{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T12:00:45Z","timestamp":1787832045554,"version":"build-2784847793"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100003093","name":"Ministry of Higher Education, Malaysia","doi-asserted-by":"publisher","award":["FRGS\/1\/2020\/SKK0\/UM\/01\/3"],"award-info":[{"award-number":["FRGS\/1\/2020\/SKK0\/UM\/01\/3"]}],"id":[{"id":"10.13039\/501100003093","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Parasitol Res"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1007\/s00436-024-08125-0","type":"journal-article","created":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T09:02:38Z","timestamp":1705654958000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Genetic polymorphism and clustering of the Plasmodium cynomolgi Duffy binding protein 1 region II of recent macaque isolates from Peninsular Malaysia"],"prefix":"10.1007","volume":"123","author":[{"given":"Eira Nurfarisha Mohd","family":"Latif","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naqib Rafieqin","family":"Noordin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahhaziq","family":"Shahari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amirah","family":"Amir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yee-Ling","family":"Lau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei-Wen","family":"Cheong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohd Lutfi","family":"Abdullah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mun Yik","family":"Fong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,19]]},"reference":[{"key":"8125_CR1","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1186\/s12936-018-2583-z","volume":"17","author":"MA Ahmed","year":"2018","unstructured":"Ahmed MA, Chu KB, Vythilingam I, Quan FS (2018) Within-population genetic diversity and population structure of Plasmodium knowlesi merozoite surface protein 1 gene from geographically distinct regions of Malaysia and Thailand. Malar J 17:442. https:\/\/doi.org\/10.1186\/s12936-018-2583-z","journal-title":"Malar J"},{"key":"8125_CR2","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1093\/oxfordjournals.molbev.a026036","volume":"16","author":"HJ Bandelt","year":"1999","unstructured":"Bandelt HJ, Forster P, R\u00f6hl A (1999) Median-joining networks for inferring intraspecific phylogenies. Mol Biol Evol 16:37\u201348. https:\/\/doi.org\/10.1093\/oxfordjournals.molbev.a026036","journal-title":"Mol Biol Evol"},{"key":"8125_CR3","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1186\/s40101-020-00247-5","volume":"39","author":"AZ Chin","year":"2020","unstructured":"Chin AZ, Maluda MCM, Jelip J et al (2020) Malaria elimination in Malaysia and the rising threat of Plasmodium knowlesi. J Physiol Anthropol 39:36. https:\/\/doi.org\/10.1186\/s40101-020-00247-5","journal-title":"J Physiol Anthropol"},{"key":"8125_CR4","volume-title":"The primate malarias","author":"GR Coatney","year":"1971","unstructured":"Coatney GR (1971) The primate malarias. US National Institute of Allergy and Infectious Diseases, USA"},{"key":"8125_CR5","doi-asserted-by":"publisher","first-page":"186","DOI":"10.4269\/ajtmh.1962.11.186","volume":"11","author":"PG Contacos","year":"1962","unstructured":"Contacos PG, Elder HA, Coatney GR et al (1962) Man to man transfer of two strains of Plasmodium cynomolgi by mosquito bite. Am J Trop Med Hyg 11:186\u2013193. https:\/\/doi.org\/10.4269\/ajtmh.1962.11.186","journal-title":"Am J Trop Med Hyg"},{"key":"8125_CR6","first-page":"1","volume":"3","author":"C Daniels","year":"1908","unstructured":"Daniels C (1908) Animal parasites in man and some of the lower animals