{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T14:18:17Z","timestamp":1772720297472,"version":"3.50.1"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2018,3,27]],"date-time":"2018-03-27T00:00:00Z","timestamp":1522108800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Hirszfeld Institute of Immunology and Experimental Therapy","award":["grants No. 14\/2016 and 14\/2017"],"award-info":[{"award-number":["grants No. 14\/2016 and 14\/2017"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Genet Genomics"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1007\/s00438-018-1435-4","type":"journal-article","created":{"date-parts":[[2018,3,27]],"date-time":"2018-03-27T13:54:25Z","timestamp":1522158865000},"page":"957-966","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["HLA-C*06:02-independent, gender-related association of PSORS1C3 and PSORS1C1\/CDSN single-nucleotide polymorphisms with risk and severity of psoriasis"],"prefix":"10.1007","volume":"293","author":[{"given":"Andrzej","family":"Wi\u015bniewski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0141ukasz","family":"Matusiak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aneta","family":"Szczerkowska-Dobosz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Izabela","family":"Nowak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"Ku\u015bnierczyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,3,27]]},"reference":[{"key":"1435_CR1","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1172\/JCI84424","volume":"127","author":"BD Adams","year":"2017","unstructured":"Adams BD, Parsons C, Walker L, Zhang WC, Slack FJ (2017) Targeting noncoding RNAs in disease. J Clin Invest 127:761\u2013771","journal-title":"J Clin Invest"},{"key":"1435_CR2","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1038\/labinvest.3780309","volume":"81","author":"M Allen","year":"2001","unstructured":"Allen M, Ishida-Yamamoto A, McGrath J, Davison S, Iizuka H, Simon M, Guerrin M, Hayday A, Vaughan R, Serre G, Trembath R, Barker J (2001) Corneodesmosin expression in psoriasis vulgaris differs from normal skin and other inflammatory skin disorders. Lab Invest 81:969\u2013976","journal-title":"Lab Invest"},{"key":"1435_CR3","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1111\/j.0022-202X.2004.23511.x","volume":"124","author":"MH Allen","year":"2005","unstructured":"Allen MH, Ameen H, Veal C, Evans J, Ramrakha-Jones VS, Marsland AM, Burden AD, Griffiths CE, Trembath RC, Barker JN (2005) The major psoriasis susceptibility locus PSORS1 is not a risk factor for late-onset psoriasis. J Invest Dermatol 124:103\u2013106","journal-title":"J Invest Dermatol"},{"key":"1435_CR4","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1111\/j.1365-2230.2005.01789.x","volume":"30","author":"M Ameen","year":"2005","unstructured":"Ameen M, Allen MH, Fisher SA, Lewis CM, Cuthbert A, Kondeatis E, Vaughan RW, Murakami H, Nakagawa H, Barker JN (2005) Corneodesmosin (CDSN) gene association with psoriasis vulgaris in Caucasian but not in Japanese populations. Clin Exp Dermatol 30:414\u2013418","journal-title":"Clin Exp Dermatol"},{"key":"1435_CR5","doi-asserted-by":"publisher","first-page":"2203","DOI":"10.1084\/jem.20151093","volume":"212","author":"A Arakawa","year":"2015","unstructured":"Arakawa A, Siewert K, St\u00f6hr J, Besgen P, Kim SM, R\u00fchl G, Nickel J, Vollmer S, Thomas P, Krebs S et al (2015) Melanocyte antigen triggers autoimmunity in human psoriasis. J Exp Med 212:2203\u20132212","journal-title":"J Exp Med"},{"key":"1435_CR6","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1016\/S0140-6736(14)61909-7","volume":"386","author":"W-H Boehncke","year":"2015","unstructured":"Boehncke W-H, Sch\u00f6n MP (2015) Psoriasis Lancet 386:983\u2013994","journal-title":"Psoriasis Lancet"},{"key":"1435_CR7","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18122526","author":"F Capon","year":"2017","unstructured":"Capon F (2017) The genetic basis of psoriasis. Int J Mol Sci 25:18(12). https:\/\/doi.org\/10.3390\/ijms18122526","journal-title":"Int J Mol Sci"},{"key":"1435_CR8","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1046\/j.1523-1747.2002.01749.x","volume":"118","author":"F