{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T01:54:51Z","timestamp":1791251691467,"version":"4.1.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2012,9,5]],"date-time":"2012-09-05T00:00:00Z","timestamp":1346803200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitol Res"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1007\/s00436-012-3085-5","type":"journal-article","created":{"date-parts":[[2012,9,4]],"date-time":"2012-09-04T00:59:39Z","timestamp":1346720379000},"page":"2311-2315","source":"Crossref","is-referenced-by-count":90,"title":["Genetic variability of Blastocystis sp. isolated from symptomatic and asymptomatic individuals in Iran"],"prefix":"10.1007","volume":"111","author":[{"given":"A.","family":"Moosavi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Haghighi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Nazemalhosseini","family":"Mojarad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Zayeri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Alebouyeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Khazan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Kazemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. R.","family":"Zali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,9,5]]},"reference":[{"key":"3085_CR1","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0166-6851(97)00046-7","volume":"87","author":"CG Clark","year":"1997","unstructured":"Clark CG (1997) Extensive genetic diversity in Blastocystis hominis. Mol Biochem Parasitol 87:79\u201383","journal-title":"Mol Biochem Parasitol"},{"key":"3085_CR2","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1099\/0022-1317-49-6-489","volume":"49","author":"CG Clark","year":"2000","unstructured":"Clark CG (2000) Cryptic genetic variation in parasitic protozoa. J Med Microbiol 49:489\u2013491","journal-title":"J Med Microbiol"},{"key":"3085_CR3","first-page":"53","volume":"1","author":"N Daryani","year":"2006","unstructured":"Daryani N, Barmaki GH, Ettehad M, Sharif MH, Dehghan A et al (2006) A cross-sectional study of Blastocystis hominis in primary school children, Northwest Iran. Inter J Trop Med 1:53\u201357","journal-title":"Inter J Trop Med"},{"key":"3085_CR4","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1007\/s00436-008-1031-3","volume":"103","author":"F Dogruman-Al","year":"2008","unstructured":"Dogruman-Al F, Dagci H, Yoshikawa H, Kurt \u00d6, Demirel M (2008) A possible link between subtype 2 and asymptomatic infections of Blastocystis hominis. Parasitol Res 103:685\u2013689","journal-title":"Parasitol Res"},{"key":"3085_CR5","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1007\/s00436-009-1485-y","volume":"105","author":"MV Dom\u00ednguez-M\u00e1rquez","year":"2009","unstructured":"Dom\u00ednguez-M\u00e1rquez MV, Guna R, Mu\u00f1oz C, G\u00f3mez-Mu\u00f1oz MT, Borr\u00e1s R (2009) High prevalence of subtype 4 among isolates of Blastocystis hominis from symptomatic of a health district of Valencia (Spain). Parasitol Res 105:949\u2013945","journal-title":"Parasitol Res"},{"key":"3085_CR6","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.trstmh.2008.11.004","volume":"103","author":"A Haghighi","year":"2008","unstructured":"Haghighi A, Khorashad AS, Nazemalhosseini Mojarad E, Kazemi B, Nejad MR, Rasti S (2009) Frequency of enteric protozoan parasites among patients with gastrointestinal complaints in medical centers of Zahedan, Iran. Trans R Soc Trop Med Hyg 103:452\u2013454","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"3085_CR7","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1007\/s00436-010-2097-2","volume":"108","author":"DM Hameed","year":"2011","unstructured":"Hameed DM, Hassanin