{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T13:48:47Z","timestamp":1771336127399,"version":"3.50.1"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2016,10,3]],"date-time":"2016-10-03T00:00:00Z","timestamp":1475452800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Karl-Enigk-Stiftung"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Parasitol Res"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1007\/s00436-016-5268-y","type":"journal-article","created":{"date-parts":[[2016,10,3]],"date-time":"2016-10-03T02:30:57Z","timestamp":1475461857000},"page":"123-131","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Replication of Toxoplasma gondii in chicken erythrocytes and thrombocytes compared to macrophages"],"prefix":"10.1007","volume":"116","author":[{"given":"Irene","family":"Malkwitz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Berndt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Runhui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arwid","family":"Daugschies","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berit","family":"Bangoura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,10,3]]},"reference":[{"key":"5268_CR1","doi-asserted-by":"crossref","first-page":"649","DOI":"10.3389\/fimmu.2014.00649","volume":"5","author":"A Assinger","year":"2014","unstructured":"Assinger A (2014) Platelets and infection - an emerging role of platelets in viral infection. Front Immunol 5:649","journal-title":"Front Immunol"},{"key":"5268_CR2","doi-asserted-by":"crossref","unstructured":"Berndt A, Wilhelm A, Jugert C, Pieper J, Sachse K, Methner U (2007) Chicken cecum immune response to Salmonella enterica serovars of different levels of invasiveness. Infect Immun 75(12):5993\u20136007","DOI":"10.1128\/IAI.00695-07"},{"key":"5268_CR3","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/nm1565","volume":"13","author":"SR Clark","year":"2007","unstructured":"Clark SR, Ma AC, Tavener SA (2007) Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Net Med 13:463\u2013469","journal-title":"Net Med"},{"key":"5268_CR4","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1016\/j.thromres.2014.09.032","volume":"134","author":"AA Da\u2019dara","year":"2014","unstructured":"Da\u2019dara AA, Skelly PJ (2014) Schistosomes versus platelets. Thromb Res 134:1176\u20131181","journal-title":"Thromb Res"},{"key":"5268_CR5","first-page":"271","volume":"30","author":"RA Damatta","year":"1998","unstructured":"Damatta RA, Seabra SH, de Souza W (1998) Further studies on the phagocytic capacity of chicken thrombocytes. J Submicrosc Cytol Pathol 30:271\u2013277","journal-title":"J Submicrosc Cytol Pathol"},{"key":"5268_CR6","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1054\/tice.1999.0002","volume":"31","author":"RA Damatta","year":"1999","unstructured":"Damatta RA, Manh\u00e3es L, Lassounskaia E, de Souza W (1999) Chicken thrombocytes in culture: lymphocyte-conditioned medium delays apoptosis. Tissue Cell 31:255\u2013263","journal-title":"Tissue Cell"},{"key":"5268_CR7","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1469-0691.2005.01332.x","volume":"12","author":"B Edvinsson","year":"2006","unstructured":"Edvinsson B, Lappalainen M, Eveng\u00e5rd B (2006) ESCMID Study Group for Toxoplasmosis. Real-time PCR targeting a 529-bp repeat element for diagnosis of toxoplasmosis. Clin Microbiol Infect 12:131\u2013136","journal-title":"Clin Microbiol Infect"},{"key":"5268_CR8","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1093\/infdis\/jiu355","volume":"210","author":"Y Feng","year":"2014","unstructured":"Feng Y, Dorhoi A, Mollenkopf HJ, Yin H, Dong Z, Mao L, Zhou J, Bi A, Weber S, Maertzdorf J, Chen G, Chen Y, Kaufmann SH (2014) Platelets direct monocyte differentiation into epithelioid-like multinucleated giant foam cells with suppressive capacity upon mycobacterial stimulation. J Infect Dis 210:1700\u20131710","journal-title":"J Infect Dis"},{"key":"5268_CR9","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.dci.2014.11.019","volume":"49","author":"F Ferdous","year":"2015","unstructured":"Ferdous F, Scott T (2015) Bacterial and viral induction of chicken thrombocyte inflammatory responses. Dev Comp Immunol 49:225\u2013230","journal-title":"Dev Comp Immunol"},{"key":"5268_CR10","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.tvjl.2015.05.008","volume":"205","author":"A Goddard","year":"2015","unstructured":"Goddard A, Leisewitz AL, Kristensen AT, Schoeman JP (2015) Platelet activation and