{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T08:08:44Z","timestamp":1790842124452,"version":"4.1.0"},"reference-count":87,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2021,9,22]],"date-time":"2021-09-22T00:00:00Z","timestamp":1632268800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2021,9,22]],"date-time":"2021-09-22T00:00:00Z","timestamp":1632268800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell Tissue Res"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1007\/s00441-021-03523-7","type":"journal-article","created":{"date-parts":[[2021,9,22]],"date-time":"2021-09-22T04:02:47Z","timestamp":1632283367000},"page":"227-237","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["New insights into the role and origin of pituitary S100\u03b2-positive cells"],"prefix":"10.1007","volume":"386","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6974-9891","authenticated-orcid":false,"given":"Yukio","family":"Kato","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saishu","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takako","family":"Kato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,9,22]]},"reference":[{"key":"3523_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1530\/eje.1.01949","volume":"153","author":"W Allaerts","year":"2005","unstructured":"Allaerts W, Vankelecom H (2005) History and perspectives of pituitary folliculo-stellate cell research. Eur J Endocrinol 153:1\u201312","journal-title":"Eur J Endocrinol"},{"key":"3523_CR2","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/j.stem.2013.07.004","volume":"13","author":"CL Andoniadou","year":"2013","unstructured":"Andoniadou CL, Matsushima D, Mousavy Gharavy SN, Signore M, Mackintosh AI, Schaeffer M, Gaston-Massuet C, Mollard P, Jacques TS, Le Tissier P, Dattani MT, Pevny LH, Martinez-Barbera JP (2013) Sox2(+) stem\/progenitor cells in the adult mouse pituitary support organ homeostasis and have tumor-inducing potential. Cell Stem Cell 13:433\u2013445","journal-title":"Cell Stem Cell"},{"key":"3523_CR3","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1016\/j.expneurol.2005.12.015","volume":"198","author":"JB Aquino","year":"2006","unstructured":"Aquino JB, Hjerling-Leffler J, Koltzenburg M, Edlund T, Villar MJ, Ernfors P (2006) In vitro and in vivo differentiation of boundary cap neural crest stem cells into mature Schwann cells. Exp Neurol 198:438\u2013449","journal-title":"Exp Neurol"},{"key":"3523_CR4","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1007\/s11914-018-0458-4","volume":"16","author":"BC Bragdon","year":"2018","unstructured":"Bragdon BC, Bahney CS (2018) Origin of reparative stem cells in fracture healing. Curr Osteoporos Rep 16:490\u2013503","journal-title":"Curr Osteoporos Rep"},{"key":"3523_CR5","doi-asserted-by":"publisher","first-page":"3293","DOI":"10.1210\/me.2006-0293","volume":"20","author":"J Chen","year":"2006","unstructured":"Chen J, Crabbe A, Van Duppen V, Vankelecom H (2006) The notch signaling system is present in the postnatal pituitary: marked expression and regulatory activity in the newly discovered side population. Mol Endocrinol 20:3293\u20133307","journal-title":"Mol Endocrinol"},{"key":"3523_CR6","doi-asserted-by":"publisher","first-page":"3985","DOI":"10.1210\/en.2005-0185","volume":"146","author":"J Chen","year":"2005","unstructured":"Chen J, Hersmus N, Van Duppen V, Caesens P, Denef C, Vankelecom H (2005) The adult pituitary contains a cell population displaying stem\/progenitor cell and early embryonic characteristics. Endocrinology 146:3985\u20133998","journal-title":"Endocrinology"},{"key":"3523_CR7","doi-asserted-by":"publisher","first-page":"3603","DOI":"10.1210\/endo.141.10.7710","volume":"141","author":"L Chen","year":"2000","unstructured":"Chen L, Maruyama D, Sugiyama M, Sakai T, Mogi C, Kato M, Kurotani R, Shirasawa N, Takaki A, Renner U, Kato Y, Inoue K (2000) Cytological characterization of a pituitary folliculo-stellate-like cell line, Tpit\/F1, with special reference to adenosine triphosphate-mediated neural nitric oxide synthetase expression and nitric oxide secretion. Endocrinology 141:3603\u20133610","journal-title":"Endocrinology"},{"key":"3523_CR8","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1007\/s00441-013-1713-8","volume":"354","author":"M Chen","year":"2013","unstructured":"Chen M, Kato T, Higuchi M, Yoshida S, Yako H, Kanno N, Kato Y (2013) Coxsackievirus and adenovirus receptor-positive cells compose the putative stem\/progenitor