{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T18:44:55Z","timestamp":1766515495672,"version":"3.37.3"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2015,12,28]],"date-time":"2015-12-28T00:00:00Z","timestamp":1451260800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2015,12,28]],"date-time":"2015-12-28T00:00:00Z","timestamp":1451260800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AR44745","GM55625"],"award-info":[{"award-number":["AR44745","GM55625"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell Tissue Res"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1007\/s00441-015-2346-x","type":"journal-article","created":{"date-parts":[[2015,12,28]],"date-time":"2015-12-28T05:47:11Z","timestamp":1451281631000},"page":"637-646","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Forelimb contractures and abnormal tendon collagen fibrillogenesis in fibulin-4 null mice"],"prefix":"10.1007","volume":"364","author":[{"given":"Dessislava Z.","family":"Markova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Te-Cheng","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui-Zhu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guiyun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takako","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Machiko","family":"Arita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David E.","family":"Birk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mon-Li","family":"Chu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,12,28]]},"reference":[{"key":"2346_CR1","doi-asserted-by":"publisher","first-page":"1677","DOI":"10.1016\/j.amjcard.2012.01.394","volume":"109","author":"ZN Al-Hassnan","year":"2012","unstructured":"Al-Hassnan ZN, Almesned AR, Tulbah S, Hakami A, Al-Omrani A, Al Sehly A, Mohammed S, Majid S, Meyer B, Al-Fayyadh M (2012) Recessively inherited severe aortic aneurysm caused by mutated EFEMP2. Am J Cardiol 109:1677\u20131680","journal-title":"Am J Cardiol"},{"key":"2346_CR2","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1083\/jcb.200105046","volume":"154","author":"E Arteaga-Solis","year":"2001","unstructured":"Arteaga-Solis E, Gayraud B, Lee SY, Shum L, Sakai L, Ramirez F (2001) Regulation of limb patterning by extracellular microfibrils. J Cell Biol 154:275\u2013281","journal-title":"J Cell Biol"},{"key":"2346_CR3","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1016\/j.matbio.2008.09.579","volume":"27","author":"R Boregowda","year":"2008","unstructured":"Boregowda R, Paul E, White J, Ritty TM (2008) Bone and soft connective tissue alterations result from loss of fibrillin-2 expression. Matrix Biol 27:661\u2013666","journal-title":"Matrix Biol"},{"key":"2346_CR4","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1002\/humu.22165","volume":"34","author":"B Callewaert","year":"2013","unstructured":"Callewaert B, Su CT, Van Damme T, Vlummens P, Malfait F, Vanakker O, Schulz B, Mac Neal M, Davis EC, Lee JG, Salhi A, Unger S, Heimdal K, De Almeida S, Kornak U, Gaspar H, Bresson JL, Prescott K, Gosendi ME, Mansour S, Pierard GE, Madan-Khetarpal S, Sciurba FC, Symoens S, Coucke PJ, Van Maldergem L, Urban Z, De Paepe A (2013) Comprehensive clinical and molecular analysis of 12 families with type 1 recessive cutis laxa. Hum Mutat 34:111\u2013121","journal-title":"Hum Mutat"},{"key":"2346_CR5","doi-asserted-by":"publisher","first-page":"24553","DOI":"10.1074\/jbc.M109.019364","volume":"284","author":"R Choudhury","year":"2009","unstructured":"Choudhury R, McGovern A, Ridley C, Cain SA, Baldwin A, Wang MC, Guo C, Mironov A Jr, Drymoussi Z, Trump D, Shuttleworth A, Baldock C, Kielty CM (2009) Differential regulation of elastic fiber formation by fibulin-4 and -5. J Biol Chem 284:24553\u201324567","journal-title":"J Biol Chem"},{"key":"2346_CR6","doi-asserted-by":"publisher","first-page":"2635","DOI":"10.1002\/ajmg.a.31980","volume":"143A","author":"M Dasouki","year":"2007","unstructured":"Dasouki M, Markova D, Garola R, Sasaki T, Charbonneau NL, Sakai LY, Chu ML (2007) Compound heterozygous mutations in fibulin-4 causing neonatal lethal pulmonary artery