{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T03:35:27Z","timestamp":1790134527912,"version":"4.0.1"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2007,1,10]],"date-time":"2007-01-10T00:00:00Z","timestamp":1168387200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Tissue Res"],"published-print":{"date-parts":[[2007,3,21]]},"DOI":"10.1007\/s00441-006-0350-x","type":"journal-article","created":{"date-parts":[[2007,1,9]],"date-time":"2007-01-09T10:05:41Z","timestamp":1168337141000},"page":"365-374","source":"Crossref","is-referenced-by-count":25,"title":["Localization of TFF3 peptide in human esophageal submucosal glands and gastric cardia: differentiation of two types of gastric pit cells along the rostro-caudal axis"],"prefix":"10.1007","volume":"328","author":[{"given":"Irina","family":"Kouznetsova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Kalinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Peitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus E.","family":"M\u00f6nkem\u00fcller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubert","family":"Kalbacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Vieth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Roessner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Malfertheiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Lippert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Werner","family":"Hoffmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2007,1,10]]},"reference":[{"key":"350_CR1","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1136\/gut.47.6.753","volume":"47","author":"GS Arul","year":"2000","unstructured":"Arul GS, Moorghen M, Myerscough N, Alderson DA, Spicer RD, Corfield AP (2000) Mucin gene expression in Barrett\u2019s oesophagus: an in situ hybridisation and immunhistochemical study. Gut 47:753\u2013761","journal-title":"Gut"},{"key":"350_CR2","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/sj.neo.7900221","volume":"4","author":"MT Barrett","year":"2002","unstructured":"Barrett MT, Yeung KY, Ruzzo WL, Hsu L, Blount PL, Sullivan R, Zarbl H, Delrow J, Rabinovitch PS, Reid BJ (2002) Transcriptional analyses of Barrett\u2019s metaplasia and normal upper GI mucosae. Neoplasia 4:121\u2013128","journal-title":"Neoplasia"},{"key":"350_CR3","doi-asserted-by":"crossref","first-page":"2947","DOI":"10.1007\/s00018-005-5483-7","volume":"62","author":"M Baus-Loncar","year":"2005","unstructured":"Baus-Loncar M, Kayademir T, Takaishi S, Wang T (2005) Trefoil factor family 2 deficiency and immune response. Cell Mol Life Sci 62:2947\u20132955","journal-title":"Cell Mol Life Sci"},{"key":"350_CR4","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/j.1365-2184.2004.00299.x","volume":"37","author":"M Brittan","year":"2004","unstructured":"Brittan M, Wright NA (2004) The gastrointestinal stem cell. Cell Prolif 37:35\u201353","journal-title":"Cell Prolif"},{"key":"350_CR5","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1126\/science.1108661","volume":"308","author":"LJ Cliffe","year":"2005","unstructured":"Cliffe LJ, Humphreys NE, Lane TE, Potten CS, Booth C, Grencis RK (2005) Accelerated intestinal epithelial cell turnover: a new mechanism of parasite expulsion. Science 308:1463\u20131465","journal-title":"Science"},{"key":"350_CR6","first-page":"461","volume-title":"Histology for pathologists","author":"FG DeNardi","year":"1997","unstructured":"DeNardi FG, Riddell RH (1997) Esophagus. In: Sternberg SS (ed) Histology for pathologists. Lippincott-Raven, Philadelphia, pp 461\u2013480"},{"key":"350_CR7","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1053\/hp.2000.6549","volume":"31","author":"DA Devine","year":"2000","unstructured":"Devine DA, High AS, Owen PJ, Poulsom R, Bonass WA (2000) Trefoil factor expression in normal and diseased human salivary glands. Hum Pathol 31:509\u2013515","journal-title":"Hum Pathol"},{"key":"350_CR8","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1097\/00000478-199610000-00001","volume":"20","author":"MF Dixon","year":"1996","unstructured":"Dixon MF, Genta RM, Yardley JH, Correa P, Participants of the International Workshop on the Histology of Gastritis (1996) Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994. Am J Surg Pathol 20:1161\u20131181","journal-title":"Am J Surg Pathol"},{"key":"350_CR9","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S1052-5157(03)00007-2","volume":"13","author":"RC