{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T10:26:45Z","timestamp":1788863205876,"version":"build-2803163510"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2010,4,30]],"date-time":"2010-04-30T00:00:00Z","timestamp":1272585600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Tissue Res"],"published-print":{"date-parts":[[2010,6]]},"DOI":"10.1007\/s00441-010-0957-9","type":"journal-article","created":{"date-parts":[[2010,4,29]],"date-time":"2010-04-29T03:07:06Z","timestamp":1272510426000},"page":"427-436","source":"Crossref","is-referenced-by-count":30,"title":["C-kit-immunopositive interstitial cells of Cajal in human embryonal and fetal oesophagus"],"prefix":"10.1007","volume":"340","author":[{"given":"Goran","family":"Radenkovic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Ilic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dragoljub","family":"Zivanovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Slobodan","family":"Vlajkovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir","family":"Petrovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivera","family":"Mitrovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,4,30]]},"reference":[{"key":"957_CR1","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1113\/jphysiol.2003.050419","volume":"553","author":"EAH Beckett","year":"2003","unstructured":"Beckett EAH, McGeough CA, Sanders KM, Ward SM (2003) Pacing of interstitial cells of Cajal in the murine gastric antrum: neurally mediated and direct stimulation. J Physiol (Lond) 553:545\u2013559","journal-title":"J Physiol (Lond)"},{"key":"957_CR2","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/cne.20746","volume":"493","author":"EAH Beckett","year":"2005","unstructured":"Beckett EAH, Takeda Y, Yanase H, Sanders KM, Ward SM (2005) Synaptic specializations exist between enteric motor nerves and interstitial cells of Cajal in the murine stomach. J Comp Neurol 493:193\u2013206","journal-title":"J Comp Neurol"},{"key":"957_CR3","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s00441-001-0474-y","volume":"307","author":"V Belzer","year":"2002","unstructured":"Belzer V, Kobilo T, Rich A, Hanani M (2002) Intercellular coupling among interstitial cells of Cajal in the guinea pig small intestine. Cell Tissue Res 307:15\u201321","journal-title":"Cell Tissue Res"},{"key":"957_CR4","doi-asserted-by":"crossref","first-page":"G517","DOI":"10.1152\/ajpgi.1989.257.4.G517","volume":"257","author":"EL Blank","year":"1989","unstructured":"Blank EL, Greenwood B, Dodds WJ (1989) Cholinergic control of smooth muscle peristalsis in the cat esophagus. Am J Physiol Gastrointest Liver Physiol 257:G517\u2013G523","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"957_CR5","doi-asserted-by":"crossref","first-page":"12008","DOI":"10.1073\/pnas.93.21.12008","volume":"93","author":"AJ Burns","year":"1996","unstructured":"Burns AJ, Lomax AEJ, Torihashi S, Sanders KM, Ward SM (1996) Interstitial cells of Cajal mediate inhibitory neurotransmission in the stomach. Proc Nat Acad Sci USA 93:12008\u201312013","journal-title":"Proc Nat Acad Sci USA"},{"key":"957_CR6","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s004410050902","volume":"290","author":"AJ Burns","year":"1997","unstructured":"Burns AJ, Herbert TM, Ward SM, Sanders KM (1997) Interstitial cells of Cajal in the guinea-pig gastrointestinal tract as revealed by c-Kit immunohistochemistry. Cell Tissue Res 290:11\u201320","journal-title":"Cell Tissue Res"},{"key":"957_CR7","doi-asserted-by":"crossref","first-page":"40S","DOI":"10.1016\/S0002-9343(97)00320-3","volume":"103","author":"NE Diamant","year":"1997","unstructured":"Diamant NE (1997) Neuromuscular mechanisms of primary peristalsis. Am J Med 103:40S\u201343S","journal-title":"Am J Med"},{"key":"957_CR8","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1111\/j.1365-2982.2007.00901.x","volume":"19","author":"R Farre","year":"2007","unstructured":"Farre R, Wang XY, Vidal E, Domenech A, Pumarola M, Clave P, Huizinga JD, Jimenez M (2007) Interstitial