster dose? Anaesth Crit Care Pain Med 40(6):100967. https:\/\/doi.org\/10.1016\/j.accpm.2021.100967","journal-title":"Anaesth Crit Care Pain Med"},{"key":"6632_CR24","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14020325","author":"M Majcherek","year":"2022","unstructured":"Majcherek M, Matkowska-Kocjan A, Szymczak D, Karasek M, Szeremet A, Kiraga A, Milanowska A, Kuznik E, Kujawa K, Wrobel T, Szenborn L, Czyz A (2022) Two doses of Bnt162b2 mRNA vaccine in patients after hematopoietic stem cell transplantation: humoral response and serological conversion predictors. Cancers (Basel). https:\/\/doi.org\/10.3390\/cancers14020325","journal-title":"Cancers (Basel)"},{"key":"6632_CR25","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9101209","author":"A Matkowska-Kocjan","year":"2021","unstructured":"Matkowska-Kocjan A, Owoc-Lempach J, Chruszcz J, Ku\u017anik E, Szenborn F, Jurczenko L, W\u00f3jcik M, Bany\u015b D, Szenborn L, Ussowicz M (2021) The Covid-19 mRNA Bnt163b2 vaccine was well tolerated and highly immunogenic in young adults in long follow-up after haematopoietic stem cell transplantation. Vaccines (Basel). https:\/\/doi.org\/10.3390\/vaccines9101209","journal-title":"Vaccines (Basel)"},{"key":"6632_CR26","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines10111782","author":"T Meyer","year":"2022","unstructured":"Meyer T, Ihorst G, Bartsch I, Zeiser R, W\u00e4sch R, Bertz H, Finke J, Huzly D, Wehr C (2022) Cellular and humoral Sars-Cov-2 vaccination responses in 192 adult recipients of allogeneic hematopoietic cell transplantation. Vaccines (Basel). https:\/\/doi.org\/10.3390\/vaccines10111782","journal-title":"Vaccines (Basel)"},{"issue":"9","key":"6632_CR27","doi-asserted-by":"publisher","first-page":"796.e1","DOI":"10.1016\/j.jtct.2021.07.005","volume":"27","author":"MU Mushtaq","year":"2021","unstructured":"Mushtaq MU, Shahzad M, Chaudhary SG, Luder M, Ahmed N, Abdelhakim H, Bansal R, Balusu R, DeJarnette S, Divine C, Kribs R, Shune L, Singh AK, Ganguly S, Abhyankar SH, McGuirk JP (2021) Impact of Sars-Cov-2 in hematopoietic stem cell transplantation and chimeric antigen receptor T cell therapy recipients. Transplant Cell Ther 27(9):796.e1-796.e7. https:\/\/doi.org\/10.1016\/j.jtct.2021.07.005","journal-title":"Transplant Cell Ther"},{"issue":"2","key":"6632_CR42","doi-asserted-by":"publisher","first-page":"330","DOI":"10.3390\/vaccines10020330","volume":"10","author":"C Pabst","year":"2022","unstructured":"Pabst C, Benning L, Liebers N, Janssen M, Caille L, Speer C, He L, Schubert ML, Simons L, Hegenbart U, Sch\u00f6nland S, Radujkovic A, Schmitt M, Schnitzler P, M\u00fcller-Tidow C, Dietrich S, Dreger P, Luft T (2022) Humoral Responses and Chronic GVHD Exacerbation after COVID-19 Vaccination Post Allogeneic Stem Cell Transplantation. Vaccines (Basel) 10(2):330. https:\/\/doi.org\/10.3390\/vaccines10020330","journal-title":"Vaccines (Basel)"},{"issue":"1","key":"6632_CR28","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1002\/ajh.26385","volume":"97","author":"JL Pi\u00f1ana","year":"2022","unstructured":"Pi\u00f1ana JL, L\u00f3pez-Corral L, Martino R, Montoro J, Vazquez L, P\u00e9rez A, Martin-Martin G, Facal-Malvar A, Ferrer E, Pascual MJ, Sanz-Linares G, Gago B, Sanchez-Salinas A, Villalon L, Conesa-Garcia V, Olave MT, L\u00f3pez-Jimenez J, Marcos-Corrales S, Garc\u00eda-Bl\u00e1zquez M, Garcia-Guti\u00e9rrez V, Hern\u00e1ndez-Rivas J, Saus A, Espigado I, Alonso C, Hernani R, Solano C, Ferrer-Lores B, Guerreiro M, Ruiz-Garc\u00eda M, Mu\u00f1oz-Bellido JL, Navarro D, Cedillo A, Sureda A, Infectious Complications Subcommittee of the Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group (GETH-TC) (2022) Sars-Cov-2-reactive antibody detection after Sars-Cov-2 vaccination in