{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T20:19:53Z","timestamp":1783109993567,"version":"3.54.6"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2015,10,15]],"date-time":"2015-10-15T00:00:00Z","timestamp":1444867200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81471981"],"award-info":[{"award-number":["81471981"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81271860"],"award-info":[{"award-number":["81271860"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Parasitol Res"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1007\/s00436-015-4779-2","type":"journal-article","created":{"date-parts":[[2015,10,15]],"date-time":"2015-10-15T01:16:53Z","timestamp":1444871813000},"page":"615-622","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Screening and characterization of early diagnostic antigens in excretory\u2013secretory proteins from Trichinella spiralis intestinal infective larvae by immunoproteomics"],"prefix":"10.1007","volume":"115","author":[{"given":"Ruo Dan","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang Yang","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li Ang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie Feng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun Ying","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ge Ge","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong Quan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,10,15]]},"reference":[{"key":"4779_CR1","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.vetpar.2008.10.049","volume":"159","author":"F Bolas-Fernandez","year":"2009","unstructured":"Bolas-Fernandez F, Dea-Ayuela MA, Connolly B, Robinson MW (2009) Micro-environmental conditions modulate protein secretion and infectivity of the Trichinella spiralis L1 larva. Vet Parasitol 159:236\u2013239. doi: 10.1016\/j.vetpar. 2008.10.049","journal-title":"Vet Parasitol"},{"key":"4779_CR2","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"MM Bradford","year":"1976","unstructured":"Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248\u2013254","journal-title":"Anal Biochem"},{"key":"4779_CR3","doi-asserted-by":"crossref","first-page":"186","DOI":"10.4269\/ajtmh.1990.43.186","volume":"43","author":"F Bruschi","year":"1990","unstructured":"Bruschi F, Tassi C, Pozio E (1990) Parasite-specific antibody response in Trichinella sp. 3 human infection: a one year follow-up. Am J Trop Med Hyg 43:186\u2013193","journal-title":"Am J Trop Med Hyg"},{"key":"4779_CR4","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/978-1-4613-3578-8","volume-title":"Trichinella and trichinosis","author":"WC Campbell","year":"1983","unstructured":"Campbell WC (1983) Trichinella and trichinosis. Plenum Press, New York, p 75"},{"key":"4779_CR5","doi-asserted-by":"crossref","first-page":"e3034","DOI":"10.1371\/journal.pntd.0003034","volume":"8","author":"JV Conlan","year":"2014","unstructured":"Conlan JV, Vongxay K, Khamlome B, Gomez-Morales MA, Pozio E, Blacksell SD et al (2014) Patterns and risks of Trichinella infection in humans and pigs in northern Laos. PLoS Negl Trop Dis 8:e3034. doi: 10.1371\/journal.pntd.0003034","journal-title":"PLoS Negl Trop Dis"},{"key":"4779_CR6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.actatropica.2011.02.005","volume":"118","author":"J Cui","year":"2011","unstructured":"Cui J, Wang ZQ, Xu BL (2011) The epidemiology of human trichinellosis in China during 2004\u20132009. Acta Trop 118:1\u20135. doi: 10.1016\/j.actatropica.2011.02.005","journal-title":"Acta Trop"},{"key":"4779_CR7","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.vetpar.2013.01.038","volume":"194","author":"J Cui","year":"2013","unstructured":"Cui J, Jiang P, Liu LN, Wang ZQ (2013a) Survey of Trichinella