{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T23:36:30Z","timestamp":1790724990308,"version":"4.1.0"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T00:00:00Z","timestamp":1722902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T00:00:00Z","timestamp":1722902400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"DST-INSPIRE","award":["IF190194"],"award-info":[{"award-number":["IF190194"]}]},{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","award":["5\/9\/1222\/2019-Nut"],"award-info":[{"award-number":["5\/9\/1222\/2019-Nut"]}],"id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008762","name":"Tamil Nadu State Council for Higher Education","doi-asserted-by":"publisher","award":["RGP\/2019-20\/BU\/HECP-0014"],"award-info":[{"award-number":["RGP\/2019-20\/BU\/HECP-0014"]}],"id":[{"id":"10.13039\/501100008762","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Hum. Genet."],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1007\/s00439-024-02690-1","type":"journal-article","created":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T19:02:08Z","timestamp":1722970928000},"page":"15-30","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["T1R2\/T1R3 polymorphism affects sweet and fat perception: Correlation between SNP and BMI in the context of obesity development"],"prefix":"10.1007","volume":"144","author":[{"given":"Vinithra","family":"Ponnusamy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gowtham","family":"Subramanian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keerthana","family":"Vasanthakumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karthi","family":"Muthuswamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabha","family":"Panneerselvan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasanth","family":"Krishnan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selvakumar","family":"Subramaniam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,6]]},"reference":[{"key":"2690_CR2","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1093\/chemse\/bjz010","volume":"44","author":"GK Aji","year":"2019","unstructured":"Aji GK, Warren FJ, Roura E (2019) Salivary \u03b1-amylase activity and starch-related sweet taste perception in humans. Chem Senses 44:249\u2013256. https:\/\/doi.org\/10.1093\/chemse\/bjz010","journal-title":"Chem Senses"},{"key":"2690_CR3","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0264692","volume":"17","author":"N Al-Akl","year":"2022","unstructured":"Al-Akl N, Thompson RI, Arredouani A (2022) Elevated levels of salivary \u03b1- amylase activity in saliva associated with reduced odds of obesity in adult Qatari citizens: a cross-sectional study. PLoS ONE 17:e0264692. https:\/\/doi.org\/10.1371\/journal.pone.0264692","journal-title":"PLoS ONE"},{"key":"2690_CR4","doi-asserted-by":"publisher","DOI":"10.1017\/jns.2020.18","volume":"9","author":"H Bajit","year":"2020","unstructured":"Bajit H, Ait Si Mohammed O, Guennoun Y, Benaich S, Bouaiti E, Belghiti H, Mrabet M, Elfahime EM, El Haloui NE, Saeid N, El Kari K, Hichami A, Khan NA, Benkirane H, Aguenaou H (2020) Single-nucleotide polymorphism rs1761667 in the CD36 gene is associated with orosensory perception of a fatty acid in obese and normal-weight Moroccan subjects. J Nutr Sci 9:e24. https:\/\/doi.org\/10.1017\/jns.2020.18","journal-title":"J Nutr Sci"},{"key":"2690_CR5","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.3390\/nu10101539","volume":"10","author":"R Barrag\u00e1n","year":"2018","unstructured":"Barrag\u00e1n R, Coltell O, Portol\u00e9s O, Asensio EM, Sorl\u00ed JV, Ortega-Azor\u00edn C, Gonz\u00e1lez JI, S\u00e1iz