{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,20]],"date-time":"2025-07-20T03:45:09Z","timestamp":1752983109853},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2014,1,23]],"date-time":"2014-01-23T00:00:00Z","timestamp":1390435200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitol Res"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1007\/s00436-014-3757-4","type":"journal-article","created":{"date-parts":[[2014,1,22]],"date-time":"2014-01-22T12:13:27Z","timestamp":1390392807000},"page":"1195-1200","source":"Crossref","is-referenced-by-count":14,"title":["Simultaneous priming with DNA encoding Sm-p80 and boosting with Sm-p80 protein confers protection against challenge infection with Schistosoma mansoni in mice"],"prefix":"10.1007","volume":"113","author":[{"given":"Loc","family":"Le","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weidong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Souvik","family":"Karmakar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gul","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Workineh","family":"Torben","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afzal A.","family":"Siddiqui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,1,23]]},"reference":[{"key":"3757_CR1","doi-asserted-by":"crossref","first-page":"2830","DOI":"10.1016\/j.vaccine.2009.02.096","volume":"27","author":"G Ahmad","year":"2009","unstructured":"Ahmad G, Zhang W, Torben W, Damian RT, Wolf RF, White GL, Chavez-Suarez M, Kennedy RC, Siddiqui AA (2009a) Protective and antifecundity effects of Sm-p80-based DNA vaccine formulation against Schistosoma mansoni in a nonhuman primate model. Vaccine 27:2830\u20132837","journal-title":"Vaccine"},{"key":"3757_CR2","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1007\/s00436-009-1646-z","volume":"105","author":"G Ahmad","year":"2009","unstructured":"Ahmad G, Zhang W, Torben W, Haskins C, Diggs S, Noor Z, Le L, Siddiqui AA (2009b) Prime-boost and recombinant protein vaccination strategies using Sm-p80 protects against Schistosoma mansoni infection in the mouse model to levels previously attainable only by the irradiated cercarial vaccine. Parasitol Res 105:1767\u20131777","journal-title":"Parasitol Res"},{"key":"3757_CR3","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1093\/infdis\/jir545","volume":"204","author":"G Ahmad","year":"2011","unstructured":"Ahmad G, Zhang W, Torben W, Ahrorov A, Damian RT, Wolf RF, White GL, Carey DW, Mwinzi PN, Ganley-Leal L, Kennedy RC, Siddiqui AA (2011) Preclinical prophylactic efficacy testing of Sm-p80-based vaccine in a nonhuman primate model of Schistosoma mansoni infection and immunoglobulin G and E responses to Sm-p80 in human serum samples from an area where schistosomiasis is endemic. J Infect Dis 204:1437\u20131449","journal-title":"J Infect Dis"},{"key":"3757_CR4","first-page":"60","volume":"76","author":"R Bergquist","year":"1990","unstructured":"Bergquist R (1990) Prospects of vaccination against schistosomiasis. Scand J Infect Dis Suppl 76:60\u201371","journal-title":"Scand J Infect Dis Suppl"},{"key":"3757_CR5","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0001-706X(02)00048-7","volume":"82","author":"R Bergquist","year":"2002","unstructured":"Bergquist R, Al-Sherbiny M, Barakat R, Olds R (2002) Blueprint for schistosomiasis vaccine development. Acta Trop 82:183\u2013192","journal-title":"Acta Trop"},{"key":"3757_CR6","doi-asserted-by":"crossref","first-page":"e244","DOI":"10.1371\/journal.pntd.0000244","volume":"2","author":"R Bergquist","year":"2008","unstructured":"Bergquist R, Utzinger J, McManus DP (2008) Trick or treat: the role of vaccines in integrated schistosomiasis control. PLoS Negl Trop Dis 2:e244","journal-title":"PLoS Negl Trop Dis"},{"key":"3757_CR7","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1111\/j.1365-3024.2003.00651.x","volume":"25","author":"AA 'Dara","year":"2003","unstructured":"'Dara AA, Skelly PJ, Walker CM, Harn DA (2003) A DNA-prime\/protein-boost vaccination regimen enhances Th2 immune responses but not protection following Schistosoma mansoni infection. Parasite Immunol 25:429\u2013437","journal-title":"Parasite Immunol"},{"key":"3757_CR8","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/S0169-4758(98)01316-7","volume":"14","author":"R Ridi