hematopoietic stem cell transplant recipients: prospective survey from the Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group. Am J Hematol 97(1):30\u201342. https:\/\/doi.org\/10.1002\/ajh.26385","journal-title":"Am J Hematol"},{"issue":"27","key":"6632_CR29","doi-asserted-by":"publisher","first-page":"2603","DOI":"10.1056\/NEJMoa2034577","volume":"383","author":"FP Polack","year":"2020","unstructured":"Polack FP, Thomas SJ, Kitchin N, Absalon J, Gurtman A, Lockhart S, Perez JL, P\u00e9rez Marc G, Moreira ED, Zerbini C, Bailey R, Swanson KA, Roychoudhury S, Koury K, Li P, Kalina WV, Cooper D, Frenck RW, Hammitt LL, T\u00fcreci \u00d6, Nell H, Schaefer A, \u00dcnal S, Tresnan DB, Mather S, Dormitzer PR, \u015eahin U, Jansen KU, Gruber WC, C4591001 Clinical Trial Group (2020) Safety and efficacy of the Bnt162b2 Mrna Covid-19 vaccine. N Engl J Med 383(27):2603\u20132615. https:\/\/doi.org\/10.1056\/NEJMoa2034577","journal-title":"N Engl J Med"},{"issue":"9","key":"6632_CR30","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1016\/j.jtct.2021.06.024","volume":"27","author":"R Ram","year":"2021","unstructured":"Ram R, Hagin D, Kikozashvilli N, Freund T, Amit O, Bar-On Y, Beyar-Katz O, Shefer G, Moshiashvili MM, Karni C, Gold R, Kay S, Glait-Santar C, Eshel R, Perry C, Avivi I, Apel A, Benyamini N, Shasha D, Ben-Ami R (2021) Safety and immunogenicity of the Bnt162b2 Mrna Covid-19 vaccine in patients after allogeneic Hct or Cd19-based Cart therapy-a single-center prospective cohort study. Transplant Cell Ther 27(9):788\u2013794. https:\/\/doi.org\/10.1016\/j.jtct.2021.06.024","journal-title":"Transplant Cell Ther"},{"issue":"10","key":"6632_CR31","doi-asserted-by":"publisher","first-page":"e681","DOI":"10.1016\/S2352-3026(21)00274-X","volume":"8","author":"R Redjoul","year":"2021","unstructured":"Redjoul R, Le Bouter A, Parinet V, Fourati S, Maury S (2021) Antibody response after third Bnt162b2 dose in recipients of allogeneic Hsct. Lancet Haematol 8(10):e681\u2013e683. https:\/\/doi.org\/10.1016\/S2352-3026(21)00274-X","journal-title":"Lancet Haematol"},{"issue":"6","key":"6632_CR32","doi-asserted-by":"publisher","first-page":"337.e1","DOI":"10.1016\/j.jtct.2022.03.010","volume":"28","author":"J Schaffrath","year":"2022","unstructured":"Schaffrath J, Brummer C, Wolff D, Holtick U, Kr\u00f6ger N, Bornh\u00e4user M, Kraus S, Hilgendorf I, Blau IW, Penack O, Wittke C, Steiner N, Nachbaur D, Thurner L, Hindahl H, Zeiser R, Maier CP, Bethge W, M\u00fcller LP (2022) High mortality of Covid-19 early after allogeneic stem cell transplantation: a retrospective multicenter analysis on behalf of the German Cooperative Transplant Study Group. Transplant Cell Ther 28(6):337.e1-337.e10. https:\/\/doi.org\/10.1016\/j.jtct.2022.03.010","journal-title":"Transplant Cell Ther"},{"issue":"4","key":"6632_CR33","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1111\/bjh.17955","volume":"196","author":"S Sengsayadeth","year":"2022","unstructured":"Sengsayadeth S, Broglie L, Savani BN (2022) Effectiveness of Covid-19 vaccination in patients after allogeneic haematopoietic cell transplant: how much protection are we getting? Br J Haematol 196(4):809\u2013811. https:\/\/doi.org\/10.1111\/bjh.17955","journal-title":"Br J Haematol"},{"issue":"3","key":"6632_CR34","doi-asserted-by":"publisher","first-page":"e185","DOI":"10.1016\/S2352-3026(20)30429-4","volume":"8","author":"A Sharma","year":"2021","unstructured":"Sharma A, Bhatt NS, St Martin A, Abid MB, Bloomquist J, Chemaly RF, Dandoy C, Gauthier J, Gowda L, Perales MA, Seropian S, Shaw BE, Tuschl EE, Zeidan AM, Riches ML, Shah GL (2021) Clinical characteristics and outcomes of Covid-19 in haematopoietic stem-cell transplantation recipients: an observational cohort study. Lancet