C, Fern\u00e1ndez-Carri\u00f3n R, Ordovas JM, Corella D (2018) Bitter, sweet, salty, sour and umami taste perception decreases with age: sex-specific analysis, modulation by genetic variants and taste-preference associations in 18 to 80 year-old subjects. Nutrients 10:1539. https:\/\/doi.org\/10.3390\/nu10101539","journal-title":"Nutrients"},{"key":"2690_CR6","doi-asserted-by":"publisher","first-page":"555","DOI":"10.3390\/nu14030555","volume":"14","author":"L Brondel","year":"2022","unstructured":"Brondel L, Quilliot D, Mouillot T, Khan NA, Bastable P, Boggio V, Leloup C, P\u00e9nicaud L (2022) Taste of fat and obesity: different hypotheses and our point of view. Nutrients 14:555. https:\/\/doi.org\/10.3390\/nu14030555","journal-title":"Nutrients"},{"key":"2690_CR7","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1111\/1750-3841.14115","volume":"83","author":"B Burgess","year":"2018","unstructured":"Burgess B, Melis M, Scoular K, Driver M, Schaich KM, Keller KL, Tomassini Barbarossa I, Tepper BJ (2018) Effects of CD36 genotype on oral perception of oleic acid supplemented safflower oil emulsions in two ethnic groups: a preliminary study. J Food Sci 83:1373\u20131380. https:\/\/doi.org\/10.1111\/1750-3841.14115","journal-title":"J Food Sci"},{"key":"2690_CR8","doi-asserted-by":"publisher","first-page":"153","DOI":"10.3390\/nu10020153","volume":"10","author":"E Chamoun","year":"2018","unstructured":"Chamoun E, Hutchinson JM, Krystia O, Mirotta JA, Mutch DM, Buchholz AC, Duncan AM, Darlington G, Haines J, Ma DWL, Guelph Family Health S (2018) Single nucleotide polymorphisms in taste receptor genes are associated with snacking patterns of preschool-aged children in the Guelph family health study: a pilot study. Nutrients 10:153. https:\/\/doi.org\/10.3390\/nu10020153","journal-title":"Nutrients"},{"key":"2690_CR9","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.nutres.2020.12.007","volume":"85","author":"E Chamoun","year":"2021","unstructured":"Chamoun E, Liu AS, Duizer LM, Feng Z, Darlington G, Duncan AM, Haines J, Ma DWL (2021) Single nucleotide polymorphisms in sweet, fat, umami, salt, bitter and sour taste receptor genes are associated with gustatory function and taste preferences in young adults. Nutr Res 85:40\u201346. https:\/\/doi.org\/10.1016\/j.nutres.2020.12.007","journal-title":"Nutr Res"},{"key":"2690_CR10","doi-asserted-by":"publisher","first-page":"2016","DOI":"10.1093\/jn\/nxaa136","volume":"150","author":"A Chmurzynska","year":"2020","unstructured":"Chmurzynska A, Mlodzik-Czyzewska MA, Galinski G, Malinowska AM, Radziejewska A, Miko\u0142ajczyk-Stecyna J, Bulczak E, Wiebe DJ (2020) Polymorphism of CD36 determines fat discrimination but not intake of high-fat food in 20- to 40-year-old adults. J Nutr 150:2016\u20132022. https:\/\/doi.org\/10.1093\/jn\/nxaa136","journal-title":"J Nutr"},{"key":"2690_CR11","doi-asserted-by":"publisher","DOI":"10.1016\/j.appet.2021.105270","volume":"164","author":"J Di\u00f3szegi","year":"2021","unstructured":"Di\u00f3szegi J, Mohammad Kurshed AA, Pik\u00f3 P, K\u00f3sa Z, S\u00e1ndor J, \u00c1d\u00e1ny R (2021) Association of single nucleotide polymorphisms with taste and food preferences of the Hungarian general and Roma populations. Appetite 164:105270. https:\/\/doi.org\/10.1016\/j.appet.2021.105270","journal-title":"Appetite"},{"key":"2690_CR12","doi-asserted-by":"publisher","first-page":"1501","DOI":"10.3945\/ajcn.2010.29836","volume":"92","author":"KM Eny","year":"2010","unstructured":"Eny KM, Wolever TM, Corey PN, El-Sohemy A (2010) Genetic variation in TAS1R2 (Ile191Val) is associated with consumption of sugars in overweight and obese