El","year":"1998","unstructured":"El Ridi R (1998) More on the search for a schistosomiasis vaccine. Parasitol Today 14:436","journal-title":"Parasitol Today"},{"key":"3757_CR9","doi-asserted-by":"crossref","first-page":"e78639","DOI":"10.1371\/journal.pone.0078639","volume":"8","author":"AP Junqueira-Kipnis","year":"2013","unstructured":"Junqueira-Kipnis AP, de Oliveira FM, Trentini MM, Tiwari S, Chen B, Resende DP, Silva BD, Chen M, Tesfa L, Jacobs WR Jr, Kipnis A (2013) Prime-boost with Mycobacterium smegmatis recombinant vaccine improves protection in mice infected with Mycobacterium tuberculosis. PLoS One 8:e78639","journal-title":"PLoS One"},{"key":"3757_CR10","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.coi.2009.05.016","volume":"21","author":"S Lu","year":"2009","unstructured":"Lu S (2009) Heterologous prime-boost vaccination. Curr Opin Immunol 21:346\u2013351","journal-title":"Curr Opin Immunol"},{"key":"3757_CR11","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.cellimm.2013.10.001","volume":"285","author":"M Lu","year":"2013","unstructured":"Lu M, Xia ZY, Bao L (2013) Enhancement of antimycobacterial Th1-cell responses by a Mycobacterium bovis BCG prime-protein boost vaccination strategy. Cell Immunol 285:111\u2013117","journal-title":"Cell Immunol"},{"key":"3757_CR12","doi-asserted-by":"crossref","first-page":"e1582","DOI":"10.1371\/journal.pntd.0001582","volume":"6","author":"S Lustigman","year":"2012","unstructured":"Lustigman S, Prichard RK, Gazzinelli A, Grant WN, Boatin BA, McCarthy JS, Basanez MG (2012) A research agenda for helminth diseases of humans: the problem of helminthiases. PLoS Negl Trop Dis 6:e1582","journal-title":"PLoS Negl Trop Dis"},{"key":"3757_CR13","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1128\/CMR.00046-07","volume":"21","author":"DP McManus","year":"2008","unstructured":"McManus DP, Loukas A (2008) Current status of vaccines for schistosomiasis. Clin Microbiol Rev 21:225\u2013242","journal-title":"Clin Microbiol Rev"},{"key":"3757_CR14","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/S0169-4758(99)01569-0","volume":"15","author":"M Nyindo","year":"1999","unstructured":"Nyindo M, Farah IO (1999) The baboon as a non-human primate model of human schistosome infection. Parasitol Today 15:478\u2013482","journal-title":"Parasitol Today"},{"key":"3757_CR15","doi-asserted-by":"crossref","first-page":"e1549","DOI":"10.1371\/journal.pntd.0001549","volume":"6","author":"RK Prichard","year":"2012","unstructured":"Prichard RK, Basanez MG, Boatin BA, McCarthy JS, Garcia HH, Yang GJ, Sripa B, Lustigman S (2012) A research agenda for helminth diseases of humans: intervention for control and elimination. PLoS Negl Trop Dis 6:e1549","journal-title":"PLoS Negl Trop Dis"},{"key":"3757_CR16","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1586\/erv.09.14","volume":"8","author":"K Radosevic","year":"2009","unstructured":"Radosevic K, Rodriguez A, Lemckert A, Goudsmit J (2009) Heterologous prime-boost vaccinations for poverty-related diseases: advantages and future prospects. Expert Rev Vaccines 8:577\u2013592","journal-title":"Expert Rev Vaccines"},{"key":"3757_CR17","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.actatropica.2012.04.013","volume":"128","author":"D Rollinson","year":"2013","unstructured":"Rollinson D, Knopp S, Levitz S, Stothard JR, Tchuem Tchuente LA, Garba A, Mohammed KA, Schur N, Person B, Colley DG, Utzinger J (2013) Time to set the agenda for schistosomiasis elimination. Acta Trop 128:423\u2013440","journal-title":"Acta Trop"},{"key":"3757_CR18","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0925-4439(93)90087-H","volume":"1181","author":"AA Siddiqui","year":"1993","unstructured":"Siddiqui AA, Zhou Y, Podesta RB, Karcz SR, Tognon CE, Strejan GH, Dekaban GA, Clarke MW (1993) Characterization of Ca(2+)-dependent neutral protease (calpain) from human blood flukes, Schistosoma mansoni. Biochim Biophys Acta 1181:37\u201344","journal-title":"Biochim Biophys Acta"},{"key":"3757_CR19","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1007\/s00436-008-0887-6","volume":"102","author":"AA Siddiqui","year":"2008","unstructured":"Siddiqui AA, Ahmad G, Damian RT, Kennedy RC (2008) Experimental vaccines in animal models for schistosomiasis. Parasitol Res 102:825\u2013833","journal-title":"Parasitol