{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T10:15:17Z","timestamp":1778840117534,"version":"3.51.4"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2013,4,16]],"date-time":"2013-04-16T00:00:00Z","timestamp":1366070400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Tissue Res"],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1007\/s00441-013-1614-x","type":"journal-article","created":{"date-parts":[[2013,4,14]],"date-time":"2013-04-14T21:46:54Z","timestamp":1365976014000},"page":"469-478","source":"Crossref","is-referenced-by-count":37,"title":["Expression of insulin signalling components in the sensory epithelium of the human saccule"],"prefix":"10.1007","volume":"352","author":[{"given":"Eva","family":"Degerman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uwe","family":"Rauch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sven","family":"Lindberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per","family":"Caye-Thomasen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Hultg\u00e5rdh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e5ns","family":"Magnusson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,4,16]]},"reference":[{"key":"1614_CR1","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1084\/jem.20051342","volume":"203","author":"S Agrawal","year":"2006","unstructured":"Agrawal S, Anderson P, Durbeej M, van Rooijen N, Ivars F, Opdenakker G, Sorokin LM (2006) Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis. J Exp Med 203:1007\u20131019","journal-title":"J Exp Med"},{"key":"1614_CR2","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1097\/MAO.0b013e3181de46ae","volume":"31","author":"Y Agrawal","year":"2010","unstructured":"Agrawal Y, Carey JP, Della Santina CC, Schubert MC, Minor LB (2010) Diabetes, vestibular dysfunction, and falls: analyses from the National Health and Nutrition Examination Survey. Otol Neurotol 31:1445\u20131450","journal-title":"Otol Neurotol"},{"key":"1614_CR3","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1097\/WNR.0b013e32834273e9","volume":"22","author":"N Angunsri","year":"2011","unstructured":"Angunsri N, Taura A, Nakagawa T, Hayashi Y, Kitajiri S, Omi E, Ishikawa K, Ito J (2011) Insulin-like growth factor 1 protects vestibular hair cells from aminoglycosides. Neuroreport 22:38\u201343","journal-title":"Neuroreport"},{"key":"1614_CR4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7326\/0003-4819-149-1-200807010-00231","volume":"149","author":"KE Bainbridge","year":"2008","unstructured":"Bainbridge KE, Hoffman HJ, Cowie CC (2008) Diabetes and hearing impairment in the United States: audiometric evidence from the National Health and Nutrition Examination Survey, 1999 to 2004. Ann Intern Med 149:1\u201310","journal-title":"Ann Intern Med"},{"key":"1614_CR5","doi-asserted-by":"crossref","first-page":"16541","DOI":"10.1523\/JNEUROSCI.2430-11.2011","volume":"31","author":"S Bartolami","year":"2011","unstructured":"Bartolami S, Gaboyard S, Quentin J, Travo C, Cavalier M, Barhanin J, Chabbert C (2011) Critical roles of transitional cells and Na\/K-ATPase in the formation of vestibular endolymph. J Neurosci 31:16541\u201316549","journal-title":"J Neurosci"},{"key":"1614_CR6","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1186\/1471-2202-12-114","volume":"12","author":"Y Brand","year":"2011","unstructured":"Brand Y, Setz C, Levano S, Listyo A, Chavez E, Pak K, Sung M, Radojevic V, Ryan AF, Bodmer D (2011) Simvastatin protects auditory hair cells from gentamicin-induced toxicity and activates Akt signaling in vitro. BMC Neurosci 12:114","journal-title":"BMC Neurosci"},{"key":"1614_CR7","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/j.1460-9568.2005.04584.x","volume":"23","author":"R Cediel","year":"2006","unstructured":"Cediel R, Riquelme R, Contreras J, D\u00edaz A, Varela-Nieto I (2006) Sensorineural hearing loss in insulin-like growth factor I-null mice: a new model of human deafness. Eur J Neurosci 23:587\u2013590","journal-title":"Eur J Neurosci"},{"key":"1614_CR8","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1146\/annurev.biochem.76.060305.150444","volume":"76","author":"M Conti","year":"2007","unstructured":"Conti M, Beavo J (2007) Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling. Annu Rev Biochem 76:481\u2013511","journal-title":"Annu Rev Biochem"},{"key":"1614_CR9","doi-asserted-by":"crossref","first-page":"48","DOI":"10.3389\/fneur.2011.00048","volume":"2","author":"E Degerman","year":"2011","unstructured":"Degerman E, Rauch U, G\u00f6ransson O, Lindberg S, Hultg\u00e5rdh A, Magnusson M (2011a) Identification of new signaling components in the sensory epithelium of human saccule. Front Neurol 2:48","journal-title":"Front Neurol"},{"key":"1614_CR10","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.coph.2011.09.015","volume":"11","author":"E Degerman","year":"2011","unstructured":"Degerman E, Ahmad F, Chung YW, Guirguis E, Omar B, Stenson L, Manganiello V (2011b) From PDE3B to the regulation of energy homeostasis. Curr Opin Pharmacol 11:676\u2013682","journal-title":"Curr Opin Pharmacol"},{"key":"1614_CR11","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.neulet.2010.12.029","volume":"490","author":"M Edamatsu","year":"2011","unstructured":"Edamatsu M, Kondo Y, Ando M (2011) Multiple expression of glucose transporters in the lateral wall of the cochlear duct studied by quantitative real-time PCR assay. Neurosci Lett 490:72\u201377","journal-title":"Neurosci Lett"},{"key":"1614_CR12","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s00232-004-0703-x","volume":"201","author":"C Fauser","year":"2004","unstructured":"Fauser C, Schimanski S, Wangemann P (2004) Localization of beta1-adrenergic receptors in the cochlea and the vestibular labyrinth. J Membr Biol 201:25\u201332","journal-title":"J Membr Biol"},{"key":"1614_CR13","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1113\/jphysiol.1995.sp020955","volume":"488","author":"E F\u00e9raille","year":"1995","unstructured":"F\u00e9raille E, Rousselot M, Rajerison R, Favre H (1995) Effect of insulin on Na+,K+-ATPase in rat collecting duct. J Physiol (Lond) 488:171\u2013180","journal-title":"J Physiol (Lond)"},{"key":"1614_CR14","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1152\/jn.1976.39.5.970","volume":"39","author":"C Fern\u00e1ndez","year":"1976","unstructured":"Fern\u00e1ndez C, Goldberg JM (1976) Physiology of peripheral neurons innervating otolith organs of the squirrel monkey. I. Response to static tilts and to long-duration centrifugal force. J Neurophysiol 39:970\u2013984","journal-title":"J Neurophysiol"},{"key":"1614_CR15","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1152\/jn.1976.39.5.985","volume":"39","author":"C Fern\u00e1ndez","year":"1976","unstructured":"Fern\u00e1ndez C, Goldberg JM (1976) Physiology of peripheral neurons innervating otolith organs of the squirrel monkey. II. Directional selectivity and force-response relations.J Neurophysiol 39:985\u2013995","journal-title":"J Neurophysiol"},{"key":"1614_CR16","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1152\/jn.1976.39.5.996","volume":"39","author":"C Fern\u00e1ndez","year":"1976","unstructured":"Fern\u00e1ndez C, Goldberg JM (1976) Physiology of peripheral neurons innervating otolith organs of the squirrel monkey. III. Response dynamics.J Neurophysiol 39:996\u20131008","journal-title":"J Neurophysiol"},{"key":"1614_CR17","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.heares.2005.09.002","volume":"211","author":"ST Frisina","year":"2006","unstructured":"Frisina ST, Mapes F, Kim S, Frisina DR, Frisina RD (2006) Characterization of hearing loss in aged type II diabetics. Hear Res 211:103\u2013113","journal-title":"Hear Res"},{"key":"1614_CR18","doi-asserted-by":"crossref","first-page":"2980","DOI":"10.2337\/db11-1845","volume":"61","author":"T Fujita","year":"2012","unstructured":"Fujita T, Yamashita D, Katsunuma S, Hasegawa S, Tanimoto H, Nibu KI (2012) Increased inner ear susceptibility to noise injury in mice with streptozotocin-induced diabetes. Diabetes 61:2980\u20132986","journal-title":"Diabetes"},{"key":"1614_CR19","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.otohns.2005.02.004","volume":"133","author":"H Fukushima","year":"2005","unstructured":"Fukushima H, Cureoglu S, Schachern PA, Kusunoki T, Oktay MF, Fukushima N, Paparella MM, Harada T (2005) Cochlear changes in patients with type 1 diabetes