{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T17:07:40Z","timestamp":1770484060340,"version":"3.49.0"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2012,10,30]],"date-time":"2012-10-30T00:00:00Z","timestamp":1351555200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum Genet"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1007\/s00439-012-1236-5","type":"journal-article","created":{"date-parts":[[2012,10,29]],"date-time":"2012-10-29T19:14:05Z","timestamp":1351538045000},"page":"189-199","source":"Crossref","is-referenced-by-count":57,"title":["Suggestion of GLYAT gene underlying variation of bone size and body lean mass as revealed by a bivariate genome-wide association study"],"prefix":"10.1007","volume":"132","author":[{"given":"Yan-Fang","family":"Guo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Shu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong-Jun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong-Gang","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Tian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tie-Lin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang-Lei","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng","family":"Dai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong-Wen","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,10,30]]},"reference":[{"key":"1236_CR1","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1056\/NEJMoa022464","volume":"349","author":"HG Ahlborg","year":"2003","unstructured":"Ahlborg HG, Johnell O, Turner CH, Rannevik G, Karlsson MK (2003) Bone loss and bone size after menopause. N Engl J Med 349:327\u2013334","journal-title":"N Engl J Med"},{"key":"1236_CR2","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1093\/brain\/awl023","volume":"129","author":"M Bakay","year":"2006","unstructured":"Bakay M, Wang Z, Melcon G, Schiltz L, Xuan J, Zhao P, Sartorelli V, Seo J, Pegoraro E, Angelini C, Shneiderman B, Escolar D, Chen YW, Winokur ST, Pachman LM, Fan C, Mandler R, Nevo Y, Gordon E, Zhu Y, Dong Y, Wang Y, Hoffman EP (2006) Nuclear envelope dystrophies show a transcriptional fingerprint suggesting disruption of Rb-MyoD pathways in muscle regeneration. Brain 129:996\u20131013","journal-title":"Brain"},{"key":"1236_CR3","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S8756-3282(00)00426-9","volume":"28","author":"E Balint","year":"2001","unstructured":"Balint E, Szabo P, Marshall CF, Sprague SM (2001) Glucose-induced inhibition of in vitro bone mineralization. Bone 28:21\u201328","journal-title":"Bone"},{"key":"1236_CR4","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/s00774-011-0294-4","volume":"30","author":"F Baptista","year":"2012","unstructured":"Baptista F, Barrigas C, Vieira F, Santa-Clara H, Homens PM, Fragoso I, Teixeira PJ, Sardinha LB (2012) The role of lean body mass and physical activity in bone health in children. J Bone Miner Metab 30:100\u2013108","journal-title":"J Bone Miner Metab"},{"key":"1236_CR5","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/bioinformatics\/bth457","volume":"21","author":"JC Barrett","year":"2005","unstructured":"Barrett JC, Fry B, Maller J, Daly MJ (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21:263\u2013265","journal-title":"Bioinformatics"},{"key":"1236_CR6","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1097\/gme.0b013e318164ee85","volume":"15","author":"RF Capozza","year":"2008","unstructured":"Capozza RF, Cure-Cure C, Cointry GR, Meta M, Cure P, Rittweger J, Ferretti JL (2008) Association between low lean body mass and osteoporotic fractures after menopause. Menopause 15:905\u2013913","journal-title":"Menopause"},{"key":"1236_CR7","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1093\/ajcn\/75.6.1012","volume":"75","author":"WC Chumlea","year":"2002","unstructured":"Chumlea WC, Wisemandle W, Guo SS, Siervogel RM (2002) Relations between frame size and body composition and bone mineral status. Am J Clin Nutr 75:1012\u20131016","journal-title":"Am J Clin Nutr"},{"key":"1236_CR8","first-page":"1","volume":"4","author":"GR Cointry","year":"2004","unstructured":"Cointry GR, Capozza RF, Negri AL, Roldan EJ, Ferretti JL (2004) Biomechanical background for a