{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T13:55:39Z","timestamp":1788875739864,"version":"build-2803163510"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2012,9,23]],"date-time":"2012-09-23T00:00:00Z","timestamp":1348358400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitol Res"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1007\/s00436-012-3125-1","type":"journal-article","created":{"date-parts":[[2012,9,22]],"date-time":"2012-09-22T02:38:58Z","timestamp":1348281538000},"page":"193-198","source":"Crossref","is-referenced-by-count":35,"title":["In vitro and in vivo treatments of Echinococcus granulosus with Huaier aqueous extract and albendazole liposome"],"prefix":"10.1007","volume":"112","author":[{"given":"Hailong","family":"Lv","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufeng","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongli","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shijie","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,9,23]]},"reference":[{"key":"3125_CR1","first-page":"144","volume":"25","author":"SA Abu-Eshy","year":"2006","unstructured":"Abu-Eshy SA (2006) Clinical characteristics, diagnosis and surgical management of hydatid cysts. West Afr J Med 25:144\u2013152","journal-title":"West Afr J Med"},{"key":"3125_CR2","doi-asserted-by":"crossref","first-page":"123","DOI":"10.2165\/00128072-200103020-00005","volume":"3","author":"D Anadol","year":"2001","unstructured":"Anadol D, Ozcelik U, Kiper N, Gocmen A (2001) Treatment of hydatid disease. Paediatr Drugs 3:123\u2013135","journal-title":"Paediatr Drugs"},{"key":"3125_CR3","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0020-7519(95)00095-X","volume":"26","author":"N Casado","year":"1996","unstructured":"Casado N, Perez-Serrano J, Denegri G, Rodriguez-Caabeiro F (1996) Development of chemotherapeutic model for the in vitro screening of drugs against Echinoccus granulosus cysts: the effects of an albendazole\u2013albendazole sulphoxide combination. Int J Parasitol 26:59\u201365","journal-title":"Int J Parasitol"},{"key":"3125_CR4","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1007\/s00268-009-9982-9","volume":"33","author":"C Dziri","year":"2009","unstructured":"Dziri C, Haouet K, Fingerhut A, Zaouche A (2009) Management of cystic echinococcosis complications and dissemination: where is the evidence? World J Surg 33:1266\u20131273","journal-title":"World J Surg"},{"key":"3125_CR5","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1128\/CMR.17.1.107-135.2004","volume":"17","author":"J Eckert","year":"2004","unstructured":"Eckert J, Deplazes P (2004) Biological, epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern. Clin Microbiol Rev 17:107\u2013135","journal-title":"Clin Microbiol Rev"},{"key":"3125_CR6","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0001-706X(02)00217-6","volume":"85","author":"J El-On","year":"2003","unstructured":"El-On J (2003) Benzimidazole treatment of cystic echinococcosis. Acta Trop 85:243\u2013252","journal-title":"Acta Trop"},{"key":"3125_CR7","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1097\/MAJ.0b013e31814252f8","volume":"334","author":"ME Falagas","year":"2007","unstructured":"Falagas ME, Bliziotis IA (2007) Albendazole for the treatment of human echinococcosis: a review of comparative clinical trials. Am J Med Sci 334:171\u2013179","journal-title":"Am J Med Sci"},{"key":"3125_CR8","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1017\/S0031182007003198","volume":"134","author":"A Hemphill","year":"2007","unstructured":"Hemphill A, Spicher M, Stadelmann B, Mueller J, Naguleswaran A, Gottstein B, Walker M (2007) Innovative chemotherapeutical treatment options for alveolar and cystic echinococcosis. Parasitology 134:1657\u20131670","journal-title":"Parasitology"},{"key":"3125_CR9","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.vetpar.2004.12.017","volume":"129","author":"A Horiuchi","year":"2005","unstructured":"Horiuchi A, Satou T, Akao N, Koike K, Fujita K, Nikaido T (2005) The effect of free and polyethylene glycol-liposome-entrapped albendazole on larval mobility and number in Toxocara canis infected mice. Vet Parasitol 129:83\u201387","journal-title":"Vet Parasitol"},{"key":"3125_CR10","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1128\/AAC.43.5.1052","volume":"43","author":"K Ingold","year":"1999","unstructured":"Ingold K, Bigler P, Thormann W, Cavaliero T, Gottstein B, Hemphill A (1999) Efficacies of albendazole sulfoxide and albendazole sulfone against in vitro-cultivated Echinococcus multilocularis metacestodes. Antimicrob Agents Chemother 43:1052\u20131061","journal-title":"Antimicrob Agents Chemother"},{"key":"3125_CR11","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/j.jep.2011.08.065","volume":"141","author":"LF Liu","year":"2012","unstructured":"Liu LF, Durairajan SS, Lu JH, Koo I, Li M (2012) In vitro screening on amyloid precursor protein modulation of plants used in Ayurvedic and Traditional Chinese medicine for memory improvement. J Ethnopharmacol 141:754\u2013760","journal-title":"J Ethnopharmacol"},{"key":"3125_CR12","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1007\/s00268-005-7691-6","volume":"29","author":"C