Haematol 8(3):e185\u2013e193. https:\/\/doi.org\/10.1016\/S2352-3026(20)30429-4","journal-title":"Lancet Haematol"},{"issue":"4","key":"6632_CR35","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1111\/bjh.17918","volume":"196","author":"N Shem-Tov","year":"2022","unstructured":"Shem-Tov N, Yerushalmi R, Danylesko I, Litachevsky V, Levy I, Olmer L, Lusitg Y, Avigdor A, Nagler A, Shimoni A, Rahav G (2022) Immunogenicity and safety of the Bnt162b2 Mrna Covid-19 vaccine in haematopoietic stem cell transplantation recipients. Br J Haematol 196(4):884\u2013891. https:\/\/doi.org\/10.1111\/bjh.17918","journal-title":"Br J Haematol"},{"key":"6632_CR41","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1016\/S0140-6736(21)00432-3","volume":"397","author":"M Voysey","year":"2021","unstructured":"Voysey M, Costa Clemens S, Madhi S et al (2021) Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trialsThe. Lancet 397:881\u2013891. https:\/\/doi.org\/10.1016\/S0140-6736(21)00432-3","journal-title":"Lancet"},{"key":"6632_CR36","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines10020158","author":"M Watanabe","year":"2022","unstructured":"Watanabe M, Yakushijin K, Funakoshi Y, Ohji G, Hojo W, Sakai H, Saeki M, Hirakawa Y, Matsumoto S, Sakai R, Nagao S, Kitao A, Miyata Y, Koyama T, Saito Y, Kawamoto S, Ito M, Murayama T, Matsuoka H, Minami H (2022) The safety and immunogenicity of the Bnt162b2 Mrna Covid-19 vaccine in Japanese patients after allogeneic stem cell transplantation. Vaccines. https:\/\/doi.org\/10.3390\/vaccines10020158","journal-title":"Vaccines"},{"issue":"5","key":"6632_CR37","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/S2213-2600(20)30079-5","volume":"8","author":"X Yang","year":"2020","unstructured":"Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, Wu Y, Zhang L, Yu Z, Fang M, Yu T, Wang Y, Pan S, Zou X, Yuan S, Shang Y (2020) Clinical course and outcomes of critically ill patients with Sars-Cov-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med 8(5):475\u2013481. https:\/\/doi.org\/10.1016\/S2213-2600(20)30079-5","journal-title":"Lancet Respir Med"},{"issue":"2","key":"6632_CR38","doi-asserted-by":"publisher","first-page":"303.e1","DOI":"10.1016\/j.cmi.2021.10.007","volume":"28","author":"M Yeshurun","year":"2022","unstructured":"Yeshurun M, Pasvolsky O, Shargian L, Yahav D, Ben-Zvi H, Rubinstein M, Sela-Navon M, Wolach O, Raanani P, Rozovski U (2022) Humoral serological response to the Bnt162b2 vaccine after allogeneic haematopoietic cell transplantation. Clin Microbiol Infect 28(2):303.e1-303.e4. https:\/\/doi.org\/10.1016\/j.cmi.2021.10.007","journal-title":"Clin Microbiol Infect"}],"container-title":["Journal of Cancer Research and Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00432-026-06632-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00432-026-06632-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00432-026-06632-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:03:37Z","timestamp":1791068617000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00432-026-06632-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,1]]},"references-count":42,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2026,10]]}},"alternative-id":["6632"],"URL":"https:\/\/doi.org\/10.1007\/s00432-026-06632-4","relation":{},"ISSN":["1432-1335"],"issn-type":[{"value":"1432-1335","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,1]]},"assertion":[{"value":"16 July 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"IH received honoraria from Abbvie, Alexion, Medac, Mundipharma, Novartis and Takeda. AH received research support from Novartis, BMS, Pfizer, Incyte. The other authors do not declare any conflict of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"191"}}