{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T05:48:59Z","timestamp":1790401739505,"version":"4.1.0"},"reference-count":73,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2015,9,4]],"date-time":"2015-09-04T00:00:00Z","timestamp":1441324800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell Tissue Res"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1007\/s00441-015-2270-0","type":"journal-article","created":{"date-parts":[[2015,9,4]],"date-time":"2015-09-04T01:05:24Z","timestamp":1441328724000},"page":"97-104","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Macrophages and dendritic cells in the post-testicular environment"],"prefix":"10.1007","volume":"363","author":[{"given":"Nicolas","family":"Da Silva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire R.","family":"Barton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,9,4]]},"reference":[{"key":"2270_CR1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/ar.1092090208","volume":"209","author":"K Abe","year":"1984","unstructured":"Abe K, Takano H, Ito T (1984) Microvasculature of the mouse epididymis, with special reference to fenestrated capillaries localized in the initial segment. Anat Rec 209:209\u2013218","journal-title":"Anat Rec"},{"key":"2270_CR2","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1071\/RD13301","volume":"26","author":"S Arrighi","year":"2014","unstructured":"Arrighi S (2014) Are the basal cells of the mammalian epididymis still an enigma? Reprod Fertil Dev 26:1061\u20131071","journal-title":"Reprod Fertil Dev"},{"key":"2270_CR3","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1159\/000147574","volume":"149","author":"S Arrighi","year":"1994","unstructured":"Arrighi S, Romanello MG, Domeneghini C (1994) Ultrastructure of the epithelium that lines the ductuli efferentes in domestic equidae, with particular reference to spermatophagy. Acta Anat 149:174\u2013184","journal-title":"Acta Anat"},{"key":"2270_CR4","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1038\/ni.2967","volume":"15","author":"CC Bain","year":"2014","unstructured":"Bain CC, Bravo-Blas A, Scott CL, Gomez Perdiguero E, Geissmann F, Henri S, Malissen B, Osborne LC, Artis D, Mowat AM (2014) Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice. Nat Immunol 15:929\u2013937","journal-title":"Nat Immunol"},{"key":"2270_CR5","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1007\/s00441-012-1381-0","volume":"349","author":"C Belleannee","year":"2012","unstructured":"Belleannee C, Thimon V, Sullivan R (2012) Region-specific gene expression in the epididymis. Cell Tissue Res 349:717\u2013731","journal-title":"Cell Tissue Res"},{"key":"2270_CR6","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.coi.2013.07.004","volume":"25","author":"ZB Bjornson","year":"2013","unstructured":"Bjornson ZB, Nolan GP, Fantl WJ (2013) Single-cell mass cytometry for analysis of immune system functional states. Curr Opin Immunol 25:484\u2013494","journal-title":"Curr Opin Immunol"},{"key":"2270_CR7","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.immuni.2012.09.018","volume":"38","author":"SY Chang","year":"2013","unstructured":"Chang SY, Song JH, Guleng B, Cotoner CA, Arihiro S, Zhao Y, Chiang HS, O'Keeffe M, Liao G, Karp CL, Kweon MN, Sharpe AH, Bhan A, Terhorst C, Reinecker HC (2013) Circulatory antigen processing by mucosal dendritic cells controls CD8(+) T cell activation. Immunity 38:153\u2013165","journal-title":"Immunity"},{"key":"2270_CR8","doi-asserted-by":"crossref","unstructured":"Cooper TG (2015) Epididymal research: more warp than weft? Asian J Androl (in press)","DOI":"10.4103\/1008-682X.146102"},{"key":"2270_CR9","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1242\/jcs.115.1.5","volume":"115","author":"TG Cooper","year":"2002","unstructured":"Cooper TG, Yeung CH, Jones R, Orgebin-Crist MC, Robaire B (2002) Rebuttal of a role for the epididymis in sperm quality control by phagocytosis of defective sperm. J Cell Sci 115:5\u20137","journal-title":"J Cell Sci"},{"key":"2270_CR10","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1093\/humupd\/dmn055","volume":"15","author":"GA