{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:51:10Z","timestamp":1792068670340,"version":"4.4.0"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Youth project of Science and Technology Department of Shanxi Province","award":["Grant No. 202203021212105"],"award-info":[{"award-number":["Grant No. 202203021212105"]}]},{"name":"Youth project of Science and Technology Department of Shanxi Province","award":["Grant No. 202203021212105"],"award-info":[{"award-number":["Grant No. 202203021212105"]}]},{"name":"Youth project of Science and Technology Department of Shanxi Province","award":["Grant No. 202203021212105"],"award-info":[{"award-number":["Grant No. 202203021212105"]}]},{"name":"the Shanxi Bethune Hospital talent project","award":["Grant No. 2022RC05"],"award-info":[{"award-number":["Grant No. 2022RC05"]}]},{"name":"the Shanxi Bethune Hospital talent project","award":["Grant No. 2022RC05"],"award-info":[{"award-number":["Grant No. 2022RC05"]}]},{"name":"the Shanxi Bethune Hospital talent project","award":["Grant No. 2022RC05"],"award-info":[{"award-number":["Grant No. 2022RC05"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Genet Genomics"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1007\/s00438-026-02531-y","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:15:41Z","timestamp":1792066541000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["USP11 inhibits cuproptosis in non-small cell lung cancer by deubiquitinating IGF2BP2 to enhance the stability of m6A-modified ATOX1 mRNA"],"prefix":"10.1007","volume":"301","author":[{"given":"Lin","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiansheng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongxia","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,15]]},"reference":[{"issue":"1","key":"2531_CR1","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/s12943-022-01500-4","volume":"21","author":"Y An","year":"2022","unstructured":"An Y, Duan H (2022) The role of m6A RNA methylation in cancer metabolism. Mol Cancer 21(1):14. https:\/\/doi.org\/10.1186\/s12943-022-01500-4","journal-title":"Mol Cancer"},{"issue":"3","key":"2531_CR2","doi-asserted-by":"publisher","first-page":"229","DOI":"10.3322\/caac.21834","volume":"74","author":"F Bray","year":"2024","unstructured":"Bray F, Laversanne M et al (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 74(3):229\u2013263. https:\/\/doi.org\/10.3322\/caac.21834","journal-title":"CA Cancer J Clin"},{"issue":"1","key":"2531_CR3","doi-asserted-by":"publisher","first-page":"269","DOI":"10.3892\/or.2013.2436","volume":"30","author":"H Cai","year":"2013","unstructured":"Cai H, Peng F (2013) Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells. Oncol Rep 30(1):269\u2013275. https:\/\/doi.org\/10.3892\/or.2013.2436","journal-title":"Oncol Rep"},{"issue":"1","key":"2531_CR5","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1038\/s41392-022-01229-y","volume":"7","author":"L Chen","year":"2022","unstructured":"Chen L, Min J et al (2022) Copper homeostasis and cuproptosis in health and disease. Signal Transduct Target Ther 7(1):378. https:\/\/doi.org\/10.1038\/s41392-022-01229-y","journal-title":"Signal Transduct Target Ther"},{"key":"2531_CR4","doi-asserted-by":"publisher","unstructured":"Chen J, Li C et al (2025) Identify new pseudogene RPL7P1-oriented network as a drug target against infections pre-existing diabetes. Integr Biol. https:\/\/doi.org\/10.1093\/intbio\/zyaf015","DOI":"10.1093\/intbio\/zyaf015"},{"issue":"3","key":"2531_CR6","doi-asserted-by":"publisher","first-page":"647","DOI":"10.17305\/bb.2023.9931","volume":"24","author":"R Deng","year":"2024","unstructured":"Deng R, Zhu L et al (2024a) Cuproptosis-related gene LIPT1 as a prognostic indicator in non-small cell lung cancer: functional involvement and regulation of ATOX1 expression. Biomol Biomed 24(3):647\u2013658. https:\/\/doi.org\/10.17305\/bb.2023.9931","journal-title":"Biomol Biomed"},{"issue":"1","key":"2531_CR7","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1007\/s13402-023-00866-x","volume":"47","author":"T Deng","year":"2024","unstructured":"Deng