cell niches in the marginal cell layer and parenchyma of the rat anterior pituitary. Cell Tissue Res 354:823\u2013836","journal-title":"Cell Tissue Res"},{"key":"3523_CR9","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1007\/BF01205018","volume":"9","author":"D Cocchia","year":"1980","unstructured":"Cocchia D, Miani N (1980) Immunocytochemical localization of the brain-specific S-100 protein in the pituitary gland of adult rat. J Neurocytol 9:771\u2013782","journal-title":"J Neurocytol"},{"key":"3523_CR10","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1016\/0012-1606(85)90101-0","volume":"110","author":"GF Couly","year":"1985","unstructured":"Couly GF, Le Douarin NM (1985) Mapping of the early neural primordium in quail-chick chimeras. I. Developmental relationships between placodes, facial ectoderm, and prosencephalon. Dev Biol 110:422\u2013439","journal-title":"Dev Biol"},{"key":"3523_CR11","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1016\/0012-1606(87)90118-7","volume":"120","author":"GF Couly","year":"1987","unstructured":"Couly GF, Le Douarin NM (1987) Mapping of the early neural primordium in quail-chick chimeras. II. The prosencephalic neural plate and neural folds: implications for the genesis of cephalic human congenital abnormalities. Dev Biol 120:198\u2013214","journal-title":"Dev Biol"},{"key":"3523_CR12","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1679\/aohc1950.44.103","volume":"44","author":"S Daikoku","year":"1981","unstructured":"Daikoku S, Kawano H, Abe K, Yoshinaga K (1981) Topographical appearance of adenohypophysial cells with special reference to the development of the portal system. Arch Histol Jpn 44:103\u2013116","journal-title":"Arch Histol Jpn"},{"key":"3523_CR13","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/j.tips.2014.06.006","volume":"35","author":"FM Davis","year":"2014","unstructured":"Davis FM, Stewart TA, Thompson EW, Monteith GR (2014) Targeting EMT in cancer: opportunities for pharmacological intervention. Trends Pharmacol Sci 35:479\u2013488","journal-title":"Trends Pharmacol Sci"},{"key":"3523_CR14","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/s12861-016-0118-9","volume":"16","author":"SW Davis","year":"2016","unstructured":"Davis SW, Mortensen AH, Keisler JL, Zacharias AL, Gage PJ, Yamamura K, Camper SA (2016) beta-catenin is required in the neural crest and mesencephalon for pituitary gland organogenesis. BMC Dev Biol 16:16","journal-title":"BMC Dev Biol"},{"key":"3523_CR15","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1111\/j.1365-2826.2008.01716.x","volume":"20","author":"S Devnath","year":"2008","unstructured":"Devnath S, Inoue K (2008) An insight to pituitary folliculo-stellate cells. J Neuroendocrinol 20:687\u2013691","journal-title":"J Neuroendocrinol"},{"key":"3523_CR16","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1016\/j.bbamcr.2008.11.009","volume":"1793","author":"R Donato","year":"2009","unstructured":"Donato R, Sorci G, Riuzzi F, Arcuri C, Bianchi R, Brozzi F, Tubaro C, Giambanco I (2009) S100B\u2019s double life: intracellular regulator and extracellular signal. Biochim Biophys Acta 1793:1008\u20131022","journal-title":"Biochim Biophys Acta"},{"key":"3523_CR17","doi-asserted-by":"publisher","first-page":"2907","DOI":"10.1073\/pnas.0707886105","volume":"105","author":"T Fauquier","year":"2008","unstructured":"Fauquier T, Rizzoti K, Dattani M, Lovell-Badge R, Robinson IC (2008) SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland. Proc Natl Acad Sci USA 105:2907\u20132912","journal-title":"Proc Natl Acad Sci USA"},{"key":"3523_CR18","doi-asserted-by":"crossref","unstructured":"Fujiwara S, Hoshikawa S, Ueno T, Hirata M, Saito T, Ikeda T, Kawaguchi H, Nakamura K, Tanaka S, Ogata T (2014) SOX10 transactivates S100B to suppress Schwann cell proliferation and to promote myelination. PLoS One 9:e115400","DOI":"10.1371\/journal.pone.0115400"},{"key":"3523_CR19","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1007\/s00441-020-03200-1","volume":"381","author":"K Fujiwara","year":"2020","unstructured":"Fujiwara K, Tsukada T, Horiguchi K, Fujiwara Y, Takemoto K, Nio-Kobayashi J, Ohno N, Inoue K (2020) Aldolase C is a novel molecular marker for folliculo-stellate cells in rodent pituitary. Cell Tissue Res 381:273\u2013284","journal-title":"Cell Tissue Res"},{"key":"3523_CR20","doi-asserted-by":"publisher","first-page":"6332","DOI":"10.1073\/pnas.0801644105","volume":"105","author":"AS