{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T05:55:12Z","timestamp":1771048512486,"version":"3.50.1"},"reference-count":56,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2015,2,17]],"date-time":"2015-02-17T00:00:00Z","timestamp":1424131200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Parasitol Res"],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1007\/s00436-015-4347-9","type":"journal-article","created":{"date-parts":[[2015,2,17]],"date-time":"2015-02-17T09:54:38Z","timestamp":1424166878000},"page":"1661-1670","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Inducible nitric oxide synthase response and associated cytokine gene expression in the spleen of mice infected with Clonorchis sinensis"],"prefix":"10.1007","volume":"114","author":[{"given":"Ji-Qing","family":"Shen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing-Li","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Xue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Bing","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi-Hua","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Chao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying-Dan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Nong","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,2,17]]},"reference":[{"key":"4347_CR1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1002\/jlb.58.1.23","volume":"58","author":"BC Ahvazi","year":"1995","unstructured":"Ahvazi BC, Jacobs P, Stevenson MM (1995) Role of macrophage-derived nitric oxide in suppression of lymphocyte proliferation during blood-stage malaria. J Leukoc Biol 58:23\u201331","journal-title":"J Leukoc Biol"},{"key":"4347_CR2","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1089\/jir.2007.0003","volume":"27","author":"M Amri","year":"2007","unstructured":"Amri M, Aissa SA, Belguendouz H, Mezioug D, Touil-Boukoffa C (2007) In vitro antihydatic action of IFN-gamma is dependent on the nitric oxide pathway. J Interferon Cytokine Res 27:781\u2013787","journal-title":"J Interferon Cytokine Res"},{"key":"4347_CR3","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1182\/blood.V95.1.212","volume":"95","author":"I Angulo","year":"2000","unstructured":"Angulo I, de las Heras FG, Garc\u00eda-Bustos JF, Gargallo D, Mu\u00f1oz-Fern\u00e1ndez MA, Fresno M (2000) Nitric oxide-producing CD11b(+)Ly-6G(Gr-1)(+)CD31(ER-MP12)(+) cells in the spleen of cyclophosphamide-treated mice: implications for T-cell responses in immunosuppressed mice. Blood 95:212\u2013220","journal-title":"Blood"},{"key":"4347_CR4","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/j.immuni.2013.10.010","volume":"39","author":"V Bronte","year":"2013","unstructured":"Bronte V, Pittet MJ (2013) The spleen in local and systemic regulation of immunity. Immunity 39:806\u2013818","journal-title":"Immunity"},{"key":"4347_CR5","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s00436-003-0934-2","volume":"91","author":"YK Choi","year":"2003","unstructured":"Choi YK, Yoon BI, Won YS, Lee CH, Hyun BH, Kim HC, Oh GT, Kim DY (2003) Cytokine responses in mice infected with Clonorchis sinensis. Parasitol Res 91:87\u201393","journal-title":"Parasitol Res"},{"key":"4347_CR6","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1046\/j.1365-2567.1999.00723.x","volume":"97","author":"WJ Dai","year":"1999","unstructured":"Dai WJ, Gottstein B (1999) Nitric oxide-mediated immunosuppression following murine Echinococcus multilocularis infection. Immunology 97:107\u2013116","journal-title":"Immunology"},{"key":"4347_CR7","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1046\/j.1365-2567.2003.01567.x","volume":"108","author":"WJ Dai","year":"2003","unstructured":"Dai WJ, Waldvogel A, Jungi T, Stettler M, Gottstein B (2003) Inducible nitric oxide synthase deficiency in mice increases resistance to chronic infection with Echinococcus multilocularis. Immunology 