{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T05:45:11Z","timestamp":1790401511493,"version":"4.1.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2009,8,26]],"date-time":"2009-08-26T00:00:00Z","timestamp":1251244800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum Genet"],"published-print":{"date-parts":[[2010,1]]},"DOI":"10.1007\/s00439-009-0736-4","type":"journal-article","created":{"date-parts":[[2009,8,25]],"date-time":"2009-08-25T11:34:37Z","timestamp":1251200077000},"page":"19-31","source":"Crossref","is-referenced-by-count":34,"title":["Deletion of an enhancer near DLX5 and DLX6 in a family with hearing loss, craniofacial defects, and an inv(7)(q21.3q35)"],"prefix":"10.1007","volume":"127","author":[{"given":"Kerry K.","family":"Brown","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob A.","family":"Reiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Crow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather L.","family":"Ferguson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"Fritzsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia C.","family":"Morton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2009,8,26]]},"reference":[{"key":"736_CR1","doi-asserted-by":"crossref","first-page":"3795","DOI":"10.1242\/dev.126.17.3795","volume":"126","author":"D Acampora","year":"1999","unstructured":"Acampora D, Merlo GR, Paleari L, Zerega B, Postiglione MP, Mantero S, Bober E, Barbieri O, Simeone A, Levi G (1999) Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5. Development 126:3795\u20133809","journal-title":"Development"},{"key":"736_CR2","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.ajhg.2007.09.005","volume":"82","author":"M Alarcon","year":"2008","unstructured":"Alarcon M, Abrahams BS, Stone JL, Duvall JA, Perederiy JV, Bomar JM, Sebat J, Wigler M, Martin CL, Ledbetter DH, Nelson SF, Cantor RM, Geschwind DH (2008) Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene. Am J Hum Genet 82:150\u2013159","journal-title":"Am J Hum Genet"},{"key":"736_CR3","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","volume":"215","author":"SF Altschul","year":"1990","unstructured":"Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ (1990) Basic local alignment search tool. J Mol Biol 215:403\u2013410","journal-title":"J Mol Biol"},{"key":"736_CR4","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0896-6273(00)80345-1","volume":"19","author":"SA Anderson","year":"1997","unstructured":"Anderson SA, Qiu M, Bulfone A, Eisenstat DD, Meneses J, Pedersen R, Rubenstein JL (1997) Mutations of the homeobox genes Dlx-1 and Dlx-2 disrupt the striatal subventricular zone and differentiation of late born striatal neurons. Neuron 19:27\u201337","journal-title":"Neuron"},{"key":"736_CR5","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.ajhg.2007.09.015","volume":"82","author":"DE Arking","year":"2008","unstructured":"Arking DE, Cutler DJ, Brune CW, Teslovich TM, West K, Ikeda M, Rea A, Guy M, Lin S, Cook EH, Chakravarti A (2008) A common genetic variant in the neurexin superfamily member CNTNAP2 increases familial risk of autism. Am J Hum Genet 82:160\u2013164","journal-title":"Am J Hum Genet"},{"key":"736_CR6","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.ydbio.2005.11.013","volume":"291","author":"S Bagheri-Fam","year":"2006","unstructured":"Bagheri-Fam S, Barrionuevo F, Dohrmann U, Gunther T, Schule R, Kemler R, Mallo M, Kanzler B, Scherer G (2006) Long-range upstream and downstream enhancers control distinct subsets of the complex spatiotemporal Sox9 expression pattern. Dev Biol 291:382\u2013397","journal-title":"Dev Biol"},{"key":"736_CR7","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.ajhg.2007.09.017","volume":"82","author":"B Bakkaloglu","year":"2008","unstructured":"Bakkaloglu B, O\u2019Roak BJ, Louvi A, Gupta AR, Abelson JF, Morgan TM, Chawarska K, Klin A, Ercan-Sencicek AG, Stillman AA, Tanriover G, Abrahams BS, Duvall JA, Robbins EM, Geschwind