Manterola","year":"2005","unstructured":"Manterola C, Mansilla JA, Fonseca F (2005) Preoperative albendazole and scolices viability in patients with hepatic echinococcosis. World J Surg 29:750\u2013753","journal-title":"World J Surg"},{"key":"3125_CR13","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0020-7519(94)90029-9","volume":"24","author":"J Perez-Serrano","year":"1994","unstructured":"Perez-Serrano J, Casado N, Guillermo D, Rodriguez-Caabeiro F (1994) The effects of albendazole and albendazole sulphoxide combination-therapy on Echinococcus granulosus in vitro. Int J Parasitol 24:219\u2013224","journal-title":"Int J Parasitol"},{"key":"3125_CR14","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/j.1440-1746.2004.03535.x","volume":"20","author":"C Polat","year":"2005","unstructured":"Polat C, Dervisoglu A, Hokelek M, Yetim I, Buyukkarabacak Y, Ozkutuk Y, Erzurumlu K (2005) Dual treatment of albendazole in hepatic hydatidosis: new therapeutic modality in 52 cases. J Gastroenterol Hepatol 20:421\u2013425","journal-title":"J Gastroenterol Hepatol"},{"key":"3125_CR15","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s00268-004-7587-x","volume":"29","author":"K Puryan","year":"2005","unstructured":"Puryan K, Karadayi K, Topcu O, Canbay E, Sumer Z, Turan M, Karayalcin K, Sen M (2005) Chlorhexidine gluconate: an ideal scolicidal agent in the treatment of intraperitoneal hydatidosis? World J Surg 29:227\u2013230","journal-title":"World J Surg"},{"key":"3125_CR16","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1007\/s11596-009-0212-3","volume":"29","author":"J Ren","year":"2009","unstructured":"Ren J, Zheng C, Feng G, Liang H, Xia X, Fang J, Duan X, Zhao H (2009) Inhibitory effect of extract of fungi of Huaier on hepatocellular carcinoma cells. J Huazhong Univ Sci Technol Med Sci 29:198\u2013201","journal-title":"J Huazhong Univ Sci Technol Med Sci"},{"key":"3125_CR17","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0065-308X(02)51005-8","volume":"51","author":"M Siles-Lucas","year":"2002","unstructured":"Siles-Lucas M, Hemphill A (2002) Cestode parasites: application of in vivo and in vitro models for studies on the host\u2013parasite relationship. Adv Parasitol 51:133\u2013230","journal-title":"Adv Parasitol"},{"key":"3125_CR18","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.ijpara.2004.01.006","volume":"34","author":"M Stettler","year":"2004","unstructured":"Stettler M, Rossignol JF, Fink R, Walker M, Gottstein B, Merli M, Theurillat R, Thormann W, Dricot E, Segers R, Hemphill A (2004) Secondary and primary murine alveolar echinococcosis: combined albendazole\/nitazoxanide chemotherapy exhibits profound anti-parasitic activity. Int J Parasitol 34:615\u2013624","journal-title":"Int J Parasitol"},{"key":"3125_CR19","first-page":"199","volume":"46","author":"U Thatte","year":"2000","unstructured":"Thatte U, Bagadey S, Dahanukar S (2000) Modulation of programmed cell death by medicinal plants. Cell Mol Biol (Noisy-le-Grand) 46:199\u2013214","journal-title":"Cell Mol Biol (Noisy-le-Grand)"},{"key":"3125_CR20","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/1755-8794-4-38","volume":"4","author":"E Wang","year":"2011","unstructured":"Wang E, Bussom S, Chen J, Quinn C, Bedognetti D, Lam W, Guan F, Jiang Z, Mark Y, Zhao Y, Stroncek DF, White J, Marincola FM, Cheng YC (2011) Interaction of a traditional Chinese Medicine (PHY906) and CPT-11 on the inflammatory process in the tumor microenvironment. BMC Med Genomics 4:38","journal-title":"BMC Med Genomics"},{"issue":"Pt 2","key":"3125_CR21","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1017\/S003118200006635X","volume":"113","author":"H Wen","year":"1996","unstructured":"Wen H, New RR, Muhmut M, Wang JH, Wang YH, Zhang JH, Shao YM, Craig PS (1996) Pharmacology and efficacy of liposome-entrapped albendazole in experimental secondary alveolar echinococcosis and effect of co-administration with cimetidine. Parasitology 113(Pt 2):111\u2013121","journal-title":"Parasitology"},{"key":"3125_CR22","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1111\/j.1349-7006.2010.01680.x","volume":"101","author":"N Zhang","year":"2010","unstructured":"Zhang N, Kong X, Yan S, Yuan C, Yang Q (2010) Huaier aqueous extract inhibits proliferation of breast cancer cells by inducing apoptosis. Cancer Sci 101:2375\u20132383","journal-title":"Cancer Sci"}],"container-title":["Parasitology Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-012-3125-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00436-012-3125-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-012-3125-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,4]],"date-time":"2019-07-04T00:16:44Z","timestamp":1562199404000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00436-012-3125-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,23]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["3125"],"URL":"https:\/\/doi.org\/10.1007\/s00436-012-3125-1","relation":{},"ISSN":["0932-0113","1432-1955"],"issn-type":[{"value":"0932-0113","type":"print"},{"value":"1432-1955","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,23]]}}}