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However, the paucity of research regarding the prevalence of<jats:italic>T. vaginalis<\/jats:italic>infection in the Tibetan area limits control efforts. We aimed to evaluate the prevalence of<jats:italic>T. vaginalis<\/jats:italic>infection in the Tibetan area by a comparison with the prevalence of<jats:italic>T. vaginalis<\/jats:italic>in Wuhan city and to unveil the potential risk factors in the Tibetan area. This descriptive, cross-sectional study was conducted among adult women attending gynecology outpatient clinics in two public hospitals (one in Shannan city of Tibet and one in Wuhan city) in China in 2020. Data were retrieved from the medical record system and laboratory information management system, including<jats:italic>T. vaginalis<\/jats:italic>infection, bacterial vaginosis, and vulvovaginal candidiasis by wet mount microscopy or nucleic acid hybridization of vaginal secretions from patients. The associations of variables associated with<jats:italic>T. vaginalis<\/jats:italic>prevalence were quantified by odds ratios with 95% confidence intervals. The overall prevalence rates of<jats:italic>T. vaginalis<\/jats:italic>infection in the Tibetan area and Wuhan city were 20.94% and 2.84%, respectively. The statistically significant factors for the higher prevalence of<jats:italic>T. vaginalis<\/jats:italic>infection in the Tibetan area included tertiary educational status (AOR: 0.36 [95% CI: 0.16\u20130.81]), yearly family income\u2009&gt;\u2009\u00a5100,000 (AOR: 0.48 [95% CI: 0.26\u20130.91]), clinical symptoms (AOR: 4.58[95% CI: 2.32\u20139.04]), and III\u2013IV grade vaginal cleanliness (AOR: 29.71 [95% CI: 3.95\u2013223.56]) in the multivariate logistic analysis. Interventions targeting improved living standards as well as women\u2019s educational level and promoting reproductive hygiene habits are recommended to contribute to the reduction in<jats:italic>T. vaginalis<\/jats:italic>infection in the Tibetan area.<\/jats:p>","DOI":"10.1007\/s00436-022-07726-x","type":"journal-article","created":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T21:31:33Z","timestamp":1669411893000},"page":"265-273","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["The prevalence and risk factors of Trichomonas vaginalis in Wuhan and the Tibetan area, China: a two-center study"],"prefix":"10.1007","volume":"122","author":[{"given":"Xiaowu","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linlin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lamu","family":"Yixi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huali","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinfeng","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shouhua","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,11,25]]},"reference":[{"key":"7726_CR1","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1080\/01443610310001604411","volume":"23","author":"AP Aboyeji","year":"2003","unstructured":"Aboyeji AP, Nwabuisi C (2003) Prevalence of sexually transmitted diseases among pregnant women in Ilorin, Nigeria. 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Ethics approval for this study was obtained from the Ethics Committee of Wuhan Union Hospital (approval number: UHCT-IEC-SOP-016\u201303-01) and was waived by the Ethics Committee of the Maternal and Child Health Hospital of Shannan city in view of the retrospective nature of the study. All procedures were performed according to the ethical standards of Helsinki Declaration.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent requirements were waived from this retrospective study by Ethics Committee, but participating clinicians still provided informed consent for participants in clinical practice.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}