Cornwall","year":"2009","unstructured":"Cornwall GA (2009) New insights into epididymal biology and function. Hum Reprod Update 15:213\u2013227","journal-title":"Hum Reprod Update"},{"key":"2270_CR11","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1530\/REP-10-0493","volume":"141","author":"N Silva Da","year":"2011","unstructured":"Da Silva N, Cortez-Retamozo V, Reinecker HC, Wildgruber M, Hill E, Brown D, Swirski FK, Pittet MJ, Breton S (2011) A dense network of dendritic cells populates the murine epididymis. Reproduction 141:653\u2013663","journal-title":"Reproduction"},{"key":"2270_CR12","doi-asserted-by":"crossref","first-page":"R27","DOI":"10.1530\/REP-13-0420","volume":"147","author":"JL Dacheux","year":"2014","unstructured":"Dacheux JL, Dacheux F (2014) New insights into epididymal function in relation to sperm maturation. Reproduction 147:R27\u2013R42","journal-title":"Reproduction"},{"key":"2270_CR13","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1038\/ni.2705","volume":"14","author":"LC Davies","year":"2013","unstructured":"Davies LC, Jenkins SJ, Allen JE, Taylor PR (2013) Tissue-resident macrophages. Nat Immunol 14:986\u2013995","journal-title":"Nat Immunol"},{"key":"2270_CR14","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1093\/molehr\/gau050","volume":"20","author":"JR Dorin","year":"2014","unstructured":"Dorin JR, Barratt CL (2014) Importance of beta-defensins in sperm function. Mol Hum Reprod 20:821\u2013826","journal-title":"Mol Hum Reprod"},{"key":"2270_CR15","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1007\/978-1-4614-4711-5_11","volume":"763","author":"E Dube","year":"2012","unstructured":"Dube E, Cyr DG (2012) The blood-epididymis barrier and human male fertility. Adv Exp Med Biol 763:218\u2013236","journal-title":"Adv Exp Med Biol"},{"key":"2270_CR16","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1038\/mi.2008.27","volume":"1","author":"JV Forrester","year":"2008","unstructured":"Forrester JV, Xu H, Lambe T, Cornall R (2008) Immune privilege or privileged immunity? Mucosal Immunol 1:372\u2013381","journal-title":"Mucosal Immunol"},{"key":"2270_CR17","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.immuni.2012.07.011","volume":"37","author":"MY Gerner","year":"2012","unstructured":"Gerner MY, Kastenmuller W, Ifrim I, Kabat J, Germain RN (2012) Histo-cytometry: a method for highly multiplex quantitative tissue imaging analysis applied to dendritic cell subset microanatomy in lymph nodes. Immunity 37:364\u2013376","journal-title":"Immunity"},{"key":"2270_CR18","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1038\/nri3671","volume":"14","author":"F Ginhoux","year":"2014","unstructured":"Ginhoux F, Jung S (2014) Monocytes and macrophages: developmental pathways and tissue homeostasis. Nat Rev Immunol 14:392\u2013404","journal-title":"Nat Rev Immunol"},{"key":"2270_CR19","doi-asserted-by":"crossref","unstructured":"Gomez Perdiguero E, Klapproth K, Schulz C, Busch K, Azzoni E, Crozet L, Garner H, Trouillet C, Bruijn MF de, Geissmann F, Rodewald HR (2015) Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors. Nature 518:547\u2013551","DOI":"10.1038\/nature13989"},{"key":"2270_CR20","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1016\/j.cell.2014.11.023","volume":"159","author":"D Gosselin","year":"2014","unstructured":"Gosselin D, Link VM, Romanoski CE, Fonseca GJ, Eichenfield DZ, Spann NJ, Stender JD, Chun HB, Garner H, Geissmann F, Glass CK (2014) Environment drives selection and function of enhancers controlling tissue-specific macrophage identities. Cell 159:1327\u20131340","journal-title":"Cell"},{"key":"2270_CR21","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1038\/nri3712","volume":"14","author":"M Guilliams","year":"2014","unstructured":"Guilliams M, Ginhoux F, Jakubzick C, Naik SH, Onai N, Schraml BU, Segura E, Tussiwand R, Yona S (2014) Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny. Nat Rev Immunol 14:571\u2013578","journal-title":"Nat Rev