infections in domestic pigs from northern and eastern Henan, China. Vet Parasitol 194:133\u2013135. doi: 10.1016\/j.vetpar.2013.01.038","journal-title":"Vet Parasitol"},{"key":"4779_CR8","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1186\/1756-3305-6-355","volume":"6","author":"J Cui","year":"2013","unstructured":"Cui J, Liu RD, Wang L, Zhang X, Jiang P, Liu MY, Wang ZQ (2013b) Proteomic analysis of surface proteins of Trichinella spiralis muscle larvae by two-dimensional gel electrophoresis and mass spectrometry. Parasite Vector 6:355. doi: 10.1186\/1756-3305- 6\u2013355","journal-title":"Parasite Vector"},{"key":"4779_CR9","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1007\/s00436-015-4410-6","volume":"114","author":"J Cui","year":"2015","unstructured":"Cui J, Li LG, Jiang P, Liu RD, Yang X, Liu LN, Liu P, Zhang SB, Wang ZQ (2015a) Biochemical and functional characterization of the glutathione S-transferase from Trichinella spiralis. Parasitol Res 114:2007\u20132013. doi: 10.1007\/s00436-015-4410-6","journal-title":"Parasitol Res"},{"key":"4779_CR10","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.actatropica.2014.10.017","volume":"142","author":"J Cui","year":"2015","unstructured":"Cui J, Wang L, Sun GG, Liu LN, Zhang SB, Liu RD, Xi Z, Jiang P, Wang ZQ (2015b) Characterization of a Trichinella spiralis 31 kDa protein and its potential application for the serodiagnosis of trichinellosis. Acta Trop 142:57\u201363. doi: 10.1016\/j.actatropica.2014.10.017","journal-title":"Acta Trop"},{"key":"4779_CR11","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1517\/14656566.3.8.1117","volume":"3","author":"J Dupouy-Camet","year":"2002","unstructured":"Dupouy-Camet J, Kociecka W, Bruschi F, Bolas-Fernandez F, Pozio E (2002) Opinion on the diagnosis and treatment of human trichinellosis. Expert Opin Pharmacother 3:1117\u20131130. doi: 10.1517\/14656566.3.8.1117","journal-title":"Expert Opin Pharmacother"},{"key":"4779_CR12","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S0304-4017(00)00354-X","volume":"93","author":"HR Gamble","year":"2000","unstructured":"Gamble HR, Bessonov AS, Cuperlovic K, Gajadhar AA, van Knapen F, Noeckler K, Schenone H, Zhu X (2000) International commission on trichinellosis: recommendations on methods for the control of Trichinella in domestic and wild animals intended for human consumption. Vet Parasitol 93:393\u2013408","journal-title":"Vet Parasitol"},{"key":"4779_CR13","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1051\/parasite\/20041113","volume":"11","author":"HR Gamble","year":"2004","unstructured":"Gamble HR, Pozio E, Bruschi F, Nockler K, Kapel CM, Gajadhar AA (2004) International commission on trichinellosis: recommendations on the use of serological tests for the detection of Trichinella infection in animals and man. Parasite 11:3\u201313","journal-title":"Parasite"},{"key":"4779_CR14","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1128\/CMR.00026-08","volume":"22","author":"B Gottstein","year":"2009","unstructured":"Gottstein B, Pozio E, Nockler K (2009) Epidemiology, diagnosis, treatment, and control of trichinellosis. Clin Microbiol Rev 22:127\u2013145. doi: 10.1128\/CMR.00026-08","journal-title":"Clin Microbiol Rev"},{"key":"4779_CR15","first-page":"1","volume":"58","author":"ED Kennedy","year":"2009","unstructured":"Kennedy ED, Hall RL, Montgomery SP, Pyburn DG, Jones JL (2009) Trichinellosis surveillance\u2014United States, 2002\u20132007. MMWR Surveill Summ 58:1\u20137","journal-title":"MMWR Surveill Summ"},{"key":"4779_CR16","doi-asserted-by":"crossref","first-page":"233","DOI":"10.3347\/kjp.2015.53.2.233","volume":"53","author":"HJ Lee","year":"2015","unstructured":"Lee HJ, Chung OS, Kim JL, Lee SH, Yoo YB, Seo M (2015) Seroprevalence of Trichinella sp. in wild boars (Sus scrofa) from Yanggu-gun, Gangwon-do, Korea. Korean J Parasitol 53:233\u2013236. doi: 10.3347\/kjp.2015.53.2.233","journal-title":"Korean J Parasitol"},{"key":"4779_CR17","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1089\/fpd.2009.0445","volume":"7","author":"F Li","year":"2010","unstructured":"Li F, Cui J, Wang ZQ, Jiang P (2010) Sensitivity and optimization of artificial digestion in the inspection of meat for Trichinella spiralis. Foodborne Pathog Dis 7:879\u2013885. doi: 10.1089\/fpd.2009.0445","journal-title":"Foodborne Pathog Dis"},{"key":"4779_CR18","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.exppara.2012.11.001","volume":"133","author":"LN Liu","year":"2013","unstructured":"Liu LN, Jing FJ, Cui J, Fu GY, Wang ZQ (2013a) Detection of circulating antigen in serum of mice infected with Trichinella spiralis by an IgY-IgM mAb sandwich ELISA. Exp Parasitol 133:150\u2013155. doi: 10.1016\/j.exppara.2012.11.001","journal-title":"Exp Parasitol"},{"key":"4779_CR19","doi-asserted-by":"crossref","first-page":"4113","DOI":"10.1007\/s00436-013-3602-1","volume":"112","author":"RD Liu","year":"2013","unstructured":"Liu RD, Wang ZQ, Wang L, Long SR, Ren HJ, Cui J (2013b) Analysis of differentially expressed genes of Trichinella spiralis larvae activated by bile and cultured with intestinal epithelial cells using real-time PCR. Parasitol Res 112:4113\u20134120. doi: 10.1007\/s00436-013-3602-1","journal-title":"Parasitol Res"},{"key":"4779_CR20","first-page":"579","volume":"31","author":"RD Liu","year":"2014","unstructured":"Liu RD, Cui J, Wang L, Long SR, Zhang X, Liu MY, Wang ZQ (2014a) Identification of surface proteins of Trichinella spiralis muscle larvae using immunoproteomics. Trop Biomed 31:579\u2013591","journal-title":"Trop Biomed"},{"key":"4779_CR21","first-page":"1","volume":"141","author":"XD Liu","year":"2014","unstructured":"Liu XD, Wang XL, Bai X, Liu XL, Wu XP, Zhao Y et al (2014b) Oral administration with attenuated salmonella encoding a Trichinella cystatin-like protein elicited host immunity. Exp Parasitol 141:1\u201311. doi: 10.1016\/j.exppara.2014.03.015","journal-title":"Exp Parasitol"},{"key":"4779_CR22","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1007\/s00436-014-4270-5","volume":"114","author":"LN Liu","year":"2015","unstructured":"Liu LN, Zhang X, Jiang P, Liu RD, Zhou J, He RZ, Cui J, Wang ZQ (2015a) Serodiagnosis of sparganosis by ELISA using recombinant cysteine protease of Spirometra erinaceieuropaei spargana. Parasitol Res 114:753\u2013757. doi: 10.1007\/s00436-014- 4270\u20135","journal-title":"Parasitol Res"},{"key":"4779_CR23","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.actatropica.2015.07.002","volume":"150","author":"RD Liu","year":"2015","unstructured":"Liu RD, Cui J, Liu XL, Jiang P, Sun GG, Zhang X, Long SR, Wang L, Wang ZQ (2015b) Comparative proteomic analysis of surface proteins of Trichinella spiralis muscle larvae and intestinal infective larvae. Acta Trop 150:79\u201386. doi: 10.1016\/j.actatropica.2015.07.002","journal-title":"Acta Trop"},{"key":"4779_CR24","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/s00436-014-4299-5","volume":"114","author":"Z Lv","year":"2015","unstructured":"Lv Z, Wu Z, Zhang L, Ji P, Cai Y, Luo S, Wang H, Li H (2015) Genome mining offers a new starting point for parasitology research. Parasitol Res 114:399\u2013409. doi: 10.1007\/ s00436-014-4299-5","journal-title":"Parasitol Res"},{"key":"4779_CR25","doi-asserted-by":"crossref","first-page":"4806","DOI":"10.1128\/IAI.65.11.4806-4812.1997","volume":"65","author":"T ManWarren","year":"1997","unstructured":"ManWarren T, Gagliardo L, Geyer J, McVay C, Pearce-Kelling S, Appleton J (1997) Invasion of