individuals in 2 distinct populations. Am J Clin Nutr 92:1501\u20131510. https:\/\/doi.org\/10.3945\/ajcn.2010.29836","journal-title":"Am J Clin Nutr"},{"key":"2690_CR13","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1017\/S0007114519000679","volume":"121","author":"R Fujii","year":"2019","unstructured":"Fujii R, Hishida A, Suzuki K, Imaeda N, Goto C, Hamajima N, Wakai K, Kondo T (2019) Cluster of differentiation 36 gene polymorphism (rs1761667) is associated with dietary MUFA intake and hypertension in a Japanese population. Br J Nutr 121:1215\u20131222","journal-title":"Br J Nutr"},{"key":"2690_CR14","doi-asserted-by":"publisher","first-page":"1288","DOI":"10.1016\/j.cub.2009.06.015","volume":"19","author":"AA Fushan","year":"2009","unstructured":"Fushan AA, Simons CT, Slack JP, Manichaikul A, Drayna D (2009) Allelic polymorphism within the TAS1R3 promoter is associated with human taste sensitivity to sucrose. Curr Biol CB 19:1288\u20131293. https:\/\/doi.org\/10.1016\/j.cub.2009.06.015","journal-title":"Curr Biol CB"},{"key":"2690_CR15","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1093\/chemse\/bjr069","volume":"37","author":"MM Galindo","year":"2012","unstructured":"Galindo MM, Voigt N, Stein J, van Lengerich J, Raguse J-D, Hofmann T, Meyerhof W, Behrens M (2012) G protein-coupled receptors in human fat taste perception. Chem Senses 37:123\u2013139. https:\/\/doi.org\/10.1093\/chemse\/bjr069","journal-title":"Chem Senses"},{"key":"2690_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodqual.2021.104202","volume":"92","author":"CAM Graham","year":"2021","unstructured":"Graham CAM, Pilic L, King A, Nixon JE, Pipe J, Holton J, Tamba K, Hearne G, Pedlar CR, Lorente-Cebri\u00e1n S, Gonz\u00e1lez Muniesa P, Mavrommatis Y (2021) Genetic differences in fat taste sensitivity and dietary intake in a UK female cohort. Food Qual Prefer 92:104202. https:\/\/doi.org\/10.1016\/j.foodqual.2021.104202","journal-title":"Food Qual Prefer"},{"key":"2690_CR17","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1017\/S0007114517002872","volume":"118","author":"P Han","year":"2017","unstructured":"Han P, Keast RSJ, Roura E (2017) Salivary leptin and TAS1R2\/TAS1R3 polymorphisms are related to sweet taste sensitivity and carbohydrate intake from a buffet meal in healthy young adults. Br J Nutr 118:763\u2013770. https:\/\/doi.org\/10.1017\/S0007114517002872","journal-title":"Br J Nutr"},{"key":"2690_CR18","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/s40795-024-00828-y","volume":"10","author":"J Hejazi","year":"2024","unstructured":"Hejazi J, Amiri R, Nozarian S, Tavasolian R, Rahimlou M (2024) Genetic determinants of food preferences: a systematic review of observational studies. BMC Nutr 10:24. https:\/\/doi.org\/10.1186\/s40795-024-00828-y","journal-title":"BMC Nutr"},{"key":"2690_CR19","doi-asserted-by":"publisher","first-page":"2707","DOI":"10.1016\/j.clnu.2021.02.044","volume":"40","author":"M Karthi","year":"2021","unstructured":"Karthi M, Deepankumar S, Vinithra P, Gowtham S, Vasanth K, Praveen Raj P, Senthilkumar R, Selvakumar S (2021) Single nucleotide polymorphism in CD36: Correlation to peptide YY levels in obese and non-obese adults. Clin Nutr (edinburgh, Scotland) 40:2707\u20132715. https:\/\/doi.org\/10.1016\/j.clnu.2021.02.044","journal-title":"Clin Nutr (edinburgh, Scotland)"},{"key":"2690_CR20","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.cobeha.2015.12.003","volume":"9","author":"RSJ Keast","year":"2016","unstructured":"Keast RSJ (2016) Effects of sugar and fat consumption on sweet and fat taste. Curr Opin Behav Sci 