{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T10:06:14Z","timestamp":1790762774339,"version":"4.1.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2008,8,5]],"date-time":"2008-08-05T00:00:00Z","timestamp":1217894400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitol Res"],"published-print":{"date-parts":[[2008,11]]},"DOI":"10.1007\/s00436-008-1133-y","type":"journal-article","created":{"date-parts":[[2008,8,4]],"date-time":"2008-08-04T00:04:42Z","timestamp":1217808282000},"page":"1303-1309","source":"Crossref","is-referenced-by-count":74,"title":["Efficacy of 2- and 4-week rifampicin treatment on the Wolbachia of Onchocerca volvulus"],"prefix":"10.1007","volume":"103","author":[{"given":"Sabine","family":"Specht","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Mand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeboah","family":"Marfo-Debrekyei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander Yaw","family":"Debrah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Konadu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ohene","family":"Adjei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dietrich W.","family":"B\u00fcttner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Achim","family":"Hoerauf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,8,5]]},"reference":[{"key":"1133_CR1","first-page":"331","volume":"39","author":"EJ Albiez","year":"1988","unstructured":"Albiez EJ, B\u00fcttner DW, Duke BO (1988) Diagnosis and extirpation of nodules in human onchocerciasis. Trop Med Parasitol 39:331\u2013346","journal-title":"Trop Med Parasitol"},{"key":"1133_CR2","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0035-9203(99)90305-X","volume":"93","author":"K Awadzi","year":"1999","unstructured":"Awadzi K, Attah SK, Addy ET, Opoku NO, Quartey BT (1999) The effects of high-dose ivermectin regimens on Onchocerca volvulus in onchocerciasis patients. Trans R Soc Trop Med Hyg 93:189\u2013194","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"1133_CR3","doi-asserted-by":"crossref","first-page":"e371","DOI":"10.1371\/journal.pmed.0030371","volume":"3","author":"MG Basanez","year":"2006","unstructured":"Basanez MG, Pion SD, Churcher TS, Breitling LP, Little MP, Boussinesq M (2006) River blindness: a success story under threat? PLoS Med 3:e371","journal-title":"PLoS Med"},{"key":"1133_CR4","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1007\/s002840010100","volume":"41","author":"C Bazzocchi","year":"2000","unstructured":"Bazzocchi C, Jamnongluk W, O\u2019Neill SL, Anderson TJ, Genchi C, Bandi C (2000) wsp gene sequences from the Wolbachia of filarial nematodes. Curr Microbiol 41:96\u2013100","journal-title":"Curr Microbiol"},{"key":"1133_CR5","first-page":"390","volume":"39","author":"DW B\u00fcttner","year":"1988","unstructured":"B\u00fcttner DW, Albiez EJ, von Essen J, Erichsen J (1988) Histological examination of adult Onchocerca volvulus and comparison with the collagenase technique. Trop Med Parasitol 39:390\u2013417","journal-title":"Trop Med Parasitol"},{"key":"1133_CR6","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.vetpar.2005.02.002","volume":"129","author":"GC Coles","year":"2005","unstructured":"Coles GC, Rhodes AC, Wolstenholme AJ (2005) Rapid selection for ivermectin resistance in Haemonchus contortus. Vet Parasitol 129:345\u2013347","journal-title":"Vet Parasitol"},{"key":"1133_CR7","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1016\/S0140-6736(00)02095-X","volume":"355","author":"A Hoerauf","year":"2000","unstructured":"Hoerauf A, Volkmann L, Hamelmann C, Adjei O, Autenrieth IB, Fleischer B, B\u00fcttner DW (2000) Endosymbiotic bacteria in worms as targets for a novel chemotherapy in filariasis. Lancet 355:1242\u20131243","journal-title":"Lancet"},{"key":"1133_CR8","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1016\/S0140-6736(00)04581-5","volume":"357","author":"A Hoerauf","year":"2001","unstructured":"Hoerauf A, Mand S, Adjei O, Fleischer B, B\u00fcttner DW (2001) Depletion of Wolbachia endobacteria in Onchocerca volvulus by doxycycline and microfilaridermia after ivermectin treatment. Lancet 357:1415\u20131416","journal-title":"Lancet"},{"key":"1133_CR9","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S1286-4579(03)00026-1","volume":"5","author":"A Hoerauf","year":"2003","unstructured":"Hoerauf A, Mand S, Volkmann L, Buttner M, Marfo-Debrekyei Y, Taylor M, Adjei O, B\u00fcttner DW (2003) Doxycycline in the treatment of human onchocerciasis: kinetics of Wolbachia endobacteria reduction and of inhibition of embryogenesis in female Onchocerca worms. Microbes Infect 5:261\u2013273","journal-title":"Microbes Infect"},{"key":"1133_CR10","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s00430-007-0062-1","volume":"197","author":"A Hoerauf","year":"2007","unstructured":"Hoerauf A, Specht S, Buttner M, Pfarr K, Mand S, Fimmers R, Marfo-Debrekyei Y, Konadu P, Debrah AY, Bandi C, Brattig N, Albers A, Larbi J, Batsa L, Adjei O, Buttner DW (2007) Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study. Med Microbiol Immunol 197:295\u2013311","journal-title":"Med Microbiol Immunol"},{"key":"1133_CR11","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.exppara.2004.06.006","volume":"107","author":"A