in Malaya. Stud Inst Med Res FMS 3:1\u201313","journal-title":"Stud Inst Med Res FMS"},{"key":"8125_CR7","doi-asserted-by":"publisher","first-page":"616","DOI":"10.3201\/eid2304.161738","volume":"23","author":"PC Divis","year":"2017","unstructured":"Divis PC, Lin LC, Rovie-Ryan JJ et al (2017) Three divergent subpopulations of the malaria parasite Plasmodium knowlesi. Emerg Infect Dis 23:616\u2013624. https:\/\/doi.org\/10.3201\/eid2304.161738","journal-title":"Emerg Infect Dis"},{"key":"8125_CR8","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1186\/s12936-023-04630-2","volume":"22","author":"D Doum","year":"2023","unstructured":"Doum D, Mclver DJ, Hustedt J et al (2023) An active and targeted survey reveals asymptomatic malaria infections among high-risk populations in Mondulkiri. Cambodia Malar J 22:193. https:\/\/doi.org\/10.1186\/s12936-023-04630-2","journal-title":"Cambodia Malar J"},{"key":"8125_CR9","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1186\/s12936-015-0610-x","volume":"14","author":"MY Fong","year":"2015","unstructured":"Fong MY, Rashdi SA, Yusof R et al (2015) Distinct genetic difference between the Duffy binding protein (PkDBP\u03b1II) of Plasmodium knowlesi clinical isolates from North Borneo and Peninsular Malaysia. Malar J 14:91. https:\/\/doi.org\/10.1186\/s12936-015-0610-x","journal-title":"Malar J"},{"key":"8125_CR10","doi-asserted-by":"publisher","first-page":"e0155627","DOI":"10.1371\/journal.pone.0155627","volume":"11","author":"MY Fong","year":"2016","unstructured":"Fong MY, Rashdi SA, Yusof R et al (2016) Genetic diversity, natural selection and haplotype grouping of Plasmodium knowlesi gamma protein region II (Pk\u03b3RII): comparison with the Duffy binding protein (PkDBP\u03b1RII). PLoS ONE 11:e0155627. https:\/\/doi.org\/10.1371\/journal.pone.0155627","journal-title":"PLoS ONE"},{"key":"8125_CR11","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1007\/s12041-019-1109-y","volume":"98","author":"MY Fong","year":"2019","unstructured":"Fong MY, Lau YL, Jelip J et al (2019) Genetic characterisation of the erythrocyte-binding protein (Pk\u03b2II) of Plasmodium knowlesi isolates from Malaysia. J Genet 98:64. https:\/\/doi.org\/10.1007\/s12041-019-1109-y","journal-title":"J Genet"},{"key":"8125_CR12","doi-asserted-by":"publisher","first-page":"1413","DOI":"10.1016\/j.ijpara.2004.10.010","volume":"34","author":"D Gaur","year":"2004","unstructured":"Gaur D, Mayer DG, Miller LH (2004) Parasite ligand\u2013host receptor interactions during invasion of erythrocytes by Plasmodium merozoites. Int J Parasitol 34:1413\u20131429. https:\/\/doi.org\/10.1016\/j.ijpara.2004.10.010","journal-title":"Int J Parasitol"},{"key":"8125_CR13","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1186\/1475-2875-11-60","volume":"11","author":"HL Ju","year":"2012","unstructured":"Ju HL, Kang JM, Moon SU et al (2012) Genetic polymorphism and natural selection of Duffy binding protein of Plasmodium vivax Myanmar isolates. Malar J 11:60. https:\/\/doi.org\/10.1186\/1475-2875-11-60","journal-title":"Malar J"},{"key":"8125_CR14","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1007\/s15010-022-01952-2","volume":"51","author":"LP Kojom Foko","year":"2023","unstructured":"Kojom Foko LP, Kumar A, Hawadak J et al (2023) Plasmodium cynomolgi in humans: current knowledge and future directions of an emerging zoonotic malaria parasite. Infection 51:623\u2013640. https:\/\/doi.org\/10.1007\/s15010-022-01952-2","journal-title":"Infection"},{"key":"8125_CR15","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1182\/blood-2017-02-764787","volume":"130","author":"V Kosaisavee","year":"2017","unstructured":"Kosaisavee