9:55\u201360. https:\/\/doi.org\/10.1016\/j.cobeha.2015.12.003","journal-title":"Curr Opin Behav Sci"},{"key":"2690_CR21","doi-asserted-by":"publisher","first-page":"555","DOI":"10.3390\/nu15030555","volume":"15","author":"B Kim","year":"2023","unstructured":"Kim B, Kim G, Lee Y, Taniguchi K, Isobe T, Oh S (2023) Triglyceride-glucose index as a potential indicator of sarcopenic obesity in older people. Nutrients 15:555. https:\/\/doi.org\/10.3390\/nu15030555","journal-title":"Nutrients"},{"key":"2690_CR22","doi-asserted-by":"publisher","first-page":"1595","DOI":"10.1007\/s00394-021-02758-y","volume":"61","author":"KM Livingstone","year":"2022","unstructured":"Livingstone KM, Sexton-Dhamu MJ, Pendergast FJ, Worsley A, Brayner B, McNaughton SA (2022) Energy-dense dietary patterns high in free sugars and saturated fat and associations with obesity in young adults. Eur J Nutr 61:1595\u20131607. https:\/\/doi.org\/10.1007\/s00394-021-02758-y","journal-title":"Eur J Nutr"},{"key":"2690_CR23","doi-asserted-by":"publisher","first-page":"112660","DOI":"10.1016\/j.foodres.2023.112660","volume":"167","author":"PC L\u00f3pez-D\u00e1valos","year":"2023","unstructured":"L\u00f3pez-D\u00e1valos PC, Requena T, Pozo-Bay\u00f3n M\u00c1, Mu\u00f1oz-Gonz\u00e1lez C (2023) Decreased retronasal olfaction and taste perception in obesity are related to saliva biochemical and microbiota composition. Food Res Int (ottawa, Ont) 167:112660. https:\/\/doi.org\/10.1016\/j.foodres.2023.112660","journal-title":"Food Res Int (ottawa, Ont)"},{"key":"2690_CR24","doi-asserted-by":"publisher","first-page":"4903","DOI":"10.3390\/nu14224903","volume":"14","author":"M Melis","year":"2022","unstructured":"Melis M, Mastinu M, Naciri LC, Muroni P, Tomassini Barbarossa I (2022) Associations between sweet taste sensitivity and polymorphisms (SNPs) in the TAS1R2 and TAS1R3 genes, gender, PROP taster status, and density of fungiform papillae in a genetically homogeneous Sardinian cohort. Nutrients 14:4903. https:\/\/doi.org\/10.3390\/nu14224903","journal-title":"Nutrients"},{"key":"2690_CR25","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1016\/j.foodres.2014.10.008","volume":"66","author":"I Mennella","year":"2014","unstructured":"Mennella I, Fogliano V, Vitaglione P (2014) Salivary lipase and \u03b1-amylase activities are higher in overweight than in normal weight subjects: Influences on dietary behavior. Food Res Int 66:463\u2013468. https:\/\/doi.org\/10.1016\/j.foodres.2014.10.008","journal-title":"Food Res Int"},{"key":"2690_CR26","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1111\/nbu.12633","volume":"48","author":"K Muthuswamy","year":"2023","unstructured":"Muthuswamy K, Shanmugamprema D, Subramanian G, Ponnusamy V, Vasanthakumar K, Krishnan V, Palanivelu PR, Rajasekaran S, Subramaniam S (2023) CD36 genetic polymorphism and salivary cues are associated with oleic acid sensitivity and dietary fat intake. Nutr Bull 48:376\u2013389. https:\/\/doi.org\/10.1111\/nbu.12633","journal-title":"Nutr Bull"},{"key":"2690_CR27","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1024\/0300-9831\/a000771","volume":"15","author":"D Navarro-Rios","year":"2022","unstructured":"Navarro-Rios D, Panduro A, Roman S, Ramos-Lopez O (2022) CD36 polymorphism, sugary drinks, and sedentarism are associated with hypertriglyceridemic waist phenotype. International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift Fur Vitamin- Und Ernahrungsforschung. J Int Vitaminolog De Nutr 15:10. https:\/\/doi.org\/10.1024\/0300-9831\/a000771","journal-title":"J Int Vitaminolog De Nutr"},{"key":"2690_CR28","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/s0092-8674(01)00451-2","volume":"106","author":"G