Fitzgerald","year":"2003","unstructured":"Fitzgerald RC, Farthing MJG (2003) The pathogenesis of Barrett\u2019s esophagus. Gastrointest Endoscopy Clin 13:233\u2013255","journal-title":"Gastrointest Endoscopy Clin"},{"key":"350_CR10","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1593\/neo.04715","volume":"7","author":"CA Fox","year":"2005","unstructured":"Fox CA, Sapinoso LM, Zhang H, Zhang W, McLeod HL, Petroni GR, Mullick T, Moskaluk CA, Frierson HF, Hampton GM, Powell SM (2005) Altered expression of TFF-1 and CES-2 in Barrett\u2019s esophagus and associated adenocarcinomas. Neoplasia 7:407\u2013416","journal-title":"Neoplasia"},{"key":"350_CR11","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1002\/1097-0215(20001215)88:6<856::AID-IJC3>3.0.CO;2-D","volume":"88","author":"P Guillem","year":"2000","unstructured":"Guillem P, Billeret V, Buisine MP, Flejou JF, Lecomte-Houcke M, Degand P, Aubert JP, Triboulet JP, Porchet N (2000) Mucin gene expression and cell differentiation in human normal, premalignant and malignant esophagus. Int J Cancer 88:856\u2013861","journal-title":"Int J Cancer"},{"key":"350_CR12","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/0016-5085(93)90956-D","volume":"105","author":"AM Hanby","year":"1993","unstructured":"Hanby AM, Poulsom R, Singh S, Jeffery RE, Wright N (1993) Spasmolytic polypeptide is a major antral peptide: distribution of the trefoil peptides human spasmolytic polypeptide and pS2 in the stomach. Gastroenterology 105:1110\u20131116","journal-title":"Gastroenterology"},{"key":"350_CR13","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/path.1711730303","volume":"173","author":"AM Hanby","year":"1994","unstructured":"Hanby AM, Jankowski JAZ, Elia G, Poulsom R, Wright NA (1994) Expression of the trefoil peptides pS2 and human spasmolytic polypeptide (hSP) in Barrett\u2019s metaplasia and the native esophageal epithelium: delineation of epithelial phenotype. J Pathol 173:213\u2013219","journal-title":"J Pathol"},{"key":"350_CR14","doi-asserted-by":"crossref","first-page":"2932","DOI":"10.1007\/s00018-005-5481-9","volume":"62","author":"W Hoffmann","year":"2005","unstructured":"Hoffmann W (2005) TFF (trefoil factor family) peptide-triggered signals promoting mucosal restitution. Cell Mol Life Sci 62:2932\u20132938","journal-title":"Cell Mol Life Sci"},{"key":"350_CR15","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/B978-012369442-3\/50160-4","volume-title":"Handbook of biologically active peptides","author":"W Hoffmann","year":"2006","unstructured":"Hoffmann W (2006) TFF (trefoil factor family) peptides. In: Kastin AJ (ed) Handbook of biologically active peptides. Elsevier, San Diego, pp\u00a01147\u20131154"},{"key":"350_CR16","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0074-7696(02)13014-2","volume":"213","author":"W Hoffmann","year":"2002","unstructured":"Hoffmann W, Jagla W (2002) Cell type specific expression of secretory TFF-peptides: co-localization with mucins and synthesis in the brain. Int Rev Cytol 213:147\u2013181","journal-title":"Int Rev Cytol"},{"key":"350_CR17","first-page":"319","volume":"16","author":"W Hoffmann","year":"2001","unstructured":"Hoffmann W, Jagla W, Wiede A (2001) Molecular medicine of TFF-peptides: from gut to brain. Histol Histopathol 16:319\u2013334","journal-title":"Histol Histopathol"},{"key":"350_CR18","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s004410050975","volume":"291","author":"W Jagla","year":"1998","unstructured":"Jagla W, Wiede A, K\u00f6lle S, Hoffmann W (1998) Differential expression of the TFF-peptides xP1 and xP4 in the gastrointestinal tract of Xenopus laevis. Cell Tissue Res 291:13\u201318","journal-title":"Cell Tissue Res"},{"key":"350_CR19","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s004419900087","volume":"298","author":"W Jagla","year":"1999","unstructured":"Jagla W, Wiede A, Hinz M, Dietzmann K, G\u00fclicher D, Gerlach KL, Hoffmann W (1999) Secretion of TFF-peptides by human salivary glands. Cell Tissue Res 298:161\u2013166","journal-title":"Cell Tissue Res"},{"key":"350_CR20","doi-asserted-by":"crossref","first-page":"2861","DOI":"10.1093\/nar\/12.6.2861","volume":"12","author":"SB Jakowlew","year":"1984","unstructured":"Jakowlew SB, Breathnach R, Jeltsch JM, Masiakowski P, Chambon P (1984) Sequence of the pS2 mRNA induced by estrogen in the human breast cancer cell line MCF-7. Nucleic Acids Res 12:2861\u20132878","journal-title":"Nucleic