occlusion, aortic aneurysm, arachnodactyly, and mild cutis laxa. Am J Med Genet A 143A:2635\u20132641","journal-title":"Am J Med Genet A"},{"key":"2346_CR7","doi-asserted-by":"publisher","first-page":"1890","DOI":"10.1007\/s00018-009-8632-6","volume":"66","author":"S de Vega","year":"2009","unstructured":"de Vega S, Iwamoto T, Yamada Y (2009) Fibulins: multiple roles in matrix structures and tissue functions. Cell Mol Life Sci 66:1890\u20131902","journal-title":"Cell Mol Life Sci"},{"key":"2346_CR8","doi-asserted-by":"publisher","first-page":"8935","DOI":"10.1074\/jbc.M608204200","volume":"282","author":"E El-Hallous","year":"2007","unstructured":"El-Hallous E, Sasaki T, Hubmacher D, Getie M, Tiedemann K, Brinckmann J, Batge B, Davis EC, Reinhardt DP (2007) Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin. J Biol Chem 282:8935\u20138946","journal-title":"J Biol Chem"},{"key":"2346_CR9","doi-asserted-by":"publisher","first-page":"137","DOI":"10.2350\/11-03-1010-CR.1","volume":"15","author":"LK Erickson","year":"2012","unstructured":"Erickson LK, Opitz JM, Zhou H (2012) Lethal osteogenesis imperfecta-like condition with cutis laxa and arterial tortuosity in MZ twins due to a homozygous fibulin-4 mutation. Pediatr Dev Pathol 15:137\u2013141","journal-title":"Pediatr Dev Pathol"},{"key":"2346_CR10","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1111\/joa.12048","volume":"222","author":"TM Grant","year":"2013","unstructured":"Grant TM, Thompson MS, Urban J, Yu J (2013) Elastic fibres are broadly distributed in tendon and highly localized around tenocytes. J Anat 222:573\u2013579","journal-title":"J Anat"},{"key":"2346_CR11","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1161\/01.RES.0000260181.19449.95","volume":"100","author":"K Hanada","year":"2007","unstructured":"Hanada K, Vermeij M, Garinis GA, de Waard MC, Kunen MG, Myers L, Maas A, Duncker DJ, Meijers C, Dietz HC, Kanaar R, Essers J (2007) Perturbations of vascular homeostasis and aortic valve abnormalities in fibulin-4 deficient mice. Circ Res 100:738\u2013746","journal-title":"Circ Res"},{"key":"2346_CR12","first-page":"671","volume":"173","author":"C Hebson","year":"2014","unstructured":"Hebson C, Coleman K, Clabby M, Sallee D, Shankar S, Loeys B, Van Laer L, Kogon B (2014) Severe aortopathy due to fibulin-4 deficiency: molecular insights, surgical strategy, and a review of the literature. Eur J Pediatr 173:671\u2013675","journal-title":"Eur J Pediatr"},{"key":"2346_CR13","doi-asserted-by":"publisher","first-page":"19029","DOI":"10.1073\/pnas.0908268106","volume":"106","author":"M Horiguchi","year":"2009","unstructured":"Horiguchi M, Inoue T, Ohbayashi T, Hirai M, Noda K, Marmorstein LY, Yabe D, Takagi K, Akama TO, Kita T, Kimura T, Nakamura T (2009) Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase. Proc Natl Acad Sci U S A 106:19029\u201319034","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2346_CR14","doi-asserted-by":"publisher","first-page":"14387","DOI":"10.1074\/jbc.M210144200","volume":"278","author":"IK Hornstra","year":"2003","unstructured":"Hornstra IK, Birge S, Starcher B, Bailey AJ, Mecham RP, Shapiro SD (2003) Lysyl oxidase is required for vascular and diaphragmatic development in mice. J Biol Chem 278:14387\u201314393","journal-title":"J Biol Chem"},{"key":"2346_CR15","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1111\/j.1399-0004.2009.01204.x","volume":"76","author":"J Hoyer","year":"2009","unstructured":"Hoyer J, Kraus C, Hammersen G, Geppert JP, Rauch A (2009) Lethal cutis laxa with contractural arachnodactyly, overgrowth and soft tissue bleeding due to a novel homozygous fibulin-4 gene mutation. Clin Genet 76:276\u2013281","journal-title":"Clin Genet"},{"key":"2346_CR16","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1161\/CIRCRESAHA.109.207852","volume":"106","author":"J Huang","year":"2010","unstructured":"Huang J, Davis EC, Chapman SL, Budatha M, Marmorstein LY, Word RA, Yanagisawa H (2010) Fibulin-4 deficiency results in ascending aortic aneurysms: a potential link between abnormal smooth muscle cell phenotype and aneurysm progression. Circ Res 106:583\u2013592","journal-title":"Circ Res"},{"key":"2346_CR17","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.1086\/504304","volume":"78","author":"V Hucthagowder","year":"2006","unstructured":"Hucthagowder V, Sausgruber N, Kim KH, Angle B, Marmorstein LY, Urban Z (2006) Fibulin-4: a novel gene for an autosomal recessive cutis laxa syndrome. Am J Hum Genet 78:1075\u20131080","journal-title":"Am J Hum Genet"},{"key":"2346_CR18","doi-asserted-by":"publisher","first-page":"2764","DOI":"10.1161\/CIRCULATIONAHA.112.119883","volume":"126","author":"M Iascone","year":"2012","unstructured":"Iascone M, Sana ME, Pezzoli L, Bianchi P, Marchetti D, Fasolini G, Sadou Y, Locatelli A, Fabiani F, Mangili G, Ferrazzi P (2012) Extensive arterial tortuosity and severe aortic dilation in a newborn with an EFEMP2 mutation. Circulation 126:2764\u20132768","journal-title":"Circulation"},{"key":"2346_CR19","doi-asserted-by":"publisher","first-page":"21443","DOI":"10.1074\/jbc.M115.640425","volume":"290","author":"O Igoucheva","year":"2015","unstructured":"Igoucheva O, Alexeev V, Halabi CM, Adams SM, Stoilov I, Sasaki T, Arita M, Donahue A, Mecham RP, Birk DE, Chu ML (2015) Fibulin-4 E57K knock-in mice recapitulate cutaneous, vascular and skeletal defects of recessive cutis laxa 1B with both elastic fiber and collagen fibril abnormalities. J Biol Chem 290:21443\u201321459","journal-title":"J Biol Chem"},{"key":"2346_CR20","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.matbio.2010.10.001","volume":"30","author":"Y Izu","year":"2011","unstructured":"Izu Y, Ansorge HL, Zhang G, Soslowsky LJ, Bonaldo P, Chu ML, Birk DE (2011) Dysfunctional tendon collagen fibrillogenesis in collagen VI null mice. Matrix Biol 30:53\u201361","journal-title":"Matrix Biol"},{"key":"2346_CR21","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1186\/1750-1172-7-61","volume":"7","author":"M Kappanayil","year":"2012","unstructured":"Kappanayil M, Nampoothiri S, Kannan R, Renard M, Coucke P, Malfait F, Menon S, Ravindran HK, Kurup R, Faiyaz-Ul-Haque M, Kumar K, De Paepe A (2012) Characterization of a distinct lethal arteriopathy syndrome in twenty-two infants associated with an identical, novel mutation in FBLN4 gene, confirms fibulin-4 as a critical determinant of human vascular elastogenesis. Orphanet J Rare Dis 7:61","journal-title":"Orphanet J Rare Dis"},{"key":"2346_CR22","doi-asserted-by":"publisher","first-page":"11805","DOI":"10.1074\/jbc.M611029200","volume":"282","author":"N Kobayashi","year":"2007","unstructured":"Kobayashi N, Kostka G, Garbe JH, Keene DR, Bachinger HP, Hanisch FG, Markova D, Tsuda T, Timpl R, Chu ML, Sasaki T (2007) A comparative analysis of the fibulin protein family. Biochemical characterization, binding interactions, and tissue localization. J Biol Chem 282:11805\u201311816","journal-title":"J Biol Chem"},{"key":"2346_CR23","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1242\/dev.113449","volume":"142","author":"L Kutchuk","year":"2015","unstructured":"Kutchuk L, Laitala A, Soueid-Bomgarten S, Shentzer P, Rosendahl AH, Eilot S, Grossman M, Sagi I, Sormunen R, Myllyharju J, Maki JM, Hasson P (2015) Muscle composition is regulated by a Lox-TGFbeta feedback loop. Development 142:983\u2013993","journal-title":"Development"},{"key":"2346_CR24","doi-asserted-by":"publisher","first-page":"2113","DOI":"10.1093\/hmg\/11.18.2113","volume":"11","author":"B Loeys","year":"2002","unstructured":"Loeys B, Van Maldergem L, Mortier G, Coucke P, Gerniers S, Naeyaert JM, De Paepe A (2002) Homozygosity for a missense mutation in fibulin-5 (FBLN5) results in a severe form of cutis laxa. Hum Mol Genet 11:2113\u20132118","journal-title":"Hum Mol Genet"},{"key":"2346_CR25","doi-asserted-by":"publisher","first-page":"2304","DOI":"10.1007\/s00018-006-6149-9","volume":"63","author":"HA Lucero","year":"2006","unstructured":"Lucero HA, Kagan HM (2006) Lysyl oxidase: an oxidative enzyme and effector of cell function. Cell Mol Life Sci 63:2304\u20132316","journal-title":"Cell Mol Life Sci"},{"key":"2346_CR26","doi-asserted-by":"publisher","first-page":"2503","DOI":"10.1161\/01.CIR.0000038109.84500.1E","volume":"106","author":"JM