Res"},{"key":"3757_CR20","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.4161\/hv.7.11.17017","volume":"7","author":"AA Siddiqui","year":"2011","unstructured":"Siddiqui AA, Siddiqui BA, Ganley-Leal L (2011) Schistosomiasis vaccines. Hum Vaccin 7:1192\u20131197","journal-title":"Hum Vaccin"},{"key":"3757_CR21","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.cyto.2009.07.581","volume":"48","author":"H Tallima","year":"2009","unstructured":"Tallima H, Salah M, Guirguis FR, El RR (2009) Transforming growth factor-beta and Th17 responses in resistance to primary murine schistosomiasis mansoni. Cytokine 48:239\u2013245","journal-title":"Cytokine"},{"key":"3757_CR22","doi-asserted-by":"crossref","first-page":"e2106","DOI":"10.1371\/journal.pntd.0002106","volume":"7","author":"CC Terer","year":"2013","unstructured":"Terer CC, Bustinduy AL, Magtanong RV, Muhoho N, Mungai PL, Muchiri EM, Kitron U, King CH, Mutuku FM (2013) Evaluation of the health-related quality of life of children in schistosoma haematobium-endemic communities in Kenya: a cross-sectional study. PLoS Negl Trop Dis 7:e2106","journal-title":"PLoS Negl Trop Dis"},{"key":"3757_CR23","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1038\/sj.icb.7100014","volume":"85","author":"MS Wilson","year":"2007","unstructured":"Wilson MS, Mentink-Kane MM, Pesce JT, Ramalingam TR, Thompson R, Wynn TA (2007) Immunopathology of schistosomiasis. Immunol Cell Biol 85:148\u2013154","journal-title":"Immunol Cell Biol"},{"key":"3757_CR24","doi-asserted-by":"crossref","first-page":"802","DOI":"10.2307\/3281488","volume":"72","author":"BW Young","year":"1986","unstructured":"Young BW, Podesta RB (1986) Complement and 5-HT increase phosphatidylcholine incorporation into the outer bilayers of Schistosoma mansoni. J Parasitol 72:802\u2013803","journal-title":"J Parasitol"},{"key":"3757_CR25","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1086\/651147","volume":"201","author":"W Zhang","year":"2010","unstructured":"Zhang W, Ahmad G, Torben W, Noor Z, Le L, Damian RT, Wolf RF, White GL, Chavez-Suarez M, Podesta RB, Kennedy RC, Siddiqui AA (2010a) Sm-p80-based DNA vaccine provides baboons with levels of protection against Schistosoma mansoni infection comparable to those achieved by the irradiated cercarial vaccine. J Infect Dis 201:1105\u20131112","journal-title":"J Infect Dis"},{"key":"3757_CR26","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1111\/j.1365-3024.2009.01181.x","volume":"32","author":"W Zhang","year":"2010","unstructured":"Zhang W, Ahmad G, Torben W, Siddiqui AA (2010b) Sm-p80-based DNA vaccine made in a human use approved vector VR1020 protects against challenge infection with Schistosoma mansoni in mouse. Parasite Immunol 32:252\u2013258","journal-title":"Parasite Immunol"},{"key":"3757_CR27","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.actatropica.2011.01.010","volume":"118","author":"W Zhang","year":"2011","unstructured":"Zhang W, Ahmad G, Torben W, Siddiqui AA (2011) Schistosoma mansoni antigen Sm-p80: prophylactic efficacy of a vaccine formulated in human approved plasmid vector and adjuvant (VR 1020 and alum). Acta Trop 118:142\u2013151","journal-title":"Acta Trop"},{"key":"3757_CR28","doi-asserted-by":"crossref","first-page":"333","DOI":"10.2307\/3282583","volume":"75","author":"Y Zhou","year":"1989","unstructured":"Zhou Y, Podesta RB (1989) Effects of serotonin (5HT) and complement C3 on the synthesis of the surface membrane precursors of adult Schistosoma mansoni. J Parasitol 75:333\u2013343","journal-title":"J Parasitol"}],"container-title":["Parasitology Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-014-3757-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00436-014-3757-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-014-3757-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T23:04:46Z","timestamp":1559084686000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00436-014-3757-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,23]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["3757"],"URL":"https:\/\/doi.org\/10.1007\/s00436-014-3757-4","relation":{},"ISSN":["0932-0113","1432-1955"],"issn-type":[{"value":"0932-0113","type":"print"},{"value":"1432-1955","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,23]]}}}