DH, Biederer T, Gunel M, Lifton RP, State MW (2008) Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disorders. Am J Hum Genet 82:165\u2013173","journal-title":"Am J Hum Genet"},{"key":"736_CR8","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1038\/ng1196-353","volume":"14","author":"E Belloni","year":"1996","unstructured":"Belloni E, Muenke M, Roessler E, Traverso G, Siegel-Bartelt J, Frumkin A, Mitchell HF, Donis-Keller H, Helms C, Hing AV, Heng HH, Koop B, Martindale D, Rommens JM, Tsui LC, Scherer SW (1996) Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly. Nat Genet 14:353\u2013356","journal-title":"Nat Genet"},{"key":"736_CR9","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1038\/sj.ejhg.5201824","volume":"15","author":"JM Belloso","year":"2007","unstructured":"Belloso JM, Bache I, Guitart M, Caballin MR, Halgren C, Kirchhoff M, Ropers HH, Tommerup N, Tumer Z (2007) Disruption of the CNTNAP2 gene in a t(7;15) translocation family without symptoms of Gilles de la Tourette syndrome. Eur J Hum Genet 15:711\u2013713","journal-title":"Eur J Hum Genet"},{"key":"736_CR10","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1101\/gr.789803","volume":"13","author":"N Bray","year":"2003","unstructured":"Bray N, Dubchak I, Pachter L (2003) AVID: a global alignment program. Genome Res 13:97\u2013102","journal-title":"Genome Res"},{"key":"736_CR11","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1101\/gr.762503","volume":"13","author":"O Couronne","year":"2003","unstructured":"Couronne O, Poliakov A, Bray N, Ishkhanov T, Ryaboy D, Rubin E, Pachter L, Dubchak I (2003) Strategies and tools for whole-genome alignments. Genome Res 13:73\u201380","journal-title":"Genome Res"},{"key":"736_CR12","doi-asserted-by":"crossref","first-page":"3831","DOI":"10.1242\/dev.126.17.3831","volume":"126","author":"MJ Depew","year":"1999","unstructured":"Depew MJ, Liu JK, Long JE, Presley R, Meneses JJ, Pedersen RA, Rubenstein JL (1999) Dlx5 regulates regional development of the branchial arches and sensory capsules. Development 126:3831\u20133846","journal-title":"Development"},{"key":"736_CR13","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1038\/sj.mp.4002049","volume":"13","author":"JI Friedman","year":"2008","unstructured":"Friedman JI, Vrijenhoek T, Markx S, Janssen IM, van der Vliet WA, Faas BH, Knoers NV, Cahn W, Kahn RS, Edelmann L, Davis KL, Silverman JM, Brunner HG, van Kessel AG, Wijmenga C, Ophoff RA, Veltman JA (2008) CNTNAP2 gene dosage variation is associated with schizophrenia and epilepsy. Mol Psychiatry 13:261\u2013266","journal-title":"Mol Psychiatry"},{"key":"736_CR14","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/S0165-5876(03)00193-9","volume":"67","author":"K Fukushima","year":"2003","unstructured":"Fukushima K, Nagai K, Tsukada H, Sugata A, Sugata K, Kasai N, Kibayashi N, Maeda Y, Gunduz M, Nishizaki K (2003) Deletion mapping of split hand\/split foot malformation with hearing impairment: a case report. Int J Pediatr Otorhinolaryngol 67:1127\u20131132","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"736_CR15","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1002\/ajmg.a.31563","volume":"143","author":"CA Gurnett","year":"2007","unstructured":"Gurnett CA, Bowcock AM, Dietz FR, Morcuende JA, Murray JC, Dobbs MB (2007) Two novel point mutations in the long-range SHH enhancer in three families with triphalangeal thumb and preaxial polydactyly. Am J Med Genet A 143:27\u201332","journal-title":"Am J Med Genet A"},{"key":"736_CR16","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1136\/jmg.38.6.405","volume":"38","author":"E Haberlandt","year":"2001","unstructured":"Haberlandt E, Loffler J, Hirst-Stadlmann A, Stockl B, Judmaier W, Fischer H, Heinz-Erian P, Muller T, Utermann G, Smith RJ, Janecke AR (2001) Split hand\/split foot malformation associated with sensorineural deafness, inner and middle ear malformation, hypodontia, congenital vertical talus, and deletion of eight