108:238\u2013244","journal-title":"Immunology"},{"key":"4347_CR8","doi-asserted-by":"crossref","first-page":"4020","DOI":"10.4049\/jimmunol.166.6.4020","volume":"166","author":"L Das","year":"2001","unstructured":"Das L, Datta N, Bandyopadhyay S, Das PK (2001) Successful therapy of lethal murine visceral leishmaniasis with cystatin involves up-regulation of nitric oxide and a favorable T cell response. J Immunol 166:4020\u20134028","journal-title":"J Immunol"},{"key":"4347_CR9","first-page":"S1","volume":"20","author":"CA Dinarello","year":"2002","unstructured":"Dinarello CA (2002) The IL-1 family and inflammatory diseases. Clin Exp Rheumatol 20:S1\u2013S13","journal-title":"Clin Exp Rheumatol"},{"key":"4347_CR10","first-page":"289","volume":"4","author":"CA Dinarello","year":"2013","unstructured":"Dinarello CA, Novick D, Kim S, Kaplanski G (2013) Interleukin- 18 and IL-18 binding protein. Front Immunol 4:289. doi: 10.3389\/fimmu.2013.00289","journal-title":"Front Immunol"},{"key":"4347_CR11","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1007\/s00436-010-2183-5","volume":"108","author":"FR Santos dos","year":"2011","unstructured":"dos Santos FR, Vieira PM, Correa-Oliveira R, Giunchetti RC, Carneiro CM, Reis AB, Malaquias LC (2011) Qualitative and quantitative immunohistochemical evaluation of iNOS expression in the spleen of dogs naturally infected with Leishmania chagasi. Parasitol Res 108:1397\u20131403","journal-title":"Parasitol Res"},{"key":"4347_CR12","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1007\/s00262-011-0998-2","volume":"60","author":"NK Egilmez","year":"2011","unstructured":"Egilmez NK, Harden JL, Virtuoso LP, Schwendener RA, Kilinc MO (2011) Nitric oxide short-circuits interleukin-12-mediated tumor regression. Cancer Immunol Immunother 60:839\u2013845","journal-title":"Cancer Immunol Immunother"},{"key":"4347_CR13","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1046\/j.1365-3024.2002.00598.x","volume":"24","author":"EY Espinoza","year":"2002","unstructured":"Espinoza EY, P\u00e9rez-Arellano JL, Carranza C, Coll\u00eda F, Muro A (2002) In vivo inhibition of inducible nitric oxide synthase decreases lung injury induced by Toxocara canis in experimentally infected rats. Parasite Immunol 24:511\u2013520","journal-title":"Parasite Immunol"},{"key":"4347_CR14","first-page":"46","volume":"3","author":"L Fu","year":"2008","unstructured":"Fu L, Li Y, Liu Y, Tang R, Du W, Zheng K, Xiao Y, Guo Q, Dai Q (2008) Establishment and comparison on mice model of Clonorchis sinensis. Journal of Pathogen Biology (in Chinese) 3:46\u201348","journal-title":"Journal of Pathogen Biology (in Chinese)"},{"key":"4347_CR15","doi-asserted-by":"crossref","first-page":"3491","DOI":"10.1073\/pnas.90.8.3491","volume":"90","author":"DA Geller","year":"1993","unstructured":"Geller DA, Lowenstein CJ, Shapiro RA, Nussler AK, Di Silvio M, Wang SC, Nakayama DK, Simmons RL, Snyder SH, Billiar TR (1993) Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes. Proc Natl Acad Sci U S A 90:3491\u20133495","journal-title":"Proc Natl Acad Sci U S A"},{"key":"4347_CR16","first-page":"1827","volume":"29","author":"HC Gerard","year":"2002","unstructured":"Gerard HC, Wang Z, Whittum-Hudson JA, El-Gabalawy H, Goldbach-Mansky R, Bardin T, Schumacher HR, Hudson AP (2002) Cytokine and chemokine mRNA produced in synovial tissue chronically-infected with Chlamydia trachomatis and C. pneumoniae. J Rheumatol 29:1827\u20131835","journal-title":"J Rheumatol"},{"key":"4347_CR17","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0165-2478(94)00158-8","volume":"43","author":"SJ Green","year":"1994","unstructured":"Green SJ, Scheller LF, Marletta MA, Seguin MC, Klotz FW, Slayter M, Nelson BJ, Nacy CA (1994) Nitric oxide: cytokine-regulation of nitric oxide in host resistance to intracellular pathogens. Immunol Lett 43:87\u201394","journal-title":"Immunol Lett"},{"key":"4347_CR18","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.parint.2011.06.007","volume":"61","author":"S-T