T, Xie L et al (2024b) ATM-Mediated translocation of RanBPM regulates DNA damage response by stabilizing p21 in non-small cell lung cancer cells. Cell Oncol 47(1):245\u2013258. https:\/\/doi.org\/10.1007\/s13402-023-00866-x","journal-title":"Cell Oncol (Dordr)"},{"issue":"40","key":"2531_CR8","doi-asserted-by":"publisher","first-page":"2971","DOI":"10.1038\/s41388-024-03139-5","volume":"43","author":"K Du","year":"2024","unstructured":"Du K, Luo Y et al (2024) m(6)A modification of lipoyltransferase 1 inhibits bladder cancer progression by activating cuproptosis. Oncogene 43(40):2971\u20132985. https:\/\/doi.org\/10.1038\/s41388-024-03139-5","journal-title":"Oncogene"},{"issue":"12","key":"2531_CR10","doi-asserted-by":"publisher","first-page":"3527","DOI":"10.1002\/1878-0261.13079","volume":"15","author":"W Gao","year":"2021","unstructured":"Gao W, Huang Z et al (2021) Elesclomol induces copper-dependent ferroptosis in colorectal cancer cells via degradation of ATP7A. Mol Oncol 15(12):3527\u20133544. https:\/\/doi.org\/10.1002\/1878-0261.13079","journal-title":"Mol Oncol"},{"issue":"1","key":"2531_CR11","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1186\/s12943-019-1109-9","volume":"18","author":"L He","year":"2019","unstructured":"He L, Li H et al (2019) Functions of N6-methyladenosine and its role in cancer. Mol Cancer 18(1):176. https:\/\/doi.org\/10.1186\/s12943-019-1109-9","journal-title":"Mol Cancer"},{"issue":"2","key":"2531_CR13","first-page":"480","volume":"13","author":"YY Huang","year":"2021","unstructured":"Huang YY, Zhang CM et al (2021) USP11 facilitates colorectal cancer proliferation and metastasis by regulating IGF2BP3 stability. Am J Transl Res 13(2):480\u2013496","journal-title":"Am J Transl Res"},{"key":"2531_CR12","doi-asserted-by":"publisher","first-page":"106942","DOI":"10.1016\/j.ejps.2024.106942","volume":"204","author":"P Huang","year":"2025","unstructured":"Huang P, Wu G et al (2025) Copper-coordinated nanomedicine for the concurrent treatment of lung cancer through the induction of cuproptosis and apoptosis. Eur J Pharm Sci 204:106942. https:\/\/doi.org\/10.1016\/j.ejps.2024.106942","journal-title":"Eur J Pharm Sci"},{"issue":"12","key":"2531_CR14","doi-asserted-by":"publisher","first-page":"1659","DOI":"10.1261\/rna.065649.118","volume":"24","author":"M Jia","year":"2018","unstructured":"Jia M, Gut H et al (2018) Structural basis of IMP3 RRM12 recognition of RNA. RNA 24(12):1659\u20131666. https:\/\/doi.org\/10.1261\/rna.065649.118","journal-title":"RNA"},{"issue":"6","key":"2531_CR15","doi-asserted-by":"publisher","first-page":"1159","DOI":"10.2174\/1871520621666210726132543","volume":"22","author":"ZY Lee","year":"2022","unstructured":"Lee ZY, Leong CH et al (2022) Induction of apoptosis and autophagy by ternary copper complex towards breast cancer cells. Anticancer Agents Med Chem 22(6):1159\u20131170. https:\/\/doi.org\/10.2174\/1871520621666210726132543","journal-title":"Anticancer Agents Med Chem"},{"issue":"1","key":"2531_CR16","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1038\/s41467-020-20527-z","volume":"12","author":"B Li","year":"2021","unstructured":"Li B, Zhu L et al (2021) circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity. Nat Commun 12(1):295. https:\/\/doi.org\/10.1038\/s41467-020-20527-z","journal-title":"Nat Commun"},{"key":"2531_CR17","doi-asserted-by":"publisher","unstructured":"Li P, Sun Q et al (2024) Combination of the cuproptosis inducer disulfiram and anti\u2013PD\u2013L1 abolishes NSCLC resistance by ATP7B to regulate the HIF\u20131 signaling pathway. Int J Mol Med. https:\/\/doi.org\/10.3892\/ijmm.2023.5343","DOI":"10.3892\/ijmm.2023.5343"},{"issue":"1","key":"2531_CR18","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1038\/s41420-022-01083-5","volume":"8","author":"Y Liao","year":"2022","unstructured":"Liao Y, Zhou D et al (2022) Ubiquitin specific peptidase 11 as a novel therapeutic target for cancer management. Cell Death Discov 8(1):292. https:\/\/doi.org\/10.1038\/s41420-022-01083-5","journal-title":"Cell Death