Gleiberman","year":"2008","unstructured":"Gleiberman AS, Michurina T, Encinas JM, Roig JL, Krasnov P, Balordi F, Fishell G, Rosenfeld MG, Enikolopov G (2008) Genetic approaches identify adult pituitary stem cells. Proc Natl Acad Sci USA 105:6332\u20136337","journal-title":"Proc Natl Acad Sci USA"},{"key":"3523_CR21","first-page":"2376","volume":"143","author":"S Goldsmith","year":"2016","unstructured":"Goldsmith S, Lovell-Badge R, Rizzoti K (2016) SOX2 is sequentially required for progenitor proliferation and lineage specification in the developing pituitary. Development (cambridge, England) 143:2376\u20132388","journal-title":"Development (cambridge, England)"},{"key":"3523_CR22","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1089\/scd.2011.0496","volume":"21","author":"L Gremeaux","year":"2012","unstructured":"Gremeaux L, Fu Q, Chen J, Vankelecom H (2012) Activated phenotype of the pituitary stem\/progenitor cell compartment during the early-postnatal maturation phase of the gland. Stem Cells Dev 21:801\u2013813","journal-title":"Stem Cells Dev"},{"key":"3523_CR23","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1007\/s00441-014-1890-0","volume":"357","author":"M Higuchi","year":"2014","unstructured":"Higuchi M, Kanno N, Yoshida S, Ueharu H, Chen M, Yako H, Shibuya S, Sekita M, Tsuda M, Mitsuishi H, Kato T, Kato Y (2014) GFP-expressing S100\u03b2-positive cells of the rat anterior pituitary differentiate into hormone-producing cells. Cell Tissue Res 357:767\u2013779","journal-title":"Cell Tissue Res"},{"key":"3523_CR24","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1007\/s00441-017-2603-2","volume":"369","author":"M Higuchi","year":"2017","unstructured":"Higuchi M, Yoshida S, Kanno N, Mitsuishi H, Ueharu H, Chen M, Nishimura N, Kato T, Kato Y (2017) Clump formation in mouse pituitary-derived non-endocrine cell line Tpit\/F1 promotes differentiation into growth-hormone-producing cells. Cell Tissue Res 369:353\u2013368","journal-title":"Cell Tissue Res"},{"key":"3523_CR25","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1007\/s00441-015-2128-5","volume":"361","author":"M Higuchi","year":"2015","unstructured":"Higuchi M, Yoshida S, Ueharu H, Chen M, Kato T, Kato Y (2015) PRRX1- and PRRX2-positive mesenchymal stem\/progenitor cells are involved in vasculogenesis during rat embryonic pituitary development. Cell Tissue Res 361:557\u2013565","journal-title":"Cell Tissue Res"},{"key":"3523_CR26","doi-asserted-by":"publisher","first-page":"5533","DOI":"10.1038\/s41598-018-23923-0","volume":"8","author":"K Horiguchi","year":"2018","unstructured":"Horiguchi K, Fujiwara K, Yoshida S, Nakakura T, Arae K, Tsukada T, Hasegawa R, Takigami S, Ohsako S, Yashiro T, Kato T, Kato Y (2018) Isolation and characterisation of CD9-positive pituitary adult stem\/progenitor cells in rats. Sci Rep 8:5533","journal-title":"Sci Rep"},{"key":"3523_CR27","doi-asserted-by":"crossref","unstructured":"Horiguchi K, Yako H, Yoshida S, Fujiwara K, Tsukada T, Kanno N, Ueharu H, Nishihara H, Kato T, Yashiro T, Kato Y (2016) S100\u03b2-positive cells of mesenchymal origin reside in the anterior lobe of the embryonic pituitary gland. PLoS One 11:e0163981","DOI":"10.1371\/journal.pone.0163981"},{"key":"3523_CR28","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1007\/s00418-020-01943-0","volume":"155","author":"K Horiguchi","year":"2021","unstructured":"Horiguchi K, Yoshida S, Tsukada T, Fujiwara K, Nakakura T, Hasegawa R, Takigami S, Ohsako S (2021) Cluster of differentiation (CD) 9-positive mouse pituitary cells are adult stem\/progenitor cells. Histochem Cell Biol 155:391\u2013404","journal-title":"Histochem Cell Biol"},{"key":"3523_CR29","doi-asserted-by":"publisher","first-page":"1518","DOI":"10.1210\/en.2006-1390","volume":"148","author":"E Itakura","year":"2007","unstructured":"Itakura E, Odaira K, Yokoyama K, Osuna M, Hara T, Inoue K (2007) Generation of transgenic rats expressing green fluorescent protein in S-100beta-producing pituitary folliculo-stellate cells and brain astrocytes. Endocrinology 148:1518\u20131523","journal-title":"Endocrinology"},{"key":"3523_CR30","doi-asserted-by":"publisher","first-page":"3635","DOI":"10.1172\/JCI64311","volume":"122","author":"SA Jayakody","year":"2012","unstructured":"Jayakody SA, Andoniadou CL, Gaston-Massuet C, Signore M, Cariboni A, Bouloux PM, Le Tissier P, Pevny LH, Dattani MT, Martinez-Barbera JP (2012) SOX2 regulates the hypothalamic-pituitary axis at multiple levels. J Clin Invest 