intestinal epithelia in vitro by the parasitic nematode Trichinella spiralis. Infect Immun 65:4806\u20134812","journal-title":"Infect Immun"},{"key":"4779_CR26","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/ng.769","volume":"43","author":"M Mitreva","year":"2011","unstructured":"Mitreva M, Jasmer DP, Zarlenga DS, Wang Z, Abubucker S, Martin J et al (2011) The draft genome of the parasitic nematode Trichinella spiralis. Nat Genet 43:228\u2013235. doi: 10.1038\/ng.769","journal-title":"Nat Genet"},{"key":"4779_CR27","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.3201\/eid1712.110896","volume":"17","author":"KD Murrell","year":"2011","unstructured":"Murrell KD, Pozio E (2011) Worldwide occurrence and impact of human trichinellosis, 1986\u20132009. Emerg Infect Dis 17:2194\u20132202. doi: 10.3201\/eid1712.110896","journal-title":"Emerg Infect Dis"},{"key":"4779_CR28","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1128\/CVI.00467-07","volume":"15","author":"I Nagano","year":"2008","unstructured":"Nagano I, Wu Z, Takahashi Y (2008) Species-specific antibody responses to the recombinant 53-kilodalton excretory and secretory proteins in mice infected with Trichinella spp. Clin Vaccine Immunol 15:468\u2013473. doi: 10.1128\/CVI.00467-07","journal-title":"Clin Vaccine Immunol"},{"key":"4779_CR29","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/s00436-008-1248-1","volume":"104","author":"I Nagano","year":"2009","unstructured":"Nagano I, Wu Z, Takahashi Y (2009) Functional genes and proteins of Trichinella spp. Parasitol Res 104:197\u2013207. doi: 10.1007\/s00436-008-1248-1","journal-title":"Parasitol Res"},{"key":"4779_CR30","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.vetpar.2009.04.034","volume":"163","author":"K Nockler","year":"2009","unstructured":"Nockler K, Reckinger S, Broglia A, Mayer-Scholl A, Bahn P (2009) Evaluation of a western blot and ELISA for the detection of anti-Trichinella-IgG in pig sera. Vet Parasitol 163:341\u2013347. doi: 10.1016\/j.vetpar.2009.04.034","journal-title":"Vet Parasitol"},{"key":"4779_CR31","doi-asserted-by":"crossref","first-page":"e27010","DOI":"10.1371\/journal.pone.0027010","volume":"6","author":"HJ Ren","year":"2011","unstructured":"Ren HJ, Cui J, Wang ZQ, Liu RD (2011) Normal mouse intestinal epithelial cells as a model for the in vitro invasion of Trichinella spiralis infective larvae. Plos One 6:e27010. doi: 10.1371\/journal.pone.0027010","journal-title":"Plos One"},{"key":"4779_CR32","doi-asserted-by":"crossref","first-page":"e67570","DOI":"10.1371\/journal.pone.0067570","volume":"8","author":"HJ Ren","year":"2013","unstructured":"Ren HJ, Cui J, Yang W, Liu RD, Wang ZQ (2013) Identification of differentially expressed genes of Trichinella spiralis larvae after exposure to host intestine milieu. Plos One 8:e67570. doi: 10.1371\/journal.pone.0067570","journal-title":"Plos One"},{"key":"4779_CR33","doi-asserted-by":"crossref","first-page":"4525","DOI":"10.1002\/pmic.200402057","volume":"5","author":"MW Robinson","year":"2005","unstructured":"Robinson MW, Connolly B (2005) Proteomic analysis of the excretory-secretory proteins of the Trichinella spiralis L1 larva, a nematode parasite of skeletal muscle. Proteomics 5:4525\u20134532. doi: 10.1002\/pmic.200402057","journal-title":"Proteomics"},{"key":"4779_CR34","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.molbiopara.2006.09.008","volume":"151","author":"MW Robinson","year":"2007","unstructured":"Robinson MW, Massie DH, Connolly B (2007) Secretion and processing of a novel multi-domain cystatin-like protein by intracellular stages of Trichinella spiralis. Mol Biochem Parasitol 151:9\u201317. doi: 10.1016\/j.molbiopara.2006.09.008","journal-title":"Mol Biochem