Immunol"},{"key":"2270_CR22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2051-4190-23-8","volume":"23","author":"R Guiton","year":"2013","unstructured":"Guiton R, Henry-Berger J, Drevet JR (2013) The immunobiology of the mammalian epididymis: the black box is now open! Basic Clin Androl 23:1\u201310","journal-title":"Basic Clin Androl"},{"key":"2270_CR23","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1745-7262.2007.00298.x","volume":"9","author":"SH Hall","year":"2007","unstructured":"Hall SH, Yenugu S, Radhakrishnan Y, Avellar MC, Petrusz P, French FS (2007) Characterization and functions of beta defensins in the epididymis. Asian J Androl 9:453\u2013462","journal-title":"Asian J Androl"},{"key":"2270_CR24","doi-asserted-by":"crossref","first-page":"e23140","DOI":"10.4161\/onci.23140","volume":"2","author":"M Haniffa","year":"2013","unstructured":"Haniffa M, Collin M, Ginhoux F (2013) Identification of human tissue cross-presenting dendritic cells: a new target for cancer vaccines. Oncoimmunology 2:e23140","journal-title":"Oncoimmunology"},{"key":"2270_CR25","doi-asserted-by":"crossref","first-page":"625","DOI":"10.2164\/jandrol.111.012989","volume":"32","author":"MP Hedger","year":"2011","unstructured":"Hedger MP (2011) Immunophysiology and pathology of inflammation in the testis and epididymis. J Androl 32:625\u2013640","journal-title":"J Androl"},{"key":"2270_CR26","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/B978-012515400-0\/50030-0","volume-title":"Knobil and Neill's physiology of reproduction","author":"MP Hedger","year":"2006","unstructured":"Hedger MP, Hales DB (2006) Immunophysiology of the male reproductive tract. In: Neill JD (ed) Knobil and Neill's physiology of reproduction, vol 1. Elsevier Academic, Amsterdam, pp 1195\u20131286"},{"key":"2270_CR27","unstructured":"Hermo L, Robaire B (2002) Epididymal cell types and thier functions. In: Robaire B, Hinton BT (eds) The epididymis: from molecular to clinical practice. A comprehensive survey of the efferent ducts, the epididymis and the vas deferens. Kluwer Academic\/Plenum, New York, pp 81\u2013102"},{"key":"2270_CR28","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s00795-009-0473-8","volume":"43","author":"S Hirai","year":"2010","unstructured":"Hirai S, Naito M, Terayama H, Ning Q, Miura M, Shirakami G, Itoh M (2010) Difference in abundance of blood and lymphatic capillaries in the murine epididymis. Med Mol Morphol 43:37\u201342","journal-title":"Med Mol Morphol"},{"key":"2270_CR29","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.immuni.2015.03.011","volume":"42","author":"G Hoeffel","year":"2015","unstructured":"Hoeffel G, Chen J, Lavin Y, Low D, Almeida FF, See P, Beaudin AE, Lum J, Low I, Forsberg EC, Poidinger M, Zolezzi F, Larbi A, Ng LG, Chan JK, Greter M, Becher B, Samokhvalov IM, Merad M, Ginhoux F (2015) C-myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages. Immunity 42:665\u2013678","journal-title":"Immunity"},{"key":"2270_CR30","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1111\/j.1439-0272.1978.tb03044.x","volume":"10","author":"AF Holstein","year":"1978","unstructured":"Holstein AF (1978) Spermatophagy in the seminiferous tubules and excurrent ducts of the testis in Rhesus monkey and in man. Andrologia 10:331\u2013352","journal-title":"Andrologia"},{"key":"2270_CR31","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/nri3254","volume":"12","author":"OP Joffre","year":"2012","unstructured":"Joffre OP, Segura E, Savina A, Amigorena S (2012) Cross-presentation by dendritic cells. Nat Rev Immunol 12:557\u2013569","journal-title":"Nat Rev Immunol"},{"key":"2270_CR32","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1095\/biolreprod.104.031252","volume":"71","author":"R Jones","year":"2004","unstructured":"Jones R (2004) Sperm survival versus degradation in the mammalian epididymis: a hypothesis. Biol Reprod 71:1405\u20131411","journal-title":"Biol Reprod"},{"key":"2270_CR33","doi-asserted-by":"crossref","first-page":"e66494","DOI":"10.1371\/journal.pone.0066494","volume":"8","author":"A Jrad-Lamine","year":"2013","unstructured":"Jrad-Lamine A, Henry-Berger