microsatellite markers in 7q21.1\u2013q21.3. J Med Genet 38:405\u2013409","journal-title":"J Med Genet"},{"key":"736_CR17","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/ng1491","volume":"37","author":"S Horike","year":"2005","unstructured":"Horike S, Cai S, Miyano M, Cheng JF, Kohwi-Shigematsu T (2005) Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome. Nat Genet 37:31\u201340","journal-title":"Nat Genet"},{"key":"736_CR18","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1242\/dev.02239","volume":"133","author":"Y Jeong","year":"2006","unstructured":"Jeong Y, El-Jaick K, Roessler E, Muenke M, Epstein DJ (2006) A functional screen for sonic hedgehog regulatory elements across a 1\u00a0Mb interval identifies long-range ventral forebrain enhancers. Development 133:761\u2013772","journal-title":"Development"},{"key":"736_CR19","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1086\/426833","volume":"76","author":"DA Kleinjan","year":"2005","unstructured":"Kleinjan DA, van Heyningen V (2005) Long-range control of gene expression: emerging mechanisms and disruption in disease. Am J Hum Genet 76:8\u201332","journal-title":"Am J Hum Genet"},{"key":"736_CR20","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.ydbio.2006.08.060","volume":"299","author":"DA Kleinjan","year":"2006","unstructured":"Kleinjan DA, Seawright A, Mella S, Carr CB, Tyas DA, Simpson TI, Mason JO, Price DJ, van Heyningen V (2006) Long-range downstream enhancers are essential for Pax6 expression. Dev Biol 299:563\u2013581","journal-title":"Dev Biol"},{"key":"736_CR21","doi-asserted-by":"crossref","first-page":"7548","DOI":"10.1073\/pnas.112212199","volume":"99","author":"LA Lettice","year":"2002","unstructured":"Lettice LA, Horikoshi T, Heaney SJ, van Baren MJ, van der Linde HC, Breedveld GJ, Joosse M, Akarsu N, Oostra BA, Endo N, Shibata M, Suzuki M, Takahashi E, Shinka T, Nakahori Y, Ayusawa D, Nakabayashi K, Scherer SW, Heutink P, Hill RE, Noji S (2002) Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly. Proc Natl Acad Sci USA 99:7548\u20137553","journal-title":"Proc Natl Acad Sci USA"},{"key":"736_CR22","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1093\/hmg\/ddg180","volume":"12","author":"LA Lettice","year":"2003","unstructured":"Lettice LA, Heaney SJ, Purdie LA, Li L, de Beer P, Oostra BA, Goode D, Elgar G, Hill RE, de Graaff E (2003) A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly. Hum Mol Genet 12:1725\u20131735","journal-title":"Hum Mol Genet"},{"key":"736_CR23","first-page":"619","volume":"44","author":"GR Merlo","year":"2000","unstructured":"Merlo GR, Zerega B, Paleari L, Trombino S, Mantero S, Levi G (2000) Multiple functions of Dlx genes. Int J Dev Biol 44:619\u2013626","journal-title":"Int J Dev Biol"},{"key":"736_CR24","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/gene.10098","volume":"33","author":"GR Merlo","year":"2002","unstructured":"Merlo GR, Paleari L, Mantero S, Genova F, Beverdam A, Palmisano GL, Barbieri O, Levi G (2002a) Mouse model of split hand\/foot malformation type I. Genesis 33:97\u2013101","journal-title":"Genesis"},{"key":"736_CR25","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1006\/dbio.2002.0713","volume":"248","author":"GR Merlo","year":"2002","unstructured":"Merlo GR, Paleari L, Mantero S, Zerega B, Adamska M, Rinkwitz S, Bober E, Levi G (2002b) The Dlx5 homeobox gene is essential for vestibular morphogenesis in the mouse embryo through a BMP4-mediated pathway. Dev Biol 248:157\u2013169","journal-title":"Dev Biol"},{"key":"736_CR26","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1111\/j.1582-4934.2008.00377.x","volume":"12","author":"M Miyano","year":"2008","unstructured":"Miyano M, Horike S, Cai S, Oshimura M, Kohwi-Shigematsu T (2008) DLX5 expression is monoallelic and Dlx5 is up-regulated in the Mecp2-null frontal cortex. J Cell Mol Med 12:1188\u20131191","journal-title":"J Cell Mol Med"},{"key":"736_CR27","doi-asserted-by":"crossref","first-page":"5604","DOI":"10.1128\/MCB.13.9.5604","volume":"13","author":"PA