Capon","year":"2002","unstructured":"Capon F, Munro M, Barker J, Trembath R (2002) Searching for the major histocompatibility complex psoriasis susceptibility gene. J Invest Dermatol 118:745\u2013751","journal-title":"J Invest Dermatol"},{"key":"1435_CR9","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1136\/jmg.40.6.447","volume":"40","author":"F Capon","year":"2003","unstructured":"Capon F, Toal IK, Evans JC, Allen MH, Patel S, Tillman D, Burden D, Barker JN, Trembath RC (2003) Haplotype analysis of distantly related populations implicates corneodesmosin in psoriasis susceptibility. J Med Genet 40:447\u2013452","journal-title":"J Med Genet"},{"key":"1435_CR10","doi-asserted-by":"publisher","first-page":"2361","DOI":"10.1093\/hmg\/ddh273","volume":"13","author":"F Capon","year":"2004","unstructured":"Capon F, Allen MH, Ameen M, Burden AD, Tillman D, Barker JN, Trembath RC (2004) A synonymous SNP of the corneodesmosin gene leads to increased mRNA stability and demonstrates association with psoriasis across diverse ethnic groups. Hum Mol Genet 13:2361\u20132368","journal-title":"Hum Mol Genet"},{"key":"1435_CR11","doi-asserted-by":"crossref","unstructured":"Chang YT, Liu HN, Shiao YM, Lin MW, Lee DD, Liu MT, Wang WJ, Wu S, Lai CY, Tsai SF (2005) A study of PSORS1C1 gene polymorphisms in Chinese patients with psoriasis. Br J Dermatol 153:90\u201396","DOI":"10.1111\/j.1365-2133.2005.06570.x"},{"key":"1435_CR12","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1111\/j.1365-2133.2006.07420.x","volume":"155","author":"YT Chang","year":"2006","unstructured":"Chang YT, Chou CT, Shiao YM, Lin MW, Yu CW, Chen CC, Huang CH, Lee DD, Liu HN, Wang WJ, Tsai SF (2006) Psoriasis vulgaris in Chinese individuals is associated with PSORS1C3 and CDSN genes. Br J Dermatol 155:663\u2013669","journal-title":"Br J Dermatol"},{"issue":"8","key":"1435_CR13","doi-asserted-by":"publisher","first-page":"e71690","DOI":"10.1371\/journal.pone.0071690","volume":"8","author":"A Clop","year":"2013","unstructured":"Clop A, Bertoni A, Spain SL, Simpson MA, Pullabhatla V, Tonda R, Hundhausen C, Di Meglio P, De Jong P, Hayday AC et al (2013) An in-depth characterization of the major psoriasis susceptibility locus identifies candidate susceptibility alleles within an HLA-C enhancer element. PLoS One 8(8):e71690","journal-title":"PLoS One"},{"issue":"56","key":"1435_CR14","doi-asserted-by":"crossref","first-page":"95066","DOI":"10.18632\/oncotarget.11144","volume":"8","author":"Q Cui","year":"2016","unstructured":"Cui Q, Feng FT, Xu M, Liu WS, Yao YY, Xie SH, Li XZ, Ye ZL, Feng QS, Chen LZ, Bei JX et al (2016) Nasopharyngeal carcinoma risk prediction via salivary detection of host and Epstein-Barr virus genetic variants. Oncotarget 8(56):95066\u201395074","journal-title":"Oncotarget"},{"issue":"8","key":"1435_CR15","doi-asserted-by":"publisher","first-page":"a015354","DOI":"10.1101\/cshperspect.a015354","volume":"4","author":"P Meglio Di","year":"2014","unstructured":"Di Meglio P, Villanova F, Nestle FO (2014) Psoriasis. Cold Spring Harb Perspect Med 4(8):a015354","journal-title":"Cold Spring Harb Perspect Med"},{"key":"1435_CR16","unstructured":"Ensembl Nov. (2017). https:\/\/www.ensembl.org"},{"issue":"8","key":"1435_CR17","doi-asserted-by":"publisher","first-page":"e1000606","DOI":"10.1371\/journal.pgen.1000606","volume":"5","author":"BJ Feng","year":"2009","unstructured":"Feng BJ, Sun LD, Soltani-Arabshahi R, Bowcock AM, Nair RP, Stuart P, Elder JT, Schrodi SJ, Begovich AB, Abecasis GR et al (2009) Multiple Loci within the major histocompatibility complex confer risk of psoriasis. PLoS Genet 5(8):e1000606","journal-title":"PLoS Genet"},{"key":"1435_CR18","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1046\/j.0022-202x.2001.01656.x","volume":"118","author":"JE Gudj\u00f3nsson","year":"2002","unstructured":"Gudj\u00f3nsson JE, K\u00e1rason A, Antonsd\u00f3ttir AA, R\u00fanarsd\u00f3ttir EH, Gulcher JR, Stef\u00e1nsson K, Valdimarsson H (2002) HLA-Cw6-positive and HLA-Cw6-negative patients with Psoriasis vulgaris have distinct clinical features. J Invest Dermatol 118:362\u2013365","journal-title":"J