{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T20:22:24Z","timestamp":1780345344552,"version":"3.54.1"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2021,9,25]],"date-time":"2021-09-25T00:00:00Z","timestamp":1632528000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,9,25]],"date-time":"2021-09-25T00:00:00Z","timestamp":1632528000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"basic science research program through the national research foundation of korea","award":["2017R1D1A1A02018651"],"award-info":[{"award-number":["2017R1D1A1A02018651"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Parasitol Res"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1007\/s00436-021-07321-6","type":"journal-article","created":{"date-parts":[[2021,9,25]],"date-time":"2021-09-25T03:29:07Z","timestamp":1632540547000},"page":"3845-3850","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Production of a monoclonal antibody against a galactose-binding protein of Acanthamoeba castellanii and its cytotoxicity"],"prefix":"10.1007","volume":"120","author":[{"given":"Dong-Youn","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dae-Hyun","family":"Son","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul","family":"Matin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6246-2479","authenticated-orcid":false,"given":"Suk-Yul","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,9,25]]},"reference":[{"issue":"25","key":"7321_CR1","doi-asserted-by":"publisher","first-page":"15838","DOI":"10.1074\/jbc.273.25.15838","volume":"273","author":"Z Cao","year":"1998","unstructured":"Cao Z, Jefferson DM, Panjwani N (1998) Role of carbohydrate-mediated adherence in cytopathogenic mechanisms of Acanthamoeba. J Biol Chem 273(25):15838\u201315845","journal-title":"J Biol Chem"},{"issue":"2","key":"7321_CR2","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1016\/S0016-5085(00)70219-8","volume":"118","author":"XM Chen","year":"2000","unstructured":"Chen XM, LaRusso NF (2000) Mechanisms of attachment and internalization of Cryptosporidium parvum to biliary and intestinal epithelial cells. Gastroenterol 118(2):368\u2013379","journal-title":"Gastroenterol"},{"issue":"28","key":"7321_CR3","doi-asserted-by":"publisher","first-page":"29849","DOI":"10.1074\/jbc.M402334200","volume":"279","author":"M Garate","year":"2004","unstructured":"Garate M, Cao Z, Bateman E, Panjwani N (2004) Cloning and characterization of a novel mannose-binding protein of Acanthamoeba. J Biol Chem 279(28):29849\u201329905","journal-title":"J Biol Chem"},{"issue":"3","key":"7321_CR4","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1167\/iovs.05-0477","volume":"47","author":"M Garate","year":"2006","unstructured":"Garate M, Marchant J, Cubillos I, Cao Z, Khan NA, Panjwani N (2006) In vitro pathogenicity of Acanthamoeba is associated with the expression of the mannose-binding protein. Invest Ophthal Vis Sci 47(3):1056\u20131062","journal-title":"Invest Ophthal Vis Sci"},{"issue":"7","key":"7321_CR5","doi-asserted-by":"publisher","first-page":"4098","DOI":"10.1128\/IAI.73.7.4098-4105.2005","volume":"73","author":"SR Jeong","year":"2005","unstructured":"Jeong SR, Lee SC, Song KJ, Park S, Kim K, Kwon MH, Im KI, Shin HJ (2005) Expression of the nfa1 gene cloned from pathogenic Naegleria fowleri in nonpathogenic N. gruberi enhances cytotoxicity against CHO target cells in vitro. Infect Immun 73(7):4098\u20134105","journal-title":"Infect Immun"},{"issue":"3\u20134","key":"7321_CR6","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/j.ijpara.2006.10.012","volume":"37","author":"SY Jung","year":"2007","unstructured":"Jung SY, Matin A, Kim KS, Khan NA (2007) The capsule plays an important role in Escherichia coli K1 interactions with Acanthamoeba. Int J Parasitol 37(3\u20134):417\u2013423","journal-title":"Int J Parasitol"},{"key":"7321_CR7","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.exppara.2018.07.009","volume":"192","author":"AY Kang","year":"2018","unstructured":"Kang AY, Park AY, Shin HJ, Khan NA, Maciver S, Jung SY (2018) Production of a monoclonal antibody against a mannose-binding protein of Acanthamoeba culbertsoni and its localization. Exp Parasitol 192:19\u201324","journal-title":"Exp Parasitol"},{"key":"7321_CR8","doi-asserted-by":"publisher","first-page":"13901","DOI":"10.1038\/srep13901","volume":"5","author":"K Kato","year":"2015","unstructured":"Kato K, Yahata K, Dhoubhadel BG, Fujii Y, Tachibana H (2015) Novel hemagglutinating, hemolytic and cytotoxic activities of the intermediate subunit of Entamoeba histolytica lectin. Sci Rep 5:13901","journal-title":"Sci Rep"},{"issue":"4","key":"7321_CR9","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1111\/j.1574-6976.2006.00023.x","volume":"30","author":"NA Khan","year":"2006","unstructured":"Khan NA (2006) Acanthamoeba: biology and increasing importance in human