Hong","year":"2012","unstructured":"Hong S-T, Fang Y (2012) Clonorchis sinensis and clonorchiasis, an update. Parasitol Int 61:17\u201324","journal-title":"Parasitol Int"},{"key":"4347_CR19","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3409\/fb56_1-2.83-89","volume":"56","author":"E Jablonska","year":"2008","unstructured":"Jablonska E, Ratajczak W, Jablonski J (2008) Role of the p38 MAPK pathway in induction of iNOS expression in human leukocytes. Folia Biol 56:83\u201389","journal-title":"Folia Biol"},{"key":"4347_CR20","doi-asserted-by":"crossref","first-page":"5306","DOI":"10.4049\/jimmunol.155.11.5306","volume":"155","author":"P Jacobs","year":"1995","unstructured":"Jacobs P, Radzioch D, Stevenson MM (1995) Nitric oxide expression in the spleen, but not in the liver, correlates with resistance to blood-stage malaria in mice. J Immunol 155:5306\u20135313","journal-title":"J Immunol"},{"key":"4347_CR21","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/j.1365-3024.2007.01013.x","volume":"30","author":"V Jakobi","year":"2008","unstructured":"Jakobi V, Petry F (2008) Humoral immune response in IL-12 and IFN-\u03b3 deficient mice after infection with Cryptosporidium parvum. Parasite Immunol 30:151\u2013161","journal-title":"Parasite Immunol"},{"key":"4347_CR22","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1002\/glia.20869","volume":"57","author":"M Jana","year":"2009","unstructured":"Jana M, Dasgupta S, Pal U, Pahan K (2009) IL-12 p40 homodimer, the so-called biologically inactive molecule, induces nitric oxide synthase in microglia via IL-12R beta1. Glia 57:1553\u20131565","journal-title":"Glia"},{"key":"4347_CR23","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.neures.2009.06.006","volume":"65","author":"Y Jin","year":"2009","unstructured":"Jin Y, Choi IY, Kim C, Hong S, Kim WK (2009) Excretory-secretory products from Paragonimus westermani increase nitric oxide production in microglia in PKC-dependent and -independent manners. Neurosci Res 65:141\u2013147","journal-title":"Neurosci Res"},{"key":"4347_CR24","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1097\/01.shk.0000113314.37747.55","volume":"21","author":"W Kan","year":"2004","unstructured":"Kan W, Zhao KS, Jiang Y, Yan W, Huang Q, Wang J, Qin Q, Huang X, Wang S (2004) Lung, spleen, and kidney are the major places for inducible nitric oxide synthase expression in endotoxic shock: role of p38 mitogen-activated protein kinase in signal transduction of inducible nitric oxide synthase expression. Shock 21:281\u2013287","journal-title":"Shock"},{"key":"4347_CR25","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1210\/en.2005-0829","volume":"147","author":"E Karpuzoglu","year":"2006","unstructured":"Karpuzoglu E, Fenaux JB, Phillips RA, Lengi AJ, Elvinger F, Ansar Ahmed S (2006) Estrogen up-regulates inducible nitric oxide synthase, nitric oxide, and cyclooxygenase-2 in splenocytes activated with T cell stimulants: role of interferon-gamma. Endocrinology 147:662\u2013671","journal-title":"Endocrinology"},{"key":"4347_CR26","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.micinf.2004.01.003","volume":"6","author":"K Kawakami","year":"2004","unstructured":"Kawakami K, Kinjo Y, Uezu K, Miyagi K, Kinjo T, Yara S, Koguchi Y, Miyazato A, Shibuya K, Iwakura Y, Takeda K, Akira S, Saito A (2004) Interferon-gamma production and host protective response against Mycobacterium tuberculosis in mice lacking both IL-12p40 and IL-18. Microbes Infect 6:339\u2013349","journal-title":"Microbes Infect"},{"key":"4347_CR27","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.npep.2009.12.004","volume":"44","author":"F Kuhr","year":"2010","unstructured":"Kuhr F, Lowry J, Zhang Y, Brovkovych V, Skidgel RA (2010) Differential regulation of inducible and endothelial nitric oxide synthase by kinin B1 and B2 receptors. Neuropeptides 