{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T18:03:03Z","timestamp":1778868183807,"version":"3.51.4"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2010,10,20]],"date-time":"2010-10-20T00:00:00Z","timestamp":1287532800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum Genet"],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1007\/s00439-010-0898-0","type":"journal-article","created":{"date-parts":[[2010,10,19]],"date-time":"2010-10-19T06:00:10Z","timestamp":1287468010000},"page":"111-113","source":"Crossref","is-referenced-by-count":27,"title":["\u221213915*G DNA polymorphism associated with lactase persistence in Africa interacts with Oct-1"],"prefix":"10.1007","volume":"129","author":[{"given":"Lynne C.","family":"Olds","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Kun","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Sibley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,10,20]]},"reference":[{"issue":"2","key":"898_CR1","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/ng826","volume":"30","author":"NS Enattah","year":"2002","unstructured":"Enattah NS, Sahi T, Savilahti E, Terwilliger JD, Peltonen L, Jarvela I (2002) Identification of a variant associated with adult-type hypolactasia. Nat Genet 30(2):233\u2013237","journal-title":"Nat Genet"},{"issue":"1","key":"898_CR2","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.ajhg.2007.09.012","volume":"82","author":"NS Enattah","year":"2008","unstructured":"Enattah NS, Jensen TG, Nielsen M, Lewinski R, Kuokkanen M, Rasinpera H, El-Shanti H, Seo JK, Alifrangis M, Khalil IF, Natah A, Ali A, Natah S, Comas D, Mehdi SQ, Groop L, Vestergaard EM, Imtiaz F, Rashed MS, Meyer B, Troelsen J, Peltonen L (2008) Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture. Am J Hum Genet 82(1):57\u201372","journal-title":"Am J Hum Genet"},{"issue":"1\u20132","key":"898_CR3","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1111\/j.1432-1033.1994.tb19969.x","volume":"219","author":"HP Hauri","year":"1994","unstructured":"Hauri HP, Sander B, Naim H (1994) Induction of lactase biosynthesis in the human intestinal epithelial cell line caco-2. Eur J Biochem 219(1\u20132):539\u2013546","journal-title":"Eur J Biochem"},{"issue":"6","key":"898_CR4","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1007\/s00439-006-0291-1","volume":"120","author":"CJ Ingram","year":"2007","unstructured":"Ingram CJ, Elamin MF, Mulcare CA, Weale ME, Tarekegn A, Raga TO, Bekele E, Elamin FM, Thomas MG, Bradman N, Swallow DM (2007) A novel polymorphism associated with lactose tolerance in Africa: multiple causes for lactase persistence? Hum Genet 120(6):779\u2013788","journal-title":"Hum Genet"},{"issue":"24","key":"898_CR5","doi-asserted-by":"crossref","first-page":"3945","DOI":"10.1093\/hmg\/ddi418","volume":"14","author":"RH Lewinsky","year":"2005","unstructured":"Lewinsky RH, Jensen TG, Moller J, Stensballe A, Olsen J, Troelsen JT (2005) T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro. Hum Mol Genet 14(24):3945\u20133953","journal-title":"Hum Mol Genet"},{"issue":"18","key":"898_CR6","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1093\/hmg\/ddg244","volume":"12","author":"LC Olds","year":"2003","unstructured":"Olds LC, Sibley E (2003) Lactase persistence DNA variant enhances lactase promoter activity in vitro: functional role as a cis regulatory element. Hum Mol Genet 12(18):2333\u20132340","journal-title":"Hum Mol Genet"},{"issue":"1","key":"898_CR7","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/ng1946","volume":"39","author":"SA Tishkoff","year":"2007","unstructured":"Tishkoff SA, Reed FA, Ranciaro A, Voight BF, Babbitt CC, Silverman JS, Powell K, Mortensen HM, Hirbo JB, Osman M, Ibrahim M, Omar SA, Lema G, Nyambo TB, Ghori J, Bumpstead S, Pritchard JK, Wray GA, Deloukas P (2007) Convergent adaptation of human lactase persistence in Africa and Europe. Nat Genet 39(1):31\u201340","journal-title":"Nat Genet"},{"issue":"6","key":"898_CR8","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1053\/j.gastro.2003.09.031","volume":"125","author":"JT Troelsen","year":"2003","unstructured":"Troelsen JT, Olsen J, Moller J, Sjostrom H (2003) An upstream polymorphism associated with lactase persistence has increased enhancer activity. Gastroenterology 125(6):1686\u20131694","journal-title":"Gastroenterology"}],"container-title":["Human Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00439-010-0898-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00439-010-0898-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00439-010-0898-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T23:26:08Z","timestamp":1559085968000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00439-010-0898-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10,20]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["898"],"URL":"https:\/\/doi.org\/10.1007\/s00439-010-0898-0","relation":{},"ISSN":["0340-6717","1432-1203"],"issn-type":[{"value":"0340-6717","type":"print"},{"value":"1432-1203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10,20]]}}}