mellitus. Otolaryngol Head Neck Surg 133:100\u2013106","journal-title":"Otolaryngol Head Neck Surg"},{"key":"1614_CR20","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1001\/archotol.132.9.934","volume":"132","author":"H Fukushima","year":"2006","unstructured":"Fukushima H, Cureoglu S, Schachern PA, Paparella MM, Harada T, Oktay MF (2006) Effects of type 2 diabetes mellitus on cochlear structure in humans. Arch Otolaryngol Head Neck Surg 132:934\u2013938","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"1614_CR21","doi-asserted-by":"crossref","first-page":"6111","DOI":"10.3748\/wjg.v16.i48.6111","volume":"16","author":"JW Han","year":"2010","unstructured":"Han JW, Zhan XR, Li XY, Xia B, Wang YY, Zhang J, Li BX (2010) Impaired PI3K\/Akt signal pathway and hepatocellular injury in high-fat fed rats. World J Gastroenterol 16:6111\u20136118","journal-title":"World J Gastroenterol"},{"key":"1614_CR22","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1038\/nm.2084","volume":"16","author":"AM Houghton","year":"2010","unstructured":"Houghton AM, Rzymkiewicz DM, Ji H, Gregory AD, Egea EE, Metz HE, Stolz DB, Land SR, Marconcini LA, Kliment CR, Jenkins KM, Beaulieu KA, Mouded M, Frank SJ, Wong KK, Shapiro SD (2010) Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth. Nat Med 16:219\u2013212","journal-title":"Nat Med"},{"key":"1614_CR23","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1007\/BF00401834","volume":"38","author":"T Ishikawa","year":"1995","unstructured":"Ishikawa T, Naito Y, Taniguchi K (1995) Hearing impairment in WBN\/Kob rats with spontaneous diabetes mellitus. Diabetologia 38:649\u2013655","journal-title":"Diabetologia"},{"key":"1614_CR24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.heares.2009.03.014","volume":"254","author":"A Ishiyama","year":"2009","unstructured":"Ishiyama A, Mowry SE, Lopez IA, Ishiyama G (2009) Immunohistochemical distribution of basement membrane proteins in the human inner ear from older subjects. Hear Res 254:1\u201314","journal-title":"Hear Res"},{"key":"1614_CR25","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s00441-010-0975-7","volume":"340","author":"G Ishiyama","year":"2010","unstructured":"Ishiyama G, Lopez IA, Beltran-Parrazal L, Ishiyama A (2010) Immunohistochemical localization and mRNA expression of aquaporins in the macula utriculi of patients with Meniere\u2019s disease and acoustic neuroma. Cell Tissue Res 340:407\u2013419","journal-title":"Cell Tissue Res"},{"key":"1614_CR26","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1097\/00129492-200305000-00006","volume":"24","author":"V Kakarlapudi","year":"2003","unstructured":"Kakarlapudi V, Sawyer R, Staecker H (2003) The effect of diabetes on sensorineural hearing loss. Otol Neurotol 24:382\u2013386","journal-title":"Otol Neurotol"},{"key":"1614_CR27","doi-asserted-by":"crossref","first-page":"3000","DOI":"10.1002\/jnr.21404","volume":"85","author":"KM Khan","year":"2007","unstructured":"Khan KM, Drescher MJ, Hatfield JS, Ramakrishnan NA, Drescher DG (2007) Immunohistochemical localization of adrenergic receptors in the rat organ of Corti and spiral ganglion. J Neurosci Res 85:3000\u20133012","journal-title":"J Neurosci Res"},{"key":"1614_CR28","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S1808-8694(15)30079-3","volume":"73","author":"KF Klagenberg","year":"2007","unstructured":"Klagenberg KF, Zeigelboim BS, Jurkiewicz AL, Martins-Bassetto J (2007) Vestibulocochlear manifestations in patients with type I diabetes mellitus. Braz J Otorhinolaryngol 73:353\u2013358","journal-title":"Braz J Otorhinolaryngol"},{"key":"1614_CR29","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1288\/00005537-199506000-00014","volume":"105","author":"LC Knight","year":"1995","unstructured":"Knight LC, Saeed SR, Hradek GT, Schindler RA (1995) Insulin receptors on the endolymphatic sac: an autoradiographic study. Laryngoscope 105:635\u2013638","journal-title":"Laryngoscope"},{"key":"1614_CR30","doi-asserted-by":"crossref","first-page":"211","DOI":"10.3342\/ceo.2008.1.4.211","volume":"1","author":"HS Lee","year":"2008","unstructured":"Lee HS, Kim KR, Chung WH, Cho YS, Hong SH (2008) Early sensorineural hearing loss in ob\/ob mouse, an animal model