44:145\u2013154","journal-title":"Neuropeptides"},{"key":"4347_CR28","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S1473-3099(04)01252-6","volume":"5","author":"ZR Lun","year":"2005","unstructured":"Lun ZR, Gasser RB, Lai DH, Li AX, Zhu XQ, Yu XB, Fang YY (2005) Clonorchiasis: a key foodborne zoonosis in China. Lancet Infect Dis 5:31\u201341","journal-title":"Lancet Infect Dis"},{"key":"4347_CR29","author":"Q Mao","year":"2014","unstructured":"Mao Q, Xie Z, Wang X, Chen W, Ren M, Shang M, Lei H, Tian Y, Li S, Liang P, Chen T, Liang C, Xu J, Li X, Huang Y, Yu X (2014) Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells. Parasitol Res. doi: 10.1007\/s00436-014-4230-0","journal-title":"Parasitol Res"},{"key":"4347_CR30","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1111\/j.1365-2567.2006.02438.x","volume":"119","author":"AB Mullen","year":"2006","unstructured":"Mullen AB, Lawrence CE, McFarlane E, Wei XQ, Carter KC (2006) Endogenous interleukin-18 is involved in immunity to Leishmania donovani but its absence does not adversely influence the therapeutic activity of sodium stibogluconate. Immunology 119:348\u2013354","journal-title":"Immunology"},{"key":"4347_CR31","first-page":"440","volume":"13","author":"H Nahrevanian","year":"2009","unstructured":"Nahrevanian H (2009) Involvement of nitric oxide and its up\/down stream molecules in the immunity against parasitic infections. BJID 13:440\u2013448","journal-title":"BJID"},{"key":"4347_CR32","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.ijpara.2011.11.001","volume":"42","author":"J-H Nam","year":"2012","unstructured":"Nam J-H, Moon JH, Kim IK, Lee M-R, Hong S-J, Ahn JH, Chung JW, Pak JH (2012) Free radicals enzymatically triggered by Clonorchis sinensis excretory-secretory products cause NF-\u03baB-mediated inflammation in human cholangiocarcinoma cells. Int J Parasitol 42:103\u2013113","journal-title":"Int J Parasitol"},{"key":"4347_CR33","doi-asserted-by":"crossref","first-page":"7899","DOI":"10.1074\/jbc.M008262200","volume":"276","author":"K Pahan","year":"2001","unstructured":"Pahan K, Sheikh FG, Liu X, Hilger S, McKinney M, Petro TM (2001) Induction of nitric-oxide synthase and activation of NF-kappa B by interleukin-12 p40 in microglial cells. J Biol Chem 276:7899\u20137905","journal-title":"J Biol Chem"},{"key":"4347_CR34","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1002\/jcb.22368","volume":"108","author":"JH Pak","year":"2009","unstructured":"Pak JH, Moon JH, Hwang S-J, Cho S-H, Seo S-B, Kim T-S (2009) Proteomic analysis of differentially expressed proteins in human cholangiocarcinoma cells treated with Clonorchis sinensis excretory-secretory products. J Cell Biochem 108:1376\u20131388","journal-title":"J Cell Biochem"},{"key":"4347_CR35","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/2049-9957-1-4","volume":"1","author":"MB Qian","year":"2012","unstructured":"Qian MB, Chen YD, Liang S, Yang GJ, Zhou XN (2012) The global epidemiology of clonorchiasis and its relation with cholangiocarcinoma. Infect Dis Poverty 1:4. doi: 10.1186\/2049-9957-1-4","journal-title":"Infect Dis Poverty"},{"key":"4347_CR36","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1079\/JOH2005300","volume":"79","author":"HJ Rim","year":"2005","unstructured":"Rim HJ (2005) Clonorchiasis: an update. J Helminthol 79:269\u2013281","journal-title":"J Helminthol"},{"key":"4347_CR37","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1002\/eji.200323501","volume":"33","author":"CH Sadler","year":"2003","unstructured":"Sadler CH, Rutitzky LI, Stadecker MJ, Wilson RA (2003) IL-10 is crucial for the transition from acute to chronic disease stage during infection of mice with Schistosoma mansoni. Eur J Immunol 33:880\u2013888","journal-title":"Eur J Immunol"},{"key":"4347_CR38","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1182\/blood.V92.6.2093","volume":"92","author":"O Salvucci","year":"1998","unstructured":"Salvucci