Acids Res"},{"key":"350_CR21","doi-asserted-by":"crossref","first-page":"286","DOI":"10.2741\/A426","volume":"4","author":"SM Karam","year":"1999","unstructured":"Karam SM (1999) Lineage commitment and maturation of epithelial cells in the gut. Front Biosci 4:286\u2013298","journal-title":"Front Biosci"},{"key":"350_CR22","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1002\/ar.1092360203","volume":"236","author":"S Karam","year":"1993","unstructured":"Karam S, Leblond CP (1993) Dynamics of epithelial cells in the corpus of the mouse stomach. II. Outward migration of pit cells. Anat Rec 236:280\u2013296","journal-title":"Anat Rec"},{"key":"350_CR23","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/jemt.1070310304","volume":"31","author":"S Karam","year":"1995","unstructured":"Karam S, Leblond CP (1995) Origin and migratory pathways of the eleven epithelial cell types present in the body of the mouse stomach. Microsc Res Tech 31:193\u2013214","journal-title":"Microsc Res Tech"},{"key":"350_CR24","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1634\/stemcells.21-3-322","volume":"21","author":"SM Karam","year":"2003","unstructured":"Karam SM, Straiton T, Hassan WM, Leblond CP (2003) Defining epithelial cell progenitors in the human oxyntic mucosa. Stem Cells 21:322\u2013336","journal-title":"Stem Cells"},{"key":"350_CR25","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1136\/gut.2003.031963","volume":"53","author":"SM Karam","year":"2004","unstructured":"Karam SM, Tomasetto C, Rio MC (2004) Trefoil factor 1 is required for the commitment programme of mouse oxyntic epithelial progenitors. Gut 53:1408\u20131415","journal-title":"Gut"},{"key":"350_CR26","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s00441-004-0854-1","volume":"316","author":"I Kouznetsova","year":"2004","unstructured":"Kouznetsova I, Peitz U, Vieth M, Meyer F, Vestergaard EM, Malfertheiner P, Roessner A, Lippert H, Hoffmann W (2004) A gradient of TFF3 (trefoil factor family 3) peptide synthesis within the normal human gastric mucosa. Cell Tissue Res 316:155\u2013165","journal-title":"Cell Tissue Res"},{"key":"350_CR27","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s004320050244","volume":"125","author":"C Labouvie","year":"1999","unstructured":"Labouvie C, Machado JC, Carneiro F, Sarbia M, Vieth M, Porschen R, Seitz G, Blin N (1999) Differential expression of mucins and trefoil peptides in native epithelium, Barrett\u2019s metaplasia and squamous cell carcinoma of the esophagus. J Cancer Res Clin Oncol 125:71\u201376","journal-title":"J Cancer Res Clin Oncol"},{"key":"350_CR28","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1002\/aja.1001720305","volume":"172","author":"ER Lee","year":"1985","unstructured":"Lee ER (1985) Dynamic histology of the antral epithelium in the mouse stomach. III. Ultrastructure and renewal of pit cells. Am J Anat 172:225\u2013240","journal-title":"Am J Anat"},{"key":"350_CR29","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1126\/science.274.5285.262","volume":"274","author":"H Mashimo","year":"1996","unstructured":"Mashimo H, Wu DC, Podolsky DK, Fishman MC (1996) Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor. Science 274:262\u2013265","journal-title":"Science"},{"key":"350_CR30","doi-asserted-by":"crossref","first-page":"14819","DOI":"10.1073\/pnas.192574799","volume":"99","author":"JC Mills","year":"2002","unstructured":"Mills JC, Andersson N, Hong CV, Stappenbeck TS, Gordon JI (2002) Molecular characterization of mouse gastric epithelial progenitor cells. Proc Natl Acad Sci USA 99:14819\u201314824","journal-title":"Proc Natl Acad Sci USA"},{"key":"350_CR31","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1006\/bbrc.1996.1365","volume":"226","author":"S Nomura","year":"1996","unstructured":"Nomura S, Kaminishi M, Sugiyama K, Oohara T, Esumi H (1996) Clonal analysis of isolated single fundic and pyloric gland of stomach using X-linked polymorphism. Biochem Biophys Res Commun 226:385\u2013390","journal-title":"Biochem Biophys Res Commun"},{"key":"350_CR32","doi-asserted-by":"crossref","first-page":"4287","DOI":"10.1038\/sj.onc.1206615","volume":"22","author":"KA Oien","year":"2003","unstructured":"Oien KA, Vass JK, Downie I, Fullarton G, Keith WN (2003) Profiling, comparison and validation of gene expression in gastric carcinoma and normal stomach. Oncogene 