J, Damon-Soubeyrand C, Saez F, Kocer A, Janny L, Pons-Rejraji H, Munn DH, Mellor AL, Gharbi N, Cadet R, Guiton R, Aitken RJ, Drevet JR (2013) Indoleamine 2,3-dioxygenase 1 (ido1) is involved in the control of mouse caput epididymis immune environment. PLoS One 8:e66494","journal-title":"PLoS One"},{"key":"2270_CR34","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1095\/biolreprod.114.123943","volume":"92","author":"B Kim","year":"2015","unstructured":"Kim B, Roy J, Shum WW, Da Silva N, Breton S (2015) Role of testicular luminal factors on basal cell elongation and proliferation in the mouse epididymis. Biol Reprod 92:9","journal-title":"Biol Reprod"},{"key":"2270_CR35","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1016\/j.cell.2014.11.018","volume":"159","author":"Y Lavin","year":"2014","unstructured":"Lavin Y, Winter D, Blecher-Gonen R, David E, Keren-Shaul H, Merad M, Jung S, Amit I (2014) Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment. Cell 159:1312\u20131326","journal-title":"Cell"},{"key":"2270_CR36","doi-asserted-by":"crossref","first-page":"13","DOI":"10.12703\/P6-13","volume":"6","author":"FO Martinez","year":"2014","unstructured":"Martinez FO, Gordon S (2014) The M1 and M2 paradigm of macrophage activation: time for reassessment. F1000prime Rep 6:13","journal-title":"F1000prime Rep"},{"key":"2270_CR37","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.immuni.2013.12.012","volume":"40","author":"E Mazzini","year":"2014","unstructured":"Mazzini E, Massimiliano L, Penna G, Rescigno M (2014) Oral tolerance can be established via gap junction transfer of fed antigens from CX3CR1(+) macrophages to CD103(+) dendritic cells. Immunity 40:248\u2013261","journal-title":"Immunity"},{"key":"2270_CR38","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1038\/nature10863","volume":"483","author":"JR McDole","year":"2012","unstructured":"McDole JR, Wheeler LW, McDonald KG, Wang B, Konjufca V, Knoop KA, Newberry RD, Miller MJ (2012) Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine. Nature 483:345\u2013349","journal-title":"Nature"},{"key":"2270_CR39","doi-asserted-by":"crossref","first-page":"e92603","DOI":"10.1371\/journal.pone.0092603","volume":"9","author":"A Mietens","year":"2014","unstructured":"Mietens A, Tasch S, Stammler A, Konrad L, Feuerstacke C, Middendorff R (2014) Time-lapse imaging as a tool to investigate contractility of the epididymal duct\u2014effects of cGMP signaling. PLoS One 9:e92603","journal-title":"PLoS One"},{"key":"2270_CR40","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.immuni.2014.04.016","volume":"40","author":"A Mildner","year":"2014","unstructured":"Mildner A, Jung S (2014) Development and function of dendritic cell subsets. Immunity 40:642\u2013656","journal-title":"Immunity"},{"key":"2270_CR41","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1095\/biolreprod.110.087452","volume":"84","author":"P Mital","year":"2011","unstructured":"Mital P, Hinton BT, Dufour JM (2011) The blood-testis and blood-epididymis barriers are more than just their tight junctions. Biol Reprod 84:851\u2013858","journal-title":"Biol Reprod"},{"key":"2270_CR42","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1089\/088922203763315740","volume":"19","author":"TE Mullen Jr","year":"2003","unstructured":"Mullen TE Jr, Kiessling RL, Kiessling AA (2003) Tissue-specific populations of leukocytes in semen-producing organs of the normal, hemicastrated, and vasectomized mouse. AIDS Res Hum Retrovir 19:235\u2013243","journal-title":"AIDS Res Hum Retrovir"},{"key":"2270_CR43","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.cell.2014.04.050","volume":"158","author":"PA Muller","year":"2014","unstructured":"Muller PA, Koscso B, Rajani GM, Stevanovic K, Berres ML, Hashimoto D, Mortha A, Leboeuf M, Li XM, Mucida D, Stanley ER, Dahan S, Margolis KG, Gershon MD, Merad M, Bogunovic M (2014) Crosstalk between muscularis macrophages and enteric neurons regulates gastrointestinal motility. Cell 158:300\u2013313","journal-title":"Cell"},{"key":"2270_CR44","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1365-2605.1989.tb01289.x","volume":"12","author":"D