Invest Dermatol"},{"key":"1435_CR19","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1007\/s40257-017-0274-0","volume":"18","author":"D H\u00e4gg","year":"2017","unstructured":"H\u00e4gg D, Sundstr\u00f6m A, Eriksson M, Schmitt-Egenolf M (2017) Severity of psoriasis differs between men and women: a study of the clinical outcome measure psoriasis area and severity index (PASI) in 5438 Swedish register patients. Am J Clin Dermatol 18:583\u2013590","journal-title":"Am J Clin Dermatol"},{"key":"1435_CR20","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.jaut.2015.07.008","volume":"64","author":"JL Harden","year":"2015","unstructured":"Harden JL, Krueger JG, Bowcock AM (2015) The immunogenetics of Psoriasis: A comprehensive review. J Autoimmun 64:66\u201373","journal-title":"J Autoimmun"},{"key":"1435_CR21","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1016\/S0190-9622(85)70188-0","volume":"13","author":"T Henseler","year":"1985","unstructured":"Henseler T, Christophers E (1985) Psoriasis of early and late onset: characterization of two types of psoriasis vulgaris. J Am Acad Dermatol 13:450\u2013456","journal-title":"J Am Acad Dermatol"},{"key":"1435_CR22","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1080\/00015550410023527","volume":"85","author":"SJ Holm","year":"2005","unstructured":"Holm SJ, S\u00e1nchez F, Carl\u00e9n LM, Mallbris L, Stahle M, O\u2019Brien KP (2005) HLA-Cw*0602 associates more strongly to psoriasis in the Swedish population than variants of the novel 6p21.3 gene PSORS1C3. Acta Derm Venereol 85:2\u20138","journal-title":"Acta Derm Venereol"},{"key":"1435_CR23","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1038\/sj.jid.5700179","volume":"126","author":"U H\u00fcffmeier","year":"2006","unstructured":"H\u00fcffmeier U, Reis A, Steffens M, Lascorz J, B\u00f6hm B, Lohmann J, Wendler J, Traupe H, K\u00fcster W, Wienker TF, Burkhardt H (2006) Male restricted genetic association of variant R620W in PTPN22 with psoriatic arthritis. J Invest Dermatol 126:932\u2013935","journal-title":"J Invest Dermatol"},{"key":"1435_CR24","doi-asserted-by":"crossref","unstructured":"Jenisch S, Koch S, Henseler T, Nair RP, Elder JT, Watts CE, Westphal E, Voorhees JJ, Christophers E, Kr\u00f6nke M (1999) Corneodesmosin gene polymorphism demonstrates strong linkage disequilibrium with HLA and association with psoriasis vulgaris. Tissue Antigens 54:439\u2013449","DOI":"10.1034\/j.1399-0039.1999.540501.x"},{"key":"1435_CR25","doi-asserted-by":"publisher","unstructured":"Jonca N, Leclerc EA, Caubet C, Simon M, Guerrin M, Serre G (2011) Corneodesmosomes and corneodesmosin: from the stratum corneum cohesion to the pathophysiology of genodermatoses. Eur J Dermatol 21 Suppl 2:35\u201342. https:\/\/doi.org\/10.1684\/ejd.2011.1264","DOI":"10.1684\/ejd.2011.1264"},{"key":"1435_CR26","doi-asserted-by":"publisher","first-page":"1833","DOI":"10.1038\/jid.2012.69","volume":"132","author":"OY Lai","year":"2012","unstructured":"Lai OY, Chen H, Michaud HA, Hayashi G, Kuebler PJ, Hultman GK, Ariza ME, Williams MV, Batista MD, Nixon DF, Foerster J, Bowcock AM, Liao W (2012) Protective effect of human endogenous retrovirus K dUTPase variants on psoriasis susceptibility. J Invest Dermatol 132:1833\u20131840","journal-title":"J Invest Dermatol"},{"key":"1435_CR27","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/S0165-2478(02)00212-2","volume":"85","author":"W \u0141uszczek","year":"2003","unstructured":"\u0141uszczek W, Kubicka W, Cislo M, Nockowski P, Ma\u0144czak M, Woszczek G, Baran E, Ku\u015bnierczyk P (2003) Strong association of HLA-Cw6 allele with juvenile psoriasis in Polish patients. Immunol Lett 85:59\u201364","journal-title":"Immunol Lett"},{"key":"1435_CR28","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1038\/jid.2012.280","volume":"133","author":"J Lysell","year":"2013","unstructured":"Lysell J, Padyukov L, Kockum I, Nikamo P, Stahle M (2013) Genetic association with ERAP1 in psoriasis is confined to disease onset after puberty and not dependent on HLA-C*06. J Invest Dermatol 133:411\u2013417","journal-title":"J Invest