V, Suwanarusk R, Chua ACY et al (2017) Strict tropism for CD71(+)\/CD234(+) human reticulocytes limits the zoonotic potential of Plasmodium cynomolgi. Blood 130:1357\u20131363. https:\/\/doi.org\/10.1182\/blood-2017-02-764787","journal-title":"Blood"},{"key":"8125_CR16","doi-asserted-by":"publisher","first-page":"211","DOI":"10.4269\/ajtmh.1982.31.211","volume":"31","author":"WA Krotoski","year":"1982","unstructured":"Krotoski WA, Bray RS, Garnham PC et al (1982) Observations on early and late post-sporozoite tissue stages in primate malaria. II. The hypnozoite of Plasmodium cynomolgi bastianellii from 3 to 105 days after infection, and detection of 36- to 40-hour pre-erythrocytic forms. Am J Trop Med Hyg 31:211\u2013225. https:\/\/doi.org\/10.4269\/ajtmh.1982.31.211","journal-title":"Am J Trop Med Hyg"},{"key":"8125_CR17","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1093\/molbev\/msy096","volume":"35","author":"S Kumar","year":"2018","unstructured":"Kumar S, Stecher G, Li M, Knyaz C, Tamura K (2018) MEGA X: molecular evolutionary genetics analysis across computing platforms. Mol Biol Evol 35:1547\u20131549. https:\/\/doi.org\/10.1093\/molbev\/msy096","journal-title":"Mol Biol Evol"},{"key":"8125_CR18","doi-asserted-by":"publisher","first-page":"66","DOI":"10.47665\/tb.39.1.011","volume":"39","author":"ENM Latif","year":"2022","unstructured":"Latif ENM, Shahari S, Amir A et al (2022) Genetic diversity of Duffy binding protein 2 region II of Plasmodium cynomolgi from wild macaques in Peninsular Malaysia. Trop Biomed 39:66\u201372","journal-title":"Trop Biomed"},{"key":"8125_CR19","doi-asserted-by":"publisher","first-page":"e1002015","DOI":"10.1371\/journal.ppat.1002015","volume":"7","author":"KS Lee","year":"2011","unstructured":"Lee KS, Divis PC, Zakaria SK et al (2011) Plasmodium knowlesi: reservoir hosts and tracking the emergence in humans and macaques. PLoS Pathog 7:e1002015. https:\/\/doi.org\/10.1371\/journal.ppat.1002015","journal-title":"PLoS Pathog"},{"key":"8125_CR20","first-page":"285","volume":"84","author":"H Mulligan","year":"1935","unstructured":"Mulligan H (1935) Descriptions of two species of monkey Plasmodium isolated from Silenus irus. Archir Fur Protistenkunde 84:285\u2013314","journal-title":"Archir Fur Protistenkunde"},{"key":"8125_CR21","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/s0166-6851(97)00118-7","volume":"89","author":"D Okenu","year":"1997","unstructured":"Okenu D, Malhotra P, Lalitha PV et al (1997) Cloning and sequence analysis of a gene encoding an erythrocyte binding protein from Plasmodium cynomolgi. Mol Biochem Parasitol 89:301\u2013306. https:\/\/doi.org\/10.1016\/s0166-6851(97)00118-7","journal-title":"Mol Biochem Parasitol"},{"key":"8125_CR22","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1016\/j.meegid.2012.02.009","volume":"12","author":"MA Pacheco","year":"2012","unstructured":"Pacheco MA, Elango AP, Rahman AA et al (2012) Evidence of purifying selection on merozoite surface protein 8 (MSP8) and 10 (MSP10) in Plasmodium spp. Infect Genet Evol 12:978\u2013986. https:\/\/doi.org\/10.1016\/j.meegid.2012.02.009","journal-title":"Infect Genet Evol"},{"key":"8125_CR23","doi-asserted-by":"publisher","first-page":"e34990","DOI":"10.1371\/journal.pone.0034990","volume":"7","author":"MA Pacheco","year":"2012","unstructured":"Pacheco MA, Reid MJ, Schillaci MA et al (2012) The origin of malarial parasites in orangutans. PLoS ONE 7:e34990. https:\/\/doi.org\/10.1371\/journal.pone.0034990","journal-title":"PLoS ONE"},{"key":"8125_CR24","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/j.meegid.2016.07.040","volume":"44","author":"C