22:4287\u20134300","journal-title":"Oncogene"},{"key":"350_CR33","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1136\/gut.34.7.893","volume":"34","author":"S Patel","year":"1993","unstructured":"Patel S, Rew DA, Taylor I, Potten CS, Owen C, Roberts SA (1993) Study of the proliferation in human gastric mucosa after in vivo bromodeoxyuridine labelling. Gut 34:893\u2013896","journal-title":"Gut"},{"key":"350_CR34","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.peptides.2004.01.018","volume":"25","author":"U Peitz","year":"2004","unstructured":"Peitz U, Kouznetsova I, Wex T, Gebert I, Vieth M, Roessner A, Hoffmann W, Malfertheiner P (2004) TFF3 expression at the esophagogastric junction is increased in gastro-esophageal reflux disease (GERD). Peptides 25:771\u2013777","journal-title":"Peptides"},{"key":"350_CR35","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1136\/gut.37.5.595","volume":"37","author":"RJ Playford","year":"1995","unstructured":"Playford RJ (1995) Peptides and gastrointestinal mucosal integrity. Gut 37:595\u2013597","journal-title":"Gut"},{"key":"350_CR36","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.coph.2004.05.004","volume":"4","author":"RJ Playford","year":"2004","unstructured":"Playford RJ, Ghosh S, Mahmood A (2004) Growth factors and trefoil peptides in gastrointestinal health and disease. Curr Opin Pharmacol 4:567\u2013571","journal-title":"Curr Opin Pharmacol"},{"key":"350_CR37","doi-asserted-by":"crossref","first-page":"6694","DOI":"10.1016\/S0021-9258(18)53305-6","volume":"268","author":"DK Podolsky","year":"1993","unstructured":"Podolsky DK, Lynch-Devaney K, Stow JL, Oates P, Murgue B, De-Beaumont M, Sands BE, Mahida YR (1993) Identification of human intestinal trefoil factor. Goblet cell-specific expression of a peptide targeted for apical secretion. J Biol Chem 268:6694\u20136702","journal-title":"J Biol Chem"},{"key":"350_CR38","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.regpep.2004.09.007","volume":"26","author":"SS Poulsen","year":"2005","unstructured":"Poulsen SS, Kissow H, Hare K, Hartmann B, Thim L (2005) Luminal and parenteral TFF2 and TFF3 dimer and monomer in two models of experimental colitis in the rat. Regul Pept 26:163\u2013171","journal-title":"Regul Pept"},{"key":"350_CR39","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0169-328X(95)00137-H","volume":"33","author":"JC Probst","year":"1995","unstructured":"Probst JC, Skutella T, M\u00fcller-Schmid A, Jirikowski GF, Hoffmann W (1995) Molecular and cellular analysis of rP1.B in the rat hypothalamus: in situ hybridization and immunohistochemistry of a new P-domain neuropeptide. Mol Brain Res 33:269\u2013276","journal-title":"Mol Brain Res"},{"key":"350_CR40","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1126\/science.3041593","volume":"241","author":"MC Rio","year":"1988","unstructured":"Rio MC, Bellocq JP, Daniel JY, Tomasetto C, Lathe R, Chenard MP, Batzenschlager A, Chambon P (1988) Breast cancer-associated pS2 protein: synthesis and secretion by normal stomach mucosa. Science 241:705\u2013708","journal-title":"Science"},{"key":"350_CR41","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1111\/j.1572-0241.2002.05910.x","volume":"97","author":"RE Sampliner","year":"2002","unstructured":"Sampliner RE (2002) Updated guidelines for the diagnosis, surveillance, and therapy of Barrett\u2019s esophagus. Am J Gastroenterol 97:1888\u20131895","journal-title":"Am J Gastroenterol"},{"key":"350_CR42","first-page":"701","volume":"14","author":"J Sarosiek","year":"2000","unstructured":"Sarosiek J, McCallum RW (2000) Mechanisms of oesophageal mucosal defence. Bailli\u00e8re\u2019s Clin Gastroenterol 14:701\u2013717","journal-title":"Clin Gastroenterol"},{"key":"350_CR43","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1038\/nrm1203","volume":"4","author":"D Taupin","year":"2003","unstructured":"Taupin D, Podolsky DK (2003) Trefoil factors: initiators of mucosal healing. Nat Rev 4:721\u2013733","journal-title":"Nat Rev"},{"key":"350_CR44","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1053\/j.gastro.2005.07.026","volume":"129","author":"JWPM Baal van","year":"2005","unstructured":"van Baal JWPM, Milano F, Baal Rygiel AM, Bergman JJGHM, Rosmolen WD, Deventer SJH van, Wang KK, Peppelenbosch MP, Krishnadath KK (2005) A comparative analysis by SAGE of gene expression profiles of Barrett\u2019s esophagus, normal squamous esophagus, and gastric cardia. Gastroenterology 