Nelson","year":"2001","unstructured":"Nelson G, Hoon MA, Chandrashekar J, Zhang Y, Ryba NJ, Zuker CS (2001) Mammalian sweet taste receptors. Cell 106:381\u2013390. https:\/\/doi.org\/10.1016\/s0092-8674(01)00451-2","journal-title":"Cell"},{"key":"2690_CR29","doi-asserted-by":"crossref","unstructured":"N\u00fa\u00f1ez Salces ME (2020) The nutrient-sensing mechanisms of the mouse stomach and the ghrelin cell in health and obesity. PhD Thesis","DOI":"10.1111\/nmo.13944"},{"key":"2690_CR30","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1053\/j.gastro.2014.01.006","volume":"146","author":"MH Ozdener","year":"2014","unstructured":"Ozdener MH, Subramaniam S, Sundaresan S, Sery O, Hashimoto T, Asakawa Y, Besnard P, Abumrad NA, Khan NA (2014) CD36- and GPR120-mediated Ca2+ signaling in human taste bud cells mediates differential responses to fatty acids and is altered in obese mice. Gastroenterology 146:995\u20131005. https:\/\/doi.org\/10.1053\/j.gastro.2014.01.006","journal-title":"Gastroenterology"},{"key":"2690_CR31","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.ejphar.2004.03.004","volume":"489","author":"M Ozeck","year":"2004","unstructured":"Ozeck M, Brust P, Xu H, Servant G (2004) Receptors for bitter, sweet and umami taste couple to inhibitory G protein signaling pathways. Eur J Pharmacol 489:139\u2013149. https:\/\/doi.org\/10.1016\/j.ejphar.2004.03.004","journal-title":"Eur J Pharmacol"},{"key":"2690_CR32","doi-asserted-by":"publisher","first-page":"1242","DOI":"10.1016\/j.physbeh.2012.01.001","volume":"105","author":"LM Panek-Scarborough","year":"2012","unstructured":"Panek-Scarborough LM, Dewey AM, Temple JL (2012) Sensation and perception of sucrose and fat stimuli predict the reinforcing value of food. Physiol Behav 105:1242\u20131249. https:\/\/doi.org\/10.1016\/j.physbeh.2012.01.001","journal-title":"Physiol Behav"},{"key":"2690_CR33","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1194\/jlr.M021873","volume":"53","author":"MY Pepino","year":"2012","unstructured":"Pepino MY, Love-Gregory L, Klein S, Abumrad NA (2012) The fatty acid translocase gene CD36 and lingual lipase influence oral sensitivity to fat in obese subjects. J Lipid Res 53:561\u2013566. https:\/\/doi.org\/10.1194\/jlr.M021873","journal-title":"J Lipid Res"},{"key":"2690_CR34","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1159\/000455915","volume":"9","author":"MB Pioltine","year":"2016","unstructured":"Pioltine MB, de Melo ME, Santos A, Machado AD, Fernandes AE, Fujiwara CT, Cercato C, Mancini MC (2016) Genetic variation in CD36 is associated with decreased fat and sugar intake in obese children and adolescents. J Nutrigenet Nutrigenom 9:300\u2013305. https:\/\/doi.org\/10.1159\/000455915","journal-title":"J Nutrigenet Nutrigenom"},{"key":"2690_CR35","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3390\/jpm8010007","volume":"8","author":"MB Pioltine","year":"2018","unstructured":"Pioltine MB, de Melo ME, Santos AS, Machado AD, Fernandes AE, Fujiwara CT, Cercato C, Mancini MC (2018) Genetic variations in sweet taste receptor gene are related to chocolate powder and dietary fiber intake in obese children and adolescents. J Pers Med 8:7. https:\/\/doi.org\/10.3390\/jpm8010007","journal-title":"J Pers Med"},{"key":"2690_CR36","doi-asserted-by":"publisher","DOI":"10.1111\/obr.13512","volume":"23","author":"V Ponnusamy","year":"2022","unstructured":"Ponnusamy V, Subramanian G, Muthuswamy K, Shanmugamprema D, Krishnan V, Velusamy T, Subramaniam S (2022) Genetic variation in sweet taste receptors and a mechanistic perspective on sweet and fat taste sensation in the