Putaporntip","year":"2016","unstructured":"Putaporntip C, Kuamsab N, Jongwutiwes S (2016) Sequence diversity and positive selection at the Duffy-binding protein genes of Plasmodium knowlesi and P. cynomolgi: analysis of the complete coding sequences of Thai isolates. Infect Genet Evol 44:367\u2013375. https:\/\/doi.org\/10.1016\/j.meegid.2016.07.040","journal-title":"Infect Genet Evol"},{"key":"8125_CR25","doi-asserted-by":"publisher","first-page":"590","DOI":"10.3201\/eid2702.191660","volume":"27","author":"C Putaporntip","year":"2021","unstructured":"Putaporntip C, Kuamsab N, Pattanawong U et al (2021) Plasmodium cynomolgi co-infections among symptomatic malaria patients, Thailand. Emerg Infect Dis 27:590\u2013593. https:\/\/doi.org\/10.3201\/eid2702.191660","journal-title":"Emerg Infect Dis"},{"key":"8125_CR26","doi-asserted-by":"publisher","first-page":"1801","DOI":"10.3201\/eid2608.200343","volume":"26","author":"TN Raja","year":"2020","unstructured":"Raja TN, Hu TH, Kadir KA et al (2020) Naturally acquired human Plasmodium cynomolgi and P. knowlesi infections. Malaysian Borneo Emerg Infect Dis 26:1801\u20131809. https:\/\/doi.org\/10.3201\/eid2608.200343","journal-title":"Malaysian Borneo Emerg Infect Dis"},{"key":"8125_CR27","doi-asserted-by":"publisher","first-page":"14067","DOI":"10.1073\/pnas.96.24.14067","volume":"96","author":"A Ranjan","year":"1999","unstructured":"Ranjan A, Chitnis CE (1999) Mapping regions containing binding residues within functional domains of Plasmodium vivax and Plasmodium knowlesi erythrocyte-binding proteins. Proc Natl Acad Sci USA 96:14067\u201314072. https:\/\/doi.org\/10.1073\/pnas.96.24.14067","journal-title":"Proc Natl Acad Sci USA"},{"key":"8125_CR28","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.ympev.2014.05.013","volume":"78","author":"BL Rice","year":"2014","unstructured":"Rice BL, Acosta MM, Pacheco MA et al (2014) The origin and diversification of the merozoite surface protein 3 (msp3) multi-gene family in Plasmodium vivax and related parasites. Mol Phylogenet Evol 78:172\u2013184. https:\/\/doi.org\/10.1016\/j.ympev.2014.05.013","journal-title":"Mol Phylogenet Evol"},{"key":"8125_CR29","doi-asserted-by":"publisher","first-page":"3299","DOI":"10.1093\/molbev\/msx248","volume":"34","author":"J Rozas","year":"2017","unstructured":"Rozas J, Ferrer-Mata A, S\u00e1nchez-DelBarrio JC et al (2017) DnaSP 6: DNA sequence polymorphism analysis of large data sets. Mol Biol Evol 34:3299\u20133302. https:\/\/doi.org\/10.1093\/molbev\/msx248","journal-title":"Mol Biol Evol"},{"key":"8125_CR30","first-page":"737","volume":"48","author":"F Saat","year":"2017","unstructured":"Saat F, Nyunt MH, Abdullah NR et al (2017) Genetic diversity of Plasmodium vivax Duffy binding protein (PvDBP) gene in Sabah, Malaysia. Southeast Asian J Trop Med Public Health 48:737\u2013748","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"8125_CR31","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1186\/s12936-022-04167-w","volume":"21","author":"P Sai-Ngam","year":"2022","unstructured":"Sai-Ngam P, Pidtana K, Suida P et al (2022) Case series of three malaria patients from Thailand infected with the simian parasite. Plasmodium Cynomolgi Malar J 21:142. https:\/\/doi.org\/10.1186\/s12936-022-04167-w","journal-title":"Plasmodium Cynomolgi Malar J"},{"key":"8125_CR32","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/j.meegid.2016.03.009","volume":"40","author":"PL Sutton","year":"2016","unstructured":"Sutton PL, Luo Z, Divis PC et al (2016) Characterizing the genetic diversity of the monkey malaria parasite Plasmodium cynomolgi. Infect Genet Evol 