platelet-leukocyte interaction in dogs naturally infected with Babesia rossi. Vet J 205:387\u2013392","journal-title":"Vet J"},{"key":"5268_CR11","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1093\/ps\/83.5.776","volume":"83","author":"LV Guillermo","year":"2004","unstructured":"Guillermo LV, Damatta RA (2004) Nitric oxide inhibition after Toxoplasma gondii infection of chicken macrophage cell lines. Poult Sci 83:776\u2013782","journal-title":"Poult Sci"},{"key":"5268_CR12","first-page":"104","volume":"18","author":"C Hess","year":"2003","unstructured":"Hess C, Schifferli JA (2003) Immune adherence revisited: novel players in an old game. News Physiol Sci 18:104\u2013108","journal-title":"News Physiol Sci"},{"key":"5268_CR13","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.dci.2005.02.002","volume":"29","author":"MH Kogut","year":"2005","unstructured":"Kogut MH, Iqbal M, He H, Philbin V, Kaiser P, Smith A (2005) Expression and function of Toll-like receptors in chicken heterophils. Dev Comp Immunol 29:791\u2013807","journal-title":"Dev Comp Immunol"},{"key":"5268_CR14","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/BF02652572","volume":"1","author":"KM Lam","year":"1997","unstructured":"Lam KM (1997) Activation, adhesion, migration and death of chicken thrombocytes. Comp Haem Int 1:81\u201387","journal-title":"Comp Haem Int"},{"key":"5268_CR15","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1083\/jcb.200105058","volume":"154","author":"S Lindemann","year":"2001","unstructured":"Lindemann S, Tolley ND, Dixon DA, McIntyre TM, Prescott SM (2001) Activated platelets mediate inflammatory signaling by regulated interleukin 1beta synthesis. J Cell Biol 154:485\u2013490","journal-title":"J Cell Biol"},{"key":"5268_CR16","doi-asserted-by":"crossref","first-page":"806","DOI":"10.2307\/3281034","volume":"69","author":"MN Lunde","year":"1983","unstructured":"Lunde MN, Jacobs L (1983) Antigenic differences between endozoites and cystozoites of Toxoplasma gondii. J Parasitol 69:806\u2013808","journal-title":"J Parasitol"},{"key":"5268_CR17","doi-asserted-by":"crossref","first-page":"3115","DOI":"10.1007\/s00436-013-3486-0","volume":"112","author":"I Malkwitz","year":"2013","unstructured":"Malkwitz I, Berndt A, Daugschies A, Bangoura B (2013) Long-term investigations on Toxoplasma gondii-infected primary chicken macrophages. Parasitol Res 112:3115\u20133122","journal-title":"Parasitol Res"},{"issue":"10","key":"5268_CR18","doi-asserted-by":"crossref","first-page":"e26998","DOI":"10.1371\/journal.pone.0026998","volume":"6","author":"D Morera","year":"2011","unstructured":"Morera D, Roher N, Ribas L, Balasch JC, Do\u00f1ate C, Callol A, Bolta\u00f1a S, Roberts S, Goetz G, Goetz FW, Mackenzie SA (2011) RNA-Seq reveals an integrated immune response in nucleated erythrocytes. PLoS One 6(10):e26998","journal-title":"PLoS One"},{"issue":"3077","key":"5268_CR19","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1126\/science.118.3077.733","volume":"118","author":"RA Nelson Jr","year":"1953","unstructured":"Nelson RA Jr (1953) The immune-adherence phenomenon; an immunologically specific reaction between microorganisms and erythrocytes leading to enhanced phagocytosis. Science 118(3077):733\u2013737","journal-title":"Science"},{"issue":"10","key":"5268_CR20","doi-asserted-by":"crossref","first-page":"e26369","DOI":"10.1371\/journal.pone.0026369","volume":"6","author":"YC Ong","year":"2011","unstructured":"Ong YC, Boyle JP, Boothroyd JC (2011) Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts. PLoS One 6(10):e26369","journal-title":"PLoS One"},{"key":"5268_CR21","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1080\/08923970701284664","volume":"29","author":"L Passantino","year":"2007","unstructured":"Passantino L, Massaro MA, Jirillo F, Di Modugno D, Ribaud MR, Modugno GD, Passantino GF, Jirillo E (2007) Antigenically activated avian erythrocytes release cytokine-like factors: a conserved phylogenetic function discovered in fish. Immunopharmacol Immunotoxicol 29:141\u2013152","journal-title":"Immunopharmacol Immunotoxicol"},{"key":"5268_CR22","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1046\/j.1365-2184.2001.00222.x","volume":"34","author":"B Porto","year":"2001","unstructured":"Porto B, Fonseca AM, Godinho I, Arosa FA, Porto G (2001) Human red blood cells have an enhancing effect on the relative expansion of CD8+ T lymphocytes in vitro. Cell Prolif 34:359\u2013367","journal-title":"Cell