O, Kolb JP, Dugas B, Dugas N, Chouaib S (1998) The induction of nitric oxide by interleukin-12 and tumor necrosis factor alpha in human natural killer cells: relationship with the regulation of lytic activity. Blood 92:2093\u20132102","journal-title":"Blood"},{"key":"4347_CR39","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s13028-014-0057-z","volume":"56","author":"FP Sanches","year":"2014","unstructured":"Sanches FP, Tomokane TY, Da Matta V, Marcondes M, Corbett C, Laurenti MD (2014) Expression of inducible nitric oxide synthase in macrophages inversely correlates with parasitism of lymphoid tissues in dogs with visceral leishmaniasis. Acta Vet Scand 56:57. doi: 10.1186\/s13028-014-0057-z","journal-title":"Acta Vet Scand"},{"key":"4347_CR40","doi-asserted-by":"crossref","first-page":"3075","DOI":"10.4049\/jimmunol.166.5.3075","volume":"166","author":"H Schindler","year":"2001","unstructured":"Schindler H, Lutz MB, R\u00f6llinghoff M, Bogdan C (2001) The production of IFN-gamma by IL-12\/IL-18-activated macrophages requires STAT-4 signaling and inhibited by IL-4. J Immunol 166:3075\u20133082","journal-title":"J Immunol"},{"key":"4347_CR41","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1111\/j.1349-7006.2009.01458.x","volume":"101","author":"HR Shin","year":"2010","unstructured":"Shin HR, Oh JK, Masuyer E, Curado MP, Bouvard V, Fang YY, Wiangnon S, Sripa B, Hong ST (2010) Epidemiology of cholangiocarcinoma: an update focusing on risk factors. Cancer Sci 101:579\u2013585","journal-title":"Cancer Sci"},{"key":"4347_CR42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1385\/IR:22:1:1","volume":"22","author":"VK Singh","year":"2000","unstructured":"Singh VK, Mehrotra S, Narayan P, Pandey CM, Agarwal SS (2000) Modulation of autoimmune diseases by nitric oxide. Immunol Res 22:1\u201319","journal-title":"Immunol Res"},{"key":"4347_CR43","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/jhbp.62","volume":"21","author":"P Sithithaworn","year":"2014","unstructured":"Sithithaworn P, Yongvanit P, Duenngai K, Kiatsopit N, Pairojkul C (2014) Roles of liver fluke infection as risk factor for cholangiocarcinoma. J Hepatobiliary Pancreat Sci 21:301\u2013308","journal-title":"J Hepatobiliary Pancreat Sci"},{"key":"4347_CR44","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1038\/nrd2222","volume":"6","author":"C Szab\u00f3","year":"2007","unstructured":"Szab\u00f3 C, Ischiropoulos H, Radi R (2007) Peroxynitrite: biochemistry, pathophysiology and development of therapeutics. Nat Rev Drug Discov 6:662\u2013680","journal-title":"Nat Rev Drug Discov"},{"key":"4347_CR45","doi-asserted-by":"crossref","first-page":"3534","DOI":"10.3748\/wjg.v19.i23.3534","volume":"19","author":"G Tarantino","year":"2013","unstructured":"Tarantino G, Scalera A, Finelli C (2013) Liver-spleen axis: intersection between immunity, infections and metabolism. World J Gastroenterol 19:3534\u20133542","journal-title":"World J Gastroenterol"},{"key":"4347_CR46","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/S1567-5769(01)00093-5","volume":"1","author":"RC Veen van der","year":"2001","unstructured":"van der Veen RC (2001) Nitric oxide and T helper cell immunity. Int Immunopharmacol 1:1491\u20131500","journal-title":"Int Immunopharmacol"},{"key":"4347_CR47","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.exppara.2008.09.023","volume":"121","author":"PM Vieira","year":"2009","unstructured":"Vieira PM, Francisco AF, de Souza SM, Malaquias LC, Reis AB, Giunchetti RC, Veloso VM, de Lana M, Tafuri WL, Carneiro CM (2009) Trypanosoma cruzi: serum levels of nitric oxide and expression of inducible nitric oxide synthase in myocardium and spleen of dogs in the acute stage of infection with metacyclic or blood trypomastigotes. Exp Parasitol 121:76\u201382","journal-title":"Exp Parasitol"},{"key":"4347_CR48","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1007\/s00436-002-0631-6","volume":"88","author":"E