Nashan","year":"1989","unstructured":"Nashan D, Malorny U, Sorg C, Cooper T, Nieschlag E (1989) Immuno-competent cells in the murine epididymis. Int J Androl 12:85\u201394","journal-title":"Int J Androl"},{"key":"2270_CR45","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1097\/01.mog.0000231807.03149.54","volume":"22","author":"JH Niess","year":"2006","unstructured":"Niess JH, Reinecker HC (2006) Dendritic cells: the commanders-in-chief of mucosal immune defenses. Curr Opin Gastroenterol 22:354\u2013360","journal-title":"Curr Opin Gastroenterol"},{"key":"2270_CR46","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1126\/science.1102901","volume":"307","author":"JH Niess","year":"2005","unstructured":"Niess JH, Brand S, Gu X, Landsman L, Jung S, McCormick BA, Vyas JM, Boes M, Ploegh HL, Fox JG, Littman DR, Reinecker HC (2005) CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science 307:254\u2013258","journal-title":"Science"},{"key":"2270_CR47","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0165-0378(94)90019-1","volume":"26","author":"P Pollanen","year":"1994","unstructured":"Pollanen P, Cooper TG (1994) Immunology of the testicular excurrent ducts. J Reprod Immunol 26:167\u2013216","journal-title":"J Reprod Immunol"},{"key":"2270_CR48","doi-asserted-by":"crossref","first-page":"534","DOI":"10.3389\/fimmu.2014.00534","volume":"5","author":"KA Redgrove","year":"2014","unstructured":"Redgrove KA, McLaughlin EA (2014) The role of the immune response in Chlamydia trachomatis infection of the male genital tract: a double-edged sword. Front Immunol 5:534","journal-title":"Front Immunol"},{"key":"2270_CR49","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1146\/annurev-immunol-031210-101345","volume":"29","author":"B Reizis","year":"2011","unstructured":"Reizis B, Bunin A, Ghosh HS, Lewis KL, Sisirak V (2011a) Plasmacytoid dendritic cells: recent progress and open questions. Annu Rev Immunol 29:163\u2013183","journal-title":"Annu Rev Immunol"},{"key":"2270_CR50","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1038\/nri3027","volume":"11","author":"B Reizis","year":"2011","unstructured":"Reizis B, Colonna M, Trinchieri G, Barrat F, Gilliet M (2011b) Plasmacytoid dendritic cells: one-trick ponies or workhorses of the immune system? Nat Rev Immunol 11:558\u2013565","journal-title":"Nat Rev Immunol"},{"key":"2270_CR51","unstructured":"Robaire B, Hermo L (1988) Efferent ducts, epididymis, and vas deferens: structure, functions, and their regulation. In: Knobil E, Neill J (eds) The physiology of reproduction, vol 1, 2nd edn. Raven, New York, 99\u20131080"},{"key":"2270_CR52","series-title":"A comprehensive survey of the efferent ducts, the epididymis and the vas deferens","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4615-0679-9","volume-title":"The epididymis: from molecular to clinical practice","author":"B Robaire","year":"2002","unstructured":"Robaire B, Hinton BT (2002) The epididymis: from molecular to clinical practice. A comprehensive survey of the efferent ducts, the epididymis and the vas deferens. Kluwer Academic\/Plenum, New York"},{"key":"2270_CR53","first-page":"1072","volume-title":"Knobil and Neill's physiology of reproduction","author":"B Robaire","year":"2006","unstructured":"Robaire B, Hinton BT, Orgebin-Crist MC (2006) The epididymis. In: Neill JD (ed) Knobil and Neill's physiology of reproduction, vol 1. Elsevier Academic, Amsterdam, pp 1072\u20131148"},{"key":"2270_CR54","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1046\/j.1365-2605.1998.00116.x","volume":"21","author":"P Seiler","year":"1998","unstructured":"Seiler P, Wenzel I, Wagenfeld A, Yeung CH, Nieschlag E, Cooper TG (1998) The appearance of basal cells in the developing murine epididymis and their temporal expression of macrophage antigens. Int J Androl 21:217\u2013226","journal-title":"Int J Androl"},{"key":"2270_CR55","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1002\/j.1939-4640.1999.tb03379.x","volume":"20","author":"P