of type 2 diabetes. Clin Exp Otorhinolaryngol 1:211\u2013216","journal-title":"Clin Exp Otorhinolaryngol"},{"key":"1614_CR31","doi-asserted-by":"crossref","first-page":"549","DOI":"10.4158\/EP11389.OR","volume":"18","author":"I Lerman-Garber","year":"2012","unstructured":"Lerman-Garber I, Cuevas-Ramos D, Vald\u00e9s S, Enr\u00edquez L, Lobato M, Osornio M, Escobedo AR, Pascual-Ramos V, Mehta R, Ram\u00edrez-Anguiano J, G\u00f3mez-P\u00e9rez FJ (2012) Sensorineural hearing loss\u2014a common finding in early-onset type 2 diabetes mellitus. Endocr Pract 18:549\u2013557","journal-title":"Endocr Pract"},{"key":"1614_CR32","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/nrm3351","volume":"13","author":"D Leto","year":"2012","unstructured":"Leto D, Saltiel AR (2012) Regulation of glucose transport by insulin: traffic control of GLUT4. Nat Rev Mol Cell Biol 13:383\u2013396","journal-title":"Nat Rev Mol Cell Biol"},{"key":"1614_CR33","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1097\/00129492-200105000-00008","volume":"22","author":"G Lisowska","year":"2001","unstructured":"Lisowska G, Namys\u0142owski G, Morawski K, Strojek K (2001) Early identification of hearing impairment in patients with type 1 diabetes mellitus. Otol Neurotol 22:316\u2013320","journal-title":"Otol Neurotol"},{"key":"1614_CR34","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s00441-007-0380-z","volume":"328","author":"IA Lopez","year":"2007","unstructured":"Lopez IA, Ishiyama G, Lee M, Baloh RW, Ishiyama A (2007) Immunohistochemical localization of aquaporins in the human inner ear. Cell Tissue Res 328:453\u2013460","journal-title":"Cell Tissue Res"},{"key":"1614_CR35","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1111\/j.1365-2826.2010.02060.x","volume":"22","author":"C Maekawa","year":"2010","unstructured":"Maekawa C, Kitahara T, Kizawa K, Okazaki S, Kamakura T, Horii A, Imai T, Doi K, Inohara H, Kiyama H (2010) Expression and translocation of aquaporin-2 in the endolymphatic sac in patients with Meniere\u2019s disease. J Neuroendocrinol 22:1157\u20131164","journal-title":"J Neuroendocrinol"},{"key":"1614_CR36","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3389\/fnmol.2011.00011","volume":"4","author":"S Murillo-Cuesta","year":"2011","unstructured":"Murillo-Cuesta S, Rodr\u00edguez-de la Rosa L, Cediel R, Lassaletta L, Varela-Nieto I (2011) The role of insulin-like growth factor-I in the physiopathology of hearing. Front Mol Neurosci 4:11","journal-title":"Front Mol Neurosci"},{"key":"1614_CR37","doi-asserted-by":"crossref","first-page":"260","DOI":"10.2119\/molmed.2011.00328","volume":"18","author":"S Murillo-Cuesta","year":"2012","unstructured":"Murillo-Cuesta S, Camarero G, Gonz\u00e1lez-Rodr\u00edguez A, De La Rosa LR, Burks DJ, Avenda\u00f1o C, Valverde AM, Varela-Nieto I (2012) Insulin receptor substrate 2 (IRS2)-deficient mice show sensorineural hearing loss that is delayed by concomitant protein tyrosine phosphatase 1B (PTP1B) loss of function. Mol Med 18:260\u2013269","journal-title":"Mol Med"},{"key":"1614_CR38","doi-asserted-by":"crossref","first-page":"e13351","DOI":"10.1371\/journal.pone.0013351","volume":"5","author":"M Nakou","year":"2010","unstructured":"Nakou M, Bertsias G, Stagakis I, Centola M, Tassiulas I, Hatziapostolou M, Kritikos I, Goulielmos G, Boumpas DT, Iliopoulos D (2010) Gene network analysis of bone marrow mononuclear cells reveals activation of multiple kinase pathways in human systemic lupus erythematosus. PLoS One 5:e13351","journal-title":"PLoS One"},{"issue":"5","key":"1614_CR39","doi-asserted-by":"crossref","first-page":"3371","DOI":"10.1074\/jbc.M006739200","volume":"276","author":"S Palacios","year":"2001","unstructured":"Palacios S, Lalioti V, Martinez-Arca S, Chattopadhyay S, Sandoval IV (2001) Recycling of the insulin-sensitive glucose transporter GLUT4. Access of surface internalized GLUT4 molecules to the perinuclear storage compartment is mediated by the Phe5-Gln6-Gln7-Ile8 motif. J Biol Chem 276(5):3371\u20133383","journal-title":"J Biol Chem"},{"key":"1614_CR40","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1097\/00005537-200101000-00019","volume":"111","author":"R Perez","year":"2001","unstructured":"Perez