cells of Cajal and neuromuscular transmission in the rat lower oesophageal sphincter. Neurogastroenterol Motil 19:484\u2013496","journal-title":"Neurogastroenterol Motil"},{"key":"957_CR9","first-page":"673","volume":"17","author":"MS Faussone-Pellegrini","year":"1985","unstructured":"Faussone-Pellegrini MS, Cortesini C (1985a) The muscle coat of the lower esophageal sphincter in patients with achalasia and hypertensive sphincter. An electron microscopic study. J Submicrosc Cytol 17:673\u2013685","journal-title":"J Submicrosc Cytol"},{"key":"957_CR10","first-page":"187","volume":"17","author":"MS Faussone-Pellegrini","year":"1985","unstructured":"Faussone-Pellegrini MS, Cortesini C (1985b) Ultrastructural features and localization of the interstitial cells of Cajal in the smooth muscle coat of human esophagus. J Submicrosc Cytol 17:187\u2013197","journal-title":"J Submicrosc Cytol"},{"key":"957_CR11","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1111\/j.1582-4934.2007.00043.x","volume":"11","author":"MS Faussone-Pellegrini","year":"2007","unstructured":"Faussone-Pellegrini MS, Vannucchi MG, Alaggio R, Strojna A, Midrio P (2007) Morphology of the interstitial cells of Cajal of the human ileum from foetal to neonatal life. J Cell Mol Med 11:482\u2013494","journal-title":"J Cell Mol Med"},{"key":"957_CR12","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/s00429-002-0261-x","volume":"205","author":"EA Fox","year":"2002","unstructured":"Fox EA, Phillips RJ, Byerly MS, Baronowsky EA, Chi MM, Powley TL (2002) Selective loss of vagal intramuscular mechanoreceptors in mice mutant for steel factor, the c-Kit receptor ligand. Anat Embryol 205:325\u2013342","journal-title":"Anat Embryol"},{"key":"957_CR13","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s00429-003-0371-0","volume":"208","author":"M Fu","year":"2004","unstructured":"Fu M, Tam PK, Sham MH, Lui VC (2004) Embryonic development of the ganglion plexuses and the concentric layer structure of human gut: a topographical study. Anat Embryol 208:33\u201341","journal-title":"Anat Embryol"},{"key":"957_CR14","first-page":"G1309","volume":"275","author":"R Hagger","year":"1998","unstructured":"Hagger R, Gharaie S, Finlayson C, Kumar D (1998) Regional and transmural density of interstitial cells of Cajal in human colon and rectum. Am J Physiol 275:G1309\u2013G1316","journal-title":"Am J Physiol"},{"key":"957_CR15","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0074-7696(04)42006-3","volume":"242","author":"M Hanani","year":"2005","unstructured":"Hanani M, Farrugia G, Komuro T (2005) Intercellular coupling of interstitial cells of Cajal in the digestive tract. Int Rev Cytol 242:249\u2013282","journal-title":"Int Rev Cytol"},{"key":"957_CR16","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1053\/j.gastro.2008.02.074","volume":"134","author":"JD Huizinga","year":"2008","unstructured":"Huizinga JD, White EJ (2008) Progenitor cells of interstitial cells of Cajal: on the road to tissue repair. Gastroenterology 134:1252\u20131254","journal-title":"Gastroenterology"},{"key":"957_CR17","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/373347a0","volume":"373","author":"JD Huizinga","year":"1995","unstructured":"Huizinga JD, Thuneberg L, Kluppel M, Malysz J, Mikkelsen HB, Bernstein A (1995) W\/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature 373:347\u2013349","journal-title":"Nature"},{"key":"957_CR18","doi-asserted-by":"crossref","first-page":"R302","DOI":"10.1152\/ajpregu.00398.2007","volume":"294","author":"JD Huizinga","year":"2008","unstructured":"Huizinga JD, Reed DE, Berezin I, Wang XY, Valdez DT, Liu LWC, Diamant N (2008) Survival dependency of intramuscular ICC on vagal afferent nerves in the cat esophagus. Am J Physiol Regul Integr Comp Physiol 294:R302\u2013R310","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"957_CR19","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1111\/j.1365-2982.2007.01075.x","volume":"20","author":"B Kallmunzer","year":"2008","unstructured":"Kallmunzer B, Sorensen