OM, Zuel-Fakkar NM (2011) Association of Blastocystis hominis genetic subtypes with urticaria. Parasitol Res 108:553\u2013560","journal-title":"Parasitol Res"},{"key":"3085_CR8","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1007\/s00436-007-0833-z","volume":"102","author":"EM Hussein","year":"2008","unstructured":"Hussein EM, Hussein AM, Eida MM, Atwa MM (2008) Pathophysiological variability of different genotypes of human Blastocystis hominis Egyptian isolates in experimentally infected rats. Parasitol Res 102:853\u2013860","journal-title":"Parasitol Res"},{"key":"3085_CR9","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1007\/s00436-011-2626-7","volume":"110","author":"DE Jimenez-Gonzalez","year":"2012","unstructured":"Jimenez-Gonzalez DE, Martinez-Flores WA, Reyes-Gordillo J, Ramirez-Miranda ME, Arroyo-Escalante S, Romero-Valdovinos M et al (2012) Blastocystis infection is associated with irritable bowel syndrome in a Mexican patient population. Parasitol Res 110:1269\u20131275","journal-title":"Parasitol Res"},{"key":"3085_CR10","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s00436-008-1198-7","volume":"104","author":"MS Jones","year":"2009","unstructured":"Jones MS, Whipps CM, Ganac RD, Hudson NR, Boroom K (2009) Association of Blastocystis subtype 3 and 1 with patients from an Oregon community presenting with chronic gastrointestinal illness. Parasitol Res 104:341\u2013345","journal-title":"Parasitol Res"},{"key":"3085_CR11","doi-asserted-by":"crossref","first-page":"393","DOI":"10.4269\/ajtmh.2001.65.393","volume":"65","author":"Y Kaneda","year":"2001","unstructured":"Kaneda Y, Horiki N, Cheng XJ, Fujita Y, Maruyama M et al (2001) Ribodemes of Blastocystis hominis isolated in Japan. AmJTrop Med Hyg 65:393\u2013396","journal-title":"AmJTrop Med Hyg"},{"issue":"4","key":"3085_CR12","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1007\/s00436-011-2665-0","volume":"110","author":"IL Lee","year":"2012","unstructured":"Lee IL, Tan TC, Tan PC, Nanthiney DR, Biraj MK, Surendra KM, Suresh KG (2012) Predominance of Blastocystis sp. subtype 4 in rural communities, Nepal. Parasitol Res 110(4):1553\u20131562","journal-title":"Parasitol Res"},{"key":"3085_CR13","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.parint.2007.06.001","volume":"56","author":"LH Li","year":"2007","unstructured":"Li LH, Zhou XN, Du ZW, Wang XZ, Wang LB, Jiang JY, Yoshikawa H, Steinmann P, Utzinger J, Wu Z, Chen JX, Chen SH, Zhang L (2007) Molecular epidemiology of human Blastocystis in a village in Yunnan Province, China. Parasitol Int 56:281\u2013286","journal-title":"Parasitol Int"},{"key":"3085_CR14","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1007\/s00436-011-2294-7","volume":"109","author":"D Meloni","year":"2011","unstructured":"Meloni D, Sanciu G, Poirier P, Alaoui H, El CM, Delhaes L et al (2011) Molecular subtyping of Blastocystis sp. isolates from symptomatic patients in Italy. Parasitol Res 109:613\u2013619","journal-title":"Parasitol Res"},{"key":"3085_CR15","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1179\/136485908X252197","volume":"102","author":"H Motazedian","year":"2008","unstructured":"Motazedian H, Ghasemi H, Sadjjadi SM (2008) Genomic diversity of Blastocystis hominis from patients in southern Iran. Ann Trop Med Parasitol 102:85\u201388","journal-title":"Ann Trop Med Parasitol"},{"key":"3085_CR16","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/j.ijpara.2011.06.010","volume":"41","author":"J Petra\u0161ova","year":"2011","unstructured":"Petra\u0161ova J, Uzlikova M, Kostka M, Petrz\u02c7elkova KJ, Huffman MA, Modry D (2011) Diversity and host specificity of Blastocystis in syntopic primates on Rubondo