40:243\u2013252. https:\/\/doi.org\/10.1016\/j.meegid.2016.03.009","journal-title":"Infect Genet Evol"},{"key":"8125_CR33","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1186\/1475-2875-13-68","volume":"13","author":"TH Ta","year":"2014","unstructured":"Ta TH, Hisam S, Lanza M et al (2014) First case of a naturally acquired human infection with Plasmodium cynomolgi. Malar J 13:68. https:\/\/doi.org\/10.1186\/1475-2875-13-68","journal-title":"Malar J"},{"key":"8125_CR34","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1038\/ng.2375","volume":"44","author":"S Tachibana","year":"2012","unstructured":"Tachibana S, Sullivan SA, Kawai S et al (2012) Plasmodium cynomolgi genome sequences provide insight into Plasmodium vivax and the monkey malaria clade. Nat Genet 44:1051\u20131055. https:\/\/doi.org\/10.1038\/ng.2375","journal-title":"Nat Genet"},{"key":"8125_CR35","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1093\/genetics\/123.3.585","volume":"123","author":"F Tajima","year":"1989","unstructured":"Tajima F (1989) Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics 123:585\u2013595. https:\/\/doi.org\/10.1093\/genetics\/123.3.585","journal-title":"Genetics"},{"key":"8125_CR36","doi-asserted-by":"publisher","first-page":"14","DOI":"10.2307\/3276382","volume":"52","author":"M Warren","year":"1966","unstructured":"Warren M, Skinner J, Guinn E (1966) Biology of the simian malarias of Southeast Asia. I. Host cell preferences of young trophozoites of four species of Plasmodium. J Parasitol 52:14\u201316","journal-title":"J Parasitol"},{"key":"8125_CR37","doi-asserted-by":"publisher","first-page":"2187","DOI":"10.3201\/eid2708.204502","volume":"27","author":"NJ Yap","year":"2021","unstructured":"Yap NJ, Hossain H, Nada-Raja T et al (2021) Natural human infections with Plasmodium cynomolgi, P. inui, and 4 other simian malaria parasites. Malaysia Emerg Infect Dis 27:2187\u20132191. https:\/\/doi.org\/10.3201\/eid2708.204502","journal-title":"Malaysia Emerg Infect Dis"},{"issue":"29","key":"8125_CR38","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1051\/parasite\/2022032","volume":"29","author":"NM Yusuf","year":"2022","unstructured":"Yusuf NM, Zulkefli J, Jiram AI et al (2022) Plasmodium spp. in macaques, Macaca fascicularis, in Malaysia, and their potential role in zoonotic malaria transmission. Parasite 29(29):32. https:\/\/doi.org\/10.1051\/parasite\/2022032","journal-title":"Parasite"}],"container-title":["Parasitology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-024-08125-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00436-024-08125-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00436-024-08125-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,5]],"date-time":"2024-02-05T11:11:34Z","timestamp":1707131494000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00436-024-08125-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["8125"],"URL":"https:\/\/doi.org\/10.1007\/s00436-024-08125-0","relation":{},"ISSN":["0932-0113","1432-1955"],"issn-type":[{"value":"0932-0113","type":"print"},{"value":"1432-1955","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"9 November 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 January 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 January 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the University of Malaya Institutional Animal Care and Use Committee (M\/06122019\/25022019\u201301\/R), and the macaque blood sampling protocol was approved by UC Davis IACUC (Protocol No. 16048). All methods were performed in accordance with relevant guidelines and regulations.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"105"}}