Ney","year":"1993","unstructured":"Ney PA, Andrews NC, Jane SM, Safer B, Purucker ME, Weremowicz S, Morton CC, Goff SC, Orkin SH, Nienhuis AW (1993) Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner. Mol Cell Biol 13:5604\u20135612","journal-title":"Mol Cell Biol"},{"key":"736_CR28","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/nature05295","volume":"444","author":"LA Pennacchio","year":"2006","unstructured":"Pennacchio LA, Ahituv N, Moses AM, Prabhakar S, Nobrega MA, Shoukry M, Minovitsky S, Dubchak I, Holt A, Lewis KD, Plajzer-Frick I, Akiyama J, De Val S, Afzal V, Black BL, Couronne O, Eisen MB, Visel A, Rubin EM (2006) In vivo enhancer analysis of human conserved non-coding sequences. Nature 444:499\u2013502","journal-title":"Nature"},{"key":"736_CR29","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/S0896-6273(00)81049-1","volume":"24","author":"S Poliak","year":"1999","unstructured":"Poliak S, Gollan L, Martinez R, Custer A, Einheber S, Salzer JL, Trimmer JS, Shrager P, Peles E (1999) Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels. Neuron 24:1037\u20131047","journal-title":"Neuron"},{"key":"736_CR30","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1083\/jcb.200305018","volume":"162","author":"S Poliak","year":"2003","unstructured":"Poliak S, Salomon D, Elhanany H, Sabanay H, Kiernan B, Pevny L, Stewart CL, Xu X, Chiu SY, Shrager P, Furley AJ, Peles E (2003) Juxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1. J Cell Biol 162:1149\u20131160","journal-title":"J Cell Biol"},{"key":"736_CR31","doi-asserted-by":"crossref","first-page":"4878","DOI":"10.1093\/nar\/23.23.4878","volume":"23","author":"K Quandt","year":"1995","unstructured":"Quandt K, Frech K, Karas H, Wingender E, Werner T (1995) MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res 23:4878\u20134884","journal-title":"Nucleic Acids Res"},{"key":"736_CR32","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1101\/gad.988402","volume":"16","author":"RF Robledo","year":"2002","unstructured":"Robledo RF, Rajan L, Li X, Lufkin T (2002) The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. Genes Dev 16:1089\u20131101","journal-title":"Genes Dev"},{"key":"736_CR33","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/ng1196-357","volume":"14","author":"E Roessler","year":"1996","unstructured":"Roessler E, Belloni E, Gaudenz K, Jay P, Berta P, Scherer SW, Tsui LC, Muenke M (1996) Mutations in the human Sonic Hedgehog gene cause holoprosencephaly. Nat Genet 14:357\u2013360","journal-title":"Nat Genet"},{"key":"736_CR34","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1007\/s004390050486","volume":"100","author":"E Roessler","year":"1997","unstructured":"Roessler E, Ward DE, Gaudenz K, Belloni E, Scherer SW, Donnai D, Siegel-Bartelt J, Tsui LC, Muenke M (1997) Cytogenetic rearrangements involving the loss of the Sonic Hedgehog gene at 7q36 cause holoprosencephaly. Hum Genet 100:172\u2013181","journal-title":"Hum Genet"},{"key":"736_CR35","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.ejmg.2008.06.010","volume":"51","author":"E Rossi","year":"2008","unstructured":"Rossi E, Verri AP, Patricelli MG, Destefani V, Ricca I, Vetro A, Ciccone R, Giorda R, Toniolo D, Maraschio P, Zuffardi O (2008) A 12\u00a0Mb deletion at 7q33\u2013q35 associated with autism spectrum disorders and primary amenorrhea. Eur J Med Genet 51:631\u2013638","journal-title":"Eur J Med Genet"},{"key":"736_CR36","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1093\/hmg\/3.8.1345","volume":"3","author":"SW Scherer","year":"1994","unstructured":"Scherer SW, Poorkaj P, Massa H, Soder S, Allen T, Nunes M, Geshuri D, Wong E, Belloni E, Little S et al (1994) Physical mapping of the split hand\/split foot locus on chromosome 7 and implication in syndromic ectrodactyly. Hum Mol Genet 3:1345\u20131354","journal-title":"Hum Mol