Parasitol"},{"key":"4779_CR35","author":"GG Sun","year":"2015","unstructured":"Sun GG, Liu RD, Wang ZQ, Jiang P, Wang L, Liu XL, Liu CY, Zhang X, Cui J (2015) New diagnostic antigens for early trichinellosis: the excretory\u2013secretory antigens of Trichinella spiralis intestinal infective larvae. Parasitol Res. doi: 10.1007\/s00436- 015-4709-3","journal-title":"Parasitol Res"},{"key":"4779_CR36","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/s13071-015-0689-5","volume":"8","author":"B Tang","year":"2015","unstructured":"Tang B, Liu M, Wang L, Yu S, Shi H, Boireau P, Cozma V, Wu X, Liu X (2015) Characterisation of a high-frequency gene encoding a strongly antigenic cystatin-like protein from Trichinella spiralis at its early invasion stage. Parasite Vector 8:78. doi: 10.1186\/s13071-015-0689-5","journal-title":"Parasite Vector"},{"key":"4779_CR37","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.4269\/ajtmh.14-0570","volume":"92","author":"N De Van","year":"2015","unstructured":"Van De N, Thi Nga V, Dorny P, Vu Trung N, Ngoc Minh P, Trung Dung D, Pozio E (2015) Trichinellosis in Vietnam. Am J Trop Med Hyg 92:1265\u20131270. doi: 10.4269\/ajtmh.14\u20130570","journal-title":"Am J Trop Med Hyg"},{"key":"4779_CR38","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0001-706X(98)00072-2","volume":"71","author":"ZQ Wang","year":"1998","unstructured":"Wang ZQ, Cui J, Wu F, Mao FR, Jin XX (1998) Epidemiological, clinical and serological studies on trichinellosis in Henan province, China. Acta Trop 71:255\u2013268","journal-title":"Acta Trop"},{"key":"4779_CR39","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1007\/s00436-010-2102-9","volume":"108","author":"SW Wang","year":"2011","unstructured":"Wang SW, Wang ZQ, Cui J (2011) Protein change of intestinal epithelial cells induced in vitro by Trichinella spiralis infective larvae. Parasitol Res 108:593\u2013599. doi: 10.1007\/s00436- 010-2102-9","journal-title":"Parasitol Res"},{"key":"4779_CR40","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1016\/j.jprot.2012.02.005","volume":"75","author":"ZQ Wang","year":"2012","unstructured":"Wang ZQ, Wang L, Cui J (2012) Proteomic analysis of Trichinella spiralis proteins in intestinal epithelial cells after culture with their larvae by shotgun LC-MS\/MS approach. J Proteome 75:2375\u20132383. doi: 10.1016\/j.jprot.2012.02.005","journal-title":"J Proteome"},{"key":"4779_CR41","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.exppara.2013.03.004","volume":"134","author":"B Wang","year":"2013","unstructured":"Wang B, Wang ZQ, Jin J, Ren HJ, Liu LN, Cui J (2013a) Cloning, expression and characterization of a Trichinella spiralis serine protease gene encoding a 35.5 kDa protein. Exp Parasitol 134:148\u2013154. doi: 10.1016\/j.exppara.2013.03.004","journal-title":"Exp Parasitol"},{"key":"4779_CR42","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.vetpar.2013.01.045","volume":"194","author":"L Wang","year":"2013","unstructured":"Wang L, Wang ZQ, Cui J (2013b) Proteomic analysis of the changed proteins of Trichinella spiralis infective larvae after co-culture in vitro with intestinal epithelial cells. Vet Parasitol 194:160\u2013163. doi: 10.1016\/j.vetpar.2013.01.045","journal-title":"Vet Parasitol"},{"key":"4779_CR43","first-page":"139745","volume":"2013","author":"L Wang","year":"2013","unstructured":"Wang L, Wang ZQ, Hu DD, Cui J (2013c) Proteomic analysis of Trichinella spiralis muscle larval excretory-secretory proteins recognized by early infection sera. BioMed Res Int 2013:139745. doi: 10.1155\/2013\/139745","journal-title":"BioMed Res Int"},{"key":"4779_CR44","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1756-3305-7-40","volume":"7","author":"L Wang","year":"2014","unstructured":"Wang L, Cui