122:3635\u20133646","journal-title":"J Clin Invest"},{"key":"3523_CR31","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1210\/er.2009-0008","volume":"30","author":"D Kelberman","year":"2009","unstructured":"Kelberman D, Rizzoti K, Lovell-Badge R, Robinson IC, Dattani MT (2009) Genetic regulation of pituitary gland development in human and mouse. Endocr Rev 30:790\u2013829","journal-title":"Endocr Rev"},{"key":"3523_CR32","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/S0925-4773(98)00229-9","volume":"81","author":"C Kioussi","year":"1999","unstructured":"Kioussi C, Carriere C, Rosenfeld MG (1999) A model for the development of the hypothalamic-pituitary axis: transcribing the hypophysis. Mech Dev 81:23\u201335","journal-title":"Mech Dev"},{"key":"3523_CR33","doi-asserted-by":"publisher","first-page":"959","DOI":"10.1242\/dev.128.6.959","volume":"128","author":"T Kouki","year":"2001","unstructured":"Kouki T, Imai H, Aoto K, Eto K, Shioda S, Kawamura K, Kikuyama S (2001) Developmental origin of the rat adenohypophysis prior to the formation of Rathke\u2019s pouch. Development 128:959\u2013963","journal-title":"Development"},{"key":"3523_CR34","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1210\/me.2012-1407","volume":"27","author":"D Langlais","year":"2013","unstructured":"Langlais D, Couture C, Kmita M, Drouin J (2013) Adult pituitary cell maintenance: lineage-specific contribution of self-duplication. Mol Endocrinol 27:1103\u20131112","journal-title":"Mol Endocrinol"},{"key":"3523_CR35","doi-asserted-by":"publisher","first-page":"2382","DOI":"10.1634\/stemcells.2006-0085","volume":"24","author":"DA Lepore","year":"2006","unstructured":"Lepore DA, Jokubaitis VJ, Simmons PJ, Roeszler KN, Rossi R, Bauer K, Thomas PQ (2006) A role for angiotensin-converting enzyme in the characterization, enrichment, and proliferation potential of adult murine pituitary colony-forming cells. Stem Cells 24:2382\u20132390","journal-title":"Stem Cells"},{"key":"3523_CR36","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.yexcr.2005.04.023","volume":"308","author":"DA Lepore","year":"2005","unstructured":"Lepore DA, Roeszler K, Wagner J, Ross SA, Bauer K, Thomas PQ (2005) Identification and enrichment of colony-forming cells from the adult murine pituitary. Exp Cell Res 308:166\u2013176","journal-title":"Exp Cell Res"},{"key":"3523_CR37","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1038\/nrg952","volume":"3","author":"H Lin","year":"2002","unstructured":"Lin H (2002) The stem-cell niche theory: lessons from flies. Nat Rev Genet 3:931\u2013940","journal-title":"Nat Rev Genet"},{"key":"3523_CR38","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1006\/bbrc.1993.1907","volume":"194","author":"H Matsumoto","year":"1993","unstructured":"Matsumoto H, Ishibashi Y, Ohtaki T, Hasegawa Y, Koyama C, Inoue K (1993) Newly established murine pituitary folliculo-stellate-like cell line (TtT\/GF) secretes potent pituitary glandular cell survival factors, one of which corresponds to metalloproteinase inhibitor. Biochem Biophys Res Commun 194:909\u2013915","journal-title":"Biochem Biophys Res Commun"},{"key":"3523_CR39","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1016\/j.yexcr.2003.09.018","volume":"292","author":"C Mogi","year":"2004","unstructured":"Mogi C, Miyai S, Nishimura Y, Fukuro H, Yokoyama K, Takaki A, Inoue K (2004) Differentiation of skeletal muscle from pituitary folliculo-stellate cells and endocrine progenitor cells. Exp Cell Res 292:288\u2013294","journal-title":"Exp Cell Res"},{"key":"3523_CR40","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1016\/0006-291X(65)90320-7","volume":"19","author":"BW Moore","year":"1965","unstructured":"Moore BW (1965) A soluble protein characteristic of the nervous system. Biochem Biophys Res Commun 19:739\u2013744","journal-title":"Biochem Biophys Res Commun"},{"key":"3523_CR41","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1016\/0006-8993(80)91300-1","volume":"191","author":"T Nakajima","year":"1980","unstructured":"Nakajima T, Yamaguchi H, Takahashi K (1980) S100 protein in folliculostellate cells of the rat pituitary anterior lobe. Brain Res 191:523\u2013531","journal-title":"Brain Res"},{"key":"3523_CR42","doi-asserted-by":"publisher","first-page":"2269","DOI":"10.1242\/dev.093294","volume":"140","author":"E Nitzan","year":"2013","unstructured":"Nitzan E, Krispin S, Pfaltzgraff ER, Klar A, Labosky PA, Kalcheim C (2013) A dynamic code of dorsal neural tube genes