B, Neuhuber WL, Worl J (2008) Enteric co-innervation of striated muscle fibers in human oesophagus. Neurogastroenterol Motil 20:597\u2013610","journal-title":"Neurogastroenterol Motil"},{"key":"957_CR20","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1016\/S0022-3468(99)90160-4","volume":"34","author":"SE Kenny","year":"1999","unstructured":"Kenny SE, Connell G, Woodward MN, Lloyd DA, Gosden CM, Edgar DH, Vaillant C (1999) Ontogeny of interstitial cells of Cajal in the human intestine. J Pediatr Surg 34:1241\u20131247","journal-title":"J Pediatr Surg"},{"key":"957_CR21","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1097\/00000478-200305000-00010","volume":"27","author":"K Khelif","year":"2003","unstructured":"Khelif K, De Laet MH, Chaouachi B, Segers V, Vanderwinden JM (2003) Achalasia of the cardia in Allgrove\u2019s (triple A) syndrome: histopathologic study of 10 cases. Am J Surg Pathol 27:667\u2013672","journal-title":"Am J Surg Pathol"},{"key":"957_CR22","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1113\/jphysiol.2006.116624","volume":"576","author":"T Komuro","year":"2006","unstructured":"Komuro T (2006) Structure and organization of interstitial cells of Cajal in the gastrointestinal tract. J Physiol (Lond) 576:653\u2013658","journal-title":"J Physiol (Lond)"},{"key":"957_CR23","author":"B Kuo","year":"2006","unstructured":"Kuo B, Urma D (2006) Esophagus\u2014anatomy and development. GI Motility online. doi: 10.1038\/gimo6","journal-title":"GI Motility online"},{"key":"957_CR24","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1242\/dev.122.3.725","volume":"122","author":"L Lecoin","year":"1996","unstructured":"Lecoin L, Gabella G, Le Douarin N (1996) Origin of the c-kit-positive interstitial cells in the avian bowel. Development 122:725\u2013733","journal-title":"Development"},{"key":"957_CR25","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1242\/dev.116.2.369","volume":"116","author":"H Maeda","year":"1992","unstructured":"Maeda H, Yamagata A, Nishikawa S, Yoshinaga K, Kobayashi S, Nishi K (1992) Requirement of c-kit for development of intestinal pacemaker system. Development 116:369\u2013375","journal-title":"Development"},{"key":"957_CR26","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1111\/j.1582-4934.2006.tb00541.x","volume":"10","author":"KW Min","year":"2006","unstructured":"Min KW, Leabu M (2006) Interstitial cells of Cajal (ICC) and gastrointestinal stromal tumor (GIST): facts, speculations, and myths. J Cell Mol Med 10:995\u20131013","journal-title":"J Cell Mol Med"},{"key":"957_CR27","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s00441-002-0592-1","volume":"309","author":"R Mitsui","year":"2002","unstructured":"Mitsui R, Komuro T (2002) Direct and indirect innervation of smooth muscle cells of rat stomach, with special reference to the interstitial cells of Cajal. Cell Tissue Res 309:219\u2013227","journal-title":"Cell Tissue Res"},{"key":"957_CR28","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1007\/s00383-003-1026-1","volume":"19","author":"CJ Newman","year":"2003","unstructured":"Newman CJ, Laurini RN, Lesbros Y, Reinberg O, Meyrat BJ (2003) Interstitial cells of Cajal are normally distributed in both ganglionated and aganglionic bowel in Hirschsprung\u2019s disease. Pediatr Surg Int 19:662\u2013668","journal-title":"Pediatr Surg Int"},{"key":"957_CR29","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.5858\/2003-127-1182-DOHOIN","volume":"127","author":"AP Piotrowska","year":"2003","unstructured":"Piotrowska AP, Solari V, Puri P (2003) Distribution of heme oxygenase-2 in nerves and interstitial cells of Cajal in the normal pylorus and in infantile hypertrophic pyloric stenosis. Arch Pathol Lab Med 127:1182\u20131186","journal-title":"Arch Pathol Lab Med"},{"key":"957_CR30","doi-asserted-by":"crossref","first-page":"G306","DOI":"10.1152\/ajpgi.1999.277.2.G306","volume":"277","author":"HG Preiksaitis","year":"1999","unstructured":"Preiksaitis HG, Diamant NE (1999) Myogenic mechanism for peristalsis in the cat esophagus. Am J Physiol Gastrointest Liver Physiol 277:G306\u2013G313","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"957_CR31","author":"G Radenkovic","year":"2009","unstructured":"Radenkovic G, Savic V, Mitic D, Grahovac S, Bjelakovic M, Krstic M (2009) Development of c-kit immunopositive interstitial cells of Cajal in the human stomach. J Cell Mol Med. doi: 10.1111\/j.1582-4934.2009.00725.x","journal-title":"J Cell Mol Med"},{"key":"957_CR32","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1136\/gut.2005.086074","volume":"55","author":"CGP Roberts","year":"2008","unstructured":"Roberts CGP, Hummers LK, Ravich WJ, Wigley FM, Hutchins GM (2008) A case\u2013control study of the pathology of oesophageal disease in systemic sclerosis (scleroderma). Gut 55:1697\u20131703","journal-title":"Gut"},{"key":"957_CR33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s004410100418","volume":"306","author":"JJ Rumessen","year":"2001","unstructured":"Rumessen JJ, Kerchove d\u2019Exaerde A de, Mignon S, Bernex F, Timmermans J-P, Schiffmann SN, Panthier JJ, Vanderwinden JM (2001) Interstitial cells of Cajal in the striated musculature of the mouse esophagus. Cell Tissue Res 306:1\u201314","journal-title":"Cell Tissue Res"},{"key":"957_CR34","first-page":"452","volume":"11","author":"A Shafik","year":"2005","unstructured":"Shafik A, Ahmed I, Sibai OE, Shafik AA (2005) Interstitial cells of Cajal in reflux esophagitis: role in the pathogenesis of the disease. Med Sci Monit 11:452\u2013456","journal-title":"Med Sci Monit"},{"key":"957_CR35","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1113\/jphysiol.2002.033365","volume":"546","author":"H Suzuki","year":"2003","unstructured":"Suzuki H, Ward SM, Bayguinov YR, Edwards FR, Hirst GDS (2003) Involvement of intramuscular interstitial cells in nitrergic inhibition in the mouse gastric antrum. J Physiol (Lond) 546:751\u2013763","journal-title":"J Physiol (Lond)"},{"key":"957_CR36","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/1097-0185(20010101)262:1<110::AID-AR1016>3.0.CO;2-0","volume":"262","author":"L Thuneberg","year":"2001","unstructured":"Thuneberg L, Peters S (2001) Toward a concept of stretch-coupling in smooth muscle. I. Anatomy of intestinal segmentation and sleeve contraction. Anat Rec 262:110\u2013124","journal-title":"Anat Rec"},{"key":"957_CR37","first-page":"97","volume":"280","author":"S Torihashi","year":"1995","unstructured":"Torihashi S, Ward SM, Nishikawa S-I, Nishi K, Kobayashi S, Sanders KM (1995) C-kit-dependent development of interstitial cells and electrical activity in the murine gastrointestinal tract. Cell Tissue Res 280:97\u2013111","journal-title":"Cell Tissue Res"},{"key":"957_CR38","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0006-8993(96)00935-3","volume":"738","author":"S Torihashi","year":"1996","unstructured":"Torihashi S, Yoshida H, Nishikawa S, Kunisada T, Sanders KM (1996) Enteric neurons express Steel factor-lacZ transgene in the murine gastrointestinal tract. Brain Res 738:323\u2013328","journal-title":"Brain Res"},{"key":"957_CR39","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/S0165-1838(98)00174-X","volume":"75","author":"S Torihashi","year":"1999","unstructured":"Torihashi S, Horisawa M, Watanabe Y (1999) c-Kit immunoreactive interstitial cells in the human gastrointestinal tract. J Auton Nerv Syst 75:38\u201350","journal-title":"J Auton Nerv Syst"},{"key":"957_CR40","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s00441-004-1023-2","volume":"319","author":"AS Wallace","year":"2005","unstructured":"Wallace AS, Burns AJ (2005) Development of the enteric nervous system, smooth muscle and interstitial cells of Cajal in the human gastrointestinal tract. Cell Tissue Res 319:367\u2013382","journal-title":"Cell Tissue Res"},{"key":"957_CR41","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1046\/j.1365-2982.2003.00429.x","volume":"15","author":"XY Wang","year":"2003","unstructured":"Wang XY, Paterson C, Huizinga JD (2003) Cholinergic and nitrergic innervation of ICC-DMP