Wandurska-Nowak","year":"2002","unstructured":"Wandurska-Nowak E, Wi\u015bniewska J (2002) Release of nitric oxide during experimental trichinellosis in mice. Parasitol Res 88:708\u2013711","journal-title":"Parasitol Res"},{"key":"4347_CR49","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1046\/j.1365-2168.2002.02143.x","volume":"89","author":"P Watanapa","year":"2002","unstructured":"Watanapa P, Watanapa WB (2002) Liver fluke-associated cholangiocarcinoma. Br J Surg 89:962\u2013970","journal-title":"Br J Surg"},{"key":"4347_CR50","doi-asserted-by":"crossref","first-page":"5520","DOI":"10.1128\/IAI.66.11.5520-5526.1998","volume":"66","author":"BA Wu-Hsieh","year":"1998","unstructured":"Wu-Hsieh BA, Chen W, Lee HJ (1998) Nitric oxide synthase expression in macrophages of Histoplasma capsulatum-infected mice is associated with splenocyte apoptosis and unresponsiveness. Infect Immun 66:5520\u20135526","journal-title":"Infect Immun"},{"key":"4347_CR51","first-page":"238","volume":"31","author":"Q Yang","year":"2013","unstructured":"Yang Q, Shen J (2013) Pathogen associate molecular patterns of parasites. Chin J Parasitol Parasit Dis (in Chinese) 31:238\u2013241","journal-title":"Chin J Parasitol Parasit Dis (in Chinese)"},{"key":"4347_CR52","first-page":"28","volume":"15","author":"Q Yang","year":"2008","unstructured":"Yang Q, Wei P (2008) Pathogen associate molecular patterns of virus. Int J Virol (in Chinese) 15:28\u201331","journal-title":"Int J Virol (in Chinese)"},{"key":"4347_CR53","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.vetimm.2011.03.021","volume":"142","author":"Q Yang","year":"2011","unstructured":"Yang Q, Wei P, Chen H (2011) Cytokine responses and inducible nitrous oxide synthase expression patterns in neonatal chicken brain microglia infected with very virulent Marek\u2019s disease virus strain YL040920. Vet Immunol Immunopathol 142:14\u201324","journal-title":"Vet Immunol Immunopathol"},{"key":"4347_CR54","first-page":"217","volume":"32","author":"Q Yang","year":"2014","unstructured":"Yang Q, Shen J, Jiang Z, Yang Y, Li H, Chen Y, Zhou X (2014) Differentiation of Clonorchis sinensis metacercariae using PCR targeting ribosomal DNA ITS regions and COX1 gene. Chin J Parasitol Parasit Dis (in Chinese) 32:217\u2013220","journal-title":"Chin J Parasitol Parasit Dis (in Chinese)"},{"key":"4347_CR55","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.cyto.2013.07.027","volume":"64","author":"JY Yim","year":"2013","unstructured":"Yim JY, Yang SJ, Yim JM, Song MY, Rho HW, Yim SK, Han YH, Jeon SY, Kim HS, Yhim HY, Lee NR, Song EK, Kwak JY, Sohn MH, Yim CY (2013) Lymphocyte-mediated macrophage apoptosis during IL-12 stimulation. Cytokine 64:62\u201370","journal-title":"Cytokine"},{"key":"4347_CR56","first-page":"883","volume":"32","author":"C-Y Zhang","year":"2005","unstructured":"Zhang C-Y, Xu S-G, Huang X-X (2005) A novel and convenient relative quantitative method of fluorescence real time RT-PCR assay based on slope of standard curve. Prog Biochem Biophys (in Chinese) 32:883\u2013888","journal-title":"Prog Biochem Biophys (in Chinese)"}],"container-title":["Parasitology Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00436-015-4347-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-015-4347-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-015-4347-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,6]],"date-time":"2023-08-06T01:11:55Z","timestamp":1691284315000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00436-015-4347-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,17]]},"references-count":56,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["4347"],"URL":"https:\/\/doi.org\/10.1007\/s00436-015-4347-9","relation":{},"ISSN":["0932-0113","1432-1955"],"issn-type":[{"value":"0932-0113","type":"print"},{"value":"1432-1955","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,17]]}}}