Dermatol"},{"key":"1435_CR29","doi-asserted-by":"publisher","first-page":"17203","DOI":"10.1074\/jbc.M117.806976","volume":"292","author":"JI Mobbs","year":"2017","unstructured":"Mobbs JI, Illing PT, Dudek NL, Brooks AG, Baker DG, Purcell AW, Rossjohn J, Vivian JP (2017) The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule. J Biol Chem 292:17203\u201317215","journal-title":"J Biol Chem"},{"key":"1435_CR30","doi-asserted-by":"publisher","first-page":"1833","DOI":"10.1086\/302932","volume":"66","author":"RP Nair","year":"2000","unstructured":"Nair RP, Stuart P, Henseler T, Jenisch S, Chia NV, Westphal E, Schork NJ, Kim J, Lim HW, Christophers E, Voorhees JJ, Elder JT (2000) Localization of psoriasis-susceptibility locus PSORS1 to a 60-kb interval telomeric to HLA-C. Am J Hum Genet 66:1833\u20131844 (Erratum in: Am J Hum Genet 2002 70:1074)","journal-title":"Am J Hum Genet"},{"key":"1435_CR31","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1086\/503821","volume":"78","author":"RP Nair","year":"2006","unstructured":"Nair RP, Stuart PE, Nistor I, Hiremagalore R, Chia NV, Jenisch S, Weichenthal M, Abecasis GR, Lim HW, Christophers E, Voorhees JJ, Elder JT (2006) Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene. Am J Hum Genet 78:827\u2013851","journal-title":"Am J Hum Genet"},{"key":"1435_CR32","unstructured":"NCBI dbSNP, Nov (2017) https:\/\/www.ncbi.nlm.nih.gov\/snp\/"},{"key":"1435_CR33","doi-asserted-by":"crossref","unstructured":"Orr\u00f9 S, Giuressi E, Carcassi C, Casula M, Contu L (2005) Mapping of the major psoriasis-susceptibility locus (PSORS1) in a 70-Kb interval around the corneodesmosin gene (CDSN). Am J Hum Genet 76:164\u2013171","DOI":"10.1086\/426948"},{"key":"1435_CR34","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1086\/519795","volume":"81","author":"S Purcell","year":"2007","unstructured":"Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, Maller J, Sklar P, de Bakker PI, Daly MJ, Sham PC (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81:559\u2013575","journal-title":"Am J Hum Genet"},{"key":"1435_CR35","doi-asserted-by":"publisher","first-page":"482691","DOI":"10.1155\/2013\/482691","volume":"2013","author":"R Queiro","year":"2013","unstructured":"Queiro R, Tej\u00f3n P, Coto P, Alonso S, Alperi M, Sarasqueta C, Gonz\u00e1lez S, Mart\u00ednez-Borra J, L\u00f3pez-Larrea C, Ballina J (2013) Clinical differences between men and women with psoriatic arthritis: relevance of the analysis of genes and polymorphisms in the major histocompatibility complex region and of the age at onset of psoriasis. Clin Dev Immunol 2013:482691. https:\/\/doi.org\/10.1155\/2013\/482691","journal-title":"Clin Dev Immunol"},{"key":"1435_CR36","doi-asserted-by":"publisher","first-page":"1178","DOI":"10.1093\/rheumatology\/ket363","volume":"53","author":"R Queiro","year":"2014","unstructured":"Queiro R, Tej\u00f3n P, Alonso S, Coto P (2014) Age at disease onset: a key factor for understanding psoriatic disease. Rheumatology (Oxford) 53:1178\u20131185","journal-title":"Rheumatology (Oxford)"},{"key":"1435_CR37","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1159\/000086437","volume":"211","author":"R Sakai","year":"2005","unstructured":"Sakai R, Matsui S, Fukushima M, Yasuda H, Miyauchi H, Miyachi Y (2005) Prognostic factor analysis for plaque psoriasis. Dermatology 211:103\u2013106","journal-title":"Dermatology"},{"key":"1435_CR38","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1159\/000083509","volume":"210","author":"J Schmitt","year":"2005","unstructured":"Schmitt J, Wozel G (2005) The psoriasis area and severity index is the adequate criterion to define severity in chronic plaque-type psoriasis. Dermatology 210:194","journal-title":"Dermatology"},{"key":"1435_CR39","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1038\/ng.694","volume":"42","author":"A Strange","year":"2010","unstructured":"Strange A, Capon F, Spencer CC, Knight J, Weale ME, Allen MH, Barton A, Band G, Bellenguez C, Bergboer JG et al (2010) Genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet 42:985\u2013990","journal-title":"Nat Genet"},{"key":"1435_CR40","doi-asserted-by":"publisher","first-page":"1135","DOI":"10.1093\/hmg\/8.6.1135","volume":"8","author":"R