noninvasive assessment of bone strength and muscle-bone interactions. J Musculoskelet Neuronal Interact 4:1\u201311","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"1236_CR9","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1385\/JCD:5:1:045","volume":"5","author":"HW Deng","year":"2002","unstructured":"Deng HW, Deng XT, Conway T, Xu FH, Heaney R, Recker RR (2002a) Determination of bone size of hip, spine, and wrist in human pedigrees by genetic and lifestyle factors. J Clin Densitom 5:45\u201356","journal-title":"J Clin Densitom"},{"key":"1236_CR10","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1007\/s007740200052","volume":"20","author":"HW Deng","year":"2002","unstructured":"Deng HW, Xu FH, Davies KM, Heaney R, Recker RR (2002b) Differences in bone mineral density, bone mineral content, and bone areal size in fracturing and non-fracturing women, and their interrelationships at the spine and hip. J Bone Miner Metab 20:358\u2013366","journal-title":"J Bone Miner Metab"},{"key":"1236_CR11","first-page":"263","volume":"1","author":"JL Ferretti","year":"2001","unstructured":"Ferretti JL, Cointry GR, Capozza RF, Capiglioni R, Chiappe MA (2001) Analysis of biomechanical effects on bone and on the muscle-bone interactions in small animal models. J Musculoskelet Neuronal Interact 1:263\u2013274","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"1236_CR12","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0047-6374(02)00194-X","volume":"124","author":"JL Ferretti","year":"2003","unstructured":"Ferretti JL, Cointry GR, Capozza RF, Frost HM (2003) Bone mass, bone strength, muscle-bone interactions, osteopenias and osteoporoses. Mech Ageing Dev 124:269\u2013279","journal-title":"Mech Ageing Dev"},{"key":"1236_CR13","doi-asserted-by":"crossref","first-page":"262","DOI":"10.2174\/1874609811104030260","volume":"4","author":"CS Fry","year":"2011","unstructured":"Fry CS, Rasmussen BB (2011) Skeletal muscle protein balance and metabolism in the elderly. Curr Aging Sci 4:262\u2013268","journal-title":"Curr Aging Sci"},{"key":"1236_CR14","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1177\/1466424007079491","volume":"127","author":"HH Handoll","year":"2007","unstructured":"Handoll HH, Gillespie WJ, Gillespie LD, Madhok R (2007) Moving towards evidence-based healthcare for musculoskeletal injuries: featuring the work of the Cochrane Bone, joint and Muscle Trauma Group. J R Soc Promot Health 127:168\u2013173","journal-title":"J R Soc Promot Health"},{"key":"1236_CR15","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1093\/ajcn\/52.2.214","volume":"52","author":"SB Heymsfield","year":"1990","unstructured":"Heymsfield SB, Smith R, Aulet M, Bensen B, Lichtman S, Wang J, Pierson RN Jr (1990) Appendicular skeletal muscle mass: measurement by dual-photon absorptiometry. Am J Clin Nutr 52:214\u2013218","journal-title":"Am J Clin Nutr"},{"key":"1236_CR16","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1093\/carcin\/bgr187","volume":"32","author":"G Jin","year":"2011","unstructured":"Jin G, Sun J, Isaacs SD, Wiley KE, Kim ST, Chu LW, Zhang Z, Zhao H, Zheng SL, Isaacs WB, Xu J (2011) Human polymorphisms at long non-coding RNAs (lncRNAs) and association with prostate cancer risk. Carcinogenesis 32:1655\u20131659","journal-title":"Carcinogenesis"},{"key":"1236_CR17","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1359\/jbmr.081222","volume":"24","author":"D Karasik","year":"2009","unstructured":"Karasik D, Zhou Y, Cupples LA, Hannan MT, Kiel DP, Demissie S (2009) Bivariate genome-wide linkage analysis of femoral bone traits and leg lean mass: Framingham study. J Bone Miner Res 24:710\u2013718","journal-title":"J Bone Miner Res"},{"key":"1236_CR18","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1093\/ajcn\/76.2.378","volume":"76","author":"J Kim","year":"2002","unstructured":"Kim J, Wang Z, Heymsfield SB, Baumgartner RN, Gallagher D (2002) Total-body skeletal muscle mass: estimation by a new dual-energy X-ray absorptiometry method. Am J Clin Nutr 76:378\u2013383","journal-title":"Am J Clin Nutr"},{"key":"1236_CR19","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.jaut.2009.02.020","volume":"32","author":"Y