Discov"},{"issue":"13","key":"2531_CR19","doi-asserted-by":"publisher","first-page":"2187","DOI":"10.1158\/0008-5472.CAN-22-3059","volume":"83","author":"Z Lin","year":"2023","unstructured":"Lin Z, Li J et al (2023) Metabolic reprogramming driven by IGF2BP3 promotes acquired resistance to EGFR inhibitors in non-small cell lung cancer. Cancer Res 83(13):2187\u20132207. https:\/\/doi.org\/10.1158\/0008-5472.CAN-22-3059","journal-title":"Cancer Res"},{"issue":"1","key":"2531_CR20","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1186\/s12943-024-02046-3","volume":"23","author":"F Liu","year":"2024","unstructured":"Liu F, Chen J et al (2024) Ubiquitination and deubiquitination in cancer: from mechanisms to novel therapeutic approaches. Mol Cancer 23(1):148. https:\/\/doi.org\/10.1186\/s12943-024-02046-3","journal-title":"Mol Cancer"},{"issue":"1","key":"2531_CR21","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1186\/s12935-025-03864-1","volume":"25","author":"C Luo","year":"2025","unstructured":"Luo C, Wu X et al (2025a) Cuproptosis: a novel therapeutic mechanism in lung cancer. Cancer Cell Int 25(1):231. https:\/\/doi.org\/10.1186\/s12935-025-03864-1","journal-title":"Cancer Cell Int"},{"key":"2531_CR22","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.freeradbiomed.2025.01.029","volume":"229","author":"X Luo","year":"2025","unstructured":"Luo X, Linghu M et al (2025b) Merestinib inhibits cuproptosis by targeting NRF2 to alleviate acute liver injury. Free Radic Biol Med 229:68\u201381. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2025.01.029","journal-title":"Free Radic Biol Med"},{"issue":"9","key":"2531_CR23","doi-asserted-by":"publisher","first-page":"1706","DOI":"10.1038\/s41388-021-01660-5","volume":"40","author":"C Meng","year":"2021","unstructured":"Meng C, Zhan J et al (2021) The deubiquitinase USP11 regulates cell proliferation and ferroptotic cell death via stabilization of NRF2 USP11 deubiquitinates and stabilizes NRF2. Oncogene 40(9):1706\u20131720. https:\/\/doi.org\/10.1038\/s41388-021-01660-5","journal-title":"Oncogene"},{"issue":"1","key":"2531_CR24","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.tig.2022.10.004","volume":"39","author":"I Orsolic","year":"2023","unstructured":"Orsolic I, Carrier A et al (2023) Genetic and epigenetic defects of the RNA modification machinery in cancer. Trends Genet 39(1):74\u201388. https:\/\/doi.org\/10.1016\/j.tig.2022.10.004","journal-title":"Trends Genet"},{"issue":"Pt 1","key":"2531_CR25","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.semcancer.2017.11.019","volume":"52","author":"L Osmani","year":"2018","unstructured":"Osmani L, Askin F et al (2018) Current WHO guidelines and the critical role of immunohistochemical markers in the subclassification of non-small cell lung carcinoma (NSCLC): Moving from targeted therapy to immunotherapy. Semin Cancer Biol 52(Pt 1):103\u2013109. https:\/\/doi.org\/10.1016\/j.semcancer.2017.11.019","journal-title":"Semin Cancer Biol"},{"key":"2531_CR26","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.canlet.2021.05.015","volume":"514","author":"L Qiao","year":"2021","unstructured":"Qiao L, Zhang Q et al (2021) The E2F1\/USP11 positive feedback loop promotes hepatocellular carcinoma metastasis and inhibits autophagy by activating ERK\/mTOR pathway. Cancer Lett 514:63\u201378. https:\/\/doi.org\/10.1016\/j.canlet.2021.05.015","journal-title":"Cancer Lett"},{"issue":"1","key":"2531_CR27","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1186\/s40360-024-00784-0","volume":"25","author":"X Qin","year":"2024","unstructured":"Qin X, Wang P et al (2024) Curcumin suppresses copper accumulation in non-small cell lung cancer by binding ATOX1. BMC Pharmacol Toxicol 25(1):54. https:\/\/doi.org\/10.1186\/s40360-024-00784-0","journal-title":"BMC Pharmacol Toxicol"},{"issue":"2","key":"2531_CR28","doi-asserted-by":"publisher","first-page":"118893","DOI":"10.1016\/j.bbamcr.2020.118893","volume":"1868","author":"VC Shanbhag","year":"2021","unstructured":"Shanbhag VC, Gudekar N et al (2021) Copper metabolism as a unique vulnerability in cancer. Biochim Biophys Acta Mol Cell Res 1868(2):118893. https:\/\/doi.org\/10.1016\/j.bbamcr.2020.118893","journal-title":"Biochim Biophys Acta Mol Cell Res"},{"key":"2531_CR29","doi-asserted-by":"publisher","unstructured":"Smolarz B, Lukasiewicz H et al (2025) Lung cancer-epidemiology, pathogenesis, treatment and molecular aspect (review of literature). Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms26052049","DOI":"10.3390\/ijms26052049"},{"issue":"1","key":"2531_CR30","doi-asserted-by":"publisher","first-page":"6523","DOI":"10.1038\/s41467-023-42025-8","volume":"14","author":"L Sun","year":"2023","unstructured":"Sun L, Zhang Y et al (2023) Lactylation of METTL16 promotes cuproptosis via m(6)A-modification on FDX1 mRNA in gastric cancer. Nat Commun 14(1):6523. https:\/\/doi.org\/10.1038\/s41467-023-42025-8","journal-title":"Nat Commun"},{"issue":"5","key":"2531_CR31","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1038\/s41571-024-00876-0","volume":"21","author":"D Tang","year":"2024","unstructured":"Tang D, Kroemer G et al (2024) Targeting cuproplasia and cuproptosis in cancer. Nat Rev Clin Oncol 21(5):370\u2013388. https:\/\/doi.org\/10.1038\/s41571-024-00876-0","journal-title":"Nat Rev Clin Oncol"},{"key":"2531_CR32","doi-asserted-by":"publisher","first-page":"111883","DOI":"10.1016\/j.cellsig.2025.111883","volume":"134","author":"L Tang","year":"2025","unstructured":"Tang L, Xie B et al (2025) Transcriptional regulation of ATOX1 by PRRX2 impacts the progression and cuproptosis of hepatocellular carcinoma. Cell Signal 134:111883. https:\/\/doi.org\/10.1016\/j.cellsig.2025.111883","journal-title":"Cell Signal"},{"issue":"6586","key":"2531_CR33","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1126\/science.abf0529","volume":"375","author":"P Tsvetkov","year":"2022","unstructured":"Tsvetkov P, Coy S et al (2022) Copper induces cell death by targeting lipoylated TCA cycle proteins. Science 375(6586):1254\u20131261. https:\/\/doi.org\/10.1126\/science.abf0529","journal-title":"Science"},{"issue":"7","key":"2531_CR34","doi-asserted-by":"publisher","first-page":"1193","DOI":"10.1136\/gutjnl-2019-319639","volume":"69","author":"Q Wang","year":"2020","unstructured":"Wang Q, Chen C et al (2020) METTL3-mediated m(6)A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance. Gut 69(7):1193\u20131205. https:\/\/doi.org\/10.1136\/gutjnl-2019-319639","journal-title":"Gut"},{"issue":"10","key":"2531_CR35","doi-asserted-by":"publisher","first-page":"1908","DOI":"10.1080\/01635581.2020.1817957","volume":"73","author":"W Wang","year":"2021","unstructured":"Wang W, Wang X et al (2021) Serum copper level and the copper-to-zinc ratio could be useful in the prediction of lung cancer and its prognosis: a case-control study in Northeast China. Nutr Cancer 73(10):1908\u20131915. https:\/\/doi.org\/10.1080\/01635581.2020.1817957","journal-title":"Nutr Cancer"},{"issue":"1","key":"2531_CR36","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1186\/s12943-023-01810-1","volume":"22","author":"Y Wang","year":"2023","unstructured":"Wang Y, Wang Y et al (2023) Epigenetic modification of m(6)A regulator proteins in cancer. Mol Cancer 22(1):102. https:\/\/doi.org\/10.1186\/s12943-023-01810-1","journal-title":"Mol Cancer"},{"issue":"9","key":"2531_CR37","doi-asserted-by":"publisher","first-page":"1328","DOI":"10.1016\/j.jtho.2025.04.016","volume":"20","author":"M Wiesweg","year":"2025","unstructured":"Wiesweg M, Alaffas A et al (2025) Treatment sequences in BRAF-V600-mutated NSCLC: first-line targeted therapy versus first-line (chemo-) immunotherapy. J Thorac Oncol 20(9):1328\u20131335. https:\/\/doi.org\/10.1016\/j.jtho.2025.04.016","journal-title":"J Thorac Oncol"},{"issue":"1","key":"2531_CR38","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1186\/s11658-024-00623-4","volume":"29","author":"Y Xiao","year":"2024","unstructured":"Xiao Y, Yin J et al (2024) Triptolide-induced cuproptosis is a novel antitumor strategy for the treatment of cervical cancer. Cell Mol Biol Lett 29(1):113. https:\/\/doi.org\/10.1186\/s11658-024-00623-4","journal-title":"Cell Mol Biol Lett"},{"issue":"1","key":"2531_CR39","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1186\/s12943-023-01732-y","volume":"22","author":"J