R, Ziv E, Freeman S, Sichel JY, Sohmer H (2001) Vestibular end-organ impairment in an animal model of type 2 diabetes mellitus. Laryngoscope 111:110\u2013113","journal-title":"Laryngoscope"},{"key":"1614_CR41","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1083\/jcb.111.4.1685","volume":"111","author":"JR Sanes","year":"1990","unstructured":"Sanes JR, Engvall E, Butkowski R, Hunter DD (1990) Molecular heterogeneity of basal laminae: isoforms of laminin and collagen IV at the neuromuscular junction and elsewhere. J Cell Biol 111:1685\u20131699","journal-title":"J Cell Biol"},{"key":"1614_CR42","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.heares.2009.09.002","volume":"264","author":"SH Sha","year":"2010","unstructured":"Sha SH, Chen FQ, Schacht J (2010) PTEN attenuates PIP3\/Akt signaling in the cochlea of the aging CBA\/J mouse. Hear Res 264:86\u201392","journal-title":"Hear Res"},{"key":"1614_CR43","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1097\/mlg.0b013e318031c802","volume":"117","author":"D Taguchi","year":"2007","unstructured":"Taguchi D, Takeda T, Kakigi A, Takumida M, Nishioka R, Kitano H (2007) Expressions of aquaporin-2, vasopressin type 2 receptor, transient receptor potential channel vanilloid (TRPV)1, and TRPV4 in the human endolymphatic sac. Laryngoscope 117:695\u2013698","journal-title":"Laryngoscope"},{"issue":"Suppl 1","key":"1614_CR44","first-page":"1","volume":"71","author":"T Takeda","year":"2010","unstructured":"Takeda T, Takeda S, Kakigi A, Okada T, Nishioka R, Taguchi D, Nishimura M, Nakatani H (2010) Hormonal aspects of M\u00e9ni\u00e8re\u2019s disease on the basis of clinical and experimental studies. ORL J Otorhinolaryngol Relat Spec 71 (Suppl 1):1\u20139","journal-title":"ORL J Otorhinolaryngol Relat Spec"},{"key":"1614_CR45","doi-asserted-by":"crossref","first-page":"142","DOI":"10.3109\/00016489.2010.524939","volume":"131","author":"M Takumida","year":"2011","unstructured":"Takumida M, Anniko M (2011) Localization of prostanoid receptors in the mouse inner ear. Acta Otolaryngol 131:142\u2013148","journal-title":"Acta Otolaryngol"},{"key":"1614_CR46","first-page":"807","volume":"132","author":"M Takumida","year":"2012","unstructured":"Takumida M, Kakigi A, Egami N, Nishioka R, Anniko M (2012) Localization of aquaporins 1, 2, and 3 and vasopressin type 2 receptor in the mouse inner ear. Acta Otolaryngol 132:807\u2013813","journal-title":"Acta Otolaryngol"},{"key":"1614_CR47","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/nrm1837","volume":"7","author":"CM Taniguchi","year":"2006","unstructured":"Taniguchi CM, Emanuelli B, Kahn CR (2006) Critical nodes in signalling pathways: insights into insulin action. Nat Rev Mol Cell Biol 7:85\u201396","journal-title":"Nat Rev Mol Cell Biol"},{"key":"1614_CR48","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.heares.2009.01.007","volume":"249","author":"ON Vasilyeva","year":"2009","unstructured":"Vasilyeva ON, Frisina ST, Zhu X, Walton JP, Frisina RD (2009) Interactions of hearing loss and diabetes mellitus in the middle age CBA\/CaJ mouse model of presbycusis. Hear Res 249:44\u201353","journal-title":"Hear Res"},{"key":"1614_CR49","first-page":"42","volume":"59","author":"P Wangemann","year":"2002","unstructured":"Wangemann P (2002) Adrenergic and muscarinic control of cochlear endolymph production. Adv Otorhinolaryngol 59:42\u201350","journal-title":"Adv Otorhinolaryngol"}],"container-title":["Cell and Tissue Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00441-013-1614-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00441-013-1614-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00441-013-1614-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,12]],"date-time":"2019-07-12T10:31:21Z","timestamp":1562927481000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00441-013-1614-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,16]]},"references-count":49,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["1614"],"URL":"https:\/\/doi.org\/10.1007\/s00441-013-1614-x","relation":{},"ISSN":["0302-766X","1432-0878"],"issn-type":[{"value":"0302-766X","type":"print"},{"value":"1432-0878","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,16]]}}}