Kochi","year":"2009","unstructured":"Kochi Y, Suzuki A, Yamada R, Yamamoto K (2009) Genetics of rheumatoid arthritis: underlying evidence of ethnic differences. J Autoimmun 32:158\u2013162","journal-title":"J Autoimmun"},{"key":"1236_CR20","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1111\/j.1532-5415.2011.03472.x","volume":"59","author":"CG Lee","year":"2011","unstructured":"Lee CG, Boyko EJ, Strotmeyer ES, Lewis CE, Cawthon PM, Hoffman AR, Everson-Rose SA, Barrett-Connor E, Orwoll ES (2011) Association between insulin resistance and lean mass loss and fat mass gain in older men without diabetes mellitus. J Am Geriatr Soc 59:1217\u20131224","journal-title":"J Am Geriatr Soc"},{"key":"1236_CR21","doi-asserted-by":"crossref","unstructured":"Lei SF, Shen H, Yang TL, Guo Y, Dong SS, Xu XH, Deng FY, Tian Q, Liu YJ, Liu YZ, Li J, Deng HW (2012) Genome-wide association study identifies HMGN3 locus for spine bone size variation in Chinese. Hum Genet 131:463\u2013469","DOI":"10.1007\/s00439-011-1093-7"},{"key":"1236_CR22","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/oby.2007.531","volume":"15","author":"HJ Leidy","year":"2007","unstructured":"Leidy HJ, Carnell NS, Mattes RD, Campbell WW (2007) Higher protein intake preserves lean mass and satiety with weight loss in pre-obese and obese women. Obesity (Silver Spring) 15:421\u2013429","journal-title":"Obesity (Silver Spring)"},{"key":"1236_CR23","doi-asserted-by":"crossref","first-page":"853","DOI":"10.3109\/00498254.2010.519407","volume":"40","author":"CL Lino Cardenas","year":"2010","unstructured":"Lino Cardenas CL, Bourgine J, Cauffiez C, Allorge D, Lo-Guidice JM, Broly F, Chevalier D (2010) Genetic polymorphisms of glycine N-acyltransferase (GLYAT) in a French Caucasian population. Xenobiotica 40:853\u2013861","journal-title":"Xenobiotica"},{"key":"1236_CR24","doi-asserted-by":"crossref","first-page":"e3160","DOI":"10.1371\/journal.pone.0003160","volume":"3","author":"YZ Liu","year":"2008","unstructured":"Liu YZ, Wilson SG, Wang L, Liu XG, Guo YF, Li J, Yan H, Deloukas P, Soranzo N, Chinappen-Horsley U, Cervino A, Williams FM, Xiong DH, Zhang YP, Jin TB, Levy S, Papasian CJ, Drees BM, Hamilton JJ, Recker RR, Spector TD, Deng HW (2008) Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study. PLoS One 3:e3160","journal-title":"PLoS One"},{"key":"1236_CR25","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/gepi.20372","volume":"33","author":"J Liu","year":"2009","unstructured":"Liu J, Pei Y, Papasian CJ, Deng HW (2009a) Bivariate association analyses for the mixture of continuous and binary traits with the use of extended generalized estimating equations. Genet Epidemiol 33:217\u2013227","journal-title":"Genet Epidemiol"},{"key":"1236_CR26","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.ajhg.2009.02.004","volume":"84","author":"XG Liu","year":"2009","unstructured":"Liu XG, Tan LJ, Lei SF, Liu YJ, Shen H, Wang L, Yan H, Guo YF, Xiong DH, Chen XD, Pan F, Yang TL, Zhang YP, Guo Y, Tang NL, Zhu XZ, Deng HY, Levy S, Recker RR, Papasian CJ, Deng HW (2009b) Genome-wide association and replication studies identified TRHR as an important gene for lean body mass. Am J Hum Genet 84:418\u2013423","journal-title":"Am J Hum Genet"},{"key":"1236_CR27","doi-asserted-by":"crossref","first-page":"e6827","DOI":"10.1371\/journal.pone.0006827","volume":"4","author":"YZ Liu","year":"2009","unstructured":"Liu YZ, Pei YF, Liu JF, Yang F, Guo Y, Zhang L, Liu XG, Yan H, Wang L, Zhang YP, Levy S, Recker RR, Deng HW (2009c) Powerful bivariate genome-wide association analyses suggest the SOX6 gene influencing both obesity and osteoporosis phenotypes in males. PLoS One 4:e6827","journal-title":"PLoS One"},{"key":"1236_CR28","doi-asserted-by":"crossref","first-page":"3171","DOI":"10.1210\/jc.2007-0418","volume":"92","author":"G Livshits","year":"2007","unstructured":"Livshits G, Kato BS, Wilson SG, Spector TD (2007) Linkage of genes to total lean body mass in normal women. J Clin Endocrinol Metab 92:3171\u20133176","journal-title":"J Clin Endocrinol Metab"},{"key":"1236_CR29","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1038\/nbt0410-322","volume":"28","author":"M Lukk","year":"2010","unstructured":"Lukk