Island, Tanzania. Int J Parasitol 41:1113\u20131120","journal-title":"Int J Parasitol"},{"key":"3085_CR17","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1007\/s00436-005-1461-0","volume":"97","author":"MK Puthia","year":"2005","unstructured":"Puthia MK, Vaithilingam A, Lu J, Tan KS (2005) Degradation of human secretory immunoglobulin A by Blastocystis. Parasitol Res 97:386\u2013389","journal-title":"Parasitol Res"},{"key":"3085_CR18","doi-asserted-by":"crossref","first-page":"4114","DOI":"10.1128\/IAI.00328-06","volume":"74","author":"MK Puthia","year":"2006","unstructured":"Puthia MK, Sio SW, Lu J, Tan KS (2006) Blastocystis ratti induces contact-independent apoptosis, F-actin rearrangement, and barrier function disruption in IEC-6 cells. Infect Immun 74:4114\u20134223","journal-title":"Infect Immun"},{"key":"3085_CR19","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1128\/EC.00371-07","volume":"7","author":"MK Puthia","year":"2008","unstructured":"Puthia MK, Lu J, Tan KS (2008) Blastocystis ratti contains cysteine proteases that mediate interleukin-8 response from human intestinal epithelial cells in an NF-kappa B-dependent manner. Eukaryot Cell 7:435\u2013443","journal-title":"Eukaryot Cell"},{"issue":"1","key":"3085_CR20","first-page":"101","volume":"7","author":"M Rostami Nejad","year":"2010","unstructured":"Rostami Nejad M, Nazemalhosseini Mojarad E, Dabiri H, Nochi Z, Pourhoseingholi MA, Sahebekhtiari N et al (2010) A case\u2013control study of Blastocystis hominis among Iranian population. East Afr J Public Health 7(1):101\u2013104","journal-title":"East Afr J Public Health"},{"key":"3085_CR21","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s00436-009-1398-9","volume":"105","author":"L Souppart","year":"2009","unstructured":"Souppart L, Sanciu G, Cian A, Wawrzyniak I, Delbac F et al (2009) Molecular epidemiology of human Blastocystis isolates in France. Parasitol Res 105:413\u2013421","journal-title":"Parasitol Res"},{"key":"3085_CR22","doi-asserted-by":"crossref","unstructured":"Stensvold CR, Christiansen DB, Olsen KEP, Nielsen HV (2011) Blastocystis sp. Subtype 4 is common in Danish Blastocystis-positive patients presenting with acute diarrhea. Am J Trop Med Hyg 84(6):883\u2013885","DOI":"10.4269\/ajtmh.2011.11-0005"},{"key":"3085_CR23","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1128\/CMR.00022-08","volume":"21","author":"KSW Tan","year":"2008","unstructured":"Tan KSW (2008) New insights on classification, identification, and clinical relevance of Blastocystis spp. Clin Microbiol Rev 21:639\u2013665","journal-title":"Clin Microbiol Rev"},{"key":"3085_CR24","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1007\/s00436-009-1551-5","volume":"102","author":"TC Tan","year":"2009","unstructured":"Tan TC, Ong SC, Suresh KG (2009) Genetic variability of Blastocystis sp. isolates obtained from cancer and HIV\/AIDS patients. Parasitol Res 102:1283\u20131286","journal-title":"Parasitol Res"},{"key":"3085_CR25","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.parint.2010.03.009","volume":"59","author":"C Vogelberg","year":"2010","unstructured":"Vogelberg C, Stensvold CR, Monecke S, Ditzen A, Stopsack K, Heinrich-Grafe U, Pohlmann C (2010) Blastocystis sp. subtype 2 detection during recurrence of gastrointestinal and urticarial symptoms. Parasitol Int 59:469\u2013471","journal-title":"Parasitol Int"},{"key":"3085_CR26","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/s00436-007-0808-0","volume":"102","author":"KHS Wong","year":"2008","unstructured":"Wong KHS, Ng GC, Lin RTP, Yoshikawa H, Taylor MB et al (2008) Predominance of subtype 3 among Blastocystis isolates from a major hospital in Singapore. Parasitol