regulates the segregation between neurogenic and melanogenic neural crest cells. Development 140:2269\u20132279","journal-title":"Development"},{"key":"3523_CR43","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1046\/j.1365-2826.1998.00191.x","volume":"10","author":"LA Nolan","year":"1998","unstructured":"Nolan LA, Kavanagh E, Lightman SL, Levy A (1998) Anterior pituitary cell population control: basal cell turnover and the effects of adrenalectomy and dexamethasone treatment. J Neuroendocrinol 10:207\u2013215","journal-title":"J Neuroendocrinol"},{"key":"3523_CR44","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1046\/j.1365-2826.1999.00333.x","volume":"11","author":"LA Nolan","year":"1999","unstructured":"Nolan LA, Lunness HR, Lightman SL, Levy A (1999) The effects of age and spontaneous adenoma formation on trophic activity in the rat pituitary gland: a comparison with trophic activity in the human pituitary and in human pituitary adenomas. J Neuroendocrinol 11:393\u2013401","journal-title":"J Neuroendocrinol"},{"key":"3523_CR45","doi-asserted-by":"crossref","unstructured":"O\u2019Hara L, Christian HC, Jeffery N, Le Tissier P, Smith LB (2020) Characterisation of a mural cell network in the murine pituitary gland. J Neuroendocrinol 32:e12903","DOI":"10.1111\/jne.12903"},{"key":"3523_CR46","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1530\/JOE-12-0043","volume":"213","author":"M Osuna","year":"2012","unstructured":"Osuna M, Sonobe Y, Itakura E, Devnath S, Kato T, Kato Y, Inoue K (2012) Differentiation capacity of native pituitary folliculostellate cells and brain astrocytes. J Endocrinol 213:231\u2013237","journal-title":"J Endocrinol"},{"key":"3523_CR47","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1002\/stem.3283","volume":"39","author":"SN Perera","year":"2021","unstructured":"Perera SN, Kerosuo L (2021) On the road again: establishment and maintenance of stemness in the neural crest from embryo to adulthood. Stem Cells 39:7\u201325","journal-title":"Stem Cells"},{"key":"3523_CR48","doi-asserted-by":"crossref","unstructured":"Perez Millan MI, Brinkmeier ML, Mortensen AH, Camper SA (2016) PROP1 triggers epithelial-mesenchymal transition-like process in pituitary stem cells. Elife 5:e14470","DOI":"10.7554\/eLife.14470"},{"key":"3523_CR49","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1089\/scd.2006.15.286","volume":"15","author":"C Pierret","year":"2006","unstructured":"Pierret C, Spears K, Maruniak JA, Kirk MD (2006) Neural crest as the source of adult stem cells. Stem Cells Dev 15:286\u2013291","journal-title":"Stem Cells Dev"},{"key":"3523_CR50","doi-asserted-by":"publisher","first-page":"1707","DOI":"10.1126\/science.1553558","volume":"255","author":"BA Reynolds","year":"1992","unstructured":"Reynolds BA, Weiss S (1992) Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255:1707\u20131710","journal-title":"Science"},{"key":"3523_CR51","doi-asserted-by":"publisher","first-page":"R55","DOI":"10.1530\/JME-14-0237","volume":"54","author":"K Rizzoti","year":"2015","unstructured":"Rizzoti K (2015) Genetic regulation of murine pituitary development. J Mol Endocrinol 54:R55-73","journal-title":"J Mol Endocrinol"},{"key":"3523_CR52","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1016\/j.stem.2013.07.006","volume":"13","author":"K Rizzoti","year":"2013","unstructured":"Rizzoti K, Akiyama H, Lovell-Badge R (2013) Mobilized adult pituitary stem cells contribute to endocrine regeneration in response to physiological demand. Cell Stem Cell 13:419\u2013432","journal-title":"Cell Stem Cell"},{"key":"3523_CR53","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.mce.2016.08.020","volume":"445","author":"K Rizzoti","year":"2017","unstructured":"Rizzoti K, Lovell-Badge R (2017) Pivotal role of median eminence tanycytes for hypothalamic function and neurogenesis. Mol Cell Endocrinol 445:7\u201313","journal-title":"Mol Cell Endocrinol"},{"key":"3523_CR54","doi-asserted-by":"publisher","first-page":"16940","DOI":"10.1038\/s41598-017-16796-2","volume":"7","author":"H Roose","year":"2017","unstructured":"Roose H, Cox B, Boretto M, Gysemans C, Vennekens A, Vankelecom H (2017) Major depletion of SOX2(+) stem cells in the adult pituitary is not restored which does not affect hormonal cell homeostasis and remodelling. Sci Rep 7:16940","journal-title":"Sci Rep"},{"key":"3523_CR55","doi-asserted-by":"publisher","first-page":"1809","DOI":"10.1126\/science.278.5344.1809","volume":"278","author":"HZ Sheng","year":"1997","unstructured":"Sheng HZ, Moriyama K, Yamashita T, Li H, Potter SS, Mahon KA, Westphal H (1997) Multistep control of pituitary organogenesis. Science 278:1809\u20131812","journal-title":"Science"},{"key":"3523_CR56","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1007\/BF00222177","volume":"231","author":"N Shirasawa","year":"1983","unstructured":"Shirasawa N, Kihara H, Yamaguchi S, Yoshimura F (1983) Pituitary folliculo-stellate cells immunostained with S-100 protein antiserum in postnatal, castrated and thyroidectomized rats. Cell Tissue Res 231:235\u2013249","journal-title":"Cell Tissue Res"},{"key":"3523_CR57","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1242\/dev.105445","volume":"142","author":"M Simoes-Costa","year":"2015","unstructured":"Simoes-Costa M, Bronner ME (2015) Establishing neural crest identity: a gene regulatory recipe. Development 142:242\u2013257","journal-title":"Development"},{"key":"3523_CR58","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1038\/384327a0","volume":"384","author":"MW Sornson","year":"1996","unstructured":"Sornson MW, Wu W, Dasen JS, Flynn SE, Norman DJ, O\u2019Connell SM, Gukovsky I, Carriere C, Ryan AK, Miller AP, Zuo L, Gleiberman AS, Andersen B, Beamer WG, Rosenfeld MG (1996) Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism. Nature 384:327\u2013333","journal-title":"Nature"},{"key":"3523_CR59","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1210\/mend.12.3.0073","volume":"12","author":"JJ Tremblay","year":"1998","unstructured":"Tremblay JJ, Lanctot C, Drouin J (1998) The pan-pituitary activator of transcription, Ptx1 (pituitary homeobox 1), acts in synergy with SF-1 and Pit-1 and is an upstream regulator of the Lim-homeodomain gene Lim3\/Lhx3. Mol Endocrinol 12:428\u2013441","journal-title":"Mol Endocrinol"},{"key":"3523_CR60","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1007\/s00441-018-02989-2","volume":"376","author":"T Tsukada","year":"2019","unstructured":"Tsukada T, Isowa Y, Kito K, Yoshida S, Toneri S, Horiguchi K, Fujiwara K, Yashiro T, Kato T, Kato Y (2019) Identification of TGF\u03b2-induced proteins in non-endocrine mouse pituitary cell line TtT\/GF by SILAC-assisted quantitative mass spectrometry. Cell Tissue Res 376:281\u2013293","journal-title":"Cell Tissue Res"},{"key":"3523_CR61","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1007\/s00441-017-2758-x","volume":"371","author":"T Tsukada","year":"2017","unstructured":"Tsukada T, Yoshida S, Kito K, Fujiwara K, Yako H, Horiguchi K, Isowa Y, Yashiro T, Kato T, Kato Y (2017) TGFbeta signaling reinforces pericyte properties of the non-endocrine mouse pituitary cell line TtT\/GF. Cell Tissue Res 371:339\u2013350","journal-title":"Cell Tissue Res"},{"key":"3523_CR62","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1007\/s00441-017-2724-7","volume":"372","author":"H Ueharu","year":"2018","unstructured":"Ueharu H, Yoshida S, Kanno N, Horiguchi K, Nishimura N, Kato T, Kato Y (2018) SOX10-positive cells emerge in the rat pituitary gland during late embryogenesis and start to express S100beta. Cell Tissue Res 372:77\u201390","journal-title":"Cell Tissue Res"},{"key":"3523_CR63","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1111\/joa.12572","volume":"230","author":"H Ueharu","year":"2017","unstructured":"Ueharu H, Yoshida S, Kikkawa T, Kanno N, Higuchi M, Kato T, Osumi N, Kato Y (2017) Gene tracing analysis reveals the contribution of neural crest-derived cells in pituitary development. J Anat 230:373\u2013380","journal-title":"J Anat"},{"key":"3523_CR64","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1016\/j.semcdb.2007.04.006","volume":"18","author":"H Vankelecom","year":"2007","unstructured":"Vankelecom H (2007a) Non-hormonal cell types in the pituitary candidating for stem cell. Semin Cell Dev Biol 18:559\u2013570","journal-title":"Semin Cell Dev Biol"},{"key":"3523_CR65","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1159\/000100278","volume":"85","author":"H Vankelecom","year":"2007","unstructured":"Vankelecom H (2007b) Stem cells in the postnatal pituitary? Neuroendocrinology 85:110\u2013130","journal-title":"Neuroendocrinology"},{"key":"3523_CR66","doi-asserted-by":"publisher","first-page":"36","DOI":"10.2174\/157488812798483467","volume":"7","author":"H Vankelecom","year":"2012","unstructured":"Vankelecom H (2012) Pituitary stem cells drop their mask. Curr Stem Cell Res Ther 7:36\u201371","journal-title":"Curr Stem Cell Res