health. FEMS Microbiol Rev 30(4):564\u2013595","journal-title":"FEMS Microbiol Rev"},{"issue":"2","key":"7321_CR10","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1016\/j.exppara.2012.08.007","volume":"132","author":"JH Kim","year":"2012","unstructured":"Kim JH, Matin A, Shin HJ, Park H, Yoo KT, Yuan XZ, Kim KS, Jung SY (2012) Functional roles of mannose-binding protein in the adhesion, cytotoxicity and phagocytosis of Acanthamoeba castellanii. Exp Parasitol 132(2):287\u2013292","journal-title":"Exp Parasitol"},{"issue":"5","key":"7321_CR11","doi-asserted-by":"publisher","first-page":"864","DOI":"10.1016\/j.ophtha.2008.12.029","volume":"116","author":"AS Kitzmann","year":"2009","unstructured":"Kitzmann AS, Goins KM, Sutphin JE, Wagoner MD (2009) Keratoplasty for treatment of Acanthamoeba keratitis. Ophthalmol 116(5):864\u2013869","journal-title":"Ophthalmol"},{"issue":"5259","key":"7321_CR12","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1038\/227680a0","volume":"227","author":"UK Laemmli","year":"1970","unstructured":"Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227(5259):680\u2013685","journal-title":"Nature"},{"issue":"Pt 8","key":"7321_CR13","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1099\/jmm.0.47134-0","volume":"56","author":"A Matin","year":"2007","unstructured":"Matin A, Siddiqui R, Jung SY, Kim KS, Stins M, Khan NA (2007) Balamuthia mandrillaris interactions with human brain microvascular endothelial cells in vitro. J Med Microbiol 56(Pt 8):1110\u20131115","journal-title":"J Med Microbiol"},{"issue":"4","key":"7321_CR14","doi-asserted-by":"publisher","first-page":"435","DOI":"10.15616\/BSL.2018.24.4.435","volume":"24","author":"AY Park","year":"2018","unstructured":"Park AY, Kang AY, Jung SY (2018) Protective effects of a monoclonal antibody to a mannose-binding protein of Acanthamoeba culbertsoni. Biomed Sci Lett 24(4):435\u2013438","journal-title":"Biomed Sci Lett"},{"issue":"6","key":"7321_CR15","first-page":"1","volume":"5","author":"S Ruqaiyyah","year":"2012","unstructured":"Ruqaiyyah S, Khan NA (2012) Biology and pathogenesis of Acanthamoeba. Parasites Vectors 5(6):1\u201313","journal-title":"Parasites Vectors"},{"issue":"46","key":"7321_CR16","doi-asserted-by":"publisher","first-page":"38583","DOI":"10.1074\/jbc.C500365200","volume":"280","author":"S Saouros","year":"2005","unstructured":"Saouros S, Edwards-Jones B, Reiss M, Sawmynaden K, Cota E, Simpson P, Dowse TJ, J\u00e4kle U, Ramboarina S, Shivarattan T, Matthews S, Soldati-Favre D (2005) A novel galectin-like domain from Toxoplasma gondii micronemal protein 1 assists the folding, assembly, and transport of a cell adhesion complex. J Biol Chem 280(46):38583\u201338591","journal-title":"J Biol Chem"},{"key":"7321_CR17","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.exppara.2017.09.004","volume":"183","author":"GS Seong","year":"2017","unstructured":"Seong GS, Sohn HJ, Kang H, Seo GE, Kim JH, Shin HJ (2017) Production and characterization of monoclonal antibodies against cathepsin B and cathepsin B-Like proteins of Naegleria fowleri. Exp Parasitol 183:171\u2013177","journal-title":"Exp Parasitol"},{"key":"7321_CR18","doi-asserted-by":"crossref","unstructured":"Silber AM, Marcipar IS, Roodveldt C, Cabeza Meckert P, Laguens R, Marcipar AJ. Trypanosoma cruzi: identification of a galactose-binding protein that binds to cell surface of human erythrocytes and is involved in cell invasion by the parasite. Exp Parasitol 100 4 217 225","DOI":"10.1016\/S0014-4894(02)00013-9"},{"issue":"5","key":"7321_CR19","doi-asserted-by":"publisher","first-page":"1018","DOI":"10.1016\/j.biotechadv.2016.06.002","volume":"34","author":"RS Singh","year":"2016","unstructured":"Singh RS, Walia AK, Kanwar JR (2016) Protozoa lectins and their role in host-pathogen interactions. Biotechnol Adv 34(5):1018\u20131029","journal-title":"Biotechnol Adv"}],"container-title":["Parasitology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-021-07321-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00436-021-07321-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-021-07321-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,14]],"date-time":"2021-10-14T10:18:11Z","timestamp":1634206691000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00436-021-07321-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,25]]},"references-count":19,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["7321"],"URL":"https:\/\/doi.org\/10.1007\/s00436-021-07321-6","relation":{},"ISSN":["0932-0113","1432-1955"],"issn-type":[{"value":"0932-0113","type":"print"},{"value":"1432-1955","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,25]]},"assertion":[{"value":"14 June 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 September 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 September 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}