J, Hu DD, Liu RD, Wang ZQ (2014) Identification of early diagnostic antigens from major excretory-secretory proteins of Trichinella spiralis muscle larvae using immunoproteomics. Parasite Vector 7:40. doi: 10.1186\/1756-3305-7-40","journal-title":"Parasite Vector"},{"key":"4779_CR45","doi-asserted-by":"crossref","first-page":"3551","DOI":"10.1007\/s00436-015-4650-5","volume":"114","author":"ZQ Wang","year":"2015","unstructured":"Wang ZQ, Zhang SB, Jiang P, Liu RD, Long SR, Zhang X, Ren HJ, Cui J (2015) The siRNA-mediated silencing of Trichinella spiralis nudix hydrolase results in reduction of larval infectivity. Parasitol Res 114:3551\u20133557. doi: 10.1007\/s00436-015-4650-5","journal-title":"Parasitol Res"},{"key":"4779_CR46","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/85686","volume":"19","author":"MP Washburn","year":"2001","unstructured":"Washburn MP, Wolters D, Yates JR 3rd (2001) Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat Biotechnol 19:242\u2013247. doi: 10.1038\/85686","journal-title":"Nat Biotechnol"},{"issue":"Suppl 1","key":"4779_CR47","first-page":"1","volume":"64","author":"NO Wilson","year":"2015","unstructured":"Wilson NO, Hall RL, Montgomery SP, Jones JL (2015) Trichinellosis surveillance\u2014United States, 2008\u20132012. MMWR Surveill Summ 64(Suppl 1):1\u20138","journal-title":"MMWR Surveill Summ"},{"key":"4779_CR48","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.vetpar.2008.10.035","volume":"159","author":"XP Wu","year":"2009","unstructured":"Wu XP, Fu BQ, Wang XL, Yu L, Yu SY, Deng HK et al (2009) Identification of antigenic genes in Trichinella spiralis by immunoscreening of cDNA libraries. Vet Parasitol 159:272\u2013275. doi: 10.1016\/j.vetpar.2008.10.035","journal-title":"Vet Parasitol"},{"key":"4779_CR49","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s13071-015-0641-8","volume":"8","author":"J Yang","year":"2015","unstructured":"Yang J, Pan W, Sun X, Zhao X, Yuan G, Sun Q, Huang J, Zhu X (2015) Immunoproteomic profile of Trichinella spiralis adult worm proteins recognized by early infection sera. Parasite Vector 8:20. doi: 10.1186\/s13071-015-0641-8","journal-title":"Parasite Vector"},{"key":"4779_CR50","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/0166-6851(95)00071-8","volume":"72","author":"DS Zarlenga","year":"1995","unstructured":"Zarlenga DS, Gamble HR (1995) Molecular cloning and expression of an immunodominant 53-kDa excretory-secretory antigen from Trichinella spiralis muscle larvae. Mol Biochem Parasitol 72:253","journal-title":"Mol Biochem Parasitol"},{"key":"4779_CR51","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1093\/bioinformatics\/17.9.847","volume":"17","author":"EM Zdobnov","year":"2001","unstructured":"Zdobnov EM, Apweiler R (2001) InterProScan\u2014an integration platform for the signature-recognition methods in InterPro. Bioinformatics 17:847\u2013848. doi: 10.1093\/bioinformatics\/17.9.847","journal-title":"Bioinformatics"}],"container-title":["Parasitology Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-015-4779-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00436-015-4779-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-015-4779-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,9]],"date-time":"2020-09-09T20:04:16Z","timestamp":1599681856000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00436-015-4779-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,15]]},"references-count":51,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["4779"],"URL":"https:\/\/doi.org\/10.1007\/s00436-015-4779-2","relation":{},"ISSN":["0932-0113","1432-1955"],"issn-type":[{"value":"0932-0113","type":"print"},{"value":"1432-1955","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10,15]]}}}