Ther"},{"key":"3523_CR67","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.mce.2013.08.018","volume":"385","author":"H Vankelecom","year":"2014","unstructured":"Vankelecom H, Chen J (2014) Pituitary stem cells: where do we stand? Mol Cell Endocrinol 385:2\u201317","journal-title":"Mol Cell Endocrinol"},{"key":"3523_CR68","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1016\/j.ygcen.2009.11.007","volume":"166","author":"H Vankelecom","year":"2010","unstructured":"Vankelecom H, Gremeaux L (2010) Stem cells in the pituitary gland: a burgeoning field. Gen Comp Endocrinol 166:478\u2013488","journal-title":"Gen Comp Endocrinol"},{"issue":"Suppl 1","key":"3523_CR69","doi-asserted-by":"publisher","first-page":"S110","DOI":"10.1016\/j.ydbio.2018.05.013","volume":"444","author":"GA Vega-Lopez","year":"2018","unstructured":"Vega-Lopez GA, Cerrizuela S, Tribulo C, Aybar MJ (2018) Neurocristopathies: new insights 150 years after the neural crest discovery. Dev Biol 444(Suppl 1):S110\u2013S143","journal-title":"Dev Biol"},{"key":"3523_CR70","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1007\/BF00307293","volume":"129","author":"E Vila-Porcile","year":"1972","unstructured":"Vila-Porcile E (1972) The network of the folliculo-stellate cells and the follicles of the adenohypophysis in the rat (pars distalis). Z Zellforsch Mikrosk Anat 129:328\u2013369","journal-title":"Z Zellforsch Mikrosk Anat"},{"key":"3523_CR71","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1002\/cne.10552","volume":"457","author":"V Vives","year":"2003","unstructured":"Vives V, Alonso G, Solal AC, Joubert D, Legraverend C (2003) Visualization of S100B-positive neurons and glia in the central nervous system of EGFP transgenic mice. J Comp Neurol 457:404\u2013419","journal-title":"J Comp Neurol"},{"key":"3523_CR72","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.neulet.2009.06.059","volume":"465","author":"XY Wei","year":"2009","unstructured":"Wei XY, Zhao CH, Liu YY, Wang YZ, Ju G (2009) Immuohistochemical markers for pituicyte. Neurosci Lett 465:27\u201330","journal-title":"Neurosci Lett"},{"key":"3523_CR73","doi-asserted-by":"crossref","unstructured":"Yamashita M, Qian ZR, Sano T, Horvath E, Kovacs K (2005) Immunohistochemical study on so-called follicular cells and folliculostellate cells in the human adenohypophysis. Pathol Int 55:244\u2013247","DOI":"10.1111\/j.1440-1827.2005.01820.x"},{"key":"3523_CR74","doi-asserted-by":"publisher","first-page":"8893703","DOI":"10.1155\/2020\/8893703","volume":"2020","author":"L-N Yang","year":"2020","unstructured":"Yang L-N, Huang W-K, Li X-L, Bai Y-Z, Zhang S-C (2020) Sox10 is a specific biomarker for neural crest stem cells in immunohistochemical staining in Wistar rats. Dis Markers 2020:8893703","journal-title":"Dis Markers"},{"key":"3523_CR75","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1262\/jrd.2014-031","volume":"60","author":"S Yoshida","year":"2014","unstructured":"Yoshida S, Higuchi M, Ueharu H, Nishimura N, Tsuda M, Nishihara H, Mitsuishi H, Kato T, Kato Y (2014) Characterization of murine pituitary-derived cell lines Tpit\/F1, Tpit\/E and TtT\/GF. J Reprod Dev 60:295\u2013303","journal-title":"J Reprod Dev"},{"key":"3523_CR76","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1007\/s00441-014-2054-y","volume":"359","author":"S Yoshida","year":"2015","unstructured":"Yoshida S, Kato T, Chen M, Higuchi M, Ueharu H, Nishimura N, Kato Y (2015) Localization of juxtacrine factor ephrin-B2 in pituitary stem\/progenitor cell niches throughout life. Cell Tissue Res 359:755\u2013766","journal-title":"Cell Tissue Res"},{"key":"3523_CR77","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1111\/jne.12077","volume":"25","author":"S Yoshida","year":"2013","unstructured":"Yoshida S, Kato T, Higuchi M, Yako H, Chen M, Kanno N, Ueharu H, Kato Y (2013) Rapid transition of NESTIN-expressing dividing cells from PROP1-positive to PIT1-positive advances prenatal pituitary development. J Neuroendocrinol 25:779\u2013791","journal-title":"J Neuroendocrinol"},{"key":"3523_CR78","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1007\/s00441-017-2646-4","volume":"370","author":"S Yoshida","year":"2017","unstructured":"Yoshida S, Kato T, Kanno N, Nishimura N, Nishihara H, Horiguchi K, Kato Y (2017) Cell type-specific localization of Ephs pairing with ephrin-B2 in the rat postnatal pituitary gland. Cell Tissue Res 370:99\u2013112","journal-title":"Cell Tissue