Tazi Ahnini","year":"1999","unstructured":"Tazi Ahnini R, Camp NJ, Cork MJ, Mee JB, Keohane SG, Duff GW, di Giovine FS (1999) Novel genetic association between the corneodesmosin (MHC S) gene and susceptibility to psoriasis. Hum Mol Genet 8:1135\u20131140","journal-title":"Hum Mol Genet"},{"key":"1435_CR41","doi-asserted-by":"publisher","first-page":"e49920","DOI":"10.1371\/journal.pone.0049920","volume":"7","author":"MH Tervaniemi","year":"2012","unstructured":"Tervaniemi MH, Siitonen HA, S\u00f6derh\u00e4ll C, Minhas G, Vuola J, Tiala I, Sormunen R, Samuelsson L, Suomela S, Kere J, Elomaa O (2012) Centrosomal localization of the psoriasis candidate gene product, CCHCR1, supports a role in cytoskeletal organization. PLoS One 7:e49920. https:\/\/doi.org\/10.1371\/journal.pone.0049920","journal-title":"PLoS One"},{"key":"1435_CR42","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1093\/hmg\/6.5.813","volume":"6","author":"RC Trembath","year":"1997","unstructured":"Trembath RC, Clough RL, Rosbotham JL, Jones AB, Camp RD, Frodsham A, Browne J, Barber R, Terwilliger J, Lathrop GM, Barker JN (1997) Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis. Hum Mol Genet 6:813\u2013820","journal-title":"Hum Mol Genet"},{"key":"1435_CR43","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1086\/342289","volume":"71","author":"CD Veal","year":"2002","unstructured":"Veal CD, Veal CD, Capon F, Allen MH, Heath EK, Evans JC, Jones A, Patel S, Burden D, Tillman D, Barker JN, Trembath RC (2002) Family-based analysis using a dense single-nucleotide polymorphism-based map defines genetic variation at PSORS1, the major psoriasis-susceptibility locus. Am J Hum Genet 71:554\u2013564","journal-title":"Am J Hum Genet"},{"key":"1435_CR44","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.3892\/etm.2016.3066","volume":"11","author":"A Villarreal-Mart\u00ednez","year":"2016","unstructured":"Villarreal-Mart\u00ednez A, Gallardo-Blanco H, Cerda-Flores R, Torres-Mu\u00f1oz I, G\u00f3mez-Flores M, Salas-Alan\u00eds J, Ocampo-Candiani J, Mart\u00ednez-Garza L (2016) Candidate gene polymorphisms and risk of psoriasis: a pilot study. Exp Ther Med 11:1217\u20131222","journal-title":"Exp Ther Med"},{"issue":"2","key":"1435_CR45","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.humimm.2017.11.010","volume":"79","author":"A Wi\u015bniewski","year":"2018","unstructured":"Wi\u015bniewski A, Matusiak \u0141, Szczerkowska-Dobosz A, Nowak I, \u0141uszczek W, Ku\u015bnierczyk P (2018) The association of ERAP1 and ERAP2 single nucleotide polymorphisms and their haplotypes with psoriasis vulgaris is dependent on the presence or absence of the HLA-C*06:02 allele and age at disease onset. Hum Immunol 79(2):109\u2013116","journal-title":"Hum Immunol"}],"container-title":["Molecular Genetics and Genomics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00438-018-1435-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00438-018-1435-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00438-018-1435-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T07:18:20Z","timestamp":1604042300000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00438-018-1435-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,27]]},"references-count":45,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["1435"],"URL":"https:\/\/doi.org\/10.1007\/s00438-018-1435-4","relation":{},"ISSN":["1617-4615","1617-4623"],"issn-type":[{"value":"1617-4615","type":"print"},{"value":"1617-4623","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,27]]},"assertion":[{"value":"29 December 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 March 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 March 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Andrzej Wi\u015bniewski declares that he has no conflict of interest. \u0141ukasz Matusiak declares that he has no conflict of interest. Aneta Szczerkowska-Dobosz declares that she has no conflict of interest. Izabela Nowak declares that she has no conflict of interest. Piotr Ku\u015bnierczyk declares that he has no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}