context of obesity. Obes Rev 23:e13512. https:\/\/doi.org\/10.1111\/obr.13512","journal-title":"Obes Rev"},{"key":"2690_CR37","doi-asserted-by":"publisher","first-page":"112294","DOI":"10.1016\/j.foodres.2022.112294","volume":"163","author":"V Ponnusamy","year":"2023","unstructured":"Ponnusamy V, Subramanian G, Muthuswamy K, Shanmugamprema D, Vasanthakumar K, Krishnan V, Subramaniam S (2023) Tongue papillae density and fat taster status- a cardinal role on sweet and bitter taste perception among Indian population. Food Res Int (ottawa, Ont.) 163:112294. https:\/\/doi.org\/10.1016\/j.foodres.2022.112294","journal-title":"Food Res Int (ottawa, Ont.)"},{"key":"2690_CR38","doi-asserted-by":"publisher","first-page":"fasebj.2022.36.","DOI":"10.1096\/fasebj.2022.36.S1.R2184","volume":"36","author":"S Primeaux","year":"2022","unstructured":"Primeaux S, Weir A, Denstel K, Martin CK, Hsia D, Staiano A (2022) Role of taste receptor gene variations (SNPs) on diet quality in adolescent females. FASEB J 36:fasebj.2022.36.S1.R2184. https:\/\/doi.org\/10.1096\/fasebj.2022.36.S1.R2184","journal-title":"FASEB J"},{"key":"2690_CR39","doi-asserted-by":"publisher","first-page":"101","DOI":"10.3390\/nu8020101","volume":"8","author":"O Ramos-Lopez","year":"2016","unstructured":"Ramos-Lopez O, Panduro A, Martinez-Lopez E, Roman S (2016) Sweet taste receptor TAS1R2 polymorphism (Val191Val) is associated with a higher carbohydrate intake and hypertriglyceridemia among the population of West Mexico. Nutrients 8:101. https:\/\/doi.org\/10.3390\/nu8020101","journal-title":"Nutrients"},{"key":"2690_CR40","doi-asserted-by":"publisher","first-page":"1389208","DOI":"10.1080\/16546628.2017.1389208","volume":"61","author":"L Rodrigues","year":"2017","unstructured":"Rodrigues L, Costa G, Cordeiro C, Pinheiro C, Amado F, Lamy E (2017) Salivary proteome and glucose levels are related with sweet taste sensitivity in young adults. Food Nutr Res 61:1389208. https:\/\/doi.org\/10.1080\/16546628.2017.1389208","journal-title":"Food Nutr Res"},{"key":"2690_CR41","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1016\/j.archoralbio.2015.02.015","volume":"60","author":"L Rodrigues","year":"2015","unstructured":"Rodrigues L, Mouta R, Costa AR, Pereira A, Capela e Silva F, Amado F, Antunes CM, Lamy E (2015) Effects of high-fat diet on salivary \u03b1-amylase, serum parameters and food consumption in rats. Arch Oral Biol 60:854\u2013862. https:\/\/doi.org\/10.1016\/j.archoralbio.2015.02.015","journal-title":"Arch Oral Biol"},{"key":"2690_CR42","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1016\/j.jare.2020.05.020","volume":"24","author":"M Saber-Ayad","year":"2020","unstructured":"Saber-Ayad M, Hammoudeh S, Radwan H, Manzoor S, Jabbar H, Wardeh R, Ashraf A, Habib P, Alsamman AM, Hamoudi R (2020) The FGF-21 genetic variants rs838133 and rs838145 are associated with high salt intake in the Emirati population. J Adv Res 24:485\u2013494. https:\/\/doi.org\/10.1016\/j.jare.2020.05.020","journal-title":"J Adv Res"},{"key":"2690_CR43","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2021.101339","volume":"54","author":"J Serrano","year":"2021","unstructured":"Serrano J, Seflova J, Park J, Pribadi M, Sanematsu K, Shigemura N, Serna V, Yi F, Mari A, Procko E, Pratley RE, Robia SL, Kyriazis GA (2021) The Ile191Val is a partial loss-of-function variant of the TAS1R2 sweet-taste receptor and is associated with reduced glucose excursions in humans. Mol Metab 54:101339. https:\/\/doi.org\/10.1016\/j.molmet.2021.101339","journal-title":"Mol Metab"},{"key":"2690_CR44","doi-asserted-by":"publisher","first-page":"3489","DOI":"10.1096\/fj.201600422R","volume":"30","author":"S