Res"},{"key":"3523_CR79","doi-asserted-by":"publisher","first-page":"43","DOI":"10.3390\/jcm5040043","volume":"5","author":"S Yoshida","year":"2016","unstructured":"Yoshida S, Kato T, Kato Y (2016a) EMT Involved in migration of stem\/progenitor cells for pituitary development and regeneration. J Clin Med 5:43","journal-title":"J Clin Med"},{"key":"3523_CR80","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1111\/j.1365-2826.2011.02198.x","volume":"23","author":"S Yoshida","year":"2011","unstructured":"Yoshida S, Kato T, Yako H, Susa T, Cai LY, Osuna M, Inoue K, Kato Y (2011) Significant quantitative and qualitative transition in pituitary stem\/progenitor cells occurs during the postnatal development of the rat anterior pituitary. J Neuroendocrinol 23:933\u2013943","journal-title":"J Neuroendocrinol"},{"key":"3523_CR81","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/j.scr.2016.08.016","volume":"17","author":"S Yoshida","year":"2016","unstructured":"Yoshida S, Nishimura N, Ueharu H, Kanno N, Higuchi M, Horiguchi K, Kato T, Kato Y (2016b) Isolation of adult pituitary stem\/progenitor cell clusters located in the parenchyma of the rat anterior lobe. Stem Cell Res 17:318\u2013329","journal-title":"Stem Cell Res"},{"key":"3523_CR82","doi-asserted-by":"crossref","unstructured":"Yoshida S, Nishimura N, Yurino H, Kobayashi M, Horiguchi K, Yano K, Hashimoto S, Kato T, Kato Y (2018) Differentiation capacities of PS-clusters, adult pituitary stem\/progenitor cell clusters located in the parenchymal-niche, of the rat anterior lobe. PLoS One 13:e0196029","DOI":"10.1371\/journal.pone.0196029"},{"key":"3523_CR83","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1507\/endocrj1954.24.301","volume":"24","author":"F Yoshimura","year":"1977","unstructured":"Yoshimura F, Soji T, Kiguchi Y (1977a) Relationship between the follicular cells and marginal layer cells of the anterior pituitary. Endocr J 24:301\u2013305","journal-title":"Endocr J"},{"key":"3523_CR84","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1507\/endocrj1954.24.435","volume":"24","author":"F Yoshimura","year":"1977","unstructured":"Yoshimura F, Soji T, Sato S, Yokoyama M (1977b) Development and differentiation of rat pituitary follicular cells under normal and some experimental conditions with special reference to an interpretation of renewal cell system. Endocr J 24:435\u2013449","journal-title":"Endocr J"},{"key":"3523_CR85","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1002\/bdrc.21081","volume":"102","author":"D Zhang","year":"2014","unstructured":"Zhang D, Ighaniyan S, Stathopoulos L, Rollo B, Landman K, Hutson J, Newgreen D (2014) The neural crest: a versatile organ system. Birth Defects Res C Embryo Today 102:275\u2013298","journal-title":"Birth Defects Res C Embryo Today"},{"key":"3523_CR86","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1152\/physrev.00006.2006","volume":"87","author":"X Zhu","year":"2007","unstructured":"Zhu X, Gleiberman AS, Rosenfeld MG (2007) Molecular physiology of pituitary development: signaling and transcriptional networks. Physiol Rev 87:933\u2013963","journal-title":"Physiol Rev"},{"key":"3523_CR87","doi-asserted-by":"publisher","first-page":"2739","DOI":"10.1101\/gad.1444706","volume":"20","author":"X Zhu","year":"2006","unstructured":"Zhu X, Zhang J, Tollkuhn J, Ohsawa R, Bresnick EH, Guillemot F, Kageyama R, Rosenfeld MG (2006) Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis. Genes Dev 20:2739\u20132753","journal-title":"Genes Dev"}],"container-title":["Cell and Tissue Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00441-021-03523-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00441-021-03523-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00441-021-03523-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,6]],"date-time":"2023-02-06T22:33:28Z","timestamp":1675722808000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00441-021-03523-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,22]]},"references-count":87,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["3523"],"URL":"https:\/\/doi.org\/10.1007\/s00441-021-03523-7","relation":{},"ISSN":["0302-766X","1432-0878"],"issn-type":[{"value":"0302-766X","type":"print"},{"value":"1432-0878","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,22]]},"assertion":[{"value":"17 September 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 September 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 September 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}