Maki","year":"2002","unstructured":"Maki JM, Rasanen J, Tikkanen H, Sormunen R, Makikallio K, Kivirikko KI, Soininen R (2002) Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice. Circulation 106:2503\u20132509","journal-title":"Circulation"},{"key":"2346_CR27","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1016\/S0002-9440(10)61183-2","volume":"167","author":"JM Maki","year":"2005","unstructured":"Maki JM, Sormunen R, Lippo S, Kaarteenaho-Wiik R, Soininen R, Myllyharju J (2005) Lysyl oxidase is essential for normal development and function of the respiratory system and for the integrity of elastic and collagen fibers in various tissues. Am J Pathol 167:927\u2013936","journal-title":"Am J Pathol"},{"key":"2346_CR28","doi-asserted-by":"publisher","first-page":"3006","DOI":"10.1242\/jcs.073437","volume":"123","author":"T Massam-Wu","year":"2010","unstructured":"Massam-Wu T, Chiu M, Choudhury R, Chaudhry SS, Baldwin AK, McGovern A, Baldock C, Shuttleworth CA, Kielty CM (2010) Assembly of fibrillin microfibrils governs extracellular deposition of latent TGF beta. J Cell Sci 123:3006\u20133018","journal-title":"J Cell Sci"},{"key":"2346_CR29","doi-asserted-by":"publisher","first-page":"1700","DOI":"10.1128\/MCB.26.5.1700-1709.2006","volume":"26","author":"PJ McLaughlin","year":"2006","unstructured":"McLaughlin PJ, Chen Q, Horiguchi M, Starcher BC, Stanton JB, Broekelmann TJ, Marmorstein AD, McKay B, Mecham R, Nakamura T, Marmorstein LY (2006) Targeted disruption of fibulin-4 abolishes elastogenesis and causes perinatal lethality in mice. Mol Cell Biol 26:1700\u20131709","journal-title":"Mol Cell Biol"},{"key":"2346_CR30","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1038\/415171a","volume":"415","author":"T Nakamura","year":"2002","unstructured":"Nakamura T, Lozano PR, Ikeda Y, Iwanaga Y, Hinek A, Minamisawa S, Cheng CF, Kobuke K, Dalton N, Takada Y, Tashiro K, Ross J Jr, Honjo T, Chien KR (2002) Fibulin-5\/DANCE is essential for elastogenesis in vivo. Nature 415:171\u2013175","journal-title":"Nature"},{"key":"2346_CR31","doi-asserted-by":"publisher","first-page":"16872","DOI":"10.1074\/jbc.M809348200","volume":"284","author":"RN Ono","year":"2009","unstructured":"Ono RN, Sengle G, Charbonneau NL, Carlberg V, Bachinger HP, Sasaki T, Lee-Arteaga S, Zilberberg L, Rifkin DB, Ramirez F, Chu ML, Sakai LY (2009) Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites. J Biol Chem 284:16872\u201316881","journal-title":"J Biol Chem"},{"key":"2346_CR32","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.matbio.2014.02.004","volume":"37","author":"CL Papke","year":"2014","unstructured":"Papke CL, Yanagisawa H (2014) Fibulin-4 and fibulin-5 in elastogenesis and beyond: insights from mouse and human studies. Matrix Biol 37:142\u2013149","journal-title":"Matrix Biol"},{"key":"2346_CR33","doi-asserted-by":"publisher","first-page":"5867","DOI":"10.1093\/hmg\/ddv308","volume":"24","author":"CL Papke","year":"2015","unstructured":"Papke CL, Tsunezumi J, Ringuette LJ, Nagaoka H, Terajima M, Yamashiro Y, Urquhart G, Yamauchi M, Davis EC, Yanagisawa H (2015) Loss of fibulin-4 disrupts collagen synthesis and maturation: implications for pathology resulting from EFEMP2 mutations. Hum Mol Genet 24:5867\u20135879","journal-title":"Hum Mol Genet"},{"key":"2346_CR34","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1242\/dev.027342","volume":"136","author":"BA Pryce","year":"2009","unstructured":"Pryce BA, Watson SS, Murchison ND, Staverosky JA, Dunker N, Schweitzer R (2009) Recruitment and maintenance of tendon progenitors by TGFbeta signaling are essential for tendon formation. Development 136:1351\u20131361","journal-title":"Development"},{"key":"2346_CR35","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/s00441-009-0822-x","volume":"339","author":"F Ramirez","year":"2010","unstructured":"Ramirez F, Sakai LY (2010) Biogenesis and function of fibrillin assemblies. Cell Tissue Res 339:71\u201382","journal-title":"Cell Tissue Res"},{"key":"2346_CR36","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1038\/ejhg.2010.45","volume":"18","author":"M