Seiler","year":"1999","unstructured":"Seiler P, Cooper TG, Yeung CH, Nieschlag E (1999) Regional variation in macrophage antigen expression by murine epididymal basal cells and their regulation by testicular factors. J Androl 20:738\u2013746","journal-title":"J Androl"},{"key":"2270_CR56","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1046\/j.1365-2605.2000.00210.x","volume":"23","author":"P Seiler","year":"2000","unstructured":"Seiler P, Cooper TG, Nieschlag E (2000) Sperm number and condition affect the number of basal cells and their expression of macrophage antigen in the murine epididymis. Int J Androl 23:65\u201376","journal-title":"Int J Androl"},{"key":"2270_CR57","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1095\/biolreprod61.3.705","volume":"61","author":"V Serre","year":"1999","unstructured":"Serre V, Robaire B (1999) Distribution of immune cells in the epididymis of the aging brown Norway rat is segment-specific and related to the luminal content. Biol Reprod 61:705\u2013714","journal-title":"Biol Reprod"},{"key":"2270_CR58","first-page":"219","volume-title":"The epididymis: from molecular to clinical practice. A comprehensive survey of the efferent ducts, the epididymis and the vas deferens","author":"V Serre","year":"2002","unstructured":"Serre V, Robaire B (2002) Interactions of the immune system and the epididymis. In: Robaire B, Hinton BT (eds) The epididymis: from molecular to clinical practice. A comprehensive survey of the efferent ducts, the epididymis and the vas deferens, vol 1. Kluwer Academic\/Plenum, New York, pp 219\u2013231"},{"key":"2270_CR59","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1242\/jeb.027284","volume":"212","author":"WW Shum","year":"2009","unstructured":"Shum WW, Da Silva N, Brown D, Breton S (2009) Regulation of luminal acidification in the male reproductive tract via cell-cell crosstalk. J Exp Biol 212:1753\u20131761","journal-title":"J Exp Biol"},{"key":"2270_CR60","doi-asserted-by":"crossref","first-page":"576","DOI":"10.2164\/jandrol.111.012971","volume":"32","author":"WW Shum","year":"2011","unstructured":"Shum WW, Ruan YC, Da Silva N, Breton S (2011) Establishment of cell-cell cross talk in the epididymis: control of luminal acidification. J Androl 32:576\u2013586","journal-title":"J Androl"},{"key":"2270_CR61","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1095\/biolreprod.113.116681","volume":"90","author":"WW Shum","year":"2014","unstructured":"Shum WW, Smith TB, Cortez-Retamozo V, Grigoryeva LS, Roy JW, Hill E, Pittet MJ, Breton S, Da Silva N (2014) Epithelial basal cells are distinct from dendritic cells and macrophages in the mouse epididymis. Biol Reprod 90:90","journal-title":"Biol Reprod"},{"key":"2270_CR62","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1111\/j.2047-2927.2014.00251.x","volume":"2","author":"TB Smith","year":"2014","unstructured":"Smith TB, Cortez-Retamozo V, Grigoryeva LS, Hill E, Pittet MJ, Da Silva N (2014) Mononuclear phagocytes rapidly clear apoptotic epithelial cells in the proximal epididymis. Andrology 2:755\u2013762","journal-title":"Andrology"},{"key":"2270_CR63","first-page":"Suppl p\u00a046","volume-title":"Andrology. Handbook from the American Society of Andrology meeting, 18\u201321 April 2015, Salt Lake City, USA","author":"T Smith","year":"2015","unstructured":"Smith T, Courties G, Barton C, Nahrendorf M, Da Silva N (2015) Macrophages and dendritic cells cooperate to survey the epididymal lumen. In: Rajpert-DeMayts E, Carrell T (eds) Andrology. Handbook from the American Society of Andrology meeting, 18\u201321 April 2015, Salt Lake City, USA. American Society of Andrology, Schaumburg, Suppl p\u00a046"},{"key":"2270_CR64","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1002\/jemt.10319","volume":"61","author":"P Sutovsky","year":"2003","unstructured":"Sutovsky P (2003) Ubiquitin-dependent proteolysis in mammalian spermatogenesis, fertilization, and sperm quality control: killing three birds with one stone. Microsc Res Tech 61:88\u2013102","journal-title":"Microsc Res