129:1274\u20131281","journal-title":"Gastroenterology"},{"key":"350_CR45","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1046\/j.1365-2559.2003.01619.x","volume":"42","author":"JHB Bovenkamp Van de","year":"2003","unstructured":"Van de Bovenkamp JHB, Korteland-Van Male AM, Warson C, B\u00fcller HA, Einerhand AWC, Ectors NLEY, Dekker J (2003) Gastric-type mucin and TFF-peptide expression in Barrett\u2019s oesophagus is disturbed during increased expression of MUC2. Histopathol 42:555\u2013565","journal-title":"Histopathol"},{"key":"350_CR46","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1053\/j.gastro.2004.05.020","volume":"127","author":"K Vandenbroucke","year":"2004","unstructured":"Vandenbroucke K, Hans W, Huysse J van, Neirynck S, Demetter P, Remaut E, Rottiers P, Steidler L (2004) Active delivery of trefoil factors by genetically modified Lactococcus lactis prevents and heals acute colitis in mice. Gastroenterology 127:502\u2013513","journal-title":"Gastroenterology"},{"key":"350_CR47","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1038\/nature01440","volume":"422","author":"PD Vermeer","year":"2003","unstructured":"Vermeer PD, Einwalter LA, Moninger TO, Rokhlina T, Kern JA, Zabner J, Welsh MJ (2003) Segregation of receptor and ligand regulates activation of epithelial growth factor receptor. Nature 422:322\u2013326","journal-title":"Nature"},{"key":"350_CR48","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1002\/(SICI)1097-0029(20000301)48:5<303::AID-JEMT7>3.0.CO;2-X","volume":"48","author":"A Herbay Von","year":"2000","unstructured":"Von Herbay A, Rudi J (2000) Role of apoptosis in gastric epithelial turnover. Microsc Res Tech 48:303\u2013311","journal-title":"Microsc Res Tech"},{"key":"350_CR49","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1038\/nm1002-1080","volume":"8","author":"TC Wang","year":"2002","unstructured":"Wang TC, Goldenring JR (2002) Inflammation intersection: gp130 balances gut irritation and stomach cancer. Nat Med 8:1080\u20131082","journal-title":"Nat Med"},{"key":"350_CR50","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1053\/hupa.2002.124907","volume":"33","author":"C Warson","year":"2002","unstructured":"Warson C, Van de Bovenkamp JHB, Korteland-van Male AM, B\u00fcller HA, Einerhand AWC, Ectors NLEY, Dekker J (2002) Barrett\u2019s esophagus is characterized by expression of gastric-type mucins (MUC5AC, MUC6) and TFF peptides (TFF1 and TFF2), but the risk of carcinoma development may be indicated by the intestinal-type mucin, MUC2. Hum Pathol 33:660\u2013668","journal-title":"Hum Pathol"},{"key":"350_CR51","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1164\/ajrccm.159.4.9804149","volume":"159","author":"A Wiede","year":"1999","unstructured":"Wiede A, Jagla W, Welte T, K\u00f6hnlein T, Busk H, Hoffmann W (1999) Localization of TFF3, a new mucus-associated peptide of the human respiratory tract. Am J Respir Crit Care Med 159:1330\u20131335","journal-title":"Am J Respir Crit Care Med"},{"key":"350_CR52","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1136\/gut.44.6.890","volume":"44","author":"WM Wong","year":"1999","unstructured":"Wong WM, Poulsom R, Wright NA (1999) Trefoil peptides. Gut 44:890\u2013895","journal-title":"Gut"},{"key":"350_CR53","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1046\/j.1365-2613.2000.00146.x","volume":"81","author":"NA Wright","year":"2000","unstructured":"Wright NA (2000) Epithelial stem cell repertoire in the gut: clues to the origin of cell lineages, proliferative units and cancer. Int J Exp Path 81:117\u2013143","journal-title":"Int J Exp Path"}],"container-title":["Cell and Tissue Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00441-006-0350-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00441-006-0350-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00441-006-0350-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,7]],"date-time":"2021-08-07T11:42:40Z","timestamp":1628336560000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00441-006-0350-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1,10]]},"references-count":53,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,3,21]]}},"alternative-id":["350"],"URL":"https:\/\/doi.org\/10.1007\/s00441-006-0350-x","relation":{},"ISSN":["0302-766X","1432-0878"],"issn-type":[{"value":"0302-766X","type":"print"},{"value":"1432-0878","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,1,10]]}}}