M, Kapushesky M, Nikkila J, Parkinson H, Goncalves A, Huber W, Ukkonen E, Brazma A (2010) A global map of human gene expression. Nat Biotechnol 28:322\u2013324","journal-title":"Nat Biotechnol"},{"key":"1236_CR30","first-page":"209","volume":"2","author":"RB Martin","year":"2002","unstructured":"Martin RB (2002) Size, structure and gender: lessons about fracture risk. J Musculoskelet Neuronal Interact 2:209\u2013211","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"1236_CR31","doi-asserted-by":"crossref","first-page":"e1000459","DOI":"10.1371\/journal.pgen.1000459","volume":"5","author":"JS Mattick","year":"2009","unstructured":"Mattick JS (2009) The genetic signatures of noncoding RNAs. PLoS Genet 5:e1000459","journal-title":"PLoS Genet"},{"key":"1236_CR32","first-page":"19","volume":"255","author":"E McCloskey","year":"2011","unstructured":"McCloskey E (2011) Preventing osteoporotic fractures in older people. Practitioner 255:19\u201323","journal-title":"Practitioner"},{"key":"1236_CR33","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.1359\/jbmr.2000.15.12.2305","volume":"15","author":"BR McCreadie","year":"2000","unstructured":"McCreadie BR, Goldstein SA (2000) Biomechanics of fracture: is bone mineral density sufficient to assess risk? J Bone Miner Res 15:2305\u20132308","journal-title":"J Bone Miner Res"},{"key":"1236_CR34","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.bone.2010.12.032","volume":"48","author":"LK Micklesfield","year":"2011","unstructured":"Micklesfield LK, Norris SA, Pettifor JM (2011) Determinants of bone size and strength in 13-year-old South African children: the influence of ethnicity, sex and pubertal maturation. Bone 48:777\u2013785","journal-title":"Bone"},{"key":"1236_CR35","first-page":"11","volume":"7","author":"SG Movcessian","year":"1972","unstructured":"Movcessian SG, Boghosian AA, Kamalian RG, Urganjian MK (1972) Effect of Krebs cycle components and glucose on the deamination of mono- and dinucleotides in brain mitochondrial fractions. Vopr Biokhim Mozga 7:11\u201317","journal-title":"Vopr Biokhim Mozga"},{"key":"1236_CR36","doi-asserted-by":"crossref","unstructured":"Orwig DL, Chiles N, Jones M, Hochberg MC (2011) Osteoporosis in men: update 2011. Rheum Dis Clin N Am 37:401\u2013414, vi","DOI":"10.1016\/j.rdc.2011.08.004"},{"key":"1236_CR37","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s10897-007-9134-z","volume":"17","author":"CG Palmer","year":"2008","unstructured":"Palmer CG, Martinez A, Fox M, Sininger Y, Grody WW, Schimmenti LA (2008) Ethnic differences in parental perceptions of genetic testing for deaf infants. J Genet Couns 17:129\u2013138","journal-title":"J Genet Couns"},{"key":"1236_CR38","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1111\/j.1469-1809.2009.00527.x","volume":"73","author":"YF Pei","year":"2009","unstructured":"Pei YF, Zhang L, Liu J, Deng HW (2009) Multivariate association test using haplotype trend regression. Ann Hum Genet 73:456\u2013464","journal-title":"Ann Hum Genet"},{"key":"1236_CR39","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1038\/ng1847","volume":"38","author":"AL Price","year":"2006","unstructured":"Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D (2006) Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 38:904\u2013909","journal-title":"Nat Genet"},{"key":"1236_CR40","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1086\/519795","volume":"81","author":"S Purcell","year":"2007","unstructured":"Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, Maller J, Sklar P, de Bakker PI, Daly MJ, Sham PC (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81:559\u2013575","journal-title":"Am J Hum Genet"},{"key":"1236_CR41","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1097\/GIM.0b013e31817708fa","volume":"10","author":"LA Schimmenti","year":"2008","unstructured":"Schimmenti LA, Martinez A, Telatar M, Lai CH, Shapiro N, Fox M, Warman B, McCarra M, Crandall B, Sininger Y, Grody WW, Palmer CG (2008) Infant hearing loss and connexin testing in a diverse population. Genet Med 10:517\u2013524","journal-title":"Genet Med"},{"key":"1236_CR42","doi-asserted-by":"crossref","first-page":"e115","DOI":"10.1371\/journal.pgen.0030115","volume":"3","author":"A