Subramaniam","year":"2016","unstructured":"Subramaniam S, Ozdener MH, Abdoul-Azize S, Saito K, Malik B, Maquart G, Hashimoto T, Marambaud P, Aribi M, Tordoff MG, Besnard P, Khan NA (2016) ERK1\/2 activation in human taste bud cells regulates fatty acid signaling and gustatory perception of fat in mice and humans. FASEB J 30:3489\u20133500. https:\/\/doi.org\/10.1096\/fj.201600422R","journal-title":"FASEB J"},{"key":"2690_CR45","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1093\/chemse\/bjx054","volume":"42","author":"U Walliczek-Dworschak","year":"2017","unstructured":"Walliczek-Dworschak U, Sch\u00f6ps F, Feron G, Brignot H, H\u00e4hner A, Hummel T (2017) Differences in the density of fungiform papillae and composition of saliva in patients with taste disorders compared to healthy controls. Chem Senses 42:699\u2013708. https:\/\/doi.org\/10.1093\/chemse\/bjx054","journal-title":"Chem Senses"},{"key":"2690_CR46","doi-asserted-by":"publisher","first-page":"1641","DOI":"10.3390\/foods12081641","volume":"12","author":"E Winzer","year":"2023","unstructured":"Winzer E, Wallner M, Aufschnaiter AL, Grach D, Lampl C, Sch\u00e4tzer M, Holstein B, Wakolbinger M (2023) Investigating the relationships between taste preferences and beverage intake in preadolescents. Foods (basel, Switzerland) 12:1641. https:\/\/doi.org\/10.3390\/foods12081641","journal-title":"Foods (basel, Switzerland)"},{"key":"2690_CR47","doi-asserted-by":"publisher","first-page":"1510","DOI":"10.1017\/S0007114523000570","volume":"130","author":"Z Yazdanpanah","year":"2023","unstructured":"Yazdanpanah Z, Salehi-Abargouei A, Mollahosseini M, Sheikhha MH, Mirzaei M, Mozaffari-Khosravi H (2023) The cluster of differentiation 36 (CD36) rs1761667 polymorphism interacts with dietary patterns to affect cardiometabolic risk factors and metabolic syndrome risk in apparently healthy individuals. Br J Nutr 130:1510\u20131520. https:\/\/doi.org\/10.1017\/S0007114523000570","journal-title":"Br J Nutr"},{"key":"2690_CR48","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1016\/j.acthis.2014.08.002","volume":"116","author":"Z-Q Zhang","year":"2014","unstructured":"Zhang Z-Q, Shu G, Zhu X-T, Wang L-N, Fu Q, Hou L-J, Wang S-B, Gao P, Xi Q-Y, Zhang Y-L, Yu L, Lv J-R, Jiang Q-Y (2014) Isolation and characterization of porcine circumvallate papillae cells. Acta Histochem 116:1313\u20131322. https:\/\/doi.org\/10.1016\/j.acthis.2014.08.002","journal-title":"Acta Histochem"}],"container-title":["Human Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00439-024-02690-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00439-024-02690-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00439-024-02690-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T06:48:40Z","timestamp":1737528520000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00439-024-02690-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,6]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["2690"],"URL":"https:\/\/doi.org\/10.1007\/s00439-024-02690-1","relation":{},"ISSN":["0340-6717","1432-1203"],"issn-type":[{"value":"0340-6717","type":"print"},{"value":"1432-1203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,6]]},"assertion":[{"value":"28 November 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 July 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 August 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose. The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Bharathiar University Human Ethics Committee (Proposal No. BUHEC-051\/2020 dated 30.01.2020).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}}]}}