Res 102:663\u2013670","journal-title":"Parasitol Res"},{"key":"3085_CR27","doi-asserted-by":"crossref","first-page":"383","DOI":"10.4269\/ajtmh.2004.70.383","volume":"70","author":"J Yakoob","year":"2004","unstructured":"Yakoob J, Jafri W, Jafri N, Khan R, Islam M et al (2004) Irritable bowel syndrome: in search of an etiology: role of Blastocystis hominis. AmJTrop Med Hyg 70:383\u2013385","journal-title":"AmJTrop Med Hyg"},{"key":"3085_CR28","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1007\/s00436-010-1761-x","volume":"106","author":"J Yakoob","year":"2010","unstructured":"Yakoob J, Jafri W, Beg MA, Abbas Z, Naz S et al (2010) Irritable bowel syndrome: is it associated with genotypes of Blastocystis hominis. Parasitol Res 106:1033\u20131038","journal-title":"Parasitol Res"},{"key":"3085_CR29","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1007\/s00436-006-0186-z","volume":"99","author":"Y Yan","year":"2006","unstructured":"Yan Y, Su S, Lai R, Liao H, Ye J et al (2006) Genetic variability of Blastocystis hominis isolates in China. Parasitol Res 99:597\u2013601","journal-title":"Parasitol Res"},{"key":"3085_CR30","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1007\/s00436-007-0672-y","volume":"101","author":"Y Yan","year":"2007","unstructured":"Yan Y, Su S, Ye J, Lai X, Lai R (2007) Blastocystis sp. subtype 5: a possibly zoonotic genotype. Parasitol Res 101:1527\u20131532","journal-title":"Parasitol Res"},{"key":"3085_CR31","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s00436-004-1230-5","volume":"94","author":"H Yoshikawa","year":"2004","unstructured":"Yoshikawa H, Wu Z, Kimata I, Iseki M, Ali IKMD et al (2004) Polymerase chain reaction-based genotype classification among human Blastocystis hominis populations isolated from different countries. Parasitol Res 94:22\u201329","journal-title":"Parasitol Res"},{"key":"3085_CR32","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.vetpar.2008.11.029","volume":"160","author":"H Yoshikawa","year":"2009","unstructured":"Yoshikawa H, Wu Z, Pandey K, Pandey BD, Sherchnad JB et al (2009) Molecular characterization of Blastocystis isolates from children and rhesus monkeys in Kathmandu, Nepal. Vet Parasitol 160:295\u2013300","journal-title":"Vet Parasitol"},{"key":"3085_CR33","doi-asserted-by":"crossref","first-page":"268","DOI":"10.7883\/yoken.JJID.2004.268","volume":"57","author":"MR Zali","year":"2004","unstructured":"Zali MR, Mehr AJ, Rezaian M, Meamar AR, Vaziri S, Mohraz M (2004) Prevalence of intestinal parasitic pathogens among HIV positive individuals in Iran. Jpn J Infect Dis 57:268\u2013270","journal-title":"Jpn J Infect Dis"},{"issue":"6","key":"3085_CR34","first-page":"743","volume":"35","author":"X Zhang","year":"2006","unstructured":"Zhang X, Qiao JY, Da R, Li YQ, Yao FR (2006) Vitro culture of Blastocystis hominis in medium DMEM. Wei Sheng Yan Jiu 35(6):743\u2013746","journal-title":"Wei Sheng Yan Jiu"}],"container-title":["Parasitology Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-012-3085-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00436-012-3085-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-012-3085-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,28]],"date-time":"2024-04-28T18:23:05Z","timestamp":1714328585000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00436-012-3085-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,5]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["3085"],"URL":"https:\/\/doi.org\/10.1007\/s00436-012-3085-5","relation":{},"ISSN":["0932-0113","1432-1955"],"issn-type":[{"value":"0932-0113","type":"print"},{"value":"1432-1955","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,5]]}}}