Jolodar","year":"2004","unstructured":"Jolodar A, Fischer P, Buttner DW, Miller DJ, Schmetz C, Brattig NW (2004) Onchocerca volvulus: expression and immunolocalization of a nematode cathepsin D-like lysosomal aspartic protease. Exp Parasitol 107:145\u2013156","journal-title":"Exp Parasitol"},{"key":"1133_CR12","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1007\/s00436-007-0514-y","volume":"101","author":"M Kose","year":"2007","unstructured":"Kose M, Kozan E, Sevimli FK, Eser M (2007) The resistance of nematode parasites in sheep against anthelmintic drugs widely used in Western Turkey. Parasitol Res 101:563\u2013567","journal-title":"Parasitol Res"},{"key":"1133_CR13","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/j.0269-283X.2004.00496.x","volume":"18","author":"K Kutin","year":"2004","unstructured":"Kutin K, Kruppa TF, Brenya R, Garms R (2004) Efficiency of Simulium sanctipauli as a vector of Onchocerca volvulus in the forest zone of Ghana. Med Vet Entomol 18:167\u2013173","journal-title":"Med Vet Entomol"},{"key":"1133_CR14","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1016\/S0140-6736(04)16151-5","volume":"363","author":"MP Little","year":"2004","unstructured":"Little MP, Breitling LP, Basanez MG, Alley ES, Boatin BA (2004) Association between microfilarial load and excess mortality in onchocerciasis: an epidemiological study. Lancet 363:1514\u20131521","journal-title":"Lancet"},{"key":"1133_CR15","doi-asserted-by":"crossref","first-page":"878","DOI":"10.4269\/ajtmh.2007.77.878","volume":"77","author":"FO Richards Jr","year":"2007","unstructured":"Richards FO Jr, Amann J, Arana B, Punkosdy G, Klein R, Blanco C, Lopez B, Mendoza C, Dominguez A, Guarner J, Maguire JH, Eberhard M (2007) No depletion of Wolbachia from Onchocerca volvulus after a short course of rifampin and\/or azithromycin. Am J Trop Med Hyg 77:878\u2013882","journal-title":"Am J Trop Med Hyg"},{"key":"1133_CR16","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.vetpar.2007.06.023","volume":"148","author":"RG Soutello","year":"2007","unstructured":"Soutello RG, Seno MC, Amarante AF (2007) Anthelmintic resistance in cattle nematodes in northwestern Sao Paulo State, Brazil. Vet Parasitol 148:360\u2013364","journal-title":"Vet Parasitol"},{"key":"1133_CR17","first-page":"250","volume":"69","author":"MJ Taylor","year":"2003","unstructured":"Taylor MJ, Makunde W, McGarry HF, Mand S, Hoerauf A (2003) Doxycycline treatment of Wuchereria bancrofti: a double-blind placebo-controlled trial. Am J Trop Med Hyg 69:250, (Suppl)","journal-title":"Am J Trop Med Hyg"},{"key":"1133_CR18","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1475-2883-5-4","volume":"5","author":"S Townson","year":"2006","unstructured":"Townson S, Tagboto S, McGarry HF, Egerton GL, Taylor MJ (2006) Onchocerca parasites and Wolbachia endosymbionts: evaluation of a spectrum of antibiotic types for activity against Onchocerca gutturosa in vitro. Filaria J 5:4","journal-title":"Filaria J"},{"key":"1133_CR19","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.vetpar.2007.09.004","volume":"150","author":"AM Zeveren Van","year":"2007","unstructured":"Van Zeveren AM, Casaert S, Alvinerie M, Geldhof P, Claerebout E, Vercruysse J (2007) Experimental selection for ivermectin resistance in Ostertagia ostertagi in cattle. Vet Parasitol 150:104\u2013110","journal-title":"Vet Parasitol"},{"key":"1133_CR20","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1080\/00480169.2001.36211","volume":"49","author":"M Vickers","year":"2001","unstructured":"Vickers M, Venning M, McKenna PB, Mariadass B (2001) Resistance to macrocyclic lactone anthelmintics by Haemonchus contortus and Ostertagia circumcincta in sheep in New Zealand. N Z Vet J 49:101\u2013105","journal-title":"N Z Vet J"},{"key":"1133_CR21","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1046\/j.1365-3156.2003.01040.x","volume":"8","author":"L Volkmann","year":"2003","unstructured":"Volkmann L, Fischer K, Taylor M, Hoerauf A (2003) Antibiotic therapy in murine filariasis (Litomosoides sigmodontis): comparative effects of doxycycline and rifampicin on Wolbachia and filarial viability. TM IH Trop Med Int Health 8:392\u2013401","journal-title":"TM IH Trop Med Int Health"},{"key":"1133_CR22","first-page":"1","volume":"852","author":"WHO","year":"1995","unstructured":"WHO (1995) Onchocerciasis and its control. WHO Tech Rep Ser 852:1\u2013103","journal-title":"WHO Tech Rep Ser"}],"container-title":["Parasitology Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-008-1133-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00436-008-1133-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-008-1133-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T18:55:46Z","timestamp":1559069746000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00436-008-1133-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8,5]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["1133"],"URL":"https:\/\/doi.org\/10.1007\/s00436-008-1133-y","relation":{},"ISSN":["0932-0113","1432-1955"],"issn-type":[{"value":"0932-0113","type":"print"},{"value":"1432-1955","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,8,5]]}}}