Renard","year":"2010","unstructured":"Renard M, Holm T, Veith R, Callewaert BL, Ades LC, Baspinar O, Pickart A, Dasouki M, Hoyer J, Rauch A, Trapane P, Earing MG, Coucke PJ, Sakai LY, Dietz HC, De Paepe AM, Loeys BL (2010) Altered TGFbeta signaling and cardiovascular manifestations in patients with autosomal recessive cutis laxa type I caused by fibulin-4 deficiency. Eur J Hum Genet 18:895\u2013901","journal-title":"Eur J Hum Genet"},{"key":"2346_CR37","doi-asserted-by":"publisher","first-page":"1148","DOI":"10.1002\/ajmg.a.35827","volume":"161A","author":"SL Sawyer","year":"2013","unstructured":"Sawyer SL, Dicke F, Kirton A, Rajapkse T, Rebeyka IM, McInnes B, Parboosingh JS, Bernier FP (2013) Longer term survival of a child with autosomal recessive cutis laxa due to a mutation in FBLN4. Am J Med Genet A 161A:1148\u20131153","journal-title":"Am J Med Genet A"},{"key":"2346_CR38","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1005340","volume":"11","author":"G Sengle","year":"2015","unstructured":"Sengle G, Carlberg V, Tufa SF, Charbonneau NL, Smaldone S, Carlson EJ, Ramirez F, Keene DR, Sakai LY (2015) Abnormal activation of BMP signaling causes myopathy in Fbn2 null mice. PLoS Genet 11, e1005340","journal-title":"PLoS Genet"},{"key":"2346_CR39","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1038\/nrm1130","volume":"4","author":"R Timpl","year":"2003","unstructured":"Timpl R, Sasaki T, Kostka G, Chu ML (2003) Fibulins: a versatile family of extracellular matrix proteins. Nat Rev Mol Cell Biol 4:479\u2013489","journal-title":"Nat Rev Mol Cell Biol"},{"key":"2346_CR40","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.matbio.2013.07.006","volume":"33","author":"Z Urban","year":"2014","unstructured":"Urban Z, Davis EC (2014) Cutis laxa: intersection of elastic fiber biogenesis, TGFbeta signaling, the secretory pathway and metabolism. Matrix Biol 33:16\u201322","journal-title":"Matrix Biol"},{"key":"2346_CR41","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1002\/bdrc.20111","volume":"81","author":"JE Wagenseil","year":"2007","unstructured":"Wagenseil JE, Mecham RP (2007) New insights into elastic fiber assembly. Birth Defects Res C Embryol Today 81:229\u2013240","journal-title":"Birth Defects Res C Embryol Today"},{"key":"2346_CR42","doi-asserted-by":"publisher","first-page":"1084","DOI":"10.1016\/j.biocel.2010.03.009","volume":"42","author":"H Yanagisawa","year":"2010","unstructured":"Yanagisawa H, Davis EC (2010) Unraveling the mechanism of elastic fiber assembly: the roles of short fibulins. Int J Biochem Cell Biol 42:1084\u20131093","journal-title":"Int J Biochem Cell Biol"},{"key":"2346_CR43","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1038\/415168a","volume":"415","author":"H Yanagisawa","year":"2002","unstructured":"Yanagisawa H, Davis EC, Starcher BC, Ouchi T, Yanagisawa M, Richardson JA, Olson EN (2002) Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo. Nature 415:168\u2013171","journal-title":"Nature"}],"container-title":["Cell and Tissue Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00441-015-2346-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00441-015-2346-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00441-015-2346-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00441-015-2346-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,16]],"date-time":"2020-05-16T14:21:06Z","timestamp":1589638866000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00441-015-2346-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,28]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["2346"],"URL":"https:\/\/doi.org\/10.1007\/s00441-015-2346-x","relation":{},"ISSN":["0302-766X","1432-0878"],"issn-type":[{"type":"print","value":"0302-766X"},{"type":"electronic","value":"1432-0878"}],"subject":[],"published":{"date-parts":[[2015,12,28]]},"assertion":[{"value":"4 August 2015","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 December 2015","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 December 2015","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}