Prolif"},{"key":"5268_CR23","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1128\/IAI.00788-10","volume":"79","author":"J Pieper","year":"2011","unstructured":"Pieper J, Methner U, Berndt A (2011) Characterization of avian gamma\/delta T-cell subsets after Salmonella Typhimurium infection of chicks. Infect Immun 79:822\u2013829","journal-title":"Infect Immun"},{"key":"5268_CR24","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.vetimm.2013.02.007","volume":"153","author":"P Qu\u00e9r\u00e9","year":"2013","unstructured":"Qu\u00e9r\u00e9 P, Pierre J, Hoang MD, Esnault E, Domenech J, Sibille P, Dimier-Poisson I (2013) Presence of dendritic cells in chicken spleen cell preparations and their functional interaction with the parasite Toxoplasma gondii. Vet Immunol Immunopathol 153:57\u201369","journal-title":"Vet Immunol Immunopathol"},{"key":"5268_CR25","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1073\/pnas.88.4.1359","volume":"88","author":"J Salomonsen","year":"1991","unstructured":"Salomonsen J, Dunon D, Skj\u00f8dt K, Thorpe D, Vainio O, Kaufman J (1991) Chicken major histocompatibility complex-encoded B-G antigens are found on many cell types that are important for the immune system. Proc Natl Acad Sci U S A 88:1359\u20131363","journal-title":"Proc Natl Acad Sci U S A"},{"key":"5268_CR26","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/BF00390369","volume":"55","author":"E Schupp","year":"1978","unstructured":"Schupp E, Michel R, Raether W, Niemeitz H, Uphoff M (1978) Invasion of erythrocytes by Toxoplasma gondii. Z Parasitenkd 55:189\u2013193","journal-title":"Z Parasitenkd"},{"key":"5268_CR27","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1006\/expr.2001.4675","volume":"100","author":"SH Seabra","year":"2002","unstructured":"Seabra SH, de Souza W, Damatta RA (2002) Toxoplasma gondii partially inhibits nitric oxide production of activated murine macrophages. Exp Parasitol 100:62\u201370","journal-title":"Exp Parasitol"},{"key":"5268_CR28","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1113\/jphysiol.1983.sp014685","volume":"338","author":"TJ Simons","year":"1983","unstructured":"Simons TJ (1983) Characterization of sugar transport in the pigeon red blood cell. J Physiol 338:477\u2013499","journal-title":"J Physiol"},{"issue":"8","key":"5268_CR29","doi-asserted-by":"crossref","first-page":"e43381","DOI":"10.1371\/journal.pone.0043381","volume":"7","author":"M St Paul","year":"2012","unstructured":"St Paul M, Paolucci S, Barjesteh N, Wood RD, Schat KA, Sharif S (2012) Characterization of chicken thrombocyte responses to Toll-like receptor ligands. PLoS One 7(8):e43381","journal-title":"PLoS One"},{"key":"5268_CR30","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.rvsc.2013.01.024","volume":"95","author":"M St Paul","year":"2013","unstructured":"St Paul M, Paolucci S, Barjesteh N, Wood RD, Sharif S (2013) Chicken erythrocytes respond to Toll-like receptor ligands by up-regulating cytokine transcripts. Res Vet Sci 95:87\u201391","journal-title":"Res Vet Sci"},{"key":"5268_CR31","doi-asserted-by":"crossref","first-page":"240","DOI":"10.2307\/3280811","volume":"66","author":"K Tanabe","year":"1980","unstructured":"Tanabe K, Kimata I, Takada S (1980) Penetration of chick embryo erythrocytes by Toxoplasma gondii tachyzoites in simplified incubation media. J Parasitol 66:240\u2013244","journal-title":"J Parasitol"},{"key":"5268_CR32","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1080\/03079459994353","volume":"28","author":"P Wigley","year":"1999","unstructured":"Wigley P, Hulme SD, Barrow PA (1999) Phagocytic and oxidative burst activity of chicken thrombocytes to Salmonella. Escherichia coli and other bacteria. Avian Pathol 28:567\u2013572","journal-title":"Avian Pathol"}],"container-title":["Parasitology Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-016-5268-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00436-016-5268-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-016-5268-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,25]],"date-time":"2017-06-25T00:12:20Z","timestamp":1498349540000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00436-016-5268-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,3]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["5268"],"URL":"https:\/\/doi.org\/10.1007\/s00436-016-5268-y","relation":{},"ISSN":["0932-0113","1432-1955"],"issn-type":[{"value":"0932-0113","type":"print"},{"value":"1432-1955","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,3]]}}}