Scuteri","year":"2007","unstructured":"Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J, Najjar S, Nagaraja R, Orru M, Usala G, Dei M, Lai S, Maschio A, Busonero F, Mulas A, Ehret GB, Fink AA, Weder AB, Cooper RS, Galan P, Chakravarti A, Schlessinger D, Cao A, Lakatta E, Abecasis GR (2007) Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet 3:e115","journal-title":"PLoS Genet"},{"key":"1236_CR43","doi-asserted-by":"crossref","first-page":"e27325","DOI":"10.1371\/journal.pone.0027325","volume":"6","author":"L Sun","year":"2011","unstructured":"Sun L, Tan LJ, Lei SF, Chen XD, Li X, Pan R, Yin F, Liu QW, Yan XF, Papasian CJ, Deng HW (2011) Bivariate genome-wide association analyses of femoral neck bone geometry and appendicular lean mass. PLoS One 6:e27325","journal-title":"PLoS One"},{"key":"1236_CR44","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1359\/JBMR.041230","volume":"20","author":"P Szulc","year":"2005","unstructured":"Szulc P, Beck TJ, Marchand F, Delmas PD (2005) Low skeletal muscle mass is associated with poor structural parameters of bone and impaired balance in elderly men\u2014the MINOS study. J Bone Miner Res 20:721\u2013729","journal-title":"J Bone Miner Res"},{"key":"1236_CR45","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1111\/j.1745-7254.2008.00806.x","volume":"29","author":"LJ Tan","year":"2008","unstructured":"Tan LJ, Liu YZ, Xiao P, Yang F, Tang ZH, Liu PY, Recker RR, Deng HW (2008) Evidence for major pleiotropic effects on bone size variation from a principal component analysis of 451 Caucasian families. Acta Pharmacol Sin 29:745\u2013751","journal-title":"Acta Pharmacol Sin"},{"key":"1236_CR46","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1073\/pnas.0711566105","volume":"105","author":"M Uda","year":"2008","unstructured":"Uda M, Galanello R, Sanna S, Lettre G, Sankaran VG, Chen W, Usala G, Busonero F, Maschio A, Albai G, Piras MG, Sestu N, Lai S, Dei M, Mulas A, Crisponi L, Naitza S, Asunis I, Deiana M, Nagaraja R, Perseu L, Satta S, Cipollina MD, Sollaino C, Moi P, Hirschhorn JN, Orkin SH, Abecasis GR, Schlessinger D, Cao A (2008) Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. Proc Natl Acad Sci USA 105:1620\u20131625","journal-title":"Proc Natl Acad Sci USA"},{"key":"1236_CR47","doi-asserted-by":"crossref","first-page":"5899","DOI":"10.1128\/MCB.21.17.5899-5912.2001","volume":"21","author":"MG Vander Heiden","year":"2001","unstructured":"Vander Heiden MG, Plas DR, Rathmell JC, Fox CJ, Harris MH, Thompson CB (2001) Growth factors can influence cell growth and survival through effects on glucose metabolism. Mol Cell Biol 21:5899\u20135912","journal-title":"Mol Cell Biol"},{"key":"1236_CR48","doi-asserted-by":"crossref","first-page":"114","DOI":"10.2133\/dmpk.24.114","volume":"24","author":"A Yamamoto","year":"2009","unstructured":"Yamamoto A, Nonen S, Fukuda T, Yamazaki H, Azuma J (2009) Genetic polymorphisms of glycine N-acyltransferase in Japanese individuals. Drug Metab Pharmacokinet 24:114\u2013117","journal-title":"Drug Metab Pharmacokinet"},{"key":"1236_CR49","doi-asserted-by":"crossref","first-page":"e6502","DOI":"10.1371\/journal.pone.0006502","volume":"4","author":"L Zhang","year":"2009","unstructured":"Zhang L, Pei YF, Li J, Papasian CJ, Deng HW (2009) Univariate\/multivariate genome-wide association scans using data from families and unrelated samples. PLoS One 4:e6502","journal-title":"PLoS One"}],"container-title":["Human Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00439-012-1236-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00439-012-1236-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00439-012-1236-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,5]],"date-time":"2019-07-05T02:22:49Z","timestamp":1562293369000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00439-012-1236-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,30]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["1236"],"URL":"https:\/\/doi.org\/10.1007\/s00439-012-1236-5","relation":{},"ISSN":["0340-6717","1432-1203"],"issn-type":[{"value":"0340-6717","type":"print"},{"value":"1432-1203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,30]]}}}