Genet"},{"key":"736_CR37","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1086\/520063","volume":"81","author":"B Schule","year":"2007","unstructured":"Schule B, Li HH, Fisch-Kohl C, Purmann C, Francke U (2007) DLX5 and DLX6 expression is biallelic and not modulated by MeCP2 deficiency. Am J Hum Genet 81:492\u2013506","journal-title":"Am J Hum Genet"},{"key":"736_CR38","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1093\/nar\/23.6.1087","volume":"23","author":"PD Siebert","year":"1995","unstructured":"Siebert PD, Chenchik A, Kellogg DE, Lukyanov KA, Lukyanov SA (1995) An improved PCR method for walking in uncloned genomic DNA. Nucleic Acids Res 23:1087\u20131088","journal-title":"Nucleic Acids Res"},{"key":"736_CR39","doi-asserted-by":"crossref","first-page":"2250","DOI":"10.1073\/pnas.91.6.2250","volume":"91","author":"A Simeone","year":"1994","unstructured":"Simeone A, Acampora D, Pannese M, D\u2019Esposito M, Stornaiuolo A, Gulisano M, Mallamaci A, Kastury K, Druck T, Huebner K et al (1994) Cloning and characterization of two members of the vertebrate Dlx gene family. Proc Natl Acad Sci USA 91:2250\u20132254","journal-title":"Proc Natl Acad Sci USA"},{"key":"736_CR40","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1056\/NEJMoa052773","volume":"354","author":"KA Strauss","year":"2006","unstructured":"Strauss KA, Puffenberger EG, Huentelman MJ, Gottlieb S, Dobrin SE, Parod JM, Stephan DA, Morton DH (2006) Recessive symptomatic focal epilepsy and mutant contactin-associated protein-like 2. N Engl J Med 354:1370\u20131377","journal-title":"N Engl J Med"},{"key":"736_CR41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0888-7543(03)00097-1","volume":"82","author":"AJ Verkerk","year":"2003","unstructured":"Verkerk AJ, Mathews CA, Joosse M, Eussen BH, Heutink P, Oostra BA (2003) CNTNAP2 is disrupted in a family with Gilles de la Tourette syndrome and obsessive compulsive disorder. Genomics 82:1\u20139","journal-title":"Genomics"},{"key":"736_CR42","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.devcel.2007.03.007","volume":"12","author":"MP Verzi","year":"2007","unstructured":"Verzi MP, Agarwal P, Brown C, McCulley DJ, Schwarz JJ, Black BL (2007) The transcription factor MEF2C is required for craniofacial development. Dev Cell 12:645\u2013652","journal-title":"Dev Cell"},{"key":"736_CR43","doi-asserted-by":"crossref","first-page":"e54","DOI":"10.1136\/jmg.2003.010587","volume":"41","author":"I Wieland","year":"2004","unstructured":"Wieland I, Muschke P, Jakubiczka S, Volleth M, Freigang B, Wieacker PF (2004) Refinement of the deletion in 7q21.3 associated with split hand\/foot malformation type 1 and Mondini dysplasia. J Med Genet 41:e54","journal-title":"J Med Genet"},{"key":"736_CR44","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1523\/JNEUROSCI.20-02-00709.2000","volume":"20","author":"T Zerucha","year":"2000","unstructured":"Zerucha T, Stuhmer T, Hatch G, Park BK, Long Q, Yu G, Gambarotta A, Schultz JR, Rubenstein JL, Ekker M (2000) A highly conserved enhancer in the Dlx5\/Dlx6 intergenic region is the site of cross-regulatory interactions between Dlx genes in the embryonic forebrain. J Neurosci 20:709\u2013721","journal-title":"J Neurosci"}],"container-title":["Human Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00439-009-0736-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00439-009-0736-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00439-009-0736-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,10]],"date-time":"2021-10-10T01:05:47Z","timestamp":1633827947000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00439-009-0736-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8,26]]},"references-count":44,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1]]}},"alternative-id":["736"],"URL":"https:\/\/doi.org\/10.1007\/s00439-009-0736-4","relation":{},"ISSN":["0340-6717","1432-1203"],"issn-type":[{"value":"0340-6717","type":"print"},{"value":"1432-1203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,8,26]]}}}