and ICC-IM in the human small intestine. Neurogastroenterol Motil 15:531\u2013543","journal-title":"Neurogastroenterol Motil"},{"key":"957_CR42","doi-asserted-by":"crossref","first-page":"G602","DOI":"10.1152\/ajpgi.2001.281.3.G602","volume":"281","author":"SM Ward","year":"2001","unstructured":"Ward SM, Sanders KM (2001) Physiology and pathophysiology of the interstitial cells of Cajal: from bench to bedside. Am J Physiol Gastrointest Liver Physiol 281:G602\u2013G611","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"957_CR43","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1113\/jphysiol.1994.sp020343","volume":"480","author":"SM Ward","year":"1994","unstructured":"Ward SM, Burns AJ, Torihashi T, Sanders KM (1994) Mutation of the proto-onkogene c-kit blocks development of interstitial cells and electrical rhythmicity in murine intestine. J Physiol (Lond) 480:91\u201397","journal-title":"J Physiol (Lond)"},{"key":"957_CR44","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/S0016-5085(98)70198-2","volume":"115","author":"SM Ward","year":"1998","unstructured":"Ward SM, Morris G, Reese L, Wang XY, Sanders KM (1998) Interstitial cells of Cajal mediate enteric inhibitory neurotransmission in the lower esophageal and pyloric sphincters. Gastroenterology 115:314\u2013329","journal-title":"Gastroenterology"},{"key":"957_CR45","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1136\/gut.44.1.65","volume":"44","author":"T Wester","year":"1999","unstructured":"Wester T, Eriksson L, Olsson Y, Olsen L (1999) Interstitial cells of Cajal in the human fetal small bowel as shown by c-kit immunohistochemistry. Gut 44:65\u201371","journal-title":"Gut"},{"key":"957_CR46","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0092-8674(90)90297-R","volume":"63","author":"DE Williams","year":"1990","unstructured":"Williams DE, Eisenmann J, Baird A (1990) Identification of a ligand for the c-kit proto-oncogene. Cell 63:167\u2013174","journal-title":"Cell"},{"key":"957_CR47","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1002\/(SICI)1097-4547(20000201)59:3<384::AID-JNR13>3.0.CO;2-4","volume":"59","author":"JJ Wu","year":"2000","unstructured":"Wu JJ, Rothman TP, Gershon MD (2000) Development of the interstitial cell of Cajal: origin, kit dependence and neuronal and nonneuronal sources of kit ligand. J Neurosci Res 59:384\u2013401","journal-title":"J Neurosci Res"},{"key":"957_CR48","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s00441-002-0696-7","volume":"311","author":"M Wu","year":"2003","unstructured":"Wu M, Majewski M, Wojtkiewicz J, Vanderwinden JM, Adriaensen D, Timmermans JP (2003) Anatomical and neurochemical features of the extrinsic and intrinsic innervation of the striated muscle in the porcine esophagus: evidence for regional and species differences. Cell Tissue Res 311:289\u2013297","journal-title":"Cell Tissue Res"},{"key":"957_CR49","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1016\/S0016-5085(98)70262-8","volume":"115","author":"HM Young","year":"1998","unstructured":"Young HM, Torihashi S, Ciampoli D, Sanders KM (1998) Identification of neurons that express stem cell factor in the mouse intestine. Gastroenterology 115:898\u2013908","journal-title":"Gastroenterology"}],"container-title":["Cell and Tissue Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00441-010-0957-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00441-010-0957-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00441-010-0957-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,26]],"date-time":"2021-10-26T21:15:11Z","timestamp":1635282911000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00441-010-0957-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4,30]]},"references-count":49,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["957"],"URL":"https:\/\/doi.org\/10.1007\/s00441-010-0957-9","relation":{},"ISSN":["0302-766X","1432-0878"],"issn-type":[{"value":"0302-766X","type":"print"},{"value":"1432-0878","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4,30]]}}}