Xie","year":"2023","unstructured":"Xie J, Yang Y et al (2023) Cuproptosis: mechanisms and links with cancers. Mol Cancer 22(1):46. https:\/\/doi.org\/10.1186\/s12943-023-01732-y","journal-title":"Mol Cancer"},{"key":"2531_CR40","doi-asserted-by":"publisher","first-page":"114165","DOI":"10.1016\/j.intimp.2025.114165","volume":"148","author":"R Xue","year":"2025","unstructured":"Xue R, Qin C et al (2025) SRF\/SLC31A1 signaling promotes cuproptosis induced by celastrol in NSCLC. Int Immunopharmacol 148:114165. https:\/\/doi.org\/10.1016\/j.intimp.2025.114165","journal-title":"Int Immunopharmacol"},{"issue":"12","key":"2531_CR41","doi-asserted-by":"publisher","first-page":"6160","DOI":"10.1016\/j.ymthe.2025.09.004","volume":"33","author":"Q Yu","year":"2025","unstructured":"Yu Q, Jiang K et al (2025) Elesclomol-copper combination synergistically targets mitochondrial metabolism in cancer stem cells to overcome chemoresistance in PDAC. Mol Ther 33(12):6160\u20136177. https:\/\/doi.org\/10.1016\/j.ymthe.2025.09.004","journal-title":"Mol Ther"},{"issue":"12","key":"2531_CR42","doi-asserted-by":"publisher","first-page":"2901","DOI":"10.1158\/0008-5472.CAN-15-2120","volume":"6","author":"E Zhang","year":"2016","unstructured":"Zhang E, Shen B et al (2016) Ubiquitin-specific protease 11 (USP11) functions as a tumor suppressor through deubiquitinating and stabilizing VGLL4 protein. Am J Cancer Res 6(12):2901\u20132909","journal-title":"Am J Cancer Res"},{"issue":"4","key":"2531_CR43","doi-asserted-by":"publisher","first-page":"1391","DOI":"10.7150\/ijbs.104097","volume":"21","author":"J Zhang","year":"2025","unstructured":"Zhang J, Zhang M et al (2025) N(6)-methyladenosine reader IGF2BP2-modified HMMR promotes non-small cell lung cancer metastasis via interaction with MAP4K4. Int J Biol Sci 21(4):1391\u20131409. https:\/\/doi.org\/10.7150\/ijbs.104097","journal-title":"Int J Biol Sci"},{"issue":"3","key":"2531_CR44","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1007\/s00109-024-02417-9","volume":"102","author":"Y Zhao","year":"2024","unstructured":"Zhao Y, Huang J et al (2024) Ubiquitination and deubiquitination in the regulation of N(6)-methyladenosine functional molecules. J Mol Med 102(3):337\u2013351. https:\/\/doi.org\/10.1007\/s00109-024-02417-9","journal-title":"J Mol Med (Berl)"},{"key":"2531_CR45","doi-asserted-by":"publisher","first-page":"117257","DOI":"10.1016\/j.taap.2025.117257","volume":"496","author":"Y Zhao","year":"2025","unstructured":"Zhao Y, Wang R et al (2025) Complanatoside A disrupts copper homeostasis and induces cuproptosis via directly targeting ATOX1 in prostate cancer. Toxicol Appl Pharmacol 496:117257. https:\/\/doi.org\/10.1016\/j.taap.2025.117257","journal-title":"Toxicol Appl Pharmacol"},{"issue":"7","key":"2531_CR46","doi-asserted-by":"publisher","first-page":"e70050","DOI":"10.1111\/cpr.70050","volume":"58","author":"G Zhou","year":"2025","unstructured":"Zhou G, Tan J et al (2025) Mechanistic insights and therapeutic potentials of ubiquitin-proteasome system in non-small cell lung cancer. Cell Prolif 58(7):e70050. https:\/\/doi.org\/10.1111\/cpr.70050","journal-title":"Cell Prolif"}],"container-title":["Molecular Genetics and Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00438-026-02531-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00438-026-02531-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00438-026-02531-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:15:42Z","timestamp":1792066542000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00438-026-02531-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,15]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["2531"],"URL":"https:\/\/doi.org\/10.1007\/s00438-026-02531-y","relation":{},"ISSN":["1617-4615","1617-4623"],"issn-type":[{"value":"1617-4615","type":"print"},{"value":"1617-4623","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,15]]},"assertion":[{"value":"20 April 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 October 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"203"}}