Tech"},{"key":"2270_CR65","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1242\/jcs.114.9.1665","volume":"114","author":"P Sutovsky","year":"2001","unstructured":"Sutovsky P, Moreno R, Ramalho-Santos J, Dominko T, Thompson WE, Schatten G (2001) A putative, ubiquitin-dependent mechanism for the recognition and elimination of defective spermatozoa in the mammalian epididymis. J Cell Sci 114:1665\u20131675","journal-title":"J Cell Sci"},{"key":"2270_CR66","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1002\/mrd.10101","volume":"61","author":"P Sutovsky","year":"2002","unstructured":"Sutovsky P, Neuber E, Schatten G (2002) Ubiquitin-dependent sperm quality control mechanism recognizes spermatozoa with DNA defects as revealed by dual ubiquitin-TUNEL assay. Mol Reprod Dev 61:406\u2013413","journal-title":"Mol Reprod Dev"},{"key":"2270_CR67","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1002\/aja.1001630404","volume":"163","author":"F Suzuki","year":"1982","unstructured":"Suzuki F (1982) Microvasculature of the mouse testis and excurrent duct system. Am J Anat 163:309\u2013325","journal-title":"Am J Anat"},{"key":"2270_CR68","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1002\/j.1939-4640.1995.tb00532.x","volume":"16","author":"TT Turner","year":"1995","unstructured":"Turner TT (1995) On the epididymis and its role in the development of the fertile ejaculate. J Androl 16:292\u2013298","journal-title":"J Androl"},{"key":"2270_CR69","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1002\/(SICI)1098-2795(199906)53:2<188::AID-MRD8>3.0.CO;2-O","volume":"53","author":"TT Turner","year":"1999","unstructured":"Turner TT, Riley TA (1999) p53 independent, region-specific epithelial apoptosis is induced in the rat epididymis by deprivation of luminal factors. Mol Reprod Dev 53:188\u2013197","journal-title":"Mol Reprod Dev"},{"key":"2270_CR70","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1095\/biolreprod.106.059493","volume":"77","author":"TT Turner","year":"2007","unstructured":"Turner TT, Johnston DS, Finger JN, Jelinsky SA (2007) Differential gene expression among the proximal segments of the rat epididymis is lost after efferent duct ligation. Biol Reprod 77:165\u2013171","journal-title":"Biol Reprod"},{"key":"2270_CR71","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1095\/biolreprod50.4.917","volume":"50","author":"CH Yeung","year":"1994","unstructured":"Yeung CH, Nashan D, Sorg C, Oberpenning F, Schulze H, Nieschlag E, Cooper TG (1994) Basal cells of the human epididymis\u2014antigenic and ultrastructural similarities to tissue-fixed macrophages. Biol Reprod 50:917\u2013926","journal-title":"Biol Reprod"},{"key":"2270_CR72","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/aja.2012.20","volume":"14","author":"CH Yeung","year":"2012","unstructured":"Yeung CH, Wang K, Cooper TG (2012) Why are epididymal tumours so rare? Asian J Androl 14:465\u2013475","journal-title":"Asian J Androl"},{"key":"2270_CR73","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.immuni.2012.12.001","volume":"38","author":"S Yona","year":"2013","unstructured":"Yona S, Kim KW, Wolf Y, Mildner A, Varol D, Breker M, Strauss-Ayali D, Viukov S, Guilliams M, Misharin A, Hume DA, Perlman H, Malissen B, Zelzer E, Jung S (2013) Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity 38:79\u201391","journal-title":"Immunity"}],"container-title":["Cell and Tissue Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00441-015-2270-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00441-015-2270-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00441-015-2270-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T22:38:58Z","timestamp":1718059138000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00441-015-2270-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,4]]},"references-count":73,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["2270"],"URL":"https:\/\/doi.org\/10.1007\/s00441-015-2270-0","relation":{},"ISSN":["0302-766X","1432-0878"],"issn-type":[{"value":"0302-766X","type":"print"},{"value":"1432-0878","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,4]]}}}